CN105535871A - Traditional Chinese medicine plaster for treating cervical muscle type cervical spondylosis - Google Patents

Traditional Chinese medicine plaster for treating cervical muscle type cervical spondylosis Download PDF

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CN105535871A
CN105535871A CN201610095608.6A CN201610095608A CN105535871A CN 105535871 A CN105535871 A CN 105535871A CN 201610095608 A CN201610095608 A CN 201610095608A CN 105535871 A CN105535871 A CN 105535871A
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parts
cervical
plaster
rhizoma
radix
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
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Abstract

The invention discloses a traditional Chinese medicine plaster for treating cervical muscle type cervical spondylosis. The traditional Chinese medicine plaster is prepared from, by weight, 10-18 parts of night worms, 1-10 parts of fructus chaenomelis, 10-17 parts of radix salviae miltiorrhizae, 5-10 parts of rhizoma seu radix notopterygii, 3-10 parts of rhizoma curcumae longae, 9-13 parts of bungarus fasciatus, 6-15 parts of herba pyrolae, 3-10 parts of radix clematidis, 5-10 parts of rhizomes and roots of veratrum japonicum (Baker) Loes. and 5-9 parts of rhizoma dioscoreae nipponicae. The traditional Chinese medicine plaster has the effects of activating the blood to promote menstruation, stopping pain and dredging collaterals and has a good treating effect on cervical spondylosis and complications thereof.

Description

The Chinese medicinal ointment for the treatment of cervical muscle myelopathy
Divisional application, original applying number 2014101736883, applying date 2014.04.28, title is a kind of treats plaster of cervical muscle myelopathy and preparation method thereof.
Technical field
The invention discloses and a kind ofly treat plaster of cervical muscle myelopathy and preparation method thereof, its dosage form is unguentum, the invention belongs to traditional Chinese medicine field.
Background technology
Cervical spondylosis, also known as cervical spine syndrome, is the general name of osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion, is a kind of illness changing into basis with degeneration pathology.Strain for a long time mainly due to cervical vertebra, hyperosteogeny, or prolapse of intervertebral disc, ligament thicken, and cause cervical vertebra spinal cord, nerve root or vertebral artery pressurized, occur a series of handicapped clinical syndrome.Show as intervertebral disc degradation itself and insecondary a series of pathological change thereof, as vertebra joint unstability, loosen; Nucleus pulposus or deviate from; Bony spur is formed; The spinal canal stenosis etc. of ligament plumpness and secondary, stimulates or has oppressed the tissues such as the nerve root of vicinity, spinal cord, vertebral artery and cervical region sympathetic nerve, cause series of symptoms and sign.
The clinical symptoms of cervical spondylosis is comparatively complicated.Mainly contain nape pain, upper myasthenia of limbs, point numb, lower limb are weak, difficulty in walking, dizziness, Nausea and vomiting, even blurred vision, tachycardia and dysphagia etc.Clinical symptoms and the diseased region of cervical spondylosis, involved and individual variation is organized to have certain relation.
The inspection method of cervical spondylosis comprises following several.
1, the test inspection of cervical spondylosis and physical examination, comprising: (1) is anteflexion revolves neck test.Make patient's cervical region anteflexion, advise its rotary moveable to the left and right.As cervical vertebra there is pain in place, shows that cervical facet joint has degeneration; (2) intervertebral foramina squeeze test (test of bearing down on one).Make patient's head be partial to Ipsilateral, examiner's left hand palm be put in patient's head, the right hand the is clenched fist tapping left hand back of the body, then there is limbs radiating pain or numbness, expression strength going down diminish to intervertebral foramina, have root to damage; To root pain severity person, examiner with the hands overlap be put in the crown, under pressurization, can bring out or aggravate symptom.When patients head be in neutral position or after to stretch time to occur that the applied voltage test positive is referred to as Jackson head test positive; (3) brachial plexus distraction test.Patient bows, the hand steered patient's incidence of examiner one, another holds suffering limb wrist, and do rightabout push-and-pull, see whether patient feels radiating pain or numbness, this is called that Eaten tests.As tractive forces suffering limb to make pronation more simultaneously, be then called that Eaten strengthens test; (4) test is stretched after upper limb.Examiner is placed on the other hand that fixation is played in healthy side shoulder portion, another is held in patient's wrist, and makes it gradually backward, outward in stretch-like, to increase cervical nerve root tractive, if radiating pain appears in suffering limb, show that cervical nerve root or brachial plexus have pressurized or damage.2, x-ray inspection.The male of normal more than 40 years old, the bony spur that the women of more than 45 years old about has 90% to there is cervical vertebral body.Therefore have the change of x-ray plain film, not necessarily there is clinical symptoms.Now relevant with cervical spondylosis x-ray finding is described below: (1) normotopia.Observe with or without pivot ring joint dislocation, odontoid fracture or disappearance.C7 transverse process with or without long, with or without cervical rib.Uncovertebral joint and intervertebral space are with or without broadening or narrow; (2) position, side.1. the change of curvature.Cervical vertebra is sent out directly, physiology prolapse disappears or contraflexure; 2. abnormal movement degree.Cross at cervical vertebra and extend through in the X-ray film of position, side in the wrong, the elasticity can seeing intervertebral disc changes; 3. hyperosteogeny.All hyperosteogeny and ligament calcification can be produced close to the position of intervertebral disc before and after vertebral body; 4. narrowing of intervertebral space.Intervertebral disc can because of Nucleus pulposus, and intervertebral disc water content reduces fibre modification and thinning occurs, and shows on X-ray film to be narrowing of intervertebral space.5. subluxation and intervertebral foramina diminish.After degeneration of intervertebral disc, interpyramidal poor stability, often there is subluxation in vertebral body, or is referred to as sliding vertebra; 6. ligamentum nuchae ossification.Ligamentum nuchae ossification is one of typical cytopathic of cervical spondylosis; (3) loxosis.Take the photograph vertebra left and right oblique film, be mainly used to observe the size of intervertebral foramina and the situation of uncovertebral joint hyperosteogeny.3, electromyography.The electromyography of cervical spondylosis and prolapse of cervical intervertebral disc all can be pointed out the long-term pressurized of nerve root and degeneration occurs, thus loses the inhibitory action to arranged muscle.4, CT examination.The canalis spinalis of CT for diagnosing ossification of posterior longitudinal ligament, spinal canal stenosis, tumor of spinal cord etc. caused expands or bone destruction, measures bone density to estimate osteoporotic degree.In addition, because cross fault image clearly can see soft tissue inside and outside dural sheath and subarachnoid space.Therefore correctly can diagnose the empty disease of intervertebral disc prolapse, neurofibroma, spinal cord or oblongata, for the diagnosis of cervical spondylosis and Differential Diagnosis, there is certain value.
If cervical spondylosis treatment not in time, can cause the appearance of complication for a long time, complication of cervical spondylopathy disease mainly contains following several.
1, dysphagia.Have when swallowing in sense of obstruction, esophagus and have foreign body sensation, a few peoples have Nausea and vomiting, hoarseness, dry cough, the symptom such as uncomfortable in chest.This directly oppresses esophagus rear wall due to cervical vertebra leading edge and causes esophagostenosis, also may be because bony spur is formed to overrun, esophagus surrounding soft tissue to be occurred caused by irritant reaction.2, visual disorder.Show as visual deterioration, ophthalmic bloated pain, keep in dark place, shed tears, pupil size not etc., even occur that constriction of visual field and vision fall sharply, few patients also can occur blind.This and cervical spondylosis cause autonomic nervous dysfunction and vertebral-basilar artery insufficiency and the brain occipital lobe visual centre ischemic disease damage caused is relevant.3, neck heart syndrome.Show as precordialgia, uncomfortable in chest, arrhythmia (as premature beat etc.) and ECG ST section to change, be easily misdiagnosed as coronary heart disease.This is nape nerve root by caused by the stimulation of cervical osteophytes and compressing.4, hypertension cervical spondylosis.Can cause elevation of the blood pressure or reduce, be wherein many with blood pressure rising, be called " neck hypertension ".Because cervical spondylosis and hypertension are all the commonly encountered diseases of middle-aged and elderly people, therefore both usually and deposit.5, chest pain.Show as onset obstinate one-sided pectoralis major and mastalgia slowly, during inspection, have pectoralis major tenderness.This oppresses relevant with neck 6 and C7nerve root by cervical osteophytes.6, lower extremity paralysis.Early manifestation is numbness of lower limbs, pain, limping, and some patients are when walking just like the sensation of stepping on Cotton Gossypii, and few patients also can with defecation, dysuria, as frequent micturition, urgent micturition, urinate smooth or gatism etc.This is because vertebral body lateral bundle is subject to stimulation or the compressing of cervical osteophytes, cause caused by lower extremity movement and sensory disturbance.7, damping off.Be everlasting when standing or walk and occur that health loses holding power and dampings off because turning one's head suddenly, can regain consciousness very soon after falling down to the ground, without disturbance of consciousness, also no sequel.This type of patient can with the symptom of the autonomic nervous dysfunctions such as dizziness, Nausea and vomiting, perspiration.This causes basilar arterial blood supply obstacle because hyperosteogeny sexually revises compressing vertebral artery, causes caused by momentary cerebral blood supply insufficiency.
In the invention of existing treatment cervical muscle myelopathy, Authorization Notice No. CN102406789B(application number 201110393441.9) Chinese patent disclose a kind of plaster for the treatment of cervical spondylosis: Radix Angelicae Sinensis 30 grams, Radix Salviae Miltiorrhizae 40 grams, Herba Aristolochiae Mollissimae 35 grams, Formica fusca 35 grams, Semen Sinapis Albae 40 grams, Radix Achyranthis Bidentatae 30 grams, Fructus Foeniculi 35 grams, Radix Aconiti Kusnezoffii 20 grams, Rhizoma Chuanxiong 30 grams, Scolopendra 20 grams, Scorpio 30 grams, Semen Strychni 30 grams, Sanguis Draxonis 30 grams, Myrrha 40 grams, Olibanum 30 grams, Borneolum Syntheticum 30 grams, preparation method: get Radix Angelicae Sinensis 30 grams, Radix Salviae Miltiorrhizae 40 grams, Herba Aristolochiae Mollissimae 35 grams, Formica fusca 35 grams, Semen Sinapis Albae 40 grams, Radix Achyranthis Bidentatae 30 grams, Fructus Foeniculi 35 grams, Radix Aconiti Kusnezoffii 20 grams, Rhizoma Chuanxiong 30 grams, Scolopendra 20 grams, Scorpio 30 grams, Semen Strychni 30 grams, add 5 times to the water of said medicine weight, slow fire boiling is dragged for slag after 60 minutes and is made decoction, Sanguis Draxonis 30 grams is added in decoction, Myrrha 40 grams, Olibanum 30 grams, Borneolum Syntheticum 30 grams, slow fire be heated to agent dissolving after, add Plumbum preparatium again and make ointment, cream of getting it filled evenly is applied on the cloth of stand and makes plaster, every 10 gram of one subsides, if life-time service easily produces drug resistance.Application publication number CN103230447A(application number 201310115163.X) Chinese patent disclose a kind of external medicine wine for the treatment of cervical spondylosis, formula and part by weight are Semen Strychni 10 parts, Pheropsophus jessoensis Mor. 20 parts, Radix Aconiti 12 parts, Radix Aconiti Kusnezoffii 10 parts, Radix Clematidis 20 parts, Hirudo 15 parts, Bungarus fasciatus 15 parts, Caulis Spatholobi 25 parts, Borneolum Syntheticum 6 parts; Above-mentioned raw materials medicine is weighed in proportion and assorts, with pharmaceutical equipment apparatus concoct qualified, purify, concentrated make fine powder after to adjust in 1:100 ratio with 75% ethanol or 600 Chinese liquor that to convert into medicated wine for subsequent use, it is very fast to smear rear volatilization, cannot continuingly act on affected part.
Summary of the invention
For existing current treatment status, an object of the present invention is to provide a kind of plaster for the treatment of cervical muscle myelopathy, not only has blood circulation promoting and blood stasis dispelling, the effect of inducing menstruation to relieve menalgia, also have administration time lasting for a long time, active constituent content is high, and local efficacy is the feature such as definite obviously.
Another object of the present invention is just to provide the preparation method of the plaster of above-mentioned treatment cervical muscle myelopathy.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of plaster for the treatment of cervical muscle myelopathy, take off the primary raw material stating weight proportion to be prepared from: Pheropsophus jessoensis Mor. 10-18 part, Fructus Chaenomelis 1-10 part, Radix Salviae Miltiorrhizae 10-17 part, Rhizoma Et Radix Notopterygii 5-10 part, Rhizoma Curcumae Longae 3-10 part, Bungarus fasciatus 9-13 part, Herba Pyrolae 6-15 part, Radix Clematidis 3-10 part, seven lis of red 5-10 parts, Rhizoma Dioscoreae Nipponicae 5-9 part.
The plaster of above-mentioned treatment cervical muscle myelopathy, preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 13-16 part, Fructus Chaenomelis 3-7 part, Radix Salviae Miltiorrhizae 13-15 part, Rhizoma Et Radix Notopterygii 7-9 part, Rhizoma Curcumae Longae 5-8 part, Bungarus fasciatus 10-12 part, Herba Pyrolae 10-12 part, Radix Clematidis 5-8 part, seven lis of red 6-9 parts, Rhizoma Dioscoreae Nipponicae 6-8 part.
The plaster of the above treatment cervical muscle myelopathy, better preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 15 parts, Fructus Chaenomelis 5 parts, Radix Salviae Miltiorrhizae 14 parts, Rhizoma Et Radix Notopterygii 8 parts, 6 parts, Rhizoma Curcumae Longae, Bungarus fasciatus 11 parts, Herba Pyrolae 11 parts, Radix Clematidis 7 parts, seven lis of pellets 8 parts, Rhizoma Dioscoreae Nipponicae 7 parts.
According to the preparation method of the plaster of arbitrary described treatment cervical muscle myelopathy above, step is as follows:
1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and leaves standstill 10-20 days, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. by step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolae, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 20-40 minute, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 5-10 hour, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C-80 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 5-15g to spread upon in adhesive plaster or other substrate, make plaster.
According to above-mentioned preparation method, preferred scheme is: 1. step leaves standstill 13-18 days (preferably 15 days).
According to above-mentioned preparation method, preferred scheme is: 2. step decocts to 25-35 minute (preferably 30 minutes).
According to above-mentioned preparation method, preferred scheme is: 3. step leaves standstill 7-9 hour (preferably 8 hours).
According to above-mentioned preparation method, preferred scheme is: step 4. 65 DEG C-75 DEG C (preferably 70 DEG C).
According to above-mentioned preparation method, preferred scheme is: the weight ratio of step 4. vegetable oil, Colophonium, white vaseline and distillate is 1:1.5:1.5:1.
According to the application of plaster when the medicine of preparation treatment cervical spondylotic myelopathy, spondylotic radiculopathy cervical muscle myelopathy of the treatment cervical muscle myelopathy above described in any one.
Best using method: be the therapeutic effect making the present invention reach best, plaster is directly affixed on uncomfortable cervical vertebra place, gently seals about 1 minute after subsides with palm, and pasting and wear 12 hours, every day 1 time, 10 days is a course for the treatment of.
Treat a plaster for cervical muscle myelopathy, the pharmacological effect of each raw material is respectively:
Pheropsophus jessoensis Mor.: base is former: for Carabidae step cape belongs to the Scorpio of animal tiger spot cloth cape.The property of medicine: pungent, temperature.Function cures mainly: blood circulation promoting and blood stasis dispelling, removing obstruction for relieving pain.Cure mainly amenorrhea due to stagnation of blood, dysmenorrhea, the stagnant stomachache of the stasis of blood in puerperal, lump in the abdomen, traumatic injury stasis of blood pain.
Fructus Chaenomelis: sour in the mouth, warm in nature.Return liver, spleen channel.Effect: suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness.Cure mainly: arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, convulsion of vomiting and diarrhoea, beriberi edema.
Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature.GUIXIN, Liver Channel.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.Cure mainly: menoxenia, amenorrhea dysmenorrhea ， lumps in the chest and abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection swells and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature.Return bladder, kidney channel.Effect: cold expelling, dispels the wind, dehumidifying, pain relieving.Cure mainly: anemofrigid cold is had a headache, rheumatic arthralgia, aching pain in should and back.
Rhizoma Curcumae Longae: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel.Effect: removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia.Cure mainly: amenorrhea due to stagnation of blood, menalgia, the twinge of the breast side of body, rheumatic arthralgia, shoulder arm pain, injury from falling down.
Bungarus fasciatus: base is former: be the entirety of Elapidae Bungarus animal Bungarus fasciatus removing internal organs.Composition: meat is containing 21 kinds of trace element such as protein, aminoacid, fat and ferrum, aluminum, pungent, strontium, titanium, manganese, copper, barium.Containing pseudocholinesterase in serum.Another containing echidnotoxin and peptide: blue bungarotoxin, Bungarus fasciatus toxin A, B etc.The property of medicine: " Guangxi Chinese medicinal herbal ": " salty in the mouth, warm in nature.Enter Liver Channel." function cures mainly: dispel the wind, dehumidifying, dredging collateral, pain relieving.Cure mainly rheumatoid arthritis stubborn, numb limbs and tense tendons, the anxious pain of contraction, paralysis due to windstroke, hemiplegia.Compatibility and incompatibility of drugs: " Guangxi Chinese medicinal herbal ": " numbness as belonged to the dry muscle of blood withered avoids use." Herba Pyrolae: sweet in the mouth, hardship, warm in nature.Return liver, kidney channel.Effect: wind-damp dispelling, bone and muscle strengthening, hemostasis.Cure mainly: rheumatic arthralgia, weakness of the waist and knees, menorrhagia, chronic cough due to asthenia of viscera.
Radix Clematidis: acrid in the mouth, salty, warm in nature.Return urinary bladder channel.Effect: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.Curing mainly: rheumatic arthralgia. numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness, bone chokes down larynx.
Seven lis of pellets: base is former: be rhizome and the root of the black purple Rhizoma et radix veratri (Radix Rhizoma Veratri) of Liliaceae Veratrum.The property of medicine: " Guangxi book on Chinese herbal medicine a collection of selected materials ": " bitter in the mouth is pungent, cold in nature, very toxic." function cures mainly: gush expectorant, dissipating blood stasis, pain relieving, parasite killing, eliminating stasis to stop pain.Cure mainly apoplexy, demented accumulation and obstruction of sputum, traumatic injury, malignant boil, scabies.Compatibility and incompatibility of drugs: " Fujian medicine will ": " be not taken by pregnant women.Can not with all ginsengs, Herba Asari, Radix Paeoniae compatibility." Rhizoma Dioscoreae Nipponicae: salty in the mouth, cold nature.Return liver, stomach warp.Effect: stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, expel wind to dredge collateral.Cure mainly: amenorrhea and mass in the abdomen, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.
Rhizoma Dioscoreae Nipponicae: return liver, kidney, lung meridian, warm in nature, sweet in the mouth, hardship.Relaxing muscles and tendons to promote blood circulation, relieving cough and resolving phlegm, wind-expelling pain-stopping.For lumbago and skelalgia, rheumatalgia, rheumatic arthritis, muscles and bones numbness, Kaschin-Beck disease, traumatic injury, sprain one's back, cough pant, tracheitis, bronchitis.
Colophonium, vegetable oil, white vaseline are excipient, play the effect of mediation figuration.Plaster is the large dosage form-ball of Chinese medicine five, loose, one of cream, pellet, soup.Ancient doctor's speech is said: " plaster can be cured the disease, and not different from decoction, does in the proper way with it, and it rings vertical answering." prescription of the present invention all selects Xin Xiang to walk to go here and there extremely strong tying-in medicine, medicine directly infiltrates through skin, by interior transmission from one channel to another network, plays disperse blood stasis and dredge collateral, the effect that pain relieving is stimulated the menstrual flow.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 10 parts, Fructus Chaenomelis 1 part, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Et Radix Notopterygii 5 parts, 3 parts, Rhizoma Curcumae Longae, Bungarus fasciatus 9 parts, Herba Pyrolae 6 parts, Radix Clematidis 3 parts, seven lis of pellets 5 parts, Rhizoma Dioscoreae Nipponicae 5 parts.
The preparation method of the plaster of above-mentioned treatment cervical muscle myelopathy, step is:
1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and leaves standstill 10 days, and filtration, obtains filtrate and filtering residue is for subsequent use;
2. by step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolae, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 20 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 5 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 5g to spread upon in adhesive plaster or other substrate, make plaster.
Typical case one king XX, man, 55 years old, people from Qingzhou, Weifang City, workman.Long-term at factory work, cervical muscle myelopathy history 1 year, cervicodynia is uncomfortable in chest, and with the symptom of blurred vision, nearest right arm sensation grips unable, and health has constrained sense, couches night and all feels uncomfortable, cannot fall asleep and cause lethargy.Check and find patient's instability of gait, hands grasping power is all not high, and right arm situation is even more serious, and compression of spinal cord is comparatively obvious, seeks medical advice everywhere, all to no effect, sees plaster of the present invention unintentionally on newspaper, have the attitude of trying in arms and bought 2 courses for the treatment of.
Use the embodiment of the present invention 1 gained plaster, once a day, each subsides wears 12 hours, and cervical region and right arm scapular region respectively paste one, within 10 days, are a course for the treatment of.Use 10 days, nighttime sleep has clear improvement, and can fall asleep.Use 20 days, both hands have obvious strength high, and mental attitude is taken on a new look to some extent, and pain symptom alleviates.Use 30 days, pain obviously alleviates, and mental restoration is good, and vision is also recovered to some extent.Use 50 days, other malaise symptoms disappear substantially, and patient's self-induction is fully recovered.
Embodiment 2 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 18 parts, Fructus Chaenomelis 10 parts, Radix Salviae Miltiorrhizae 17 parts, Rhizoma Et Radix Notopterygii 10 parts, 10 parts, Rhizoma Curcumae Longae, Bungarus fasciatus 13 parts, Herba Pyrolae 15 parts, Radix Clematidis 10 parts, seven lis of pellets 10 parts, Rhizoma Dioscoreae Nipponicae 9 parts.
The preparation method of the plaster of above-mentioned treatment cervical muscle myelopathy, step is:
1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and leaves standstill 20 days, filtration, obtains filtrate and filtering residue is for subsequent use;
2. by step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolae, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 40 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 10 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 80 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 15g to spread upon in adhesive plaster or other substrate, make plaster.
Embodiment 3 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 13 parts, Fructus Chaenomelis 3 parts, Radix Salviae Miltiorrhizae 13 parts, Rhizoma Et Radix Notopterygii 7 parts, 5 parts, Rhizoma Curcumae Longae, Bungarus fasciatus 10 parts, Herba Pyrolae 10 parts, Radix Clematidis 5 parts, seven lis of pellets 6 parts, Rhizoma Dioscoreae Nipponicae 6 parts.
The preparation method of the plaster of above-mentioned treatment cervical muscle myelopathy, step is:
1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and leaves standstill 13 days, filtration, obtains filtrate and filtering residue is for subsequent use;
2. by step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolae, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 25 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 7 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 65 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 8g to spread upon in adhesive plaster or other substrate, make plaster.
Typical case two field XX, female, 35 years old, Weifang, Shandong personage, the office worker of certain foreign enterprise.Long-term facing to computer work, one day almost little motion, nearly all facing to computer, during last summer, conscious left side neck root, shoulder and left upper arm pain, and extremity have slight feeling of numbness, originally do not take notice of, but before 1 month, there is urgent micturition in patient, frequent micturition, the symptom of constipation, household sees that the aggravation of its disease just goes to hospital to check, check and find patient's Wry Neck, cervical region is tilted to the right limited, when cervical region rotates to the left, the pain increased, cervical region with do scapula position and all have obvious tenderness sense, the slight lateral bending of X sheet display cervical flexure, be diagnosed as: cervical muscle myelopathy, doctor just suggestion uses embodiment 3 gained plaster.
Use the embodiment of the present invention 3 gained plaster, once a day, each subsides wears 12 hours, and cervical region and scapular region respectively paste one, within 10 days, are a course for the treatment of.Use 5 days, paste and wear the sensation that there is heating at position, feel well.Use 20 days, pain alleviates.Use 30 days, when noting posture and rest, substantially can avoid the generation of cervical pain symptom, omoplate place pain disappears completely, and cervical region can swing comparatively normally, and defecation is normal, and had no side effect between the operating period generation.
Embodiment 4 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 16 parts, Fructus Chaenomelis 7 parts, Radix Salviae Miltiorrhizae 15 parts, Rhizoma Et Radix Notopterygii 9 parts, 8 parts, Rhizoma Curcumae Longae, Bungarus fasciatus 12 parts, Herba Pyrolae 12 parts, Radix Clematidis 8 parts, seven lis of pellets 9 parts, Rhizoma Dioscoreae Nipponicae 8 parts.
The preparation method of the plaster of above-mentioned treatment cervical muscle myelopathy, step is:
1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and leaves standstill 18 days, filtration, obtains filtrate and filtering residue is for subsequent use;
2. by step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolae, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 35 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 9 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 75 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 13g to spread upon in adhesive plaster or other substrate, make plaster.
Typical case three grandson XX, man, 40 years old, Jinan, people from Shandong personage, the workman of certain factory.Before 1 half a year, sensation neck descendants rises suddenly, and right side numbness of lower limbs, pain, think it is that work is tired out at the beginning, also do not take notice of very much, but occurred that both upper extremities is numb in the time of nearest half a year, neck aches is severe.Patient's fearing very at that time, checks to Jinan large hospital under the accompanying of layman, checks and finds patient's restriction of neck motion, the pain increased in layback, cervical region tenderness is obvious, is diagnosed as: cervical muscle myelopathy, brings into use the embodiment of the present invention 4 gained plaster under the suggestion of doctor.
Use the embodiment of the present invention 4 gained plaster, once a day, each subsides wears 12 hours in cervical pain place, within 10 days, is a course for the treatment of.Use 10 days, pain is obviously alleviated, and numb limbs and tense tendons sense makes moderate progress.Use 20 days, pain disappears substantially, and feeling of numbness is obviously alleviated, and has strength on foot.Continue use 10 days, patient's self-induction is fully recovered.
Embodiment 5 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 15 parts, Fructus Chaenomelis 5 parts, Radix Salviae Miltiorrhizae 14 parts, Rhizoma Et Radix Notopterygii 8 parts, 6 parts, Rhizoma Curcumae Longae, Bungarus fasciatus 11 parts, Herba Pyrolae 11 parts, Radix Clematidis 7 parts, seven lis of pellets 8 parts, Rhizoma Dioscoreae Nipponicae 7 parts.
The preparation method of the plaster of above-mentioned treatment cervical muscle myelopathy, step is:
1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and leaves standstill 15 days, filtration, obtains filtrate and filtering residue is for subsequent use;
2. by step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolae, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 30 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 8 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 70 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 10g to spread upon in adhesive plaster or other substrate, make plaster.
Experimental example is in order to verify the curative effect of the present invention to cervical muscle myelopathy, and chosen two or more person 100 people of cervical muscle myelopathy symptom, the mean age is 40 years old, two groups are divided into according to the state of an illness, experimental group and matched group, often organize 50 people, basically identical to ensure two groups of situations.Experimental group uses embodiment 5 gained plaster, once a day, each subsides wear 12 hours, it within 10 days, is a course for the treatment of, matched group uses the Chinese medicine of other oral medication cervical muscle myelopathys, observes 30 days time limits, first within 1 day, comprehensively checks the symptom of patient before experiment, regularly check inquiry patient body situation and impression during experiment, and make a record.
1, carry out record to the curative effect of two groups of medicines, result is as following table 1.(criterion, effectively: the malaise symptoms caused by cervical muscle myelopathy has clear improvement; Invalid: the malaise symptoms caused by cervical muscle myelopathy is unchanged.）
Table 1:
Analyze: as can be seen from Table 1, the present invention is 99% to the effective percentage of cervical muscle myelopathy, exceeds matched group 11%, Be very effective.
2, carry out record to two groups of patient's applied mental changes, result is as following table 2.
Table 2:
Analyze: as can be seen from Table 2, medicament mode of the present invention is more easily approved by patient, and major part represents per capita, Long-term taking medicine easily causes mental pressure, and obviously can affect appetite, external used medicine is favored by more people on therapeutic modality, is also more easy to accept and adhere to long-term treatment.Through finding out the analysis of many group experimental datas, plaster of the present invention is obvious for cervical muscle myelopathy curative effect, and total effective rate is up to 96%, and without any side effects, can reach the effect of pain-alleviating and network vessel-freeing comparatively rapidly.On therapeutic modality, the present invention is also easier to, by patient's recognition and acceptance, to lay a good foundation for later treatment.

Claims (2)

1. treat a plaster for cervical muscle myelopathy, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Pheropsophus jessoensis Mor. 13 parts, Fructus Chaenomelis 3 parts, Radix Salviae Miltiorrhizae 13 parts, Rhizoma Et Radix Notopterygii 7 parts, 5 parts, Rhizoma Curcumae Longae, Bungarus fasciatus 10 parts, Herba Pyrolae 10 parts, Radix Clematidis 5 parts, seven lis of pellets 6 parts, Rhizoma Dioscoreae Nipponicae 6 parts.
2. treat the preparation method of the plaster of cervical muscle myelopathy, it is characterized in that,
1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and leaves standstill 13 days, filtration, obtains filtrate and filtering residue is for subsequent use;
2. by step 1. in gained filtering residue add water, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolae, and intense fire is fried open, and fire of larding speech with literary allusions is decocted slowly, decocts to 25 minutes, filters to get filtrate;
3. by step 1. in gained filtrate and step 2. in gained filtrate mix, standing 7 hours, filtration, filtrate is purified again by the way of distillation, obtains distillate for subsequent use;
4. vegetable oil and rosin heating is added in pot, do not stop to stir, to be mixed evenly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 65 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, get 8g to spread upon in adhesive plaster or other substrate, make plaster.
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