CN104383383A - Chinese medicinal wine for promoting healing of bone fracture and preparation method thereof - Google Patents
Chinese medicinal wine for promoting healing of bone fracture and preparation method thereof Download PDFInfo
- Publication number
- CN104383383A CN104383383A CN201410752791.3A CN201410752791A CN104383383A CN 104383383 A CN104383383 A CN 104383383A CN 201410752791 A CN201410752791 A CN 201410752791A CN 104383383 A CN104383383 A CN 104383383A
- Authority
- CN
- China
- Prior art keywords
- liquor
- chinese
- chinese medicinal
- bone injury
- traditional chinese
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/45—Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
- A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a Chinese medicinal wine for promoting the healing of a bone fracture and a preparation method thereof. The Chinese medicinal wine is mainly prepared from the following raw materials in parts by weight: 3-9 parts of grewia lantsangensis hu, 3-6 parts of gaultheria yunnanensis, 4-8 parts of Korean raspberry roots, 6-12 parts of glabrous greenbrier rhizome, 6-9 parts of Chinese tinospora stems, 6-12 parts of shortlobe ligusticum roots and an appropriate amount of white wine. The Chinese medicinal wine disclosed by the invention is low in treatment cost and short in healing time, can be used for relieving the pain of a patient, is safe and effective and can not cause side effects.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of Traditional Chinese medicinal liquor promoting bone injury healing and preparation method thereof.
Background technology
It is injured because of external force that bone injury generally refers to bone, and bone injury is changeable, if treat not in time, gently then affects ability to act, heavy then can cause paralysis, even threat to life.According to the concrete symptom that knee swells and ache, patient tentatively can make deduction.If wound causes, may be Secondary cases synovitis, even hydrarthrosis; If be not subject to exterior trauma, old people at an early age bone was subject to wound, and with advancing age, joint degenerative lesion is serious, also can cause synovitis, osteoarthritis etc., cause bone to swell and ache; If never cross bone trauma history, it may be the omen of rheumatism, rheumatoid, gout or osteoarthritis.The main cause that fracture occurs mainly contains three kinds of situations: 1. direct violence.Violence directly acts on a certain position of skeleton and causes this fracture, then often make injury fracture, often with soft tissue destruction in various degree, as wheel clashes into shank, in shock place generation fracture of shafts of tibia and fibula.2. indirect violence.By longitudinally conduction during indirect violence effect, leverage or twisting action make to fracture at a distance, as fall from eminence foot land time, trunk because gravity relation is sharply to pre-buckling, breast lumbar spine intersection vertebral body by jack knife power effect and there is compression fracture conduction.3. accumulation property strain.For a long time, repeatedly, slight direct or indirect damage can cause limbs a certain specific part fracture, easily causes second as marched at a distance, 1/3 shaft fracture under three metatarsals and fibula.
The complication of bone injury: 1. suffer a shock.2. fat embolism syndrome.3. important internal organs damage: 1. liver, rupture of spleen.2. breast injury of lung.2. the dirty and injury of urethra of wing, damage of intestines.4. important damaging surrounding tissue: 1. important blood vessels damage.2. peripheral nerve injury.3. spinal cord injury.5. osteofascial compartment syndrome: a series of early stage syndrome that in the bone fascial bursa namely formed by bone, interosseous membrane, intermuscular septum and deep fascia, muscle and nerve produce because of acute ischemia.See at most forearm palmar and shank, often by the hematoma of damage fracture and tissue edema make its indoor content object long-pending increase or dress outside tension, local compression makes bone fascial bursa volume reduce and to cause in bone fascial bursa caused by pressure increases.The General Symptoms of bone injury: 1. heating paresthesia: fracture has a large amount of internal hemorrhage, during absorption of hematoma, body temperature slightly raises, and when open fracture body temperature raises, should consider the possibility infected.2. produce shock symptom: for multiple fracture, fracture of pelvis, Fracture of femur, spinal fracture and serious open bone.Patient Chang Yin widely soft tissue injury, bleed profusely, have an intense pain or concurrent visceral injury etc. and cause shock., after fracture, there is abnormal activity in local symptom: 1. abnormal movement symptom: the immobile position of normal condition lower limb body.2. lopsided symptom: fracture segment displacement can make suffering limb profile change, main manifestations is for shortening.3. bony crepitus or bone rubbing feeling symptom: after fracture, during two fracture end phase mutual friction, can produce bone and get rid of sound or bone rubbing feeling.
Application publication number CN 102988687 A(application number 201210489201.3) Chinese patent literature disclose a kind of medicated wine promoting bone injury healing, be made up of the component of following percentage by weight: 10-15 part Os Draconis, 3-6 part Poria, 2-5 part Rhizoma Dioscoreae, 20-40 part Radix Achyranthis Bidentatae, 1-5 part Radix Dipsaci and 3-6 part Cortex Eucommiae.Application publication number CN 102988688 A(apply for 201210489474.8) Chinese patent literature disclose a kind of preparation method promoting the medicated wine of bone injury healing, it comprises the following steps: (1) respectively Os Draconis, Poria, Rhizoma Dioscoreae, Radix Achyranthis Bidentatae, Radix Dipsaci and the Cortex Eucommiae grinds, and crosses 60 mesh sieves; (2) by grind 10-15 part Os Draconis, 3-6 part Poria, 2-5 part Rhizoma Dioscoreae, 20-40 part Radix Achyranthis Bidentatae, 1-5 part Radix Dipsaci and 3-6 part Cortex Eucommiae mix homogeneously; (3) with the w/v of 1:5, the mixture of (2) is soaked in rice wine, within every three days, stirs once, continue immersion 20 days, filter medicinal residues, get product.Application publication number CN 103705700 A(application number 201310755444.1) Chinese patent literature disclose a kind of externally-used embrocation promoting bone injury healing, be characterized in, it comprises the crude drug of following weight component, Cortex Acanthopancis, Concha Ostreae, Sanguis Draxonis, catechu, Cortex Mori, Myrrha, Olibanum, Endoconcha Sepiae, Moschus are a little, its preparation method is: enter in iron pan by Cortex Acanthopancis, Concha Ostreae, Sanguis Draxonis, catechu, Cortex Mori, Myrrha, Olibanum, Endoconcha Sepiae, remove slag after at a simmerization, decoct through high temperature again, second time removes slag, and it is a little that decoction liquor adds Moschus in the used time.
For the treatment of bone injury disease, doctor trained in Western medicine many employings operative treatment, and operation will damage the blood fortune of fracture, lowers self repair ability of fracture, closed fracture is become open fracture, band serves complication and adverse consequences.In addition, relying on operation to carry out reduction needs longer treatment time, and costly, and patient suffering is more.Traditional Chinese medical bone-fracture treating bone fracture, adopt No operation traditional method expectant treatment, based on medicine for external use, treatment time is partially long.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide a kind of Traditional Chinese medicinal liquor promoting bone injury healing and preparation method thereof.Medical expense of the present invention is low, can reduce patient suffering, healing time is short, safe and effective, have no side effect.
Technical scheme of the present invention is:
Promote the Traditional Chinese medicinal liquor of bone injury healing, take off the primary raw material medicine stating weight proportion and be prepared from: prairie fire rope 3-9, Caulis et folium gaultheriae yunnanensis 3-6, Radix rubi coreani 4-8, Rhizoma Smilacis Glabrae 6-12, Herba Lycopodii 6-9, Radix Ligustici Brachylobi 6-12, Chinese liquor is appropriate.
Promote the Traditional Chinese medicinal liquor of bone injury healing, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: prairie fire rope 4-8, Caulis et folium gaultheriae yunnanensis 4-5, Radix rubi coreani 5-7, Rhizoma Smilacis Glabrae 7-9, Herba Lycopodii 7-8, Radix Ligustici Brachylobi 8-10, Chinese liquor is appropriate.
Promote the Traditional Chinese medicinal liquor of bone injury healing, the scheme be more preferably is, take off the primary raw material medicine stating weight proportion and be prepared from: prairie fire rope 6, Caulis et folium gaultheriae yunnanensis 4.5, Radix rubi coreani 6, Rhizoma Smilacis Glabrae 8, Herba Lycopodii 7.5, Radix Ligustici Brachylobi 9, Chinese liquor is appropriate.
The preparation method of the Traditional Chinese medicinal liquor of above-mentioned promotion bone injury healing is:
(1) each Chinese crude drug is cleaned respectively, dried in the shade, be ground into fine powder, cross 70-110 mesh sieve;
(2) step (1) gained fine powder is fully mixed, pack with clean gauze, tighten bag mouth, put into ceramic vessel or dark glass drinking vessel, then add Chinese liquor, the amount of Chinese liquor is 7-12 times of 6 taste Chinese crude drug gross weights, the number of degrees of Chinese liquor are 50-60 degree, be placed on the sealing of sombre lucifuge place to soak, every day stirs once, soaks 20-30 days, filter medicinal residues, wine liquid leaves standstill 5-10 hour, and filter, the wine liquid after filtration is stored in bottle.
Preferably be in step (1), cross 80-100 mesh sieve.
Preferably be in step (2), the amount of Chinese liquor is 8-10 times of 6 taste Chinese crude drug gross weights.
Preferably be in step (2), the number of degrees of Chinese liquor are 52-56 degree.
Preferably be in step (2), soak 22-28 days.
Preferably be that in step (2), wine liquid leaves standstill 6-9 hour.
Be more preferably, in step (1), cross 90 mesh sieves.
Be more preferably, in step (2), the amount of Chinese liquor is 9 times of 6 taste Chinese crude drug gross weights.
Be more preferably, in step (2), the number of degrees of Chinese liquor are 53 degree.
Be more preferably, soak 25 days in step (2).
Be more preferably, in step (2), wine liquid leaves standstill 8 hours.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Prairie fire rope: base is former: Tiliaceae prairie fire rope, is used as medicine with root endothelium.The property of medicine: puckery, micro-hardship, cool.Function cures mainly: hemostasis, synthetism, granulation promoting, removing toxic substances.The damage of main traumatic hemorrhage, weapons, fracture, furuncle redness.
Caulis et folium gaultheriae yunnanensis: base is former: be Herb or the root of ericad Caulis et folium gaultheriae yunnanensis.Chemical analysis: Caulis et folium gaultheriae yunnanensis leaf is containing volatile oil 0.5% ~ 0.8%.Wherein main component is methyl salicylate.The property of medicine: pungent, temperature.Return lung, liver, kidney channel.Function cures mainly: expelling wind and removing dampness, dispersing cold for relieving pain, promoting blood circulation to remove obstruction in the collateral, preventing phlegm from forming and stopping coughing.Main air pain of dampness syndrome, cold syndrome of the stomach pain, traumatic injury, cough ant phlegm.
Radix rubi coreani: base is former: be the root of rosaceous plant rubus coreanus.The property of medicine: bitter, puckery, flat, nontoxic.Return liver, kidney channel.Function cures mainly: promoting blood circulation and hemostasis, expelling wind and removing dampness.Main traumatic injury, fracture, menoxenia, spits blood, epistaxis, rheumatic arthralgia, edema, dysuria, scrofula.
Rhizoma Smilacis Glabrae: base is former: be the rhizome of Liliaceae smilax plant smilacis glabra.Composition: rhizome is containing volatile oil: 49 kinds of compositions such as n-hexadecanoic methyl ester; Phenolic acids: 3-0-caffeoyl shikimic acid, ferulic acid; Steroidal saponin, flavonoid glycoside etc.The property of medicine: sweet, light, flat.Return liver,kidney,spleen, stomach warp.Function cures mainly: removing damp-heat, lets out turbid removing toxic substances, easing joint movement.Cure mainly syphilis, stranguria with turbid discharge, have loose bowels, muscles and bones spasm and pain, beriberi, carbuncle, skin ulcer tinea, scrofula, goiter and mercurialism.
Herba Lycopodii: base is former: be the stem of menispermaceae plant Tinospora sinensis.The property of medicine: micro-hardship, cool.Return Liver Channel.Function cures mainly: wind-expelling pain-stopping, relaxing muscles and tendons and activating QI and blood in the collateral.Main air pain of dampness syndrome, lumbar muscle strain, traumatic injury.
Radix Ligustici Brachylobi: base is former: be the root of samphire ring Radix Peucedani.The property of medicine: pungent, micro-sweet, tepor.Return lung, bladder, liver, spleen channel.Function cures mainly: deliver, dispel the wind, win wet, pain relieving.Main anemofrigid cold, flu folder are wet, headache, giddy, cold-damp is suffered from abdominal pain, have loose bowels, rheumatic arthralgia, spasm of the limbs, tetanus, conjunctival congestion, skin infection, hernia abdominal mass, scabies, rubella.
Chinese liquor: have another name called liquor, white spirit is the conventional beverage wine of China.Record according to Compendium of Material Medica: " also, original when unit, its method heavy wine and grain enter rice steamer (referring to steamer) to liquor Fei Gufa, steam and make on gas, hold drip dew with device." Chinese liquor is except drinking; also have following function: (1) prevention cardiovascular diseases: a small amount of drinking white spirit; the high density lipoprotein in blood of human body can be increased; and high density lipoprotein can will can cause the low density lipoprotein, LDL etc. of cardiovascular diseases; shift from blood vessel and coronary artery; thus just effectively can reduce coronary artery inner cholesterol deposition, the effect of prevention cardiovascular diseases.(2) allaying tiredness and anxiety: a small amount of drinking white spirit, by the effect of ethanol to brain and nervus centralis, can play allaying tiredness, lax neural effect.(3) appetite-stimulating indigestion-relieving: while dining, drink a small amount of Chinese liquor, can appetite stimulator, promotes the digestion of food, certainly too much drinks and can cause gastrointestinal upset.(4) cold is driven away: Chinese liquor contains a large amount of heats, and after drinking human body, these heats can be absorbed by the body rapidly.(5) enhance metabolism: Chinese liquor is for containing more alcoholic content, and heat is higher, thus can promote the blood circulation of human body, plays necessarily optimum stimulation to whole skin, thus the effect promoting human metabolism can also be reached.This optimum stimulation can also act on nerve conduction in Europe, thus can have necessarily good through effect for systemic blood.(6) relaxing muscles and tendons to promote blood circulation: Chinese liquor has effect of channels sootheing and network vessel quickening, activating blood circulation to dissipate blood stasis.
The Traditional Chinese medicinal liquor of promotion bone injury healing provided by the invention is safe and effective, has no side effect.In addition, excellent results of the present invention also shows:
1, medical expense is low, can alleviate the financial burden of patient;
2, healing time is short, can reduce patient suffering, improves the quality of life of patient;
3, there is the effects such as channels sootheing and network vessel quickening, activating blood circulation to dissipate blood stasis, bone-setting pain stopping, heat-clearing and toxic substances removing, easing joint movement, can affected part be urged
Peripheral vasodilation, improves local blood circulation, promotes growth of spur, accelerates bone injury healing;
4, preparation method is simple.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1promote the Traditional Chinese medicinal liquor of bone injury healing, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): 3 parts, prairie fire rope, Caulis et folium gaultheriae yunnanensis 3 parts, Radix rubi coreani 4 parts, Rhizoma Smilacis Glabrae 6 parts, Herba Lycopodii 6 parts, Radix Ligustici Brachylobi 6 parts, Chinese liquor is appropriate.
The preparation method of the Traditional Chinese medicinal liquor of above-mentioned promotion bone injury healing is:
(1) each Chinese crude drug is cleaned respectively, dried in the shade, be ground into fine powder, cross 70 mesh sieves;
(2) step (1) gained fine powder is fully mixed, pack with clean gauze, tighten bag mouth, put into dark glass drinking vessel, then add Chinese liquor, the amount of Chinese liquor is 7 times of 6 taste Chinese crude drug gross weights, the number of degrees of Chinese liquor are 50 degree, be placed on the sealing of sombre lucifuge place to soak, every day stirs once, soaks 20 days, filter medicinal residues, wine liquid leaves standstill 5 hours, and filter, the wine liquid after filtration is stored in bottle.
The present invention promotes the using method of the Traditional Chinese medicinal liquor of bone injury healing: for oral administration, every day twice, each 1-2 two; Also can external, dip medicinal liquid with rayon balls and embrocate affected part, every day embrocates 1-3 time.
embodiment 2promote the Traditional Chinese medicinal liquor of bone injury healing, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): 9 parts, prairie fire rope, Caulis et folium gaultheriae yunnanensis 6 parts, Radix rubi coreani 8 parts, Rhizoma Smilacis Glabrae 12 parts, Herba Lycopodii 9 parts, Radix Ligustici Brachylobi 12 parts, Chinese liquor is appropriate.
The preparation method of the Traditional Chinese medicinal liquor of above-mentioned promotion bone injury healing is:
(1) each Chinese crude drug is cleaned respectively, dried in the shade, be ground into fine powder, cross 110 mesh sieves;
(2) step (1) gained fine powder is fully mixed, pack with clean gauze, tighten bag mouth, put into ceramic vessel or dark glass drinking vessel, then add Chinese liquor, the amount of Chinese liquor is 12 times of 6 taste Chinese crude drug gross weights, the number of degrees of Chinese liquor are 60 degree, be placed on the sealing of sombre lucifuge place to soak, every day stirs once, soaks 30 days, filter medicinal residues, wine liquid leaves standstill 10 hours, and filter, the wine liquid after filtration is stored in bottle.
model case one:xu XX, female, 52 years old.Patient was knocked down before 12 days by bike, and two wrist is injured, and deformity swells and ache.Examine as bilateral radius comminuted fractures of distal.Use the present invention to promote the Traditional Chinese medicinal liquor of bone injury healing, dip medicinal liquid with rayon balls and embrocate affected part, embrocate 2 every day.After 5 days, left wrist is obviously subsided a swelling, and pain subtracts greatly, can take food with soupspoon.Find in the 10th day photo, bilateral radius all has obvious callus to occur.After 20 days, union of fracture, left hand can be taken care of oneself substantially.
embodiment 3promote the Traditional Chinese medicinal liquor of bone injury healing, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): 4 parts, prairie fire rope, Caulis et folium gaultheriae yunnanensis 4 parts, Radix rubi coreani 5 parts, Rhizoma Smilacis Glabrae 7 parts, Herba Lycopodii 7 parts, Radix Ligustici Brachylobi 8 parts, Chinese liquor is appropriate.
The preparation method of the Traditional Chinese medicinal liquor of above-mentioned promotion bone injury healing is:
(1) each Chinese crude drug is cleaned respectively, dried in the shade, be ground into fine powder, cross 80 mesh sieves;
(2) step (1) gained fine powder is fully mixed, pack with clean gauze, tighten bag mouth, put into ceramic vessel or dark glass drinking vessel, then add Chinese liquor, the amount of Chinese liquor is 8 times of 6 taste Chinese crude drug gross weights, the number of degrees of Chinese liquor are 52 degree, be placed on the sealing of sombre lucifuge place to soak, every day stirs once, soaks 22 days, filter medicinal residues, wine liquid leaves standstill 6 hours, and filter, the wine liquid after filtration is stored in bottle.
model case two:horse XX, female, 40 years old.Patient accidentally sprained left ankle pain and is admitted to hospital before 1 day.X sheet checks: left side fibula external malleolus and tibia back ankle fracture.CT examination: left side fibula external malleolus and tibia back ankle fracture, back ankle fracture feeds through to internal malleolus.Use the Drug therapys such as GUZHE CUOSHANG JIAONANG, effect is undesirable.Use the present embodiment gained to promote the Traditional Chinese medicinal liquor of bone injury healing, dip medicinal liquid with rayon balls and embrocate affected part, embrocate 3 every day.After 10 days, fracture end healing is good.After 15 days, patient makes film further consultation, and fracture heals completely, and function is recovered completely, and walking is freely, painless.
embodiment 4promote the Traditional Chinese medicinal liquor of bone injury healing, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): 8 parts, prairie fire rope, Caulis et folium gaultheriae yunnanensis 5 parts, Radix rubi coreani 7 parts, Rhizoma Smilacis Glabrae 9 parts, Herba Lycopodii 8 parts, Radix Ligustici Brachylobi 10 parts, Chinese liquor is appropriate.
The preparation method of the Traditional Chinese medicinal liquor of above-mentioned promotion bone injury healing is:
(1) each Chinese crude drug is cleaned respectively, dried in the shade, be ground into fine powder, cross 100 mesh sieves;
(2) step (1) gained fine powder is fully mixed, pack with clean gauze, tighten bag mouth, put into ceramic vessel or dark glass drinking vessel, then add Chinese liquor, the amount of Chinese liquor is 10 times of 6 taste Chinese crude drug gross weights, the number of degrees of Chinese liquor are 56 degree, be placed on the sealing of sombre lucifuge place to soak, every day stirs once, soaks 28 days, filter medicinal residues, wine liquid leaves standstill 9 hours, and filter, the wine liquid after filtration is stored in bottle.
model case three:zhao XX, female, 60 years old.Accidentally throw from stair, cause " under right femoral shaft 1/3 comminuted fracture ", give " right femoral shaft steel plate screw internal fixation " postoperative six months at local hospital, because its right lower limb affected part pain when moving or have a fling at heavy burden is obvious, check of then making film.X sheet display fracture end gap exists, and sclerotin slightly loosens, fracture indolence.Doctor ordered patient is in lean on to turn to continue to take exercise and observes, and it is oral with the Chinese patent medicine of replenishing the calcium to have opened some relaxing muscles and tendons to promote blood circulation.Thereafter because symptom has no improvement always, patient considers that the reasons such as age refuse operative treatment again, and by the agency of comes here and wishes traditional Chinese medical science expectant treatment.Before check: X-ray film shows right femoral shaft hypomere and fractures helically comminuted, and fracture line is clear, the broken ends of fractured bone is without obvious callus formation, and bone density declines, and is defined as bone does not connect.
Use the present embodiment gained to promote the Traditional Chinese medicinal liquor of bone injury healing, dip medicinal liquid with rayon balls and embrocate affected part, embrocate 3 every day.Use after 10 days, carry out check film making, X-ray film shows that fracture line disappears, and has seriality callus to pass through fracture line.The right lower limb of patient's private prosecution not pain substantially, dared slight heavy burden, the healths such as sleep of having a meal are very good.After 20 days, patient has gone crutches to lean on walking stick walking, and health is good.Follow up a case by regular visits to old man's health mental status good, do not needed on foot to borrow any external force level road continuous walking to feel without discomfort half an hour, because patient is older, patient determines not remove internal fixtion.
embodiment 5promote the Traditional Chinese medicinal liquor of bone injury healing, the primary raw material medicine getting following weight parts is prepared from (every part is 50g): 6 parts, prairie fire rope, Caulis et folium gaultheriae yunnanensis 4.5 parts, Radix rubi coreani 6 parts, Rhizoma Smilacis Glabrae 8 parts, Herba Lycopodii 7.5 parts, Radix Ligustici Brachylobi 9 parts, Chinese liquor is appropriate.
The preparation method of the Traditional Chinese medicinal liquor of above-mentioned promotion bone injury healing is:
(1) each Chinese crude drug is cleaned respectively, dried in the shade, be ground into fine powder, cross 90 mesh sieves;
(2) step (1) gained fine powder is fully mixed, pack with clean gauze, tighten bag mouth, put into ceramic vessel or dark glass drinking vessel, then add Chinese liquor, the amount of Chinese liquor is 9 times of 6 taste Chinese crude drug gross weights, the number of degrees of Chinese liquor are 53 degree, be placed on the sealing of sombre lucifuge place to soak, every day stirs once, soaks 25 days, filter medicinal residues, wine liquid leaves standstill 8 hours, and filter, the wine liquid after filtration is stored in bottle.
test example 1promote the clinical practice of Traditional Chinese medicinal liquor of bone injury healing: in July, 2010 in December ,-2012, screen 248 routine patient with bone fracture in 5 hospitals, wherein male 148 example, women 100 example, oldest 70 years old, minimum 15 years old of age, 42 years old mean age, course of disease 1-10 month, average course of disease 3 months.Be divided into two groups at random, experimental group and matched group (often organizing 124 examples).Experimental group women 50 example, male 74 example, age 15-70 year, 42 years old mean age, course of disease 1-10 month, average course of disease 3 months.Matched group women 50 example, male 74 example, age 15-70 year, 42 years old mean age, course of disease 1-10 month, average course of disease 3 months.Between two groups of patients, the aspect such as sex, age, course of disease compares, and no significant difference (P > 0.05), has comparability.Experimental group uses embodiment 5 products obtained therefrom, using method: for oral administration, every day twice, each 1-2 two; Also can external, dip medicinal liquid with rayon balls and embrocate affected part, every day embrocates 1-3 time.Matched group uses the conventional medicine (as GUZHE CUOSHANG JIAONANG, Osteoking, bone setting tablet, Anisodus carniolicoides C.Y.Wu et C.Chen, ZHENGGU ZIJINDAN etc.) promoting bone injury healing.Curative effect situation criterion: recovery from illness: symptom, sign, x-ray take the photograph sheet and other checks that all recovery is normal; Effective: symptom, sign, x-ray are taken the photograph sheet and all taken an evident turn for the better; Take a turn for the better: symptom, sign, x-ray are taken the photograph sheet and alleviated; Invalid: symptom, sign, x-ray are taken the photograph sheet and be not improved.Total effectively comprise recovery from illness and effective.Treat result after 15 days as shown in table 1.
Table 1: take embodiment 5 product patient with bone fracture therapeutic outcome
As can be seen from Table 1, the experimental group total effective rate of the Traditional Chinese medicinal liquor of bone injury healing reaches 98.39% to use embodiment 5 gained to promote.And matched group has nearly 14 people invalid, total effective rate only has 66.13%.Test shows, the successful of experimental group is better than matched group.
The present invention selects prairie fire rope, Caulis et folium gaultheriae yunnanensis, Radix rubi coreani, Rhizoma Smilacis Glabrae, Herba Lycopodii and Radix Ligustici Brachylobi as crude drug, with soaking in Chinese liquor, and the obtained Traditional Chinese medicinal liquor promoting bone injury healing.The hemostasis of prairie fire rope, synthetism, granulation promoting, removing toxic substances in side.Caulis et folium gaultheriae yunnanensis expelling wind and removing dampness, dispersing cold for relieving pain, promoting blood circulation to remove obstruction in the collateral, preventing phlegm from forming and stopping coughing.Radix rubi coreani promoting blood circulation and hemostasis, expelling wind and removing dampness.Rhizoma Smilacis Glabrae removing damp-heat, lets out turbid removing toxic substances, easing joint movement.Herba Lycopodii wind-expelling pain-stopping, relaxing muscles and tendons and activating QI and blood in the collateral.Radix Ligustici Brachylobi is delivered, dispel the wind, win wet, pain relieving.Chinese liquor has effect of channels sootheing and network vessel quickening, activating blood circulation to dissipate blood stasis.All medicines share, and have the effects such as channels sootheing and network vessel quickening, activating blood circulation to dissipate blood stasis, bone-setting pain stopping, heat-clearing and toxic substances removing, easing joint movement, can urge affected part peripheral vasodilation, improve local blood circulation, promote growth of spur, accelerate bone injury healing.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (9)
1. promote the Traditional Chinese medicinal liquor of bone injury healing, it is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: prairie fire rope 3-9, Caulis et folium gaultheriae yunnanensis 3-6, Radix rubi coreani 4-8, Rhizoma Smilacis Glabrae 6-12, Herba Lycopodii 6-9, Radix Ligustici Brachylobi 6-12, Chinese liquor is appropriate.
2. the Traditional Chinese medicinal liquor of promotion bone injury healing according to claim 1, is characterized in that, takes off the primary raw material medicine stating weight proportion and is prepared from: prairie fire rope 4-8, Caulis et folium gaultheriae yunnanensis 4-5, Radix rubi coreani 5-7, Rhizoma Smilacis Glabrae 7-9, Herba Lycopodii 7-8, Radix Ligustici Brachylobi 8-10, Chinese liquor is appropriate.
3. the Traditional Chinese medicinal liquor of promotion bone injury healing according to claim 1, is characterized in that, take off the primary raw material medicine stating weight proportion and be prepared from: prairie fire rope 6, Caulis et folium gaultheriae yunnanensis 4.5, Radix rubi coreani 6, Rhizoma Smilacis Glabrae 8, Herba Lycopodii 7.5, Radix Ligustici Brachylobi 9, Chinese liquor is appropriate.
4., according to the preparation method of the Traditional Chinese medicinal liquor of the arbitrary described promotion bone injury healing of claim 1-3, it is characterized in that, step is as follows:
(1) each Chinese crude drug is cleaned respectively, dried in the shade, be ground into fine powder, cross 70-110 mesh sieve;
(2) step (1) gained fine powder is fully mixed, pack with clean gauze, tighten bag mouth, put into ceramic vessel or dark glass drinking vessel, then add Chinese liquor, the amount of Chinese liquor is 7-12 times of 6 taste Chinese crude drug gross weights, the number of degrees of Chinese liquor are 50-60 degree, be placed on the sealing of sombre lucifuge place to soak, every day stirs once, soaks 20-30 days, filter medicinal residues, wine liquid leaves standstill 5-10 hour, and filter, the wine liquid after filtration is stored in bottle.
5. the preparation method of the Traditional Chinese medicinal liquor of promotion bone injury healing according to claim 4, is characterized in that, crosses 80-100 mesh sieve (preferred mistake 90 mesh sieve) in step (1).
6. the preparation method of the Traditional Chinese medicinal liquor of promotion bone injury healing according to claim 4, is characterized in that, in step (2), the amount of Chinese liquor is 8-10 times (amount of preferred Chinese liquor is 9 times of 6 taste Chinese crude drug gross weights) of 6 taste Chinese crude drug gross weights.
7. the preparation method of the Traditional Chinese medicinal liquor of promotion bone injury healing according to claim 4, is characterized in that, in step (2), the number of degrees of Chinese liquor are 52-56 degree (number of degrees of preferred Chinese liquor are 53 degree).
8. the preparation method of the Traditional Chinese medicinal liquor of promotion bone injury healing according to claim 4, is characterized in that, soaks 22-28 days (preferably soaking 25 days) in step (2).
9. the preparation method of the Traditional Chinese medicinal liquor of promotion bone injury healing according to claim 4, is characterized in that, in step (2), wine liquid leaves standstill 6-9 hour (preferred wine liquid leaves standstill 8 hours).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410752791.3A CN104383383A (en) | 2014-12-11 | 2014-12-11 | Chinese medicinal wine for promoting healing of bone fracture and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410752791.3A CN104383383A (en) | 2014-12-11 | 2014-12-11 | Chinese medicinal wine for promoting healing of bone fracture and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104383383A true CN104383383A (en) | 2015-03-04 |
Family
ID=52601407
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410752791.3A Pending CN104383383A (en) | 2014-12-11 | 2014-12-11 | Chinese medicinal wine for promoting healing of bone fracture and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104383383A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375584A (en) * | 2017-08-30 | 2017-11-24 | 靖西市金峰贸易有限公司 | A kind of medicinal liquor of set a broken bone |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103055232A (en) * | 2013-01-31 | 2013-04-24 | 任军强 | Medicine for treating rheumatoid bone diseases and preparation method thereof |
| KR20140045894A (en) * | 2012-10-09 | 2014-04-17 | 한국생명공학연구원 | A pharmaceutical composition for preventing or treating il-6-mediated disease, comprising extract, fraction, or compounds derived from ampelopsis brevipedunculata |
-
2014
- 2014-12-11 CN CN201410752791.3A patent/CN104383383A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20140045894A (en) * | 2012-10-09 | 2014-04-17 | 한국생명공학연구원 | A pharmaceutical composition for preventing or treating il-6-mediated disease, comprising extract, fraction, or compounds derived from ampelopsis brevipedunculata |
| CN103055232A (en) * | 2013-01-31 | 2013-04-24 | 任军强 | Medicine for treating rheumatoid bone diseases and preparation method thereof |
Non-Patent Citations (3)
| Title |
|---|
| 南京中医药大学: "《中药大辞典 下 第2版》", 31 March 2006, 上海科学技术出版社 * |
| 国家中医药管理局《中华本草》编委会: "《中华本草4》", 31 December 1999, 上海科学技术出版社 * |
| 李成林等: "复方穿山龙治疗膝骨关节炎35例疗效观察", 《实用中西医结合临床》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107375584A (en) * | 2017-08-30 | 2017-11-24 | 靖西市金峰贸易有限公司 | A kind of medicinal liquor of set a broken bone |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100423761C (en) | Chinese medicinal preparation for treating fracture, traumatic injury | |
| CN104147577B (en) | A kind of plaster for promoting growth of spur to treat fracture | |
| CN106492133A (en) | A kind of reunion of bone, blood circulation promoting and blood stasis dispelling, the Chinese medicine plaster of reducing swelling and alleviating pain and preparation method | |
| CN102908442B (en) | Composition for treating traumatic injuries and medicinal liquor thereof | |
| CN103861047A (en) | Traditional Chinese medicament for treating femoral shaft fractures and preparation method of traditional Chinese medicament | |
| CN104116889A (en) | Pill for treating low back pains and preparation method of pill | |
| CN111494596A (en) | External medicine for diminishing inflammation and relieving pain and preparation method thereof | |
| CN110227117A (en) | It is a kind of to treat osteoproliferation, pharmaceutical composition of lumbocrural pain and preparation method thereof | |
| CN103977367A (en) | Traditional Chinese medicament for treating qi-stagnation blood-aggregation type bedsore and preparation method thereof | |
| CN104383383A (en) | Chinese medicinal wine for promoting healing of bone fracture and preparation method thereof | |
| CN104523879A (en) | Medicinal wine with effect of treating bone fracture and preparation method | |
| CN104258077A (en) | Traditional Chinese medicine for treating fracture and preparation method thereof | |
| CN105168973B (en) | A kind of Chinese medicine for treating cervical and lumbar diseases | |
| CN109125544A (en) | A kind of external application bone-setting ointment and preparation method thereof | |
| CN107837375A (en) | A kind of saussurea involucrata Wind-dispelling ointment and preparation method thereof | |
| CN104398686A (en) | Traditional Chinese medicinal ointment for promoting fracture healing and preparation method | |
| CN105687542A (en) | Chinese herbal preparation for fracture aftertreatment and preparing method thereof | |
| CN104800804A (en) | Medicament for quickly and efficiently treating fracture and preparation method of medicament | |
| CN105362944A (en) | Traditional Chinese medicine ointment for treating orthopedics sprain and contusion | |
| CN104689183A (en) | Medicinal liquor with swelling eliminating and blood stasis dispersing functions and preparing method thereof | |
| CN105770070A (en) | Method for preparing orthopedic and traumatology astringency and hemostasis medicinal liquor | |
| CN105267411B (en) | A kind of pharmaceutical composition for treating fracture | |
| CN114470124A (en) | Plaster for treating femoral head necrosis and shoulder, neck, waist and leg pain and preparation method thereof | |
| CN104352843A (en) | Tendon-relaxing and collateral-activating preparation for bone injury prognosis and preparation method of tendon-relaxing and collateral-activating preparation | |
| CN110585290A (en) | Swelling eliminating patch for promoting blood circulation to arrest pain and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB02 | Change of applicant information |
Address after: Longshan road 033000 Shanxi city of Lvliang province Lishi District No. 633 Hualong District 4 Building 1-202 Applicant after: Li Xuecun Address before: 250000 No. 1 Zijinshan Road, Tianqiao District, Shandong, Ji'nan, China Applicant before: Li Xuecun |
|
| COR | Change of bibliographic data | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150304 |