CN110227117A - It is a kind of to treat osteoproliferation, pharmaceutical composition of lumbocrural pain and preparation method thereof - Google Patents

It is a kind of to treat osteoproliferation, pharmaceutical composition of lumbocrural pain and preparation method thereof Download PDF

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CN110227117A
CN110227117A CN201910678264.5A CN201910678264A CN110227117A CN 110227117 A CN110227117 A CN 110227117A CN 201910678264 A CN201910678264 A CN 201910678264A CN 110227117 A CN110227117 A CN 110227117A
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parts
root
pain
osteoproliferation
blood
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姜友保
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Abstract

Osteoproliferation, the pharmaceutical composition of lumbocrural pain are treated the invention discloses a kind of, raw material includes the component of following weight proportion: frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, and 4-8 parts respectively；Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.5-1 parts respectively；Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.25-8.25 parts respectively；2-6 parts of borneol；6-10 parts of Semen Strychni (processed).Drug matching of the present invention is scientific and reasonable, medicinal material mutually cooperates with, plays drug effect altogether respectively, have the effects that activating microcirculation and removing stasis medicinal, expelling wind and clearing away cold, promoting qi circulation and relieving pain, tonify the liver and kidney, dissipate blood stasis and smoothing collaterals, swelling and pain relieving, warming channel and expelling cold, broken resistance eliminating impediment, for cervical spondylosis, scapulohumeral periarthritis, osteoproliferation, pain can play the role of good curative effect caused by lumbar vertebrae shoulder disk is prominent, spur pricks pain, lumbar muscle strain, extremities joint is sick.

Description

It is a kind of to treat osteoproliferation, pharmaceutical composition of lumbocrural pain and preparation method thereof
Technical field
Osteoproliferation, pharmaceutical composition of lumbocrural pain and preparation method thereof are treated the present invention relates to a kind of.
Background technique
It is well known that various osteopathy are summarized as numbness disease scope, there are many pathogenesis, such as chill wet evil, old regression, labor Damage, sprain, excess load weight weigh wounded, for a long time by it is wet, wind-engaging, heresy of catching cold vertebra can be caused respectively to organize regression aging, break Damage, disk protrusion, osteoproliferation and aseptic inflammation cause each wounded tissue hyperemia, oedema, swelling, adhesion, and cervical spondylosis can press Urgent nerve cause shoulder pain, hand fiber crops, shoulder acid is swollen, the powerless atrophy of muscle, general weakness, lumbar vertebrae pressuring nerve if oppressing vertebral artery Root, dural sac cause that sciatica, waist-leg numb pain, limbs send out cool or even lower limb paralysis.Waist-leg and arthralgia are one The common clinical symptoms of kind, patient's lumbocrural pain, it is difficult to which prostrate or walking, joint crooked radian reduce, and bring pole for life Big inconvenient, other than causing damage by outside, body interior disequilibrium also results in the symptom.
Cervical spondylosis, also known as cervical spine syndrome are osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, cervical vertebra The general name of Spondylosis disease is a kind of illness that basis is changed into degeneration pathology.Mainly due to long-term strain, hyperostosis Raw or Disc herniation, ligament thicken, and cause cervical vertebra spinal cord, nerve root or vertebral artery to be pressurized, a series of dysfunctions occur Clinical syndrome.It shows as vertebra section unstability, loosen；Nucleus pulposus or abjection；Spur is formed, and ligament plumpness and secondary canalis spinalis are narrow It is narrow etc., the tissue such as the nerve root closed on, spinal cord, vertebral artery and neck sympathetic nerve is stimulated or oppressed, a series of symptoms is caused And sign.
Lumbar vertebra disease is exactly that lesion occurs for the sclerotin of vertebra, interverbebral disc, ligament, muscle, so oppress, traction stimulation spinal cord, Spinal nerve, blood vessel, vegetative nerve are to complicated and diversified symptom occur.Common disease is cervical spondylosis, lumbar vertebra disease.Cardinal symptom: Cannot upright, headache, dizziness, eye-blurred, decrease of memory, neck and shoulder pain, loss of appetite, gastric disorder causing nausea, vomiting, weakness of the lower extremities, Serious person may cause paralysis.
Hyperostosis is mainly in above middle age, it is considered that due to having a delicate constitution after the middle age and retrogression；For a long time It stands or walks and be held in certain posture for a long time, due to the drawing of muscle or avulsion, bleeding, organization of hematoma forms thorn-like Or the osteoproliferation of lip sample；Spur to soft tissue generate it is mechanical stimulation and wound after soft tissue injury, bleeding, swelling and It causes.
Treatment method has physical therapy, externally applied drug, traditional Chinese medicine for oral administration, non-antibody class anti-inflammatory analgesic medicine, operative treatment, object at present Physical therapy method can only realize local treatment, and cannot be adjusted on the whole, and effect is not ideal enough；Medicine toxicity for oral administration is big, unsuitable Long term usage；Operative treatment, wound is big, and risk is high, and patient is not easily accepted by.
Summary of the invention
The present invention is in order to overcome at least one of the drawbacks of the prior art described above (deficiency).
In order to solve the above technical problems, primary and foremost purpose of the invention is to provide and a kind of treats osteoproliferation, lumbocrural pain Pharmaceutical composition, raw material include the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 4-8 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.5-1 parts respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.25-8.25 parts respectively；
2-6 parts of borneol；
6-10 parts of Semen Strychni (processed).
Preferably, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 5-7 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.6-0.9 parts respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 5.25-7.25 parts respectively；
3-5 parts of borneol；
7-9 parts of Semen Strychni (processed).
Preferably, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 6 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.75 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 6.25 parts respectively；
4 parts of borneol；
8 parts of Semen Strychni (processed).
Preferably, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 4.5 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.55 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.75 parts respectively；
2.5 parts of borneol；
6.5 parts of Semen Strychni (processed).
Preferably, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 7.5 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.95 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 7.75 parts respectively；
5.5 parts of borneol；
9.5 parts of Semen Strychni (processed).
It is yet another object of the invention to provide one it is a kind of treat osteoproliferation, lumbocrural pain drug preparation method, packet Include following steps:
S1. the component of weight proportion described above is mixed and beats powder；
S2. it moistens and reconciles.
Preferably, wet reconcile is reconciled using wine, sesame oil, vinegar.
Preferably, it moistens after reconciling, is externally applied to the position of pain.
Preferably, primary to apply 12 hours, 7 days as one therapeutic course.
Frankincense: taking the olibanum for picking net, sets in pot and slightly sees melting point with being fried with slow fire surface, is slightly in yellow, taking-up cools； Or fry when being dissolved to surface, rice vinegar is sprayed, continues to fry saturating to outer layer bright light, taking-up cools.Energy regulating qi and activating blood, analgesic therapy chase after poison. Control qi and blood stagnation, trusted subordinate's pain, ulcerative carbuncle pyogenic infections, traumatic injury, dysmenorrhea, postpartum blood stasis stabbing pain.
Myrrh: the agglomerate or fritter of irregular shape, long 1-2cm.Surface is dark brown to dark brown, and coarse, matter is hard, is crushed Face sepia；Gas is fragrant special, bitter.Control traumatic injury, metal-inflicted wound, muscles and bones, all pains of trusted subordinate, abdominal mass, menostasis, ulcer sore pain, anal fistula, Mesh barrier.Bitter, it is pungent, it puts down.
Dragon's blood: nature and flavor: sweet in flavor；It is salty；It is mild-natured；Mild toxicity.Channel tropism: the heart channel of Hang-Shaoyin；Liver Channel.Function: scattered stasis pain；Hemostasis；Myogenic is held back Sore.The major functions: traumatic injury；Internal injury stasis caused pain；Dysmenorrhea；Postpartum stasis abdominal pain；Traumatic hemorrhage is more than；Scrofula；Ulcer on the shank burst long do not conform to and Hemorrhoid.
Psoralea corylifolia: pharmacological property: bitter, pungent, warm.Return kidney, the spleen channel.Effect tonifying kidney and strengthening yang, retention of essence and urine, kidney deficiency and lumbago, urine frequency Number, infantile enuresis, kidney leakage, warming spleen and stopping diarrha, gas of receiving is relievingd asthma.For treating impotence due to deficiency of the kidney, soreness and weakness of waist and knees crymodynia, emission due to the kidney deficiency is lost Urine, frequent micturition etc..For treating Diarrhoea caused by the insufficiency of both the spleen and the kindey.The cold of insufficiency type for treating the failure of the kidney in receiving air is breathed with cough.
Aconiti preparata,radix: property heat, acrid flavour, hardship are very toxic；Return heart, liver,kidney,spleen warp.Function with dispelling wind and eliminating dampness, antalgic Effect is used for treating arthralgia due to cold and dampness, the diseases such as arthralgia.
Wild aconite root: acrid flavour, hardship, property heat.With dispelling wind and eliminating dampness, the effect of antalgic.It is used for treating arthralgia due to cold and dampness, arthritis Bitterly, the cool pain of trusted subordinate, cold hernia analgesic.
Safflower: blood circulation, removing blood stasis and acesodyne, facilitate controlling through closing, dysmenorrhea, lochia, chest impediment and cardialgia, stasis of blood, Pricking pain in the chest, traumatic injury, sore swell and ache curative curative effect.There is the effect of activating microcirculation and removing stasis medicinal, dissipate wet effect going to swell, pregnant woman is avoided to use, otherwise can It causes to miscarry.
Lopseed: nature and flavor sweet, acrid, warm.Enter lung, liver two passes through.1. dispelling wind and eliminating dampness of effect, the product pungent-warm, pungent energy, which be manageed it, to be dissipated, Temperature overcomes the coldness wet.Enter Liver Channel, thus can dispelling wind and eliminating dampness, " control all rheumatalgia pain contractures of muscles and bones as Compendium of Material Medica is said: lopseed.If " Lead to limbs pain because wind-cold damp pathogen invades limbs channels and collaterals, numb, joint stuffiness.The product can be selected, expelling wind and clearing away cold victory is wet, disease Heresy is gone, then all disease self-healing.2. relaxing tendons and activating collaterals, the pungent scattered temperature of the product is logical, enters Liver Channel, and liver governing tendons therefore the product have relaxing tendons and activating collaterals it Effect.For the heresy of affection of exogenous wind-cold, a surname is lost through gas symptoms include limbs tendon and vessel is shunk and taken out suddenly, cannot relax and turn freely.It can be selected deep Grass, expelling wind and clearing away cold, relaxing tendons and activating collaterals control it.If " choosing of Shan Gan Ningqing Chinese herbal medicine " selects the product, muscles and bones muscular constricture is controlled.3. promoting blood circulation stops Bitterly, the pungent scattered temperature of the product is logical, enters Liver Channel blood system, therefore can promoting blood circulation and stopping pain.Above and below, trusted subordinate's waist and knee, inside and outside various pain, The product can be selected and control it, its pungent-warm is taken to be apt to walk, the function of promoting blood circulation and benefiting qi, vim and vigour no pain by smooth breath.4. solution poisons rash, the secret red medicine writing paper of spirit " It says: " treating heat toxin." " Yang Cheng Empirical formula " selects the product, control pyogenic infections from the beginning of." choosing of Shan Gan Ningqing Chinese herbal medicine " controls scrotum then with the product Eczema, sore swollen toxin.Therefore lopseed treatment ringworm sore pyogenic infections, eczema of scrotum, general more (drugs)s to be decocted and used as a lotion can be thought.Also because of this medicine washout Priming penetrates channels and collaterals, blood vessels, and the characteristics of wind-dispelling, promoting blood circulation, analgesic.
Long-nosed pit viper: also known as long-noded pit viper.Its is warm-natured, sweet in flavor, salty, toxic.Return liver warp.With expelling wind and clearing away cold, relaxing tendons and activating collaterals, analgesia Antipruritic effect.For rheumatic arthritis, pruitus, child convulsion, arthralgia, leprosy, tetanus, scabies, red bayberry Sore, scrofula malignant sore, hemiplegia, apoplexy facial paralysis, spasm of twitching, rheumatoid arthritis stubborn, extremity numbness, the diseases such as coronary heart disease have treatment Effect.In addition, long-nosed pit viper also expands blood vessel, improve microcirculation, reduces blood lipid, anticoagulant, the effect of anti-bolt.
Chinese azalea fruit: Chinese azalea fruit is the fruit of ericad Chinese azalea, is dispelled pathogenic wind and remove dampness, and removing blood stasis and acesodyne, Dingchuan is only formed sediment, Main wind-cold-dampness arthralgia, joint-running swelling and pain, traumatic injury are breathed with cough, dysentery, swollen ulcer drug.
Corydalis tuber: warm-natured, acrid flavour, hardship；Return liver, the spleen channel.Have the effect of promoting blood circulation, sharp gas, analgesic, for chest side of body, epigastric pain, The diseases such as amenorrhea and algomenorrhea, postpartum stasis, tumbling and swelling.
House lizard: it is salty, it trembles with fear, it is slightly poisonous.Curing mainly paralysis due to windstroke, brothers do not lift or severe and wadering arthralgia pain and wind frightened epilepsy, infantile emaciation, Blood accumulates scrofula, treats scorpion and stings (Shi Zhen).
Centipede: it is acrid in flavour and warm in nature, it is toxic.Shi Zhen is said: fear slug, spider, chicken droppings, mulberry skin, white salt." curing mainly " ghost Zhu disease due to noxious agents produced by various parasites, eats all Snake, worm, ichthyotoxin kill ghost smart a kind of malaria always, go three worms (Shennong's Herbal).The accumulation of trusted subordinate's fever and chills is treated, extravesated blood (" Bie Lu ") is gone in induced abortion. Control disease addiction (" solar corona ").Pediatric epilepsy scared tetany, umbilical tetanus lockjaw, erysipelas favus of the scalp scrofula snakebite (Shi Zhen).
Eupolyphoge sinensis: it is salty, it trembles with fear；It is slightly poisonous.Return liver warp.Function with the major functions: broken stasis of blood blood, continuous muscles and bones.For injured bone, hemostasis warp It closes, abdominal mass lump in the abdomen.Chinese medicine function: (1) hemostasis under, eliminating mass lump in the abdomen treat injured: being used for blood stasis, traumatic injury and abdominal mass lump. (2) removing blood stasis and acesodyne: for the swelling and pain of liver and spleen caused by blood stasis and lumbar muscle strain, strain.
Pubescent angelica root: it is pungent, it puts down.Lung channel.Antipyretic, heat-clearing and detoxifying drug.[effect]: antibacterial anti-inflammatory, dispelling wind and eliminating dampness, promoting blood circulation Analgesic.Control pneumonia, acute appendicitis, acute gastroenteritis, bacillary dysentery, rheumatalgia pain, traumatic injury, fracture.
The root of Chinese clematis: Xin Xian, temperature are toxic.Enter bladder meridian.Dispelling wind and eliminating dampness is removed obstruction in channels to relieve pain, dissolving phlegm water, dissipating the hypochondriac lump.Cure mainly gout Stupid numbness, rheumatic arthralgia, extremity numbness, waist and knee crymodynia, muscle arteries and veins contraction, joint stuffiness, tinea pedis, malaria, a lump in the abdomen causing distension and pain, tetanus, Tonsillitis, all bone sticking swallow.
Radix dipsaci: nourishing liver and kidney, continuous muscles and bones adjust blood vessels.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia and metrostaxis, leukorrhagia, spermatorrhea falls Beat damage, metal-inflicted wound, anal fistula, ulcer sore swells.
The rhizome of davallia: The strong bone of kidney tonifying, continues and hinders pain relieving.For lumbago due to the kidney deficiency, Hiccough and deaf, tooth mobility, falling winks frustrates, muscles and bones Injured；Control outward alopecia areata, leucoderma.
False wintergreen: also known as pyrola, wintergreen, because be deer rank come cure the disease medicinal herbs due to gain the name.It has dispelling wind and eliminating dampness, strong Strengthen the bone, stop blooding, kidney tonifying, qi-restoratives, promoting blood circulation, adjust menstruation, hemostasis the effect of, can be used for treating lumbago due to the kidney deficiency, rheumatoid arthrosis numbness pain, Waist and knee muscles and bones impotence is powerless, acute and chronic is coughed, haematemesis, nosebleed, anovulatory dysfunctional uterine caused by disease of digestive system The illnesss such as bleeding, traumatic hemorrhage, abnormal leucorrhea.Modern pharmacology research thinks, false wintergreen also has antibacterial, strengthen immunity Effect.
Rhizoma cibotii: it is rhizoma cibotii bitter, sweet, it is warm-natured；Return liver and kidney channel；Matter heavily fortified point row dissipates, and drops and can rise；With strong waist and knee, wind-damp dispelling, Reinforce the kidney gas the effect of；It is strong to cure mainly lumbago due to the kidney deficiency ridge, sufficient knee is weak and feeble, rheumatic arthralgia, the enuresis, frequent micturition, spermatorrhea, leukorrhea.
Rhizoma Chuanxiong: taste is acrid in flavour and warm in nature.Promote breath and open depression, it is wet to dispel wind-dryness, promoting blood circulation and stopping pain.It is dizzy to control air-cooled headache rotation, hypochondriac pain abdomen pain is trembled with fear Numbness muscle contraction, menostasis, difficult labour, postpartum stasis block pain, ulcer sores.For irregular menstruation, amenorrhea and algomenorrhea, lump in the abdomen abdominal pain, pricking pain in the chest, Tumbling and swelling, headache, rheumatic arthralgia.
Borneol: it is arduous, it is cool.Lead to all keys, dissipates stagnated fire, remove screen improving eyesight, swelling and pain relieving.Control apoplexy lockjaw, pyreticosis coma, frightened epilepsy Phlegm confusing heart, deafness with qi stagnation, sore throat, aphtha, tympanitis, carbuncle swells, hemorrhoid, mesh also screen film, enterobiasis.
Semen Strychni (processed): promoting blood circulation and removing obstruction in channels；Vomiting nut has the effect of relaxing tendons and activating collaterals, cold dispelling dredging collateral.For breast lump, ulcer is swollen Pain has good curative effect.Antiphlogistic antibacterial: vomiting nut also has anti-inflammatory effect, has suitable for nonspecific inflammation ulcer sore pain certain Curative effect.Analgesic: vomiting nut is that Chinese medicine relieves pain most effective one of drug, and especially newborn pain treating rheumatic ostealgia, muscular injury pain has Special efficacy.Expelling the stasis for the new: vomiting nut is to polio, and numb in every limb, anticancer etc. also has certain effect.
Compared with prior art, the beneficial effect of technical solution of the present invention is:
1) drug matching of the present invention is scientific and reasonable, and each medicinal material mutually cooperates with, plays drug effect altogether, and there is activating microcirculation and removing stasis medicinal, wind-dispelling to dissipate Tremble with fear, promoting qi circulation and relieving pain, tonify the liver and kidney, dissipate blood stasis and smoothing collaterals, swelling and pain relieving, warming channel and expelling cold, broken resistance eliminating impediment the effects of, for cervical spondylosis, shoulder Zhou Yan, osteoproliferation, lumbar vertebrae shoulder disk protrusion, spur are pricked pain caused by pain, lumbar muscle strain, extremities joint disease and can be played very well Curative effect effect.
2) present invention is using traditional Chinese medicine and pharmacy theory as foundation, unsmooth because being that numbness hinders channels and collaterals, QI-blood circulation using pain as primary symptom And lead to neck, limbs, waist-leg, arthralgia；Therefore be monarch with many flavour of a drug promoting blood circulation and removing obstruction in channels, swelling and pain relieving, with many scattered stasis of bloods, The flavour of a drug of detumescence ding-tong are minister, are assistant with many detoxicating and resolving a masses, dehumidifying, easing joint movement flavour of a drug；All medicine compatibilities, conjunction and with it, Allow medicament to promoting menstruation and walk that network, opening block and activating stagnancy, the painization that disappears is become silted up, go directly its institute, thus achieve the purpose that qi and blood circulation and disease from clear； The function of warm nourishing liver and kidney, strengthening the spleen and replenishing qi, cold dispelling dispelling wind and eliminating dampness, eliminating blood stasis and smoothing collaterals analgesic therapy is played altogether in full side.
3) effective component of the invention can pass through skin and go directly affected part, generate activating microcirculation and removing stasis medicinal, promoting menstruation walk network, have one's ideas straightened out it is deep, The effect of expelling wind and clearing away cold, and regulation machine balance can be acted on by the channel tropism of drug, promote local blood circulation, it strengthens the body resistance to consolidate the constitution, from And achieve the purpose that eliminate ailing.The present invention can improve rapidly local blood circulation, proceed blood cycle, recover stagnation resolvation, therefore reduce swelling Analgesic effect is very good.
4) present invention has strengthening the muscles and bones, relaxing tendons and activating collaterals, promoting blood circulation and stopping pain, dispersing swelling and dissipating binds and other effects.To protrusion of lumber intervertebral disc, Osteoproliferation, sclerotin retrogression pathological changes etc. are significant in efficacy, have unique curative effect to cervical spondylosis.
5) therapy of the present invention is quick, expense is low.
Specific embodiment
Using obtained by purchase marketed drugs in the present invention.The present invention is described in detail below.
A kind of to treat osteoproliferation, the pharmaceutical composition of lumbocrural pain, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 4-8 parts of (i.e. every samples of difference Medicine is 4-8 parts)；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.5-1 parts respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.25-8.25 parts respectively；
2-6 parts of borneol；
6-10 parts of Semen Strychni (processed).
As the improvement of specific embodiment, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 5-7 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.6-0.9 parts respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 5.25-7.25 parts respectively；
3-5 parts of borneol；
7-9 parts of Semen Strychni (processed).
As the improvement of specific embodiment, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 6 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.75 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 6.25 parts respectively；
4 parts of borneol；
8 parts of Semen Strychni (processed).
As the improvement of specific embodiment, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 4.5 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.55 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.75 parts respectively；
2.5 parts of borneol；
6.5 parts of Semen Strychni (processed).
As the improvement of specific embodiment, raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 7.5 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.95 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 7.75 parts respectively；
5.5 parts of borneol；
9.5 parts of Semen Strychni (processed).
It is a kind of treat osteoproliferation, lumbocrural pain drug preparation method, comprising the following steps:
S1. by frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, long-nosed pit viper, Chinese azalea fruit, House lizard, Eupolyphoge sinensis, pubescent angelica root, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong, borneol, Semen Strychni (processed) at centipede, presses Powder is beaten in the component mixing of weight proportion described above；
S2. it moistens and reconciles.
As the improvement of specific embodiment, wet reconciliation is reconciled using wine, sesame oil, vinegar.Medicine after powder is sprayed because mixing Powder deal is larger, is generally half jin or more using wine, sesame oil, vinegar every time, stirring becomes sposh state.
As the improvement of specific embodiment, moistens after reconciling, be externally applied to the position of pain.
It is primary/to apply 12 hours daily, 7 days as one therapeutic course as the improvement of specific embodiment.
Specific embodiment 1
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 4 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.5 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.25 grams respectively；
2 grams of borneol；
6 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Specific embodiment 2
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 8 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 1 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 8.25 grams respectively；
6 grams of borneol；
10 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Specific embodiment 3
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 5 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.6 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 5.25 grams respectively；
3 grams of borneol；
7 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Specific embodiment 4
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 7 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.9 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 7.25 grams respectively；
5 grams of borneol；
9 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Specific embodiment 5
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 6 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.75 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 6.25 grams respectively；
4 grams of borneol；
8 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Specific embodiment 6
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 4.5 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.55 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.75 grams respectively；
2.5 grams of borneol；
6.5 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Specific embodiment 7
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 7.5 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.95 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 7.75 grams respectively；
5.5 grams of borneol；
9.5 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Specific embodiment 8
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 5.5 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.7 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 6 grams respectively；
3.5 grams of borneol；
7.5 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Specific embodiment 9
It weighs by weight:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 6.5 grams respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.8 gram respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 6.75 grams respectively；
4.5 grams of borneol；
8.5 grams of Semen Strychni (processed).
After powder is beaten in mixing, reconciliation external application is carried out with wine, sesame oil, vinegar using preceding.Once/apply daily 12 hours, it is treated for one within 7 days Journey.
Exemplary embodiments
The medicinal powder of preparation of the embodiment of the present invention is highly-safe and good effect has been controlled over 20 years altogether since the applicant takes up a job as a doctor The osteoproliferation for the treatment of, lumbocrural pain patient 3951, wherein 90% or more patient various pain after one or two moon of medication obtain To mitigation or disappear；Protrusion of lumber intervertebral disc is treated, the patient of osteoproliferation there are 1302 column, and cervical vertebrae hyperosteogeny patient has 1827 People, improvement rate is up to 90% or more.Wherein, good therapeutic effect is shown for patient with severe symptoms (patient with severe symptoms is generally equipped with Medicine for oral administration, medicine for oral administration mainly activate blood circulation and disperse blood clots, and relieve pain, and drug adds and subtracts prescription with the physical condition of patient！).Specific case is such as Under:
1, king xx, male, 62 years old.CT shows that L3/4, L4/5, L5/S1 interverbebral disc go out；And degenerative lumbar.It is applied with this medicine and matches Heal up the pain relief in January that takes traditional Chinese medicine.
2, horse xx, female, 54 years old.CT shows L3/4, L4/5, L5/6 bulge or bulging；Cervical spinal canal narrows, cervical spondylosis.Outside It applies this medicine and is cured substantially after cooperation oral traditional Chinese medicine 2 months.
3, old xx is paralyzed in bed for 68 years old, can get up after being applied with and having eaten two courses for the treatment of.
4, Lee xx, 42 years old.Pain in the loins 5 years.Body is looked into: 3-5 lumbar vertebrae has obvious tenderness, and also there is tenderness in kidney area.CT:1. between lumbar vertebrae Disk is prominent.2. lumbar vertebrae hyperosteogeny.Diagnosis: 1 protrusion of lumber intervertebral disc.2. lumbar vertebrae hyperosteogeny.3. lumbar muscle strain.After one course for the treatment of Obviously take effect, pain relief.Two courses for the treatment of are cured.
5, Zhu xx, 71 years old.More than a year, limitation of activity, double upper limbs praise difficulty for patients with cervical, shoulder pain, and the proximal segment time goes out Existing dizziness, blood pressure 142/92.It has been applied with course for the treatment of healing.
6, Liao xx, male, 45 years old, shoulder aches 1 year, right upper extremity limitation of activity praised difficulty.Diagnose scapulohumeral periarthritis.In clothes Medicine, physical therapy, acupuncture and moxibustion therapy are also increasingly severe.Carry out my clinic treatment, a patch takes effect, and it is all right to be applied with a course for the treatment of.
Part that the present invention does not relate to is the same as those in the prior art or can be realized by using the prior art.Obviously, of the invention The above embodiment is merely an example for clearly illustrating the present invention, and is not the limit to embodiments of the present invention It is fixed.For those of ordinary skill in the art, it can also make on the basis of the above description other various forms of Variation changes.There is no necessity and possibility to exhaust all the enbodiments.All within the spirits and principles of the present invention Made any modifications, equivalent replacements, and improvements etc., should all be included in the scope of protection of the claims of the present invention.

Claims (9)

1. a kind of treat osteoproliferation, the pharmaceutical composition of lumbocrural pain, which is characterized in that its raw material includes following weight proportion Component:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 4-8 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.5-1 parts respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.25-8.25 parts respectively；
2-6 parts of borneol；
6-10 parts of Semen Strychni (processed).
2. treatment osteoproliferation, the pharmaceutical composition of lumbocrural pain according to claim 1, which is characterized in that its raw material Component including following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 5-7 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.6-0.9 parts respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 5.25-7.25 parts respectively；
3-5 parts of borneol；
7-9 parts of Semen Strychni (processed).
3. treatment osteoproliferation, the pharmaceutical composition of lumbocrural pain according to claim 1, which is characterized in that its raw material Component including following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 6 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.75 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 6.25 parts respectively；
4 parts of borneol；
8 parts of Semen Strychni (processed).
4. treatment osteoproliferation, the pharmaceutical composition of lumbocrural pain according to claim 1, which is characterized in that its raw material Component including following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 4.5 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.55 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 4.75 parts respectively；
2.5 parts of borneol；
6.5 parts of Semen Strychni (processed).
5. pharmaceutical composition according to claim 1, which is characterized in that its raw material includes the component of following weight proportion:
Frankincense, myrrh, dragon's blood, psoralea corylifolia, aconiti preparata,radix, wild aconite root, safflower, lopseed, 7.5 parts respectively；
Long-nosed pit viper, Chinese azalea fruit, house lizard, centipede, 0.95 part respectively；
Eupolyphoge sinensis, the root of Chinese clematis, fries radix dipsaci, the rhizome of davallia, false wintergreen, rhizoma cibotii, Rhizoma Chuanxiong at pubescent angelica root, and 7.75 parts respectively；
5.5 parts of borneol；
9.5 parts of Semen Strychni (processed).
6. it is a kind of treat osteoproliferation, lumbocrural pain drug preparation method, comprising the following steps:
S1. the component of weight proportion described in claim 1-5 is mixed and beats powder；
S2. it moistens and reconciles.
7. the preparation method of the drug for the treatment of osteoproliferation according to claim 5, lumbocrural pain, it is characterised in that step S2 is wet to be reconciled, and is reconciled using wine, sesame oil, vinegar.
8. the preparation method of the drug for the treatment of osteoproliferation according to claim 5, lumbocrural pain, it is characterised in that step After the wet reconciliation of S2, it is externally applied to the position of pain.
9. the preparation method of the drug for the treatment of osteoproliferation according to claim 8, lumbocrural pain, it is characterised in that step It is applied with after the wet reconciliation of S2, primary to apply 12 hours, 7 days as one therapeutic course.
CN201910678264.5A 2019-07-25 2019-07-25 It is a kind of to treat osteoproliferation, pharmaceutical composition of lumbocrural pain and preparation method thereof Pending CN110227117A (en)

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CN114699363A (en) * 2022-06-08 2022-07-05 江西中医药大学附属医院 Traditional Chinese medicine wax mud for osteoarthritis and preparation method thereof

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Publication number Priority date Publication date Assignee Title
CN1285196A (en) * 2000-08-28 2001-02-28 赵芳可 Shubi plaster for treating arthralgia due to wind-cold-dampness
CN109010561A (en) * 2018-10-10 2018-12-18 孙斌 A kind of plaster and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1285196A (en) * 2000-08-28 2001-02-28 赵芳可 Shubi plaster for treating arthralgia due to wind-cold-dampness
CN109010561A (en) * 2018-10-10 2018-12-18 孙斌 A kind of plaster and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114272313A (en) * 2020-09-26 2022-04-05 贵港市平南县桂福鑫生物科技有限责任公司 External-use anti-inflammation sterilizing detumescence analgesic liquid
CN114699363A (en) * 2022-06-08 2022-07-05 江西中医药大学附属医院 Traditional Chinese medicine wax mud for osteoarthritis and preparation method thereof

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