CN105770070A - Method for preparing orthopedic and traumatology astringency and hemostasis medicinal liquor - Google Patents

Method for preparing orthopedic and traumatology astringency and hemostasis medicinal liquor Download PDF

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CN105770070A
CN105770070A CN201610142154.3A CN201610142154A CN105770070A CN 105770070 A CN105770070 A CN 105770070A CN 201610142154 A CN201610142154 A CN 201610142154A CN 105770070 A CN105770070 A CN 105770070A
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不公告发明人
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    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention discloses a method for preparing orthopedic and traumatology astringency and hemostasis medicinal liquor. The orthopedic and traumatology astringency and hemostasis medicinal liquor is mainly prepared from the following raw material medicines in parts by weight: 8-16 parts of peach kernels, 3-6 parts of tinospora sinensis, 4-8 parts of roots of Korean raspberry, 5-10 parts of hematoxylon, 6-9 parts of grewia lantsangensis, 2-5 parts of gaultheriayunnanensis and a proper amount of liquor. The components completely meet the principles of traditional Chinese medicines and have effects of stopping bleeding and relieving pain, activating blood and removing swelling as well as tonifying kidney and strengthening bone, and the prepared medicinal liquor can be both drunk and rubbed at affected parts and is low in long-term drinking expense as the medicinal materials are cheap and easy to obtain.

Description

The preparation method of orthopedics and traumatology astringing to arrest bleeding medicinal liquor
Divisional application, original applying number 2014107525053, applying date 2014.12.11, title orthopedics and traumatology astringent hemostatic Wine and preparation method.
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of orthopedics and traumatology astringing to arrest bleeding medicinal liquor and preparation method thereof.
Background technology
In life, people can be because a variety of causes be caused interior wound by the impact of external force.The lighter injures surface skin, weight Person gos deep into muscles and bones, and for made hemorrhage of wound, it is very important for make hemostasis timely processing, and otherwise can cause the life of the wounded Threaten.Some wounds going deep into muscles and bones not only result in haemophilia, also can affect the motor function of the wounded, modal in bone fracture Illness surely belongs to fracture, and fracture is the bone parts caused by wound or disease or the person that completely do not fractures, how because of external force, myotility or osteopathy Caused.Main clinical manifestation is that fractures has localized pain and a tenderness, local swelling and ecchymosis occur, limb function position Or completely lose, affected part can have hemostasis, swell and ache, misplace, deformity, bone sound, axle center percussion pain, abnormal movement and dysfunction etc. are planted Plant performance.In addition, traumatic injury, extruding torsion, knife wound all can cause internal surface of bone wound and the breakage of flesh table etc..Bone fracture Treatment needs difference according to circumstances to carry out different treating, the traditional Chinese medical science treatment to bone fracture, and primary treatments has bonesetting, consolidates Fixed, medicines etc., ancillary drug is many based on anti-inflammatory, detumescence with invigorate blood circulation, and for the treatment of wound hemostasis, is usually neglected by people Slightly.Publication number CN 103989744 A(application number 201410256869.2) Chinese patent literature disclose a kind of for treating Medicinal liquor of fracture and its preparation method and application, consists of obovateleaf actinodaphne bark 20-30 part, beans leaf seven 15-25 part, purple swallow grass 8-12 Part, fragrant stone rattan 8-12 part, rhizome of davallia 10-14 part, root of three-nerved spicebush 18-22 part.Publication number CN 103417761 A(application number 201310365293.9) Chinese patent literature discloses one and treats fracture, osteoporotic medicinal liquor, and this medicinal liquor is by bajiao banana Root, creeping oxalis, teasel root, pseudo-ginseng, Psoralea corylifolia, barrenwort, bark of eucommia composition.Publication number CN 103463572 A(application number Chinese patent literature 201310424145.X) disclose a kind for the treatment of sprain, the medicinal liquor fractured and preparation method, by the banksia rose 15-30g, Fructus Aurantii 10-30g, myrrh 20-35g, curcuma zedoary 20-35g, plantain seed 20-40g, rascal 15-35g, rhizoma dioscoreae nipponicae 10-40g, Dried rhizome of rehmannia 10-40g, bark of eucommia 20-40g, safflower 10-40g, cape jasmine 15-40g, frankincense 20-40g, teasel root 15-40g, akebi 15-35g, 65 degree of white wine 5 15kg make.
China's medicinal liquor having many set a broken bones among the people, but the medicinal liquor that conventional method makes, result for the treatment of is unsatisfactory, for More preferable help patient with bone fracture alleviates the pain of injury, and still needing to keep punching, it is a kind of effective to develop, clinical efficacy good controlling Treat the astringing to arrest bleeding medicinal liquor of bone fracture.
Summary of the invention
For the deficiencies in the prior art, it is an object of the invention to provide orthopedics and traumatology reliable, clothes the most for a long time the convergence of a kind of curative effect Hemostasis medicinal liquor and preparation method.
The technical scheme is that
Orthopedics and traumatology astringing to arrest bleeding medicinal liquor, is mainly prepared from by following bulk drugs, is weight portion: peach kernel 8-16, wide muscle rattan 3- 6, korean raspberry root 4-8, bush 5-10, prairie fire rope 6-9, deep fragrant 2-5, white wine is appropriate.
Preferably in scheme, peach kernel 10-14, wide muscle rattan 4-5, korean raspberry root 5-7, bush 6-9, prairie fire rope 7-8, deep fragrant 3- 4, white wine is appropriate.
More preferably, peach kernel 12, wide muscle rattan 4.5, korean raspberry root 6, bush 7.5, prairie fire rope 7.5, deep fragrant 3.5, white wine In right amount.
The preparation method of described orthopedics and traumatology astringing to arrest bleeding medicinal liquor is:
(1) take korean raspberry root decontamination, be cut into small pieces, explode to surface brown color with edible oil, take out, drain oil, cool;(2) by peach Benevolence decontamination, is placed in pot, adds salt solution and stirs to parching, takes out;
(3) taking prairie fire rope, wide muscle rattan and deep fragrant decontamination, infiltration, chopping, be subsequently placed in frying pan, little fire is fried to savory Time, take out, dry in the air cool;
(4) by bush decontamination, clean, be placed in baking oven together with step (1) (2) (3) made medicinal material, dry, pulverize and sieve, Being subsequently placed in pot, add 30 degree of white wine, big fire is boiled, and finally closes fire and is cooled to normal temperature, pour in vial, seal, soaks 10- After 20 days, filter, remove the dregs of a decoction, obtain astringing to arrest bleeding medicinal liquor.
The preparation method of described orthopedics and traumatology astringing to arrest bleeding medicinal liquor, step (1) edible oil is tung oil.
The preparation method of described orthopedics and traumatology astringing to arrest bleeding medicinal liquor, amount is medicinal material weight 0.3 times of step (2) salt solution, Wherein salt is 1:30 with the mass ratio of water.
The preparation method of described orthopedics and traumatology astringing to arrest bleeding medicinal liquor, step (4) was pulverized 40-80 mesh sieve and (preferably, was pulverized Cross 50-70 mesh sieve;More preferably, 60 mesh sieves were pulverized).
The preparation method of described orthopedics and traumatology astringing to arrest bleeding medicinal liquor, amount is whole quality of medicinal material the 6 of step (4) white wine Times.
The preparation method of described orthopedics and traumatology astringing to arrest bleeding medicinal liquor, (preferably, big fire in 10-20 minute is boiled in step (4) big fire Boil 12-18 minute;More preferably, big fire boils 15 minutes).
The preparation method of described orthopedics and traumatology astringing to arrest bleeding medicinal liquor, step (4) is soaked 12-18 days and (preferably, is soaked 15 My god).
Used by the present invention, the pharmacology of main Chinese medicine material is as follows:
Peach kernel: base: for rosaceous plant peach or the dry mature seed of mountain peach.Nature and flavor: bitter, sweet, flat.Gui Jing: the thoughts of returning home, liver, Large intestine channel.Function cures mainly: promoting blood circulation, relaxes bowel.For through closing, dysmenorrhoea, lump in the abdomen lump in the abdomen, injury from falling down, the dry constipation of intestines.
Wide muscle rattan: base: for the stem of menispermaceae plant Tinospora sinensis.Nature and flavor: mildly bitter flavor;Cool in nature.Gui Jing: Liver Channel.Merit Can cure mainly: wind-expelling pain-stopping;Stimulate the circulation of the blood and cause the muscles and joints to relax.Main air pain of dampness syndrome;Lumbar muscle strain;Traumatic injury.
Korean raspberry root: base: for the root of rosaceous plant rubus coreanus.Nature and flavor: pained;Flat;Nontoxic.Gui Jing: liver;Kidney channel.Merit Can cure mainly: promoting blood circulation and hemostasis, dispel rheumatism.Main traumatic injury, fracture, irregular menstruation, spit blood, bleeding from five sense organs or subcutaneous tissue, arthralgia due to wind-dampness, oedema is little The most unfavorable, scrofula.
Prairie fire rope: base: for the root white skin of Tiliaceae plant comospore bilobed grewia.Nature and flavor: puckery;Micro-hardship;Cool.Function cures mainly: Hemostasis;Synthetism;Myogenic;Removing toxic substances.Main traumatism and bleeding;Weapons damage;Fracture;Sore furuncle is red and swollen.
Deep perfume (or spice): base: for the cauline leaf of ericad Yunnan Gaultheria.Nature and flavor: pungent;Warm in nature.Gui Jing: lung;Liver;Kidney Warp.Function cures mainly: dispel rheumatism;Eliminating cold to stop pain;Promoting blood circulation and removing obstruction in channels;Preventing phlegm from forming and stopping coughing.Main air pain of dampness syndrome;Stomach cold pain;Traumatic injury; Cough ant phlegm.
Bush: base: for the dry duramen of pulse family Caesalpinia bush.Nature and flavor: sweet, salty are flat.Gui Jing: the thoughts of returning home, liver, The spleen channel.Function cures mainly: row blood and dissolving stasis, swelling and pain relieving.For through closing dysmenorrhoea, postpartum stasis blocking, chest and abdomen shouting pain, wound swells and ache.
White wine: nature and flavor: sweet, bitter, pungent, temperature, poisonous.Gui Jing: enter the heart, liver, lung, stomach warp.Function cures mainly: promoting blood circulation, resisting cold Gas, row medicine gesture.Controlling chill numbness pain, muscle arteries and veins contraction is anxious, the obstruction of qi in the chest, trusted subordinate's crymodynia.
The orthopedics and traumatology astringing to arrest bleeding medicinal liquor scientific formula that the present invention provides, the preparation method of various formulations is simple, and gained produces Product taking convenience, it is easy to carry.In addition, the excellent results of the present invention is also manifested by:
1, this prescription complies fully with traditional Chinese medicine principle, has hemostasis and pain-relieving, activating blood circulation and reducing swelling, invigorating function of kidney and strengthening bone effect
2, made medicinal liquor is possible not only to drink, and also can embrocate affected part;
3, medicinal material is cheap and easy to get, and long-term taking expense is relatively low.
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not limited to this.
Embodiment 1 orthopedics and traumatology astringing to arrest bleeding medicinal liquor, is mainly prepared from by following bulk drugs: peach kernel 8g, wide muscle rattan 3g, Korean raspberry root 4g, bush 5g, prairie fire rope 6g, deep fragrant 2g, white wine is appropriate.
The preparation method of above-mentioned orthopedics and traumatology astringing to arrest bleeding medicinal liquor is:
(1) take korean raspberry root decontamination, be cut into small pieces, explode to surface brown color with tung oil, take out, drain oil, cool;(2) by peach Benevolence decontamination, is placed in pot, and the salt solution (salt is 1:30 with the mass ratio of water) adding medicinal material weight 0.3 times stirs to parching, Take out;
(3) taking prairie fire rope, wide muscle rattan and deep fragrant decontamination, infiltration, chopping, be subsequently placed in frying pan, little fire is fried to savory Time, take out, dry in the air cool;
(4) by bush decontamination, clean, be placed in baking oven together with step (1) (2) (3) made medicinal material, dry, pulverized 40 Mesh sieve, is subsequently placed in pot, adds 30 degree of white wine of whole quality of medicinal materials 6 times, and big fire is boiled 10 minutes, finally closes fire and is cooled to often Temperature, pours in vial, seals, and after soaking 10 days, filters, removes the dregs of a decoction, obtain astringing to arrest bleeding medicinal liquor.
Embodiment 2 orthopedics and traumatology astringing to arrest bleeding medicinal liquor, is mainly prepared from by following bulk drugs: peach kernel 16g, wide muscle rattan 6g, korean raspberry root 8g, bush 10g, prairie fire rope 9g, deep fragrant 5g, white wine is appropriate.
The preparation method of orthopedics and traumatology astringing to arrest bleeding medicinal liquor is:
(1) take korean raspberry root decontamination, be cut into small pieces, explode to surface brown color with tung oil, take out, drain oil, cool;(2) by peach Benevolence decontamination, is placed in pot, and the salt solution (salt is 1:30 with the mass ratio of water) adding medicinal material weight 0.3 times stirs to parching, Take out;
(3) taking prairie fire rope, wide muscle rattan and deep fragrant decontamination, infiltration, chopping, be subsequently placed in frying pan, little fire is fried to savory Time, take out, dry in the air cool;
(4) by bush decontamination, clean, be placed in baking oven together with step (1) (2) (3) made medicinal material, dry, pulverized 80 Mesh sieve, is subsequently placed in pot, adds 30 degree of white wine of whole quality of medicinal materials 6 times, and big fire is boiled 20 minutes, finally closes fire and is cooled to often Temperature, pours in vial, seals, and after soaking 20 days, filters, removes the dregs of a decoction, obtain astringing to arrest bleeding medicinal liquor.
Model case: xxx, man, 20 years old.After disputing with people, the other side takes cutter to make reprisals, and has little time to dodge, is chopped off the right side Forefinger and middle finger, go to see a doctor then, and synthetism is wrapped up.Introduce by friend and take the present embodiment gained orthopedics and traumatology astringent hemostatic Wine, every day 2 times, each 1-2 two, after taking 6 days, wound pain swelling is obviously improved, and takes to 30 days, and finger can be movable, X sheet Display fracture gap obscures, and after taking 40 days, finger function recovers completely.
Embodiment 3 orthopedics and traumatology astringing to arrest bleeding medicinal liquor, is mainly prepared from by following bulk drugs: peach kernel 10g, wide muscle rattan 4g, korean raspberry root 5g, bush 6g, prairie fire rope 7g, deep fragrant 3g, white wine is appropriate.
The preparation method of orthopedics and traumatology astringing to arrest bleeding medicinal liquor is:
(1) take korean raspberry root decontamination, be cut into small pieces, explode to surface brown color with tung oil, take out, drain oil, cool;(2) by peach Benevolence decontamination, is placed in pot, and the salt solution (salt is 1:30 with the mass ratio of water) adding medicinal material weight 0.3 times stirs to parching, Take out;
(3) taking prairie fire rope, wide muscle rattan and deep fragrant decontamination, infiltration, chopping, be subsequently placed in frying pan, little fire is fried to savory Time, take out, dry in the air cool;
(4) by bush decontamination, clean, be placed in baking oven together with step (1) (2) (3) made medicinal material, dry, pulverized 50 Mesh sieve, is subsequently placed in pot, adds 30 degree of white wine of whole quality of medicinal materials 6 times, and big fire is boiled 12 minutes, finally closes fire and is cooled to often Temperature, pours in vial, seals, and after soaking 12 days, filters, removes the dregs of a decoction, obtain astringing to arrest bleeding medicinal liquor.
Embodiment 4 orthopedics and traumatology astringing to arrest bleeding medicinal liquor, is mainly prepared from by following bulk drugs: peach kernel 14g, wide muscle rattan 5g, korean raspberry root 7g, bush 9g, prairie fire rope 8g, deep fragrant 4g, white wine is appropriate.
The preparation method of orthopedics and traumatology astringing to arrest bleeding medicinal liquor is:
(1) take korean raspberry root decontamination, be cut into small pieces, explode to surface brown color with tung oil, take out, drain oil, cool;(2) by peach Benevolence decontamination, is placed in pot, and the salt solution (salt is 1:30 with the mass ratio of water) adding medicinal material weight 0.3 times stirs to parching, Take out;
(3) taking prairie fire rope, wide muscle rattan and deep fragrant decontamination, infiltration, chopping, be subsequently placed in frying pan, little fire is fried to savory Time, take out, dry in the air cool;
(4) by bush decontamination, clean, be placed in baking oven together with step (1) (2) (3) made medicinal material, dry, pulverized 70 Mesh sieve, is subsequently placed in pot, adds 30 degree of white wine of whole quality of medicinal materials 6 times, and big fire is boiled 18 minutes, finally closes fire and is cooled to often Temperature, pours in vial, seals, and after soaking 18 days, filters, removes the dregs of a decoction, obtain astringing to arrest bleeding medicinal liquor.
Model case: xxx, man, 32 years old.Iron-smelting workers, during operation accidentally, hand is injured by machine, and skin fractured bone is revealed, blood flow Incessantly, being delivered to hospital by colleague, carry out disinfection, wrapping processes, and aftersensation medical expense is the most expensive, is out hospital after wrapping.Through old Township introduces and takes the present embodiment gained orthopedics and traumatology astringing to arrest bleeding medicinal liquor, twice daily, each 1-2 two, after taking 3 days, then without going out Blood, the surface of a wound starts to improve, after taking 10 days, it is seen that newborn meat, loses bone, takes to 30 days, wound healing, neoplastic skin Grow.
Embodiment 5 orthopedics and traumatology astringing to arrest bleeding medicinal liquor, is mainly prepared from by following bulk drugs: peach kernel 12g, wide muscle rattan 4.5g, korean raspberry root 6g, bush 7.5g, prairie fire rope 7.5g, deep fragrant 3.5g, white wine is appropriate.
The preparation method of orthopedics and traumatology astringing to arrest bleeding medicinal liquor is:
(1) take korean raspberry root decontamination, be cut into small pieces, explode to surface brown color with tung oil, take out, drain oil, cool;(2) by peach Benevolence decontamination, is placed in pot, and the salt solution (salt is 1:30 with the mass ratio of water) adding medicinal material weight 0.3 times stirs to parching, Take out;
(3) taking prairie fire rope, wide muscle rattan and deep fragrant decontamination, infiltration, chopping, be subsequently placed in frying pan, little fire is fried to savory Time, take out, dry in the air cool;
(4) by bush decontamination, clean, be placed in baking oven together with step (1) (2) (3) made medicinal material, dry, pulverized 60 Mesh sieve, is subsequently placed in pot, adds 30 degree of white wine of whole quality of medicinal materials 6 times, and big fire is boiled 15 minutes, finally closes fire and is cooled to often Temperature, pours in vial, seals, and after soaking 15 days, filters, removes the dregs of a decoction, obtain astringing to arrest bleeding medicinal liquor.
The clinical practice of test example 1 embodiment 5 gained orthopedics and traumatology astringing to arrest bleeding medicinal liquor:
386 example patients, wherein women 158 example is screened from hospital's orthopedics and traumatology outpatient service, the male sex 228 example, oldest 60 years old, minimum 5 years old age, 47.2 years old mean age.Diagnostic criteria: 1, have clear and definite trauma history;2, surface of a wound swelling pain, ring week property tenderness, or There are ecchymosis, deformity dysfunction;3, naked eyes are it can be seen that the dermatorrhagia worn by spur;4, X sheet display fracture site has gap Or sclerotin fracture.
Patient is randomly divided into two groups, experimental group and control group, two groups at aspects such as sex, age, the course of disease, the state of an illness without aobvious Write difference (P > 0.05), there is comparativity.Experimental group takes embodiment 5 products obtained therefrom, takes every day twice, each 1-2 two (having adjusted depending on concrete condition);Control group takes other medicine (routine such as GUZHE CUOSHANG JIAONANG, pseudo-ginseng tablet for curing fracture, synthetism are precious Medicine).During taking medicine, two groups of patients are carried out Continuous Observation, record symptom and change, after 50 days, carries out treatment results statistics.
Curative effect situation criterion: cure: swelling, pain and the clinical symptoms such as bleed, sign disappear, wound healing, merit Can recover, union;Effective: clinical symptoms, sign are obviously improved, surface of a wound part heals, and funtion part is recovered, and has poroma raw Become;Invalid: before and after treatment, sings and symptoms shows the most unchanged.
Treatment results is as shown in table 1.
1 liang of table group patient treatment outcome
As it can be seen from table 1 after treating 50 days, take the experimental group patient of embodiment 5 gained medicinal liquor, the number of cases of healing has 167 Example (62.8%), the patient that symptom is clearly better has 92 examples (34.6%), and experimental group total effective rate is 97.4%;Always having of control group Efficiency is 88.3%, therefore, it can show that experimental group medicinal liquor is good compared with control group medicament to the result for the treatment of of fracture.
The peach kernel that the present invention selects has promoting blood circulation effect;Wide muscle rattan have stimulate the circulation of the blood and cause the muscles and joints to relax, wind-expelling pain-stopping effect;Fall raw Root has promoting blood circulation and hemostasis, the effect of dispelling rheumatism;Prairie fire rope has hemostasis synthetism, myogenic detoxication;Deep perfume (or spice) have invigorate blood circulation logical Network, eliminating cold to stop pain;Bush has row blood and dissolving stasis, a swelling and pain relieving effect, every kind of medicine be both for fracture, patient with bone fracture symptom and select Select, multiple medicines use together, bone fracture must be played stasis-dispelling and pain-killing, promoting blood circulation and hemostasis, effect of synthetism myogenic.
It should be pointed out that, the detailed description of the invention more representational example that is the present invention, it is clear that the skill of the present invention Art scheme is not limited to above-described embodiment, it is also possible to have many variations.Those of ordinary skill in the art, the most public with present invention institute What what that open or according to file written description was undoubted obtained, all it is considered as this patent scope of the claimed.

Claims (1)

1. the preparation method of orthopedics and traumatology astringing to arrest bleeding medicinal liquor, is characterized in that, takes following bulk drugs: peach kernel 12g, wide muscle rattan 4.5g, Korean raspberry root 6g, bush 7.5g, prairie fire rope 7.5g, deep fragrant 3.5g, white wine is appropriate;Step is:
(1) take korean raspberry root decontamination, be cut into small pieces, explode to surface brown color with tung oil, take out, drain oil, cool;
(2) by peach kernel decontamination, being placed in pot, the salt solution (salt is 1:30 with the mass ratio of water) adding medicinal material weight 0.3 times stirs To parching, take out;
(3) taking prairie fire rope, wide muscle rattan and deep fragrant decontamination, infiltration, chopping, be subsequently placed in frying pan, little fire is fried to savory Time, take out, dry in the air cool;
(4) by bush decontamination, clean, be placed in baking oven together with step (1) (2) (3) made medicinal material, dry, pulverized 60 Mesh sieve, is subsequently placed in pot, adds 30 degree of white wine of whole quality of medicinal materials 6 times, and big fire is boiled 15 minutes, finally closes fire and is cooled to often Temperature, pours in vial, seals, and after soaking 15 days, filters, removes the dregs of a decoction, obtain astringing to arrest bleeding medicinal liquor.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511561A (en) * 2017-01-12 2017-03-22 李婷婷 Medicinal liquor capable of promoting fracture healing and preparation method thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
云南中草药整理组: "《云南中草药》", 30 September 2011, 云南人民出版社 *
张春玲等: "骨折的中药内治", 《中国实验方剂学杂志》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106511561A (en) * 2017-01-12 2017-03-22 李婷婷 Medicinal liquor capable of promoting fracture healing and preparation method thereof

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