CN104352843A - Tendon-relaxing and collateral-activating preparation for bone injury prognosis and preparation method of tendon-relaxing and collateral-activating preparation - Google Patents
Tendon-relaxing and collateral-activating preparation for bone injury prognosis and preparation method of tendon-relaxing and collateral-activating preparation Download PDFInfo
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Abstract
The invention discloses a tendon-relaxing and collateral-activating preparation for bone injury prognosis and a preparation method of the tendon-relaxing and collateral-activating preparation. The preparation is prepared from the following main raw materials in parts by weight: 6-18 parts of tabasheer, 5 to 12 parts of cuckoo, 3-6 parts of ferula asafoetida, 9-15 parts of cortex acanthopanacis, 10-16 parts of eucommia ulmoides, 4 to 10 parts of curly bristlethistle herb, 6-12 parts of scandent schefflera root, 8-12 parts of caulis spatholobi, 9-15 parts of gentiana macrophylla, 6-15 parts of rhizoma cyperi and 6-15 parts of ligusticum wallichii. The preparation is quick-acting, remarkable in treatment effect and low in treatment expense, and can relieve pain of patients.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to channels sootheing and network vessel quickening preparation and preparation method thereof after a kind of bone injury medicine.
Background technology
Leaving over ankylosis in various degree after union of fracture, is one of main sequela of fracture, very common in Orthopedic Clinical.The sequela of fracture more easily causes permanent lesion than nonunion or malunion; The damage of periarticular soft tissues, joint is fixed for a long time, and the mechanical load lacking motion and change, for the physiological stimulation of skeletal muscle complex, shows as chronic edema; Edema then causes muscle internal fibrillation and amyotrophy; This Fibrotic process makes muscle and non-physiologic adhesion occurs between skeleton and fascia, thus occurs the stiff of adjacent joints, answers early ambulant, functional exercise, active prevention.Concurrent ankylosis after union of fracture, when mainly fixing in early days or when exceeding the time limit to fix, also or under adopting the situations such as Bone traction overlong time, the joint that fracture site is adjacent lacks caused by suitable functional exercise, its pathological change is hematoma flesh, fibrosis, add and lack suitable early functional exercise, cause the extensive adhesion of periarticular tissue, ligament, degeneration, severe one even forms myositis ossificans.
Application publication number CN 101926867 A(application number 201010283288.X) Chinese patent literature disclose a kind of bone fracture recovering soup, it is made up of Radix Notoginseng, Radix Angelicae Sinensis, Semen Persicae, Flos Carthami, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Radix Dipsaci, the Cortex Eucommiae, eupolyphaga, Rhizoma Drynariae, Carapax et Plastrum Testudinis, Ramulus Cinnamomi and Radix Glycyrrhizae.Application publication number CN 103877556 A(application number 201410153894.8) Chinese patent literature disclose a kind of bone fracture Chinese medicinal ointment, the quality of its every kilograms of product consists of than formula: Rhizoma Chuanxiong 50-150g, Radix Dipsaci 50-150g, Radix Astragali 120-250g, Radix Angelicae Sinensis 50-150g, Caulis Spatholobi 50-150g, Radix Achyranthis Bidentatae 10-100g, Rhizoma Drynariae 10-100g, Radix Paeoniae Rubra 10-100g, Radix Paeoniae Alba 10-100g, Rhizoma Dioscoreae Septemlobae 10-60g, Rhizoma Zingiberis 10-60g, Rhizoma Et Radix Notopterygii 10-60g, Radix Angelicae Pubescentis 10-60g, Olibanum 10-60g, Myrrha 10-60g, Borneolum Syntheticum 10-60g, adjuvant: vaseline 500-800g, lanoline 30-120g, glycerol 10-60g, ethyl hydroxybenzoate 1-5g.Publication number CN 101642496A(application number 200810012748.8) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of bone injury diseases, it is mixed with by following raw materials according: cattle sunset 30g, Pheretima 30g, Radix Chimonanthi praecocis 30g, JUSHIMA 30g, Radix Aconiti Preparata 20g, Scolopendra 2, Scorpio 3g, Flos Carthami 80g, eupolyphaga 50g, Radix Saposhnikoviae 50g, Fructus Chaenomelis 50g, Rhizoma Et Radix Notopterygii 80g, Radix Angelicae Pubescentis 80g, Radix Clematidis 80g, Radix Notoginseng 80g, Rhizoma Atractylodis 50g, Radix Dipsaci 80g.
Solution conventional is at present that physical therapy adds functional exercise, although effectively, functional rehabilitation seems too slow, and curative effect is unsatisfactory.Although operation is loosened and can be solved a part of problem, postoperative wound has the possibility causing secondary adhesion, and painful large, and costly, patient is often reluctant to accept.
Summary of the invention
For the deficiencies in the prior art, the object of this invention is to provide channels sootheing and network vessel quickening preparation and preparation method thereof after a kind of bone injury medicine.Channels sootheing and network vessel quickening preparation instant effect after this bone injury medicine, evident in efficacy, reduction of patient is painful, and medical expense is low.
Technical scheme of the present invention is:
Channels sootheing and network vessel quickening preparation after bone injury medicine, takes off the primary raw material medicine stating weight proportion and is prepared from: Concretio Silicea Bambusae 6-18, Cuculus polioephalus 5-12, Resina Ferulae 3-6, Cortex Acanthopancis 9-15, Cortex Eucommiae 10-16, Herba Cardui Crispi 4-10, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6-12, Caulis Spatholobi 8-12, Radix Gentianae Macrophyllae 9-15, Rhizoma Cyperi 6-15, Rhizoma Chuanxiong 6-15.
Channels sootheing and network vessel quickening preparation after bone injury medicine, preferred scheme is, takes off the primary raw material medicine stating weight proportion and is prepared from: Concretio Silicea Bambusae 9-14, Cuculus polioephalus 7-9, Resina Ferulae 4-5.5, Cortex Acanthopancis 11-13, Cortex Eucommiae 12-14, Herba Cardui Crispi 6-9, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 7-11, Caulis Spatholobi 9-11, Radix Gentianae Macrophyllae 11-13, Rhizoma Cyperi 8-12, Rhizoma Chuanxiong 9-13.
Channels sootheing and network vessel quickening preparation after bone injury medicine, the scheme be more preferably is, takes off the primary raw material medicine stating weight proportion and is prepared from: Concretio Silicea Bambusae 11, Cuculus polioephalus 8, Resina Ferulae 5, Cortex Acanthopancis 12, the Cortex Eucommiae 13, Herba Cardui Crispi 7, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 9, Caulis Spatholobi 10, Radix Gentianae Macrophyllae 12, Rhizoma Cyperi 9, Rhizoma Chuanxiong 11.
Present invention also offers and channels sootheing and network vessel quickening preparation after aforementioned bone injury medicine is made the preparation method of pharmaceutically acceptable decoction, pill and powder.
The preparation method of described decoction is:
(1) get clean Radix Gentianae Macrophyllae to put into pot and fry 10-30 minute (preferably fry 22 minutes), spray vinegar, the consumption of vinegar is the consumption of the preferred vinegar of 1/10-1/3(of Radix Gentianae Macrophyllae weight is 1/4 of Radix Gentianae Macrophyllae weight), then fry 30-50 minute (preferably frying 38 minutes), take out, cool;
(2) Concretio Silicea Bambusae and Resina Ferulae are smashed to pieces be separately respectively charged in gauze bag, gauze bag is put into marmite, add water, the consumption of water is 8-12 times (consumption of preferred water is 10 times of the crude drug weight added) of the crude drug weight added, and soaks 1-2 hour (preferably soaking 1.6 hours);
(3) Cuculus polioephalus, Cortex Acanthopancis, the Cortex Eucommiae, Herba Cardui Crispi, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Caulis Spatholobi, Rhizoma Cyperi, Rhizoma Chuanxiong and step (1) gained Radix Gentianae Macrophyllae are joined in above-mentioned marmite, first boil to boiling with big fire, boil 40-70 minute (preferred little fire boils 50 minutes) with little fire afterwards, leach medicinal liquid;
(4) water (preferably the water of medical material gross weight added by 3.5 times amount) of medical material gross weight added by 3-5 times amount is joined surplusly have in the marmite of medicinal residues, first boil to boiling with big fire, to boil 25-50 minute (preferred little fire boils 32 minutes) with little fire afterwards, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, to obtain final product.
The preparation method of described pill is:
(1) get clean Radix Gentianae Macrophyllae to put into pot and fry 10-30 minute (preferably fry 22 minutes), spray vinegar, the consumption of vinegar is the consumption of the preferred vinegar of 1/10-1/3(of Radix Gentianae Macrophyllae weight is 1/4 of Radix Gentianae Macrophyllae weight), fry again 30-50 minute (preferably frying 38 minutes), taking-up cools, grind into powder, cross 100-140 mesh sieve (preferred mistake 120 mesh sieve), for subsequent use;
(2) get Resina Ferulae and add 0.8-1.2 times amount vinegar (preferably adding 1 times amount vinegar), vexed 20-55 minute (preferably vexed 40 minutes), put slow fire in pot and fry 30-45 minute (preferably frying 35 minutes), taking-up cools, grind into powder, cross 100-150 mesh sieve (preferred mistake 120 mesh sieve), for subsequent use;
(3) all the other the 9 taste medicines except Resina Ferulae and Radix Gentianae Macrophyllae are removed impurity, after drying, pulverize respectively and grind to form fine powder, cross 110-130 mesh sieve (preferred mistake 120 mesh sieve);
(4) step (1), step (2) and step (3) gained fine powder are fully mixed, refined honey is added in fine powder after mixing, the weight of refined honey is 0.8-1.6 times (weight of preferred refined honey is 1.2 times of fine powder gross weight) of fine powder gross weight, mixing, make pill, every ball weight is 0.3-0.6 gram (preferably every ball weight is 0.5 gram), dries and get final product.
The preparation method of described powder is:
(1) get Resina Ferulae and add 0.8-1.2 times amount vinegar (preferably adding 1 times amount vinegar), vexed 20-55 minute (preferably vexed 40 minutes), put slow fire in pot and fry 30-45 minute (preferably frying 35 minutes), taking-up cools, grind into powder, cross 150-180 mesh sieve (preferred mistake 170 mesh sieve), for subsequent use;
(2) all the other except Resina Ferulae 10 taste medicine is removed impurity, after drying, pulverize respectively and grind to form fine powder, cross 150-200 mesh sieve (preferred mistake 170 mesh sieve);
(3) step (1) and step (2) gained fine powder are fully mixed, sterile packaged, often wrap 4 grams.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Concretio Silicea Bambusae: base is former: be the dried block of juice in the stalks such as grass Chinese textile bamboo or schizostachyum chinense Rendle.The property of medicine: sweet, cold.GUIXIN, Liver Channel.Function cures mainly: clear heat and eliminate phlegm, cool heart arresting convulsion.For calentura coma, middle wind-phlegm fan, the hot diarrhea induced by fright of children's's expectorant, tic, night cry.
Cuculus polioephalus: base is former: be Ericaceae rhododendron Cuculus polioephalus, is used as medicine with root, leaf and flower.The property of medicine: root: sour, puckery, temperature, poisonous.Leaf, flower: sweet, sour are flat.Function cures mainly: root: wind-damp dispelling, blood circulation and promoting silt, hemostasis.For rheumatic arthritis, traumatic injury, amenorrhea; Traumatic hemorrhage is controlled in external.Flower, leaf: heat-clearing and toxic substances removing, preventing phlegm from forming and stopping coughing, antipruritic.For bronchitis, urticaria; Carbuncle is controlled in external.
Resina Ferulae: base is former: be the resin of samphire Ferula sinkiangensisK.M.Shen or Ferula fukanensis K.M.Shen.The property of medicine: bitter, pungent, temperature.Return spleen, stomach warp.Function cures mainly: removing food stagnancy, loose painful abdominal mass, parasite killing.For meat stagnation, Yu mass resulting from the blood stasis abdominal mass, mass in abdomen, abdominal pain due to worm stagnation.
Cortex Acanthopancis: base is former: be the dry root bark of Araliaceae acanthopanax gracilistylus.The property of medicine: pungent, bitter, temperature.Return liver, kidney channel.Function cures mainly: wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening.For rheumatic arthralgia, muscles and bones flaccidity is soft, children's's walking retardation in children, and body void is weak, edema, beriberi.
The Cortex Eucommiae: base is former: be the dry bark of the Eucommiaceae plant Cortex Eucommiae.The property of medicine: sweet, temperature.Return liver, kidney channel.Function cures mainly: invigorating the liver and kidney, and bone and muscle strengthening is antiabortive.For lumbago due to renal deficiency, muscles and bones is unable, blood leaking in gestation, frequent fetal movement, hypertension.
Herba Cardui Crispi: base is former: be herb or the root of feverfew Herba Cardui Crispi.The property of medicine: micro-hardship, flat.Return lung, bladder, liver three warp.Function cures mainly: dispel the wind, heat clearing away, dampness removing, cool the blood dissipate blood stasis.Control anemopyretic cold, phlegm-accumulating vertigo, wind heat arthralgia pain, skin urtication, urinary tract infection, chyluria, hematuria, leukorrhagia, traumatic injury congestive edema, furuncle swelling toxin, burn.
Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae): base is former: be root or the stem and leaf of Araliaceae schefflera arboricola.The property of medicine: micro-hardship, temperature.Return lung, kidney,liver,spleen four warp.Function cures mainly: expelling wind and removing dampness, promoting blood circulation and stopping pain.Dispelling the wind and dampness pathogens arthralgia pain, stomachache, injury and bone fracture, traumatic hemorrhage." the practical Chinese herbal medicine in Guangxi newly selects ": " promoting the circulation of QI to relieve pain, promoting blood circulation and detumescence, strengthening bone and muscle.Control acute rheumatic arthritis, stomachache, fracture, bruise, lumbago and skelalgia, paralysis.”
Caulis Spatholobi: base is former: be the rattan of leguminous plant spatholobus suberectus, Mucuna birdwoodiana, fragrant flower Moghania fluminalis(C. B. Clarke) Li rattan or bright leaf Moghania fluminalis(C. B. Clarke) Li rattan etc.Chemical analysis: fragrant flower Moghania fluminalis(C. B. Clarke) Li rattan is containing milletol.The property of medicine: bitter sweet, temperature." book on Chinese herbal medicine is new again ": " enter the heart, spleen two warp." function cures mainly: to invigorate blood circulation, relaxing muscles and tendons.Control soreness of waist and knee joint, paralysis and numbness, menoxenia.
Radix Gentianae Macrophyllae: base is former: be the dry root of gentianaceae plant Radix Gentianae Macrophyllae, gentiana straminea maxim, gentiana crassicaulis Duthie or Gentiana dahurica.The property of medicine: pungent, bitter, flat.Return stomach, liver, gallbladder meridian.Function cures mainly: wind-damp dispelling, clearing away damp-heat, stopping numbness pain.For rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, and day feeds hectic fever, and infantile malnutrition generates heat.
Rhizoma Cyperi: base is former: be the dry rhizome of sedge dried tuber.Chemical analysis: containing glucose 8.3 ~ 9.1%, fructose 1.0 ~ 1.7%, starch 40 ~ 41.1%, volatile oil 0.65 ~ 1.4%.Contain in volatile oil: nopinene, camphene, limonene, 1, 8-Cineole, cymol, Rhizoma Cyperi alkene, selinatriene, β-selinene, α-cyperone, β-cyperone, greenery terpenone, α-and β-rotunol, cyperol, isocyperol, epoxyguaine azulene, cyperolone, rotundone, kobusone and isokobusone.Root contains the material suppressing some fungi development.The property of medicine: pungent, micro-hardship, micro-sweet, flat.Return liver, spleen, tri-jiao channel.Function cures mainly: promoting QI circulation for relieving depression, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, breast gastral cavity painful abdominal mass is vexed, and colic of cold type is suffered from abdominal pain, distending pain of the breast, menoxenia, amenorrhea dysmenorrhea.
Rhizoma Chuanxiong: base is former: be the dry rhizome of samphire Rhizoma Chuanxiong.The property of medicine: pungent, temperature.Return liver, gallbladder, pericardium channel.Function cures mainly: blood-activating and qi-promoting, wind-expelling pain-stopping.For menoxenia. amenorrhea dysmenorrhea, mass in the abdomen is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
Channels sootheing and network vessel quickening preparation recipe science after bone injury medicine provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience.In addition, excellent results of the present invention also shows:
1, raw materials used cheap and easy to get, production cost is low, and medical expense is low;
2, instant effect, evident in efficacy;
3, have no side effect;
4, reduction of patient is painful.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1channels sootheing and network vessel quickening preparation after bone injury medicine, the primary raw material medicine getting following weight is prepared from: Concretio Silicea Bambusae 6g, Cuculus polioephalus 5g, Resina Ferulae 3g, Cortex Acanthopancis 9g, Cortex Eucommiae 10g, Herba Cardui Crispi 4g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6g, Caulis Spatholobi 8g, Radix Gentianae Macrophyllae 9g, Rhizoma Cyperi 6g, Rhizoma Chuanxiong 6g.
After bone injury medicine, the preparation method of channels sootheing and network vessel quickening preparation decoction is:
(1) get clean Radix Gentianae Macrophyllae and put into pot stir-fry 10 minutes, spray vinegar, the consumption of vinegar is 1/10 of Radix Gentianae Macrophyllae weight, then fries 30 minutes, takes out, cools;
(2) Concretio Silicea Bambusae and Resina Ferulae are smashed to pieces separately and be respectively charged in gauze bag, gauze bag is put into marmite, adds water, the consumption of water is that 8 times of the crude drug weight added soak 1 hour;
(3) Cuculus polioephalus, Cortex Acanthopancis, the Cortex Eucommiae, Herba Cardui Crispi, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Caulis Spatholobi, Rhizoma Cyperi, Rhizoma Chuanxiong and step (1) gained Radix Gentianae Macrophyllae are joined in above-mentioned marmite, first boil to boiling with big fire, boil 40 minutes with little fire afterwards, leach medicinal liquid;
(4) water of medical material gross weight added by 3 times amount is joined surplusly have in the marmite of medicinal residues, first boil to boiling with big fire, boil 25 minutes with little fire afterwards, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, to obtain final product.
Decoction instructions of taking of the present invention: every day twice, each 300mL(is warm).
embodiment 2channels sootheing and network vessel quickening preparation after bone injury medicine, the primary raw material medicine getting following weight is prepared from: Concretio Silicea Bambusae 18g, Cuculus polioephalus 12g, Resina Ferulae 6g, Cortex Acanthopancis 15g, Cortex Eucommiae 16g, Herba Cardui Crispi 10g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 12g, Caulis Spatholobi 12g, Radix Gentianae Macrophyllae 15g, Rhizoma Cyperi 15g, Rhizoma Chuanxiong 15g.
After bone injury medicine, the preparation method of channels sootheing and network vessel quickening preparation pill is:
(1) get clean Radix Gentianae Macrophyllae and put into pot stir-fry 22 minutes, spray vinegar, the consumption of vinegar is 1/4 of Radix Gentianae Macrophyllae weight, then fries 38 minutes, and taking-up cools, and grinds into powder, crosses 120 mesh sieves, for subsequent use;
(2) get Resina Ferulae and add 1 times amount vinegar, vexed 40 minutes, put slow fire in pot and fry 35 minutes, taking-up cools, and grinds into powder, crosses 120 mesh sieves, for subsequent use;
(3) all the other the 9 taste medicines except Resina Ferulae and Radix Gentianae Macrophyllae are removed impurity, after drying, pulverize respectively and grind to form fine powder, cross 120 mesh sieves;
(4) step (1), step (2) and step (3) gained fine powder are fully mixed, add refined honey by the fine powder after mixing, the weight of refined honey is 1.2 times of fine powder gross weight, and mixing, make pill, every ball weight is 0.5 gram, dries and get final product.
model case one:honest and just XX, man, patient 58 years old.Left foot thumb was subject to collision.To be admitted to hospital bat X-ray, to be diagnosed as thumb fissure fracture.Doctor's suggestion is lain up, lifting affected limb, oral bone setting tablet, JIEGU QILI PIAN.Again clap X mating plate after three months, fracture heals substantially, but left foot thumb joint function limitation.Through functional exercise after a while, Drug therapy is coordinated all not feel any better.Take channels sootheing and network vessel quickening preparation pill after the present embodiment gained bone injury medicine, every day 3 times, each 8, warm water takes.Take 5 days, symptom obviously alleviates.Continue to take 3 days, left foot thumb joint functional rehabilitation, recovery from illness.
embodiment 3channels sootheing and network vessel quickening preparation after bone injury medicine, the primary raw material medicine getting following weight is prepared from: Concretio Silicea Bambusae 9g, Cuculus polioephalus 7g, Resina Ferulae 4g, Cortex Acanthopancis 11g, Cortex Eucommiae 12g, Herba Cardui Crispi 6g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 7g, Caulis Spatholobi 9g, Radix Gentianae Macrophyllae 11g, Rhizoma Cyperi 8g, Rhizoma Chuanxiong 9g.
After bone injury medicine, the preparation method of channels sootheing and network vessel quickening preparation powder is:
(1) get Resina Ferulae and add 1 times amount vinegar, vexed 40 minutes, put slow fire in pot and fry 35 minutes, taking-up cools, and grinds into powder, crosses 170 mesh sieves, for subsequent use;
(2) all the other except Resina Ferulae 10 taste medicine is removed impurity, after drying, pulverize respectively and grind to form fine powder, cross 170 mesh sieves;
(3) step (1) and step (2) gained fine powder are fully mixed, sterile packaged, often wrap 4 grams.
model case two:king XX, man, 35 years old.On October 21st, 2011 is wounded by minibus by bike.Laboratory examination result: right knee joint Nei Guo bone fracture.Operative site three place, about foot and heel, internal fixation steel plate one piece, steel nail 13, the while in hospital lies up always, checks that bone is fixing normal through X-ray.Wound epidermis substantially heals and leaves hospital.Reveal existing edema, hook in foot five toe, heel can not land.Cardinal symptom: have congestion lump, ankylosis inside right lower limb knee joint, medial femoral swelling, bending pain, oneself can only be curved about 80 degree.It is the complication ankylosis caused by long-term internal fixtion.Use stretches that muscle is loose, active wet goods medicine, is showed no improvement.Take channels sootheing and network vessel quickening preparation powder after the present embodiment gained bone injury medicine, every day twice, each 4 grams, boiled water is taken after mixing it with water.Take 4 days, symptom obviously alleviates.Continue to take 5 days, all transference cures, joint function recovery, without swelling pain, recovery from illness.
embodiment 4channels sootheing and network vessel quickening preparation after bone injury medicine, the primary raw material medicine getting following weight is prepared from: Concretio Silicea Bambusae 14g, Cuculus polioephalus 9g, Resina Ferulae 5.5g, Cortex Acanthopancis 13g, Cortex Eucommiae 14g, Herba Cardui Crispi 9g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 11g, Caulis Spatholobi 11g, Radix Gentianae Macrophyllae 13g, Rhizoma Cyperi 12g, Rhizoma Chuanxiong 13g.
After bone injury medicine, the preparation method of channels sootheing and network vessel quickening preparation decoction is:
(1) get clean Radix Gentianae Macrophyllae and put into pot stir-fry 30 minutes, spray vinegar, the consumption of vinegar is 1/3 of Radix Gentianae Macrophyllae weight, then fries 50 minutes, takes out, cools;
(2) Concretio Silicea Bambusae and Resina Ferulae are ground separately and be respectively charged in gauze bag, gauze bag is put into marmite, adds water, the consumption of water is 12 times of the crude drug weight added, and soaks 2 hours;
(3) Cuculus polioephalus, Cortex Acanthopancis, the Cortex Eucommiae, Herba Cardui Crispi, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Caulis Spatholobi, Rhizoma Cyperi, Rhizoma Chuanxiong and step (1) gained Radix Gentianae Macrophyllae are joined in above-mentioned marmite, first boil to boiling with big fire, boil 70 minutes with little fire afterwards, leach medicinal liquid;
(4) water of medical material gross weight added by 5 times amount is joined surplusly have in the marmite of medicinal residues, first boil to boiling with big fire, boil 50 minutes with little fire afterwards, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, to obtain final product.
model case three:king XX, female, 29 years old.Hurt right ring finger at work the year before, to connecting palm place fracture below nameless middle joint, bone disconnects, and surface is intact, and skin and meat do not have hemorrhage, swell exactly, advises, have an operation through doctor.Interal fixation is nailed in finger, after leaving hospital, nameless function of joint is limited, stretch in the wrong all very difficult, can not stretch, curvedly also can only be bent to 90 degree, through the exercise in the thorough heart of pain many times, all lose effect, after 1 year, film making in namely first more than ten days checks that bone heals has got internal fixtion (steel plate) in hospital, finds or can not stretch in the wrong.Use the drug ineffective such as channels sootheing and network vessel quickening wine.Take channels sootheing and network vessel quickening preparation decoction after the present embodiment gained bone injury medicine, every day twice, each 300mL(decoction being taken warmly).Take 3 days, symptom is clearly better.Continue to take 5 days, the third finger is stretched and is bent freely, recovery from illness.
embodiment 5channels sootheing and network vessel quickening preparation after bone injury medicine, the primary raw material medicine getting following weight is prepared from: Concretio Silicea Bambusae 11g, Cuculus polioephalus 8g, Resina Ferulae 5g, Cortex Acanthopancis 12g, Cortex Eucommiae 13g, Herba Cardui Crispi 7g, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 9g, Caulis Spatholobi 10g, Radix Gentianae Macrophyllae 12g, Rhizoma Cyperi 9g, Rhizoma Chuanxiong 11g.
After bone injury medicine, the preparation method of channels sootheing and network vessel quickening preparation decoction is:
(1) get clean Radix Gentianae Macrophyllae and put into pot stir-fry 22 minutes, spray vinegar, the consumption of vinegar is 1/4 of Radix Gentianae Macrophyllae weight, then fries 38 minutes, takes out, cools;
(2) Concretio Silicea Bambusae and Resina Ferulae are ground separately and be respectively charged in gauze bag, gauze bag is put into marmite, adds water, the consumption of water is 10 times of the crude drug weight added, and soaks 1.6 hours;
(3) Cuculus polioephalus, Cortex Acanthopancis, the Cortex Eucommiae, Herba Cardui Crispi, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Caulis Spatholobi, Rhizoma Cyperi, Rhizoma Chuanxiong and step (1) gained Radix Gentianae Macrophyllae are joined in above-mentioned marmite, first boil to boiling with big fire, boil 50 minutes with little fire afterwards, leach medicinal liquid;
(4) water of medical material gross weight added by 3.5 times amount is joined surplusly have in the marmite of medicinal residues, first boil to boiling with big fire, boil 32 minutes with little fire afterwards, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, to obtain final product.
test example 1the clinical practice of channels sootheing and network vessel quickening preparation decoction after bone injury medicine: in November ,-2012 in June, 2011, the 286 stiff patients of routine bone injury medicine posterior joint are screened in 6 hospitals, wherein male 152 example, women 134 example, oldest 65 years old, minimum 19 years old of age, 40.5 years old mean age, the course of disease 4 months-2 years, average course of disease 8 months.Be divided into two groups at random, experimental group and matched group.Experimental group women 66 example, male 77 example, age 19-65 year, 40.5 years old mean age, the course of disease 4 months-2 years, average course of disease 8 months.Matched group women 68 example, male 75 example, age 19-65 year, 40.5 years old mean age, the course of disease 4 months-2 years, average course of disease 8 months.Between two groups of patients, the aspect such as sex, age, course of disease compares, and no significant difference (P > 0.05), has comparability.Experimental group uses embodiment 5 products obtained therefrom, every day twice (warm), each 300mL.Matched group uses the stiff medicine of conventional therapy bone injury medicine posterior joint (as panchrest plaster, damage rheumatism plaster, stretch that muscle is loose, active wet goods).Curative effect situation criterion: cure: periarticular swelling disappears, and range of motion is identical with strong side; Effective: periarticular swelling disappears substantially, range of motion reaches strong side 80%, and normal physiological function is substantially unaffected; Take a turn for the better: periarticular swelling has and necessarily alleviates, and range of motion reaches strong side 60% ~ 80%, and normal physiological function has certain influence; Invalid: periarticular swelling degree, range of motion and function are not improved before all comparatively treating.Total effectively comprising cures and effective.Treat result after 10 days as shown in table 1.
Table 1: take the stiff patient treatment outcome of embodiment 5 product bone injury medicine posterior joint
As can be seen from Table 1, after using embodiment 5 gained bone injury medicine, the experimental group of channels sootheing and network vessel quickening preparation decoction only has 1 people invalid, and total effective rate reaches 97.90%.And matched group has nearly 25 people invalid, total effective rate only has 61.54%.Test shows, the successful of experimental group is better than matched group.
Concretio Silicea Bambusae clear heat and eliminate phlegm in side, cool heart arresting convulsion.Cuculus polioephalus wind-damp dispelling, blood circulation and promoting silt, hemostasis.Resina Ferulae removing food stagnancy, loose painful abdominal mass, parasite killing.Cortex Acanthopancis, Cortex Eucommiae invigorating the liver and kidney, bone and muscle strengthening.Herba Cardui Crispi dispels the wind, heat clearing away, dampness removing, cool the blood dissipate blood stasis.Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) expelling wind and removing dampness, promoting blood circulation and stopping pain.Caulis Spatholobi is invigorated blood circulation, relaxing muscles and tendons.Radix Gentianae Macrophyllae wind-damp dispelling, clearing away damp-heat, stopping numbness pain.Rhizoma Cyperi promoting QI circulation for relieving depression.Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping.All medicines share, blood circulation promoting and blood stasis dispelling, pain relieving, channels sootheing and network vessel quickening, expelling wind and removing dampness, and to the contracture of muscle arteries and veins, the disease of joint joint stuffiness obtains good therapeutic effect, to the recovery comparatively satisfaction of function of joint.By clinical observation, after bone injury medicine, channels sootheing and network vessel quickening preparation decoction is evident in efficacy.
Finally it should be noted that, embodiment is the detailed description of the invention of optimum of the present invention, be not limited to the present invention, although with reference to previous embodiment to invention has been detailed description, for a person skilled in the art, it still can be modified to the technical scheme described in foregoing embodiments, or carries out equivalent replacement to wherein portion of techniques feature.Within the spirit and principles in the present invention all, any amendment done, equivalent replacement, improvement etc., all should be included within protection scope of the present invention.
Claims (10)
1. channels sootheing and network vessel quickening preparation after bone injury medicine, is characterized in that, takes off the primary raw material medicine stating weight proportion and is prepared from: Concretio Silicea Bambusae 6-18, Cuculus polioephalus 5-12, Resina Ferulae 3-6, Cortex Acanthopancis 9-15, Cortex Eucommiae 10-16, Herba Cardui Crispi 4-10, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 6-12, Caulis Spatholobi 8-12, Radix Gentianae Macrophyllae 9-15, Rhizoma Cyperi 6-15, Rhizoma Chuanxiong 6-15.
2. channels sootheing and network vessel quickening preparation after bone injury medicine according to claim 1, is characterized in that, takes off the primary raw material medicine stating weight proportion and is prepared from: Concretio Silicea Bambusae 9-14, Cuculus polioephalus 7-9, Resina Ferulae 4-5.5, Cortex Acanthopancis 11-13, Cortex Eucommiae 12-14, Herba Cardui Crispi 6-9, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 7-11, Caulis Spatholobi 9-11, Radix Gentianae Macrophyllae 11-13, Rhizoma Cyperi 8-12, Rhizoma Chuanxiong 9-13.
3. channels sootheing and network vessel quickening preparation after bone injury medicine according to claim 1, is characterized in that, takes off the primary raw material medicine stating weight proportion and is prepared from: Concretio Silicea Bambusae 11, Cuculus polioephalus 8, Resina Ferulae 5, Cortex Acanthopancis 12, the Cortex Eucommiae 13, Herba Cardui Crispi 7, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae) 9, Caulis Spatholobi 10, Radix Gentianae Macrophyllae 12, Rhizoma Cyperi 9, Rhizoma Chuanxiong 11.
4., according to channels sootheing and network vessel quickening preparation after the arbitrary described bone injury medicine of claim 1-3, it is characterized in that, channels sootheing and network vessel quickening preparation after this bone injury medicine is made pharmaceutically acceptable decoction, pill and powder.
5. the preparation method of channels sootheing and network vessel quickening preparation after bone injury medicine according to claim 4, it is characterized in that, the preparation method of described decoction is:
(1) get clean Radix Gentianae Macrophyllae to put into pot and fry 10-30 minute (preferably fry 22 minutes), spray vinegar, the consumption of vinegar is the consumption of the preferred vinegar of 1/10-1/3(of Radix Gentianae Macrophyllae weight is 1/4 of Radix Gentianae Macrophyllae weight), then fry 30-50 minute (preferably frying 38 minutes), take out, cool;
(2) Concretio Silicea Bambusae and Resina Ferulae are ground separately be respectively charged in gauze bag, gauze bag is put into marmite, add water, the consumption of water is 8-12 times (consumption of preferred water is 10 times of the crude drug weight added) of the crude drug weight added, and soaks 1-2 hour (preferably soaking 1.6 hours);
(3) Cuculus polioephalus, Cortex Acanthopancis, the Cortex Eucommiae, Herba Cardui Crispi, Radix Schefflerae Arboricolae (Caulis et Folium Schefflerae Arboricolae), Caulis Spatholobi, Rhizoma Cyperi, Rhizoma Chuanxiong and step (1) gained Radix Gentianae Macrophyllae are joined in above-mentioned marmite, first boil to boiling with big fire, boil 40-70 minute (preferred little fire boils 50 minutes) with little fire afterwards, leach medicinal liquid;
(4) water (preferably the water of medical material gross weight added by 3.5 times amount) of medical material gross weight added by 3-5 times amount is joined surplusly have in the marmite of medicinal residues, first boil to boiling with big fire, to boil 25-50 minute (preferred little fire boils 32 minutes) with little fire afterwards, leach medicinal liquid;
(5) step (3) and step (4) gained medicinal liquid are merged, to obtain final product.
6. the preparation method of channels sootheing and network vessel quickening preparation after bone injury medicine according to claim 4, it is characterized in that, the preparation method of described pill is:
(1) get clean Radix Gentianae Macrophyllae to put into pot and fry 10-30 minute (preferably fry 22 minutes), spray vinegar, the consumption of vinegar is the consumption of the preferred vinegar of 1/10-1/3(of Radix Gentianae Macrophyllae weight is 1/4 of Radix Gentianae Macrophyllae weight), fry again 30-50 minute (preferably frying 38 minutes), taking-up cools, grind into powder, cross 100-140 mesh sieve (preferred mistake 120 mesh sieve), for subsequent use;
(2) get Resina Ferulae and add 0.8-1.2 times amount vinegar (preferably adding 1 times amount vinegar), vexed 20-55 minute (preferably vexed 40 minutes), put slow fire in pot and fry 30-45 minute (preferably frying 35 minutes), taking-up cools, grind into powder, cross 100-150 mesh sieve (preferred mistake 120 mesh sieve), for subsequent use;
(3) all the other the 9 taste medicines except Resina Ferulae and Radix Gentianae Macrophyllae are removed impurity, after drying, pulverize respectively and grind to form fine powder, cross 110-130 mesh sieve (preferred mistake 120 mesh sieve);
(4) step (1), step (2) and step (3) gained fine powder are fully mixed, refined honey is added in fine powder after mixing, the weight of refined honey is 0.8-1.6 times (weight of preferred refined honey is 1.2 times of fine powder gross weight) of fine powder gross weight, mixing, make pill, every ball weight is 0.3-0.6 gram (preferably every ball weight is 0.5 gram), dries and get final product.
7. the preparation method of channels sootheing and network vessel quickening preparation after bone injury medicine according to claim 4, it is characterized in that, the preparation method of described powder is:
(1) get Resina Ferulae with vinegar, vexed 20-55 minute (preferably vexed 40 minutes), put in pot and fry with slow fire, taking-up cools, and grinds into powder, crosses 150-180 mesh sieve (preferred mistake 170 mesh sieve), for subsequent use;
(2) all the other except Resina Ferulae 10 taste medicine is removed impurity, after drying, pulverize respectively and grind to form fine powder, sieve;
(3) step (1) and step (2) gained fine powder are fully mixed, sterile packaged, often wrap 4 grams.
8. the preparation method of channels sootheing and network vessel quickening preparation powder after bone injury medicine according to claim 7, is characterized in that, in step (1) consumption of vinegar be the 0.8-1.2 of Resina Ferulae weight doubly (consumption of preferred vinegar is 1 times of Resina Ferulae weight).
9. the preparation method of channels sootheing and network vessel quickening preparation powder after bone injury medicine according to claim 7, is characterized in that, fries 30-45 minute (preferably frying 35 minutes) in step (1) mid-pot with slow fire.
10. the preparation method of channels sootheing and network vessel quickening preparation powder after bone injury medicine according to claim 7, is characterized in that, crosses 150-200 mesh sieve (preferred mistake 170 mesh sieve) in step (2).
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| CN106109806A (en) * | 2016-07-13 | 2016-11-16 | 夏放军 | A kind of promoting blood circulation to remove obstruction in the collateral Chinese medicinal liquor and preparation method thereof |
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