CN102872420B - Medicine for treating rheumatic arthritis and preparation method thereof - Google Patents

Medicine for treating rheumatic arthritis and preparation method thereof Download PDF

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CN102872420B
CN102872420B CN201210394974.3A CN201210394974A CN102872420B CN 102872420 B CN102872420 B CN 102872420B CN 201210394974 A CN201210394974 A CN 201210394974A CN 102872420 B CN102872420 B CN 102872420B
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parts
medicine
rhizoma
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rheumatic arthritis
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CN102872420A (en
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李爱云
李翠霞
于慧玲
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Rudong Xinyu Technology Park Co Ltd
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Abstract

The invention discloses a medicine for treating rheumatic arthritis, and a preparation method thereof, belonging to the field of traditional Chinese medicine. The active ingredients of medicine comprise the raw materials in parts by weight: 12-18 parts of tinospora sinensis merr, 12-18 parts of lanatechead saussurea herb with flower, 15-30 parts of himalayan teasel root, 10-20 parts of pawpaws, 15-30 parts of FlemingiaphilippinensisMerr.etRolfe, 10-20 parts of ligusticum wallichii, 18-35 parts of paris polyphylla, 18-35 parts of scorpio, 12-18 parts of rhizoma curcumae, 10-20 parts of nidus vespae, 18-35 parts of cortex acanthopanacis and 10-16 parts of folium artemisiae argyi. The medicine has the effects of dispelling wind and eliminating dampness, eliminating cold to stop pain, promoting blood circulation to remove blood stasis, relieving rigidity of muscles and activating collaterals as well as reinforcing qi and nourishing blood, is good in absorption effect, definite in effect, safe, reliable and free from toxic and side effects, achieves the aim of treating both symptoms and root causes, and has good treatment effect on the rheumatic arthritis.

Description

A kind of medicine for the treatment of rheumatic arthritis and preparation method thereof
Affiliated technical field
The present invention relates to the field of Chinese medicines, be specifically related to a kind of medicine for the treatment of rheumatic arthritis and preparation method thereof.
Background technology
Rheumatic arthritis be a kind of take joint non-infectious inflammation as main systemic autoimmune disease, can repeatedly show effect and involve heart.Clinical miserable take joint and muscle migration, heavily work, pain is as feature, belongs to allergic disease.Rheumatic arthritis is the modal a kind of clinical disease of rheumatic fever, and rheumatic arthritis onset is more anxious, and mainly with febris acuta and arthralgia onset, typical case's performance is slight or moderate heating, migratory polyarthritis, and the Yi great joint, joint of getting involved is main.Start to invade and joint of the lower extremity person accounts for 85%, knee joint and ankle joint are the most common.Secondly be shoulder, elbow and wrist, the little joint of hands and foot is rare, arthropathy is multiple and migration, commonly be transferred to another joint by a joint, local joint inflammation is obvious, that performance has is red, swollen, hot, bitterly, tenderness and limitation of activity, persistent period is not long, be everlasting in a few days and disappear voluntarily, do not stay sequela, but Chang Fanfu outbreak.Atypical patient only has arthralgia and without the performance of other inflammation, myocarditis can occur even leaves over valve disorder if active rheumatism affects heart.
At present, not yet completely clear and definite for the mechanism of rheumatism, modern medicine to it also without good prevention and treatment method.But motherland's medical science has obvious advantage aspect the preventing and treating of rheumatism.The traditional Chinese medical science thinks, the exopathogen invasion and attack human bodies such as wind, cold, wet, heat, impatency meridians, QI and blood can not pass unimpeded, cause muscles and bones, joint etc. ache, numb, weighing, activities adverse, even arthroncus is scorching hot, so that stagnation of QI and blood may bring about pain."Nei Jing" is thought, plain body deficiency of qi and blood, and wind, cold, wet three gas heterozygosis are invaded human body in an opponent's defence, and multiple abscess muscles and bones blood vessels, fight and tie in joint, are the Etiological pathogenesis of numbness disease.So, just this pathogenetic external condition of heresy that wind and cold is damp and hot, and insufficiency of vital energy and blood, battalion defends to lack of proper care and is only the intrinsic factor of primary disease.The invention provides a kind of medicine for the treatment of rheumatic arthritis, it is take functions dispelling wind and clearing away cold, removing dampness, benefiting QI for activating blood circulation dredging collateral as rule for the treatment of, and in solution this type for the treatment of by Chinese herbs in the past, effect is obvious not, the slower problem that takes effect, effective, instant effect, there is effect remarkable, the advantage that drug effect is definite.
Summary of the invention
The invention provides a kind of medicine for the treatment of rheumatic arthritis and preparation method thereof, medicine of the present invention can bone and muscle strengthening, invigorating the liver and kidney, make local vascular dilation, blood fortune strengthens, metabolism strengthens, immunity improves, thereby makes pain relief, play strengthening the body resistance, relaxing muscles and tendons and activating QI and blood in the collateral, the removing dampness of dispeling the wind, enrich blood invigorate blood circulation, the effect of reducing swelling and alleviating pain.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a medicine for rheumatic arthritis, raw material composition and the parts by weight of making described effective ingredient are:
10~20 parts of 15~30 portions of Fructus Chaenomeliss of 12~18 parts of Radix Dipsacis of 12~18 parts of Herba Saussureae Involuerataes of Herba Lycopodii
18~35 parts of 18~35 portions of Scorpios of 10~20 parts of Rhizoma Paridis of 15~30 parts of Rhizoma Chuanxiongs of Radix Flemingiae Philippinensis
10~16 parts of 18~35 portions of Folium Artemisiae Argyis of 10~20 parts of Cortex Acanthopanciss of 12~18 parts of Nidus Vespae of Rhizoma Curcumae.
Raw material composition and the parts by weight of making described effective ingredient are:
13~18 parts of 20~25 portions of Fructus Chaenomeliss of 14~17 parts of Radix Dipsacis of 14~17 parts of Herba Saussureae Involuerataes of Herba Lycopodii
22~28 parts of 22~28 portions of Scorpios of 13~18 parts of Rhizoma Paridis of 20~25 parts of Rhizoma Chuanxiongs of Radix Flemingiae Philippinensis
12~15 parts of 22~28 portions of Folium Artemisiae Argyis of 13~18 parts of Cortex Acanthopanciss of 14~17 parts of Nidus Vespae of Rhizoma Curcumae.
Raw material composition and the parts by weight of making described effective ingredient are:
16 parts of 23 portions of Fructus Chaenomeliss of 15 parts of Radix Dipsacis of 15 parts of Herba Saussureae Involuerataes of Herba Lycopodii
25 parts of 25 portions of Scorpios of 16 parts of Rhizoma Paridis of 23 parts of Rhizoma Chuanxiongs of Radix Flemingiae Philippinensis
14 parts of 25 portions of Folium Artemisiae Argyis of 16 parts of Cortex Acanthopanciss of 15 parts of Nidus Vespae of Rhizoma Curcumae.
Treat a preparation method for the medicine of rheumatic arthritis, comprise following processing step:
(1) by each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process after mix homogeneously, porphyrize, crosses 120 order fine powders, for subsequent use.
(2) add in container after remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis are mixed homogeneously with Radix Flemingiae Philippinensis, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, Folium Artemisiae Argyi, add the water of 8 times of amounts, extract 2~3 hours, filter taking liquid; In remaining residue, add again the water of 6 times of amounts, extract 1~2 hour, filter taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of relative density 1.10~1.15 at 60 ℃, drying under reduced pressure.
(3) add step (2) to make mix homogeneously in thick paste gained fine powder in step (1), in 50~60 ℃ dry after, be ground into 120 object medicated powder, obtain the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant to be prepared into various pharmaceutical formulations.
The property of medicine of the present invention's Chinese medicine used is as follows:
Herba Lycopodii: hardship, cool.Return liver, spleen channel.There is expelling wind and removing dampness, effect of relaxing muscles and tendons and activating QI and blood in the collateral.For rheumatic ostalgia, grain contracture, fracture, traumatic injury." treasure-house " carries: " strangle wise sweet in the mouth, hardship, pungent, effect is controlled wind heat, plague fever while removing, and effect is slow, can be in harmonious proportion and occlusion disorder, controls ageing diseases, rheumatism.”
Herba Saussureae Involueratae: warm in nature, lightly seasoned acid, nontoxic.Enter liver,spleen,kidney three warps.There are except cold tonifying YANG, regulating menstruation, effect of hemostasis." Chinese Herbal Medicine in Xinjiang handbook " carries: " restore menstrual flow and invigorate blood circulation, bone and muscle strengthening, promotes uterine contraction.Treating rheumatic arthritis, women's cold and pain in the lower abdomen, amenorrhea, placenta retention, measles without adequate eruption, lung cold cough, sexual impotence.”
Radix Dipsaci: bitter in the mouth, pungent, slightly warm in nature.Return liver, kidney channel.There is invigorating the liver and kidney; Bone and muscle strengthening, blood circulation regulating, continuous injured, only effect of metrorrhagia.For aching pain in waist and back, podomere flaccidity syndrome and arthralgia syndrome, fall flutter wound, damage muscle folding bone, red, metrorrhagia is leaked in fetal movement, seminal emission, leukorrhagia, carbuncle skin ulcer are swollen." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " meridians determine in tonifying liver, bone and muscle strengthening, and only in warp, (muscles and bones) ached, antiabortive, controls married woman leucorrhea, tissue regeneration promoting blood, and removing blood stasis with potent drugs blood, the stillborn fetus that falls, the cough-relieving hemoptysis of coughing, controls red white turbid urine.”
Fructus Chaenomelis: property is put down, is slightly cold, sweet in the mouth.Return liver, spleen channel.Have suppressing the hyperactive liver relaxing muscles and tendons, effect of stomach function regulating removing dampness, swells and ache for rheumatic arthralgia, the heavy pain of waist knee joint acid, the contracture of muscle arteries and veins, beriberi.Fructus Chaenomelis has good relaxing muscles and tendons and activating QI and blood in the collateral effect, and energy removing dampness, by dispelling the wind and dampness pathogens arthralgia pain is commonly used, and particularly key medicine of muscle arteries and veins contracture person." book on Chinese herbal medicine newly organized " carries: " blood be that heat is compeled, myospasm and pain, and gas is humidity hysteresis, and muscular atonia is and soft, and Fructus Chaenomelis removing heat from blood is received and is taken off, therefore can and control.”
Radix Flemingiae Philippinensis: sweet, puckery flat.Return liver, kidney channel.There is relaxing muscles and tendons and activating QI and blood in the collateral, effect of strong waist knee joint.Dispelling the wind and dampness pathogens osteodynia, lumbar muscle strain, son foot is aching and limp, and osteopatia sprains etc., also can treat beriberi." medical material compilation of data " carries: " curing rheumatism, pain relieving.”
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.There is blood-activating and qi-promoting, effect of wind-expelling pain-stopping.Be used for pacifying nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia." Japan hanako materia medica " carries: " control a wind cutting, all gas, all strains, all blood, mend five kinds of over strain, and strengthening bone and muscle, adjusts many arteries and veins, and broken crux stagnated blood, supports fresh blood, puts on flesh.”
Rhizoma Paridis: be slightly cold, hardship.Return Liver Channel.There is heat-clearing and toxic substances removing, reducing swelling and alleviating pain, effect of cool liver arresting convulsion.Too fat to move for furuncle, laryngopharynx swelling and pain, venom, falls and flutters the pain of injury, convulsion with spasms." book on Chinese herbal medicine converges and says " carries: " Rhizoma Paridis, removing heat from blood removes wind, separates the medicine of carbuncle poison also.”
Scorpio: pungent, flat; Poisonous.Return Liver Channel.There is endogenous wind stopping spasmolytic, dispersing pathogen accumulation, effect of removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula." king Chinese catalpa medicine solution " carries: " wear muscle deep, by the wet wind that removes.”
Rhizoma Curcumae: pungent, bitter, temperature.Return liver, spleen channel.There is removing blood stasis, effect of promoting the circulation of QI to relieve pain." medicine justice " carries: " fluffy art acrid in the mouth is strong, specializes in the blood in gas, and the main removing mass heavily fortified point that disappears, removes to gather addiction piece, and amenorrhea blood stasis, flutters report pain.”
Nidus Vespae: sweet, flat.Return stomach warp.Dispel the wind, counteracting toxic substances, parasite killing, pain relieving, antianaphylactic effect." choosing of Simao, Yunnan Chinese herbal medicine " carries: " relaxing muscles and tendons and activating QI and blood in the collateral, method rheumatism, diuresis.Treating rheumatic arthritis, waist knee joint arthralgia chiefly caused by damp pathogen, oedema due to nephritis.”
Cortex Acanthopancis: pungent, bitter, temperature.Return liver, kidney channel.There is wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, effect of the arteries and veins of invigorating blood circulation., the children's walking retardation in children soft for anemofrigid-damp arthralgia, lumbocrural pain, muscles and bones flaccidity, body void are frail, traumatic injury, fracture, edema, beriberi, uncontrolled urination are itched." detailed outline " carries: " dispelling the wind and dampness pathogens flaccidity syndrome and arthralgia syndrome, strengthening bone and muscle.”
Folium Artemisiae Argyi: pungent, bitter, temperature; Slightly poisonous.Return liver,spleen,kidney warp.There is dispersing cold for relieving pain, effect of warming the meridian for stopping bleeding.Conventional dispelling the wind and dampness pathogens arthromyodynia, arthralgia." detailed outline " carries: " warming middle-JIAO, by cold, dehumidifying.”
The present invention, according to the theory of traditional Chinese medical science the body resistance strengthening and constitution consolidating, blood circulation promoting and blood stasis dispelling, develops meticulously.In side, all medicines share, and to rheumatic arthritis local pain, swelling, the muscle arteries and veins stasis of blood is stagnant, numb limbs and tense tendons, and soreness of waist and knee joint etc., can play relaxing muscles and tendons to promote blood circulation, coronary circulation-promoting pain-relieving, the function of reinforcing the kidney to strengthen the bone.Herba Lycopodii expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral in side, to eliminate external heresy; Herba Saussureae Involueratae invigorating the liver and kidney, bone and muscle strengthening, kidney-replenishing adjust punching to appoint, and make healthy energy internal memory, and activating YANG and prormoting functioning of QI, promotes impaired joint tissue tissue regeneration promoting; Radix Dipsaci, Fructus Chaenomelis, the removing dampness of Radix Flemingiae Philippinensis stomach function regulating, blood circulation regulating, for promoting impaired joint blood circulation, the nutrition of supply joint, recovers impaired function of joint; Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae heat-clearing and toxic substances removing, promoting the circulation of QI to relieve pain, eliminate local inflammation; Nidus Vespae, Cortex Acanthopancis, Folium Artemisiae Argyi warming the meridian for stopping bleeding, antiallergic, suppresses humoral immunization.All medicine compatibilities, bring out the best in each other, and play altogether expelling wind and removing dampness, dispersing cold for relieving pain, blood circulation promoting and blood stasis dispelling, relaxing muscles and tendons and activating QI and blood in the collateral, effect of benefiting QI and nourishing blood.
The present invention adopts the Chinese crude drug of different properties, has carried out science compatibility, easy to use, safe and reliable, has no side effect, and reaches the object for the treatment of both the principal and secondary aspects of a disease, and rheumatic arthritis is had to good therapeutic effect.
The specific embodiment
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
Raw material composition and the weight of effective ingredient of the present invention are:
Herba Lycopodii 15g Herba Saussureae Involueratae 15g Radix Dipsaci 23g Fructus Chaenomelis 16g
Radix Flemingiae Philippinensis 23g Rhizoma Chuanxiong 16g Rhizoma Paridis 25g Scorpio 25g
Rhizoma Curcumae 15g Nidus Vespae 16g Cortex Acanthopancis 25g Folium Artemisiae Argyi 14g.
The processing step of process for preparing medicine of the present invention is:
(1) by each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process after mix homogeneously, porphyrize, crosses 120 order fine powders, for subsequent use.
(2) add in container after remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis are mixed homogeneously with Radix Flemingiae Philippinensis, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, Folium Artemisiae Argyi, add the water of 8 times of amounts, extract 2 hours, filter taking liquid; In remaining residue, add again the water of 6 times of amounts, extract 1 hour, filter taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of relative density 1.10~1.15 at 60 ℃, drying under reduced pressure.
(3) add step (2) to make mix homogeneously in thick paste gained fine powder in step (1), in 50~60 ℃ dry after, be ground into 120 object medicated powder, obtain the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant, be prepared into capsule according to routine techniques.
Usage and dosage: every day 3 times, each 3~6g, warm water delivery service in half an hour, 10 days is a course for the treatment of after meal, and common 1~2 course for the treatment of is effective, and pertinacious disease needs 3~4 courses for the treatment of.
Embodiment 2
Raw material composition and the weight of effective ingredient of the present invention are:
Herba Lycopodii 12g Herba Saussureae Involueratae 12g Radix Dipsaci 15g Fructus Chaenomelis 10g
Radix Flemingiae Philippinensis 15g Rhizoma Chuanxiong 10g Rhizoma Paridis 18g Scorpio 18g
Rhizoma Curcumae 12g Nidus Vespae 10g Cortex Acanthopancis 18g Folium Artemisiae Argyi 10g.
The processing step of process for preparing medicine of the present invention is:
(1) by each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process after mix homogeneously, porphyrize, crosses 120 order fine powders, for subsequent use.
(2) add in container after remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis are mixed homogeneously with Radix Flemingiae Philippinensis, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, Folium Artemisiae Argyi, add the water of 8 times of amounts, extract 2.5 hours, filter taking liquid; In remaining residue, add again the water of 6 times of amounts, extract 1.5 hours, filter taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of relative density 1.10~1.15 at 60 ℃, drying under reduced pressure.
(3) add step (2) to make mix homogeneously in thick paste gained fine powder in step (1), in 50~60 ℃ dry after, be ground into 120 object medicated powder, obtain the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant, be prepared into granule according to routine techniques.
Usage and dosage: every day 3 times, each 3~6g, warm water delivery service in half an hour, 10 days is a course for the treatment of after meal, and common 1~2 course for the treatment of is effective, and pertinacious disease needs 3~4 courses for the treatment of.
Embodiment 3
Raw material composition and the parts by weight of effective ingredient of the present invention are:
Herba Lycopodii 18g Herba Saussureae Involueratae 18g Radix Dipsaci 30g Fructus Chaenomelis 20g
Radix Flemingiae Philippinensis 30g Rhizoma Chuanxiong 20g Rhizoma Paridis 35g Scorpio 35g
Rhizoma Curcumae 18g Nidus Vespae 20g Cortex Acanthopancis 35g Folium Artemisiae Argyi 16g.
The processing step of process for preparing medicine of the present invention is:
(1) by each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process after mix homogeneously, porphyrize, crosses 120 order fine powders, for subsequent use.
(2) add in container after remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis are mixed homogeneously with Radix Flemingiae Philippinensis, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, Folium Artemisiae Argyi, add the water of 8 times of amounts, extract 3 hours, filter taking liquid; In remaining residue, add again the water of 6 times of amounts, extract 2 hours, filter taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of relative density 1.10~1.15 at 60 ℃, drying under reduced pressure.
(3) add step (2) to make mix homogeneously in thick paste gained fine powder in step (1), in 50~60 ℃ dry after, be ground into 120 object medicated powder, obtain the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant, be prepared into tablet according to routine techniques.
Usage and dosage: every day 3 times, each 3~6g, warm water delivery service in half an hour, 10 days is a course for the treatment of after meal, and common 1~2 course for the treatment of is effective, and pertinacious disease needs 3~4 courses for the treatment of.
Clinical data:
1, case selection
The routine clinical observation of rheumatic arthritis patient 400 of selecting my institute or outer court to make a definite diagnosis, patient is divided into two groups at random, treatment group 200 examples, wherein male's 102 examples, women's 98 examples, 18~64 years old age, 46.8 years old mean age, the shortest person of the course of disease 6 months, elder 28 years, average 8.2 years.Matched group 200 examples, wherein male's 105 examples, women's 95 examples, 17~62 years old age, 44.2 years old mean age, the course of disease 8 months~23 years, average 7.9 years.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, treatment group patient takes medicine of the present invention, adult every day 3 times, and each 3~6g, warm water delivery service in half an hour, 10 days is a course for the treatment of after meal, and common 1~2 course for the treatment of is effective, and pertinacious disease needs 3~4 courses for the treatment of.Matched group is taken phenylbutazone tablet, each 0.1~0.2g, every day 3 times, oral meal.
3, efficacy determination:
(1) effective: body constitution strengthens, with it energetically; Red, swollen, hot, the pain of joint and soft tissue are obviously alleviated; Morning, deadlock alleviated; Joint deformity is alleviated.
(2) effective: body constitution strengthens, with it energetically; Red, swollen, hot, the pain in joint are alleviated to some extent.
(3) invalid: disease is unchanged.
4, result
Take in the treatment group of medicine of the present invention effective 145 examples, effective 43 examples, invalid 12 examples, total effective rate 94%.
Effective 43 examples in matched group, effective 90 examples, invalid 67 examples, total effective rate 66.5%.
Above result demonstration, treatment group total effective rate is apparently higher than matched group.
Model case is given an example:
1, Lee × ×, female, 48 years old, secondary school teachers.Whole body arthralgia is shown effect 6 years repeatedly, and limbs are heavy, and rise stiff morning, and joint joint stuffiness is met cold rnning weight.Clinical diagnosis: rheumatic arthritis, card belongs to cold warm numbness disease.Take medicine of the present invention after 30 days, play stiff all diseases in arthralgia, morning and disappear, functional rehabilitation, chemical examination takes stopgap measures all normal.Follow up a case by regular visits to not recurrence so far.
2, in vain × ×, man, 36 years old, Enterprise Staff.Before 5 years, had a cold, be afraid of cold at that time, arthritis, uses Western medicine pain relieving, cures the symptoms, not the disease, whenever cloudy day, rainy, cold day two fingers, toe, double knee joint pain, within nearly 1 year, disease increases the weight of, forefinger, the existing distortion of middle articulations digitorum manus, and upper arm can not be gone up act, back and whole body arthralgia, overcast and rainy enter hurt like hell especially after the winter.The performance of this patient clinical meets rheumatic arthritis symptom, and the cause of disease is due to the overworked weakness of health, and sick imbalance for a long time, took medicine of the present invention after 40 days again, and the aversion to wind arthralgia of being afraid of cold transference cure, follows up a case by regular visits to, without recurrence.
3, recklessly × ×, female, 42 years old, civil servant.Arthralgia for many years, is diagnosed as rheumatic arthritis in hospital, rear long-term steroid, analgesic, and attempted various naturopathy methods, and effect is all not obvious, and increase in the joint of getting involved, handicapped.Taking medicine of the present invention after 20 days, symptom takes a turn for the better, continue to take after 10 days, and transference cure, activity freely, is not recurred.
4, congratulate × ×, man, 29 years old, builder.Start to occur lumbago without obvious inducement the year before, more very, after several days, lumbago is alleviated in activity, pain and double knee joint, after be gradually developed to duplex joint, carpal joint and two ankle joint, be migration, pain joint motion is unfavorable, is diagnosed as rheumatic arthritis.Take medicine of the present invention after one month, symptom disappears completely, and pain disappears, and livelihood restoration is normal.

Claims (4)

1. a medicine for the treatment of rheumatic arthritis, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
10~20 parts of 15~30 portions of Fructus Chaenomeliss of 12~18 parts of Radix Dipsacis of 12~18 parts of Herba Saussureae Involuerataes of Herba Lycopodii
18~35 parts of 18~35 portions of Scorpios of 10~20 parts of Rhizoma Paridis of 15~30 parts of Rhizoma Chuanxiongs of Radix Flemingiae Philippinensis
10~16 parts of 18~35 portions of Folium Artemisiae Argyis of 10~20 parts of Cortex Acanthopanciss of 12~18 parts of Nidus Vespae of Rhizoma Curcumae.
2. a kind of medicine for the treatment of rheumatic arthritis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
13~18 parts of 20~25 portions of Fructus Chaenomeliss of 14~17 parts of Radix Dipsacis of 14~17 parts of Herba Saussureae Involuerataes of Herba Lycopodii
22~28 parts of 22~28 portions of Scorpios of 13~18 parts of Rhizoma Paridis of 20~25 parts of Rhizoma Chuanxiongs of Radix Flemingiae Philippinensis
12~15 parts of 22~28 portions of Folium Artemisiae Argyis of 13~18 parts of Cortex Acanthopanciss of 14~17 parts of Nidus Vespae of Rhizoma Curcumae.
3. a kind of medicine for the treatment of rheumatic arthritis according to claim 1, is characterized in that: raw material composition and the parts by weight of making described effective ingredient are:
16 parts of 23 portions of Fructus Chaenomeliss of 15 parts of Radix Dipsacis of 15 parts of Herba Saussureae Involuerataes of Herba Lycopodii
25 parts of 25 portions of Scorpios of 16 parts of Rhizoma Paridis of 23 parts of Rhizoma Chuanxiongs of Radix Flemingiae Philippinensis
14 parts of 25 portions of Folium Artemisiae Argyis of 16 parts of Cortex Acanthopanciss of 15 parts of Nidus Vespae of Rhizoma Curcumae.
4. a preparation method for the treatment of the medicine of rheumatic arthritis, is characterized in that: comprise following processing step:
(1) by each 50% mixing of Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis weight, carry out pulverization process after mix homogeneously, porphyrize, crosses 120 order fine powders, for subsequent use.
(2) add in container after remaining Herba Lycopodii, Herba Saussureae Involueratae, Radix Dipsaci, Fructus Chaenomelis are mixed homogeneously with Radix Flemingiae Philippinensis, Rhizoma Chuanxiong, Rhizoma Paridis, Scorpio, Rhizoma Curcumae, Nidus Vespae, Cortex Acanthopancis, Folium Artemisiae Argyi, add the water of 8 times of amounts, extract 2~3 hours, filter taking liquid; In remaining residue, add again the water of 6 times of amounts, extract 1~2 hour, filter taking liquid; Merge medicinal liquid twice, be condensed into the thick paste of relative density 1.10~1.15 at 60 ℃, drying under reduced pressure.
(3) add step (2) to make mix homogeneously in thick paste gained fine powder in step (1), in 50~60 ℃ dry after, be ground into 120 object medicated powder, obtain the active ingredient raw materials medicine of product of the present invention, in this crude drug, add pharmaceutic adjuvant to be prepared into various pharmaceutical formulations.
CN201210394974.3A 2012-10-10 2012-10-10 Medicine for treating rheumatic arthritis and preparation method thereof Expired - Fee Related CN102872420B (en)

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