CN104435524A - External application powder for treating cervical spondylotic myelopathy and preparation method of external application powder - Google Patents
External application powder for treating cervical spondylotic myelopathy and preparation method of external application powder Download PDFInfo
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Abstract
The invention discloses external application powder for treating cervical spondylotic myelopathy. The external application powder comprises the following crude drugs in parts by weight: 9-30 parts of russula nigricans, 6-12 parts of fructus leonuri, 5-9 parts of drynaria rhizome, 10-15 parts of rhizoma dioscoreae nipponicae, 1-5 parts of pseudo-ginseng, 9-15 parts of lycopodium clavatum, 4-9 parts of salviae miltiorrhizae, 3-12 parts of akebiaquinata, 10-25 parts of cassia twig, 4-10 parts of ophidia, 3-9 parts of rhizoma corydalis and 3-9 parts of medicinal cyathula root. The external application powder has a significant effect on cervical spondylotic myelopathy, and is capable of relieving pain, relaxing the muscles and stimulating the blood circulation, recuperating gas and blood, and improving fragile health of a patient caused by long-term pain; and most of crude drugs adopt local common medicinal materials, so that the external application powder is low in price; and the economic burden of the patient is relieved.
Description
Technical field
The invention belongs to traditional Chinese medicine field, especially a kind of Dressed medicine powder for the treatment of cervical spondylotic myelopathy and preparation method thereof.
Background technology
Cervical spondylosis, also known as cervical spine syndrome, is the general name of osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion, is a kind of illness changing into basis with degeneration pathology.Strain for a long time mainly due to cervical vertebra, hyperosteogeny, or prolapse of intervertebral disc, ligament thicken, and cause cervical vertebra spinal cord, nerve root or vertebral artery pressurized, occur a series of handicapped clinical syndrome.Show as intervertebral disc degradation itself and insecondary a series of pathological change thereof, as vertebra joint unstability, loosen; Nucleus pulposus or deviate from; Bony spur is formed; The spinal canal stenosis etc. of ligament plumpness and secondary, stimulates or has oppressed the tissues such as the nerve root of vicinity, spinal cord, vertebral artery and cervical region sympathetic nerve, cause series of symptoms and sign.
Cervical spondylotic myelopathy is because cervical vertebral body degeneration and adjacent soft tissue are (as intervertebral disk hernia, vertebral body trailing edge bony spur, ossification of posterior longitudinal ligament, hypertrophy of ligamentum flavum or calcification, spinal canal stenosis etc.) regression cause direct compressing to spinal cord, add the impact of the dynamic factor such as violent motion or long-term faulty posture, cause compression of spinal cord or ischemia of spinal cord, then there is the dysfunction of spinal cord, clinical manifestation is as unable in numb limbs and tense tendons, movable ineffective, the sensation etc. stepping on Cotton Gossypii is had when walking, though this myelopathy is comparatively rare, but serious symptom, and develop mainly with the form of recessiveness invasion and attack, easy mistaken diagnosis is for other illness and delay treatment opportunity, therefore it is in critical role in all myelopathys.
The clinical symptoms of cervical spondylosis is comparatively complicated.Mainly contain nape pain, upper myasthenia of limbs, point numb, lower limb are weak, difficulty in walking, dizziness, Nausea and vomiting, even blurred vision, tachycardia and dysphagia etc.Clinical symptoms and the diseased region of cervical spondylosis, involved and individual variation is organized to have certain relation.
In the invention of existing treatment cervical spondylotic myelopathy, the Chinese patent of application publication number CN 103230447 A (application number 201310115163.X) discloses a kind of external medicine wine for the treatment of cervical spondylosis, and formula and part by weight are Semen Strychni 10 parts, Radix Puerariae 20 parts, Radix Aconiti 12 parts, Radix Aconiti Kusnezoffii 10 parts, Radix Clematidis 20 parts, Hirudo 15 parts, Zaocys 15 parts, Caulis Spatholobi 25 parts, Borneolum Syntheticum 6 parts; Above-mentioned raw materials medicine is weighed in proportion and assorts, with pharmaceutical equipment apparatus concoct qualified, purify, concentrated make fine powder after to adjust in 1: 100 ratio with 75% ethanol or 600 Chinese liquor that to convert into medicated wine for subsequent use, it is very fast to smear rear volatilization, cannot continuingly act on affected part.The Chinese patent of Authorization Notice No. CN 102406789 B (application number 201110393441.9) discloses a kind of plaster for the treatment of cervical spondylosis: Radix Angelicae Sinensis 30 grams, Radix Salviae Miltiorrhizae 40 grams, Herba Aristolochiae Mollissimae 35 grams, Formica fusca 35 grams, Semen Sinapis Albae 40 grams, Radix Achyranthis Bidentatae 30 grams, Fructus Foeniculi 35 grams, Radix Aconiti Kusnezoffii 20 grams, Rhizoma Chuanxiong 30 grams, Scolopendra 20 grams, Scorpio 30 grams, Semen Strychni 30 grams, Rhizoma Dioscoreae Nipponicae 30 grams, Myrrha 40 grams, Olibanum 30 grams, Borneolum Syntheticum 30 grams, preparation method: get Radix Angelicae Sinensis 30 grams, Radix Salviae Miltiorrhizae 40 grams, Herba Aristolochiae Mollissimae 35 grams, Formica fusca 35 grams, Semen Sinapis Albae 40 grams, Radix Achyranthis Bidentatae 30 grams, Fructus Foeniculi 35 grams, Radix Aconiti Kusnezoffii 20 grams, Rhizoma Chuanxiong 30 grams, Scolopendra 20 grams, Scorpio 30 grams, Semen Strychni 30 grams, add 5 times to the water of said medicine weight, slow fire boiling is dragged for slag after 60 minutes and is made decoction, Rhizoma Dioscoreae Nipponicae 30 grams is added in decoction, Myrrha 40 grams, Olibanum 30 grams, Borneolum Syntheticum 30 grams, slow fire be heated to agent dissolving after, add Plumbum preparatium again and make ointment, cream of getting it filled evenly is applied on the cloth of stand and makes plaster, every 10 gram of one subsides, if life-time service easily produces drug resistance.
Summary of the invention
For the present situation of existing treatment cervical spondylotic myelopathy deficiency, an object of the present invention is the external pulvis providing treatment cervical spondylotic myelopathy, has easy absorption, the feature that pain relieving is fast, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Another object of the present invention is just to provide the preparation method of above-mentioned external pulvis.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The external pulvis for the treatment of cervical spondylotic myelopathy, each crude drug is as follows, is weight portion: dark red mushroom 9-30, Fructus Leonuri 6-12, Rhizoma Drynariae 5-9, Rhizoma Dioscoreae Nipponicae 10-15, Radix Notoginseng 1-5, Herba Lycopodii 9-15, Radix Salviae Miltiorrhizae 4-9, Caulis Akebiae 3-12, Ramulus Cinnamomi 10-25, ophidia 4-10, Rhizoma Corydalis 3-9, Radix Cyathulae 3-9.
The external pulvis for the treatment of cervical spondylotic myelopathy, preferred scheme is, each crude drug is as follows, be weight portion: dark red mushroom 15-25, Fructus Leonuri 7-10, Rhizoma Drynariae 6-8, Rhizoma Dioscoreae Nipponicae 12-14, Radix Notoginseng 2-4, Herba Lycopodii 10-13, Radix Salviae Miltiorrhizae 5-7, Caulis Akebiae 5-10, Ramulus Cinnamomi 15-20, ophidia 6-9, Rhizoma Corydalis 5-8, Radix Cyathulae 5-7.
The external pulvis for the treatment of cervical spondylotic myelopathy, better preferred scheme is that each crude drug is as follows, is weight portion: dark red mushroom 20, Fructus Leonuri 8, Rhizoma Drynariae 7, Rhizoma Dioscoreae Nipponicae 13, Radix Notoginseng 3, Herba Lycopodii 11, Radix Salviae Miltiorrhizae 6, Caulis Akebiae 7, Ramulus Cinnamomi 18 parts, ophidia 8, Rhizoma Corydalis 6, Radix Cyathulae 6.
The preparation method of above-mentioned external pulvis, preparation process is as follows:
(1) decaptitated by ophidia, the block being cut into 0.5-1.5cm (preferred 1cm) puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, soak 1-3 days, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 1-5 minute fast, takes out, sieve shakeout, spreading for cooling;
(2) by dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Rhizoma Dioscoreae Nipponicae white vinegar soak 10-20 hour (preferably 15 hours), taking-up is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Herba Lycopodii, Radix Salviae Miltiorrhizae, Caulis Akebiae, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Cyathulae add in step (1) gained filtrate, and mixing, after slightly vexed 1-5 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10-30 minute at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30-50 minute slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 1-3 slowly, namely cool bottling of drying in the air obtains external pulvis.
The preparation method of foregoing external pulvis, the consumption of step (1) jowar wine is that the 2-6 of the total consumption of ophidia and Radix Salviae Miltiorrhizae is doubly (preferred, the consumption of jowar wine is 3-5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, more preferably good, the consumption of jowar wine is 4 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae).
The preparation method of foregoing external pulvis, step (1) drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, and stir-fry 2-4 minute fast, (preferably drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes).
The preparation method of foregoing external pulvis, the consumption of step (2) white vinegar is dark red mushroom, Fructus Leonuri, doubly (preferred, the consumption of white vinegar is dark red mushroom to the 1-5 of Rhizoma Drynariae and Yam total weight, Fructus Leonuri, doubly, be more added with choosing, the consumption of white vinegar is dark red mushroom for the 2-4 of Rhizoma Drynariae and Yam total weight, Fructus Leonuri, Rhizoma Drynariae and Yam total weight 3 times).
The preparation method of foregoing external pulvis, step (3), after slightly vexed 2-4 hour, decocts with water 2 times, intense fire is fried open for the first time, turns and (preferably after slightly vexed 3 hours, decocts with water 2 times in 15-25 at a simmer minute, intense fire is fried open for the first time, turns 20 minutes at a simmer).
The preparation method of foregoing external pulvis, step (3) low baking temperature that again adds water is decocted 35-45 minute (preferred, the low baking temperature that again adds water decocts 40 minutes slowly) slowly.
The preparation method of foregoing external pulvis, step (4) is placed in low baking temperature on clean tile when drying 1.5-2.5 slowly when on clean tile, low baking temperature dries 2 slowly (preferred, be placed in).
Using method: for making the present invention reach optimum therapeuticing effect, during use, gets Chinese powder medicine 40-60g of the present invention, with Ovum Gallus domesticus album mixing, is applied on adhesive plaster, sticks in lumbar vertebra place, within 1 day, changes once, within 5 days, is a course for the treatment of.
This external pulvis, can not only pain relieving to the Be very effective of cervical spondylotic myelopathy, can also relaxing muscles and tendons to promote blood circulation, and QI and blood regulating, improves the body constitution of patient's weakness because of chronic pain, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The external pulvis for the treatment of cervical spondylotic myelopathy, the pharmacological effect of each crude drug is respectively:
Dark red mushroom: base is former: be the sporophore of the dark red mushroom of Russulaceae Russula fungus.Composition: sporophore contains ergosterol, 5,7-Ergota steroid diene-3 β-ol.The property of medicine: " national Chinese herbal medicine compilation ": " micro-salty, temperature." function cures mainly: functions dispelling wind and clearing away cold, removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly anemofrigid-damp arthralgia, lumbago and skelalgia, arthralgia, numb hand and foot, tic of the limbs.
Fructus Leonuri: be the fruit of Labiatae mother wort plant Herba Leonuri and Herba Leonuri Sibirici.Composition: leonuri,fructus contains allene class fatty acid containing alkaloid, herb containing phenolic glycoside class, Herba Leonuri Sibirici fruit kind oil.Pharmacology: have hypotensive effect, has the effect of stimulon palace excitement.The property of medicine: sweet, pungent, be slightly cold, mild toxicity, return Liver Channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, liver heat removing and eyesight improving.
Rhizoma Drynariae: nature and flavor: bitter, temperature.Gui Jing: return kidney, Liver Channel.Effect: the kidney invigorating bone strengthening, continues and hinders pain relieving.Cure mainly: for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.
Rhizoma Dioscoreae Nipponicae: another name Dioscorea nipponica Mak. Ningpo Yam Rhizome, Rhizoma Dioscoreae Nipponicae, Dioscorea nipponica bone, ground joist, Rhizoma Smilacis Bockii, chicken bone, mountain Radix Dichroae, Radix Dichroae, parthenocissus, tip of a whip dish.Flavor efficacy: bitter is flat.Return liver, lung meridian.Function relaxing muscles and tendons to promote blood circulation, timid wind pain relieving, relieving cough and asthma, timid expectorant.Be applicable to lumbago and skelalgia, muscles and bones numbness, traumatic injury, lumbar sprain and QI divergeny, cough pant.
Radix Notoginseng: nature and flavor: sweet, micro-hardship, temperature.Gui Jing: return liver, stomach warp.Effect: dissipating blood stasis stops blooding, subduing swelling and relieving pain.Cure mainly: for spitting of blood, spit blood, epistaxis, has blood in stool, metrorrhagia, traumatic hemorrhage, breast ventral spine pain, tumbling and swelling.
Herba Lycopodii: nature and flavor: micro-hardship, pungent, temperature.Gui Jing: return liver,spleen,kidney warp.Effect: expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly: for joint aches, joint stuffiness.
Radix Salviae Miltiorrhizae: nature and flavor: bitter, is slightly cold.Gui Jing: GUIXIN, Liver Channel.Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness.Cure mainly: for menoxenia, amenorrhea dysmenorrhea ， WEIJIA is gathered, breast ventral spine pain, pyretic arthralgia pain, and skin infection swells and ache, dysphoria and insomnia; Hepatosplenomegaly, angina pectoris.
Caulis Akebiae: nature and flavor: bitter, is slightly cold.Gui Jing: GUIXIN, small intestinal, urinary bladder channel.Effect: clearing away heart-fire, diuresis, stimulating milk secretion of stimulating the menstrual flow.Cure mainly: for irritable feverish sensation in the chest, larynx disease pharyngalgia, dark coloured urine, five types of stranguria, edema, whole body spasm and pain, amenorrhea breast is few.
Ramulus Cinnamomi: nature and flavor: acrid, sweet, warm.Gui Jing: GUIXIN, lung, urinary bladder channel.Effect: diaphoresis expelling pathogenic factors from muscles, promoting the flow of QI-blood by warming the meridian, supporing yang activating QI, the flat gas that spins.Cure mainly: for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.
Ophidia: Zaocys, is commonly called as Zaocys, zaocys dhumnades, for Colubridae Zaocys belongs to the larger nonpoisonous snake of the bodily form, sweet, flat.Return Liver Channel.Dispel the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Rhizoma Corydalis: nature and flavor: pungent, bitter, temperature.Gui Jing: return liver, spleen channel.Effect: invigorate blood circulation, promoting the circulation of QI, pain relieving.Cure mainly: for the breast side of body, epigastric pain. amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Radix Cyathulae: nature and flavor: sweet, micro-hardship, flat.Gui Jing: return liver, kidney channel.Effect: eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome.Cure mainly: for amenorrhea carcinoma, retention of placenta, arthralgia, sufficient health clonic spasm of the muscle, hematuria stranguria with blood, injury from falling down.
External pulvis of the present invention is based on the principle of traditional Chinese medical herbal treatment cervical spondylotic myelopathy.The Chinese medicinal material selected all has relaxing muscles and tendons to promote blood circulation, effect of pain relieving, and cheap, and life-time service also can not cause the financial burden of patient, is to treat the ideal medicine of cervical spondylotic myelopathy.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 treats the external pulvis of cervical spondylotic myelopathy, and each crude drug is as follows, is weight portion (getting 10g for every part): 9 parts, dark red mushroom, Fructus Leonuri 6 parts, Rhizoma Drynariae 5 parts, Rhizoma Dioscoreae Nipponicae 10 parts, Radix Notoginseng 1 part, Herba Lycopodii 9 parts, Radix Salviae Miltiorrhizae 4 parts, Caulis Akebiae 3 parts, Ramulus Cinnamomi 10 parts, ophidia 4 parts, Rhizoma Corydalis 3 parts, Radix Cyathulae 3 parts.
The preparation method of the external pulvis of above-mentioned treatment cervical spondylotic myelopathy, step is:
(1) decaptitated by ophidia, the block being cut into 0.5cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into Sorghum vulgare Pers. Wine, the consumption of jowar wine is 2 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 1 day, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 1 minute, take out, sieve shakeout, spreading for cooling;
(2) by dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Rhizoma Dioscoreae Nipponicae white vinegar soak 10 hours, the consumption of white vinegar is dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Yam total weight 1 times, takes out and is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Herba Lycopodii, Radix Salviae Miltiorrhizae, Caulis Akebiae, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Cyathulae add in step (1) gained filtrate, and mixing, after slightly vexed 1 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined in step (3) gained filtrate by step (2) gained smalls, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 1 slowly, namely cool bottling of drying in the air obtains external pulvis.
Model case one Zou XX, man, 40 years old, Harbin, Heilungkiang personage, peasant, Mr. Zou both sides numbness of lower limbs, pain, stiffly shake and do not have unable on foot, thinking it is that work is tired out at the beginning, also do not take notice of very much, but occur that both upper extremities is numb in the time of nearest half a year, use chopsticks to have one's meal hand shaking, and grasp weakness easily loses article.Patient's fearing very at that time, checks to Harbin City's large hospital under the accompanying of layman, checks and finds patient's restriction of neck motion, and the pain increased in layback, and cervical region tenderness is obvious, is diagnosed as: cervical spondylotic myelopathy.
Use embodiment 1 gained external pulvis, use 10 days healths pain relief everywhere, feel there is strength; Use 20 days, the pain of cervical region disappears, and can normally walk; Continue use 1 month malaise symptoms to disappear completely; After use again external pulvis plaster of the present invention to consolidate 1 month, drug withdrawal so far without recurrence.
Embodiment 2 treats the external pulvis of cervical spondylotic myelopathy, and each crude drug is as follows, is weight portion (getting 15g for every part): 30 parts, dark red mushroom, Fructus Leonuri 12 parts, Rhizoma Drynariae 9 parts, Rhizoma Dioscoreae Nipponicae 15 parts, Radix Notoginseng 5 parts, Herba Lycopodii 15 parts, Radix Salviae Miltiorrhizae 9 parts, Caulis Akebiae 12 parts, Ramulus Cinnamomi 25 parts, ophidia 10 parts, Rhizoma Corydalis 9 parts, Radix Cyathulae 9 parts.
The preparation method of the external pulvis of above-mentioned treatment cervical spondylotic myelopathy, step is:
(1) decaptitated by ophidia, the block being cut into 1.5cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 6 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 3 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 5 minutes, take out, sieve shakeout, spreading for cooling;
(2) by dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Rhizoma Dioscoreae Nipponicae white vinegar soak 20 hours, the consumption of white vinegar is dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Yam total weight 5 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Herba Lycopodii, Radix Salviae Miltiorrhizae, Caulis Akebiae, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Cyathulae add in step (1) gained filtrate, and mixing, after slightly vexed 5 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 30 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 50 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined in step (3) gained filtrate by step (2) gained smalls, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 3 slowly, namely cool bottling of drying in the air obtains external pulvis.
Embodiment 3 treats the external pulvis of cervical spondylotic myelopathy, and each crude drug is as follows, is weight portion (getting 20g for every part): 15 parts, dark red mushroom, Fructus Leonuri 7 parts, Rhizoma Drynariae 6 parts, Rhizoma Dioscoreae Nipponicae 12 parts, Radix Notoginseng 2 parts, Herba Lycopodii 10 parts, Radix Salviae Miltiorrhizae 5 parts, Caulis Akebiae 5 parts, Ramulus Cinnamomi 15 parts, ophidia 6 parts, Rhizoma Corydalis 5 parts, Radix Cyathulae 5 parts.
The preparation method of the external pulvis of above-mentioned treatment cervical spondylotic myelopathy, step is:
(1) decaptitated by ophidia, the block being cut into 0.8cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 3 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 1.5 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 2 minutes, take out, sieve shakeout, spreading for cooling;
(2) by dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Rhizoma Dioscoreae Nipponicae white vinegar soak 13 hours, the consumption of white vinegar is dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Yam total weight 2 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Herba Lycopodii, Radix Salviae Miltiorrhizae, Caulis Akebiae, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Cyathulae add in step (1) gained filtrate, and mixing, after slightly vexed 2 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 13 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 35 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined in step (3) gained filtrate by step (2) gained smalls, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 1.5 slowly, namely cool bottling of drying in the air obtains external pulvis.
Model case two Liu XX, man, 60 years old, Jinan, Shandong Province city, retired aged teacher.What serve as a teacher in study takes over a class for an absent teacher often, often bow and correct students' papers, cause there is slight cervical spondylosis, except strength vertebra pain increases the weight of after retirement, have also appeared symptom uncomfortable in chest, and with the symptom of blurred vision, nearest two-arm sensation grips unable, health has constrained sense, couches night and all feels uncomfortable, cannot fall asleep and cause lethargy.Check and find patient's instability of gait, hands grasping power is all not high, and right arm situation is even more serious, compression of spinal cord is comparatively obvious, is originally diagnosed as myeloid form strength vertebra sick, seeks medical advice everywhere, all to no effect, son sees unintentionally external pulvis of the present invention on TV, has just bought 4 courses for the treatment of to patient.
Use embodiment 3 gained external pulvis, use 5 days, pain, symptom uncomfortable in chest are alleviated to some extent; Use 20 days, malaise symptoms disappears substantially; Use again 1 first quarter moon as consolidation, after drug withdrawal, do not have any discomfort symptom, and appearance without any side effects during using embodiment 3 gained external pulvis.
Embodiment 4 treats the external pulvis of cervical spondylotic myelopathy, and each crude drug is as follows, is weight portion (getting 25g for every part): 25 parts, dark red mushroom, Fructus Leonuri 10 parts, Rhizoma Drynariae 8 parts, Rhizoma Dioscoreae Nipponicae 14 parts, Radix Notoginseng 4 parts, Herba Lycopodii 13 parts, Radix Salviae Miltiorrhizae 7 parts, Caulis Akebiae 10 parts, Ramulus Cinnamomi 20 parts, ophidia 9 parts, Rhizoma Corydalis 8 parts, Radix Cyathulae 7 parts.
The preparation method of the external pulvis of above-mentioned treatment cervical spondylotic myelopathy, step is:
(1) decaptitated by ophidia, the block being cut into 1.3cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is 5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, soaks 2.5 days, filters, filtrate is for subsequent use, getting sand puts in hot pot, fries to sliding sharp state, drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 4 minutes, take out, sieve shakeout, spreading for cooling;
(2) by dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Rhizoma Dioscoreae Nipponicae white vinegar soak 18 hours, the consumption of white vinegar is dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Yam total weight 4 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Herba Lycopodii, Radix Salviae Miltiorrhizae, Caulis Akebiae, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Cyathulae add in step (1) gained filtrate, and mixing, after slightly vexed 4 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 25 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 45 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined in step (3) gained filtrate by step (2) gained smalls, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 2.5 slowly, namely cool bottling of drying in the air obtains external pulvis.
Embodiment 5 treats the external pulvis of cervical spondylotic myelopathy, and each crude drug is as follows, is weight portion (getting 30g for every part): 20 parts, dark red mushroom, Fructus Leonuri 8 parts, Rhizoma Drynariae 7 parts, Rhizoma Dioscoreae Nipponicae 13 parts, Radix Notoginseng 3 parts, Herba Lycopodii 11 parts, Radix Salviae Miltiorrhizae 6 parts, Caulis Akebiae 7 parts, Ramulus Cinnamomi 18 parts, ophidia 8 parts, Rhizoma Corydalis 6 parts, Radix Cyathulae 6 parts.
The preparation method of the external pulvis of above-mentioned treatment cervical spondylotic myelopathy, step is:
(1) decaptitated by ophidia, the block being cut into 1cm puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, the consumption of jowar wine is ophidia and pellet, 4 times that join total consumption, soaks 2 days, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes, take out, sieve shakeout, spreading for cooling;
(2) by dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Rhizoma Dioscoreae Nipponicae white vinegar soak 15 hours, the consumption of white vinegar is dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Yam total weight 3 times, take out and are placed in low baking temperature on tile and are dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Herba Lycopodii, Radix Salviae Miltiorrhizae, Caulis Akebiae, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Cyathulae add in step (1) gained filtrate, and mixing, after slightly vexed 3 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 20 minutes at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 40 minutes slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined in step (3) gained filtrate by step (2) gained smalls, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 2 slowly, namely cool bottling of drying in the air obtains external pulvis.
1, experimental example: the clinical practice of the external pulvis of embodiment 5 gained treatment cervical spondylotic myelopathy: screen 300 routine patients in 4 hospitals, oldest 60 years old, minimal ages 30 years old, 45 years old mean age.Before test 1 week, Continuous Observation is carried out to this crowd, record symptom and change, be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 gained external pulvis, and matched group uses other medicine (medicine of the conventional therapy cervical spondylotic myelopathy such as Radix Salviae Miltiorrhizae Tabellae, compound recipe chrondroitin sheet).Using method is: using method: for making the present invention reach optimum therapeuticing effect, during use, gets Chinese powder medicine 40-60g of the present invention, with Ovum Gallus domesticus album mixing, is applied on adhesive plaster, sticks in strength vertebra place, within 1 day, changes once, within 10 days, is a course for the treatment of.Curative effect situation criterion: cure: malaise symptoms all disappears, effectively: after using this product, malaise symptoms alleviates or partial disappearance; Invalid: after using this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1:
Prove through clinical trial, external pulvis of the present invention is on treatment cervical spondylotic myelopathy, and effective percentage is 99%, and cure rate is 95%, and exceed 9% than the medicine effective percentage of externally-used pain-relieving, cure rate exceeds 70%, and thoroughly can remove old complaint, makes the recovery from illness that patient is real; The Chinese medicine effective percentage of class treatment cervical spondylotic myelopathy more oral than other exceeds 14%, and cure rate is high by 25%, and can not cause any burden to the health of patient.External pulvis instant effect of the present invention, can reach the object alleviating rapidly patient's misery, and relapse rate is low, is a kind of external pulvis for the treatment of cervical spondylotic myelopathy safely and effectively.
Claims (10)
1. treat the external pulvis of cervical spondylotic myelopathy, it is characterized in that: each crude drug is as follows, is weight portion: dark red mushroom 9-30, Fructus Leonuri 6-12, Rhizoma Drynariae 5-9, Rhizoma Dioscoreae Nipponicae 10-15, Radix Notoginseng 1-5, Herba Lycopodii 9-15, Radix Salviae Miltiorrhizae 4-9, Caulis Akebiae 3-12, Ramulus Cinnamomi 10-25, ophidia 4-10, Rhizoma Corydalis 3-9, Radix Cyathulae 3-9.
2. the external pulvis for the treatment of cervical spondylotic myelopathy according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: dark red mushroom 15-25, Fructus Leonuri 7-10, Rhizoma Drynariae 6-8, Rhizoma Dioscoreae Nipponicae 12-14, Radix Notoginseng 2-4, Herba Lycopodii 10-13, Radix Salviae Miltiorrhizae 5-7, Caulis Akebiae 5-10, Ramulus Cinnamomi 15-20, ophidia 6-9, Rhizoma Corydalis 5-8, Radix Cyathulae 5-7.
3. the external pulvis for the treatment of cervical spondylotic myelopathy according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: dark red mushroom 20, Fructus Leonuri 8, Rhizoma Drynariae 7, Rhizoma Dioscoreae Nipponicae 13, Radix Notoginseng 3, Herba Lycopodii 11, Radix Salviae Miltiorrhizae 6, Caulis Akebiae 7, Ramulus Cinnamomi 18 parts, ophidia 8, Rhizoma Corydalis 6, Radix Cyathulae 6.
4. the preparation method of the external pulvis of the cervical spondylotic myelopathy according to any one of claim 1-3, is characterized in that: step is as follows:
(1) decaptitated by ophidia, the block being cut into 0.5-1.5cm (preferred 1cm) puts into non iron container together with Radix Salviae Miltiorrhizae, is blended into jowar wine, soak 1-3 days, filter, filtrate is for subsequent use, gets sand and puts in hot pot, fry to sliding sharp state, drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 1-5 minute fast, takes out, sieve shakeout, spreading for cooling;
(2) by dark red mushroom, Fructus Leonuri, Rhizoma Drynariae and Rhizoma Dioscoreae Nipponicae white vinegar soak 10-20 hour (preferably 15 hours), taking-up is placed in low baking temperature on tile and is dried to savory blowing out slowly, dry in the air cool after be placed in mortar together with step (1) gained crude drug, it is stand-by to grind to form smalls;
(3) by Herba Lycopodii, Radix Salviae Miltiorrhizae, Caulis Akebiae, Ramulus Cinnamomi, Rhizoma Corydalis and Radix Cyathulae add in step (1) gained filtrate, and mixing, after slightly vexed 1-5 hour, decoct with water 2 times, intense fire is fried open for the first time, turns 10-30 minute at a simmer, filter to get filtrate 1, the low baking temperature that again adds water decocts 30-50 minute slowly, and before ceasing fire, cover lid is after slightly vexed 10 minutes, filter, obtain filtrate 2, twice filtrate is merged, must filtrate be mixed;
(4) joined by step (2) gained smalls in step (3) gained mixing filtrate, be placed in marmite, slow fire is decocted slowly, stir while decoct, in time becoming thick paste, when being placed in that on clean tile, low baking temperature dries 1-3 slowly, namely cool bottling of drying in the air obtains external pulvis.
5. the preparation method of external pulvis according to claim 4, it is characterized in that: the consumption of step (1) Sorghum vulgare Pers. Wine is that the 2-6 of the total consumption of ophidia and Radix Salviae Miltiorrhizae is doubly (preferred, the consumption of jowar wine is 3-5 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae, more preferably good, the consumption of jowar wine is 4 times of the total consumption of ophidia and Radix Salviae Miltiorrhizae).
6. the preparation method of external pulvis according to claim 4, it is characterized in that: step (1) drops into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry 2-4 minute fast, (preferably drop into the ophidia after soaking and Radix Salviae Miltiorrhizae, stir-fry fast 3 minutes).
7. the preparation method of external pulvis according to claim 4, it is characterized in that: the consumption of step (2) white vinegar is dark red mushroom, Fructus Leonuri, doubly (preferred, the consumption of white vinegar is dark red mushroom to the 1-5 of Rhizoma Drynariae and Yam total weight, Fructus Leonuri, doubly, be more added with choosing, the consumption of white vinegar is dark red mushroom for the 2-4 of Rhizoma Drynariae and Yam total weight, Fructus Leonuri, Rhizoma Drynariae and Yam total weight 3 times).
8. the preparation method of external pulvis according to claim 4, it is characterized in that: step (3) is after slightly vexed 2-4 hour, decoct with water 2 times, intense fire is fried open for the first time, turn 15-25 at a simmer minute (preferably after slightly vexed 3 hours, decoct with water 2 times, intense fire is fried open for the first time, turns 20 minutes at a simmer).
9. the preparation method of external pulvis according to claim 4, is characterized in that: step (3) low baking temperature that again adds water is decocted 35-45 minute (preferred, the low baking temperature that again adds water decocts 40 minutes slowly) slowly.
10. the preparation method of external pulvis according to claim 4, is characterized in that: step (4) is placed in low baking temperature on clean tile when drying 1.5-2.5 slowly when on clean tile, low baking temperature dries 2 slowly (preferred, be placed in).
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