CN104623042A - Composition for treating cervical spondylosis and preparation method of composition - Google Patents
Composition for treating cervical spondylosis and preparation method of composition Download PDFInfo
- Publication number
- CN104623042A CN104623042A CN201510101223.1A CN201510101223A CN104623042A CN 104623042 A CN104623042 A CN 104623042A CN 201510101223 A CN201510101223 A CN 201510101223A CN 104623042 A CN104623042 A CN 104623042A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- cervical spondylosis
- rhizoma
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a composition for treating cervical spondylosis. The composition is prepared from the following raw materials in parts by weight: 1-5 parts of dragon's bone, 1-3 parts of diclofenac sodium, 3-7 parts of biond magnolia flower bud, 2-6 parts of tuberculate speranskia herb, 4-8 parts of suberect spatholobus stem, 10-15 parts of yanhusuo, 5-15 parts of incised notopterygium, 5-10 parts of danshen, 2-4 parts of colchicine tablets, 4-8 parts of pericarpium zanthoxyli, 10-20 parts of clematis root, 5-15 parts of nux vomica, 6-16 parts of root of doubleteeth pubescent angelica and 5-10 parts of fortune's drynaria rhizome. The composition is based on the cervical spondylosis treating principle of the traditional Chinese medicine. The selected Chinese medicinal materials have the effects of benefiting qi and nourishing blood, regulating the flow of Qi and the middle Jiao, relaxing the muscles and stimulating the blood circulation, strengthening tendons and bones and treating the cervical spondylosis; the traditional Chinese medicine and Western medicine are mixed together to produce the composition for treating the cervical spondylosis; the composition is low in cost, so that a patient can use the composition for a long time without financial burden; and in short, the composition is an ideal medicine for treating the cervical spondylosis.
Description
Technical field
The invention belongs to traditional Chinese medicine field, particularly relate to a kind of composition and method of making the same for the treatment of cervical spondylosis.
Background technology
Cervical spondylosis is also known as cervical spine syndrome, it is osteoarthritis of cervical spine, the general name of proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion, it is a kind of illness changing into basis with degeneration pathology, strain for a long time mainly due to cervical vertebra, hyperosteogeny, or prolapse of intervertebral disc, ligament thickens, cause cervical vertebra spinal cord, nerve root or vertebral artery pressurized, occur a series of handicapped clinical syndrome.Show as intervertebral disc degradation itself and insecondary a series of pathological change thereof, as vertebra joint unstability, loosen; Nucleus pulposus or deviate from; Bony spur is formed; The spinal canal stenosis etc. of ligament plumpness and secondary, stimulates or has oppressed contiguous nerve root, spinal cord, the tissues such as vertebral artery and cervical region sympathetic nerve, and causing the syndrome of various sings and symptoms.
Symptom and sign: cervical spondylosis refers to degeneration of cervical intervertebral disc, cervical vertebra plump hypertrophy and neck injury etc. cause hyperosteogeny of cervical vertebra, or prolapse of intervertebral disc, ligament thicken, stimulate or compressing cervical spinal, cervical neural, blood vessel and produce the clinical syndrome of series of symptoms.Main manifestations is neck and shoulder pain, dizziness headache, upper limb numbness, amyotrophy, severe patient two lower limb spasm, difficulty in walking, even quadriplegia, and paralysis, appears in defecation obstacle.Multiple at middle-aged and elderly people, male's sickness rate is higher than women.This respect therapeutic effect is reasonable Wo Kaen.
Cardinal symptom: the symptom of cervical spondylosis is very abundant, various and complicated, most of patients starts symptom comparatively gently, increases the weight of gradually afterwards, also has partial symptoms comparatively severe one.Chang Yiyi type is that master is associated with other several type together, is called Mixed Cervical Spondylosis.Cardinal symptom is: 1, neck is takeed on to ache and can be radiated to headrest portion and upper limb; 2, side shoulder back sense of heaviness, upper myasthenia of limbs, points numb, and limb skin is felt to go down, and holds thing unable, and automatic thing of holding lands sometimes.3, its serious typical performance is: weakness of the lower extremities, and walking is unstable, and two foot numbnesses, as stepped on the sensation of Cotton Gossypii during walking.4, even quadriplegia even appears that stool, urine is out of control, sexual dysfunction, in most severe patient.5, often ache with head neck shoulder arm, neck has a stiff neck, limitation of activity.6, have with dizziness, house rotate, severe one, with nausea and vomiting, is unable to leave the bed, and minority can have dizzy, dampings off.
7, dizziness, headache, blurred vision can be there is when cervical spondylosis involves sympathetic nerve, two are swollen, dry, two Zhang Bukai, tinnitus, ear are stifled, dysequilibrium, tachycardia, nervous, the tight Bouquet sense in breast portion, even there is the symptoms such as flatulence in what have.Also dysphagia is had, the symptoms such as dysphonia.During most onset gently and be not valued by the people, majority can recover voluntarily, time light time heavy, only have when symptom continues to increase the weight of and can not reverse, just draw attention when affecting work and life.If disease obstinate, can menticide be caused, produce the symptoms such as insomnia, irritated, angry, anxiety, melancholy.
Authorization Notice No. CN 101744901 B(application number 200810231208.9) Chinese patent literature provide a kind of medicated pillow for the treatment of cervical spondylosis, be made up of pillowcase and pillow core, it is characterized in that: medicated pillow height is 7-13 centimetre, length is 30-50 centimetre; Pillow core is made up of the Chinese medicine of following weight portion: Fructus Zanthoxyli 40-60, Flos Magnoliae 40-60,2 60 ~ 80, Radix Salviae Miltiorrhizae 40-60, Semen Strychni 60-80, Rhizoma Chuanxiong 40-60, Radix Angelicae Dahuricae 40-60, Herba Menthae 60-80, Radix Aconiti Preparata 40-60, Radix Aconiti Kusnezoffii 40-60, Ramulus Cinnamomi 60-80, Radix Bupleuri 60-80, Radix Paeoniae Rubra 40-60, Camphora 25-35.Authorization Notice No. CN 103083556 B(application number 201210529270.2) Chinese patent literature provide a kind of Chinese medicine for the treatment of cervical spondylosis, it is characterized in that being made up of the component of the material medicine proportioning of following weight: Radix Puerariae 50-60g, Ramulus Cinnamomi 15-20g, Radix Paeoniae Alba 30-40g, Radix Glycyrrhizae 10-12g, Caulis Spatholobi 35-40g, Rhizoma Chuanxiong 30-35g, Semen Strychni 15-20g, Rhizoma Cibotii 30-35g, Radix Astragali 30-35g, Squama Manis pearl 10-12g, Scorpio 8-10g, Scolopendra 4-5 bar, Rhizoma Gastrodiae 15-20g, Os Draconis 30-35g, Concha Ostreae 30-35g, Pheretima 15-20g, Semen Strychni (processed) powder 0.6g.
State invention and also there are some problems in treatment cervical spondylosis: clinically to treatment cervical spondylosis, the curative effect of depressed liver-energy dispersing and QI regulating, invigorating QI and tranquilization, strengthening the tendons and bones, treatment cervical spondylosis is also undesirable.
Summary of the invention
For the present situation of existing treatment cervical spondylosis deficiency, and provide the composition and method of making the same for the treatment of cervical spondylosis, there is easy to operate, the evident in efficacy and feature had no side effect, inside of human body immunologic function can also be improved, the resistance against diseases of enhancing body, regulating the flow of Qi and the middle Jiao, the effect that YIN nourishing and QI supplementing, heat-clearing and toxic substances removing, dredging collateral are invigorated blood circulation, reducing swelling and alleviating pain, relaxing muscles and tendons to promote blood circulation play treatment cervical spondylosis.
Another object of the present invention is just to provide the preparation method of above-mentioned composition.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
The compositions for the treatment of cervical spondylosis, each crude drug is as follows, is weight portion: Os Draconis 1-5, diclofenac sodium 1-3, Flos Magnoliae 3-7, Herba speranskiae tuberculatae 2-6, Caulis Spatholobi 4-8, Rhizoma Corydalis 10-15, Rhizoma Et Radix Notopterygii 5-15, Radix Salviae Miltiorrhizae 5-10, colchicines tablets 2-4, Fructus Zanthoxyli 4-8, Radix Clematidis 10-20, Semen Strychni 5-15, Radix Angelicae Pubescentis 6-16, Rhizoma Drynariae 5-10.
The compositions for the treatment of cervical spondylosis, preferred scheme is, each crude drug is as follows, be weight portion: Os Draconis 2-4, diclofenac sodium 1.5-2.5, Flos Magnoliae 4-6, Herba speranskiae tuberculatae 4-6, Caulis Spatholobi 5-7, Rhizoma Corydalis 11-14, Rhizoma Et Radix Notopterygii 8-13, Radix Salviae Miltiorrhizae 6-9, colchicines tablets 2.5-3.5, Fructus Zanthoxyli 5-7, Radix Clematidis 13-18, Semen Strychni 8-13, Radix Angelicae Pubescentis 10-12, Rhizoma Drynariae 6-9.
The compositions for the treatment of cervical spondylosis, better preferred scheme is that each crude drug is as follows, be weight portion: Os Draconis 3, diclofenac sodium 2, Flos Magnoliae 5, Herba speranskiae tuberculatae 5, Caulis Spatholobi 6, Rhizoma Corydalis 13, Rhizoma Et Radix Notopterygii 10, Radix Salviae Miltiorrhizae 7.5, colchicines tablets 3, Fructus Zanthoxyli 6, Radix Clematidis 15, Semen Strychni 10, Radix Angelicae Pubescentis 11, Rhizoma Drynariae 7.5.
The preparation method of above-mentioned composition, step is as follows:
(1) dry clean for Os Draconis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 80-100 mesh sieve stand-by;
(2) Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar is soaked 6-16 hour, steam 20-40 minute, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 80-120 mesh sieve for subsequent use for pulverization altogether;
(3) Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, Radix Salviae Miltiorrhizae, Fructus Zanthoxyli, Radix Clematidis, Semen Strychni and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry 4-8 minute fast, and sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) diclofenac sodium and the colchicines tablets slender roll of medicated paper or gauze are pulverized, add diclofenac sodium and colchicines tablets 5-10 boiled water doubly, soak 5-10 hour; add step (1)-(3) gained smalls; little fire is heated to boiling, stirs, changes slow fire boiling 30-50 hour; leave standstill 12-16 hour; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
The preparation method of foregoing compositions, step (1) smalls crosses 85-95 mesh sieve stand-by (preferred, it is stand-by that smalls crosses 90 mesh sieves).
The preparation method of foregoing compositions, Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar soaks 9-14 hour (preferred, Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar are soaked 11 hours) by step (2).
The preparation method of foregoing compositions, step (2) steams 25-35 minute (preferred, to steam 30 minutes).
The preparation method of foregoing compositions, step (3) drops into the crude drug cut, and stir-fry 5-7 minute (preferred, to drop into the crude drug cut, stir-fry fast 6 minutes) fast.
The preparation method of foregoing compositions, step (4) adds diclofenac sodium and colchicines tablets 6-9 boiled water doubly, soaks 6-9 hour (preferred, to add the boiled water of diclofenac sodium and colchicines tablets 7.5 times, soak 8 hours).
The preparation method of foregoing compositions, step (4) little fire is heated to boiling, stirs, change slow fire boiling 35-45 hour, (preferred, little fire is heated to boiling to leave standstill 13-15 hour, stir, change slow fire boiling 40 hours, leave standstill 14 hours).
Using method: for making the present invention reach optimum therapeuticing effect, three get oral medicine 3-5ml of the present invention, warm water delivery service after the meal, and external smearing ointment spreads upon affected part, wraps with bundle, and using once before sleep every night, 7 days is a course for the treatment of.
Said composition, can not only benefiting qi and nourishing blood to the Be very effective for the treatment of cervical spondylosis, relaxing muscles and tendons to promote blood circulation, QI and blood regulating, strong muscle body-building, improves the body constitution of patient's weakness because of chronic pain, and the local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The composition and method of making the same for the treatment of cervical spondylosis, the pharmacological effect of each crude drug is respectively:
Os Draconis: Os Draconis, another name: Lu Hu loses life, that gal bone, Os Draconis, Os Draconis (calcined), five OS DRACONISs, green grass or young cropsization Os Draconis, OS DRACONIS, Os Draconis.For ancient times mammal as if the fossil of skeleton of class, rhinoceros class, Hippocampal cortex etc., tranquillization with heavy prescription tranquillizing the mind by relieving convulsion, arresting sweating controlling nocturnal emission with astringent drugs, hemostasis astringing intestine to stop diarrhea, promoting tissue regeneration and ulcer healing.Control infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, and seminal emission stranguria with turbid discharge, tell nosebleed and have blood in stool, bleeding not during menses, dysentery proctoptosis, ulcer does not close up for a long time.
Diclofenac sodium: diclofenac sodium name diclofenac, take his spirit, A meter Lei Er, Di Funa; Ao Erfen; Wet gram difficult to understand; Diclofenac; Cataflam; Novolten; It Xin Lide; Antine Capsule, indication: 1, alleviate rheumatoid arthritis, osteoarthritis.The acute attack stage of various chronic arthritis or the arthralgia symptoms of persistence such as SpA, gouty arthritis, rheumatic arthritis; 2, various soft tissue rheumatism pain, as injury pain after shoulder pain, tenosynovitis, bursitis myalgia and motion etc.; 3, acute light, moderate pain is as pain after operation, wound, strain etc.; 4, primary dysmenorrhea, toothache, headache etc.
Flos Magnoliae: Flos Magnoliae, has another name called flos magnoliae, Flos Magnoliae, Magnolia denudata Desr., Flos Magnoliae Liliflorae, Magnolia liliiflora, cajaput, Yutang spring, pungent, temperature.Attach to the lung and stomach meridians.Cold-dispelling, clearing the nasal passage.For headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge, dispels the wind, sensible.Control headache, nasal sinusitis, have a stuffy nose obstructed, toothache.
Herba speranskiae tuberculatae: sweet, acrid, warm, enters lung, liver two warp, expelling wind and removing dampness, the pungent temperature of these product, Xin Nenghang falls apart, temperature overcomes the coldness wet, relaxing muscles and tendons and activating QI and blood in the collateral, and the pungent loose temperature of these product is led to, enter Liver Channel, and liver governing tendons. therefore these product have effect of relaxing muscles and tendons and activating QI and blood in the collateral, promoting blood circulation and stopping pain, the pungent loose temperature of these product is led to, enter Liver Channel blood system, therefore energy promoting blood circulation and stopping pain, solution poisons rash.
Caulis Spatholobi: nature and flavor: bitter, sweet, temperature.Gui Jing: return liver, kidney channel.Effect: blood circulation promoting and enriching, menstruction regulating and pain relieving, relaxing muscles and tendons and activating QI and blood in the collateral.Cure mainly: for menoxenia, dysmenorrhea, amenorrhea, rheumatic arthralgia, paralysis and numbness, blood deficiency and yellow complexion.
Rhizoma Corydalis: pungent, bitter, temperature.Gui Jing returns liver, spleen channel.Effect is invigorated blood circulation, circulation of qi promoting, pain relieving.Cure mainly for the breast side of body, epigastric pain, obstruction of qi in the chest and cardialgia, amenorrhea dysmenorrhea, postpartum stagnation, tumbling and swelling.
Rhizoma Et Radix Notopterygii: nature and flavor: acrid in the mouth, hardship, warm in nature.Gui Jing enters bladder, kidney channel.Effect: induce sweat cold expelling, expelling wind and dampness, pain relieving.Cure mainly: anemofrigid cold, anemofrigid-damp arthralgia, stiffness of the nape muscular contracture, joint ache, edema due to wind pathogen edema, skin sore.
Radix Salviae Miltiorrhizae: GUIXIN, Liver Channel.Blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, clear away heart-fire relieving restlessness, and removing heat from blood eliminating carbuncle, has blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, and clear away heart-fire relieving restlessness, effect of removing heat from blood eliminating carbuncle.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen hypochondriac pain, abdominal mass abdominal mass is gathered, pyretic arthralgia pain, dysphoria and insomnia, menoxenia, and dysmenorrhea amenorrhea, skin infection swells and ache.
Colchicines tablets: colchicines tablets, indication is the acute attack for the treatment of gouty arthritis, the acute attack of prevention of recurrence gouty arthritis.
Fructus Zanthoxyli: nature and flavor: pungent, numb, temperature.Gui Jing returns spleen, stomach, kidney channel.Effect: green pepper is red: warming middle-JIAO to relieve pain, killing parasites for relieving itching.
Cure mainly: for coldness and pain in the epigastrium, vomiting is had loose bowels, abdominal pain due to worm stagnation; External treatment eczema, pudendal pruritus.
Radix Clematidis: function: have wind-damp dispelling, the effect of the meridian dredging.Cure mainly: for rheumatic arthralgia, numb limbs and tense tendons, the contracture of muscle arteries and veins, joint stuffiness.
Semen Strychni: nature and flavor: bitter, warm.Gui Jing: return liver, spleen channel.Function: have removing obstruction in the collateral to relieve pain, the effect of mass dissipating and swelling eliminating.
Cure mainly: for traumatic injury, fracture swells and ache, rheumatoid arthritis stubborn, paralysis and numbness, skin sore, laryngopharynx swelling and pain.
Radix Angelicae Pubescentis: nature and flavor: acrid in the mouth, hardship, slightly warm in nature.Gui Jing: return kidney, urinary bladder channel.Effect: expelling wind and removing dampness, arthralgia aggravated by cold pain relieving.
Cure mainly: for anemofrigid-damp arthralgia, wash pain, few cloudy volt wind headache, wind and cold holds wet headache under the arm.
Rhizoma Drynariae: the kidney invigorating bone strengthening, continues and hinders pain relieving.For lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.The kidney invigorating, invigorates blood circulation, hemostasis.Control suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus.
The present composition is based on the principle of traditional Chinese medical herbal treatment cervical spondylosis.The existing benefiting qi and nourishing blood of the Chinese medicinal material selected, effect of regulating the flow of Qi and the middle Jiao, relaxing muscles and tendons to promote blood circulation, strong muscle key bone, treatment cervical spondylosis, Chinese medicine and Western medicine are mixed the compositions being prepared into and treating cervical spondylosis, cheap, life-time service also can not cause the financial burden of patient, is to treat the ideal medicine of cervical spondylosis.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1the compositions for the treatment of cervical spondylosis, each crude drug is as follows, is weight portion (getting 10g for every part): Os Draconis 1, diclofenac sodium 1, Flos Magnoliae 3, Herba speranskiae tuberculatae 2, Caulis Spatholobi 4, Rhizoma Corydalis 10, Rhizoma Et Radix Notopterygii 5, Radix Salviae Miltiorrhizae 5, colchicines tablets 2, Fructus Zanthoxyli 4, Radix Clematidis 10, Semen Strychni 5, Radix Angelicae Pubescentis 6, Rhizoma Drynariae 5.
The preparation method of the compositions of above-mentioned treatment cervical spondylosis, step is:
(1) dry clean for Os Draconis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 80 mesh sieves stand-by;
(2) Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar are soaked 6 hours, steam 20 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 80 mesh sieves for subsequent use for pulverization altogether;
(3) Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, Radix Salviae Miltiorrhizae, Fructus Zanthoxyli, Radix Clematidis, Semen Strychni and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 4 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) diclofenac sodium and the colchicines tablets slender roll of medicated paper or gauze are pulverized, add the boiled water of diclofenac sodium and colchicines tablets 5 times, soak 5 hours; add step (1)-(3) gained smalls; little fire is heated to boiling, stirs, changes slow fire boiling 30 hours; leave standstill 12 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
embodiment 2the compositions for the treatment of cervical spondylosis, each crude drug is as follows, is weight portion (getting 15g for every part): Os Draconis 5, diclofenac sodium 3, Flos Magnoliae 7, Herba speranskiae tuberculatae 6, Caulis Spatholobi 8, Rhizoma Corydalis 15, Rhizoma Et Radix Notopterygii 15, Radix Salviae Miltiorrhizae 10, colchicines tablets 4, Fructus Zanthoxyli 8, Radix Clematidis 20, Semen Strychni 15, Radix Angelicae Pubescentis 16, Rhizoma Drynariae 10.
The preparation method of the compositions of above-mentioned treatment cervical spondylosis, step is:
(1) dry clean for Os Draconis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 100 mesh sieves stand-by;
(2) Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar are soaked 16 hours, steam 40 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 120 mesh sieves for subsequent use for pulverization altogether;
(3) Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, Radix Salviae Miltiorrhizae, Fructus Zanthoxyli, Radix Clematidis, Semen Strychni and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 8 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) diclofenac sodium and the colchicines tablets slender roll of medicated paper or gauze are pulverized, add the boiled water of diclofenac sodium and colchicines tablets 10 times, soak 10 hours; add step (1)-(3) gained smalls; little fire is heated to boiling, stirs, changes slow fire boiling 50 hours; leave standstill 16 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
typical case one:zhu XX, man, 60 years old, a machine-operated retired cadre, cervical vertebra ache is uncomfortable more than 6 years, X light sheet shows: C5, 6, 7, vertebral body has bony spur sample hypertrophy in various degree, C4, 5 intervertebral foramina stenosis, symptom: cervical vertebra upper extremity pain, stiff, two upper limb, cervical vertebra moving is limited, stomach discomfort, insomnia, through being diagnosed as cervical spondylosis, treatment by Chinese herbs two months, transfusion, Western medicine, traction, massage etc., can relief of symptoms, after aggravation again, hurt like hell, hospitalization again, with oryzanol, VB1, indometacin, compound recipe is newly bright, stimulate stomach again, gastropathy increases the weight of again, doctor advised takes the present composition.
Use and coordinate embodiment 2 resulting composition, after two courses for the treatment of, symptom alleviates, and four courses for the treatment of take a turn for the better, and 8 courses for the treatment of are almost recovered.
embodiment 3the compositions for the treatment of cervical spondylosis, each crude drug is as follows, is weight portion (getting 20g for every part): Os Draconis 2, diclofenac sodium 1.5, Flos Magnoliae 4, Herba speranskiae tuberculatae 4, Caulis Spatholobi 5, Rhizoma Corydalis 11, Rhizoma Et Radix Notopterygii 8, Radix Salviae Miltiorrhizae 6, colchicines tablets 2.5, Fructus Zanthoxyli 5, Radix Clematidis 13, Semen Strychni 8, Radix Angelicae Pubescentis 10, Rhizoma Drynariae 6.
The preparation method of the compositions of above-mentioned treatment cervical spondylosis, step is:
(1) dry clean for Os Draconis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 85 mesh sieves stand-by;
(2) Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar are soaked 9 hours, steam 25 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 90 mesh sieves for subsequent use for pulverization altogether;
(3) Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, Radix Salviae Miltiorrhizae, Fructus Zanthoxyli, Radix Clematidis, Semen Strychni and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 5 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) diclofenac sodium and the colchicines tablets slender roll of medicated paper or gauze are pulverized, add the boiled water of diclofenac sodium and colchicines tablets 6 times, soak 6 hours; add step (1)-(3) gained smalls; little fire is heated to boiling, stirs, changes slow fire boiling 35 hours; leave standstill 13 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
embodiment 4the compositions for the treatment of cervical spondylosis, each crude drug is as follows, is weight portion (getting 25g for every part): Os Draconis 4, diclofenac sodium 2.5, Flos Magnoliae 6, Herba speranskiae tuberculatae 6, Caulis Spatholobi 7, Rhizoma Corydalis 14, Rhizoma Et Radix Notopterygii 13, Radix Salviae Miltiorrhizae 9, colchicines tablets 3.5, Fructus Zanthoxyli 7, Radix Clematidis 18, Semen Strychni 13, Radix Angelicae Pubescentis 12, Rhizoma Drynariae 9.
The preparation method of the compositions of above-mentioned treatment cervical spondylosis, step is:
(1) dry clean for Os Draconis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 95 mesh sieves stand-by;
(2) Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar are soaked 14 hours, steam 35 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 110 mesh sieves for subsequent use for pulverization altogether;
(3) Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, Radix Salviae Miltiorrhizae, Fructus Zanthoxyli, Radix Clematidis, Semen Strychni and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 7 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) diclofenac sodium and the colchicines tablets slender roll of medicated paper or gauze are pulverized, add the boiled water of diclofenac sodium and colchicines tablets 9 times, soak 9 hours; add step (1)-(3) gained smalls; little fire is heated to boiling, stirs, changes slow fire boiling 45 hours; leave standstill 15 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
typical case two:zheng XX, man, 58 years old, cervical vertebra motion is uncomfortable more than 5 years, and X light sheet shows: cervical vertebrae physiological is bending to be changed, and bends to the left, C4,5 intervertebral spaces are broadening to the right, left side narrows, and X mating plate is diagnosed: cervical vertebra lateral bending, vertebral body C4,5 intervertebral disk hernia, symptom: cervical nerve root compression, upper limb, the amyotrophy of size border, lax, function limitation, cause maimed person, doctor advised takes the present composition.
Use and coordinate embodiment 4 resulting composition, after 5 courses for the treatment of, patient's symptom that feels uneasy alleviates, and sleep also obviously improves, and after 8 courses for the treatment of, the symptom of patient all disappears.
embodiment 5the compositions for the treatment of cervical spondylosis, each crude drug is as follows, is weight portion (getting 30g for every part): Os Draconis 3, diclofenac sodium 2, Flos Magnoliae 5, Herba speranskiae tuberculatae 5, Caulis Spatholobi 6, Rhizoma Corydalis 13, Rhizoma Et Radix Notopterygii 10, Radix Salviae Miltiorrhizae 7.5, colchicines tablets 3, Fructus Zanthoxyli 6, Radix Clematidis 15, Semen Strychni 10, Radix Angelicae Pubescentis 11, Rhizoma Drynariae 7.5.
The preparation method of the compositions of above-mentioned treatment cervical spondylosis, step is:
(1) dry clean for Os Draconis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 90 mesh sieves stand-by;
(2) Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar are soaked 11 hours, steam 30 minutes, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 100 mesh sieves for subsequent use for pulverization altogether;
(3) Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, Radix Salviae Miltiorrhizae, Fructus Zanthoxyli, Radix Clematidis, Semen Strychni and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry fast 6 minutes, sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) diclofenac sodium and the colchicines tablets slender roll of medicated paper or gauze are pulverized, add the boiled water of diclofenac sodium and colchicines tablets 7.5 times, soak 8 hours; add step (1)-(3) gained smalls; little fire is heated to boiling, stirs, changes slow fire boiling 40 hours; leave standstill 14 hours; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
experimental example (embodiment 5 resulting composition):in order to verify the effect of the present composition, we have extracted 600 patients in 4 hospitals and have carried out the experiment of medicine, test group 300 people, matched group 300 people, and experimental group uses embodiment 5 resulting composition, and matched group uses the medicine of other treatment cervical spondylosis.Inclusion criteria: through being diagnosed as Patients with Cervical Spondylopathy, has treatment cervical spondylosis clinical symptoms one or more.Using method: for making the present invention reach optimum therapeuticing effect, three get oral medicine 3-5ml of the present invention, warm water delivery service after the meal, and external smearing ointment spreads upon affected part, wraps with bundle, and using once before sleep every night, 7 days is a course for the treatment of.Curative effect situation criterion: 1, cure, after using this product, malaise symptoms disappears completely; 2, effective, after using this product, malaise symptoms alleviates or partial disappearance; 3, invalid, after using this product, malaise symptoms is unchanged.We have carried out accurate statistics and mathematical analysis to experimental data.Specific experiment result is as following table:
Table 1: two groups of Clinical efficacy comparison [example] tables 1
Self-induction symptom and emotion changes result are as table 2:
Table 2:
Prove through clinical trial, the present composition is in treatment cervical spondylosis, and effective percentage is 95%, and thoroughly can remove old complaint, treating both the principal and secondary aspects of a disease, makes the recovery from illness that patient is real; And any burden can not be caused to the health of patient.Present composition instant effect, can reach the object alleviating rapidly patient's misery, and relapse rate is low, is a kind of composition and method of making the same of the treatment for the treatment of safely and effectively cervical spondylosis.
The composition and method of making the same for the treatment of cervical spondylosis, wherein Radix Clematidis, Radix Angelicae Pubescentis do monarch, and ministerial drug is Rhizoma Corydalis, Rhizoma Et Radix Notopterygii and Semen Strychni, and remaining is adjuvant drug; Monarch drug carries attending effectiveness in the present invention, all has effect of benefiting qi and nourishing blood, relaxing muscles and tendons to promote blood circulation, strong muscle key bone-specific drug cervical spondylosis; Ministerial drug is the medicine that auxiliary monarch drug strengthens the main disease for the treatment of and main symptom; Adjuvant drug treatment is held concurrently disease, slows down the strong of monarch drug and ministerial drug; Medicine is made to play a part guiding drug.
Claims (10)
1. treat the compositions of cervical spondylosis, it is characterized in that: each crude drug is as follows, is weight portion: Os Draconis 1-5, diclofenac sodium 1-3, Flos Magnoliae 3-7, Herba speranskiae tuberculatae 2-6, Caulis Spatholobi 4-8, Rhizoma Corydalis 10-15, Rhizoma Et Radix Notopterygii 5-15, Radix Salviae Miltiorrhizae 5-10, colchicines tablets 2-4, Fructus Zanthoxyli 4-8, Radix Clematidis 10-20, Semen Strychni 5-15, Radix Angelicae Pubescentis 6-16, Rhizoma Drynariae 5-10.
2. the compositions for the treatment of cervical spondylosis according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Os Draconis 2-4, diclofenac sodium 1.5-2.5, Flos Magnoliae 4-6, Herba speranskiae tuberculatae 4-6, Caulis Spatholobi 5-7, Rhizoma Corydalis 11-14, Rhizoma Et Radix Notopterygii 8-13, Radix Salviae Miltiorrhizae 6-9, colchicines tablets 2.5-3.5, Fructus Zanthoxyli 5-7, Radix Clematidis 13-18, Semen Strychni 8-13, Radix Angelicae Pubescentis 10-12, Rhizoma Drynariae 6-9.
3. the compositions for the treatment of cervical spondylosis according to claim 1, is characterized in that: each crude drug is as follows, is weight portion: Os Draconis 3, diclofenac sodium 2, Flos Magnoliae 5, Herba speranskiae tuberculatae 5, Caulis Spatholobi 6, Rhizoma Corydalis 13, Rhizoma Et Radix Notopterygii 10, Radix Salviae Miltiorrhizae 7.5, colchicines tablets 3, Fructus Zanthoxyli 6, Radix Clematidis 15, Semen Strychni 10, Radix Angelicae Pubescentis 11, Rhizoma Drynariae 7.5.
4. the preparation method of the compositions of the treatment cervical spondylosis according to any one of claim 1-3, is characterized in that: step is as follows:
(1) dry clean for Os Draconis, pinion with iron wire, big fire bake is crisp, grinds to form smalls, crosses 80-100 mesh sieve stand-by;
(2) Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar is soaked 6-16 hour, steam 20-40 minute, dryouied by large iron pan, rapidly drop into steamed crude drug, parch is flavoursome when sending, and cools, and to cross 80-120 mesh sieve for subsequent use for pulverization altogether;
(3) Rhizoma Corydalis, Rhizoma Et Radix Notopterygii, Radix Salviae Miltiorrhizae, Fructus Zanthoxyli, Radix Clematidis, Semen Strychni and Rhizoma Drynariae are cleaned, dry, be cut into small pieces, be placed in by wheat bran in marmite, the sliding sharp state of parch, drops into the crude drug cut, stir-fry 4-8 minute fast, and sieve removes wheat bran, and it is stand-by crude drug to be ground to form smalls;
(4) diclofenac sodium and the colchicines tablets slender roll of medicated paper or gauze are pulverized, add diclofenac sodium and colchicines tablets 5-10 boiled water doubly, soak 5-10 hour; add step (1)-(3) gained smalls; little fire is heated to boiling, stirs, changes slow fire boiling 30-50 hour; leave standstill 12-16 hour; get supernatant, supernatant is boiled and adds white sugar to boiling, cease fire after white sugar melts fully completely; cool rear bottling and namely obtain oral medicine, residue medicinal residues are bottled and obtain external smearing ointment.
5. the preparation method of compositions according to claim 4, is characterized in that: step (1) smalls crosses 85-95 mesh sieve stand-by (preferred, it is stand-by that smalls crosses 90 mesh sieves).
6. the preparation method of compositions according to claim 4, it is characterized in that: Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar soak 9-14 hour (preferred, Flos Magnoliae, Herba speranskiae tuberculatae, Caulis Spatholobi and Radix Angelicae Pubescentis white vinegar are soaked 11 hours) by step (2).
7. the preparation method of compositions according to claim 4, is characterized in that: step (2) steams 25-35 minute (preferred, to steam 30 minutes).
8. the preparation method of compositions according to claim 4, is characterized in that: step (3) drops into the crude drug cut, and stir-fry 5-7 minute (preferred, to drop into the crude drug cut, stir-fry fast 6 minutes) fast.
9. the preparation method of compositions according to claim 4, it is characterized in that: step (4) adds diclofenac sodium and colchicines tablets 6-9 boiled water doubly, soak 6-9 hour (preferred, to add the boiled water of diclofenac sodium and colchicines tablets 7.5 times, soak 8 hours).
10. the preparation method of compositions according to claim 4, it is characterized in that: step (4) little fire is heated to boiling, stir, change slow fire boiling 35-45 hour, (preferred, little fire is heated to boiling, stirs to leave standstill 13-15 hour, change slow fire boiling 40 hours, leave standstill 14 hours).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510101223.1A CN104623042A (en) | 2015-03-09 | 2015-03-09 | Composition for treating cervical spondylosis and preparation method of composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510101223.1A CN104623042A (en) | 2015-03-09 | 2015-03-09 | Composition for treating cervical spondylosis and preparation method of composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104623042A true CN104623042A (en) | 2015-05-20 |
Family
ID=53202604
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510101223.1A Pending CN104623042A (en) | 2015-03-09 | 2015-03-09 | Composition for treating cervical spondylosis and preparation method of composition |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104623042A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112353930A (en) * | 2020-11-20 | 2021-02-12 | 刘昌贵 | Shoulder, neck and waist health care liquid |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757148A (en) * | 2008-12-24 | 2010-06-30 | 天津市中宝制药有限公司 | Traditional Chinese medicine composition for treating cervical spondylosis |
-
2015
- 2015-03-09 CN CN201510101223.1A patent/CN104623042A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101757148A (en) * | 2008-12-24 | 2010-06-30 | 天津市中宝制药有限公司 | Traditional Chinese medicine composition for treating cervical spondylosis |
Non-Patent Citations (1)
| Title |
|---|
| 祝林堂: "自拟颈痛灵方治疗颈椎病50例", 《陕西中医》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112353930A (en) * | 2020-11-20 | 2021-02-12 | 刘昌贵 | Shoulder, neck and waist health care liquid |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105709021A (en) | Muscle and bone recovery unguent and preparation method thereof | |
| CN104083457B (en) | The preparation method for the treatment of deficiency of vital energy and physically weak type lumbar muscle strain orthopaedics medicated wine | |
| CN103316146A (en) | Traditional Chinese medicinal preparation for anesthesia | |
| CN104069474A (en) | Traditional Chinese medicine composition for treating seborrheic alopecia and preparation method thereof | |
| CN103977217A (en) | Medicinal composition for treating renal carcinoma | |
| CN103893670B (en) | Traditional Chinese medicine pill used for treating cardia-cerebrovascular diseases | |
| CN105343865A (en) | Medicine for treating nervous vomiting and preparation method of medicine | |
| CN105031013A (en) | Medicine for treating lumbar vertebrae bone hyperplasia and preparation method thereof | |
| CN104173776A (en) | Pharmaceutical preparation for treating cervicogenic headache and preparation method of pharmaceutical preparation | |
| CN104623042A (en) | Composition for treating cervical spondylosis and preparation method of composition | |
| CN105362914A (en) | Traditional Chinese medicinal composition for treating chronic gastritis | |
| CN104173771A (en) | Lucidity-ascending and turbidity-descending traditional Chinese medicine composition for treating aural vertigo and preparation method thereof | |
| CN104984280A (en) | Foot soaking decoction for treating exogenous wind-cold and preparation method thereof | |
| CN104689240A (en) | Medicine for treating Qi-stagnation and blood stasis type chloasma and preparation method thereof | |
| CN104173775A (en) | Traditional Chinese medicine composition for treating cervicogenic headache and preparation method of traditional Chinese medicine composition | |
| CN104225128A (en) | Pharmaceutical preparation for relieving headache caused by cervical spondylosis and preparation method of pharmaceutical preparation | |
| CN103341054B (en) | Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and preparation method thereof | |
| CN101757469B (en) | Medicament for treating rheumatoid arthritis and preparation method thereof | |
| CN105381409A (en) | Medicine for treating cholelithiasis and preparation method of medicine | |
| CN104606384A (en) | Composition for treating back and leg pain and preparation method for composition | |
| CN104606537A (en) | Qi-reinforcing and blood-nourishing medicated diet for improving chemotherapy-induced myocardial ischemic injury and preparation method | |
| CN105194518A (en) | Traditional Chinese medicine for treating neurogenic endocrine dysfunction | |
| CN105012656A (en) | Chinese herbal medicine solution capable of curing cervical spondylosis, arthritis and osteoproliferation and preparation method of Chinese herbal medicine solution | |
| CN104306930A (en) | Traditional Chinese medicine formula for treating severe acute pancreatitis and preparation method of traditional Chinese medicine formula | |
| CN104352767A (en) | Traditional Chinese medicine for treating cervicogenic headache |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150520 |
|
| RJ01 | Rejection of invention patent application after publication |