CN101757469B - Medicament for treating rheumatoid arthritis and preparation method thereof - Google Patents

Abstract

The invention discloses a medicament for treating rheumatoid arthritis. The medicament is mainly prepared from antler, cibot rhizome, teasel root, pericarpium citri reticulatae, earthworm, nux vomica, largeleaf gentian root, centipede, pawpaw, notoginseng and hemlock parsley according to a certain proportioning by weight. The medicament can be prepared into any commonly-used oral medicament excipient. The medicament has the functions of invigorating marrow, assisting kidney yang, freeing channels, quickening network vessels, dispersing pathogenic wind and relieving pains and is used for treating rheumatoid arthritis with good curative effect and high cure rate.

Description

A kind of medicine of treating rheumatic arthritis and preparation method thereof

Technical field:

The present invention relates to a kind of medicine of treating rheumatic arthritis, belong to the field of Chinese medicines.

Background technology:

Rheumatic arthritis is one of a kind of common clinical, frequently-occurring disease; All weak, insufficiency of vital energy and blood because of human body constitution or overwork, the skin pore is loose, the Wei Bugu of battalion, exopathogen is taken advantage of a weak point; Multiple abscess meridians, muscle, joint; Cause coagulation of QI-blood, blocking barrier, stagnation of QI and blood may bring about pain and arthralgia, activity disadvantageous situation occur.Western medical treatment how with bigcatkin willow acid supplement and anti-inflammation analgesia medicine with alleviating pain, diminish inflammation, but the salicylic acid preparation often has the gastric irritation symptom, toxicity phenomenons such as vomiting, inappetence, epigastrium pain and gastrorrhagia, tinnitus, deafness, giddy are prone to cause nausea.

Summary of the invention:

Therefore there is great demand in people to the medicine of curative effect Chinese medicine preparation treatment preferably rheumatic arthritis; Up to now; Also do not find the relevant report about medicine of the present invention, the inventor is through research repeatedly, and the repeated validation through animal and clinical trial; Finally work out the oral medicinal herb medicine that the treatment of better curative effect rheumatic arthritis is arranged, thereby accomplished the present invention.

The purpose of this invention is to provide a kind of Chinese medicine composition of more effectively treating rheumatic arthritis.

Another object of the present invention has just provided the method for preparing of this Chinese medicine composition.

Medicine of the present invention selects Cornu Cervi Pantotrichum, Rhizoma Cibotii, Radix Dipsaci, Pericarpium Citri Reticulatae, Pheretima, Semen Strychni, Radix Achyranthis Bidentatae, Herba Cayatiae Japonicae, Radix Clematidis, Rhizoma Gastrodiae, Scorpio, Bombyx Batryticatus, Fructus Psoraleae, Radix Glycyrrhizae, Olibanum, Radix seu herba Heteropogonis Contorti, Radix Angelicae Sinensis, Myrrha, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, Radix Gentianae Macrophyllae, Scolopendra, Fructus Chaenomelis, Radix Notoginseng, the Cortex Eucommiae, Ramulus Cinnamomi and Flos Carthami to make up; With these drug regimens; Make each efficacy of drugs produce synergism; Thereby can effectively treat the recurrence of rheumatic arthritis; Wherein select for use Cornu Cervi Pantotrichum to be because Cornu Cervi Pantotrichum is mended marrow, help kidney yang, strengthening the tendons and bones.Control suffer from a deficiency of the kidney, dizzy, deaf, disease such as order is dark, sexual impotence, seminal emission, waist knee flaccidity, deficiency and coldness leukorrhagia and prolonged illness are deficient.Select for use Rhizoma Cibotii to be because the Rhizoma Cibotii nature and flavor are bitter, sweet, warm, return liver, kidney channel, invigorating the liver and kidney removes rheumatism, strong waist foot, and aching pain in waist and back is controlled in sharp joint, the gonalgia flaccidity of the lower limbs, the solid numbness of cold-damp is lost and is drowned, frequent micturition, seminal emission, deficiency-cold of uterus, bleeding not during menses.Select for use Radix Dipsaci to be because the Radix Dipsaci nature and flavor are bitter, arduous, tepor is returned liver, kidney channel.Tonifying liver is virtuous, bone and muscle strengthening, and continuous folding is hindered, and ends metrorrhagia, and it is soft to be used for the waist urushic acid, rheumatic arthralgia, metrorrhagia, vaginal bleeding during pregnancy, traumatic injury.Select for use Pericarpium Citri Reticulatae to be because the Pericarpium Citri Reticulatae nature and flavor are bitter, cold, poisonous, return lung, spleen channel is regulated the flow of vital energy and is transferred, and drying dampness to eliminate phlegm cures mainly steam rapids stagnant gastral cavity abdominal distention of taste.Select for use Pheretima to be because the Pheretima nature and flavor are salty-cold, heat clearing away, spasmolytic, diuresis, detoxifcation.Select for use Semen Strychni to be because the Semen Strychni nature and flavor are bitter, cold, poisonous, return liver, spleen two warps, removing obstruction in the collateral to relieve pain is arranged, the function of mass dissipating and swelling eliminating is used for the rheumatoid arthritis stubborn paralysis and numbness, traumatic injury, ulcer sore pain; Poliomyelitis sequela, rheumatoid arthritis.Paralysis and numbness, myasthenia gravis etc.It is sweet, bitter, sour because of the Radix Achyranthis Bidentatae nature and flavor, flat selecting Radix Achyranthis Bidentatae for use, returns liver, kidney channel.Invigorating the liver and kidney is arranged, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, it is descending to draw enemy state's (fire), the function of inducing diuresis for treating stranguria syndrome cures mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis, note of the ancient Chinese abdominal mass, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain.Select Herba Cayatiae Japonicae for use, have another name called Cortex Acanthopancis, the thorn bent stick, the Herba Cayatiae Japonicae acrid in the mouth, little hardship, slightly warm in nature is returned spleen, kidney, heart channel, cures mainly anemofrigid-damp arthralgia, and the muscles and bones contraction is anxious, lumbago, sexual impotence, flaccidity of the lower limbs beriberi, skin ulcer cellulitis toxic swelling, traumatic injury impairment caused by overstrain.Replenishing QI to invigorate the spleen, tonifying the kidney for tranquilization, for spleen kidney yang deficiency, body void is weak, inappetence, soreness of waist and knee joint.Select for use Radix Clematidis to be because the Radix Clematidis nature and flavor are hot, salty, temperature, poisonous, return through, go into urinary bladder channel, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the hypochondriac lump of loosing.Cure mainly gout insensitive impediment, rheumatic arthralgia, numb limbs and tense tendons, waist lacquer cold type of pain, the contracture of muscle arteries and veins, joint stuffiness, beriberi, malaria, lump in the abdomen, tetanus, tonsillitis, all a fishbone or other bone caught in the throat pharynxs.Select for use Rhizoma Gastrodiae to be because the Rhizoma Gastrodiae nature and flavor are sweet flat, go into Liver Channel, the function of endogenous wind stopping analgesic therapy is arranged, control dizzy pupil, wind syndrome of head headache, numb limbs and tense tendons, hemiplegia.Select Scorpio for use, have another name called Scorpio, Scorpio, Scorpio, the Scorpio nature and flavor are hot, and are flat, poisonous, return Liver Channel.Endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.Be used for infantile convulsion, the tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.Select Bombyx Batryticatus for use, have another name called, Bombyx Batryticatus, flying worm, Bombyx Batryticatus, Bombyx Batryticatus, Bombyx Batryticatus nature and flavor suffering is salty, and is flat, goes into liver, lung meridian, the stomach warp, expelling wind to relieve convulsion, apoplectic aphasia is controlled in dissipating phlegm and resolving masses, infantile convulsion, wind syndrome of head, acute throat trouble, sore throat, scrofula tuberculosis, wind skin ulcer urticaria, erysipelas, mastitis.Select for use Fructus Psoraleae to be because Fructus Psoraleae is returned through, kidney, pericardium, spleen, stomach, lung meridian, acrid in the mouth, hardship, nature and flavor, kidney deficiency, below element deficiency and cold, chills and pain of the waist and kness, sexual impotence is smart, frequent urination and enuresis, failure of the kidney in receiving QI, the more than asthenia of both the spleen and kidney of dyspnea due to deficiency, the stool chronic diarrhea, vitiligo, it is bald to change the king, psoriasis.Select for use the Radix Glycyrrhizae nature and flavor sweet, flat, go into spleen, stomach, lung meridian, the Radix Glycyrrhizae invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription is used for weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, gastral cavity abdomen, the anxious pain of extremity contraction, carbuncle sore tumefacting virus.Select for use Olibanum to be because the Olibanum nature and flavor are arduous, warm, return through, go into the heart, liver, spleen channel, regulating qi and activating blood, analgesic therapy chases after poison, controls coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.Select Radix seu herba Heteropogonis Contorti for use, have another name called native muscle, nature and flavor, sweet cold relieve heat and thirst, and the function of expelling wind and removing dampness is treated calentura and quenched one's thirst, coughs, and vomits and diarrhoea arthralgia.Select for use Radix Angelicae Sinensis to be because Radix Angelicae Sinensis property is ignorant, sweet, hot, warm, return liver, heart spleen channel, enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, the function of loosening bowel to relieve constipation is used for blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, rheumatic arthralgia, traumatic injury, carbuncle lump infections.Select for use Myrrha to be because the Myrrha nature and flavor are bitter, hot, flat, cure mainly traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.Selecting Radix Angelicae Pubescentis for use is that acrid in the mouth, hardship are returned kidney, urinary bladder channel, wind-damp dispelling, numbness relieving and pain relieving because of the Radix Angelicae Pubescentis slightly warm in nature.Be used for anemofrigid-damp arthralgia, lumbocrural pain.Select for use Rhizoma Chuanxiong to be because the Rhizoma Chuanxiong nature and flavor are hot, warm, return liver, gallbladder, pericardium channel, the sector-style of invigorating blood circulation, wind-expelling pain-stopping.Be used to pacify nerve, positive wind syndrome of head headache, lump in the abdomen stomachache, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.Select for use Radix Gentianae Macrophyllae to be because the Radix Gentianae Macrophyllae nature and flavor are hot, bitter, flat, return stomach, liver, gallbladder meridian, wind-damp dispelling, clearing away damp-heat, stopping numbness pain is used for rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, infantile malnutrition heating.Select for use Scolopendra to be because the Scolopendra nature and flavor are hot, temperature, poisonous, return Liver Channel, endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain is used for infantile convulsion, the tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.Select for use Fructus Chaenomelis to be because the Fructus Chaenomelis nature and flavor are sour, temperature is returned liver, spleen channel, the suppressing the hyperactive liver Shujin, and the stomach function regulating removing dampness is used for the arthralgia chiefly caused by damp pathogen contracture, the heavy pain of waist knee joint acid, the convulsion of vomiting and diarrhoea, beriberi edema.Select for use Radix Notoginseng to be because Radix Notoginseng is warm in nature, sweet in the mouth, little hardship, the little hardship of bitter in the mouth, warm in nature, return liver, the stomach warp, dissipating blood stasis hemostasis, subduing swelling and relieving pain, be used for various inside and outside hemorrhage, breast ventral spine pain, tumbling and swelling.Selecting the Cortex Eucommiae for use is that temperature is gone into liver, kidney channel, urinary bladder channel because of the sweet little suffering of Cortex Eucommiae nature and flavor, invigorating the liver and kidney, and bone and muscle strengthening, antiabortive, control the spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is desired to fall, frequent fetal movement, hypertension.Select for use Ramulus Cinnamomi to be because the Ramulus Cinnamomi nature and flavor are hot, sweet, warm, GUIXIN, lung, urinary bladder channel, the diaphoresis expelling pathogenic factors from muscles, temperature ability passages through which vital energy circulates, supporing yang activating QI, the flat gas that spins is used for anemofrigid cold, coldness and pain in the epigastrium, cold in blood amenorrhea, arthralgia, phlegm retention, edema, cardiopalmus, renal mass.Select for use Flos Carthami to be because Flos Carthami is warm in nature, acrid in the mouth is gone into the heart, Liver Channel, promoting blood circulation to restore menstrual flow, and eliminating stasis to stop pain is used for that amenorrhea, dysmenorrhea, lochia are not all right, lump in the abdomen mass in the abdomen, traumatic injury.

The amounts of components of medicine of the present invention also is to draw through the Test Summary of inventor through repeatedly, and amount of drug all has curative effect preferably in following weight range:

Preferable amount is:

One, the process of preparing Chinese medicine of crude drug:

1, Cornu Cervi Pantotrichum: burn hair with fire, behind the sheet glass scraping, twine with strap, pour in base apertures with hot Chinese liquor, constantly add wine, till running through, section is dried after the pressing;

2, Rhizoma Cibotii: get sand and put the interior stir-fry of pot to easily, add and choose clean Rhizoma Cibotii, stir-fry with high heat is to heaving and apparent buff taking-up; Screen out sand, after wind dries in the air, hit or the yellow fine hair of scraping, or clean former medicine soaked 12 hours with clear water after scraping QUMAO; Put into food steamer and steamed one day, at a stewing night, system is black to be degree; Turn over up and down and steam one day again, at a stewing night, taking-up is dried;

3, Radix Dipsaci: washing, remove the retained root head, it is anti-dandruff that dry screen is shone in section after running through;

4, Pericarpium Citri Reticulatae: clean system is removed impurity, cuts insect water spray, runs through shredding and dries in the shade;

5, Pheretima: remove clean impurity, dry;

6, Semen Strychni: get sand, put in the pot and make popular, add and choose clean Semen Strychni, fry to being buff and heaving, take out, sieve removes sand, scrapes QUMAO, levigation;

7, Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;

8, Herba Cayatiae Japonicae: spring, autumn excavate, and remove earth, dry;

9, Radix Clematidis: choose decontamination, remove residual stem, be soaked in water, pull out and run through, cutting is dried;

10, Rhizoma Gastrodiae: choose decontamination, big or small stepping is soaked in water to pull out slightly thoroughly to seventy percent and dries in the air, and moistens to internal and external temperature evenly again, and section is dried;

11, Scorpio: remove impurity, cleaning, drying;

12, Bombyx Batryticatus: choose the silk hair, clean dirt, dry;

13, Fructus Psoraleae: the clean impurity of winnowing with a dustpan, clean, dry;

14, Radix Glycyrrhizae: remove impurity, clean, run through, cut sheet, drying;

15, Olibanum: choose clean Olibanum, put in the pot and see melting point slightly with slow fire to surface, slightly be yellow, taking-up cools, or when frying to surface melting, sprays rice vinegar, continue to fry to layer bright light thoroughly, taking-up cools;

16, Radix seu herba Heteropogonis Contorti: remove residual stem, clean and dry all herbal medicine;

17, Radix Angelicae Sinensis: get crude drug, remove impurity, wash quickly is clean, runs through shave, cold drying;

18, Myrrha: get the Myrrha of choosing clean and put in the pot to fry with slow fire and see melting point slightly to the surface, taking-up cools;

19, Radix Angelicae Pubescentis: remove impurity, clean, run through, shave dries or cold drying;

20, Rhizoma Chuanxiong: remove impurity, separately size is slightly steeped, and cleans, and runs through shave, drying;

21, Radix Gentianae Macrophyllae: choose decontamination, remove removing LU, soak slightly, run through section, dry;

22, Scolopendra: choose clean, remove cephalopodium, cut off usefulness;

23, Fructus Chaenomelis: clean, run through or steam shave afterwards, dry;

24, Radix Notoginseng: choose clean impurity, smash to pieces, grind into powder;

25, the Cortex Eucommiae: remove rough bark, clean, run through, dice or strand dry;

26, Ramulus Cinnamomi: water soaks slightly, picks up stewing profit to passing through, and section is dried, and sieves anti-dandruff;

27, Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry.

Two, the preparation of honeyed pill:

1, above-mentioned raw materials medicine mixing and stirring porphyrize powder is crossed 200 order dusting covers;

2, Mel is refined into 110-115 ℃ tender honey;

3, will grind for the spice of fine powder by weight 1: 1 ratio add mixed sticking together in the Mel, rubbing pill again, every ball contains pure medicine 1 gram;

4, in process for preparation in order to prevent that pill from adhering to instrument, smear a small amount of " pill oil ";

5, the preparation of pill oil: add the Cera Flava preparation with vegetable oil, its preparation weight ratio is all could in 4: 1 or 5: 1.

Three, capsular preparation:

1, above-mentioned raw materials medicine mixed together is stirred, grind and be fine powder, cross 200 order dusting covers, be made as thin medicated powder;

2, fine powder medicated powder is incapsulated, every 0.4 restrains or is prepared into tablet or powder.

Medicine of the present invention has benefit marrow, helps kidney yang, dredge the meridian passage; Strengthening the tendons and bones; The function of wind-expelling pain-stopping is used to treat rheumatic arthritis, pain in the lumbar region skelalgia, numb limbs and tense tendons, traumatic injury, sciatica, apoplexy, hemiplegia, rheumatism and rheumatoid arthrosis pain good effect, and cure rate is high.

Below come further to set forth medicine of the present invention through Test Example effective effect, these Test Example comprise that the test of pesticide effectiveness of medicine of the present invention and clinical observation on the therapeutic effect test.

(Test Example 1) animal toxicity test

Get 20 of new zealand rabbits, the male and female dual-purpose, body weight 2.0-2.5kg is divided into two groups, and 10 every group, wherein one group is the toxicity trial group of excess, and another group is the toxicity trial group of normal amount.

Medicated powder is mixed with suspension with distilled water diluting, adopts the administration by gavage administration, excess group dosage is per kilogram of body weight medication powder 0.3 gram; Normal amount group dosage is per kilogram of body weight medication 0.05 gram; The secondary serve on 7 days, observes two groups of rabbit response situation after the medication every day.

After the excess group was taken medicine, wherein 2 looks dull in 10 rabbits, and inappetence recovers normal after three hours.After the normal amount group was taken medicine, 10 rabbit crowds did not have any untoward reaction.The result shows that medicine of the present invention is taken and had no side effect in the normal amount scope.

The clinical observation material of (Test Example 2) Drug therapy rheumatic arthritis disease of the present invention

1, physical data

Accept out-patient's 76 examples for medical treatment, wherein male 45 examples, women 31 examples, age 16-30 year 6 examples, 31-40 year 11 examples, 41-50 year 23 examples, 36 examples more than 50 years old.

2, diagnostic criteria

Acute rheumatic arthritis: clinical manifestation is the unexpected malaise of patient, arthralgia, and the bilateral knee redness and swelling of joints, expression is painful, and spirit is poor.

Rheumatic arthritis: the patient has the rheumatism medical history, the lighter's sore waist and aching in the waist and the back, and weight person's redness and swelling of joints, stiff, two kneecap arthroncuss, the little redness and swelling of joints distortion of extremity can not be walked, and less patient suffering face spirit is poor, very overcast and rainy.

3, Therapeutic Method

Every day secondary, each 2.5-3 gram, eliminating cold for resuscitation water or Chinese liquor take for one cup, two months is a course of treatment, serve on 2-3 the course of treatment, 12 one full year of life, following child was forbidden.

4, efficacy assessment standard

Produce effects: behind drug treatment, various transference cures, it is normal that body constitution is recovered, and observes 1 year no recidivist;

Take a turn for the better: the state of an illness is clearly better, and redness fades away, and joint movement function recovers, and the joint of swelling dwindles as usual;

Invalid: as not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In an above-mentioned 2-3 course of therapy, with Drug therapy acute rheumatic arthritis patient 19 examples of the present invention, produce effects 17 examples wherein, 2 examples that take a turn for the better, obvious effective rate is 89.47%, and improvement rate is 10.53%, and total effective rate is 100%.Treatment rheumatic arthritis patient 57 examples, produce effects 48 examples wherein, 5 examples that take a turn for the better, invalid 4 examples, obvious effective rate is 84.21%, and improvement rate is 8.77%, and total effective rate is 92.98%.

Claims (4)

1. medicine of treating rheumatic arthritis, it is characterized in that: it is to be processed by the crude drug in the following weight range:

The process of preparing Chinese medicine of crude drug:

(1) Cornu Cervi Pantotrichum: burn hair with fire, behind the sheet glass scraping, twine with strap, pour in base apertures with hot Chinese liquor, constantly add wine, till running through, section is dried after the pressing;

(2) Rhizoma Cibotii: get sand and put the interior stir-fry of pot to easily, add and choose clean Rhizoma Cibotii, stir-fry with high heat is to heaving and apparent buff taking-up; Screen out sand, after wind dries in the air, hit or the yellow fine hair of scraping, or clean former medicine soaked 12 hours with clear water after scraping QUMAO; Put into food steamer and steamed one day, at a stewing night, system is black to be degree; Turn over up and down and steam one day again, at a stewing night, taking-up is dried;

(3) Radix Dipsaci: washing, remove the retained root head, it is anti-dandruff that dry screen is shone in section after running through;

(4) Pericarpium Citri Reticulatae: clean system is removed impurity, cuts insect water spray, runs through shredding and dries in the shade;

(5) Pheretima: remove clean impurity, dry;

(6) Semen Strychni: get sand, put in the pot and make popular, add and choose clean Semen Strychni, fry to being buff and heaving, take out, sieve removes sand, scrapes QUMAO, levigation;

(7) Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;

(8) Herba Cayatiae Japonicae: spring, autumn excavate, and remove earth, dry;

(9) Radix Clematidis: choose decontamination, remove residual stem, be soaked in water, pull out and run through, cutting is dried;

(10) Rhizoma Gastrodiae: choose decontamination, big or small stepping is soaked in water to pull out slightly thoroughly to seventy percent and dries in the air, and moistens to internal and external temperature evenly again, and section is dried;

(11) Scorpio: remove impurity, cleaning, drying;

(12) Bombyx Batryticatus: choose the silk hair, clean dirt, dry;

(13) Fructus Psoraleae: the clean impurity of winnowing with a dustpan, clean, dry;

(14) Radix Glycyrrhizae: remove impurity, clean, run through, cut sheet, drying;

(15) Olibanum: choose clean Olibanum, put in the pot and see melting point slightly with slow fire to surface, slightly be yellow, taking-up cools, or when frying to surface melting, sprays rice vinegar, continue to fry to layer bright light thoroughly, taking-up cools;

(16) Radix seu herba Heteropogonis Contorti: remove residual stem, clean and dry all herbal medicine;

(17) Radix Angelicae Sinensis: get crude drug, remove impurity, wash quickly is clean, runs through shave, cold drying;

(18) Myrrha: get the Myrrha of choosing clean and put in the pot to fry with slow fire and see melting point slightly to the surface, taking-up cools;

(19) Radix Angelicae Pubescentis: remove impurity, clean, run through, shave dries or cold drying;

(20) Rhizoma Chuanxiong: remove impurity, separately size is slightly steeped, and cleans, and runs through shave, drying;

(21) Radix Gentianae Macrophyllae: choose decontamination, remove removing LU, soak slightly, run through section, dry;

(22) Scolopendra: choose clean, remove cephalopodium, cut off usefulness;

(23) Fructus Chaenomelis: clean, run through or steam shave afterwards, dry;

(24) Radix Notoginseng: choose clean impurity, smash to pieces, grind into powder;

(25) Cortex Eucommiae: remove rough bark, clean, run through, dice or strand dry;

(26) Ramulus Cinnamomi: water soaks slightly, picks up stewing profit to passing through, and section is dried, and sieves anti-dandruff;

(27) Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

3. according to the method for preparing of claim 1 or 2 said medicines, comprise the following steps:

The preparation of honeyed pill:

(1) the crude drug mixing and stirring porphyrize powder after will concocting is crossed 200 order dusting covers;

(2) Mel is refined into 110-115 ℃ tender honey;

(3) will grind for the spice of fine powder by weight 1: 1 ratio add mixed sticking together in the Mel, rubbing pill again, every ball contains pure medicine 1 gram;

(4) in process for preparation in order to prevent that pill from adhering to instrument, smear a small amount of " pill oil ";

(5) preparation of pill oil: add the Cera Flava preparation with vegetable oil, its preparation weight ratio is 4: 1 or 5: 1.

4. according to the method for preparing of claim 1 or 2 said medicines, it is characterized in that: comprise the following steps:

(1) the crude drug mixed together after will concocting stirs, and grinds to be fine powder, crosses 200 order dusting covers, is made as thin medicated powder;

(2) thin medicated powder is incapsulated, every 0.4 restrains or is prepared into tablet or powder.