CN105343442A - External medicament for treating lubar intervertebral disc protrusion and preparation method thereof - Google Patents
External medicament for treating lubar intervertebral disc protrusion and preparation method thereof Download PDFInfo
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- CN105343442A CN105343442A CN201510937676.8A CN201510937676A CN105343442A CN 105343442 A CN105343442 A CN 105343442A CN 201510937676 A CN201510937676 A CN 201510937676A CN 105343442 A CN105343442 A CN 105343442A
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- intervertebral disc
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Abstract
The invention belongs to the field of medicines. An external medicament comprises a fumigating traditional Chinese medicine and an externally-applied traditional Chinese medicine, wherein the fumigating traditional Chinese medicine is prepared from mastic, myrrh, gentiana macrophylla, zaocys dhumnade, long-noded pit viper, aconite root, clematis chinensis, rhizome chuanxiong, phryma leptostachya, rhizoma dioscoreae nipponicae, spina gleditsiae, rubiaceae, radix aconiti kusnezoffii, asarum sieboldii, eupolyphaga and borneol; the externally-applied traditional Chinese medicine is prepared from radix cyathulae, aconite root, drynaria rhizome, pseudo-ginseng, zanthoxylum bungeanum, ginger slice, rhizoma dioscoreae nipponicae, radix angelicae pubescentis, rhizome chuanxiong, radix paeoniae rubra, mastic, myrrh, divaricate saposhnikovia root, flos cartham, dalbergia odorifera, caulis spatholobi, rheum officinale, impatiens balsamina, daemonorops draco, Chinese angelica and borneol. The external medicament disclosed by the invention is scientific in matching, and can be used for quickly dissipating blood stasis to alleviate pain, relieving swelling and dredging channels, and relieving painful spasm caused by the lubar intervertebral disc protrusion due to wind-cold-wetness evil, overstrain and trauma; the fumigating medicine and the externally-applied medicine complement each other, interact and exert respective effects; according to the external medicament, the lubar intervertebral disc protrusion caused by the wind-cold-wetness evil, the overstrain and the trauma is fundamentally cured, and the problems that the lubar intervertebral disc protrusion is difficult to cure and easy to relapse are thoroughly solved.
Description
Technical field
The invention belongs to tcm field, be specifically related to a kind of medicine for external use for the treatment of prolapse of lumbar intervertebral disc and preparation method thereof.
Background technology
Prolapse of lumbar intervertebral disc is also called Annulus Fibrosus of Lumbar Intervertebral Discs and breaks herniation of nucleus pulposus, is one of modal lumbago and skelalgia disease clinically.Sickness rate in crowd is about 15.2%.Its morbidity is mainly because lumbar intervertebral disc each several part, especially vertebral pulp has degenerative change in various degree, under the effect of various external force, the Anular disruption of intervertebral disc, nucleus pulposus is given prominence to from rent, makes adjacent nerve root, and spinal cord and blood vessel etc. are stimulated or oppress, thus produce pain in the lumbar region, sciatica, the symptoms such as side or bilateral lower limb pain, numbness.Lumbar intervertebral disc bears the weight of trunk and upper limb, lumbar vertebra is again the hinge of trunk activity simultaneously, and all body kinematicses are all increasing the load of lumbar vertebra, crowd's intervertebral disc of more than 30 years old is all having regression, and regression comprises the regression of the regression of fibrous ring, the regression of vertebral pulp and cartilage endplate.
The Therapeutic Method of prolapse of lumbar intervertebral disc is a lot, and Chinese and western medicine emphasizes particularly on different fields, and from the practical situation of current clinical treatment prolapse of lumbar intervertebral disc, the traditional Chinese medical science does not advocate operative treatment, and what take is nonoperative conservative treatment.Its main Therapeutic Method has massage whole bone, acupuncture, externally applied ointment, dipping and Chinese medicine for oral administration etc., also has various folk prescriptions among the people, proved recipe.Externally applied ointment, dipping etc. are to relieve muscle spasms, and eliminate muscle inflammation, improving blood circulation has good curative effect, and externally applied ointment is suitable for lumbar vertebra or the slight bruise of muscles and bones.Prolapse of lumbar intervertebral disc can not comprehensively dialectically be treated, also plaster efficacy of a drug impairment after high temperature boils, and skin absorbtivity is few, slow curative effect, can not alleviate rapidly prolapse of lumbar intervertebral disc to having an intense pain of causing of patient and handicapped.But because plaster absorbs slowly, the dipping efficacy of a drug is disperseed, and is difficult to outstanding intervertebral disc the effect reaching treatment.Dialectical Chinese medicine for oral administration can targetedly according to the instant state of an illness of patient from the immunologic function regulating human body constitutionally, regulate the hormonal system of human body, correct the deviation of physiological activity, but due to the obstructed blood vessel of spinal disc interior, Chinese medicine for oral administration is difficult to produce curative effect to outstanding intercalated disc.
The non-operative treatment that western medical treatment prolapse of lumbar intervertebral disc is conventional has oral medicine, intramuscular injection medicine, intravenous drip medicine, block therapy, rumpbone injection treatment, vertebral pulp Thrombosis etc.From present clinical effectiveness, oral or injectable drug is all auxiliary treatment to the treatment of prolapse of lumbar intervertebral disc.Medicine can ease pain, relieve muscle spasms, alleviates the inflammation of muscle and nerve root, but for the position change of intervertebral disk hernia then without obvious curative effects.
Present treatment prolapse of lumbar intervertebral disc, also many medical rehabilitation departments are had to adopt stifling physical therapy, it be with special gassing machine on stifling physical therapy bed or carry out in fumigating bin, its operational approach is that a few herbs prepared are put in small gauze bag, be positioned in the top powder charge box of gassing machine, after water is boiled, steam arrives Chinese medicine bag with flexible pipe, after Chinese medicine bag with flexible pipe enter fumigating bed in or in fumigating bin, local or whole body are carried out to patient and fumigate.Its principle is the active ingredient of being separated out Chinese medicine in Chinese medicine bag by steamed, one be the dose that steams of instant steam very little, two is that the residual part of prescription is little, and the effect acting on affected part is very little, can only play the effect of health-care physical therapy, and without substantial therapeutic effect.
Summary of the invention
Take a broad view of the various therapies of existing Chinese and western medicine Conservative treatments of lumbar disc herniation, they have his own strong points, also respectively deficiency is had, but its general character be a bit not for degenerating, damaged intervertebral disc and relevant ligament, cartilage implement treatment, allow outstanding between the ligament of disk degeneration and cartilage nourished and repaired, make them return to normal, allow intercalated disc revert to the normal portions of vertebral body, in the hope of fundamentally solving the problem of prolapse of lumbar intervertebral disc.Up to now, any report about medicine for external use of the present invention is not also found.The present inventor through repeatedly studying, and passes through the checking repeatedly of clinical trial, finally have found the Chinese medicine external medicine of the treatment prolapse of lumbar intervertebral disc of better curative effect, thus completes the present invention.
Traditional Chinese medicine fumigant active component of the present invention is fumigated prolapse of lumbar intervertebral disc position, allow medicine directly be oozed by the sweat pore at outstanding position and skin with steam under acetic acid ion is led and reach focus, nourish, repair the intercalated disc moving back damage, ligament and cartilage, then the Chinese medicine extract hot compress being aided with strong infiltration, easily absorbing, relaxing muscles and tendons to promote blood circulation, expelling wind and removing dampness, reducing swelling and alleviating pain, economic benefits and social benefits are unified, make the vertebral pulp given prominence to retract within vertebral body, the fibrous ring of degenerating of breaking obtains nourishing, repairing.Make the nerve root no longer pressurized outside epiphysis ring, narrow canalis spinalis is expanded, and reaches the object for the treatment of both the principal and secondary aspects of a disease, thoroughly solves prolapse of lumbar intervertebral disc refractory more, the problem of easily recurrence.And adopt the advantage of medicine for external use of the present invention to be few intercurrent disease, conveniently easily draw, low cost, is suitable for applying.
Chinese medicine external treatment prolapse of lumbar intervertebral disc medicine for external use of the present invention is divided into Traditional Chinese medicine fumigant and takes traditional Chinese medicine outward, and the two complements each other, and relies on for counsel each other.
Traditional Chinese medicine fumigant of the present invention selects Olibanum, Myrrha, Radix Gentianae Macrophyllae, Zaocys, Agkistrodon, Radix Aconiti, Radix Clematidis and Rhizoma Chuanxiong to be monarch drug, be equipped with ministerial drug Herba speranskiae tuberculatae, Rhizoma Dioscoreae Nipponicae, Spina Gleditsiae, Radix Rubiae, Radix Aconiti Kusnezoffii, Herba Asari, Eupolyphaga Seu Steleophaga and Borneolum Syntheticum, Olibanum is wherein selected to be because Olibanum acrid, bitter, warm, for drug for invigorating blood circulation and eliminating stasis, for regulating qi and activating blood, muscles and tendons relaxing to alleviate pain, evacuation of pus is subsided a swelling, and can control all pains of blood stasis.Select Myrrha to be because its property is bitter, pungent, flat, control traumatic injury, incised wound, muscles and bones, all pains of trusted subordinate, lump in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye, join Olibanum, promoting blood circulation to remove blood stasis, circulation of qi promoting relaxing muscles and tendons; Be equipped with Rhizoma Dioscoreae Nipponicae, promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain.Select Radix Gentianae Macrophyllae, because its property is pungent, bitter, be slightly cold, Eradicates rheumatism, relaxing muscles and tendons network, clearind deficient heat, for rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, and infantile malnutrition generates heat.Zaocys, sweet in the mouth, property is put down; Return liver, spleen channel, there is wind-damp dispelling, the meridian dredging, relieving spasm by subduing liver-wind, effect of anti-itch detoxification.Agkistrodon, nature and flavor are sweet, salty, temperature, and return Liver Channel, the main energy of function, dispels the wind, dredging collateral, relieving convulsion; For rheumatoid arthritis stubborn, numbness contracture, middle air port is askew, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.Radix Aconiti, property is pungent, bitter, heat; GUIXIN, liver,kidney,spleen warp, expelling wind and removing dampness, antalgic, the disease such as to have a pain for anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type.Radix Clematidis is selected to be because Radix Clematidis is pungent salty, temperature, poisonous, expelling wind and removing dampness, removing obstruction in the collateral to relieve pain, expectorant water, the loose hypochondriac lump.Rhizoma Chuanxiong, property is pungent, and temperature, returns liver, gallbladder, pericardium channel, blood-activating and qi-promoting, wind-expelling pain-stopping; Pungent loose temperature is led to, and is equipped with the pain relieving of Radix Gentianae Macrophyllae energy dispelling wind and removing obstruction in the collateral, again can dispelling the wind and dampness pathogens arthralgia pain.Herba speranskiae tuberculatae, have another name called and make each efficacy of drugs produce synergism above drug regimen, thus can Efficient software patching green bone, nourish moist, softening reparation degeneration, damaged lumbar intervertebral disc (mainly vertebral pulp and fibrous ring) and relevant ligament and cartilage, life is residual fills a vacancy, expelling wind and removing dampness simultaneously, self-restraint muscles and bones.
In order to reach better curative effect, the present invention removes Traditional Chinese medicine fumigant and also comprises Traditional Chinese Medicine for external application, and described Traditional Chinese Medicine for external application comprises Radix Cyathulae, Radix Aconiti, Rhizoma Drynariae, Radix Notoginseng, Fructus Zanthoxyli, Rhizoma Zingiberis, Rhizoma Dioscoreae Nipponicae, Radix Angelicae Pubescentis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Olibanum, Myrrha, Radix Saposhnikoviae, Flos Carthami, Lignum Dalbergiae Odoriferae, Caulis Spatholobi, Radix Et Rhizoma Rhei, Flos Impatientis, Sanguis Draxonis, Radix Angelicae Sinensis and Borneolum Syntheticum.Wherein in Traditional Chinese Medicine for external application prescription, with Radix Cyathulae, Rhizoma Drynariae, Radix Notoginseng, Fructus Zanthoxyli, Rhizoma Zingiberis, Rhizoma Dioscoreae Nipponicae, Radix Angelicae Pubescentis, Radix Paeoniae Rubra, Flos Carthami, Caulis Spatholobi and when being classified as monarch drug, with Radix Aconiti, Rhizoma Chuanxiong, Olibanum, Myrrha, Radix Saposhnikoviae, Lignum Dalbergiae Odoriferae, Radix Et Rhizoma Rhei, Flos Impatientis, Sanguis Draxonis and Borneolum Syntheticum for ministerial drug, select Radix Cyathulae, due to sweet, the micro-hardship of its property, flat, there is eliminating blood stasis and inducing menstruation, easing joint movement, inducing diuresis for treating stranguria syndrome, for amenorrhea lump in the abdomen, retention of placenta, arthralgia, flaccidity of the lower limbs clonic spasm of the muscle, hematuria stranguria with blood, effect of injury from falling down.Rhizoma Drynariae, property is bitter, temperature, and function cures mainly: the kidney invigorating bone strengthening, continues and hinders pain relieving, for lumbago due to renal deficiency, Hiccough and deaf, odontoseisis, falling winks frustrates, injured bone; External treatment alopecia areata, vitiligo.Radix Notoginseng, sweet in the mouth; Micro-hardship; Warm in nature, flutter congestive edema, thoracic obstruction angor, lump in the abdomen; Blood stasis amenorrhea.Fructus Zanthoxyli, property is pungent, warm, has effect of fragrant stomach invigorating, warming spleen and stomach for dispelling cold, removing damp and stopping pain, parasite killing removing toxic substances, antipruritic solution raw meat.Rhizoma Zingiberis, nature and flavor are pungent, hot, have warming spleen and stomach for dispelling cold, recuperating depleted YANG is promoted blood circulation, warming the lung to resolve fluid-retention effect.Rhizoma Dioscoreae Nipponicae, has another name called Dioscorea nipponica Mak. Ningpo Yam Rhizome, has expelling wind and removing dampness, promoting blood circulation to remove obstruction in the collateral, effect of cough-relieving.Radix Angelicae Pubescentis, property is pungent, bitter, and tepor cures mainly, expelling wind and dampness; Dispersing cold for relieving pain, for anemofrigid-damp arthralgia; Lumbocrural pain; Few cloudy volt wind headache, headache toothache.Radix Paeoniae Rubra, property is bitter, is slightly cold, cures mainly: control the stagnant amenorrhea of the stasis of blood, hernia abdominal mass is gathered, suffer from abdominal pain, hypochondriac pain, epistaxis, dysentery, discharging fresh blood stool, conjunctival congestion, carbuncle, injury from falling down.Flos Carthami, warm in nature, acrid in the mouth, promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, Caulis Spatholobi, property is bitter, sweet, and temperature, enriches blood, invigorate blood circulation, dredging collateral, for menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.Radix Angelicae Sinensis, sweet in the mouth; Pungent; Bitter; Warm in nature, cure mainly: all cards of blood deficiency; Menoxenia; Amenorrhea; Dysmenorrhea; Lump in the abdomen knot is poly-; Metrorrhagia; Asthenia cold abdominalgia; Flaccidity syndrome and arthralgia syndrome; Numbness of the skin; Dryness of the intestine dyschezia; Heavy after bloody dysentery; Ulcer sores; Injury from falling down.Flos Impatientis effect: expelling wind and removing dampness, promoting blood circulation and stopping pain, cures mainly rheumatism disabled wilted limbs etc.Each taste medicine the monarch and his subjects assist a ruler in governing a country above, altogether tool meridians dredging, and expelling wind and cold, relaxing muscles and tendons to promote blood circulation, dissipating blood stasis unstings, the effect of the superfluous blood stasis dispelling that disappears.
The consumption of drug component of the present invention is also through inventor and gropes in a large number to sum up and draw, each amounts of components is all have good therapeutic effect within the scope of following weight parts.
Traditional Chinese medicine fumigant of the present invention, the crude drug primarily of following weight portion is made:
Olibanum: 10 ~ 15 Myrrhas: 8 ~ 15 Radix Gentianae Macrophyllae: 10 ~ 15 Zaocyss: 10 ~ 15
Agkistrodon: 5 ~ 8 Radix Aconitis: 8 ~ 15 Radix Clematidis: 10 ~ 15 Rhizoma Chuanxiongs: 5 ~ 15
Herba speranskiae tuberculatae: 8 ~ 15 Rhizoma Dioscoreae Nipponicae: 5 ~ 15 Spina Gleditsiaes: 5 ~ 15 Radix Rubiaes: 8 ~ 12
Radix Aconiti Kusnezoffii: 5 ~ 10 Herba Asaris: 5 ~ 10 Eupolyphaga Seu Steleophagas: 5 ~ 10 Borneolum Syntheticums: 0.1 ~ 2;
Traditional Chinese Medicine for external application, the crude drug primarily of following weight portion is made:
Radix Cyathulae: 5 ~ 10 Radix Aconitis: 5 ~ 10 Rhizoma Drynariae: 5 ~ 10 Radix Notoginseng: 5 ~ 10
Fructus Zanthoxyli: 5 ~ 15 Rhizoma Zingiberis: 5 ~ 12 Rhizoma Dioscoreae Nipponicae: 5 ~ 10 Radix Angelicae Pubescentiss: 5 ~ 10
Rhizoma Chuanxiong: 5 ~ 10 Radix Paeoniae Rubra: 5 ~ 10 Olibanums: 5 ~ 10 Myrrhas: 5 ~ 10
Radix Saposhnikoviae: 5 ~ 12 Flos Carthamis: 5 ~ 10 Lignum Dalbergiae Odoriferaes: 5 ~ 10 Caulis Spatholobis: 5 ~ 10
Radix Et Rhizoma Rhei: 5 ~ 10 Flos Impatientiss: 5 ~ 12 Sanguis Draxonis 5 ~ 12 Radix Angelicae Sinensis: 5 ~ 12 Borneolum Syntheticums 1 ~ 2.
Preferably, described Traditional Chinese medicine fumigant, comprises the crude drug of following weight portion:
Olibanum: 11.5 ~ 13.5 Myrrhas: 10 ~ 11 Radix Gentianae Macrophyllae 10.5 ~ 12.5 Zaocyss 11.5 ~ 12.5
Agkistrodon: 5.5 ~ 7.5 Radix Aconitis: 9.5 ~ 11.5 Radix Clematidis 11 ~ 12 Rhizoma Chuanxiongs: 9 ~ 10
Herba speranskiae tuberculatae: 8.5 ~ 10.5 Rhizoma Dioscoreae Nipponicae: 8 ~ 10 Spina Gleditsiaes: 8 ~ 10 Radix Rubiaes: 8.5 ~ 9.5
Radix Aconiti Kusnezoffii: 8 ~ 9 Herba Asaris: 7 ~ 9 Eupolyphaga Seu Steleophagas: 6.5 ~ 8.5 Borneolum Syntheticums: 0.5 ~ 1.5.
Preferably, described Traditional Chinese Medicine for external application, comprises the crude drug of following weight portion:
Radix Cyathulae: 6 ~ 8 Radix Aconitis: 5 ~ 7 Rhizoma Drynariae: 6.5 ~ 8.5 Radix Notoginseng: 6 ~ 8
Fructus Zanthoxyli: 9 ~ 11 Rhizoma Zingiberis: 8 ~ 10 Rhizoma Dioscoreae Nipponicae: 6.5 ~ 8.5 Radix Angelicae Pubescentiss: 6 ~ 8
Rhizoma Chuanxiong: 7.5 ~ 9.5 Radix Paeoniae Rubra: 6 ~ 8 Olibanums: 6 ~ 8 Myrrhas: 6 ~ 8
Radix Saposhnikoviae: 8.5 ~ 10.5 Flos Carthamis: 7 ~ 9 Lignum Dalbergiae Odoriferaes: 5 ~ 7 Caulis Spatholobis: 7 ~ 9
Radix Et Rhizoma Rhei: 6 ~ 8 Flos Impatientiss: 6.5 ~ 8.5 Sanguis Draxonis: 6 ~ 8 Radix Angelicae Sinensis: 7 ~ 9 Borneolum Syntheticums: 1 ~ 2.
Described Agkistrodon refers to variously have poisonous snake or nonpoisonous snake, preferably adopts Bungarus Parvus.When preparing Traditional Chinese medicine fumigant active component, internal organs of first Bungarus Parvus being cut open the belly, remove tooth, dry make powder with pulverizer again.
Medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional external preparation.Such as these crude drug can be equipped with adjuvant through the process of preparing Chinese medicine and make patch; Can by these crude drug decocting, then condensed water decocting liquid together except Borneolum Syntheticum, then be mixed and made into painting with Borneolum Syntheticum and put on the skin; But play drug effect better to make each raw material of this medicine; preferably soaking in rice vinegar process is carried out except Borneolum Syntheticum to Traditional Chinese medicine fumigant crude drug and obtain extract; high concentration soaking in Chinese liquor is carried out to external application raw material of Chinese medicine medicine and obtains extract, but these can not be used for limiting the scope of the invention.
Preferably, the preparation method of Traditional Chinese medicine fumigant active component of the present invention is: Olibanum: 10 ~ 15 Myrrhas: 8 ~ 15 Radix Gentianae Macrophyllae: 10 ~ 15 Zaocyss: 10 ~ 15 Agkistrodons: 5 ~ 8 Radix Aconitis: 8 ~ 15 Radix Clematidis: 10 ~ 15 Rhizoma Chuanxiongs: 5 ~ 15 Herba speranskiae tuberculataes: 8 ~ 15 Rhizoma Dioscoreae Nipponicae: 5 ~ 15 Spina Gleditsiaes: 5 ~ 15 Radix Rubiaes: 8 ~ 12 Radix Aconiti Kusnezoffii: 5 ~ 10 Herba Asaris: 5 ~ 10 Eupolyphaga Seu Steleophagas: 5 ~ 10;
Take the crude drug of above-mentioned weight portion, load in container after being broken into fine powder with steel pulverizing, add rice vinegar, seal immersion after uniform stirring 50 ~ 80 days; After the Borneolum Syntheticum of 0.1 ~ 2 weight portion is fully dissolved in Chinese liquor, add in said vesse, leave standstill and filter out medicine residue after 60 ~ 80 days, obtain Traditional Chinese medicine fumigant active component.
Preferably, the preparation method of Traditional Chinese Medicine for external application active component is: Radix Cyathulae: 5 ~ 10 Radix Aconitis: 5 ~ 10 Rhizoma Drynariae: 5 ~ 10 Radix Notoginseng: 5 ~ 10 Fructus Zanthoxylis: 5 ~ 15 Rhizoma Zingiberis: 5 ~ 12 Rhizoma Dioscoreae Nipponicae: 5 ~ 10 Radix Angelicae Pubescentiss: 5 ~ 10 Rhizoma Chuanxiongs: 5 ~ 10 Radix Paeoniae Rubra: 5 ~ 10 Olibanums: 5 ~ 10 Myrrhas: 5 ~ 10 Radix Saposhnikoviaes: 5 ~ 12 Flos Carthamis: 5 ~ 10 Lignum Dalbergiae Odoriferaes: 5 ~ 10 Caulis Spatholobis: 5 ~ 10 Radix Et Rhizoma Rhei: 5 ~ 10 Flos Impatientiss: 5 ~ 12 Sanguis Draxonis 5 ~ 12 Radix Angelicae Sinensis: 5 ~ 12;
Take the crude drug of above weight portion, load in container after being broken into fine powder with steel pulverizing, then add the Borneolum Syntheticum of 1 ~ 2 weight portion, with Chinese liquor sealing immersion 80 ~ 100 days, filter out medicine residue, obtain Traditional Chinese Medicine for external application active component.
In above-mentioned Traditional Chinese medicine fumigant active component preparation method, preferred rice vinegar is 6-9 degree, and the mass ratio of rice vinegar and Traditional Chinese medicine fumigant active component raw material is (15 ~ 27): 1.
Further, described Chinese liquor is 55-65 degree, and the mass volume ratio of Borneolum Syntheticum and Chinese liquor is 1g:(80 ~ 120) ml.
Preferably, the mass ratio of described Chinese liquor and Traditional Chinese Medicine for external application active component raw material is (5 ~ 8): 1.
The active component of medicine of the present invention can add various customary adjuvant required when preparing different dosage form, as lubricant, binding agent etc. are prepared into the conventional exterior-applied formulation of any one as tincture, spirit, powder, lotion, oil preparation, Emulsion, ointment, liniment, gel, aerosol, fumigant, patch etc. with the method for Chinese medicinal of routine.Mix as gained Traditional Chinese Medicine for external application active component is commonly used adjuvant with patch, system is pasted.
The present invention adopts Chinese medicine extract to carry out external application and fumigation treatment of lumbar disc herniation.Is lumbago diseases position comparatively dark, why medicine external application and stiflingly just can reach therapeutic effect outside? Qing Dynasty's physician's Wu Shangxian is said: " reason of external treatment, the i.e. reason for the treatment of by oral administration of medicines; The medicine of external treatment, that is the medicine for the treatment of by oral administration of medicines, different person's method body, medical knowledge, the property of medicine are without two, and the change of rule mystery ... " modern science proves, many medicines can absorb through skin and enter in human body; because absorption process is slow, and action time is longer, sometimes more suitable than oral medicine.Through vein, intramuscular injection and oral medicine, first to be transported to whole body through blood, then work in pathological changes local, consumption is large, and unavoidable side effect is also obvious, the tissue of inner obstructed blood vessel as intervertebral disc, absorb very few especially, and the medicament effective component that external application and position are fumigated is in local absorption, first directly plays a role, and then arrive whole body through blood, therefore, though consumption is little, drug effect also loses little, and side effect is very little, quite safe.
Compared with prior art, the present invention has following beneficial effect:
Traditional Chinese medicine fumigant of the present invention, large prescription compatibility, through soaking in rice vinegar after pulverizing, effective organic component of medicine is all separated out, soak through high spirit, the active ingredient high power of medicine is concentrated to be washed out, uniqueness is imitated in side, then directly aim at prolapse of lumbar intervertebral disc position to fumigate, the various organic components allowing acetic acid ion carry medicine directly ooze with steam and reach focus, nourish moist, the softening vertebral pulp given prominence to and the damaged fibrous ring of degenerating of repairing, ligament and cartilage, allow vertebral pulp, fibrous ring, cartilage and front and back longitudinal ligament recover toughness and elasticity, vertebral pulp absorbs nutrition moisture content and recovers elastic stage, cartilage endplate softens, nourishing Regeneration and Repair, be aided with the conditioning of Traditional Chinese Medicine for external application again, meridians dredging, expelling wind and cold, relaxing muscles and tendons to promote blood circulation, dissipating blood stasis unstings, disappear superfluous blood stasis dispelling, and then inherently cure prolapse of lumbar intervertebral disc.
Medicine for external use of the present invention, prescription is large, dose foot, compatibility science, the large grand unstability suddenly and not of power is appropriate, can unsting by dissipating blood stasis fast, detumescence blood stasis dispelling, alleviates the painful spasm that the prolapse of lumbar intervertebral disc that causes because of wind-cold damp pathogen, strain wound causes, meanwhile, expelling wind and removing dampness, relaxing muscles and tendons to promote blood circulation.Chinese medicine external, without any side effects, avoid the infringement to health and internal organs of injection and oral drugs.Stifling and both liniments complement each other, and act on each other, fumigate as monarch, external application is minister, monarch, each its effect aobvious, fundamentally cure the prolapse of lumbar intervertebral disc caused by wind-cold damp pathogen, wound of straining, thoroughly solve the problem that prolapse of lumbar intervertebral disc refractory more, easily recurs.
Detailed description of the invention
Below by embodiment, the present invention is further elaborated, but is not intended to limit the scope of the invention.If no special instructions, Chinese medicine involved in the present invention all commercially; Herba speranskiae tuberculatae (Latin literary fame: PhrymaleptostachyaL.Subsp.asiatica (Hara) Kitamura has another name called distiller’s yeast grass, Staggergrass etc.) is used as medicine part for rhizome; Flos Impatientis (Classification system Impatiensbalsamina, is commonly called as Flos Impatientis and has another name called buttercup, the herb for Balsaminaceae plant Impatientis) is used as medicine part for dry flower piece; Borneolum Syntheticum refers to natural Broneolum Syntheticum but not synthetic borneol; The Pericarpium Zanthoxyli that Fructus Zanthoxyli and valley produce; If no special instructions, in embodiment, involved method is this area conventional method.Preferably 55 degree of Chinese liquor extract.
Embodiment 1
(1) Traditional Chinese medicine fumigant active component preparation:
Olibanum: 50g Myrrha: 40g Radix Gentianae Macrophyllae: 75g Zaocys: 75g Agkistrodon: 40g
Radix Aconiti: 40g Radix Clematidis: 75g Rhizoma Chuanxiong: 75g Herba speranskiae tuberculatae: 50g Rhizoma Dioscoreae Nipponicae: 50g
Spina Gleditsiae: 25g Radix Rubiae: 40g Radix Aconiti Kusnezoffii: 50g Herba Asari: 45g Eupolyphaga Seu Steleophaga: 50g;
Take the crude drug 780g of above weight, load in container after being broken into fine powder with steel pulverizing, add 24 jin of 6 degree of rice vinegars, seal immersion after uniform stirring 50 days; After the Borneolum Syntheticum of 10g is fully dissolved in 1200ml Chinese liquor, add in said vesse, leave standstill and filter out medicine residue after 60 days, obtain Traditional Chinese medicine fumigant active component.
(2) Traditional Chinese Medicine for external application active component preparation:
Radix Cyathulae: 25g Radix Aconiti: 25g Rhizoma Drynariae: 25g Radix Notoginseng: 25g Fructus Zanthoxyli: 30g
Rhizoma Zingiberis: 30g Rhizoma Dioscoreae Nipponicae: 30g Radix Angelicae Pubescentis: 25g Rhizoma Chuanxiong: 25g Radix Paeoniae Rubra: 30g
Olibanum: 25g Myrrha: 25g Radix Saposhnikoviae: 30g Flos Carthami: 30g Lignum Dalbergiae Odoriferae: 25g
Caulis Spatholobi: 25g Radix Et Rhizoma Rhei: 25g Flos Impatientis: 25g Sanguis Draxonis: 30g Radix Angelicae Sinensis: 30g;
Take the crude drug 540g of above weight, load in container after being broken into fine powder with steel pulverizing, then add 5g Borneolum Syntheticum, with 6 jin of Chinese liquor sealing immersions 80 days, filter out medicine residue, obtain Traditional Chinese Medicine for external application active component.
Embodiment 2
(1) Traditional Chinese medicine fumigant active component preparation:
Olibanum: 75g Myrrha: 75g Radix Gentianae Macrophyllae: 75g Zaocys: 62.5g Agkistrodon: 37.5g
Radix Aconiti: 75g Radix Clematidis: 60g Rhizoma Chuanxiong: 50g Herba speranskiae tuberculatae: 40g Rhizoma Dioscoreae Nipponicae: 25g
Spina Gleditsiae: 40g Radix Rubiae: 50g Radix Aconiti Kusnezoffii: 25g Herba Asari: 35g Eupolyphaga Seu Steleophaga: 25g;
Take the crude drug 750g of above weight, load in container after being broken into fine powder with steel pulverizing, add 25 jin of 9 degree of rice vinegars, seal immersion after uniform stirring 80 days; After 2.5g Borneolum Syntheticum is fully dissolved in 200ml Chinese liquor, add in said vesse, leave standstill and filter out medicine residue after 80 days, obtain Traditional Chinese medicine fumigant active component.
(2) Traditional Chinese Medicine for external application active component preparation:
Radix Cyathulae: 40g Radix Aconiti: 35g Rhizoma Drynariae: 42.5g Radix Notoginseng: 40g Fructus Zanthoxyli: 55g
Rhizoma Zingiberis: 50g Rhizoma Dioscoreae Nipponicae: 42.5g Radix Angelicae Pubescentis: 40g Rhizoma Chuanxiong: 47.5g Radix Paeoniae Rubra: 40g
Olibanum: 40g Myrrha: 40g Radix Saposhnikoviae: 52.5g Flos Carthami: 45g Lignum Dalbergiae Odoriferae: 35g
Caulis Spatholobi: 45g Radix Et Rhizoma Rhei: 40g Flos Impatientis: 42.5g Sanguis Draxonis: 40g Radix Angelicae Sinensis: 45g;
Take the crude drug 857.5g of above weight, load in container after being broken into fine powder with steel pulverizing, then add 5g Borneolum Syntheticum, with 10 jin of Chinese liquor sealing immersions 100 days, filter out medicine residue, obtain Traditional Chinese Medicine for external application active component.
Embodiment 3
(1) Traditional Chinese medicine fumigant active component preparation:
Olibanum: 67.5g Myrrha: 50g Radix Gentianae Macrophyllae: 50g Zaocys: 50g Agkistrodon: 25g
Radix Aconiti: 57.5g Radix Clematidis: 50g Rhizoma Chuanxiong: 25g Herba speranskiae tuberculatae: 42.5g Rhizoma Dioscoreae Nipponicae: 75g
Spina Gleditsiae: 50g Radix Rubiae: 45g Radix Aconiti Kusnezoffii: 40g Herba Asari: 40g Eupolyphaga Seu Steleophaga: 40g;
Take the crude drug 707.5g of above weight, load in container after being broken into fine powder with steel pulverizing, add 35 jin of 9 degree of rice vinegars, seal immersion after uniform stirring 80 days; After 7.5g Borneolum Syntheticum is fully dissolved in 900ml Chinese liquor, add in said vesse, leave standstill and filter out medicine residue after 80 days, obtain Traditional Chinese medicine fumigant active component.
(2) Traditional Chinese Medicine for external application active component preparation:
Radix Cyathulae: 30g Radix Aconiti: 25g Rhizoma Drynariae: 32.5g Radix Notoginseng: 30g Fructus Zanthoxyli: 45g
Rhizoma Zingiberis: 40g Rhizoma Dioscoreae Nipponicae: 32.5g Radix Angelicae Pubescentis: 30g Rhizoma Chuanxiong: 37.5g Radix Paeoniae Rubra: 30g
Olibanum: 30g Myrrha: 30g Radix Saposhnikoviae: 42.5g Flos Carthami: 35g Lignum Dalbergiae Odoriferae: 25g
Caulis Spatholobi: 35g Radix Et Rhizoma Rhei: 30g Flos Impatientis: 32.5g Sanguis Draxonis: 30g Radix Angelicae Sinensis: 35g;
Take the crude drug 657.5g of above weight, load in container after being broken into fine powder with steel pulverizing, then add the Borneolum Syntheticum of 7.5g, with 9 jin of Chinese liquor sealing immersions 100 days, filter out medicine residue, obtain Traditional Chinese Medicine for external application active component.
Embodiment 4
(1) Traditional Chinese medicine fumigant active component preparation:
Olibanum: 60g Myrrha: 55g Radix Gentianae Macrophyllae: 60g Zaocys: 60g Agkistrodon: 30g
Radix Aconiti: 50g Radix Clematidis: 55g Rhizoma Chuanxiong: 45g Herba speranskiae tuberculatae: 50g Rhizoma Dioscoreae Nipponicae: 40g
Spina Gleditsiae: 40g Radix Rubiae: 42.5g Radix Aconiti Kusnezoffii: 45g Herba Asari: 40g Eupolyphaga Seu Steleophaga: 32.5g;
Take the crude drug 705g of above weight portion, load in container after being broken into fine powder with steel pulverizing, add 23 jin of 9 degree of rice vinegars, seal immersion after uniform stirring 70 days; After 10g Borneolum Syntheticum is fully dissolved in 800ml Chinese liquor, add in said vesse, leave standstill and filter out medicine residue after 70 days, obtain Traditional Chinese medicine fumigant active component.
(2) Traditional Chinese Medicine for external application active component preparation:
Radix Cyathulae: 50g Radix Aconiti: 50g Rhizoma Drynariae: 50g Radix Notoginseng: 50g Fructus Zanthoxyli: 75g Rhizoma Zingiberis: 25g Rhizoma Dioscoreae Nipponicae: 25g Radix Angelicae Pubescentis: 50g Rhizoma Chuanxiong: 50g Radix Paeoniae Rubra: 25g Olibanum: 50g Myrrha: 30g Radix Saposhnikoviae: 25g Flos Carthami: 25g Lignum Dalbergiae Odoriferae: 25g Caulis Spatholobi: 50g Radix Et Rhizoma Rhei: 50g Flos Impatientis: 60g Sanguis Draxonis: 25g Radix Angelicae Sinensis: 25g;
Take the crude drug 815g of above weight portion, load in container after being broken into fine powder with steel pulverizing, then add the Borneolum Syntheticum of 10g, with 9 liters of Chinese liquor sealing immersions 90 days, filter out medicine residue, obtain Traditional Chinese Medicine for external application active component.
Embodiment 5
(1) Traditional Chinese medicine fumigant active component preparation:
Olibanum: 67.5g Myrrha: 55g Radix Gentianae Macrophyllae: 62.5g Zaocys: 62.5g Agkistrodon: 37.5g
Radix Aconiti: 57.5g Radix Clematidis: 60g Rhizoma Chuanxiong: 50g Herba speranskiae tuberculatae: 52.5g Rhizoma Dioscoreae Nipponicae: 50g
Spina Gleditsiae: 50g Radix Rubiae: 47.5g Radix Aconiti Kusnezoffii: 45g Herba Asari: 45g Eupolyphaga Seu Steleophaga: 42.5g;
Take the crude drug 785g of above weight portion, load in container after being broken into fine powder with steel pulverizing, add 40 jin of rice vinegars, seal immersion after uniform stirring 70 days; After 7g Borneolum Syntheticum is fully dissolved in 800ml Chinese liquor, add in said vesse, leave standstill and filter out medicine residue after 70 days, obtain Traditional Chinese medicine fumigant active component.
(3) Traditional Chinese Medicine for external application active component preparation:
Radix Cyathulae: 30g Radix Aconiti: 25g Rhizoma Drynariae: 32.5g Radix Notoginseng: 30g Fructus Zanthoxyli: 45g
Rhizoma Zingiberis: 40g Rhizoma Dioscoreae Nipponicae: 32.5g Radix Angelicae Pubescentis: 30g Rhizoma Chuanxiong: 37.5g Radix Paeoniae Rubra: 30g
Olibanum: 30g Myrrha: 30g Radix Saposhnikoviae: 42.5g Flos Carthami: 35g Lignum Dalbergiae Odoriferae: 25g
Caulis Spatholobi: 35g Radix Et Rhizoma Rhei: 30g Flos Impatientis: 32.5g Sanguis Draxonis: 42.5g Radix Angelicae Sinensis: 35g;
Take the crude drug 670g of above weight portion, load in container after being broken into fine powder with steel pulverizing, then add 10g Borneolum Syntheticum, with 9 jin of Chinese liquor sealing immersions 90 days, filter out medicine residue, obtain Traditional Chinese Medicine for external application active component.
Test example
Medicine for external use of the present invention is adopted to carry out clinical trial to patient
1, medication
Concrete operations: outsourcing or make by oneself fumigating bed, patient is lain low on fumigating bed, rumpbone exposes entirely with upper lumbar spine, the rustless steel grill pan of a bore at 16 ~ 18cm is put at the lower corresponding lumbar vertebra position of bed, pour in pot by Traditional Chinese medicine fumigant active component, each consumption about 250ml, pot applies the towel folded, from medicinal liquid boiled emerge steam time timing, 30 minutes.Every other day fumigate once, the residual liquid smoked is outwelled and is not re-used.Traditional Chinese Medicine for external application active component is made patch, and namely each needle tubing extracts about 10ml medicinal liquid, sprays evenly on plaster, then plaster is affixed on affected part, within 6 ~ 8 hours, can takes off.Traditional Chinese medicine fumigant and Traditional Chinese Medicine for external application are handed over and are used.
2, observation index
Have dull pain during patient's waist, strong down to foot pain on sciatic nerve place or leg, aobvious with feeling of numbness, gently then difficulty in walking, waist of bowing, sit up difficulty, heavy then be unable to leave the bed.
3, therapeutic effect criterion
Transference cure, without lumbago and skelalgia, picotement etc., normally can walk, waist of bowing, to sit up.
Test example 1
Jiang: female, 51 years old
Cardinal symptom: have dull pain during waist, right sciatic nerves place and right lower limb are keenly felt strongly down to foot, aobvious with feeling of numbness, difficulty in walking, and once at Daliang City's hospital admission, hospital's suggestion must operative treatment.
CT Findings: waist L4/5 intervertebral disc exceeds vertebral rim soft-tissue density's shadow symmetrically as seen, dural sac leading edge pressurized, swell on the right side of L5/S1 intervertebral disc visible limitation soft-tissue density image canalis spinalis, right neuron root pressurized, L5/S1 intervertebral space is narrow as seen, and L3-5 vertebral rim is shown in that irregular hyperosteogeny changes.
Diagnostic imaging: L4/5 annuler bulge, L5/S1 intervertebral disk hernia.L5/S1 spinal canal stenosis, L3-5 vertebral body hyperosteogeny.
Start to adopt medicine for external use of the present invention to carry out physical therapy in June, 2011, the lumbago and skelalgia after 8 times that hockets, picotement disappear substantially (physical therapy number of times by stifling number of times, following case all with).Be almost recovered after 12 times, do not recur so far.
Test example 2
Xu certain: man, 36 years old
Cardinal symptom: flank pain, left lower limb severe pain from top to down, numb, be unable to leave the bed, find waist before first quarter moon and the pain that has a pain in the leg, go to see a doctor, per os take medicine and plaster invalid after attempt again massaging, traction, aggravation of keenly feeling after three times, bed is unable to stir any more.
CT Findings: L4/5 intercalated disc to the even bulging of surrounding, dural sac pressurized, L5/S1 intercalated disc Central protrusion, both sides root compression.
Diagnostic imaging: L4/5 annuler bulge, L5/s1 intervertebral disk hernia.
Physical therapy from August, 2011, every day gives his external application Chinese medicine, can get up and be careful, after connecting again deposited three days medicines, can walk, start to fumigate after the 9th day after six days.Symptom resolution after 8 times, is almost recovered, and does not recur so far.
Test example 3
Liu: man, 49 years old
Cardinal symptom: flank pain, pain picotement is strong from top to down for right lower limb, difficulty in walking.
CT Findings: swell on the right side of waist L4/5 intervertebral disc visible limitation soft-tissue density image canalis spinalis, right neuron root pressurized, intervertebral foramina is narrow as seen.L3-5 vertebral body sees lip sample hypertrophy.
Diagnostic imaging: L4/5 intervertebral disk hernia, spinal canal stenosis, L3-5 hyperosteogeny.
In physical therapy in January, 2012, carry out after stifling and external application replaces physical therapy 9 times to lumbar vertebra, leg fiber crops pain disappears, but lumbar vertebra still time have hypodynia sense, be almost recovered after 13 times, do not recur so far.
Test example 4
Grandson: man, 49 years old
Cardinal symptom: it is violent that right lower limb aches sense from sciatic nerve to toe, and shank and foot numbness, bed can not be walked, and this symptom operationally causes.
CT Findings: waist L4/5 intercalated disc is outstanding to right lateral side, pressuring neural root.
Diagnostic imaging: lumbar vertebra L4/5 intercalated disc is given prominence to.
Start physical therapy in August, 2012, Traditional Chinese Medicine for external application 4 pastes, and pain alleviates, and can walk, and second day starts to carry out stifling and external application to lumbar vertebra protuberance.After 8 times, symptom greatly takes a turn for the better, and 10 recoveries from illness, do not recur so far.Test example 5
In certain: man, 45 years old
Cardinal symptom: flank pain, have pain, picotement when both sides sciatic nerve and thigh, waist of bowing, sit up difficulty.
CT Findings, waist L4/5L5/S1 intervertebral disc exceeds vertebral rim soft-tissue density's shadow symmetrically all as seen, dural sac leading edge pressurized, hypertrophy that L3-5 vertebral rim is slight.
Diagnostic imaging: L4/5L5/S1 annuler bulge, L3-5 hyperosteogeny.
Start physical therapy in December, 2012, the external application of Chinese medicine and stifling carried out to lumbar vertebra position, 6 times afterwards pain picotement start to alleviate, to 13 recoveries from illness, do not recur so far.
Test example 6
Pueraria lobota: man, 48 years old
Cardinal symptom: pain on the right side of waist, right sciatic nerves and skelalgia sense are strong, have the sense of weightlessness, difficulty in walking, suffer from this disease more than 20 day during right lower limb, once eat oral medicine and externally applied plaster is invalid.
CT Findings: waist L3/4 intervertebral disc is evenly to surrounding bulging, and dural sac pressurized, L4/5L5/S1 canalis spinalis gap narrows as seen.
Diagnostic imaging: L3/4 annuler bulge, L4/5, L5/S1 intervertebral disk hernia, spinal canal stenosis.
Start physical therapy in June, 2014, to lumbar vertebra, stifling and external application hockets, and after 7 times, symptom is alleviated to some extent, fully recovers, do not recur so far after 20 times.
Test example 7
Finish certain: man, 48 years old
Cardinal symptom: waist is ached, right sciatic nerves and right lower limb hurt like hell sometimes up and down, sit up difficulty especially.
CT Findings: waist L3/4L4/5 intervertebral disc evenly bulging backward, picture pressurized before dural sac, L5/S1 intervertebral disc central authorities type to the right is given prominence to, root compression, picture lip sample hypertrophy before L4/5 vertebral body.L5 vertebral body is slight retrolisthesis.
Diagnostic imaging: L3/4L4/5 annuler bulge, L5/S1 intervertebral disk hernia, L4-5 hyperosteogeny, L5 vertebral body retrolisthesis.
Start physical therapy in January, 2015, carry out stifling and external application to lumbar vertebra, after 8 times, symptom starts to take a turn for the better, and 17 recoveries from illness, do not recur so far.
The above; be only the present invention's preferably detailed description of the invention; but protection scope of the present invention is not limited thereto; anyly be familiar with those skilled in the art in the technical scope that the present invention discloses; be equal to according to technical scheme of the present invention and inventive concept thereof and replace or change, all should be encompassed within protection scope of the present invention.
Claims (9)
1. treat a medicine for external use for prolapse of lumbar intervertebral disc, it is characterized in that, comprise Traditional Chinese medicine fumigant and Traditional Chinese Medicine for external application, described Traditional Chinese medicine fumigant, the crude drug primarily of following weight portion is made:
Described Traditional Chinese Medicine for external application, the crude drug primarily of following weight portion is made:
2. a kind of medicine for external use for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that described Traditional Chinese medicine fumigant comprises the crude drug of following weight portion:
3. a kind of medicine for external use for the treatment of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that described Traditional Chinese Medicine for external application comprises the crude drug of following weight portion:
4. a kind of preparation method for the treatment of the medicine for external use of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that, the preparation method of Traditional Chinese medicine fumigant active component is:
Take the crude drug of above-mentioned weight portion, load in container after being broken into fine powder with steel pulverizing, add rice vinegar, seal immersion after uniform stirring 50 ~ 80 days; After the Borneolum Syntheticum of 0.1 ~ 2 weight portion is fully dissolved in Chinese liquor, add in said vesse, leave standstill and filter out medicine residue after 60 ~ 80 days, obtain Traditional Chinese medicine fumigant active component.
5. a kind of preparation method for the treatment of the medicine for external use of prolapse of lumbar intervertebral disc according to claim 1, is characterized in that, the preparation method of Traditional Chinese Medicine for external application active component is:
Take the crude drug of above weight portion, load in container after being broken into fine powder with steel pulverizing, then add the Borneolum Syntheticum of 1 ~ 2 weight portion, with Chinese liquor sealing immersion 80 ~ 100 days, filter out medicine residue, obtain Traditional Chinese Medicine for external application active component.
6. a kind of preparation method for the treatment of the medicine for external use of prolapse of lumbar intervertebral disc according to claim 4, is characterized in that, described rice vinegar is 6-9 degree, and the mass ratio of rice vinegar and Traditional Chinese medicine fumigant active component raw material is (15 ~ 27): 1.
7. a kind of preparation method for the treatment of the medicine for external use of prolapse of lumbar intervertebral disc according to claim 4, is characterized in that, described Chinese liquor is 55-65 degree, and the mass volume ratio of Borneolum Syntheticum and Chinese liquor is 1g:(80 ~ 120) ml.
8. a kind of preparation method for the treatment of the medicine for external use of prolapse of lumbar intervertebral disc according to claim 5, is characterized in that, the mass ratio of described Chinese liquor and Traditional Chinese Medicine for external application active component raw material is (5 ~ 8): 1.
9. a kind of preparation method for the treatment of the medicine for external use of prolapse of lumbar intervertebral disc according to claim 5, is characterized in that, gained Traditional Chinese Medicine for external application active component is commonly used adjuvant with patch and mixes, and system is pasted.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510937676.8A CN105343442A (en) | 2015-12-15 | 2015-12-15 | External medicament for treating lubar intervertebral disc protrusion and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510937676.8A CN105343442A (en) | 2015-12-15 | 2015-12-15 | External medicament for treating lubar intervertebral disc protrusion and preparation method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109010563A (en) * | 2018-10-08 | 2018-12-18 | 安徽牧春堂天然药物研究开发有限公司 | It is a kind of for treating the traditional Chinese medicine plaster and preparation method thereof of lumbar vertebra disease, cervical spondylosis |
| CN111529667A (en) * | 2020-06-11 | 2020-08-14 | 浙江一真堂健康管理有限公司 | Traditional Chinese medicine composition for treating lumbar intervertebral disc protrusion and application |
| CN114832085A (en) * | 2022-04-27 | 2022-08-02 | 来友谊 | Traditional Chinese medicine composition for treating lumbar disc herniation and application thereof, traditional Chinese medicine hot compress bag and preparation method thereof |
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| CN1315200A (en) * | 2000-03-31 | 2001-10-03 | 朱大岩 | Exterior-applied medicine for treating lumbar intervertebral disk protrusion |
| CN101549028A (en) * | 2008-03-31 | 2009-10-07 | 靳会军 | Son-mother hot compressing fumigation chamber therapy |
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| CN1315200A (en) * | 2000-03-31 | 2001-10-03 | 朱大岩 | Exterior-applied medicine for treating lumbar intervertebral disk protrusion |
| CN101549028A (en) * | 2008-03-31 | 2009-10-07 | 靳会军 | Son-mother hot compressing fumigation chamber therapy |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109010563A (en) * | 2018-10-08 | 2018-12-18 | 安徽牧春堂天然药物研究开发有限公司 | It is a kind of for treating the traditional Chinese medicine plaster and preparation method thereof of lumbar vertebra disease, cervical spondylosis |
| CN111529667A (en) * | 2020-06-11 | 2020-08-14 | 浙江一真堂健康管理有限公司 | Traditional Chinese medicine composition for treating lumbar intervertebral disc protrusion and application |
| CN114832085A (en) * | 2022-04-27 | 2022-08-02 | 来友谊 | Traditional Chinese medicine composition for treating lumbar disc herniation and application thereof, traditional Chinese medicine hot compress bag and preparation method thereof |
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Application publication date: 20160224 |