CN105664029A

CN105664029A - Plaster for treating cervical muscle type cervical spondylosis

Info

Publication number: CN105664029A
Application number: CN201610095612.2A
Authority: CN
Inventors: 不公告发明人
Original assignee: Individual
Current assignee: Individual
Priority date: 2014-04-28
Filing date: 2014-04-28
Publication date: 2016-06-15

Abstract

The invention discloses a plaster for treating cervical muscle type cervical spondylosis. The plaster is mainly prepared from, by weight, 10-18 parts of bombardier beetle, 1-10 parts of pawpaw, 10-17 parts of red-rooted salvia root, 5-10 parts of notopterygium root, 3-10 parts of radix curcumae longae, 9-13 parts of krait, 6-15 parts of herba pyrolae, 3-10 parts of radix clematidis, 5-10 parts of veratrum japonicum and 5-9 parts of rhizoma dioscoreae nipponicae. The plaster can activate blood to promote menstruation, relieve pain and dredge collaterals and has a good treatment effect on cervical spondylosis and complications thereof.

Description

A kind of plaster treating cervical muscle myelopathy

Divisional application, original applying number 2014101736883, applying date 2014.04.28, a kind of plaster treating cervical muscle myelopathy of title and preparation method thereof.

Technical field

The invention discloses a kind of plaster treating cervical muscle myelopathy and preparation method thereof, its dosage form is unguentum, the invention belongs to traditional Chinese medicine field.

Background technology

Cervical spondylosis, also known as cervical spine syndrome, is the general name of osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion, is a kind of illness changing into basis with degeneration pathology. Strain for a long time mainly due to cervical vertebra, hyperosteogeny, or prolapse of intervertebral disc, ligament thicken, and causes cervical vertebra spinal cord, nerve root or vertebral artery pressurized, a series of handicapped clinical syndrome occurs. Show as intervertebral disc degradation itself and insecondary a series of pathological change thereof, as vertebra saves unstability, loosens; Nucleus pulposus or deviate from; Bony spur is formed; The plump spinal canal stenosis etc. with secondary of ligament, stimulates or has oppressed the tissues such as the nerve root of vicinity, spinal cord, vertebral artery and cervical region sympathetic nerve, causing series of symptoms and sign.

The clinical symptoms of cervical spondylosis is complex. Mainly have nape pain, upper myasthenia of limbs, finger is numb, lower limb are weak, difficulty in walking, dizziness, Nausea and vomiting, even blurred vision, tachycardia and dysphagia etc. The clinical symptoms of cervical spondylosis has certain relation with diseased region, tissue involved and individual variation.

The inspection method of cervical spondylosis includes following several.

1, the test inspection of cervical spondylosis and physical examination, including: rotation neck test that (1) is anteflexion. Make that patient's cervical region is anteflexion, advise its rotary moveable to the left and right. As pain occurs in cervical vertebra place, it was shown that cervical facet joint has degeneration; (2) intervertebral foramina squeeze test (test of bearing down on one). Make patient's head deflection Ipsilateral, examiner's left hand palm is put in patient's head, the right hand the is clenched fist tapping left hand back of the body, then occur that limbs radiating pain or numbness, expression strength pass down to intervertebral foramina and diminishes, have root to damage; To root pain severity person, examiner's with the hands overlap be put in the crown, under pressurization, can bring out or aggravate symptom. When patients head be in neutral position or after stretch time to occur that the applied voltage test positive is referred to as Jackson head test positive; (3) brachial plexus distraction test. Patient bows, the hand steered patient's incidence of examiner one, another hold suffering limb wrist, do rightabout push-and-pull, see whether patient feels radiating pain or numbness, this is called that Eaten tests. As tractive forces suffering limb to make pronation more simultaneously, then it is called that Eaten strengthens test; (4) test is stretched after upper limb. Examiner be placed on the other hand healthy side shoulder portion rise fixation, another hold in patient's wrist, and make its gradually backward, outward in stretch-like, to increase cervical nerve root tractive, if radiating pain occurs in suffering limb, it was shown that cervical nerve root or brachial plexus have pressurized or damage. 2, x-ray inspection.The male of normal more than 40 years old, the women of more than 45 years old there are about 90% bony spur that there is cervical vertebral body. Therefore have the change of x-ray plain film, it is not necessary to there is clinical symptoms. Now relevant with cervical spondylosis x-ray finding is described below: (1) normotopia. Observe with or without pivot ring joint dislocation, odontoid fracture or disappearance. C7 transverse process is with or without long, with or without cervical rib. Uncovertebral joint and intervertebral space are with or without broadening or narrow; (2) position, side. 1. the change of curvature. Cervical vertebra is sent out directly, physiology prolapse disappears or contraflexure; 2. abnormal movement degree. Cross at cervical vertebra and extend through in the X-ray film of position, side in the wrong, it is possible to the elasticity seeing intervertebral disc changes; 3. hyperosteogeny. All can produce hyperosteogeny and ligament calcification close to the position of intervertebral disc before and after vertebral body; 4. narrowing of intervertebral space. Intervertebral disc can because of Nucleus pulposus, and intervertebral disc water content reduces and fibre modification occurs and thinning, shows on X-ray film as narrowing of intervertebral space. 5. subluxation and intervertebral foramina diminish. After degeneration of intervertebral disc, interpyramidal poor stability, vertebral body tends to occur subluxation, or is referred to as sliding vertebra; 6. ligamentum nuchae ossification. Ligamentum nuchae ossification is one of typical cytopathic of cervical spondylosis; (3) loxosis. Take the photograph vertebra left and right oblique film, be mainly used to the situation observing the size of intervertebral foramina and uncovertebral joint hyperosteogeny. 3, electromyography. The electromyography of cervical spondylosis and prolapse of cervical intervertebral disc all can point out nerve root long-term pressurized that degeneration occurs, thus losing the inhibitory action to arranged muscle. 4, CT examination. CT has been used for the caused canalis spinalis such as diagnosis ossification of posterior longitudinal ligament, spinal canal stenosis, tumor of spinal cord and expands or bone destruction, measures bone density to estimate osteoporotic degree. Additionally, due to cross fault image can clearly see the soft tissue inside and outside dural sheath and subarachnoid space. Therefore can correctly diagnose the empty disease of intervertebral disc prolapse, neurofibroma, spinal cord or oblongata, diagnosis and Differential Diagnosis for cervical spondylosis have certain value.

If cervical spondylosis is treated not in time, causing the appearance of complication for a long time, complication of cervical spondylopathy disease mainly has following several.

1, dysphagia. There are in sense of obstruction, esophagus to have foreign body sensation, a few peoples to have Nausea and vomiting, hoarseness, dry cough, the symptom such as uncomfortable in chest when swallowing. This is directly to oppress esophagus rear wall due to cervical vertebra leading edge and cause esophagostenosis, it is also possible to make esophagus surrounding soft tissue occur caused by irritant reaction because bony spur is formed to overrun. 2, visual disorder. Show as visual deterioration, ophthalmic bloated pain, keep in dark place, shed tears, pupil size not etc., even occur that constriction of visual field and vision fall sharply, few patients also can occur blind. This causes autonomic nervous dysfunction and vertebral-basilar artery insufficiency with cervical spondylosis and the brain occipital lobe visual centre ischemic disease damage that causes is relevant. 3, neck heart syndrome. Show as precordialgia, uncomfortable in chest, arrhythmia (such as premature beat etc.) and ECG ST section to change, be easily misdiagnosed as coronary heart disease. This is that nape nerve root is subject to caused by stimulation and the compressing of cervical osteophytes. 4, hypertension cervical spondylosis. Can cause elevation of the blood pressure or reduce, wherein with blood pressure rising for many, be called " neck hypertension ". Owing to cervical spondylosis and hypertension are all the commonly encountered diseases of middle-aged and elderly people, therefore both usually and deposit. 5, chest pain. Show as onset obstinate unilateral pectoralis major and mastalgia slowly, during inspection, have pectoralis major tenderness. This is relevant by cervical osteophytes compressing with neck 6 and C7nerve root.6, lower extremity paralysis. Early manifestation is numbness of lower limbs, pain, limping, some patients when walking just like the sensation stepping on Cotton Gossypii, few patients also can with defecation, dysuria, such as frequent micturition, urgent micturition, urinate smooth or gatism etc. This is because vertebral body lateral bundle is subject to stimulation or the compressing of cervical osteophytes, cause caused by lower extremity movement and sensory disturbance. 7, damping off. It is everlasting when standing or walk and occurs that health loses holding power and dampings off because turning one's head suddenly, can quickly regain consciousness after falling down to the ground, without disturbance of consciousness, also no sequel. This type of patient can with the symptom of the autonomic nervous dysfunctions such as dizziness, Nausea and vomiting, perspiration. This is to cause basilar arterial blood supply obstacle owing to hyperosteogeny sexually revises compressing vertebral artery, causes caused by momentary cerebral blood supply insufficiency.

In the invention of existing treatment cervical muscle myelopathy, Authorization Notice No. CN102406789B(application number 201110393441.9) Chinese patent disclose a kind of plaster treating cervical spondylosis: Radix Angelicae Sinensis 30 grams, Radix Salviae Miltiorrhizae 40 grams, Herba Aristolochiae Mollissimae 35 grams, Formica fusca 35 grams, Semen Sinapis Albae 40 grams, Radix Achyranthis Bidentatae 30 grams, Fructus Foeniculi 35 grams, Radix Aconiti Kusnezoffii 20 grams, Rhizoma Chuanxiong 30 grams, Scolopendra 20 grams, Scorpio 30 grams, Semen Strychni 30 grams, Sanguis Draxonis 30 grams, Myrrha 40 grams, Olibanum 30 grams, Borneolum Syntheticum 30 grams, preparation method: take Radix Angelicae Sinensis 30 grams, Radix Salviae Miltiorrhizae 40 grams, Herba Aristolochiae Mollissimae 35 grams, Formica fusca 35 grams, Semen Sinapis Albae 40 grams, Radix Achyranthis Bidentatae 30 grams, Fructus Foeniculi 35 grams, Radix Aconiti Kusnezoffii 20 grams, Rhizoma Chuanxiong 30 grams, Scolopendra 20 grams, Scorpio 30 grams, Semen Strychni 30 grams, add the water of 5 times of said medicine weight, slow fire boiling is dragged for slag after 60 minutes and is made decoction, Sanguis Draxonis 30 grams is added in decoction, Myrrha 40 grams, Olibanum 30 grams, Borneolum Syntheticum 30 grams, after slow fire heating is extremely agent dissolving, add Plumbum preparatium and make ointment, cream of getting it filled uniformly is applied on the cloth of stand and makes plaster, every 10 gram of one patch, if life-time service is easily generated drug resistance. application publication number CN103230447A(application number 201310115163.X) Chinese patent disclose a kind of external medicine wine treating cervical spondylosis, formula and part by weight are Semen Strychni 10 parts, Pheropsophus jessoensis Mor. 20 parts, Radix Aconiti 12 parts, Radix Aconiti Kusnezoffii 10 parts, Radix Clematidis 20 parts, Hirudo 15 parts, Bungarus fasciatus 15 parts, Caulis Spatholobi 25 parts, Borneolum Syntheticum 6 parts, above-mentioned raw materials medicine is weighed in proportion and assorts, with pharmaceutical equipment apparatus concoct qualified, purify, concentration adjusts in 1:100 ratio with 75% ethanol or 600 Chinese liquor after making fine powder that to convert into medicated wine standby, after smearing, volatilization is very fast, it is impossible to continuingly act on affected part.

Summary of the invention

For existing current treatment status, an object of the present invention is in that to provide a kind of plaster treating cervical muscle myelopathy, not only has blood circulation promoting and blood stasis dispelling, the effect of inducing menstruation to relieve menalgia, also having administration time lasting for a long time, active constituent content is high, and local efficacy is the feature such as definite substantially.

The preparation method that another object of the present invention is just to provide the plaster of above-mentioned treatment cervical muscle myelopathy.

The above-mentioned purpose of the present invention is achieved through the following technical solutions:

A kind of plaster treating cervical muscle myelopathy, take off the primary raw material stating weight proportion to be prepared from: Pheropsophus jessoensis Mor. 10-18 part, Fructus Chaenomelis 1-10 part, Radix Salviae Miltiorrhizae 10-17 part, Rhizoma Et Radix Notopterygii 5-10 part, Rhizoma Curcumae Longae 3-10 part, Bungarus fasciatus 9-13 part, Herba Pyrolae 6-15 part, Radix Clematidis 3-10 part, seven lis of red 5-10 parts, Rhizoma Dioscoreae Nipponicae 5-9 part.

The plaster of above-mentioned treatment cervical muscle myelopathy, preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 13-16 part, Fructus Chaenomelis 3-7 part, Radix Salviae Miltiorrhizae 13-15 part, Rhizoma Et Radix Notopterygii 7-9 part, Rhizoma Curcumae Longae 5-8 part, Bungarus fasciatus 10-12 part, Herba Pyrolae 10-12 part, Radix Clematidis 5-8 part, seven lis of red 6-9 parts, Rhizoma Dioscoreae Nipponicae 6-8 part.

The plaster of the above treatment cervical muscle myelopathy, more preferably preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 15 parts, Fructus Chaenomelis 5 parts, Radix Salviae Miltiorrhizae 14 parts, Rhizoma Et Radix Notopterygii 8 parts, 6 parts of Rhizoma Curcumae Longae, Bungarus fasciatus 11 parts, Herba Pyrolae 11 parts, Radix Clematidis 7 parts, seven lis of pellets 8 parts, Rhizoma Dioscoreae Nipponicae 7 parts.

Preparation method according to the above plaster of arbitrary described treatment cervical muscle myelopathy, step is as follows:

1. being placed in non iron container by Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and stands 10-20 days, filters, obtains filtrate and filtering residue is standby;

2. being added water by step 1. middle gained filtering residue, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolaes, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 20-40 minute, filters to get filtrate;

3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 5-10 hour, filter, filtrate purifies again by the way of distillation, obtains distillate standby;

4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C-80 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 5-15g to spread upon in adhesive plaster or other substrate, make plaster.

According to above-mentioned preparation method, it is preferred that scheme is in that: 1. step stands 13-18 days (preferably 15 days).

According to above-mentioned preparation method, it is preferred that scheme is in that: 2. step decocts to 25-35 minute (preferably 30 minutes).

According to above-mentioned preparation method, it is preferred that scheme is in that: 3. step stands 7-9 hour (preferably 8 hours).

According to above-mentioned preparation method, it is preferred that scheme is in that: step 4. 65 DEG C-75 DEG C (preferably 70 DEG C).

According to above-mentioned preparation method, it is preferred that scheme is in that: the weight ratio of step 4. vegetable oil, Colophonium, white vaseline and distillate is 1:1.5:1.5:1.

The application when the medicine of cervical spondylotic myelopathy, spondylotic radiculopathy cervical muscle myelopathy is treated in preparation of the plaster of the treatment cervical muscle myelopathy according to any of the above item.

Best using method: for the therapeutic effect making the present invention reach the best, plaster is directly affixed on uncomfortable cervical vertebra place, gently seals about 1 minute with palm after patch, and patch is worn 12 hours, and every day 1 time, 10 days is a course for the treatment of.

A kind of plaster treating cervical muscle myelopathy, the pharmacological effect of each raw material is respectively as follows:

Pheropsophus jessoensis Mor.: base: walk cape for Carabidae and belong to the Scorpio of animal tiger spot cloth cape. The property of medicine: pungent, temperature. Function cures mainly: blood circulation promoting and blood stasis dispelling, removing obstruction for relieving pain. Cure mainly amenorrhea due to stagnation of blood, dysmenorrhea, puerperal the stagnant stomachache of the stasis of blood, lump in the abdomen, traumatic injury stasis of blood pain.

Fructus Chaenomelis: sour in the mouth, warm in nature. Return liver, spleen channel. Effect: suppressing the hyperactive liver relaxing muscles and tendons, stomach function regulating removing dampness. Cure mainly: arthralgia chiefly caused by damp pathogen contracture, waist knee joint acid weight pain, convulsion of vomiting and diarrhoea, beriberi edema.

Radix Salviae Miltiorrhizae: bitter in the mouth, cold nature. GUIXIN, Liver Channel. Effect: stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, clear away heart-fire relieving restlessness. Curing mainly: menoxenia, amenorrhea dysmenorrhea, abdominal mass is gathered, chest and abdomen twinge, pyretic arthralgia pain, and skin infection swells and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.

Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature. Return bladder, kidney channel. Effect: cold expelling, dispels the wind, dehumidifying, pain relieving. Cure mainly: anemofrigid cold is had a headache, rheumatic arthralgia, aching pain in shoulder and back.

Rhizoma Curcumae Longae: acrid in the mouth, hardship, warm in nature.Return liver, spleen channel. Effect: removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia. Cure mainly: amenorrhea due to stagnation of blood, menalgia, breast side of body twinge, rheumatic arthralgia, take on arm pain, injury from falling down.

Bungarus fasciatus: base: remove the entirety of internal organs for Elapidae Bungarus animal Bungarus fasciatus. Composition: meat is containing protein, aminoacid, fat and 21 kinds of trace element such as ferrum, aluminum, pungent, strontium, titanium, manganese, copper, barium. Containing pseudocholinesterase in serum. Another containing echidnotoxin and peptide: blue bungarotoxin, Bungarus fasciatus toxin A, B etc. The property of medicine: " Guangxi Chinese medicinal herbal ": " salty in the mouth, warm in nature. Enter Liver Channel. " function cures mainly: dispel the wind, dehumidifying, dredging collateral, pain relieving. Cure mainly rheumatoid arthritis stubborn, numb limbs and tense tendons, contraction urgency pain, paralysis due to windstroke, hemiplegia. Compatibility and incompatibility of drugs: " Guangxi Chinese medicinal herbal ": " numbness as belonged to the dry muscle of blood withered avoids use. " Herba Pyrolae: sweet in the mouth, hardship, warm in nature. Return liver, kidney channel. Effect: wind-damp dispelling, bone and muscle strengthening, hemostasis. Cure mainly: rheumatic arthralgia, weakness of the waist and knees, menorrhagia, chronic cough due to asthenia of viscera.

Radix Clematidis: acrid in the mouth, salty, warm in nature. Return bladder warp. Effect: expelling wind and removing dampness, removing obstruction in the collateral to relieve pain. Curing mainly: rheumatic arthralgia. numb limbs and tense tendons, muscle arteries and veins contracture, joint stuffiness, bone chokes down larynx.

Seven lis of pellets: base: for rhizome and the root of the black purple Rhizoma et radix veratri (Radix Rhizoma Veratri) of Liliaceae Veratrum. The property of medicine: " a collection of selected materials of Guangxi book on Chinese herbal medicine ": " bitter in the mouth is pungent, cold in nature, very toxic. " function cures mainly: gush expectorant, dissipating blood stasis, pain relieving, parasite killing, eliminating stasis to stop pain. Cure mainly apoplexy, demented accumulation and obstruction of sputum, traumatic injury, malignant boil, scabies. Compatibility and incompatibility of drugs: " Fujian medicine will ": " be not taken by pregnant women. Can not with all ginsengs, Herba Asari, Radix Paeoniae compatibility. " Rhizoma Dioscoreae Nipponicae: salty in the mouth, cold nature. Return liver, stomach warp. Effect: stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, searches wind and removing obstruction in channels. Cure mainly: amenorrhea abdominal mass, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture.

Rhizoma Dioscoreae Nipponicae: return liver, kidney, lung meridian, warm in nature, sweet in the mouth, hardship. Relaxing muscles and tendons to promote blood circulation, relieving cough and resolving phlegm, wind-expelling pain-stopping. For lumbago and skelalgia, rheumatalgia, rheumatic arthritis, muscles and bones numbness, Kaschin-Beck disease, traumatic injury, sprain one's back, cough pant, tracheitis, bronchitis.

Colophonium, vegetable oil, white vaseline are excipient, play the effect of mediation figuration. Plaster, is the big dosage form-ball of Chinese medicine five, scattered, one of cream, pellet, soup. Ancient doctor's speech is said: " plaster can be cured the disease, not different from decoction, does in the proper way with it, and it rings vertical answering. " prescription of the present invention all selects pungent perfume (or spice) to walk to go here and there extremely strong tying-in medicine, medicine directly infiltrates through skin, by interior transmission from one channel to another network, plays disperse blood stasis and dredge collateral, the effect that pain relieving is stimulated the menstrual flow.

Detailed description of the invention

Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.

Embodiment 1 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 10 parts, Fructus Chaenomelis 1 part, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Et Radix Notopterygii 5 parts, 3 parts of Rhizoma Curcumae Longae, Bungarus fasciatus 9 parts, Herba Pyrolae 6 parts, Radix Clematidis 3 parts, seven lis of pellets 5 parts, Rhizoma Dioscoreae Nipponicae 5 parts.

The preparation method of the plaster of above-mentioned treatment cervical muscle myelopathy, step is:

1. being placed in non iron container by Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae, add ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and stands 10 days, filters, obtains filtrate and filtering residue is standby;

2. being added water by step 1. middle gained filtering residue, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolaes, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 20 minutes, filters to get filtrate;

3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 5 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby;

4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 5g to spread upon in adhesive plaster or other substrate, make plaster.

Typical case one king XX, man, 55 years old, people from Qingzhou, Weifang City, workman. Long-term in factory work, cervical muscle myelopathy history 1 year, cervicodynia is uncomfortable in chest, and with the symptom of blurred vision, nearest right arm sensation grips unable, and health has constrained sense, couches night and all feels uncomfortable, it is impossible to falls asleep and cause lethargy. Checking and find patient's instability of gait, hands grasping power is all not high, and right arm situation is even more serious, and compression of spinal cord is comparatively obvious, seeks medical advice everywhere, all to no effect, it is not intended on newspaper, see plaster of the present invention, have the attitude tried in arms and bought 2 courses for the treatment of.

Using the embodiment of the present invention 1 gained plaster, once a day, patch is worn 12 hours every time, and cervical region and right arm scapular region respectively paste one, within 10 days, are a course for the treatment of. Using 10 days, nighttime sleep has clear improvement, it is possible to sleeping. Using 20 days, both hands have obvious strength high, and mental attitude is taken on a new look to some extent, and pain symptom alleviates. Using 30 days, pain substantially alleviates, and mental restoration is good, and vision is also recovered to some extent. Using 50 days, other malaise symptoms disappear substantially, and patient's self-induction is fully recovered.

Embodiment 2 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 18 parts, Fructus Chaenomelis 10 parts, Radix Salviae Miltiorrhizae 17 parts, Rhizoma Et Radix Notopterygii 10 parts, 10 parts of Rhizoma Curcumae Longae, Bungarus fasciatus 13 parts, Herba Pyrolae 15 parts, Radix Clematidis 10 parts, seven lis of pellets 10 parts, Rhizoma Dioscoreae Nipponicae 9 parts.

1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, adding ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and stands 20 days, filter, obtain filtrate and filtering residue is standby;

2. being added water by step 1. middle gained filtering residue, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolaes, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 40 minutes, filters to get filtrate;

3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 10 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby;

4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 80 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 15g to spread upon in adhesive plaster or other substrate, make plaster.

Embodiment 3 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 13 parts, Fructus Chaenomelis 3 parts, Radix Salviae Miltiorrhizae 13 parts, Rhizoma Et Radix Notopterygii 7 parts, 5 parts of Rhizoma Curcumae Longae, Bungarus fasciatus 10 parts, Herba Pyrolae 10 parts, Radix Clematidis 5 parts, seven lis of pellets 6 parts, Rhizoma Dioscoreae Nipponicae 6 parts.

1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, adding ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and stands 13 days, filter, obtain filtrate and filtering residue is standby;

2. being added water by step 1. middle gained filtering residue, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolaes, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 25 minutes, filters to get filtrate;

3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 7 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby;

4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 65 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 8g to spread upon in adhesive plaster or other substrate, make plaster.

Typical case two field XX, female, 35 years old, Weifang, Shandong personage, the office worker of certain foreign enterprise. long-term facing to computer work, one day almost little motion, it is nearly all facing to computer, during last summer, conscious left side neck root, shoulder and left upper arm pain, and extremity have slight feeling of numbness, originally do not take notice of, but before 1 month, there is urgent micturition in patient, frequent micturition, the symptom of constipation, household sees that the aggravation of its disease just goes to hospital to check, check and find patient's Wry Neck, cervical region is tilted to the right limited, when cervical region rotates to the left, the pain increased, cervical region all has obvious tenderness sense with doing scapula position, the X sheet display slight lateral bending of cervical flexure, it is diagnosed as: cervical muscle myelopathy, doctor is it have been suggested that use embodiment 3 gained plaster.

Using the embodiment of the present invention 3 gained plaster, once a day, patch is worn 12 hours every time, and cervical region and scapular region respectively paste one, within 10 days, are a course for the treatment of. Using 5 days, patch wears position the sensation of heating, feels well. Using 20 days, pain alleviates. Using 30 days, when noting posture and rest, substantially can avoid the generation of cervical pain symptom, omoplate place pain is wholly absent, and cervical region can comparatively swing normally, and defecation is normal, and have no side effect during use generation.

Embodiment 4 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 16 parts, Fructus Chaenomelis 7 parts, Radix Salviae Miltiorrhizae 15 parts, Rhizoma Et Radix Notopterygii 9 parts, 8 parts of Rhizoma Curcumae Longae, Bungarus fasciatus 12 parts, Herba Pyrolae 12 parts, Radix Clematidis 8 parts, seven lis of pellets 9 parts, Rhizoma Dioscoreae Nipponicae 8 parts.

1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, adding ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and stands 18 days, filter, obtain filtrate and filtering residue is standby;

2. being added water by step 1. middle gained filtering residue, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolaes, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 35 minutes, filters to get filtrate;

3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 9 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby;

4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 75 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 13g to spread upon in adhesive plaster or other substrate, make plaster.

Typical case three grandson XX, man, 40 years old, Jinan, people from Shandong personage, the workman of certain factory. Before 1 half a year, sensation neck descendants rises suddenly, and right side numbness of lower limbs, pain, thinks it is that work is tired out at the beginning, does not also take notice of very much, but occur in that both upper extremities is numb in the time of nearest half a year, and neck aches is severe. Patient's fearing very at that time, checks to Jinan large hospital under the accompanying of layman, checks and finds patient's restriction of neck motion, the pain increased in layback, cervical region tenderness is obvious, is diagnosed as: cervical muscle myelopathy, begins to use the embodiment of the present invention 4 gained plaster under the suggestion of doctor.

Using the embodiment of the present invention 4 gained plaster, once a day, patch wears 12 hours in cervical pain place every time, within 10 days, is a course for the treatment of. Using 10 days, pain is substantially alleviated, and numb limbs and tense tendons sense makes moderate progress. Using 20 days, pain disappears substantially, and feeling of numbness is substantially alleviated, and has strength on foot. Being continuing with 10 days, patient's self-induction is fully recovered.

Embodiment 5 one kinds treats the plaster of cervical muscle myelopathy, takes off the primary raw material stating weight proportion and is prepared from: Pheropsophus jessoensis Mor. 15 parts, Fructus Chaenomelis 5 parts, Radix Salviae Miltiorrhizae 14 parts, Rhizoma Et Radix Notopterygii 8 parts, 6 parts of Rhizoma Curcumae Longae, Bungarus fasciatus 11 parts, Herba Pyrolae 11 parts, Radix Clematidis 7 parts, seven lis of pellets 8 parts, Rhizoma Dioscoreae Nipponicae 7 parts.

1. Pheropsophus jessoensis Mor., Fructus Chaenomelis, Radix Salviae Miltiorrhizae, Rhizoma Et Radix Notopterygii, Rhizoma Curcumae Longae, Bungarus fasciatus, Herba Pyrolae, Radix Clematidis, Rhizoma Dioscoreae Nipponicae are placed in non iron container, adding ethanol, the consumption of ethanol is 2 times of the total consumption of crude drug, and sealing is placed in shady and cool ventilation place and stands 15 days, filter, obtain filtrate and filtering residue is standby;

2. being added water by step 1. middle gained filtering residue, the consumption of water is 4 times of filtering residue consumption, and adds seven lis of pellets, Bungarus fasciatus, Herba Pyrolaes, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 30 minutes, filters to get filtrate;

3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 8 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby;

4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 70 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 10g to spread upon in adhesive plaster or other substrate, make plaster.

Experimental example, in order to verify the present invention curative effect to cervical muscle myelopathy, has chosen two or more person 100 people of cervical muscle myelopathy symptom, and the mean age is 40 years old, it is divided into two groups according to the state of an illness, experimental group and matched group, often organize 50 people, basically identical to ensure two groups of situations. Experimental group uses embodiment 5 gained plaster, once a day, patch wears 12 hours every time, it within 10 days, it is a course for the treatment of, matched group uses the Chinese medicine of other oral medication cervical muscle myelopathys, observes 30 days time limits, and before experiment, first 1 day symptom to patient comprehensively checks, regularly check inquiry patient body situation and impression during experiment, and make a record.

1, the curative effect of two groups of medicines being recorded, result is table 1 below such as. (criterion, effectively: the malaise symptoms caused by cervical muscle myelopathy has clear improvement; Invalid: the malaise symptoms caused by cervical muscle myelopathy is unchanged. )

Table 1:

Analyze: as can be seen from Table 1, the effective percentage of cervical muscle myelopathy is 99% by the present invention, exceeds matched group 11%, and effect is notable.

2, two groups of patient's applied mental changes being recorded, result is table 2 below such as.

Table 2:

Analyze: as can be seen from Table 2, medicament mode of the present invention is easier to be approved by patient, and major part represents per capita, Long-term taking medicine easily causes mental pressure, and appetite can be significantly affected, external used medicine is favored by more people on therapeutic modality, also more easily accepts and adheres to long-term treatment. Through to the analyses organizing experimental datas more it can be seen that plaster of the present invention is obvious for cervical muscle myelopathy curative effect, total effective rate is up to 96%, and without any side effects, it is possible to reach the effect of pain-alleviating and network vessel-freeing comparatively rapidly. On therapeutic modality, the present invention is also easier to by patient's recognition and acceptance, it is possible to lay a good foundation for later treatment.

Claims

1. treat a plaster for cervical muscle myelopathy, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Pheropsophus jessoensis Mor. 10 parts, Fructus Chaenomelis 1 part, Radix Salviae Miltiorrhizae 10 parts, Rhizoma Et Radix Notopterygii 5 parts, 3 parts of Rhizoma Curcumae Longae, Bungarus fasciatus 9 parts, Herba Pyrolae 6 parts, Radix Clematidis 3 parts, seven lis of pellets 5 parts, Rhizoma Dioscoreae Nipponicae 5 parts.

2. the preparation method treating the plaster of cervical muscle myelopathy, is characterized in that,