CN104116936A - Plaster for treating cervical spondylosis and lumbar spondylosis - Google Patents

Plaster for treating cervical spondylosis and lumbar spondylosis Download PDF

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CN104116936A
CN104116936A CN201410399201.3A CN201410399201A CN104116936A CN 104116936 A CN104116936 A CN 104116936A CN 201410399201 A CN201410399201 A CN 201410399201A CN 104116936 A CN104116936 A CN 104116936A
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parts
plaster
radix
internal layer
rhizoma
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陶海峰
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Abstract

The invention discloses a plaster for treating cervical spondylosis and lumbar spondylosis and belongs to the technical field of plaster preparations. The plaster comprises a vector (1), an outer plaster (2) and an inner plaster (3), wherein the inner plaster (3) is arranged between the outer plaster (2) and the vector (1); the coating area of the outer plaster (2) is greater than that of the inner plaster (3); a coating region of an inner plaster body is positioned inside a plaster coating region of the outer plaster (2). The plaster can be used for effectively treating spondylodynia, repairing connective tissue and nerve tissue damages caused by spondylodynia and relieving spinal disease complications, and the plaster is low in allergic rate and does not mould and lose the pharmacological effect after being stored for a long period of time. According to the preparation method of the plaster, the plaster is purified by adopting an oil-soaking extraction mode or an ethyl alcohol and water mixed liquor extraction mode, and the obtained outer plaster can have the effects of preventing corrosion, inhibiting bacteria, resisting allergy and preventing the inner plaster from being aired and crushed.

Description

A kind of plaster for the treatment of cervical spondylosis lumbar spondylosis
Technical field
Treat a plaster for cervical spondylosis lumbar spondylosis, belong to plaster processing technique field.
Background technology
Spondylopathy is exactly sclerotin, intervertebral disc, ligament, the muscle generation pathological changes of vertebra, thereby and then compressing, traction stimulate spinal cord, spinal nerves, blood vessel, vegetative nerve to occur complicated and diversified symptom.Commonly encountered diseases kind is cervical spondylosis, lumbar spondylosis.Cardinal symptom: can not be uprightly, headache, dizzy, blurred vision, hypomnesis, neck shoulder ache, inappetence, regurgitation, vomiting, weakness of the lower extremities, severe patient may cause paralysis.Cervical spondylosis claims again cervical spine syndrome, is the general name of osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion, is a kind ofly to change into basic illness with degeneration pathology.Mainly due to cervical vertebra strain for a long time, hyperosteogeny, or prolapse of intervertebral disc, ligament thicken, and causes cervical vertebra spinal cord, nerve root or vertebral artery pressurized, occurs a series of handicapped clinical syndromes.Show as intervertebral disc degradation itself and insecondary a series of pathological change thereof, as vertebra joint unstability, loosening; Vertebral pulp is given prominence to or is deviate from; Bony spur forms; The spinal canal stenosis of ligament plumpness and secondary etc., stimulate or have oppressed the tissues such as contiguous nerve root, spinal cord, vertebral artery and cervical region sympathetic nerve, cause series of symptoms and sign.
Cervical spondylosis is mainly divided into following several: cervical spondylopathy is the cervical spondylosis of earliest period, also claim local myelopathy, there is pain and the corresponding pressure pain point of head, shoulder, neck, arm, on X-ray film, there is no the obvious degenerative changes such as stenosis of disc space, but can there is the change of cervical vertebrae physiological curve, the variation such as unstable and slight hyperosteogeny between vertebral body.Many patients of stiff neck repeatedly belong to this kind of change.When cervical region stretches naturally, physiological camber weakens or disappears, and somebody's cervical region is partially askew, and movable normal or slightly limited, musculi colli spasm, is dispersed in pressure pain point.Sympathetic type of cervical spondylosis: due to intervertebral disc degeneration and the factor such as segmental is unstable, thereby cervical vertebra SNE is around caused to stimulation, produce sympathetic nerve function disorder.
Sympathetic type of cervical spondylosis symptom is various, and majority shows as sympathetic activation symptom, and minority is that sympathetic nerve suppresses symptom.Because vertebral artery rich surface is containing sympathetic fiber, in the time that sympathetic nerve function is disorderly, usually involve vertebral artery, cause vertebrarterial systolic and diastolic function abnormal.Therefore in sympathetic cervical spondylosis in there are the multiple systemic symptoms of whole body, also usually with the performance of Vertebro-basilar System blood supply insufficiency.
Cervical spondylotic radiculopathy: due to one-sided or bilateral spinal nerve root irriate or pressurized, it shows as the sensation consistent with spinal nerve root areal area, motion and reflecting barrier, primary disease is more common, various non-operative treatment targetedly all have obvious curative effect, wherein especially continue with head and neck or are interrupted traction, neck circumference braking and correct bad position effective.Prognosis is mostly better.
Cervical spondylotic myelopathy: be because the regression of cervical vertebral body degeneration and adjacent soft tissue has caused the direct compressing to spinal cord, add the impact of the dynamic factors such as violent motion or long-term faulty posture, cause compression of spinal cord or ischemia of spinal cord, then occur the dysfunction of spinal cord.
Esophagus compressive cervical spondylosis: esophagus compressive cervical spondylosis claims again dysphagia myelopathy, mainly due to intervertebral disc degeneration secondary anterior longitudinal ligament and subperiosteum tear, due to hemorrhage, machine calcification and bony spur forms.
Vertebral artery type of cervical spondylosis: and get involved and can cause the symptomes complices such as dizzy blurred vision because cervical region sympathetic nerve is subject to excitation to cause vertebral artery, be referred to as vertebral artery type of cervical spondylosis, vertebral artery compression syndrome, cervical vertigo, vertebral artery ischemic syndrome, vertebra one basilar artery insufficiency etc.Vertebral artery type of cervical spondylosis is slightly common than cervical spondylotic myelopathy, because large polyphyly is wherein due to due to vertebra joint shakiness.
Although there is the design that uses plaster treatment spondylopathy in prior art, but there is following shortcoming in existing plaster treatment: first, the plaster of existing treatment spondylopathy can only respite pain, but the connective tissue causing for spondylopathy and neural tissue injury can not well treat, cause the treatment of spondylopathy to be difficult to recovery from illness.Secondly, directly and contact skin, while causing patient to use easily there is anaphylaxis in skin to existing black plaster moderate stimulation composition, and even red and swollen, diabrosis phenomenon appear in docile face; And the treatment of the plaster docile of spondylopathy is a long-term process, the high anaphylaxis of existing plaster causes patient to be often impatient at and in advance plaster is taken off, until plaster cannot reach therapeutic effect; Particularly the docile time of black plaster mostly is more than 3 days, the high zest of plaster also easily cause patient cannot be in sleep docile plaster and being taken off before having to fall asleep at night, therapeutic effect is caused to harmful effect; Again, in existing plaster, there is volatile active ingredient and be difficult to long-time preservation, though exist and plaster monolithic be kept to design in packaging bag but this design still cannot stop the disengaging of volatilizing from plaster of the volatile ingredient of the onset in plaster, often cause black plaster drug effect constantly to reduce along with punishing severely of resting period, when the actual docile plaster of patient, therapeutic effect is undesirable.
Summary of the invention
The technical problem to be solved in the present invention is: overcome the deficiencies in the prior art, a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis is provided, this plaster, this plaster can effectively be treated spondylopathy, repair the connective tissue that causes of spondylopathy and neural tissue injury, alleviation spondylopathy complication, and low, the long-time storage of the irritated rate of this plaster is not gone mouldy and is not lost drug effect.
The technical solution adopted for the present invention to solve the technical problems is: the plaster of this treatment cervical spondylosis lumbar spondylosis, a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis, it is characterized in that: comprise successively from top to bottom outer plaster, internal layer plaster and carrier, the coated area of outer plaster is greater than the coated area of internal layer plaster;
Internal layer plaster is made up of the dry raw material of following weight portion: 5 ~ 10 parts of Os Draconis (calcined)s, 5 ~ 10 parts of Pheretimas, 5 ~ 10 parts of Scolopendras, 5 ~ 10 parts of Scorpios, 5 ~ 10 parts of Hirudos, 5 ~ 10 parts of Bombyx Batryticatus, shell 10 ~ 15 parts of Limaxs, 5 ~ 10 parts of Cordyceps, 5 ~ 10 parts of Olibanums, 5 ~ 10 parts of Myrrhas, 5 ~ 10 parts of Endoconcha Sepiaes, 1 ~ 3 part of Borneolum Syntheticum, 2 ~ 5 parts of Colophonium, 2 ~ 5 parts of succinums, 15 ~ 25 parts of Caulis Spatholobis, 10 ~ 20 parts of Caulis Polygoni Multiflori, 20 ~ 30 parts of Caulis Loniceraes, 10 ~ 20 parts of Radix Aconiti Preparatas, 10 ~ 20 parts of Herba Asaris, 10 ~ 20 parts of Radix Dipsacis, 10 ~ 20 parts of the Cortexs Eucommiae, 10 ~ 20 parts of Radix Aconiti Lateralis Preparatas, 10 ~ 20 parts of Flos Magnoliaes, 10 ~ 20 parts of Radix cocculi laurifoliis, 10 ~ 20 parts of Radix Angelicae Pubescentiss, 10 ~ 20 parts of Herba Rosmarini Officinaliss, 10 ~ 20 parts of Ramulus Sambuci Williamsii, 5 ~ 10 parts of Benzoinumes, 5 ~ 10 parts of Sanguis Draxonis, 10 ~ 20 parts of Radix Angelicae Sinensis, 10 ~ 20 parts of Cortex Cinnamomis, 5 ~ 10 parts, Fructus Capsici, 10 ~ 20 parts of Herba Pelargonii Graveolentiss, 20 ~ 30 parts of Coriolous Dersicolor (Fr.) Quel, 40 ~ 50 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 20 ~ 30 parts of Grifola frondosa, 40 ~ 50 parts of Radix Scutellariaes, 40 ~ 50 parts of Radix Et Rhizoma Rhei, 40 ~ 50 parts of the Radixs Angelicae Dahuricae, 40 ~ 50 parts of Geckos, 20 ~ 30 parts, Semen Persicae, 40 ~ 50 parts of Semen Ziziphi Spinosaes, 20 ~ 30 parts of Fructus Caricae, 20 ~ 30 parts, Fructus Pruni pseudocerasi, 20 ~ 30 parts of Fructus Hippophaes, 30 ~ 40 parts of Semen Aesculies, 20 ~ 30 parts of the Radixs Astragali, 20 ~ 30 parts of Folium Ginkgos, 40 ~ 50 parts of Galla Chinensiss, 20 ~ 30 parts of Radix Rhodiolaes, 20 ~ 30 parts of Stigma Crocis, 20 ~ 30 parts of Cortex Moutans, 20 ~ 30 parts, Rhizoma Gastrodiae, 20 ~ 30 parts of Rhizoma Polygoni Cuspidati, 20 ~ 30 parts of Rhizoma Belamcandae, 20 ~ 30 parts of Radix Bupleuri, 30 ~ 40 parts of Radix orixae japonicaes, 20 ~ 30 parts of Flos Albiziaes, 20 ~ 30 parts of Flos Rosae Chinensiss, 20 ~ 30 parts of Herb Gynostemmae Pentaphylli, 20 ~ 30 parts of Radix gynurae segeti, 20 ~ 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 ~ 15 parts of Radix Scrophulariaes, 10 ~ 15 parts of Radix Sophorae Flavescentiss, 30 ~ 40 parts of Cortex Phellodendris, 500 ~ 1000 parts of Plumbum preparatiums, 1000 ~ 2000 parts of Oleum sesami,
Outer plaster is made up of the dry raw material of following weight portion: 0.5 ~ 2 part of glycyrrhizic acid dipotassium, 1 ~ 5 part of trehalose, 1 ~ 10 part, Folium olive, 1 ~ 10 part, Cera Flava, 1 ~ 10 part of squalane, 1 ~ 5 part of dimethyl sulfone.
Preferably, internal layer plaster is made up of the dry raw material of following weight portion: 7 ~ 9 parts of Os Draconis (calcined)s, 7 ~ 9 parts of Pheretimas, 7 ~ 9 parts of Scolopendras, 7 ~ 9 parts of Scorpios, 7 ~ 9 parts of Hirudos, 7 ~ 9 parts of Bombyx Batryticatus, shell 12 ~ 14 parts of Limaxs, 7 ~ 9 parts of Cordyceps, 7 ~ 9 parts of Olibanums, 7 ~ 9 parts of Myrrhas, 7 ~ 9 parts of Endoconcha Sepiaes, 1 ~ 3 part of Borneolum Syntheticum, 2 ~ 5 parts of Colophonium, 2 ~ 5 parts of succinums, 15 ~ 25 parts of Caulis Spatholobis, 13 ~ 17 parts of Caulis Polygoni Multiflori, 22 ~ 26 parts of Caulis Loniceraes, 13 ~ 17 parts of Radix Aconiti Preparatas, 13 ~ 17 parts of Herba Asaris, 13 ~ 17 parts of Radix Dipsacis, 13 ~ 17 parts of the Cortexs Eucommiae, 13 ~ 17 parts of Radix Aconiti Lateralis Preparatas, 13 ~ 17 parts of Flos Magnoliaes, 13 ~ 17 parts of Radix cocculi laurifoliis, 13 ~ 17 parts of Radix Angelicae Pubescentiss, 13 ~ 17 parts of Herba Rosmarini Officinaliss, 13 ~ 17 parts of Ramulus Sambuci Williamsii, 7 ~ 9 parts of Benzoinumes, 7 ~ 9 parts of Sanguis Draxonis, 13 ~ 17 parts of Radix Angelicae Sinensis, 13 ~ 17 parts of Cortex Cinnamomis, 7 ~ 9 parts, Fructus Capsici, 13 ~ 17 parts of Herba Pelargonii Graveolentiss, 22 ~ 26 parts of Coriolous Dersicolor (Fr.) Quel, 45 ~ 48 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 22 ~ 26 parts of Grifola frondosa, 45 ~ 48 parts of Radix Scutellariaes, 45 ~ 48 parts of Radix Et Rhizoma Rhei, 45 ~ 48 parts of the Radixs Angelicae Dahuricae, 45 ~ 48 parts of Geckos, 22 ~ 26 parts, Semen Persicae, 45 ~ 48 parts of Semen Ziziphi Spinosaes, 22 ~ 26 parts of Fructus Caricae, 22 ~ 26 parts, Fructus Pruni pseudocerasi, 22 ~ 26 parts of Fructus Hippophaes, 35 ~ 38 parts of Semen Aesculies, 22 ~ 26 parts of the Radixs Astragali, 22 ~ 26 parts of Folium Ginkgos, 45 ~ 48 parts of Galla Chinensiss, 22 ~ 26 parts of Radix Rhodiolaes, 22 ~ 26 parts of Stigma Crocis, 22 ~ 26 parts of Cortex Moutans, 22 ~ 26 parts, Rhizoma Gastrodiae, 22 ~ 26 parts of Rhizoma Polygoni Cuspidati, 22 ~ 26 parts of Rhizoma Belamcandae, 22 ~ 26 parts of Radix Bupleuri, 35 ~ 38 parts of Radix orixae japonicaes, 22 ~ 26 parts of Flos Albiziaes, 22 ~ 26 parts of Flos Rosae Chinensiss, 22 ~ 26 parts of Herb Gynostemmae Pentaphylli, 22 ~ 26 parts of Radix gynurae segeti, 22 ~ 26 parts of the Rhizoma Atractylodis Macrocephalaes, 12 ~ 14 parts of Radix Scrophulariaes, 12 ~ 14 parts of Radix Sophorae Flavescentiss, 35 ~ 38 parts of Cortex Phellodendris, 500 ~ 1000 parts of Plumbum preparatiums, 1000 ~ 2000 parts of Oleum sesami,
Preferably, outer plaster is made up of the dry raw material of following weight portion: 0.7 ~ 1.5 part of glycyrrhizic acid dipotassium, 2 ~ 4 parts of trehaloses, 2 ~ 6 parts, Folium olive, 4 ~ 9 parts, Cera Flava, 2 ~ 7 parts of squalanes, 2 ~ 4 parts of dimethyl sulfones.
Preferably, described internal layer plaster is made up of the dry raw material of following weight portion: 7 parts of Os Draconis (calcined)s, 8 parts of Pheretimas, 7 parts of Scolopendras, 7 parts of Scorpios, 8 parts of Hirudos, 9 parts of Bombyx Batryticatus, shell 13 parts of Limaxs, 9 parts of Cordyceps, 8 parts of Olibanums, 7 parts of Myrrhas, 8 parts of Endoconcha Sepiaes, 1.5 parts of Borneolum Syntheticums, 2 parts of Colophonium, 3 parts of succinums, 18 parts of Caulis Spatholobis, 14 parts of Caulis Polygoni Multiflori, 23 parts of Caulis Loniceraes, 15 parts of Radix Aconiti Preparatas, 16 parts of Herba Asaris, 14 parts of Radix Dipsacis, 14 parts of the Cortexs Eucommiae, 15 parts of Radix Aconiti Lateralis Preparatas, 14 parts of Flos Magnoliaes, 16 parts of Radix cocculi laurifoliis, 14 parts of Radix Angelicae Pubescentiss, 17 parts of Herba Rosmarini Officinaliss, 14 parts of Ramulus Sambuci Williamsii, 7 parts of Benzoinumes, 7 parts of Sanguis Draxonis, 16 parts of Radix Angelicae Sinensis, 14 parts of Cortex Cinnamomis, 7 parts, Fructus Capsici, 16 parts of Herba Pelargonii Graveolentiss, 23 parts of Coriolous Dersicolor (Fr.) Quel, 47 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 25 parts of Grifola frondosa, 47 parts of Radix Scutellariaes, 45 parts of Radix Et Rhizoma Rhei, 45 parts of the Radixs Angelicae Dahuricae, 45 parts of Geckos, 23 parts, Semen Persicae, 487 parts of Semen Ziziphi Spinosaes, 23 parts of Fructus Caricae, 25 parts, Fructus Pruni pseudocerasi, 25 parts of Fructus Hippophaes, 37 parts of Semen Aesculies, 24 parts of the Radixs Astragali, 24 parts of Folium Ginkgos, 45 parts of Galla Chinensiss, 25 parts of Radix Rhodiolaes, 25 parts of Stigma Crocis, 23 parts of Cortex Moutans, 23 parts, Rhizoma Gastrodiae, 24 parts of Rhizoma Polygoni Cuspidati, 24 parts of Rhizoma Belamcandae, 24 parts of Radix Bupleuri, 38 parts of Radix orixae japonicaes, 24 parts of Flos Albiziaes, 23 parts of Flos Rosae Chinensiss, 23 parts of Herb Gynostemmae Pentaphylli, 25 parts of Radix gynurae segeti, 23 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Radix Scrophulariaes, 14 parts of Radix Sophorae Flavescentiss, 37 parts of Cortex Phellodendris, 500 ~ 1000 parts of Plumbum preparatiums, 1000 ~ 2000 parts of Oleum sesami,
Preferably, described outer plaster is made up of the dry raw material of following weight portion: 0.8 part of glycyrrhizic acid dipotassium, 3 parts of trehaloses, 4.5 parts, Folium olive, 7 parts, Cera Flava, 6 parts of squalanes, 2.5 parts of dimethyl sulfones.
On described carrier, be bonded with protecting film, protecting film is bonded in the carrier surface relative with internal layer plaster bonding plane, and protecting film shape is identical with support shapes, and carrier adopts pure cotton fabric or non-woven fabrics material, and protecting film is plastic material or paper.
Described outer plaster and internal layer plaster are according to weight ratio 1:1 ~ 8.
The thickness ratio of the thickness of described outer plaster and internal layer plaster is 1:2 ~ 5
A preparation method for the treatment of the plaster of cervical spondylosis lumbar spondylosis, is characterized in that, adopts following steps:
1) by 20 ~ 30 parts of dry raw material Coriolous Dersicolor (Fr.) Quel, 40 ~ 50 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 20 ~ 30 parts of Grifola frondosa, 40 ~ 50 parts of Radix Scutellariaes, 40 ~ 50 parts of Radix Et Rhizoma Rhei, 40 ~ 50 parts of the Radixs Angelicae Dahuricae, 40 ~ 50 parts of Geckos, 20 ~ 30 parts, Semen Persicae, 40 ~ 50 parts of Semen Ziziphi Spinosaes, 20 ~ 30 parts of Fructus Caricae, 20 ~ 30 parts, Fructus Pruni pseudocerasi, 20 ~ 30 parts of Fructus Hippophaes, 30 ~ 40 parts of Semen Aesculies, 20 ~ 30 parts of the Radixs Astragali, 20 ~ 30 parts of Folium Ginkgos, 40 ~ 50 parts of Galla Chinensiss, 20 ~ 30 parts of Radix Rhodiolaes, 20 ~ 30 parts of Stigma Crocis, 20 ~ 30 parts of Cortex Moutans, 20 ~ 30 parts, Rhizoma Gastrodiae, 20 ~ 30 parts of Rhizoma Polygoni Cuspidati, 20 ~ 30 parts of Rhizoma Belamcandae, 20 ~ 30 parts of Radix Bupleuri, 30 ~ 40 parts of Radix orixae japonicaes, 20 ~ 30 parts of Flos Albiziaes, 20 ~ 30 parts of Flos Rosae Chinensiss, 20 ~ 30 parts of Herb Gynostemmae Pentaphylli, 20 ~ 30 parts of Radix gynurae segeti, 20 ~ 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 ~ 15 parts of Radix Scrophulariaes, 10 ~ 15 parts of Radix Sophorae Flavescentiss, 30 ~ 40 parts of Cortex Phellodendris were pulverized respectively 10 ~ 20 mesh sieves and obtained medical material granules, medical material granule were put under the mixed liquor room temperature of 2500 ~ 5000 parts of ethanol and water and were soaked 30 ~ 60 days, soaked to finish to filter medical material granule and obtain lixiviating solution, and dry lixiviating solution obtains lixiviate powder,
2) by 15 ~ 25 parts of dry raw material Caulis Spatholobis, 10 ~ 20 parts of Caulis Polygoni Multiflori, 20 ~ 30 parts of Caulis Loniceraes, 10 ~ 20 parts of Radix Aconiti Preparatas, 10 ~ 20 parts of Herba Asaris, 10 ~ 20 parts of Radix Dipsacis, 10 ~ 20 parts of the Cortexs Eucommiae, 10 ~ 20 parts of Radix Aconiti Lateralis Preparatas, 10 ~ 20 parts of Flos Magnoliaes, 10 ~ 20 parts of Radix cocculi laurifoliis, 10 ~ 20 parts of Radix Angelicae Pubescentiss, 10 ~ 20 parts of Herba Rosmarini Officinaliss, 10 ~ 20 parts of Ramulus Sambuci Williamsii, 5 ~ 10 parts of Benzoinumes, 5 ~ 10 parts of Sanguis Draxonis, 10 ~ 20 parts of Radix Angelicae Sinensis, 10 ~ 20 parts of Cortex Cinnamomis, 10 ~ 20 parts of medical material granules of pulverizing respectively 30 ~ 40 mesh sieves acquisitions of 5 ~ 10 parts, Fructus Capsici and Herba Pelargonii Graveolentis are put into Oleum sesami, soak at room temperature 60 ~ 90 days, remove by filter and obtain medicine oil,
3) will after 5 ~ 10 parts of Os Draconis (calcined)s, 5 ~ 10 parts of Pheretimas, 5 ~ 10 parts of Scolopendras, 5 ~ 10 parts of Scorpios, 5 ~ 10 parts of Hirudos, 5 ~ 10 parts of Bombyx Batryticatus, 10 ~ 15 parts of the Limaxs of shelling, 5 ~ 10 parts of Cordyceps, 5 ~ 10 parts of Olibanums, 5 ~ 10 parts of Myrrhas, 5 ~ 10 parts of Endoconcha Sepiaes, 1 ~ 3 part of Borneolum Syntheticum, 2 ~ 5 parts of Colophonium, 2 ~ 5 parts of pulverizing of succinum, be mixed, cross 200 ~ 300 mesh sieves and obtain medicinal powder;
4) in pot, pour step 2 into) the middle medicine oil obtaining, be heated to 70 ~ 100 DEG C of oil temperatures, put into Plumbum preparatium powder, by step 2) in obtain lixiviate powder pour in pot, endure while becoming wire drawing shape to medicine oil, pour the medicinal powder obtaining in step 3) into, after stirring evenly, be heated at 100 ~ 130 DEG C and keep 2 ~ 5 minutes, obtain internal layer plaster mastic; Cease fire and treat that mastic temperature is down to 60 ~ 70 DEG C, take internal layer plaster mastic and be coated on carrier, be pressed into internal layer plaster medicine cake;
5) to adding 1 ~ 10 part, Cera Flava and 1 ~ 5 part of squalane in pot, being heated to 70 ~ 80 DEG C of temperature, 1 ~ 5 minute heat time heating time; In heating process, while stirring to add in pot 1 ~ 5 part, 1 ~ 5 part, Folium olive powder, 1 ~ 5 part of dimethyl sulfone, trehalose while stirring family's heat extremely, stop heating in backward pot and add 0.5 ~ 2 part of glycyrrhizic acid dipotassium to stir well, obtain outer plaster mastic; In the time of 65 ~ 80 DEG C of outer plaster mastic temperature, while hot outer plaster mastic is coated in to the outside of the internal layer plaster medicine cake that step 4) obtains, outer plaster mastic coating zone covers and is greater than the coating zone of internal layer mastic; The outer thickness of plaster and the thickness ratio of internal layer plaster are 1:2 ~ 5; After outer plaster is cooling and get final product;
Ethanol described in step 1) and the mixed liquor of water adopt ethanol and water to mix according to weight ratio 1 ~ 2:1.
The method of the dry lixiviating solution described in step 1) be under normal pressure to lixiviating solution constant temperature drying, 100 DEG C of bake out temperatures, obtain lixiviate powder; Or the method for described dry lixiviating solution is that the ethanol of under normal pressure, lixiviating solution heated at constant temperature to 79 ~ 80 DEG C being removed in lixiviating solution obtains concentrated lixiviating solution, concentrated frozen lixiviating solution is carried out to vacuum lyophilization and remove moisture acquisition lixiviate powder
Described in step 5), Folium olive powder adopts dry raw material Folium olive was pulverized to 500 ~ 600 mesh sieves acquisitions.
Side of the present invention separates:
Os Draconis (calcined), these product be ancient times mammal as if the fossil of the skeleton of class, rhinoceros class, Hippocampal cortex etc., chemical composition]: main hydroxyl calcium phosphate (hydroxyapatite); Still contain the elements such as a small amount of calcium carbonate and ferrum, aluminum, magnesium, manganese, strontium. by the Os Draconis (calcined) of outwash, put in crucible or in other container and be calcined to and be popular in, taking-up is dried in the air cool, pulverizes.Sweet, puckery, flat.Calmness, arresting sweating arresting seminal emission, promoting tissue regeneration and ulcer healing.For neurasthenia, cardiopalmus, insomnia, dreaminess, spontaneous perspiration, night sweat, seminal emission, the enuresis, metrorrhagia, leukorrhagia; External is controlled skin infection and is burst and do not hold back for a long time.
Pheretima is salty, cold.Return liver, spleen, urinary bladder channel.Heat clearing away arresting convulsion, dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
Scolopendra, pungent, temperature; Poisonous.Return Liver Channel.Endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.
Scorpio, pungent, flat; Poisonous.Return Liver Channel.Endogenous wind stopping spasmolytic, dispersing pathogen accumulation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Hirudo, salty, bitter, flat; Slightly poisonous.Return Liver Channel.Removing blood stasis, removing blood stasis, stimulates the menstrual flow.For lump in the abdomen mass in the abdomen, blood stasis amenorrhea, injury from falling down.
Bombyx Batryticatus, salty, pungent, flat.Return liver, lung, stomach warp.Expelling wind for relieving convulsion, dissipating phlegm and resolving masses.For convulsion with spasms, laryngopharynx swelling and pain, skin pruritus, submandibular lymph nodes inflammation, facial paralysis.
Limax, Limax band shell.Salty, cold.Slightly poisonous.Heat-clearing and toxic substances removing, diuresis.For carbuncle furunculosis, anal fistula, dysuria.Heat clearing away, detumescence, removing toxic substances.Control wind heat infantile convulsion, quench one's thirst, sore throat, mumps, scrofula, carbuncle, hemorrhoid, proctoptosis, centipete bite.The preferred escargot (snails) of Limax or Chinese Limax in the present invention.
Cordyceps, sweet, flat.Return lung, kidney channel.Invigorating the lung and the kidney, hemostasis and phlegm.For chronic cough dyspnea due to deficiency, chronic cough spitting of blood, impotence and seminal emission, soreness of waist and knee joint.
Olibanum, property is arduous, temperature.Enter the heart, liver, spleen channel.Function is regulating qi and activating blood, and analgesic therapy, chases after poison.Cure mainly: coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Myrrha, property hardship, flat.GUIXIN, liver, spleen channel.Function is loose blood and relieving pain, detumescence and promoting granulation.For ulcer sore pain, trusted subordinate, all pains of muscles and bones, traumatic blood stasis, external can expelling pus and promoting granulation.Promoting blood circulation to remove blood stasis analgesia.External has convergence and antiinflammation.In addition various skin tinea bacterium is had to inhibitory action in various degree.And can suppress tubercule bacillus.
Endoconcha Sepiae, property is salty, puckery, temperature.Return spleen, kidney channel.Astringing to arrest bleeding, relieving leukorrhea by astringents, antacid, sore.Be used for the acid regurgitation of having a stomachache, hematemesis and epistaxis, metrorrhagia is had blood in stool, emission and spermatorrhea, leucorrhea with red and white discharge; Peptic Ulcers.External treatment bleeding due to trauma, the many pus of skin ulcer.
Borneolum Syntheticum, property is pungent, bitter, is slightly cold.GUIXIN, spleen, lung meridian.The refreshment of having one's ideas straightened out, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors stupor, conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Colophonium, property hardship, sweet, warm.Slightly poisonous.Enter liver, spleen channel.Dispeiling pathogenic wind and removing dampness, granulation promoting pain relieving, is applicable to carbuncle furuncle infections, eczema, traumatic hemorrhage, burn and scald
Succinum, property is sweet, flat.Enter the heart, liver, small intestine meridian.Calmness, diuresis, invigorates blood circulation.For infantile convulsion, epilepsy, cardiopalmus, insomnia, dysuria, dysurea, hematuria, amenorrhea.
Caulis Spatholobi, nature and flavor hardship, sweet, temperature.Return liver, kidney channel.Function cures mainly: enrich blood, invigorate blood circulation, dredging collateral.For menoxenia, blood deficiency and yellow complexion, paralysis and numbness, rheumatic arthralgia.
Caulis Polygoni Multiflori, nature and flavor are sweet, flat.GUIXIN, Liver Channel.Function cures mainly: nourishing blood to tranquillize the mind, dispelling wind and removing obstruction in the collateral.For insomnia and dreamful sleep, blood deficiency general pain, rheumatic arthralgia; External treatment skin pruritus.
Caulis Lonicerae, sweet, cold.Attach to the lung and stomach meridians.Heat-clearing and toxic substances removing, dispelling wind dredging collateral.For epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle skin infection, rheumatism pyretic arthralgia, redness and swelling of joints burning pain.
Radix Aconiti Preparata, property is pungent, bitter, heat.GUIXIN, liver,kidney,spleen warp.Function is expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Herba Asari, nature and flavor: pungent, temperature.Return lung meridian, kidney channel, heart channel, Liver Channel, gallbladder meridian, spleen channel; Effect: cold expelling induces sweat; Wind-expelling pain-stopping; Warming the lung to resolve fluid-retention, sensible; Cure mainly: exterior syndrome due to wind-cold, headache, toothache, rheumatic arthralgia, phlegm retention cough with asthma, nasal obstruction, nasal sinusitis, aphtha, separately has antiinflammatory, immunosuppressant, local anesthesia effect.
Radix Dipsaci, invigorating the liver and kidney, reuniting the fractured tendons and bones, blood circulation regulating.Control aching pain in waist and back, the foot and knee being feeble, vaginal bleeding during pregnancy, metrorrhagia, leukorrhagia, seminal emission, traumatic injury, incised wound, anal fistula, carbuncle skin ulcer is swollen.
The Cortex Eucommiae, nature and flavor are sweet micro-pungent, temperature.Return liver, kidney channel.Function is invigorating the liver and kidney, and bone and muscle strengthening is antiabortive.Cure mainly: spinal column ache, foot and knee flaccidity, dribbling urination, uncontrolled urination is itched, and vaginal bleeding during pregnancy is wanted to fall, hypertension.
Radix Aconiti Lateralis Preparata, pungent, sweet, hot greatly; Poisonous.GUIXIN, kidney, spleen channel.Recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, by wind-cold damp pathogen.For YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Flos Magnoliae, pungent, temperature.Attach to the lung and stomach meridians.Dispersing wind and cold, clearing the nasal passage.For headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.
Radix cocculi laurifolii, bitter, acrid, cold.Return bladder; Kidney; Spleen; Lung meridian.Wind-expelling pain-stopping, inducing diuresis to remove edema, removing toxic substances, blood pressure lowering.For rheumatic arthritis, intercostal neuralgia, acute nephritis, urinary tract infection, hypertension, rheumatic heart disease, edema; Venom is controlled in external.
Radix Angelicae Pubescentis, property is pungent, bitter, tepor.Function is expelling wind and dampness, pain relieving, for rheumatic arthralgia, soreness of waist and knee joint, YIN-cold headache, facial paralysis mouth fish sticking its mouth out of the water.
Herba Rosmarini Officinalis, acrid in the mouth; Warm in nature.Diaphoresis; Spleen invigorating; Calm the nerves; Pain relieving.Main various headaches; Prevent early stage alopecia
Ramulus Sambuci Williamsii, sweet, bitter, flat.Return Liver Channel.Reunion of bone, promoting blood circulation and stopping pain, expelling wind and removing dampness.For fracture, traumatic injury, rheumatic arthritis, gout, Kaschin-Beck disease, acute and chronic nephritis; Wound hemorrhage is controlled in external.
Benzoinum is pungent, bitter, flat.GUIXIN, spleen channel.Open and steal clear god, promoting flow of QI and blood, pain relieving.For apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors stupor, trusted subordinate's pain, puerperal blood faints, infantile convulsion.
Sanguis Draxonis, nature and flavor: sweet, salty, flat.Gui Jing: GUIXIN, Liver Channel.Function cures mainly: removing blood stasis and relieving pain, hemostasia and promoting granulation.Be used for falling flutterring and lose, ecchymoma due to internal injury; Continuous bleeding due to traumatic injury.
Radix Angelicae Sinensis, property sweet, acrid, warm.Return liver, the heart, spleen channel.Function is invigorated blood circulation for enriching blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For rheumatic arthralgia, injury from falling down, blood deficiency and yellow complexion, dizzy cardiopalmus, asthenia cold abdominalgia, dryness of the intestine constipation.
Cortex Cinnamomi, pungent, sweet, hot greatly.Return kidney, spleen, the heart, Liver Channel.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, chills and pain of the waist and kness, suffers from a deficiency of the kidney and breathes heavily, dizziness due to yang deficiency, and conjunctival congestion pharyngalgia, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, colic of cold type, renal mass, amenorrhea, dysmenorrhea.
Fructus Capsici, acrid in the mouth; Hot in nature.Return spleen; Stomach warp.Warming spleen and stomach for dispelling cold; The therapeutic method to keep the adverse QI flowing downwards helps digestion.The main cold syndrome of the stomach stagnation of QI; Abdominal distention; Vomiting; Dysentery; Rheumatalgia; Chilblain.
Herba Pelargonii Graveolentis, acrid in the mouth; Warm in nature.Lung; Liver Channel.Expelling wind and removing dampness; Promoting the circulation of QI to relieve pain; Parasite killing.Main air pain of dampness syndrome; Hernia; Eczema scrotum; Scabies.
Coriolous Dersicolor (Fr.) Quel, sweet; Light; Be slightly cold.Return liver; Spleen; Lung meridian.Invigorating spleen to remove dampness; Relieving cough and asthma; Heat-clearing and toxic substances removing; Antitumor.Main chronic active hepatitis; Hepatitis interstitialis chronica; Chronic bronchitis; Infantile spasm bronchitis; Laryngopharynx swelling and pain; Kinds of tumors; Rheumatoid arthritis; Improve body's immunity, krestin (PSK) can suppress the formation and development of atheromatous plaque effectively.Krestin can improve Mouse and rat learning and memory function, to learning and memory in rats obstacle due to scopolamine, improves significantly.
Hericium erinaceus (Bull. Ex Fr.) Pers., sweet, flat.Profit the five internal organs are aid digestion.Cure mainly dyspepsia, neurasthenia, physical weakness, insomnia and dreamful sleep.
Grifola frondosa, the extract of Grifola frondosa has opposing HIV (human immunodeficiency virus), treatment breast carcinoma, pulmonary carcinoma, hepatocarcinoma, lenitive effect; Deng in addition, its also has following several effects in addition: reduce insulin resistant, strengthen the sensitivity of human body to insulin, contribute to control blood glucose; Suppressing adipose cell piles up; Reduce blood pressure; Enhancing immunity.
Radix Scutellariae, hardship, cold.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.Antiinflammatory, anti-allergy action; Hepatic cholagogic effect; Blood pressure lowering, diuresis, calmness, refrigeration function; Aldose reductase inhibitory action.For infectious hepatitis, acute biliary infection, lead poisoning, heat-clearing and toxic substances removing, vomiting and nausea uncomfortable in chest, cough due to lung-heat, tumor sore frequent fetal movement.
Radix Et Rhizoma Rhei, nature and flavor: hardship, cold.Gui Jing: return spleen, stomach, large intestine, liver, pericardium channel.Function cures mainly: purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, heat in blood is told nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.The hemostasis of charred Radix Et Rhizoma Rhei cooling blood and removing stasis.There is stasis of blood hemorrhage for heat in blood.
The Radix Angelicae Dahuricae, nature and flavor are pungent, temperature.Enter lung, spleen, stomach warp.For Yangming Channel guiding drug.Expelling wind and removing dampness; Logical surreptitiously pain relieving; Detumescence and apocenosis.Main headache due to common cold; Supraorbital bone pain; Toothache; Nasal obstruction; Nasal sinusitis; Domination of damp pathogen chronic diarrhea; Women leucorrhea; Ulcer sores; Venom.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.The cold expelling that induces sweat, wind-expelling pain-stopping, clearing the nasal passage, dampness leukorrhagia stopping, detumescence and apocenosis.Control headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp stomachache, hemorrhoidal hamorrhage anal fistula, leucorrhea with red and white discharge, ulcer sores, skin pruritus due to dryness, scabies.
Gecko, Gecko is removed scale and cephalopodium, is cut into small pieces.Nature and flavor are salty, flat.Return lung, kidney channel.Function cures mainly: invigorating the lung and the kidney, improving inspiration by invigorating kidney-QI Dingchuan, supporing yang benefit essence.For dyspnea due to deficiency tachypnea, chronic cough hemoptysis, impotence and seminal emission.
Semen Persicae is flat; Bitter, sweet; GUIXIN, liver, large intestine channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation.For amenorrhea, dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, injury from falling down, dryness of the intestine constipation.
Semen Ziziphi Spinosae is flat; Sweet, sour; GUIXIN, liver, gallbladder meridian.Function cures mainly: tonifying liver, and mind calming, arresting sweating, promotes the production of body fluid.For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound is thirsty
Fructus Caricae, nature and flavor are sweet, flat.Function cures mainly: invigorating the stomach and promoting digestion, nourishing lactogenic, channels sootheing and network vessel quickening.For weakness of the spleen and stomach, inappetence, hypogalactia, Fengshi Guanjie pain, numb limbs and tense tendons, Stomach duodenum ulcer pain.
Fructus Pruni pseudocerasi, sweet; Temperature; Nontoxic.Spleen; Stomach; Kidney channel.Buxue Yishen, main diarrhea due to hypofunction of the spleen, emission due to deficiency of the kidney, lumbago and skelalgia, extremity are meciless, paralysis.
Fructus Hippophae, sour, puckery, temperature.Eliminating phlegm and stopping cough, relieving dyspepsia, promoting blood circulation to remove blood stasis.For cough with copious phlegm, dyspepsia, abdominal pain due to retention of food, blood stasis amenorrhea, falls and flutters congestive edema.
Semen Aesculi, sweet, temperature.Return liver, stomach warp.Regulating the flow of QI to ease the stomach, and stomach and alleviating pain.Vexed for breast abdominal distention, gastralgia.
The Radix Astragali, sweet, temperature.Return lung, spleen channel.Invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.
Folium Ginkgo is sweet, bitter, puckery, flat.GUIXIN, lung meridian.Astringe the lung, relieving asthma, blood circulation promoting and blood stasis dispelling, pain relieving.For cough and asthma due to lung deficiency; Coronary heart disease, angina pectoris, hyperlipidemia.
Galla Chinensis is sour, puckery, cold.Return lung, large intestine, kidney channel.The pathogenic fire reducing of astringing the lung, relieving diarrhea with astringents, arresting sweating hemostasis, removing dampness sore.For chronic cough of deficiency lung, lung-heat phlegmatic cough, chronic diarrhea chronic dysentery, night sweat, quenches one's thirst, the hemorrhoidal bleeding of having blood in stool, traumatic hemorrhage, carbuncle sore tumefacting virus, Skin wet and rotten.
Radix Rhodiolae, cold; Sweet; Puckery.Return lung meridian.QI invigorating lung heat clearing; Fructus Alpiniae Oxyphyllae is nourished heart; Hemostasis with astringents; Dissipating blood stasis for subsidence of swelling.Main deficiency of vital energy and physically weak; Fear of cold after being ill; Shortness of breath and fatigue; Cough due to lung-heat; Spitting of blood; Leucorrhea diarrhoea; Traumatic injury; Burn and scald; Neurosis; Altitude sickness.
Stigma Croci, nature and flavor are sweet, flat.Enter the heart, Liver Channel.Function cures mainly: blood circulation promoting and blood stasis dispelling, dispersing stagnation and relieving accumulation of pathogens.Control troubled thoughts pent-up, chest and diaphragm painful abdominal mass is vexed, spits blood, and typhoid fever is gone mad, frightened fear in a trance, women's amenorrhea, postnatal blood stasis stomachache, tumbling and swelling.
Cortex Moutan, bitter, pungent, be slightly cold.GUIXIN, liver, kidney channel.Clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling.For maculae caused by violent heat pathogen, hematemesis and epistaxis, night fever abating at dawn, lossless hectic fever due to YIN-deficiency, amenorrhea dysmenorrhea, carbuncle sore tumefacting virus, falls and flutters the pain of injury.
Rhizoma Gastrodiae, sweet, flat.Return Liver Channel.Suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Be used for having a headache dizzy, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.
Rhizoma Polygoni Cuspidati, micro-hardship, is slightly cold.Return liver, gallbladder, lung meridian.Expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm.For arthralgia, jaundice due to damp-heat, amenorrhea, lump in the abdomen, burn due to hot liquid or fire, injury from falling down, carbuncle sore tumefacting virus, cough with copious phlegm.
Rhizoma Belamcandae, hardship, cold.Return lung meridian.Heat-clearing and toxic substances removing, expectorant, sore-throat relieving.For the pent-up of pyretic toxicity phlegm-fire, laryngopharynx swelling and pain, accumulation and obstruction of sputum, cough and asthma.
Radix Bupleuri, hardship, is slightly cold.Return liver, gallbladder meridian.Reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
Radix orixae japonicae, pungent, heat.Return stomach, large intestine channel.Warming spleen and stomach for dispelling cold, the therapeutic method to keep the adverse QI flowing downwards, expectorant.For gastrofrigid vomiting, stomachache is had loose bowels, inappetence, epilepsy abundant expectoration.
Flos Albiziae, sweet, flat.GUIXIN, Liver Channel.Resolving stagnation for tranquilization.For irritability, melancholy insomnia.
Flos Rosae Chinensis, sweet, temperature.Return Liver Channel.Promoting blood flow to regulate menstruation, loose poison detumescence.Flower: for menoxenia, dysmenorrhea, carbuncle furuncle and phyma poison, tuberculous lymphadenitis (not diabrosis).Leaf: tuberculous lymphadenitis, traumatic injury.Root: traumatic injury, leucorrhea, seminal emission.
Herb Gynostemmae Pentaphylli, bitter in the mouth; Micro-sweet; Cool in nature.Return lung; Spleen; Kidney channel.Heat clearing away; Tonify deficiency; Removing toxic substances.Main body void is weak; Nephrasthenia emission; Leukopenia; Hyperlipemia; Viral hepatitis; Chronic gastroenteritis; Chronic tracheitis.
Radix gynurae segeti, sweetness and bitterness, temperature.Invigorate blood circulation, detumescence.Control traumatic injury, the stasis of blood is long-pending to swell and ache, carbuncle skin ulcer abscess, acute mastitis
The Rhizoma Atractylodis Macrocephalae, bitter, sweet, temperature.Return spleen, stomach warp.Invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Rhizoma Atractylodis Macrocephalae spleen invigorating, stomach function regulating, antiabortive.For insufficiency of the spleen lack of appetite, the loose stool of having loose bowels, frequent fetal movement.
Radix Scrophulariae, nature and flavor are sweet, bitter, salty, are slightly cold.Return lung, stomach, kidney channel.Function cures mainly: removing heat from blood YIN nourishing, eliminating fire and detoxication.For consumption of YIN caused by febrile disease, crimson tongue excessive thirst, maculae caused by violent heat pathogen, constipation is hindered in Tianjin, hectic fever due to YIN-deficiency chronic cough, conjunctival congestion, pharyngalgia, scrofula, diphtheria, carbuncle sore tumefacting virus.
Radix Sophorae Flavescentis, nature and flavor hardship, cold.GUIXIN, liver, stomach, large intestine, urinary bladder channel.Function cures mainly: heat clearing and damp drying, parasite killing, diuresis.For hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Cortex Phellodendri, hardship, cold.Return kidney, urinary bladder channel.Heat clearing and damp drying, pathogenic fire purging is except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Folium olive, sweet puckery acid, flat.Lung heat clearing, sore-throat relieving, promotes the production of body fluid, removing toxic substances.Control laryngopharynx swelling and pain, excessive thirst, cough is spitted blood, bacillary dysentery, epilepsy, separates tetrodotoxin, TTX and alcoholism, treatment dermatosis;
Plumbum preparatium, pungent saltiness is trembled with fear, and heavy the moon is walked blood, and pendant expectorant is brought down a fever, and energy town is contrary frightened to treat, pain relieving granulation promoting, and can admittedly take off by parasite killing.Plumbum preparatium chemical composition is lead orthoplumbate.
Oleum sesami, nature and flavor are sweet, cool.Enter meridian of Hand-YANG MING.Function cures mainly moistening dryness for relaxing bowels, removing toxic substances, granulation promoting.Control dryness of the intestine constipation, ascarid, abdominal pain due to retention of food, skin ulcer is swollen, ulcer, scabies, chapped skin.
Compared with prior art, the beneficial effect that plaster for the treatment of cervical spondylosis lumbar spondylosis of the present invention and preparation method thereof has is:
1, the plaster for the treatment of cervical spondylosis lumbar spondylosis of the present invention can effectively be treated cervical spondylosis and lumbar spondylosis, and Cervical disc herniation and lumbar intervertebral disc deviate to have good curative effect, total effective rate 90%, cure rate 85%.
First the effect that the complication that, plaster of the present invention causes cervical spondylosis lumbar spondylosis has treatment and alleviates.Plaster of the present invention can be repaired the connective tissue of damage, and the connective tissue in making recovers homergy, makes the fibrous ring of intervertebral disc recover elasticity.Applicant, by dredging blood, recovers the microcirculation of joint part, recovers metabolism and the self-repairing capability of connective tissue, regulates the effect of body immunity, recovers gradually the homergy of joint part, and the joint of damage is rejuvenated gradually.Secondly, prevention bony spur forms, the interpolation of dimethyl sulfone can be softened established small bony spur gradually, and reach prevention osseous tissue and regulate the microcirculation of affected part lymph to repair cartilaginous tissue by the coupling of Coriolous Dersicolor (Fr.) Quel, Hericium erinaceus (Bull. Ex Fr.) Pers., Grifola frondosa, Flos Rosae Chinensis and Herb Gynostemmae Pentaphylli by Caulis Spatholobi, Caulis Polygoni Multiflori, Caulis Lonicerae, Radix Aconiti Preparata, Herba Asari, Radix Dipsaci, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Flos Magnoliae, Radix cocculi laurifolii, Radix Angelicae Pubescentis, Sanguis Draxonis, Radix Angelicae Sinensis, Cortex Cinnamomi, Herba Pelargonii Graveolentis adjusting affected part blood circulation, prevention cartilaginous calcification forms bony spur; The interpolation of Os Draconis (calcined), Hirudo, Bombyx Batryticatus, shell Limax and Ligamentum cervi can contribute to supplement the required mine trace element of reparation connective tissue, form the necessary aminoacid of elastin laminin containing helping lend some impetus to this class of the synthetic chondroitin sulfate of fibroblast and glycine, proline and hydroxyproline, can provide nutrition for the reparation of the ligament around vertebra, intervertebral disc, nervous tissue.Finally, plaster of the present invention can be repaired impaired neurocyte, alleviates cervical spondylosis lumbar spondylosis sequela.Nervous tissue's blood oxygen supply minimizing, neurocyte atrophy necrosis that treatment causes because of stagnation of QI and blood.Applicant adds Hericium erinaceus (Bull. Ex Fr.) Pers., Grifola frondosa and Semen Ziziphi Spinosae in the present invention, repairs impaired neurocyte; Also add the composition of invigorating blood circulation and recovered affected part vein microcirculation, for neurocyte transports nutrition.
2, the plaster for the treatment of cervical spondylosis lumbar spondylosis of the present invention have anti-go mouldy, prolong drug useful life's effect, solved that the long-time storage of existing black plaster is easily gone mouldy and the volatile problem of effective ingredient.Plaster of the present invention adopts the two-layer storage of internal layer plaster and outer plaster; when use, heated baking uses after making the outer plaster of internal layer plaster fuse into one into one deck plaster; can ensure to protect in storage drug effect; do not affect again the drug effect infiltration in use procedure, also can make first with the active ingredient of contact skin, skin to be releived and prevented the generation of allergic phenomena.Applicant has designed outer plaster in plaster of the present invention; squalane, Cera Flava, Folium olive and trehalose in outer plaster is mixed, coating, can forms on internal layer plaster surface the protective layer of one deck densification after cooling through step 5) heating of the present invention, can prevent from having in internal layer plaster volatile effective ingredient volatilization and scatter and disappear, can also prevent internal layer plaster the problem of season cracking to occur because of moisture loss.In internal layer plaster, have more protide, oils composition, the design of outer plaster has completely cut off internal layer plaster and has contacted with outside air and also can prevent that antibacterial from infiltrating in internal layer plaster.Applicant's design has added Folium olive in the outer plaster contacting with external environment and trehalose coupling obtains Synergistic antimicrobial antiseptical effect, secondly uses squalane, Cera Flava to cut off the condition of bacteria breed every air and exhausted water.Again, the outer plaster of applicant's design not only can not stop that the drug effect of internal layer plaster absorbs, and also has and improves joint restoring force and promote effect that internal layer plaster absorbs.Applicant's design is used if electric heater, warm-air drier or hair dryer are as roasting plant in the time using plaster of the present invention, outer plaster is toasted, under the condition that outer plaster and internal layer plaster raise in temperature, occur to soften, the softening attenuation of outer plaster is also permeated in internal layer plaster; Due in internal layer plaster, contain with outer plaster in the compatible oiliness composition of squalane, the effective province in internal layer plaster also permeating in outer plaster; This interpenetrates process can very fast completing in the process of heating plaster.Actual by the plaster docile of the present invention after heating on the pars affecta skin of sterilization time, outer plaster and internal layer plaster drug effect interpenetrate and combine together, and and internal layer plaster in effective ingredient under effect, be permeable to subcutaneous affected part short the oozing of squalane.The structural design of plaster of the present invention can effectively be protected internal layer cream the effective elements of the medicine, and applicant designs internal layer plaster between outer plaster and carrier; The coated area of outer plaster is greater than the coated area of internal layer plaster; The coating zone of internal layer plaster mastic is positioned at outer plaster mastic coating zone, internal layer plaster can be enclosed in the closed area that outer plaster and carrier surround, and prevents that drug effect from becoming that long-time ingress of air is oxidized, mouldy or drug effect is scattered and disappeared.Applicant's bonding protective film relative with internal layer plaster sticking veneer on carrier, protecting film has the effect that intercepts volatilization prevention, can prevent that internal layer cream the effective elements of the medicine from seeing through comparatively ventilative carrier volatilization and scattering and disappearing.
3, the plaster docile 14 ~ 20 days for the treatment of cervical spondylosis lumbar spondylosis of the present invention is without allergic phenomena, can effectively solve the long-time docile of existing black plaster and easily occur the problem of skin allergy, redness, diabrosis.First applicant's design is in the design of outer plaster, although can make outer plaster and internal layer plaster drug effect interpenetrate under heating condition combines together, but can stop that the Plumbum preparatium composition in internal layer plaster directly contacts with large area skin, thereby play the effect that prevents skin diabrosis; Secondly; the glycyrrhizic acid dipotassium that applicant adds in outer Recipe of plaster has good antiallergic effect; design is bonded in pars affecta skin initial stage glycyrrhizic acid diformazan first-selection at plaster and infiltrates through skin; skin is played a protective role; along with the effective ingredient in the plaster prolongation internal layer plaster of stickup time infiltrates through skin; under glycyrrhizic acid dipotassium effect; can obviously reduce the irritated rate of plaster of the present invention; also can prevent in plaster that effective ingredient chafe causes itch, swell and ache, diabrosis, use plaster of the present invention to occur without irritated case for 5 ~ 6 courses for the treatment of.
4, the plaster osmotic effect for the treatment of cervical spondylosis lumbar spondylosis of the present invention is good, can effectively infiltrate into subcutaneously, acts on vertebra and nerve around, muscle and cartilaginous tissue.Applicant has added Radix orixae japonicae in internal layer plaster, goes out to be soluble in the piperine of ethanol, piperine chemical name (E with the mixed liquor lixiviate of crossing ethanol and water, E)-1-[5-(1,3-benzo dioxolanes-5-yl)-1-oxo-2,4-pentadienyl]-piperidines, molecular formula C 17h 19nO 3, molecular weight 285.34.Applicant finds under study for action that piperine can be induced and changes film kinetics and membrane permeation characteristics, promote to permeate in the affected tissue to cervical vertebra, cell of the active ingredient in internal layer plaster, and all there is the effect of good promotion infiltration for water solublity and oil-soluble active ingredient; Applicant also finds that the albumen that piperine induction is relevant to cytoskeleton function is synthetic simultaneously.Applicant the present invention use the kind of Fructus Piperis for Radix orixae japonicae be find Radix orixae japonicae under study for action due to applicant in the content of piperine higher than black pepper in the content of piperine, adopt the leach extraction method of step 1) of the present invention can obtain more piperine, help lend some impetus to the infiltration of internal layer plaster effect.Applicant has added the squalane with human body skin with superior compatibility in outer plaster, and squalane portability active ingredient infiltrates subcutaneous.
Brief description of the drawings
Fig. 1 is plaster structural front view.
Fig. 2 is that plaster structure is along A-A face cutaway view.
Fig. 3 is the partial enlarged drawing in plaster B region.
Wherein: 1, carrier; 2, outer plaster; 3, internal layer plaster; 4, protecting film.
Detailed description of the invention
Embodiment 1 ~ 3rd, the specific embodiment of plaster for the treatment of cervical spondylosis lumbar spondylosis of the present invention and preparation method thereof, wherein embodiment 1 is preferred forms.
A kind of plaster for the treatment of cervical spondylosis lumbar spondylosis of the present invention comprises carrier 1, outer plaster 2 and internal layer plaster 3, and internal layer plaster 3 is between outer plaster 2 and carrier 1; With reference to Fig. 1, the coated area of outer plaster 2 is greater than the coated area of internal layer plaster 3; The coating zone of internal layer plaster 3 mastic is positioned at outer plaster 2 mastic coating zones; On carrier 1, be bonded with protecting film 4, protecting film 4 is bonded in carrier 1 surface relative with internal layer plaster 3 bonding planes, and protecting film shape is identical with support shapes, and carrier 1 adopts pure cotton fabric or non-woven fabrics material, and protecting film 4 is plastic material or paper, preferably PE film.Protecting film 4 can be torn and separate with carrier 1.Described outer plaster 2 and internal layer plaster 3 are taken according to weight ratio 1:1 ~ 7.The thickness ratio of the thickness of described outer plaster 2 and internal layer plaster 3 is 1:2 ~ 5.
embodiment 1
Internal layer plaster 3 is made up of the dry raw material of following weight portion: 7 parts of Os Draconis (calcined)s, 8 parts of Pheretimas, 7 parts of Scolopendras, 7 parts of Scorpios, 8 parts of Hirudos, 9 parts of Bombyx Batryticatus, shell 13 parts of Limaxs, 9 parts of Cordyceps, 8 parts of Olibanums, 7 parts of Myrrhas, 8 parts of Endoconcha Sepiaes, 1.5 parts of Borneolum Syntheticums, 2 parts of Colophonium, 3 parts of succinums, 18 parts of Caulis Spatholobis, 14 parts of Caulis Polygoni Multiflori, 23 parts of Caulis Loniceraes, 15 parts of Radix Aconiti Preparatas, 16 parts of Herba Asaris, 14 parts of Radix Dipsacis, 14 parts of the Cortexs Eucommiae, 15 parts of Radix Aconiti Lateralis Preparatas, 14 parts of Flos Magnoliaes, 16 parts of Radix cocculi laurifoliis, 14 parts of Radix Angelicae Pubescentiss, 17 parts of Herba Rosmarini Officinaliss, 14 parts of Ramulus Sambuci Williamsii, 7 parts of Benzoinumes, 7 parts of Sanguis Draxonis, 16 parts of Radix Angelicae Sinensis, 14 parts of Cortex Cinnamomis, 7 parts, Fructus Capsici, 16 parts of Herba Pelargonii Graveolentiss, 23 parts of Coriolous Dersicolor (Fr.) Quel, 47 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 25 parts of Grifola frondosa, 47 parts of Radix Scutellariaes, 45 parts of Radix Et Rhizoma Rhei, 45 parts of the Radixs Angelicae Dahuricae, 45 parts of Geckos, 23 parts, Semen Persicae, 487 parts of Semen Ziziphi Spinosaes, 23 parts of Fructus Caricae, 25 parts, Fructus Pruni pseudocerasi, 25 parts of Fructus Hippophaes, 37 parts of Semen Aesculies, 24 parts of the Radixs Astragali, 24 parts of Folium Ginkgos, 45 parts of Galla Chinensiss, 25 parts of Radix Rhodiolaes, 25 parts of Stigma Crocis, 23 parts of Cortex Moutans, 23 parts, Rhizoma Gastrodiae, 24 parts of Rhizoma Polygoni Cuspidati, 24 parts of Rhizoma Belamcandae, 24 parts of Radix Bupleuri, 38 parts of Radix orixae japonicaes, 24 parts of Flos Albiziaes, 23 parts of Flos Rosae Chinensiss, 23 parts of Herb Gynostemmae Pentaphylli, 25 parts of Radix gynurae segeti, 23 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Radix Scrophulariaes, 14 parts of Radix Sophorae Flavescentiss, 37 parts of Cortex Phellodendris, 500 ~ 1000 parts of Plumbum preparatiums, 1000 ~ 2000 parts of Oleum sesami,
Outer plaster 2 is made up of the dry raw material of following weight portion: 0.8 part of glycyrrhizic acid dipotassium, 3 parts of trehaloses, 4.5 parts, Folium olive, 7 parts, Cera Flava, 6 parts of squalanes, 2.5 parts of dimethyl sulfones.
Preparation method is as follows:
1) by dry raw material Coriolous Dersicolor (Fr.) Quel, Hericium erinaceus (Bull. Ex Fr.) Pers., Grifola frondosa, Radix Scutellariae, Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae, Gecko, Semen Persicae, Semen Ziziphi Spinosae part, Fructus Caricae, Fructus Pruni pseudocerasi, Fructus Hippophae, Semen Aesculi, the Radix Astragali, Folium Ginkgo, Galla Chinensis, Radix Rhodiolae, Stigma Croci, Cortex Moutan, Rhizoma Gastrodiae, Rhizoma Polygoni Cuspidati, Rhizoma Belamcandae, Radix Bupleuri, Radix orixae japonicae, Flos Albiziae, Flos Rosae Chinensis, Herb Gynostemmae Pentaphylli, Radix gynurae segeti, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Radix Sophorae Flavescentis, Cortex Phellodendri was pulverized respectively 10 mesh sieves and obtained medical material granule, medical material granule is put under the mixed liquor room temperature of 3000 parts of ethanol and water and soaked 30 ~ 60 days, described ethanol and the mixed liquor of water adopt ethanol and water to mix according to weight ratio 2:1, soak end immersion end filtration medical material granule and obtain lixiviating solution, the ethanol of under normal pressure, lixiviating solution heated at constant temperature to 79 ~ 80 DEG C being removed in lixiviating solution obtains concentrated lixiviating solution, concentrated frozen lixiviating solution is carried out to vacuum lyophilization and remove moisture acquisition lixiviate powder,
2) by dry raw material Caulis Spatholobi, Caulis Polygoni Multiflori, Caulis Lonicerae, Radix Aconiti Preparata, Herba Asari, Radix Dipsaci, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Flos Magnoliae, Radix cocculi laurifolii, Radix Angelicae Pubescentis, Herba Rosmarini Officinalis, Ramulus Sambuci Williamsii, Benzoinum, Sanguis Draxonis, Radix Angelicae Sinensis, Cortex Cinnamomi, Fructus Capsici and Herba Pelargonii Graveolentis pulverized respectively the medical material granule that 40 mesh sieves obtain and put into Oleum sesami, soak at room temperature 60 days, removes by filter and obtains medicine oil;
3) Os Draconis (calcined), Pheretima, Scolopendra, Scorpio, Hirudo, Bombyx Batryticatus, the Limax of shelling, Cordyceps, Olibanum, Myrrha, Endoconcha Sepiae, Borneolum Syntheticum, Colophonium, succinum are mixed after pulverizing, cross 200 mesh sieves and obtain medicinal powder;
4) in pot, pour step 2 into) the middle medicine oil obtaining, be heated to 70 ~ 100 DEG C of oil temperatures, put into Plumbum preparatium powder, by step 2) in obtain lixiviate powder pour in pot, endure while becoming wire drawing shape to medicine oil, pour the medicinal powder obtaining in step 3) into, after stirring evenly, be heated at 100 ~ 130 DEG C and keep 3 minutes, obtain internal layer plaster mastic; Cease fire and treat that mastic temperature is down to 60 ~ 70 DEG C, take 15 ~ 65 g plaster mastic and be coated on carrier, be pressed into internal layer plaster medicine cake;
5) in pot, add Cera Flava and squalane, be heated to 70 ~ 80 DEG C of temperature, 3 ~ 5 minutes heat time heating times; In heating process, add Folium olive powder, dimethyl sulfone while stirring in pot, trehalose while stirring family's heat extremely, stops heating in backward pot and adds glycyrrhizic acid dipotassium to stir well, and obtains outer plaster 2 mastic; In the time of 65 ~ 80 DEG C of outer plaster 2 mastic temperature, use while hot brush to brush, outer plaster 2 mastic are coated in to the outside of the internal layer plaster medicine cake that step 4) obtains, outer plaster 2 mastic coating zones cover and are greater than the coating zone of internal layer mastic; After outer plaster 2 is cooling and get final product; The present embodiment ectomesoderm plaster 2 and internal layer plaster 3 are taken and are applied into one and force on according to weight ratio 1:5; The outer thickness of plaster 2 and the thickness ratio of internal layer plaster 3 are 1:3 ~ 4; Folium olive powder adopts dry raw material Folium olive to pulverize 500 mesh sieves and obtains.
embodiment 2
The present embodiment adopts the dry medical material of following weight portion to make:
Described internal layer plaster 3 is made up of the dry raw material of following weight portion: 7 parts of Os Draconis (calcined)s, 7 parts of Pheretimas, 7 parts of Scolopendras, 7 parts of Scorpios, 9 parts of Hirudos, 9 parts of Bombyx Batryticatus, shell 12 ~ 14 parts of Limaxs, 9 parts of Cordyceps, 9 parts of Olibanums, 7 parts of Myrrhas, 9 parts of Endoconcha Sepiaes, 3 parts of Borneolum Syntheticums, 5 parts of Colophonium, 2 ~ 5 parts of succinums, 25 parts of Caulis Spatholobis, 13 parts of Caulis Polygoni Multiflori, 26 parts of Caulis Loniceraes, 17 parts of Radix Aconiti Preparatas, 13 parts of Herba Asaris, 17 parts of Radix Dipsacis, 13 parts of the Cortexs Eucommiae, 17 parts of Radix Aconiti Lateralis Preparatas, 17 parts of Flos Magnoliaes, 13 parts of Radix cocculi laurifoliis, 17 parts of Radix Angelicae Pubescentiss, 13 parts of Herba Rosmarini Officinaliss, 17 parts of Ramulus Sambuci Williamsii, 7 parts of Benzoinumes, 7 ~ 9 parts of Sanguis Draxonis, 13 parts of Radix Angelicae Sinensis, 13 parts of Cortex Cinnamomis, 7 parts, Fructus Capsici, 17 parts of Herba Pelargonii Graveolentiss, 26 parts of Coriolous Dersicolor (Fr.) Quel, 45 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 26 parts of Grifola frondosa, 45 parts of Radix Scutellariaes, 48 parts of Radix Et Rhizoma Rhei, 48 parts of the Radixs Angelicae Dahuricae, 45 parts of Geckos, 26 parts, Semen Persicae, 45 parts of Semen Ziziphi Spinosaes, 26 parts of Fructus Caricae, 26 parts, Fructus Pruni pseudocerasi, 26 parts of Fructus Hippophaes, 38 parts of Semen Aesculies, 26 parts of the Radixs Astragali, 22 parts of Folium Ginkgos, 48 parts of Galla Chinensiss, 26 parts of Radix Rhodiolaes, 22 parts of Stigma Crocis, 26 parts of Cortex Moutans, 26 parts, Rhizoma Gastrodiae, 26 parts of Rhizoma Polygoni Cuspidati, 26 parts of Rhizoma Belamcandae, 22 parts of Radix Bupleuri, 35 ~ 38 parts of Radix orixae japonicaes, 22 ~ 26 parts of Flos Albiziaes, 26 parts of Flos Rosae Chinensiss, 22 parts of Herb Gynostemmae Pentaphylli, 26 parts of Radix gynurae segeti, 26 parts of the Rhizoma Atractylodis Macrocephalaes, 12 parts of Radix Scrophulariaes, 12 parts of Radix Sophorae Flavescentiss, 35 parts of Cortex Phellodendris, 550 parts of Plumbum preparatiums, 1000 ~ 1100 parts of Oleum sesami,
Described outer plaster 2 is made up of the dry raw material of following weight portion: 1.0 parts of glycyrrhizic acid dipotassiums, 2 parts of trehaloses, 2 parts, Folium olive, 5 parts, Cera Flava, 2 parts of squalanes, 3 parts of dimethyl sulfones.
Preparation method is as follows:
1) by dry raw material Coriolous Dersicolor (Fr.) Quel, Hericium erinaceus (Bull. Ex Fr.) Pers., Grifola frondosa, Radix Scutellariae, Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae, Gecko, Semen Persicae, Semen Ziziphi Spinosae part, Fructus Caricae, Fructus Pruni pseudocerasi, Fructus Hippophae, Semen Aesculi, the Radix Astragali, Folium Ginkgo, Galla Chinensis, Radix Rhodiolae, Stigma Croci, Cortex Moutan, Rhizoma Gastrodiae, Rhizoma Polygoni Cuspidati, Rhizoma Belamcandae, Radix Bupleuri, Radix orixae japonicae, Flos Albiziae, Flos Rosae Chinensis, Herb Gynostemmae Pentaphylli, Radix gynurae segeti, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Radix Sophorae Flavescentis, Cortex Phellodendri was pulverized respectively 10 ~ 20 mesh sieves and obtained medical material granule, medical material granule is put under the mixed liquor room temperature of 2500 ~ 5000 parts of ethanol and water and soaked 30 ~ 60 days, described ethanol and the mixed liquor of water adopt ethanol and water to mix according to weight ratio 1 ~ 2:1, soak end immersion end filtration medical material granule and obtain lixiviating solution, under normal pressure, to lixiviating solution constant temperature drying, 100 DEG C of bake out temperatures, obtain lixiviate powder,
2) by dry raw material Caulis Spatholobi, Caulis Polygoni Multiflori, Caulis Lonicerae, Radix Aconiti Preparata, Herba Asari, Radix Dipsaci, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Flos Magnoliae, Radix cocculi laurifolii, Radix Angelicae Pubescentis, Herba Rosmarini Officinalis, Ramulus Sambuci Williamsii, Benzoinum, Sanguis Draxonis, Radix Angelicae Sinensis, Cortex Cinnamomi, Fructus Capsici and Herba Pelargonii Graveolentis pulverized respectively the medical material granule that 30 ~ 40 mesh sieves obtain and put into Oleum sesami, soak at room temperature 60 ~ 90 days, removes by filter and obtains medicine oil;
3) Os Draconis (calcined), Pheretima, Scolopendra, Scorpio, Hirudo, Bombyx Batryticatus, the Limax of shelling, Cordyceps, Olibanum, Myrrha, Endoconcha Sepiae, Borneolum Syntheticum, Colophonium, succinum are mixed after pulverizing, cross 300 mesh sieves and obtain medicinal powder;
4) in pot, pour step 2 into) the middle medicine oil obtaining, be heated to 70 ~ 100 DEG C of oil temperatures, put into Plumbum preparatium powder, by step 2) in obtain lixiviate powder pour in pot, endure while becoming wire drawing shape to medicine oil, pour the medicinal powder obtaining in step 3) into, after stirring evenly, be heated at 100 ~ 130 DEG C and keep 5 minutes, obtain internal layer plaster mastic; Cease fire and treat that mastic temperature is down to 60 ~ 70 DEG C, take 15 ~ 65 g plaster mastic and be coated on carrier, be pressed into internal layer plaster medicine cake;
5) in pot, add Cera Flava and squalane, be heated to 70 ~ 80 DEG C of temperature, 3 minutes heat time heating times; In heating process, add Folium olive powder, dimethyl sulfone while stirring in pot, trehalose while stirring family's heat extremely, stops heating in backward pot and adds glycyrrhizic acid dipotassium to stir well, and obtains outer plaster 2 mastic; In the time of 65 ~ 80 DEG C of outer plaster 2 mastic temperature, use while hot brush to brush, outer plaster 2 mastic are coated in to the outside of the internal layer plaster medicine cake that step 4) obtains, outer plaster 2 mastic coating zones cover and are greater than the coating zone of internal layer mastic; After outer plaster 2 is cooling and get final product; The present embodiment ectomesoderm plaster 2 and internal layer plaster 3 are taken and are applied into one and force on according to weight ratio 1:2; The outer thickness of plaster 2 and the thickness ratio of internal layer plaster 3 are 1:2; Folium olive powder adopts dry raw material Folium olive to pulverize 600 mesh sieves and obtains.
embodiment 3
The present embodiment adopts the dry medical material of following weight portion to make:
10 parts of Os Draconis (calcined)s, 5 parts of Pheretimas, 10 parts of Scolopendras, 5 parts of Scorpios, 7 parts of Hirudos, 9 parts of Bombyx Batryticatus, shell 15 parts of Limaxs, 10 parts of Cordyceps, 5 parts of Olibanums, 10 parts of Myrrhas, 10 parts of Endoconcha Sepiaes, 1 part of Borneolum Syntheticum, 2 parts of Colophonium, 5 parts of succinums, 25 parts of Caulis Spatholobis, 10 parts of Caulis Polygoni Multiflori, 20 parts of Caulis Loniceraes, 20 parts of Radix Aconiti Preparatas, 20 parts of Herba Asaris, 10 parts of Radix Dipsacis, 20 parts of the Cortexs Eucommiae, 20 parts of Radix Aconiti Lateralis Preparatas, 20 parts of Flos Magnoliaes, 10 parts of Radix cocculi laurifoliis, 10 parts of Radix Angelicae Pubescentiss, 10 parts of Herba Rosmarini Officinaliss, 10 parts of Ramulus Sambuci Williamsii, 5 parts of Benzoinumes, 5 parts of Sanguis Draxonis, 20 parts of Radix Angelicae Sinensis, 10 parts of Cortex Cinnamomis, 5 parts, Fructus Capsici, 20 parts of Herba Pelargonii Graveolentiss, 20 parts of Coriolous Dersicolor (Fr.) Quel, 50 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 30 parts of Grifola frondosa, 50 parts of Radix Scutellariaes, 40 parts of Radix Et Rhizoma Rhei, 40 parts of the Radixs Angelicae Dahuricae, 40 parts of Geckos, 20 parts, Semen Persicae, 40 parts of Semen Ziziphi Spinosaes, 20 parts of Fructus Caricae, 20 parts, Fructus Pruni pseudocerasi, 20 parts of Fructus Hippophaes, 40 parts of Semen Aesculies, 20 parts of the Radixs Astragali, 30 parts of Folium Ginkgos, 50 parts of Galla Chinensiss, 30 parts of Radix Rhodiolaes, 30 parts of Stigma Crocis, 20 parts of Cortex Moutans, 30 parts, Rhizoma Gastrodiae, 30 parts of Rhizoma Polygoni Cuspidati, 20 parts of Rhizoma Belamcandae, 20 parts of Radix Bupleuri, 30 parts of Radix orixae japonicaes, 20 parts of Flos Albiziaes, 20 parts of Flos Rosae Chinensiss, 20 parts of Herb Gynostemmae Pentaphylli, 20 parts of Radix gynurae segeti, 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 ~ 15 parts of Radix Scrophulariaes, 15 parts of Radix Sophorae Flavescentiss, 30 parts of Cortex Phellodendris, 600 ~ 700 parts of Plumbum preparatiums, 1200 ~ 1500 parts of Oleum sesami,
Outer plaster 2 is made up of the dry raw material of following weight portion: 1.5 parts of glycyrrhizic acid dipotassiums, 5 parts of trehaloses, 2 parts, Folium olive, 5 parts, Cera Flava, 3 parts of squalanes, 2 parts of dimethyl sulfones.
Preparation method is as follows:
1) by dry raw material Coriolous Dersicolor (Fr.) Quel, Hericium erinaceus (Bull. Ex Fr.) Pers., Grifola frondosa, Radix Scutellariae, Radix Et Rhizoma Rhei, the Radix Angelicae Dahuricae, Gecko, Semen Persicae, Semen Ziziphi Spinosae part, Fructus Caricae, Fructus Pruni pseudocerasi, Fructus Hippophae, Semen Aesculi, the Radix Astragali, Folium Ginkgo, Galla Chinensis, Radix Rhodiolae, Stigma Croci, Cortex Moutan, Rhizoma Gastrodiae, Rhizoma Polygoni Cuspidati, Rhizoma Belamcandae, Radix Bupleuri, Radix orixae japonicae, Flos Albiziae, Flos Rosae Chinensis, Herb Gynostemmae Pentaphylli, Radix gynurae segeti, the Rhizoma Atractylodis Macrocephalae, Radix Scrophulariae, Radix Sophorae Flavescentis, Cortex Phellodendri was pulverized respectively 10 ~ 20 mesh sieves and obtained medical material granule, medical material granule is put under the mixed liquor room temperature of 2500 ~ 5000 parts of ethanol and water and soaked 30 ~ 60 days, described ethanol and the mixed liquor of water adopt ethanol and water to mix according to weight ratio 1 ~ 2:1, soak end immersion end filtration medical material granule and obtain lixiviating solution, under normal pressure, to lixiviating solution constant temperature drying, 100 DEG C of bake out temperatures, obtain lixiviate powder,
2) by dry raw material Caulis Spatholobi, Caulis Polygoni Multiflori, Caulis Lonicerae, Radix Aconiti Preparata, Herba Asari, Radix Dipsaci, the Cortex Eucommiae, Radix Aconiti Lateralis Preparata, Flos Magnoliae, Radix cocculi laurifolii, Radix Angelicae Pubescentis, Herba Rosmarini Officinalis, Ramulus Sambuci Williamsii, Benzoinum, Sanguis Draxonis, Radix Angelicae Sinensis, Cortex Cinnamomi, Fructus Capsici and Herba Pelargonii Graveolentis pulverized respectively the medical material granule that 30 ~ 40 mesh sieves obtain and put into Oleum sesami, soak at room temperature 60 ~ 90 days, removes by filter and obtains medicine oil;
3) Os Draconis (calcined), Pheretima, Scolopendra, Scorpio, Hirudo, Bombyx Batryticatus, the Limax of shelling, Cordyceps, Olibanum, Myrrha, Endoconcha Sepiae, Borneolum Syntheticum, Colophonium, succinum are mixed after pulverizing, cross 200 mesh sieves and obtain medicinal powder;
4) in pot, pour step 2 into) the middle medicine oil obtaining, be heated to 70 ~ 100 DEG C of oil temperatures, put into Plumbum preparatium powder, by step 2) in obtain lixiviate powder pour in pot, endure while becoming wire drawing shape to medicine oil, pour the medicinal powder obtaining in step 3) into, after stirring evenly, be heated at 100 ~ 130 DEG C and keep 2 ~ 5 minutes, obtain internal layer plaster mastic; Cease fire and treat that mastic temperature is down to 60 ~ 70 DEG C, take 15 ~ 65 g plaster mastic and be coated on carrier, be pressed into internal layer plaster medicine cake;
5) in pot, add Cera Flava and squalane, be heated to 70 ~ 80 DEG C of temperature, 3 ~ 5 minutes heat time heating times; In heating process, add Folium olive powder, dimethyl sulfone while stirring in pot, trehalose while stirring family's heat extremely, stops heating in backward pot and adds glycyrrhizic acid dipotassium to stir well, and obtains outer plaster 2 mastic; In the time of 65 ~ 80 DEG C of outer plaster 2 mastic temperature, use while hot brush to brush, outer plaster 2 mastic are coated in to the outside of the internal layer plaster medicine cake that step 4) obtains, outer plaster 2 mastic coating zones cover and are greater than the coating zone of internal layer mastic; After outer plaster 2 is cooling and get final product; The present embodiment ectomesoderm plaster 2 and internal layer plaster 3 are taken and are applied into one and force on according to weight ratio 1:5; The outer thickness of plaster 2 and the thickness ratio of internal layer plaster 3 are 1:3 ~ 4; Folium olive powder adopts dry raw material Folium olive to pulverize 500 mesh sieves and obtains.
Clinical practice of the present invention is summarized as follows:
Be below the medicable disease of volume plaster of the present invention, and the Symptoms of disease.
Cervical spondylopathy: when cervical region stretches naturally, physiological camber weakens or disappears, and somebody's cervical region is partially askew, movable normal or slightly limited, musculi colli spasm, is dispersed in pressure pain point.Cervical region palpation is suffered between joint spinous process and can there be tenderness both sides, but much lighter, how without radiating pain.In addition, pressure head test and brachial plexus nerve distraction test feminine gender.
Sympathetic type of cervical spondylosis: often with the performance of Vertebro-basilar System blood supply insufficiency, as heavy in dizzy or dizzy, headache or migraine, head, occipitalia bitterly, not good enough, the hypomnesis of sleeping, difficult concentrating etc.The normal main suit of patient insobriety, has dizzy spells, and what have even occurs hypomnesis; Some patient also with feel sick, rare vomiting.Occasionally have because of the dizzy person of falling.Ophthalmic bloated, dry and astringent or many tear, vision change, blurring of vision; Tinnitus, ear block up, auditory dysesthesia; Foreign body in pharynx sense, xerostomia, vocal cords fatigue etc.; Sense of taste change etc.Nauseating even vomiting, abdominal distention, diarrhoea, dyspepsia, belch and foreign body in pharynx sense etc.Cardiopalmus, uncomfortable in chest, changes in heart rate, arrhythmia, blood pressure etc.Limbs are sent out cool to be afraid of cold, and also can have a side limbs hypohidrosis, head and neck, face or numb limbs and tense tendons.Above symptom often has obvious relation with cervical region activity, and seat or increase the weight of while standing alleviates when clinostatism or disappears.Cervical region activity is many, bow for a long time, obvious when before computer, the working time is long or tired, after having a rest, take a turn for the better.
Cervical spondylotic radiculopathy: numbness of the fingers, finger tip hyperesthesia and dermal sensation are gone down, numbness and pain, and its scope is consistent with the region that crest nerve is arranged, x-ray plain film can show that cervical curvature changes, vertebra saves the abnormal findings such as shakiness and bony spur formation, MRI checks can clearly show local pathological anatomy state, comprises outstanding and position and the degree of deviating from, spinal nerve root is got involved of vertebral pulp.
Cervical spondylotic myelopathy: numb limbs and tense tendons is unable, movable ineffective, have the sensation of stepping on Cotton Gossypii, kneecap spasm or ankle spasm while walking.Offside is taking sensory disturbance as main, sense of touch, thermo aesthesia and dysalgia; Movable unfavorable, walking shakiness, is unable to leave the bed, dyspnea, and extremity muscular tension increases, and muscular strength weakens, tendon hyperreflexia, superficial reflex weakens or disappears, the pathologic reflex positive.Patient has breast, waist zonesthesia.Clinical manifestation is early stage bilateral or single lower limb numbness, pain, stiffly shake, unable, tremble, difficulty in walking, bilateral upper limb is numb then, article are easily lost in grasp weakness.When above-mentioned symptom increases the weight of, can there be constipation, dysuria and urine retention or incontinence, or be unable to leave the bed, also can concurrent giddy, dim eyesight, dysphagia, the face abnormal sympathetic nerve symptom that waits of perspiring.
Esophagus compressive cervical spondylosis: be mainly in early days the abnormal sense of having any problem while swallowing hard food after sense and food metasternum (burn, twinge etc.), gradually and soft diet and liquid diet are swallowed in impact, dysphagia while facing upward neck, disappears while bending neck.
Vertebral artery type of cervical spondylosis: headache symptom, migraine, taking temples as acute, is jumping pain or twinge more.Labyrinthine symptom, is mainly the symptoms such as tinnitus, auditory dysesthesia and deafness.Vestibule symptom main manifestations is dizzy, hypomnesis.There is visual deterioration, blurred vision, diplopia, photis and of short duration blind etc. in visual disorder.Neurasthenia, how, insomnia forgetful with nearly thing and dreaminess phenomenon.Asophia, hoarse and lip feeling of numbness etc., can there is dysphonia in severe patient.Damping off when patient is in the time that a certain position head and neck rotates, prominent sense is dizzy, headache, and patient embraces head immediately, and two lower limb feel like jelly unable like shape out of control, fall immediately (seat) and be poured on ground.
Prolapse of lumbar intervertebral disc cardinal symptom: waist persistence dull pain, horizontal position alleviates, the aggravation of standing, lower limb radiating pain, radioactivity stimulation or feeling of numbness, creeping chill and intermittent claudication by waist to thigh and posterior leg.Waist is anteflexion, button Cobalt, lateral bending and limited in rotation.
Knee joint ankle joint cartilage injury: distribute unbalance or load of mechanical stress that what the present invention treated be mainly excessively causes the articular cartilage damage that cartilage wearing and tearing are feature.Early stage pain while be movable, even also there is pain when later rest, can feel the friction sound of articular surface sometimes.When scurrying and jumping, joint is clashed into and is produced pain, and joint motion is limited day by day obvious, until range of motion obviously reduces.
Be retarded by silt as the flesh and blood mobilization force of the feature bone inner high voltage extremely and thus taking bone angular vein, make that arteriovenous pressure reduction dwindles, the Oligemia of nutrient vessel, malnutrition can cause bone trabecula necrosis, osteocyte necrosis may be one of reason of bringing out primary disease.Initial stage, the slow person's gonalgia of onset is not serious, sustainability dull pain, and when temperature reduces, pain increases the weight of, relevant with climate change, come into play after rising morning, walking for a long time, and strenuous exercise or the sitting gonalgia that stands up while starting to walk is stiff, after slightly movable, take a turn for the better, upper and lower building difficulty, downstairs time, knee joint is felt like jelly, and easily falls down.Pain while crouching, stiff, when serious, joint aches distending pain, walks lamely, function of joint is limited, the most obvious to squat down, stretching the activity of bending has snap sound, the visible hydrarthrosis of some patients were, there are obvious tumefaction, tenderness phenomenon in part, merges rheumatism patient redness and swelling of joints, the lopsided synovial fluid inspection joint of getting involved and increases as synovial fluid amount can appear in the synovitis that occurs together.Typical case person is clear, sticky, cell number not high (<20 × 10/ liter), mostly is mononuclear cell.Visible cartilage or GUSUIPIAN granule, visible chondrocyte in cartilage fragment
The usage of a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis of the present invention, is used the clean pars affecta skin of hot towel, and uses medical 75% alcohol disinfecting pars affecta skin before using; Plaster of the present invention is baked to 55 ~ 70 DEG C, and after plaster is softening, docile is in pars affecta skin surface; After plaster is cooling, can strong bond pars affecta skin, and be difficult for dropping.Plaster is finished using and can be toasted heat posted and take the affected part of plaster, and plaster of the present invention is taken off.The usage and dosage of plaster of the present invention: a force on docile 14 days.Every note plaster is stopped using 1 day after finishing using, and square re-binding second is forced on, and two force on uses 30 days is a course for the treatment of; In 1 day that every note plaster is stopped using after finishing using, can clean pars affecta skin, then hot compress affected part 10 ~ 20 minutes, hot compress in a day 1 ~ 3 time, spreads at affected part to accelerate to infiltrate into subcutaneous plaster effective ingredient, thereby improves drug effect.Points for attention: plaster of the present invention child below 10 years old and anemia of pregnant woman's forbidding, women need avoid using menstrual period.
clinic diagnosis report
Taking most preferred embodiment 1 treats following disease respectively as treatment plaster.Curative effect judging standard: the improvement situation according to above-mentioned symptom is divided into curative effect healing, takes a turn for the better and do not heal, within the course for the treatment of described in the effective effect of aforementioned disease classification use, total effective rate is cure rate and improvement rate sum.After using continuously 5 ~ 6 courses for the treatment of of plaster for the treatment of cervical spondylosis lumbar spondylosis of the present invention, add up, statistical result is as shown in table 1:
Table 1 is the case statistics for the treatment of the plaster of cervical spondylosis lumbar spondylosis with the present invention
Total effective 1649 examples, recovery from illness 1556 examples, take in 5 ~ 6 courses for the treatment of total effective rate 90%, cure rate 85%.Above patient uses in 5 ~ 6 courses for the treatment of of plaster of the present invention all without anaphylaxis.
Applicant makes comparative example in order to strengthen contrast effect, the formula of comparative example and preparation method are with embodiment 1, but in comparative example, do not configure the outer plaster 2 in embodiment 1, there is no operating procedure 5 yet) in outer plaster 2 prepare and coating step, an operating procedure 1 ~ 4.Applicant gives subsides by the plaster of comparative example to above 1830 each patients of patient, please patient uses using after 5 ~ 6 courses for the treatment of of plaster of the embodiment of the present invention 1, and comparative example using method is with embodiment 1.One pastes and uses after 14 days, and after applicant's track record is found to have 10 patients to use 1 ~ 3 day in 1830 patients, gargalesthesia appears in affected part, in 10 3 routine patients occur itching pain, with red and swollen symptom, above transference cure after the plaster of the comparative example of stopping using.
The above, be only preferred embodiment of the present invention, is not the restriction of the present invention being made to other form, and any those skilled in the art may utilize the technology contents of above-mentioned announcement to be changed or be modified as the equivalent embodiment of equivalent variations.But every technical solution of the present invention content that do not depart from, any simple modification, equivalent variations and the remodeling above embodiment done according to technical spirit of the present invention, still belong to the protection domain of technical solution of the present invention.

Claims (10)

1. a plaster for the treatment of cervical spondylosis lumbar spondylosis, is characterized in that: comprise successively from top to bottom outer plaster (2), internal layer plaster (3) and carrier (1), the coated area of outer plaster (2) is greater than the coated area of internal layer plaster (3);
Internal layer plaster (3) is made up of the dry raw material of following weight portion: 5 ~ 10 parts of Os Draconis (calcined)s, 5 ~ 10 parts of Pheretimas, 5 ~ 10 parts of Scolopendras, 5 ~ 10 parts of Scorpios, 5 ~ 10 parts of Hirudos, 5 ~ 10 parts of Bombyx Batryticatus, shell 10 ~ 15 parts of Limaxs, 5 ~ 10 parts of Cordyceps, 5 ~ 10 parts of Olibanums, 5 ~ 10 parts of Myrrhas, 5 ~ 10 parts of Endoconcha Sepiaes, 1 ~ 3 part of Borneolum Syntheticum, 2 ~ 5 parts of Colophonium, 2 ~ 5 parts of succinums, 15 ~ 25 parts of Caulis Spatholobis, 10 ~ 20 parts of Caulis Polygoni Multiflori, 20 ~ 30 parts of Caulis Loniceraes, 10 ~ 20 parts of Radix Aconiti Preparatas, 10 ~ 20 parts of Herba Asaris, 10 ~ 20 parts of Radix Dipsacis, 10 ~ 20 parts of the Cortexs Eucommiae, 10 ~ 20 parts of Radix Aconiti Lateralis Preparatas, 10 ~ 20 parts of Flos Magnoliaes, 10 ~ 20 parts of Radix cocculi laurifoliis, 10 ~ 20 parts of Radix Angelicae Pubescentiss, 10 ~ 20 parts of Herba Rosmarini Officinaliss, 10 ~ 20 parts of Ramulus Sambuci Williamsii, 5 ~ 10 parts of Benzoinumes, 5 ~ 10 parts of Sanguis Draxonis, 10 ~ 20 parts of Radix Angelicae Sinensis, 10 ~ 20 parts of Cortex Cinnamomis, 5 ~ 10 parts, Fructus Capsici, 10 ~ 20 parts of Herba Pelargonii Graveolentiss, 20 ~ 30 parts of Coriolous Dersicolor (Fr.) Quel, 40 ~ 50 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 20 ~ 30 parts of Grifola frondosa, 40 ~ 50 parts of Radix Scutellariaes, 40 ~ 50 parts of Radix Et Rhizoma Rhei, 40 ~ 50 parts of the Radixs Angelicae Dahuricae, 40 ~ 50 parts of Geckos, 20 ~ 30 parts, Semen Persicae, 40 ~ 50 parts of Semen Ziziphi Spinosaes, 20 ~ 30 parts of Fructus Caricae, 20 ~ 30 parts, Fructus Pruni pseudocerasi, 20 ~ 30 parts of Fructus Hippophaes, 30 ~ 40 parts of Semen Aesculies, 20 ~ 30 parts of the Radixs Astragali, 20 ~ 30 parts of Folium Ginkgos, 40 ~ 50 parts of Galla Chinensiss, 20 ~ 30 parts of Radix Rhodiolaes, 20 ~ 30 parts of Stigma Crocis, 20 ~ 30 parts of Cortex Moutans, 20 ~ 30 parts, Rhizoma Gastrodiae, 20 ~ 30 parts of Rhizoma Polygoni Cuspidati, 20 ~ 30 parts of Rhizoma Belamcandae, 20 ~ 30 parts of Radix Bupleuri, 30 ~ 40 parts of Radix orixae japonicaes, 20 ~ 30 parts of Flos Albiziaes, 20 ~ 30 parts of Flos Rosae Chinensiss, 20 ~ 30 parts of Herb Gynostemmae Pentaphylli, 20 ~ 30 parts of Radix gynurae segeti, 20 ~ 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 ~ 15 parts of Radix Scrophulariaes, 10 ~ 15 parts of Radix Sophorae Flavescentiss, 30 ~ 40 parts of Cortex Phellodendris, 500 ~ 1000 parts of Plumbum preparatiums, 1000 ~ 2000 parts of Oleum sesami,
Outer plaster (2) is made up of the dry raw material of following weight portion: 0.5 ~ 2 part of glycyrrhizic acid dipotassium, 1 ~ 5 part of trehalose, 1 ~ 10 part, Folium olive, 1 ~ 10 part, Cera Flava, 1 ~ 10 part of squalane, 1 ~ 5 part of dimethyl sulfone.
2. a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis according to claim 1, is characterized in that:
Internal layer plaster (3) is made up of the dry raw material of following weight portion: 7 ~ 9 parts of Os Draconis (calcined)s, 7 ~ 9 parts of Pheretimas, 7 ~ 9 parts of Scolopendras, 7 ~ 9 parts of Scorpios, 7 ~ 9 parts of Hirudos, 7 ~ 9 parts of Bombyx Batryticatus, shell 12 ~ 14 parts of Limaxs, 7 ~ 9 parts of Cordyceps, 7 ~ 9 parts of Olibanums, 7 ~ 9 parts of Myrrhas, 7 ~ 9 parts of Endoconcha Sepiaes, 1 ~ 3 part of Borneolum Syntheticum, 2 ~ 5 parts of Colophonium, 2 ~ 5 parts of succinums, 15 ~ 25 parts of Caulis Spatholobis, 13 ~ 17 parts of Caulis Polygoni Multiflori, 22 ~ 26 parts of Caulis Loniceraes, 13 ~ 17 parts of Radix Aconiti Preparatas, 13 ~ 17 parts of Herba Asaris, 13 ~ 17 parts of Radix Dipsacis, 13 ~ 17 parts of the Cortexs Eucommiae, 13 ~ 17 parts of Radix Aconiti Lateralis Preparatas, 13 ~ 17 parts of Flos Magnoliaes, 13 ~ 17 parts of Radix cocculi laurifoliis, 13 ~ 17 parts of Radix Angelicae Pubescentiss, 13 ~ 17 parts of Herba Rosmarini Officinaliss, 13 ~ 17 parts of Ramulus Sambuci Williamsii, 7 ~ 9 parts of Benzoinumes, 7 ~ 9 parts of Sanguis Draxonis, 13 ~ 17 parts of Radix Angelicae Sinensis, 13 ~ 17 parts of Cortex Cinnamomis, 7 ~ 9 parts, Fructus Capsici, 13 ~ 17 parts of Herba Pelargonii Graveolentiss, 22 ~ 26 parts of Coriolous Dersicolor (Fr.) Quel, 45 ~ 48 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 22 ~ 26 parts of Grifola frondosa, 45 ~ 48 parts of Radix Scutellariaes, 45 ~ 48 parts of Radix Et Rhizoma Rhei, 45 ~ 48 parts of the Radixs Angelicae Dahuricae, 45 ~ 48 parts of Geckos, 22 ~ 26 parts, Semen Persicae, 45 ~ 48 parts of Semen Ziziphi Spinosaes, 22 ~ 26 parts of Fructus Caricae, 22 ~ 26 parts, Fructus Pruni pseudocerasi, 22 ~ 26 parts of Fructus Hippophaes, 35 ~ 38 parts of Semen Aesculies, 22 ~ 26 parts of the Radixs Astragali, 22 ~ 26 parts of Folium Ginkgos, 45 ~ 48 parts of Galla Chinensiss, 22 ~ 26 parts of Radix Rhodiolaes, 22 ~ 26 parts of Stigma Crocis, 22 ~ 26 parts of Cortex Moutans, 22 ~ 26 parts, Rhizoma Gastrodiae, 22 ~ 26 parts of Rhizoma Polygoni Cuspidati, 22 ~ 26 parts of Rhizoma Belamcandae, 22 ~ 26 parts of Radix Bupleuri, 35 ~ 38 parts of Radix orixae japonicaes, 22 ~ 26 parts of Flos Albiziaes, 22 ~ 26 parts of Flos Rosae Chinensiss, 22 ~ 26 parts of Herb Gynostemmae Pentaphylli, 22 ~ 26 parts of Radix gynurae segeti, 22 ~ 26 parts of the Rhizoma Atractylodis Macrocephalaes, 12 ~ 14 parts of Radix Scrophulariaes, 12 ~ 14 parts of Radix Sophorae Flavescentiss, 35 ~ 38 parts of Cortex Phellodendris, 500 ~ 1000 parts of Plumbum preparatiums, 1000 ~ 2000 parts of Oleum sesami,
Outer plaster (2) is made up of the dry raw material of following weight portion: 0.7 ~ 1.5 part of glycyrrhizic acid dipotassium, 2 ~ 4 parts of trehaloses, 2 ~ 6 parts, Folium olive, 4 ~ 9 parts, Cera Flava, 2 ~ 7 parts of squalanes, 2 ~ 4 parts of dimethyl sulfones.
3. a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis according to claim 1, is characterized in that:
Described internal layer plaster (3) is made up of the dry raw material of following weight portion: 7 parts of Os Draconis (calcined)s, 8 parts of Pheretimas, 7 parts of Scolopendras, 7 parts of Scorpios, 8 parts of Hirudos, 9 parts of Bombyx Batryticatus, shell 13 parts of Limaxs, 9 parts of Cordyceps, 8 parts of Olibanums, 7 parts of Myrrhas, 8 parts of Endoconcha Sepiaes, 1.5 parts of Borneolum Syntheticums, 2 parts of Colophonium, 3 parts of succinums, 18 parts of Caulis Spatholobis, 14 parts of Caulis Polygoni Multiflori, 23 parts of Caulis Loniceraes, 15 parts of Radix Aconiti Preparatas, 16 parts of Herba Asaris, 14 parts of Radix Dipsacis, 14 parts of the Cortexs Eucommiae, 15 parts of Radix Aconiti Lateralis Preparatas, 14 parts of Flos Magnoliaes, 16 parts of Radix cocculi laurifoliis, 14 parts of Radix Angelicae Pubescentiss, 17 parts of Herba Rosmarini Officinaliss, 14 parts of Ramulus Sambuci Williamsii, 7 parts of Benzoinumes, 7 parts of Sanguis Draxonis, 16 parts of Radix Angelicae Sinensis, 14 parts of Cortex Cinnamomis, 7 parts, Fructus Capsici, 16 parts of Herba Pelargonii Graveolentiss, 23 parts of Coriolous Dersicolor (Fr.) Quel, 47 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 25 parts of Grifola frondosa, 47 parts of Radix Scutellariaes, 45 parts of Radix Et Rhizoma Rhei, 45 parts of the Radixs Angelicae Dahuricae, 45 parts of Geckos, 23 parts, Semen Persicae, 487 parts of Semen Ziziphi Spinosaes, 23 parts of Fructus Caricae, 25 parts, Fructus Pruni pseudocerasi, 25 parts of Fructus Hippophaes, 37 parts of Semen Aesculies, 24 parts of the Radixs Astragali, 24 parts of Folium Ginkgos, 45 parts of Galla Chinensiss, 25 parts of Radix Rhodiolaes, 25 parts of Stigma Crocis, 23 parts of Cortex Moutans, 23 parts, Rhizoma Gastrodiae, 24 parts of Rhizoma Polygoni Cuspidati, 24 parts of Rhizoma Belamcandae, 24 parts of Radix Bupleuri, 38 parts of Radix orixae japonicaes, 24 parts of Flos Albiziaes, 23 parts of Flos Rosae Chinensiss, 23 parts of Herb Gynostemmae Pentaphylli, 25 parts of Radix gynurae segeti, 23 parts of the Rhizoma Atractylodis Macrocephalaes, 13 parts of Radix Scrophulariaes, 14 parts of Radix Sophorae Flavescentiss, 37 parts of Cortex Phellodendris, 500 ~ 1000 parts of Plumbum preparatiums, 1000 ~ 2000 parts of Oleum sesami,
Described outer plaster (2) is made up of the dry raw material of following weight portion: 0.8 part of glycyrrhizic acid dipotassium, 3 parts of trehaloses, 4.5 parts, Folium olive, 7 parts, Cera Flava, 6 parts of squalanes, 2.5 parts of dimethyl sulfones.
4. according to a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis described in claim 1,2 or 3; it is characterized in that: on described carrier (1), be bonded with protecting film (4); protecting film (4) is bonded in the carrier surface relative with internal layer plaster (3) bonding plane; protecting film (4) shape is identical with carrier (1) shape; carrier (1) adopts pure cotton fabric or non-woven fabrics material, and protecting film (4) is plastic material or paper.
5. according to a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis described in claim 1,2 or 3, it is characterized in that: described outer plaster (2) and internal layer plaster (3) are according to weight ratio 1:1 ~ 8.
6. according to a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis described in claim 1,2 or 3, it is characterized in that: the thickness ratio of the thickness of described outer plaster (2) and internal layer plaster (3) is 1:2 ~ 5.
7. a preparation method for the treatment of the plaster of cervical spondylosis lumbar spondylosis, is characterized in that, adopts following steps:
1) by 20 ~ 30 parts of dry raw material Coriolous Dersicolor (Fr.) Quel, 40 ~ 50 parts of Hericium erinaceus (Bull. Ex Fr.) Pers., 20 ~ 30 parts of Grifola frondosa, 40 ~ 50 parts of Radix Scutellariaes, 40 ~ 50 parts of Radix Et Rhizoma Rhei, 40 ~ 50 parts of the Radixs Angelicae Dahuricae, 40 ~ 50 parts of Geckos, 20 ~ 30 parts, Semen Persicae, 40 ~ 50 parts of Semen Ziziphi Spinosaes, 20 ~ 30 parts of Fructus Caricae, 20 ~ 30 parts, Fructus Pruni pseudocerasi, 20 ~ 30 parts of Fructus Hippophaes, 30 ~ 40 parts of Semen Aesculies, 20 ~ 30 parts of the Radixs Astragali, 20 ~ 30 parts of Folium Ginkgos, 40 ~ 50 parts of Galla Chinensiss, 20 ~ 30 parts of Radix Rhodiolaes, 20 ~ 30 parts of Stigma Crocis, 20 ~ 30 parts of Cortex Moutans, 20 ~ 30 parts, Rhizoma Gastrodiae, 20 ~ 30 parts of Rhizoma Polygoni Cuspidati, 20 ~ 30 parts of Rhizoma Belamcandae, 20 ~ 30 parts of Radix Bupleuri, 30 ~ 40 parts of Radix orixae japonicaes, 20 ~ 30 parts of Flos Albiziaes, 20 ~ 30 parts of Flos Rosae Chinensiss, 20 ~ 30 parts of Herb Gynostemmae Pentaphylli, 20 ~ 30 parts of Radix gynurae segeti, 20 ~ 30 parts of the Rhizoma Atractylodis Macrocephalaes, 10 ~ 15 parts of Radix Scrophulariaes, 10 ~ 15 parts of Radix Sophorae Flavescentiss, 30 ~ 40 parts of Cortex Phellodendris were pulverized respectively 10 ~ 20 mesh sieves and obtained medical material granules, medical material granule were put under the mixed liquor room temperature of 2500 ~ 5000 parts of ethanol and water and were soaked 30 ~ 60 days, soaked to finish to filter medical material granule and obtain lixiviating solution, and dry lixiviating solution obtains lixiviate powder,
2) by 15 ~ 25 parts of dry raw material Caulis Spatholobis, 10 ~ 20 parts of Caulis Polygoni Multiflori, 20 ~ 30 parts of Caulis Loniceraes, 10 ~ 20 parts of Radix Aconiti Preparatas, 10 ~ 20 parts of Herba Asaris, 10 ~ 20 parts of Radix Dipsacis, 10 ~ 20 parts of the Cortexs Eucommiae, 10 ~ 20 parts of Radix Aconiti Lateralis Preparatas, 10 ~ 20 parts of Flos Magnoliaes, 10 ~ 20 parts of Radix cocculi laurifoliis, 10 ~ 20 parts of Radix Angelicae Pubescentiss, 10 ~ 20 parts of Herba Rosmarini Officinaliss, 10 ~ 20 parts of Ramulus Sambuci Williamsii, 5 ~ 10 parts of Benzoinumes, 5 ~ 10 parts of Sanguis Draxonis, 10 ~ 20 parts of Radix Angelicae Sinensis, 10 ~ 20 parts of Cortex Cinnamomis, 10 ~ 20 parts of medical material granules of pulverizing respectively 30 ~ 40 mesh sieves acquisitions of 5 ~ 10 parts, Fructus Capsici and Herba Pelargonii Graveolentis are put into Oleum sesami, soak at room temperature 60 ~ 90 days, remove by filter and obtain medicine oil,
3) will after 5 ~ 10 parts of Os Draconis (calcined)s, 5 ~ 10 parts of Pheretimas, 5 ~ 10 parts of Scolopendras, 5 ~ 10 parts of Scorpios, 5 ~ 10 parts of Hirudos, 5 ~ 10 parts of Bombyx Batryticatus, 10 ~ 15 parts of the Limaxs of shelling, 5 ~ 10 parts of Cordyceps, 5 ~ 10 parts of Olibanums, 5 ~ 10 parts of Myrrhas, 5 ~ 10 parts of Endoconcha Sepiaes, 1 ~ 3 part of Borneolum Syntheticum, 2 ~ 5 parts of Colophonium, 2 ~ 5 parts of pulverizing of succinum, be mixed, cross 200 ~ 300 mesh sieves and obtain medicinal powder;
4) in pot, pour step 2 into) the middle medicine oil obtaining, be heated to 70 ~ 100 DEG C of oil temperatures, put into Plumbum preparatium powder, by step 2) in obtain lixiviate powder pour in pot, endure while becoming wire drawing shape to medicine oil, pour the medicinal powder obtaining in step 3) into, after stirring evenly, be heated at 100 ~ 130 DEG C and keep 2 ~ 5 minutes, obtain internal layer plaster mastic; Cease fire and treat that mastic temperature is down to 60 ~ 70 DEG C, taking internal layer plaster mastic, to be coated on carrier (1) upper, is pressed into internal layer plaster medicine cake;
5) to adding 1 ~ 10 part, Cera Flava and 1 ~ 5 part of squalane in pot, being heated to 70 ~ 80 DEG C of temperature, 1 ~ 5 minute heat time heating time; In heating process, while stirring to add in pot 1 ~ 5 part, 1 ~ 5 part, Folium olive powder, 1 ~ 5 part of dimethyl sulfone, trehalose while stirring family's heat extremely, stop heating in backward pot and add 0.5 ~ 2 part of glycyrrhizic acid dipotassium to stir well, obtain outer plaster (2) mastic; In the time of 65 ~ 80 DEG C of outer plaster (2) mastic temperature, while hot outer plaster (2) mastic is coated in to the outside of the internal layer plaster medicine cake that step 4) obtains, outer plaster (2) mastic coating zone covers and is greater than the coating zone of internal layer mastic; The thickness of outer plaster (2) and the thickness ratio of internal layer plaster (3) are 1:2 ~ 5; After outer plaster (2) is cooling and get final product.
8. the preparation method of a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis according to claim 5, is characterized in that: the ethanol described in step 1) and the mixed liquor of water adopt ethanol and water to mix according to weight ratio 1 ~ 2:1.
9. the preparation method of a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis according to claim 5, is characterized in that: the method for the dry lixiviating solution described in step 1) be under normal pressure to lixiviating solution constant temperature drying, 100 DEG C of bake out temperatures, obtain lixiviate powder; Or the method for described dry lixiviating solution is that the ethanol of under normal pressure, lixiviating solution heated at constant temperature to 79 ~ 80 DEG C being removed in lixiviating solution obtains concentrated lixiviating solution, concentrated frozen lixiviating solution is carried out to vacuum lyophilization and remove moisture acquisition lixiviate powder.
10. the preparation method of a kind of plaster for the treatment of cervical spondylosis lumbar spondylosis according to claim 5, is characterized in that: described in step 5), Folium olive powder adopts dry raw material Folium olive was pulverized to 500 ~ 600 mesh sieves acquisitions.
CN201410399201.3A 2014-08-14 2014-08-14 Plaster for treating cervical spondylosis and lumbar spondylosis Pending CN104116936A (en)

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CN104491259A (en) * 2014-12-03 2015-04-08 徐学新 Waterproof bonesetting cream formula and preparation method thereof
CN105998420A (en) * 2016-06-29 2016-10-12 邱定武 Medicine cake for treating cervical spondylosis and preparing method thereof
CN108478932A (en) * 2018-03-29 2018-09-04 缔道(天津)生物科技有限责任公司 Multifunction infrared mild moxibustion physiotherapy note product and preparation method thereof

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CN108478932A (en) * 2018-03-29 2018-09-04 缔道(天津)生物科技有限责任公司 Multifunction infrared mild moxibustion physiotherapy note product and preparation method thereof

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