CN105688040A - Plaster for treating cervical spondylotic radiculopathy - Google Patents
Plaster for treating cervical spondylotic radiculopathy Download PDFInfo
- Publication number
- CN105688040A CN105688040A CN201610095639.1A CN201610095639A CN105688040A CN 105688040 A CN105688040 A CN 105688040A CN 201610095639 A CN201610095639 A CN 201610095639A CN 105688040 A CN105688040 A CN 105688040A
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- parts
- plaster
- rhizoma
- filtrate
- spondylotic radiculopathy
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Abstract
The invention discloses a plaster for treating cervical spondylotic radiculopathy. The plaster for treating cervical spondylotic radiculopathy is mainly prepared from, by weight, 8-14 parts of Radix Puerariae, 6-9 parts of Herba Lycopodii, 9-15 parts of Rhizoma Dioscoreae Nipponicae, 5-10 parts of Rhizoma et Radix Notopterygii, 4-11 parts of Rhizoma Wenyujin Concisum, 7-13 parts of Zaocys, 6-15 parts of Herba Pyrolae, 6-9 parts of Ramulus Uncariae Cum Uncis, 1-5 parts of Toddalia asiatua (L.) Lam. and 1-9 parts of Squama Manis. The plaster for treating cervical spondylotic radiculopathy is capable of activating blood circulation to stimulate menstrual flow and relieving pain to dredge collaterals and is remarkably effective in treatment of cervical spondylotic radiculopathy and complications thereof.
Description
Divisional application, original applying number 2014101736898, applying date 2014.04.28, a kind of plaster treating cervical spondylotic radiculopathy of title and preparation method thereof。
Technical field
The invention discloses a kind of plaster treating cervical spondylotic radiculopathy and preparation method thereof, its dosage form is unguentum, the invention belongs to traditional Chinese medicine field。
Background technology
Cervical spondylosis, also known as cervical spine syndrome, is the general name of osteoarthritis of cervical spine, proliferative cervical spondylosis, cervical syndrome, Cervical disc extrusion, is a kind of illness changing into basis with degeneration pathology。Strain for a long time mainly due to cervical vertebra, hyperosteogeny, or prolapse of intervertebral disc, ligament thicken, and causes cervical vertebra spinal cord, nerve root or vertebral artery pressurized, a series of handicapped clinical syndrome occurs。Show as intervertebral disc degradation itself and insecondary a series of pathological change thereof, as vertebra saves unstability, loosens；Nucleus pulposus or deviate from；Bony spur is formed；The plump spinal canal stenosis etc. with secondary of ligament, stimulates or has oppressed the tissues such as the nerve root of vicinity, spinal cord, vertebral artery and cervical region sympathetic nerve, causing series of symptoms and sign。
Cervical spondylotic radiculopathy is because of caused by unilateral or bilateral spinal nerve root irriate or pressurized, it shows as the sensation consistent with spinal nerve root areal area, motion and reflecting barrier, primary disease is more common, various non-operative treatment targetedly all have obvious curative effect, wherein especially continue (or be interrupted) traction, neck circumference braking with head and neck and to correct bad position effective。
The clinical symptoms of cervical spondylosis is complex。Mainly have nape pain, upper myasthenia of limbs, finger is numb, lower limb are weak, difficulty in walking, dizziness, Nausea and vomiting, even blurred vision, tachycardia and dysphagia etc.。The clinical symptoms of cervical spondylosis has certain relation with diseased region, tissue involved and individual variation。
The clinical manifestation of cervical spondylotic radiculopathy: 1. neck symptom: the reason depending on causing root pressurized is different and weight differs。Main because of person caused by Nucleus pulposus, many owing to local hole nervi vertebralis is directly stimulated attention formula position with obvious cervical region pain, paravertebral muscles tenderness and cervical region, cervical spine or interspinal direct tenderness or kowtow pain and mostly be positive, and these performances are obvious with acute stage especially。As being pure uncovertebral joint regression and caused by hyperosteogeny person, then neck symptom is relatively slight, even can without special discovery。2. a property pain: the most common, its scope is consistent with the spinal nerve root distributed areas of vertebra joint of getting involved。What accompany with root pain is other sensory disturbances of this nerve root areal area, wherein goes down etc. as common with numbness of the fingers, finger tip hyperesthesia and dermal sensation。3. a property muscular strength obstacle: former root elder generation pressurized person is substantially, early stage hypermyotonia, but quickly namely weakens and amyotrophy occur。Its scope of getting involved also is limited only to the flesh group that this spinal nerve root is arranged。It is obvious at hand with large and small thenar and interosseus。4. tendon reflex changes: the reflex arc that spinal nerve root of namely getting involved participates in occurs abnormal。Early stage is active, and the intermediary and later stages then go down or disappear, should compared with offside during inspection。Simple root is got involved should not pathologic reflex, as with pathologic reflex, then it represents that spinal cord is got involved simultaneously。
5. sign: the tractive test of all increase spinal nerve root tension force is mostly positive, especially acute stage and later root pressurized are main person。Cervical vertebra squeeze test positive is more common in and is deviate from based on Nucleus pulposus, vertebral pulp and case that vertebra joint is unstable, and because person caused by hook vertebra hypertrophy is mostly the weak positive, because of person caused by Intraspinal Occupying Lesion, is mostly feminine gender。
In the invention of existing treatment cervical spondylotic radiculopathy, Authorization Notice No. Authorization Notice No. CN102526406B(application number 201210039492.6) Chinese patent disclose a kind of Chinese medicinal plaster treating cervical spondylotic radiculopathy and preparation method thereof: Radix Astragali 20-40 part, Radix Angelicae Sinensis 10-25 part, Herba Epimedii 15-30 part, Colla cornus cervi 5-25 part, Radix Paeoniae Rubra 6-20 part, Ramulus Cinnamomi 6-20 part, Sanguis Draxonis 3-20 part, Herba Lycopodii 6-20 part, Semen Sinapis 6-20 part, Radix Notoginseng 6-20 part, Flos Carthami 6-20 part, Olibanum 6-20 part, Borneolum Syntheticum 3-13 part。Authorization Notice No. CN101912539B(application number 201010257525.5) Chinese patent disclose a kind of for Chinese medicine composition treating cervical spondylotic radiculopathy and preparation method thereof, formula and part by weight be A, weigh 10-50 weight portion Radix Angelicae Sinensis, 10-50 weight portion Rhizoma Chuanxiong and 6-35 weight portion Cortex Cinnamomi, soak after mixing 1-3 hour, then distillating extracting oil at temperature 98-100 DEG C, the volatile oil beta-cyclodextrin inclusion compound of collection；Stir 1-3 hour at temperature 50-60 DEG C, place cooling, after cold drying, be ground into fine powder；Distillation remaining aqueous solution is stand-by with medicinal residues；B, respectively 10-50 weight portion Radix Notoginseng and 10-50 weight portion Rhizoma Gastrodiae powder are broken into fine powder, then they are mixed, add water immersion 1-3 hour, then decoct 1-2 hour, filter after cooling and obtain filtrate and medicinal residues, these medicinal residues with in step A) medicinal residues that obtain merge, boiling 1-3 time after mixing with 10-50 weight portion Flos Carthami again, each 0.5-3 hour, filter, this merging filtrate and the filtrate being previously obtained, step A) the distillation remaining aqueous solution that obtains merges, carry out concentrating under reduced pressure again until at temperature 50-60 DEG C the clear paste of relative density 1.10-1.30, then drying under reduced pressure, it is ground into fine powder, add 3-16 weight portion artificial Calculus Bovis, step A) obtain Benexate Hydrochloride and dextrin, mix homogeneously。
Summary of the invention
For existing current treatment status, an object of the present invention is in that to provide a kind of plaster treating cervical spondylotic radiculopathy, the Chinese medicine composition not only with the present invention has blood circulation promoting and blood stasis dispelling, the sensible pain relieving of warming the meridian, can be additionally used in cervical spondylotic radiculopathy syndrome of static blood blocking collaterals, disease sees that neck and shoulder part is stiff, pain, and ipsilateral upper limb alters pain etc.。
The preparation method that another object of the present invention is just to provide the plaster of above-mentioned treatment cervical spondylotic radiculopathy。
The above-mentioned purpose of the present invention is achieved through the following technical solutions:
A kind of plaster treating cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion to be prepared from: Radix Puerariae 8-14 part, Herba Lycopodii 6-9 part, Rhizoma Dioscoreae Nipponicae 9-15 part, Rhizoma Et Radix Notopterygii 5-10 part, Rhizoma Wenyujin Concisum 4-11 part, Zaocys 7-13 part, Herba Pyrolae 6-15 part, Ramulus Uncariae Cum Uncis 6-9 part, Sedum aizoon L. 1-5 part, Squama Manis 1-9 part。
The plaster of above-mentioned treatment cervical spondylotic radiculopathy, preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Radix Puerariae 10-12 part, Herba Lycopodii 7-8 part, Rhizoma Dioscoreae Nipponicae 11-13 part, Rhizoma Et Radix Notopterygii 6-8 part, Rhizoma Wenyujin Concisum 6-9 part, Zaocys 8-10 part, Herba Pyrolae 10-12 part, Ramulus Uncariae Cum Uncis 7-8 part, Sedum aizoon L. 2-4 part, Squama Manis 4-6 part。
The plaster of the above treatment cervical spondylotic radiculopathy, more preferably preferred scheme, takes off the primary raw material stating weight proportion and is prepared from: Radix Puerariae 11 parts, Herba Lycopodii 7.5 parts, Rhizoma Dioscoreae Nipponicae 12 parts, Rhizoma Et Radix Notopterygii 7 parts, Rhizoma Wenyujin Concisum 8 parts, Zaocys 9 parts, Herba Pyrolae 11 parts, Ramulus Uncariae Cum Uncis 7.5 parts, Sedum aizoon L. 3 parts, Squama Manis 5 parts。
Preparation method according to the above plaster of arbitrary described treatment cervical spondylotic radiculopathy, step is as follows:
1. being placed in non iron container by Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and stands 1-10 days, filters, obtains filtrate and filtering residue is standby；
2. step 1. middle gained filtering residue adds water, and the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 30-50 minute, filters to get filtrate；
3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 6-12 hour, filter, filtrate purifies again by the way of distillation, obtains distillate standby；
4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C-80 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 1-10g to spread upon in adhesive plaster or other substrate, make plaster。
According to above-mentioned preparation method, it is preferred that scheme is in that: 1. step stands 3-8 days (preferably 5 days)。
According to above-mentioned preparation method, it is preferred that scheme is in that: 2. step decocts to 35-45 minute (preferably 40 minutes)。
According to above-mentioned preparation method, it is preferred that scheme is in that: 3. step stands 7-10 hour (preferably 9 hours)。
According to above-mentioned preparation method, it is preferred that scheme is in that: 4. step is closed fire and be cooled to 65 DEG C-75 DEG C (preferably 70 DEG C)。
According to above-mentioned preparation method, it is preferred that scheme is in that: the weight ratio of step 4. vegetable oil, Colophonium, white vaseline and distillate is 0.8:1.5:1.5:0.8。
The application when the medicine of cervical spondylotic myelopathy, cervical muscle myelopathy is treated in preparation of the plaster of the treatment cervical spondylotic radiculopathy according to above any one。
Best using method: for the therapeutic effect making the present invention reach the best, plaster is directly affixed on uncomfortable cervical vertebra place, gently seals about 1 minute with palm after patch, and patch is worn 12 hours, and every day 1 time, 10 days is a course for the treatment of。
A kind of plaster treating cervical spondylotic radiculopathy, the pharmacological effect of each raw material is respectively as follows:
Radix Puerariae: sweet in the mouth, pungent, cool in nature。Return spleen, stomach warp。Effect: expelling pathogenic factors from muscles for reducing heat, promotes the production of body fluid, rash, yang invigorating antidiarrheal。Curing mainly: fever caused by exogenous pathogens is had a headache, stiff nape and back is thirsty, quenches one's thirst, measles without adequate eruption, hematodiarrhoea。
Herba Lycopodii: Herba Lycopodii, stolon is in thin cylindrical, and slightly curved song, length, up to 2m, diameter 1～3mm, has yellow-white radicula under it。Erect stern makes two dichotomies。On Ye Misheng stem, helical arrangement, shrinkage bends, linear or aciculiform, long 3～5mm, and yellow green is to fallow, without hair, tip aristiform, Quan Yuan, easily cataclasm。Matter is soft, and section skin zone is light yellow, woody part off-white color。Odorless, lightly seasoned。Toil temperature, enters Liver Channel。Expelling wind and cold. dehumidifying detumescence, relaxing muscles and tendons and activating QI and blood in the collateral。For anemofrigid-damp arthralgia, muscle arteries and veins contracture pain carbuncle。External is controlled osteopatia sprain and is swollen and ache。
Rhizoma Dioscoreae Nipponicae: return liver, kidney, lung meridian, warm in nature, sweet in the mouth, hardship。Relaxing muscles and tendons to promote blood circulation, relieving cough and resolving phlegm, wind-expelling pain-stopping。For lumbago and skelalgia, rheumatalgia, rheumatic arthritis, muscles and bones numbness, Kaschin-Beck disease, traumatic injury, sprain one's back, cough pant, tracheitis, bronchitis。
Rhizoma Et Radix Notopterygii: acrid in the mouth, hardship, warm in nature。Return bladder, kidney channel。Effect: cold expelling, dispels the wind, dehumidifying, pain relieving。Cure mainly: anemofrigid cold is had a headache, rheumatic arthralgia, aching pain in shoulder and back。
Rhizoma Wenyujin Concisum: acrid in the mouth, hardship, warm in nature。Return liver, spleen channel。Effect: removing blood stasis circulation of qi promoting, inducing menstruation to relieve menalgia。Cure mainly: amenorrhea due to stagnation of blood, menalgia, breast side of body twinge, rheumatic arthralgia, take on arm pain, injury from falling down。
Zaocys: sweet in the mouth, property is put down。Return Liver Channel。Effect: dispel the wind, dredging collateral, relieving convulsion。Cure mainly: rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil。
Herba Pyrolae: sweet in the mouth, hardship, warm in nature。Return liver, kidney channel。Effect: wind-damp dispelling, bone and muscle strengthening, hemostasis。Cure mainly: rheumatic arthralgia, weakness of the waist and knees, menorrhagia, chronic cough due to asthenia of viscera。
Ramulus Uncariae Cum Uncis: Ramulus Uncariae Cum Uncis sweet in the mouth, micro-hardship, cold nature；Return liver, pericardium channel；Matter heavily fortified point is dived and is dropped, and has heat clearing away suppressing the hyperactive liver, effect of relieving spasm by subduing liver-wind, cures mainly liver-fire superinverse headache conjunctival congestion, and excessive rising of liver-YANG is had a dizzy spell, intenseness of heat wind symptom infantile convulsion, infantile convulsion, night cry, eclamposia, paralysis due to windstroke, and podomere contraction is anxious。
Sedum aizoon L.: the upright draft of perennial root is high about 15 centimetres。Root length cone。Basal leaf has long handle, light green micro-strip blush, and the wealthy heart of blade or sub-circular, long 1～3 centimetre, wide 2～4.8 centimetres, there is shallow round cognate at edge。Spending single leave axil, rose-pink color bands is yellow。Capsule。[nature and flavor] pungent fiber crops, temperature。[function cures mainly] promoting the flow of QI in the collateral by warming the meridian, stopping bleeding and knitting the fractured bone。External is controlled open fracture, is controlled traumatic hemorrhage。
Squama Manis: salty in the mouth, cold nature。Return liver, stomach warp。Effect: stimulating milk secretion of stimulating the menstrual flow, detumescence and apocenosis, searches wind and removing obstruction in channels。Cure mainly: amenorrhea abdominal mass, galactostasis, carbuncle sore tumefacting virus, arthralgia, numbness contracture。
Colophonium, vegetable oil, white vaseline are excipient, play the effect of mediation figuration。
Plaster, is the big dosage form-ball of Chinese medicine five, scattered, one of cream, pellet, soup。Ancient doctor's speech is said: " plaster can be cured the disease, not different from decoction, does in the proper way with it, and it rings vertical answering。" prescription of the present invention all selects pungent perfume (or spice) to walk to go here and there extremely strong tying-in medicine, medicine directly infiltrates through skin, by interior transmission from one channel to another network, plays disperse blood stasis and dredge collateral, the effect that pain relieving is stimulated the menstrual flow。
Detailed description of the invention
Describe technical scheme in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction。
Embodiment 1 one kinds treats the plaster of cervical spondylotic radiculopathy, takes off the primary raw material stating weight proportion and is prepared from (every part takes 15g): Radix Puerariae 8 parts, Herba Lycopodii 6 parts, Rhizoma Dioscoreae Nipponicae 9 parts, Rhizoma Et Radix Notopterygii 5 parts, Rhizoma Wenyujin Concisum 4 parts, Zaocys 7 parts, Herba Pyrolae 6 parts, Ramulus Uncariae Cum Uncis 6 parts, Sedum aizoon L. 1 part, Squama Manis 1 part。
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. being placed in non iron container by Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and stands 1 day, filters, obtains filtrate and filtering residue is standby；
2. step 1. middle gained filtering residue adds water, and the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 30 minutes, filters to get filtrate；
3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 6 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby；
4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 1g to spread upon in adhesive plaster or other substrate, make plaster。
Typical case one poplar XX, man, 40 years old, Jinan, Shandong Province personage, the workman of certain factory。Nearest half a year cervical region pain, paravertebral muscles tenderness, and lower limb have feeling of numbness, stiff shake, walk that it is unable not have, and think it is that work is tired out at the beginning, do not take notice of very much yet, but in nearest one month, cervical vertebra pain is severe, directly affect sleep and work, check to Jinan large hospital under the accompanying of layman, checking and find patient's restriction of neck motion, the pain increased in layback, and cervical region tenderness is obvious, there is trapezoidal change in x-ray plain film vertebra joint, is diagnosed as: cervical spondylotic radiculopathy。The embodiment of the present invention 1 gained plaster is begun to use under the suggestion of doctor。
Using the embodiment of the present invention 1 gained plaster, once a day, patch wears 12 hours in cervical pain place every time, within 10 days, is a course for the treatment of。Using 10 days, pain is substantially alleviated, and numb limbs and tense tendons sense makes moderate progress。Using 20 days, pain disappears substantially, and feeling of numbness is substantially alleviated, and has strength on foot。Being continuing with 10 days, patient's self-induction is fully recovered。
Embodiment 2 one kinds treats the plaster of cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion and be prepared from (every part takes 10g): Radix Puerariae 14 parts, Herba Lycopodii 9 parts, Rhizoma Dioscoreae Nipponicae 15 parts, Rhizoma Et Radix Notopterygii 10 parts, Rhizoma Wenyujin Concisum 11 parts, Zaocys 13 parts, Herba Pyrolae 15 parts, Ramulus Uncariae Cum Uncis 9 parts, Sedum aizoon L. 5 parts, Squama Manis 9 parts。
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. being placed in non iron container by Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and stands 10 days, filters, obtains filtrate and filtering residue is standby；
2. step 1. middle gained filtering residue adds water, and the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 45 minutes, filters to get filtrate；
3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 12 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby；
4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 80 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 10g to spread upon in adhesive plaster or other substrate, make plaster。
Typical case two Cao XX, female, 52 years old, Weifang, Shandong personage。During last summer, accidentally drench with rain, conscious left side neck root after suffering from cold, shoulder and left upper arm pain, and extremity have slight feeling of numbness, originally do not take notice of, think and simply suffer from cold, but before 1 month, there is urgent micturition in patient, frequent micturition, the symptom of constipation, child sees that mother is uncomfortable and goes to hospital to check with regard to band mother, check and find patient's Wry Neck, cervical region is tilted to the right limited, when cervical region rotates to the left, the pain increased, cervical region all has obvious tenderness sense with doing scapula position, the X sheet display slight lateral bending of cervical flexure, it is diagnosed as: cervical spondylotic radiculopathy, owing to patient is not desired to the money that cost sons and daughters are too many, doctor is it have been suggested that use embodiment 2 gained plaster。
Using the embodiment of the present invention 2 gained plaster, once a day, patch is worn 12 hours every time, and cervical region and scapular region respectively paste one, within 10 days, are a course for the treatment of。Using 5 days, patch wears position the sensation of heating, feels well。Using 20 days, pain alleviates。Using 30 days, when noting posture and rest, substantially can avoid the generation of cervical pain symptom, omoplate place pain is wholly absent, and cervical region can comparatively swing normally, and defecation is normal, and have no side effect during use generation。
Embodiment 3 one kinds treats the plaster of cervical spondylotic radiculopathy, takes off the primary raw material stating weight proportion and is prepared from (every part takes 20g): Radix Puerariae 10 parts, Herba Lycopodii 7 parts, Rhizoma Dioscoreae Nipponicae 11 parts, Rhizoma Et Radix Notopterygii 6 parts, Rhizoma Wenyujin Concisum 6 parts, Zaocys 8 parts, Herba Pyrolae 10 parts, Ramulus Uncariae Cum Uncis 7 parts, Sedum aizoon L. 2 parts, Squama Manis 4 parts。
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. being placed in non iron container by Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and stands 3 days, filters, obtains filtrate and filtering residue is standby；
2. step 1. middle gained filtering residue adds water, and the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 35 minutes, filters to get filtrate；
3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 7 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby；
4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 65 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 3g to spread upon in adhesive plaster or other substrate, make plaster。
Three XX of typical case, man, 60 years old, people from Qingzhou, Weifang City, peasant。Cervical spondylotic radiculopathy history 1 year, cervicodynia is uncomfortable in chest, and with the symptom of blurred vision, nearest right arm sensation grips unable, and health has constrained sense, couches night and all feels uncomfortable, it is impossible to falls asleep and cause lethargy。Checking and find patient's instability of gait, hands grasping power is all not high, and right arm situation is even more serious, and compression of spinal cord is comparatively obvious, seeks medical advice everywhere, all to no effect, it is not intended on newspaper, see plaster of the present invention, have the attitude tried in arms and bought 2 courses for the treatment of。
Using the embodiment of the present invention 3 gained plaster, once a day, patch is worn 12 hours every time, and cervical region and right arm scapular region respectively paste one, within 10 days, are a course for the treatment of。Using 10 days, nighttime sleep has clear improvement, it is possible to sleeping。Using 20 days, both hands have obvious strength high, and mental attitude is taken on a new look to some extent, and pain symptom alleviates。Using 30 days, pain substantially alleviates, and mental restoration is good, and vision is also recovered to some extent。Using 50 days, other malaise symptoms disappear substantially, and patient's self-induction is fully recovered。
1, embodiment 4 one kinds treats the plaster of cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion and be prepared from (every part takes 25g): Radix Puerariae 12 parts, Herba Lycopodii 8 parts, Rhizoma Dioscoreae Nipponicae 13 parts, Rhizoma Et Radix Notopterygii 8 parts, Rhizoma Wenyujin Concisum 9 parts, Zaocys 10 parts, Herba Pyrolae 12 parts, Ramulus Uncariae Cum Uncis 8 parts, Sedum aizoon L. 4 parts, Squama Manis 6 parts。
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. being placed in non iron container by Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and stands 8 days, filters, obtains filtrate and filtering residue is standby；
2. step 1. middle gained filtering residue adds water, and the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 45 minutes, filters to get filtrate；
3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 10 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby；
4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 75 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 8g to spread upon in adhesive plaster or other substrate, make plaster。
Embodiment 5 one kinds treats the plaster of cervical spondylotic radiculopathy, take off the primary raw material stating weight proportion and be prepared from (every part takes 30g): Radix Puerariae 11 parts, Herba Lycopodii 7.5 parts, Rhizoma Dioscoreae Nipponicae 12 parts, Rhizoma Et Radix Notopterygii 7 parts, Rhizoma Wenyujin Concisum 8 parts, Zaocys 9 parts, Herba Pyrolae 11 parts, Ramulus Uncariae Cum Uncis 7.5 parts, Sedum aizoon L. 3 parts, Squama Manis 5 parts。
The preparation method of the plaster of above-mentioned treatment cervical spondylotic radiculopathy, step is:
1. being placed in non iron container by Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and stands 5 days, filters, obtains filtrate and filtering residue is standby；
2. step 1. middle gained filtering residue adds water, and the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 40 minutes, filters to get filtrate；
3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 9 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby；
4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 70 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 5g to spread upon in adhesive plaster or other substrate, make plaster。
Experimental example, in order to verify the present invention curative effect to cervical spondylotic radiculopathy, has chosen two or more person 200 people of cervical spondylotic radiculopathy symptom, and the mean age is 40 years old, it is divided into two groups according to the state of an illness, experimental group and matched group, often organize 100 people, basically identical to ensure two groups of situations。Experimental group uses embodiment 5 gained plaster, once a day, patch wears 12 hours every time, it within 10 days, it is a course for the treatment of, matched group uses the Chinese medicine of other oral medication cervical spondylotic radiculopathyes, observes 30 days time limits, and before experiment, first 1 day symptom to patient comprehensively checks, regularly check inquiry patient body situation and impression during experiment, and make a record。
1, the curative effect of two groups of medicines being recorded, result is table 1 below such as。(criterion, effectively: the malaise symptoms caused by cervical spondylotic radiculopathy has clear improvement；Invalid: the malaise symptoms caused by cervical spondylotic radiculopathy is unchanged。)
Table 1:
Analyze: as can be seen from Table 1, the effective percentage of cervical spondylotic radiculopathy is 99% by the present invention, exceeds matched group 19%, and effect is notable。
2, two groups of patient's applied mental changes being recorded, result is table 2 below such as。
Table 2:
Analyze: as can be seen from Table 2, medicament mode of the present invention is easier to be approved by patient, and major part represents per capita, Long-term taking medicine easily causes mental pressure, and appetite can be significantly affected, external used medicine is favored by more people on therapeutic modality, also more easily accepts and adheres to long-term treatment。Through to the analyses organizing experimental datas more it can be seen that plaster of the present invention is obvious for cervical spondylotic radiculopathy curative effect, total effective rate is up to 99%, and without any side effects, it is possible to reach the effect of pain-alleviating and network vessel-freeing comparatively rapidly。On therapeutic modality, the present invention is also easier to by patient's recognition and acceptance, it is possible to lay a good foundation for later treatment。The Chinese medicine composition of the present invention achieves significant effect, stable curative effect in treatment cervical spondylotic radiculopathy, has no side effect, is suitable for long-term taking。
Claims (2)
1. treat a plaster for cervical spondylotic radiculopathy, it is characterized in that, take off the primary raw material stating weight proportion and be prepared from: Radix Puerariae 8 parts, Herba Lycopodii 6 parts, Rhizoma Dioscoreae Nipponicae 9 parts, Rhizoma Et Radix Notopterygii 5 parts, Rhizoma Wenyujin Concisum 4 parts, Zaocys 7 parts, Herba Pyrolae 6 parts, Ramulus Uncariae Cum Uncis 6 parts, Sedum aizoon L. 1 part, Squama Manis 1 part。
2. the preparation method treating the plaster of cervical spondylotic radiculopathy, is characterized in that, step is:
1. being placed in non iron container by Radix Puerariae, Herba Lycopodii, Rhizoma Dioscoreae Nipponicae, Rhizoma Et Radix Notopterygii, Rhizoma Wenyujin Concisum, Zaocys, add ethanol, the consumption of ethanol is 2 times of crude drug gross weight, and sealing is placed in shady and cool ventilation place and stands 1 day, filters, obtains filtrate and filtering residue is standby；
2. step 1. middle gained filtering residue adds water, and the consumption of water is 4 times of filtering residue consumption, and adds Sedum aizoon L., Herba Pyrolae, Ramulus Uncariae Cum Uncis, Squama Manis, and intense fire is fried open, and fire of larding speech with literary allusions is slow to be decocted, and decocts to 30 minutes, filters to get filtrate；
3. step 1. middle gained filtrate being mixed with step 2. middle gained filtrate, stand 6 hours, filter, filtrate purifies again by the way of distillation, obtains distillate standby；
4. pot adds vegetable oil and rosin heating, do not stop stirring, to be mixed uniformly after add white vaseline and continue heated and stirred, excipient to be mixed old tender suitable time, close fire and be cooled to 60 DEG C, add step 3. middle gained distillate, after stirring, slow fire is endured slowly, is cooled to 65 DEG C after removing moisture, take 1g to spread upon in adhesive plaster or other substrate, make plaster。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201610095639.1A CN105688040A (en) | 2014-04-28 | 2014-04-28 | Plaster for treating cervical spondylotic radiculopathy |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201610095639.1A CN105688040A (en) | 2014-04-28 | 2014-04-28 | Plaster for treating cervical spondylotic radiculopathy |
| CN201410173689.8A CN103948863B (en) | 2014-04-28 | 2014-04-28 | A kind of plaster for the treatment of nerve root cervical vertebra sickness and preparation method thereof |
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| CN201410173689.8A Division CN103948863B (en) | 2014-04-28 | 2014-04-28 | A kind of plaster for the treatment of nerve root cervical vertebra sickness and preparation method thereof |
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| CN201610095639.1A Withdrawn CN105688040A (en) | 2014-04-28 | 2014-04-28 | Plaster for treating cervical spondylotic radiculopathy |
| CN201610095638.7A Withdrawn CN105597021A (en) | 2014-04-28 | 2014-04-28 | Plaster for treating nerve-root type cervical spondylopathy |
| CN201610095636.8A Withdrawn CN105561207A (en) | 2014-04-28 | 2014-04-28 | Medicine composition for treating nerve-root type cervical spondylosis |
| CN201410173689.8A Active CN103948863B (en) | 2014-04-28 | 2014-04-28 | A kind of plaster for the treatment of nerve root cervical vertebra sickness and preparation method thereof |
| CN201610095637.2A Withdrawn CN105561208A (en) | 2014-04-28 | 2014-04-28 | Traditional Chinese medicine unguent for treating cervical spondylotic radiculopathy |
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| CN201610095636.8A Withdrawn CN105561207A (en) | 2014-04-28 | 2014-04-28 | Medicine composition for treating nerve-root type cervical spondylosis |
| CN201410173689.8A Active CN103948863B (en) | 2014-04-28 | 2014-04-28 | A kind of plaster for the treatment of nerve root cervical vertebra sickness and preparation method thereof |
| CN201610095637.2A Withdrawn CN105561208A (en) | 2014-04-28 | 2014-04-28 | Traditional Chinese medicine unguent for treating cervical spondylotic radiculopathy |
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| CN104306536A (en) * | 2014-09-27 | 2015-01-28 | 王纬 | A plaster for treating nerve-root type cervical spondylosis and a preparing method thereof |
| CN104491072A (en) * | 2015-01-04 | 2015-04-08 | 霍山县中医院 | Traditional Chinese medicine for treating nerve-root type cervical spondylosis |
| CN104706793A (en) * | 2015-02-25 | 2015-06-17 | 黄桂荣 | Traditional Chinese medicine anaesthesia pain relieving tincture for treating nerve-root type cervical spondylosis |
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| CN101926969A (en) * | 2010-06-03 | 2010-12-29 | 陕西中医学院 | Traditional Chinese medicine composition for treatment of cervical spondylopathy and preparation method thereof |
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| CN1039674C (en) * | 1993-02-12 | 1998-09-09 | 武秋华 | Medicine "Yuntongling" for treating dizziness and headache |
| CN1188147C (en) * | 2001-11-08 | 2005-02-09 | 纪玉田 | Bone Bi-syndrome treating pill |
| CN100506274C (en) * | 2006-08-25 | 2009-07-01 | 范广友 | Traditional Chinese medicine for treating cervical vertebra disease |
| CN101721660A (en) * | 2008-10-22 | 2010-06-09 | 张彬 | Plaster for curing cervical spondylosis |
| CN103083609B (en) * | 2011-10-28 | 2014-12-31 | 刘亚芝 | Traditional Chinese medicine for treating cervical spondylosis, lumbar intervertebral disc herniation and ankylosing spondylitis |
| CN103070994B (en) * | 2013-02-17 | 2014-03-12 | 马云波 | Plaster for treating cervical and lumbar spondylosis |
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- 2014-04-28 CN CN201610095639.1A patent/CN105688040A/en not_active Withdrawn
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| CN103948863A (en) | 2014-07-30 |
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| CN105597021A (en) | 2016-05-25 |
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| CN105561207A (en) | 2016-05-11 |
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Address after: 712000 Qin Yang garden, No. 18 Century Avenue, Xianyang, Shaanxi, China 1-1-1001 Applicant after: Guo Ruying Address before: 250000 Ji'nan, Licheng District, Sun Village, white Valley heap No. two District No. 103 Applicant before: Guo Ruying |
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Application publication date: 20160622 |