CN102846915B - Yin-nourishing and kidney-tonifying pill for treating ankylosing spondylitis - Google Patents

Abstract

The invention discloses a yin-nourishing and kidney-tonifying pill for treating ankylosing spondylitis, which mainly consists of the following bulk pharmaceutical chemicals in parts by weight: Chinese angelica, prepared rehmannia root, vinegar tortoise shell, fruit of glossy privet, parasitic loranthus, rhizoma atractylodis macrocephalae, deer-horn glue, astragalus mongholicus, cortex lycii radicis, rhizoma anemarrhenae, salty golden cypress, vinegar turtle shell, Caulis Spatholobi, Chinese yam, sweet wormwood, large-leaved gentian, radix rehmanniae recen, polygala tenuifolia, white peony root and pawpaw. Firstly, all bulk pharmaceutical chemicals are smashed and evenly mixed, and then starch, refined honey and water are added and evenly mixed to obtain a pill. The yin-nourishing and kidney-tonifying pill for treating ankylosing spondylitis, which is disclosed by the invention, has the advantages of obvious curative effect, short course of treatment, low cost and no toxic or side effect. The yin-nourishing and kidney-tonifying pill for treating ankylosing spondylitis has an obvious curative effect on treating ankylosing spondylitis patients, and the effective ratio is above 90%.

Description

The Zinyin Bushen Pills for the treatment of ankylosing spondylitis

Technical field

The present invention relates to a kind of Chinese patent medicine and preparation method thereof, particularly relate to a kind of Zinyin Bushen Pills for the treatment of ankylosing spondylitis.

Background technology

Ankylosing spondylitis is a kind of agnogenic general, chronic, autoimmune disease.Pathological changes is mainly involved sacro-iliac joint, spinal column, is caused tetanic and fibrosis.At first the Most patients sacro-iliac joint gets involved, the later up cervical vertebra that is developed to, show as the lumbus sacrum pain of repeated relapsing, lumbar and back pain, have stiff sense, rise particularly evident morning, the waist limitation of activity, late period, the bow-backed deformity of spinal column, appearred in poker spine, some patients were can affect the periphery joint, affects hip joint and can cause femur head necrosis.Primary disease onset concealment, onset symptoms is changeable, lacks specificity, and very easily by mistaken diagnosis and delay treatment, severe one can cause human body deformity and disabled, has become the disease of serious harm human body health.

The Epidemiological study result shows, ankylosing spondylitis is apt to occur in person between twenty and fifty (10-40 year), and the onset peak age is 20-30 year.In China, the ankylosing spondylitis prevalence is 0.3%, and primary disease is multiple with the male, the domestic 10:1 that is reported as of men and women's ratio.

Along with ankylosing spondylitis the going deep into of factor research of curing the disease, although not clear at present to its mechanism of curing the disease, show may be relevant with heredity, environmental factors in research mostly.Although the clinical diagnosis and treatment aspect also has many puzzlements, aspect treatment, also obtained comparatively gratifying achievement.Medicine commonly used has the on-steroidal AID, chronic effect medicine, glucocorticoid, biological preparation and Chinese patent medicine etc. at present.Oral drugs are NSAID (non-steroidal anti-inflammatory drug), sulfasalazine, methotrexate, glucocorticoid and biological preparation etc.The on-steroidal AID, as traditional medicine, played positive role in treatment with in improving patients ' life quality, but the side effect of such medicine aspect gastrointestinal tract and nephrotoxicity thereof makes its clinical practice be subject to larger restriction.The chronic effect medicine has been brought into play certain effect slowing down or stop aspect the development of the state of an illness, but these side effects of pharmaceutical drugs are more, except digestive tract reaction, also have the untoward reaction such as nervous system, leukopenia, erythra, bone marrow depression, liver injury, pulmonary lesion.Although glucocorticoid has very strong antiinflammatory, analgesic activity, but due to its PD that can not well control ankylosing spondylitis, can not slow down the course of disease of ankylosing spondylitis, and more side effect is arranged, life-time service is more harm than good, generally as conventional, does not use.The state of an illness is alleviated and improved to the biological preparation that recent domestic has been developed new treatment ankylosing spondylitis, but, due to infusion reaction, Delayed onset allergy, infection chance and expensive etc., make clinical application be extremely restricted.Surgical intervention adopts artificial total hip arthroplasty, spinal vertebral osteotomy correct deformity.After operation, have a big risk, expensive, patient's misery, indolence, more very disable, and can form the fraud of curing the symptoms, not the disease.

In recent decades, differentiation of tcm treatment ankylosing spondylitis has been obtained larger progress, with Chinese medical theory, the various clinical manifestations of ankylosing spondylitis are carried out to dialectical analysis, warming YANG to expel cold has been proposed, replenishing kidney, strengthening waist, clearing away heat-damp and promoting diuresis, the Therapeutic Method such as blood circulation promoting and blood stasis dispelling, and obtained good curative effect.Because Chinese medicine has no side effect mostly, untoward reaction is few, especially reproductive system is had no adverse effects simultaneously.Therefore the development for the Chinese patent medicine of mandatory spinal column more and more receives publicity in recent years.

Summary of the invention

The technical problem to be solved in the present invention is: according to the current condition of current treatment ankylosing spondylitis, the invention provides that a kind of evident in efficacy, short treating period, expense are low, the Zinyin Bushen Pills of the treatment ankylosing spondylitis that has no side effect.

In order to address the above problem, the technical solution used in the present invention is:

The invention provides a kind of Zinyin Bushen Pills for the treatment of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills is by 15～25 parts of crude drug Radix Angelicae Sinensis, 40～55 parts of Radix Rehmanniae Preparata, 40～60 parts of vinegar Carapax Et Plastrum Testudiniss, 20～30 parts of Fructus Ligustri Lucidi, 18～28 parts of Herba Taxillis, 40～55 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 24～40 parts of Colla cornus cervis, 45～55 parts of the Radixs Astragali, 26～42 parts of Cortex Lycii, 24～36 parts of the Rhizoma Anemarrhenaes, 15～25 parts of stir-baked CORTEX PHELLODENDRI with salt solution, 40～60 parts of Carapax Trionycis (processed with vinegar), 40～55 parts of Caulis Spatholobis, 20～30 parts of Rhizoma Dioscoreaes, 35～50 parts of Herba Artemisiae Annuaes, 16～28 parts of Radix Gentianae Macrophyllae, 20～28 parts of Radix Rehmanniae, 20～26 parts of Radix Polygalaes, 16～25 parts of 18～25 parts of the Radix Paeoniae Albas and Fructus Chaenomeliss are prepared from.

Zinyin Bushen Pills according to above-mentioned treatment ankylosing spondylitis, described Zinyin Bushen Pills is by 18～22 parts of crude drug Radix Angelicae Sinensis, 45～50 parts of Radix Rehmanniae Preparata, 45～55 parts of vinegar Carapax Et Plastrum Testudiniss, 23～28 parts of Fructus Ligustri Lucidi, 22～26 parts of Herba Taxillis, 45～50 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 26～32 parts of Colla cornus cervis, 48～52 parts of the Radixs Astragali, 30～38 parts of Cortex Lycii, 26～32 parts of the Rhizoma Anemarrhenaes, 18～22 parts of stir-baked CORTEX PHELLODENDRI with salt solution, 45～55 parts of Carapax Trionycis (processed with vinegar), 45～50 parts of Caulis Spatholobis, 23～28 parts of Rhizoma Dioscoreaes, 40～45 parts of Herba Artemisiae Annuaes, 20～26 parts of Radix Gentianae Macrophyllae, 24～27 parts of Radix Rehmanniae, 22～25 parts of Radix Polygalaes, 18～22 parts of 20～24 parts of the Radix Paeoniae Albas and Fructus Chaenomeliss are prepared from.

A kind of Zinyin Bushen Pills for the treatment of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills is by 15～25 parts of crude drug Radix Angelicae Sinensis, 40～55 parts of Radix Rehmanniae Preparata, 40～60 parts of vinegar Carapax Et Plastrum Testudiniss, 20～30 parts of Fructus Ligustri Lucidi, 18～28 parts of Herba Taxillis, 40～55 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 24～40 parts of Colla cornus cervis, 45～55 parts of the Radixs Astragali, 26～42 parts of Cortex Lycii, 24～36 parts of the Rhizoma Anemarrhenaes, 15～25 parts of stir-baked CORTEX PHELLODENDRI with salt solution, 40～60 parts of Carapax Trionycis (processed with vinegar), 40～55 parts of Caulis Spatholobis, 20～30 parts of Rhizoma Dioscoreaes, 35～50 parts of Herba Artemisiae Annuaes, 16～28 parts of Radix Gentianae Macrophyllae, 20～28 parts of Radix Rehmanniae, 20～26 parts of Radix Polygalaes, 18～25 parts of the Radix Paeoniae Albas, 16～25 parts of Fructus Chaenomeliss, 45～60 parts of Fructus Lycii, 20～30 parts of Radix Polygoni Multiflori Preparatas, 18～26 parts, Fructus Mori, 20～28 parts of Rhizoma Polygonati Odorati, 20～26 parts of Herba Dendrobiis, 35～55 parts of Rhizoma Cibotii, 35～50 parts of 18～26 parts of Rhizoma Picrorhizae and Radix Stellariaes are prepared from.

Zinyin Bushen Pills according to above-mentioned treatment ankylosing spondylitis, described Zinyin Bushen Pills is by 18～22 parts of crude drug Radix Angelicae Sinensis, 45～50 parts of Radix Rehmanniae Preparata, 45～55 parts of vinegar Carapax Et Plastrum Testudiniss, 23～28 parts of Fructus Ligustri Lucidi, 22～26 parts of Herba Taxillis, 45～50 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 26～32 parts of Colla cornus cervis, 48～52 parts of the Radixs Astragali, 30～38 parts of Cortex Lycii, 26～32 parts of the Rhizoma Anemarrhenaes, 18～22 parts of stir-baked CORTEX PHELLODENDRI with salt solution, 45～55 parts of Carapax Trionycis (processed with vinegar), 45～50 parts of Caulis Spatholobis, 23～28 parts of Rhizoma Dioscoreaes, 40～45 parts of Herba Artemisiae Annuaes, 20～26 parts of Radix Gentianae Macrophyllae, 24～27 parts of Radix Rehmanniae, 22～25 parts of Radix Polygalaes, 20～24 parts of the Radix Paeoniae Albas, 18～22 parts of Fructus Chaenomeliss, 48～55 parts of Fructus Lycii, 23～27 parts of Radix Polygoni Multiflori Preparatas, 20～25 parts, Fructus Mori, 23～27 parts of Rhizoma Polygonati Odorati, 22～25 parts of Herba Dendrobiis, 36～45 parts of Rhizoma Cibotii, 40～45 parts of 20～24 parts of Rhizoma Picrorhizae and Radix Stellariaes are prepared from.

According to the Zinyin Bushen Pills of above-mentioned treatment ankylosing spondylitis, the preparation method of described Zinyin Bushen Pills is:

At first the proportioning ratio according to the Zinyin Bushen Pills of above-mentioned treatment ankylosing spondylitis takes various crude drug, the various crude drug that take are pulverized respectively, cross 100 mesh sieves, by the various crude drug medicated powder mix homogeneously after pulverizing, obtain mixing fine powders, then according to every 100g mixing fine powders, add the ratio of starch 2g to add the starch mix homogeneously, after mixing, according to every 100g mixing fine powders, add the ratio of refined honey 10～20g to add refined honey, and add the ratio of water 40g to add required water according to every 100g mixing fine powders, then make pill according to conventional method, finally carry out successively drying, bag charcoal clothing, the Pulvis Talci polishing, obtain the Zinyin Bushen Pills of product treatment ankylosing spondylitis.

The pharmacological action of the various crude drug of the present invention:

Radix Angelicae Sinensis: warm in nature, acrid in the mouth, sweet; Enter the heart, liver, spleen, lung four warps.Effect: 1, nourshing blood and promoting blood circulation: this product sweet in the mouth and weighing, therefore specially can enrich blood, its gas is light and hot, again can promoting the circulation of blood, invigorating middle warmer has, in row, benefit is arranged, the sincere gas medicine in blood, also the panacea in blood is also.This product is good hematonic, therefore be applicable to the various syndromes that blood deficiency causes.2, promoting blood circulation and stopping pain: Radix Angelicae Sinensis can pursue congestion, and tissue regeneration promoting blood makes unobstructed vessel and gas parallel, flows round without stopping.Be usually used in traumatic injury stasis of blood pain, carbuncle stasis pain, the stagnant stomachache of the stasis of blood in puerperal, the card such as rheumatic arthralgia and meridians are unfavorable, this product has good promoting blood circulation and stopping pain effect.3, nourishing blood for regulating menstruation.4, loosening bowel to relieve constipation: few for blood deficiency Tianjin, the dryness of the intestine constipation.Disease is seen: constipation, and lusterless complexion, severe palpitation, have a dizzy spell.5, sending down the abnormal ascending QI cough-relieving: the hot temperature of Radix Angelicae Sinensis, enter lung meridian, depressed lung-energy dispersing is arranged, the merit of sending down the abnormal ascending QI cough-relieving.6, Radix Angelicae Sinensis should be for headache due to deficiency of blood and headache due to blood stasis person.

Radix Rehmanniae Preparata: have another name called Radix Rehmanniae Preparata, slightly warm in nature, sweet in the mouth; Enter the heart, liver, stomach three warps.Effect: 1, nourishing the kidney and liver: the Radix Rehmanniae Preparata darkish complexion, blackly can enter kidney, spermatogenesis is mended marrow, be again the key medicine of enriching blood, blood stored in the liver, enriching blood is the body of the liver benefiting, and The liver and the kidney have a common source, and essence and blood is changed mutually, and seminal emission, hectic fever, the empty diseases of essence and blood two, therefore Radix Rehmanniae Preparata has the effect of nourishing the kidney and liver.Asthenia interior-heat, lumbago due to renal deficiency, the deficiency of liver-blood hypochondriac pain controlled commonly used.2, deficiency of YIN cough with asthma: this product darkish complexion, enter kidney channel, for the key medicine of nourishing kidney yin, because of kidney governing inspiration, if the kidney loss, gas loses to take the photograph and receives and superinverse, and causes cough and asthma.Available Radix Rehmanniae Preparata improving inspiration by invigorating the kidney.3, quench one's thirst: the plain body deficiency of YIN, multiple excessive because of the labor wish, more consume cloudy Tianjin, damage of kidney-YIN, hyperactivity of fire caused by deficiency of YIN, upper bright lung gold, then cause and suffer from a deficiency of the kidney and the dryness of the lung, sends out as quenching one's thirst.Insufficiency of kidney-YANG, urinary micturition, muddy as fat, or urinate sweet, dry mouth and tougue, red tongue, deep pulse is counted accurately, first-selected Radix Rehmanniae Preparata, enriching yin and nourishing kidney, quench one's thirst from stopping.4, tonifying blood and regulating menstruation: the Radix Rehmanniae Preparata sweet in the mouth, warm in naturely enter the Liver and kidney warp, sweet can the benefit, Wen Nengtong, menstruation comes from the sea of blood, and normally whether regularly catharsis, relevant with Liver and kidney, so the Radix Rehmanniae Preparata nourishing blood for regulating menstruation is considered as to panacea, amenorrhea, metrorrhagia, the puerperal abdonimal pain controlled commonly used.

Radix Rehmanniae: this product sweet-bitter flavor, cold in nature; Enter the heart, liver, kidney channel.Effect: this product has heat clearing away, the YIN nourishing of promoting the production of body fluid, and the effect such as nourish blood; Commonly use and control fever due to yin deficiency, quench one's thirst, spit blood, epistaxis, metrorrhagia, menoxenia, frequent fetal movement, the moon is hindered the cards such as constipation.

Carapax Et Plastrum Testudinis: this product salty in the mouth, sweet, cold nature; Return liver, kidney, heart channel.Effect: this product has nourishing YIN for suppressing the hyperactive YANG, the kidney tonifying bone strengthening, and the effects such as reinforcing the heart nourish blood.Commonly use and control deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, have a dizzy spell, stirring-up of pathogenic wind in the interior resulting from deficiency, and the muscles and bones flaccidity is soft, the forgetful card that waits of having a guilty conscience.

The vinegar Carapax Et Plastrum Testudinis: its preparation method is: get clean Carapax Et Plastrum Testudinis, fry to surperficial faint yellow with sand according to scalding method (appendix II D), take out quench in vinegar, drying; Used time smashs to pieces; Every 100kg Carapax Et Plastrum Testudinis vinegar 20kg.

Fructus Ligustri Lucidi: this product sweet in the mouth, hardship, cool in nature; Enter liver, kidney channel.Effect: this product has liver and kidney tonifying, clearind deficient heat, the effects such as improving eyesight.Commonly use and control dizzy margins of eyelids, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, the diseases such as poor vision.

Herba Taxilli: this product bitter in the mouth, sweet, property is flat; Enter liver, kidney channel.Effect: this product has invigorating the liver and kidney, bone and muscle strengthening, wind-damp dispelling, the effect such as antiabortive; Cure mainly soreness of waist and knee joint, a little less than the muscles and bones flaccidity, limbs are hemiplegia, rheumatic arthralgia, and head is wrong dizzy, frequent fetal movement, the cards such as metrostaxis; Commonly use in addition the dispelling the wind and dampness pathogens arthralgia pain, soreness of the waist and knees, muscles and bones is unable, and the metrorrhagia warp is many, blood leaking in gestation, frequent fetal movement, the cards such as hypertension.

The Rhizoma Atractylodis Macrocephalae: this product bitter in the mouth, sweet, warm in nature; Return spleen, stomach warp.Effect: this product has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, the effect such as antiabortive.Commonly use and control insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, the cards such as frequent fetal movement.

Rhizoma Atractylodis Macrocephalae (parched): be that the micro-stir-fry of Rhizoma Atractylodis Macrocephalae sheet is extremely light yellow, taking-up is dried in the air cool.

Colla cornus cervi: this product sweet in the mouth, salty, warm in nature; Return liver, kidney channel.Effect: this product has nourishing the liver and kidney, adds the effects such as essence hemostasis; Be usually used in treating asthenia thin and weak, soreness of waist and knee joint, night nocturnal emission, the diseases such as bleeding not during menses.

The Radix Astragali: sweet in the mouth, slightly warm in nature; Enter lung, spleen, liver, kidney channel.Effect: the Radix Astragali has the effect that benefiting QI for strengthening the superficies, arresting sweating are admittedly de-, hold in the palm skin ulcer granulation promoting, inducing diuresis to remove edema.Be used for the treatment of the deficiency of vital energy weak, sinking of QI of middle-JIAO, the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst and do not hold back for a long time, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.

Cortex Lycii: this product sweet in the mouth, light, bitter, cold in nature enters liver, lung, kidney, three warmers four warps; This product has analgesic, blood sugar lowering is arranged, blood pressure lowering, calmness, the pharmacological action such as antibacterial; Effect has the effects such as cooling blood for hemostasis, clearing deficient heat, eliminating heat from the lung, heat clearing away YIN nourishing, heat-clearing and toxic substances removing; There is the removing toxic substances of significantly bringing down a fever, except the function of disliking meat.

The Rhizoma Anemarrhenae: this product bitter in the mouth, sweet, cold in nature; Return lung, stomach, kidney channel.Effect: this product has clearing away heat-fire, promotes the production of body fluid and the effect such as moisturizes; The cards such as epidemic febrile disease, high hot excessive thirst, cough and asthma, cough caused by dryness, constipation, osteopyrexia and fever, restlessness of asrhenia type and insomnia, the stranguria with turbid discharge of quenching one's thirst of controlling commonly used.

Cortex Phellodendri: this product bitter in the mouth, cold in nature; Enter kidney, bladder, large intestine channel.Effect: this product has heat clearing and damp drying, and pathogenic fire purging is except steaming, the effects such as detoxification sore treatment.Commonly use and control damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity is warded off, hectic fever due to YIN-deficiency consumptive disease heat, night sweat, seminal emission, sore swollen toxin, the diseases such as eczema pruritus.

Stir-baked CORTEX PHELLODENDRI with salt solution: its preparation method is: gets Cortex Phellodendri silk or piece, mixes thoroughly with saline, and slightly vexed, after the salt water tumbler exhausts, put in the parch container, by slow fire heating, fried dry, taking-up is dried in the air cool, and sieve goes chip to get final product (the every 100kg of Cortex Phellodendri silk or piece, use Sal 2kg).Stir-baked CORTEX PHELLODENDRI with salt solution has the nourishing YIN to lower pathogenic fire effect.Be usually used in hyperactivity of fire caused by deficiency of YIN, the cards such as night sweat hectic fever due to YIN-deficiency.

Carapax Trionycis (processed with vinegar): this product salty in the mouth, cold in nature; Enter liver, kidney channel.Effect: this product has nourishing YIN for suppressing the hyperactive YANG, the effects such as hard masses softening and resolving; Cure mainly fever due to yin deficiency, consumptive fever hectic fever due to YIN-deficiency, stirring of wind due to deficiency of YIN, amenorrhea lump in the abdomen, the cards such as chronic malaria malaria with splenomegaly.Carapax Trionycis (processed with vinegar) has the effect of convergence, removing toxic substances, eliminating stasis to stop pain; Vinegar system can also strengthen medicine and enter the liver removing food stagnancy, the effect of hard masses softening and resolving.

Caulis Spatholobi: this product bitter in the mouth, sweet, warm in nature, return liver, kidney two warps.Effect: energy promoting blood flow to regulate menstruation, Kuai, a state in the Zhou Dynasty muscle dredging collateral, blood circulation promoting and enriching.This product is sweet, warm in nature, is apt to, into the Liver Channel blood system, can invigorate blood circulation, and the promoting the circulation of blood of can enriching blood again, again can relaxing muscles and tendons and activating QI and blood in the collateral.This product energy nourishing blood and promoting blood circulation, dredge the meridian passage.For oldaged physically weak, blood failing to nourish tendons, limbs are weak, paralysis and numbness.

Rhizoma Dioscoreae: this product sweet in the mouth, property are put down, and enter lung, spleen, kidney channel.Effect: this product has strengthening the spleen and tonifying the lung, stomach reinforcing the kidney invigorating, the benefit of reinforcing the kidney essence, hearing-improing and eyesight improving, help the five internal organs, bone and muscle strengthening, grow the effects such as will is calmed the nerves, life lengthening.Commonly used control that weakness of the spleen and stomach, lassitude, inappetence, chronic diarrhea and dysentery, insufficiency of lung-QI are dry, phlegm dyspnea cough, kidney qi loss, soreness of the waist and knees, lower limb flaccidity are weak, the red disease such as swollen, fat of the frequent micturition of quenching one's thirst, seminal emission premature ejaculation, leukorrhagia nebulousurine, skin.

Herba Artemisiae Annuae: this product bitter in the mouth, suffering, cold in nature; Enter liver, gallbladder, three warmers, kidney channel.Effect: this product has deficiency-heat clearly thoroughly, and removing heat from blood is except steaming, except steaming, the effects such as preventing the attack (or recurrence) of malaria.Be usually used in the pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, the cards such as jaundice due to damp-heat.This product clearing up internal heat by using drugs of bitter in taste and cold in nature, hot fragrant thoroughly loose, be apt to make a cloudy minute latent heat thoroughly to reach outer loose, be the fever due to yin deficiency key medicine, have in addition expelling summer-heat concurrently, cut cruel merit.

Radix Gentianae Macrophyllae: this product acrid in the mouth, hardship, cold nature; Enter stomach, liver, gallbladder meridian.Effect: this product has wind-damp dispelling, relaxing muscles and tendons network, the effects such as clearind deficient heat; Be usually used in rheumatic arthralgia, the contracture of muscle arteries and veins, joint is ached, afternoon fever, the cards such as infantile malnutrition heating.

Radix Polygalae: this product bitter in the mouth, suffering, slightly warm in nature; Enter the heart, kidney, lung meridian.Effect: this product has the Fructus Alpiniae Oxyphyllae of calming the nerves, eliminates the phlegm, and the effects such as detumescence.Be usually used in the insomnia and dreamful sleep that disarmony between the heart and kidney causes, forgetful palpitation with fear, staring spells, expectoration is not well, sore swollen toxin, the cards such as breast swell and pain.

The Radix Paeoniae Alba: claim again Radix Paeoniae Alba, cold nature, bitter in the mouth, acid, enter liver, spleen two warps.Effect: 1, nourishing blood to suppress the hyperactive liver: this product bitter in the mouth, acid, enter Liver Channel, can tonifying liver blood and easing the affected liver.Be usually used in the cards such as menoxenia, dysmenorrhea.2, astringing YIN to stop sweating: this product picric acid, can nourish blood and seek, thus the energy astringing YIN to stop sweating, the cards such as spontaneous perspiration commonly used, night sweat, yellowish perspiration.3, pain relieving in slow: this product picric acid, be slightly cold, enter liver spleen two warps, can nourishing blood to suppress the hyperactive liver and relieving spasm to stop pain.Be usually used in stomachache, hypochondriac pain, have a stomachache, have loose bowels, the card such as dysentery.4, suppressing liver-YANG: this product is bitter can nourishing YIN, and acid can restrain, enters again Liver Channel, and the loose evil of liver libido is held back, therefore the energy suppressing liver-YANG is usually used in the card of excessive rising of liver-YANG.

Fructus Chaenomelis: this product sweet in the mouth, property is put down, is slightly cold; Enter liver, spleen channel.Effect: this product have after aid digestion can also relieve summer heat quench one's thirst, nourishing the lung to arrest cough.Its distinctive Fructus Chaenomelis ferment energy clearing away heart-fire and moistening the lung, can also help digest, control gastropathy, and its exclusive Fructus Chaenomelis alkali has antitumor efficacy, and the lymphoid leukemia cell is had to strong active anticancer.

Fructus Lycii: sweet in the mouth, property are put down, and enter liver, kidney, lung meridian.Effect: nourishing the liver and kidney, lung moistening, replenishing vital essence to improve eyesight; For asthenia damage of essence, caused by liver and kidney deficiency, soreness of waist and knee joint, vertigo and tinnitus, interior-heat is quenched one's thirst, blood deficiency and yellow complexion, blurred vision is not clear, impotence and seminal emission, cough due to consumptive disease, the cards such as taking fluids profusely of quenching one's thirst.

Radix Polygoni Multiflori Preparata: be the Preparation process product of Radix Polygoni Multiflori, the piece sheet that manufactured goods are irregular shrunk, thick about 1cm, surperficial pitchy or sepia, uneven, matter is hard, section cutin sample, sepia or black.This taste is micro-sweet and pained, warm in nature; Enter liver, the heart, kidney channel.Effect: this product has invigorating the liver and kidney, benefiting essence-blood, black beard and hair, the effects such as bone and muscle strengthening; Be usually used in blood deficiency and yellow complexion, vertigo and tinnitus, early whitening of beard and hair, soreness of the waist and knees, numb limbs and tense tendons, bleeding not during menses, chronic malaria body void; The cards such as hyperlipidemia.Main suitable crowd is fatty liver, three-hypers, obesity, insomnia, alopecia, teen-ager leukotrichia and sub-health population.

Fructus Mori: this product sweet in the mouth, acid, cold in nature; Enter the heart, liver, kidney channel.Effect: this product has the YIN nourishing of enriching blood, and promotes the production of body fluid and the effect such as moisturizes; Be usually used in vertigo and tinnitus, palpitation and insomnia, early whitening of beard and hair, Tianjin wound is thirsty, and interior-heat is quenched one's thirst, the cards such as blood deficiency and constipation.This product tonifying liver, kidney tonifying, relieve dizziness, high fever, infantile convulsions, epilepsy, etc., and grows liquid; Control hepatic and renal YIN deficiency, quench one's thirst, constipation, order is dark, tinnitus, scrofula, articular instability.

Rhizoma Polygonati Odorati: this product sweet in the mouth, property is flat; Enter lung, stomach warp.Effect: this product has nourishing YIN and moistening the lung, the effects such as nourishing the stomach to promote the production of body fluid.Commonly use and control cough caused by dryness, chronic cough, the dry throat and mouth of the cloudy liquid consumption of calentura wound, interior-heat is quenched one's thirst, and deficiency of YIN diseases caused by exogenous pathogenic factor are dizzy dizzy, the cards such as muscle arteries and veins spasm and pain.

Herba Dendrobii: have another name called Herba Dendrobii, this product has reinforcing stomach reg fluid, the effects such as nourishing YIN and clearing away heat.There is health invigorating, strengthen the spleen and stomach, the hepatoprotective function of gallbladder promoting, clearind deficient heat, suppress tumor, nourishes the effects such as skin.

Rhizoma Cibotii: this product bitter in the mouth, liver, warm in nature; Return liver, kidney channel.Effect: this product has wind-damp dispelling, invigorating the liver and kidney, the effects such as strong waist knee joint; Dispelling the wind and dampness pathogens arthralgia pain commonly used, soreness of the waist and knees, weakness of the lower extremities, frequent micturition, the enuresis, the cards such as leukorrhagia.The external application incised wound.

Rhizoma Picrorhizae: this product enters liver, stomach, large intestine channel.Effect: this product has reducing the asthenic fever, and the effects such as infantile malnutrition with fever, heat clearing and damp drying, eliminating fire and detoxication disappear; Cure mainly deficiency of YIN hectic fever due to YIN-deficiency, hectic fever night sweat, children's's infantile malnutrition, damp-heat dysentery, jaundice, spit blood, knob blood, conjunctival congestion and swelling pain, carbuncle skin infection, the cards such as hemorrhoid toxic swelling.

Radix Stellariae: this product sweet in the mouth, cold nature; Return liver, stomach warp.Effect: this product has clearing away heat and cooling blood, reducing the asthenic fever, the clear effect such as xeothermic; The cards such as asthenia hectic fever due to YIN-deficiency, deficiency of YIN chronic malaria, the lean hot weakness and emaciation of children's of controlling commonly used.

The compatibility mechanism of medicament composing prescription of the present invention: the liver-kidney yin deficiency arthralgia pain, due to the QI and blood deficiency of the liver and kindey, causes muscles and bones mistake to be supported, the damp and hot exopathogen that waits of wind and cold is availed oneself of the opportunity to get in, and causes obstruction of meridians and collaterals, " stagnation of QI and blood may bring about pain ", the muscles and bones joint loses supports, " Rong Ze pain ", the Radix Rehmanniae Preparata YIN nourishing of enriching blood, beneficial essence is filled out marrow, soreness of the waist and knees for the Liver and kidney blood and essence asthenia, vertigo and tinnitus, the hectic fever hectic fever due to YIN-deficiency of insufficiency of kidney-YANG, night sweat is the YIN nourishing principal agent." Margarita illiteracy ": " the main gas of enriching blood, kidney nourishing water, beneficial kidney-Yang ".The Fructus Lycii invigorating the liver and kidney, improving eyesight, for deficiency of the liver and kindey, soreness of waist seminal emission, and have a dizzy spell etc.Collective Notes to the Canon of Materia medica: " nourishing the essence and strengthening QI, prosperous and powerful vagina ", the Carapax Et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, replenishing kidney and strengthening bone, the moon that can nourishing the liver and kidney and move back interior-heat, submersiblely again fall liver-yang and cease endogenous wind, and three medicines share, and are monarch drug altogether; Herba Taxilli wind-damp dispelling, liver and kidney tonifying, bone and muscle strengthening, can wind-damp dispelling, the liver and kidney tonifying that can nourish blood again, and bone and muscle strengthening, can control deficiency of nutrient QI and blood, the rheumatic arthralgia of deficiency of the liver and kindey, soreness of the waist and knees, the unable card that waits of muscles and bones." Japan hanako materia medica ": " helping muscles and bones, beneficial blood vessels ".Colla cornus cervi temperature compensation Liver and kidney, Radix Stellariae, for fever due to yin deficiency, night sweat, osteopyrexia and fever." book on Chinese herbal medicine justice ": " and not bitter the letting out of bringing down a fever managed the moon and not ascension, Gu the good medicine of deficiency-heat ".The Carapax Trionycis nourishing YIN for suppressing the hyperactive YANG is the key medicine of controlling fever due to yin deficiency, and the Herba Artemisiae Annuae clearind deficient heat is except hectic fever due to YIN-deficiency." book on Chinese herbal medicine is newly organized ": " moving back summer-heat "." medical center is wanted ": " damp and hot in purifying the blood, the card that the subcutaneous ulcer of harnessing the Yellow River and stagnated fire are not easypro ".The Caulis Spatholobi circulation of qi promoting is enriched blood, relaxing muscles and tendons and activating QI and blood in the collateral, treatment rheumatic arthralgia, arthralgia, numb limbs and tense tendons.Supplementary Amplifications of the Compendium of Materia Medica: " its rattan is invigorated blood circulation most, and abdomen waist knee joint is wind-phlegm ".The above-mentioned several medicines of liana rubber " strengthening bone and muscle, the clothes of muscles and bones, and wine ... " share, and play altogether the effect of enriching yin and nourishing kidney, are ministerial drug, Radix Astragali tonifying Qi and lifting yang, and benefit is defended consolidating superficial resistance, Cortex Lycii, removing heat from blood moves back steaming, the lung heat clearing pathogenic fire reducing." book on Chinese herbal medicine is newly organized ": " moving back summer-heat ", Rhizoma Atractylodis Macrocephalae air making-up and spleen enlivening, dampness diuretic, the Rhizoma Anemarrhenae is nourshing Yin and drynsessmoistening prescription, the effect of promoting the production of body fluid to quench thirst." medication on the analogy of natural things ": " rush down without radical cure kidney fire, treat the hectic fever due to YIN-deficiency that Tianjin is arranged, stop the heat of asthenia, the moon that excessiveization is molten." the Radix Gentianae Macrophyllae wind-damp dispelling, stopping numbness pain, reducing the asthenic fever, clearing away damp-heat.The Fructus Ligustri Lucidi invigorating the liver and kidney, essentials of Matea Medica: " liver and kidney tonifying, settling five organs, strong waist knee joint, improve visual and auditory acuity, black beard and hair, mend wind void, except all kinds of diseases and ailments." Chinese angelica blood supplementing, invigorate blood circulation, pain relieving, the Radix Polygoni Multiflori invigorating the liver and kidney, be adjuvant drug altogether; The Rhizoma Dioscoreae supplementing QI and nourishing YIN, spleen reinforcing lung kidney, Cortex Phellodendri heat clearing away, dampness, bring down a fever except steaming, for making medicine.Total side entirely that sees, with enriching yin and nourishing kidney, logical to adjust governor vessel be main, focuses on waist sacrum, the neck corrected due to the hepatic and renal YIN deficiency, carries on the back into hip, the mark of knee joint soreness, stiff, joint deformity, separately with invigorate the spleen and warm the kidney, adjust the liver the kidney invigorating, channels sootheing and network vessel quickening to be to consolidate, reinforcement and elimination in combination, pathogenesis hits, side's medicine forms rationally, and patient feels without discomfort at period in a medicine, favourable clothes for patients use.

Positive beneficial effect of the present invention:

1, social benefit: the Zinyin Bushen Pills that the present invention treats ankylosing spondylitis plays determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs in clinical, by the cause of disease, dissolves, and applies to clinical, after generally taking medicine 10 days, patients clinical sx↓, pain relief, effectively shorten patient's treatment time, alleviated patient's misery; On the effect of liver,spleen,kidney deficiency of YIN numbness disease, obtained further improving simultaneously, perfect therapeutic scheme and the summary of hepatic and renal YIN deficiency numbness, also effectively fill up the prescription blank in treatment Liver and kidney arthromyodynia, for social group's arthromyodynia patient has solved misery, certain social influence and public praise publicity have been produced.

2, economic benefit: the Zinyin Bushen Pills (soup) that the present invention treats ankylosing spondylitis moves to and has effectively solved clinically most of arthromyodynia caused because of deficiency of spleen-YANG and kidneyYANG, one side's one disease, press because of prescribe medicine, curative effect is outstanding, economical cheap, patient easily accepts, and has also given prominence to the traditional Chinese medical herbal treatment arthromyodynia simultaneously.In the development of Chinese medicine osteopathia, not only develop, also produced certain economic benefit.

3, potential benefit: arthromyodynia is also many clinical middle yang deficiency of spleen and stomache patient, general sickness rate is more than 65%, clinical summary by nearly ten years, the deficiency of spleen-YANG and kidneyYANG patient is ascendant trend gradually, the research foundation is provided in clinical research to us, if the hepatic and renal YIN deficiency of the present invention arthromyodynia side medicine Zinyin Bushen Pills (soup) can be promoted in clinical practice, will bring glad tidings to numerous patients, also to hospital, bring good economic benefit and social benefit.

4, utilize Drug therapy patients with ankylosing spondylitis of the present invention, its therapeutic effect is remarkable, and effective percentage reaches more than 90%.

Utilize the clinical practice data of Drug therapy patients with ankylosing spondylitis of the present invention:

Choose patients with ankylosing spondylitis 500 examples in year February in May, 2006 to 2012, male patient's 320 examples wherein, female patient's 180 examples; Minimum 25 years old of age, maximum 72 years old, average 46 years old; 500 routine patient's middle-young patients have 312 examples, and middle aged patient has 116 examples, and the gerontal patient has 72 examples; The shortest person of the course of disease more than 20 day, the elder of the course of disease reaches more than 20 year.Above patient all meets " traditional Chinese medical science disease Standardization of diagnosis and curative effect " of State Administration of Traditional Chinese Medicine's issue in 1994.

The diagnostic criteria of ankylosing spondylitis: (1) low back pain continues at least 3 months, after the pain activity, can alleviate, and after rest, does not alleviate.(2) lumbar vertebra is at the limitation of activity of anteroposterior position and lateroflexion direction.(3) normal person of more same age of thorax mobility, sex reduces.Possess one-sided III～IV level or bilateral II～III level iconography sacrum ilium and close scorchingly, add in 3 of clinical criteria at least 1.Waist sacrum, back pain, the spinal column limitation of activity, morning deadlock, ache in part, walk unfavorable, the extremity flaccidity is soft unable, dizzy, tinnitus, thirsty and dry pharynx, vexed insomnia.Wasting and atrophy of muscle, night sweat, feverish sensation in the palms and soles.Red tongue, tongue is few or strip off, deep-thready pulse or count accurately.

Therapeutic Method: it is Zinyin Bushen Pills that patients with ankylosing spondylitis is taken the enriching yin and nourishing kidney Chinese patent medicine pill that the present invention treats ankylosing spondylitis, the Zinyin Bushen Pills Chinese patent medicine pill that Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Fructus Lycii, vinegar Carapax Et Plastrum Testudinis, Fructus Ligustri Lucidi, Herba Taxilli, Rhizoma Cibotii, Rhizoma Atractylodis Macrocephalae (parched), Colla cornus cervi, Radix Stellariae, the Radix Astragali, Cortex Lycii, the Rhizoma Anemarrhenae, stir-baked CORTEX PHELLODENDRI with salt solution, Radix Polygoni Multiflori Preparata, Carapax Trionycis (processed with vinegar), Caulis Spatholobi, Rhizoma Dioscoreae, Herba Artemisiae Annuae, Radix Gentianae Macrophyllae, Radix Rehmanniae, Fructus Mori, Radix Polygalae, Rhizoma Picrorhizae, Rhizoma Polygonati Odorati, Herba Dendrobii, the Radix Paeoniae Alba, Fructus Chaenomelis and Mel are made; The Zinyin Bushen Pills perhaps be prepared from by Radix Angelicae Sinensis, Radix Rehmanniae Preparata, vinegar Carapax Et Plastrum Testudinis, Fructus Ligustri Lucidi, Herba Taxilli, Rhizoma Atractylodis Macrocephalae (parched), Colla cornus cervi, the Radix Astragali, Cortex Lycii, the Rhizoma Anemarrhenae, stir-baked CORTEX PHELLODENDRI with salt solution, Carapax Trionycis (processed with vinegar), Caulis Spatholobi, Rhizoma Dioscoreae, Herba Artemisiae Annuae, Radix Gentianae Macrophyllae, Radix Rehmanniae, Radix Polygalae, the Radix Paeoniae Alba and Fructus Chaenomelis.

Instructions of taking: 3 times on the one, a 9g, warm water delivery service; It within 30 days, is a course for the treatment of.

Criterion of therapeutical effect: according to " the new Chinese medicine guideline of clinical investigations " of Chinese Medicine science and technology office issue in 2002.Clinical cure: tcm clinical practice symptom, sign disappear or basic the disappearance, and the disease integration reduces >=95%.Produce effects: tcm clinical practice symptom, sign are obviously improved, and the disease integration reduces >=70%.Effectively: tcm clinical practice symptom, sign all take a favorable turn, and the disease integration reduces >=30%.Invalid: tcm clinical practice symptom, sign all are not improved, even increase the weight of, the disease integration reduces less than 30%.

Therapeutic outcome: treat 500 routine patients with ankylosing spondylitis, wherein cure 288 examples (accounting for 57.6%), produce effects 116 examples (accounting for 23.2%), effective 52 examples (accounting for 10.4%), invalid 44 examples (accounting for 8.8%), total effective rate reaches 91.2%.

Model case:

1, scape, the man, 32 years old, the Xinxiang City, Henan Province people, in June, 2009 is medical.Fall ill more than 20 years, lower pain in the lumbar region pain, limitation of activity; The X sheet shows bilateral II sacroiliitis, is diagnosed as " ankylosing spondylitis ".Take the enriching yin and nourishing kidney pill that the present invention treats ankylosing spondylitis, prescription is Radix Angelicae Sinensis 20g, Radix Rehmanniae Preparata 50g, vinegar Carapax Et Plastrum Testudinis 55g, Fructus Ligustri Lucidi 28g, Herba Taxilli 24g, Rhizoma Atractylodis Macrocephalae (parched) 46g, Colla cornus cervi 28g, Radix Astragali 50g, Cortex Lycii 38g, Rhizoma Anemarrhenae 26g, stir-baked CORTEX PHELLODENDRI with salt solution 18g, Carapax Trionycis (processed with vinegar) 55g, Caulis Spatholobi 48g, Rhizoma Dioscoreae 26g, Herba Artemisiae Annuae 42g, Radix Gentianae Macrophyllae 24g, Radix Rehmanniae 26g, Radix Polygalae 24g, Radix Paeoniae Alba 24g, Fructus Chaenomelis 18g, Fructus Lycii 48g, Radix Polygoni Multiflori Preparata 24g, Fructus Mori 24g, Rhizoma Polygonati Odorati 26g, Herba Dendrobii 24g, Rhizoma Cibotii 36g, Rhizoma Picrorhizae 20g and Radix Stellariae 42g; The pill instructions of taking: 3 times on the one, a 9g, warm water delivery service; It within 30 days, is a course for the treatment of.Take enriching yin and nourishing kidney pill for curing of the present invention and be clearly better after 2 courses for the treatment of, lumbago obviously alleviates, and the tcm symptom sign is obviously improved.Continue to take Zinyin Bushen Pills of the present invention after 2 courses for the treatment of symptom substantially disappear, take care of oneself, can participate in social activity and work and study, so far recurrence.

2, what, the female, 34 years old, Zhengzhou City Henan Province Zhongyuan District people, in March, 2007 is medical.Fall ill 6 years, the tired heavy stiff companion's pain in back, wear footgear can not, stretch movable difficulty after bending over, look into the X sheet and show that the bilateral sacroiliac joint meets mandatory spondylitis and changes.Take the enriching yin and nourishing kidney pill that the present invention treats ankylosing spondylitis, prescription is Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 40g, vinegar Carapax Et Plastrum Testudinis 40g, Fructus Ligustri Lucidi 20g, Herba Taxilli 18g, Rhizoma Atractylodis Macrocephalae (parched) 40g, Colla cornus cervi 24g, Radix Astragali 45g, Cortex Lycii 26g, Rhizoma Anemarrhenae 24g, stir-baked CORTEX PHELLODENDRI with salt solution 15g, Carapax Trionycis (processed with vinegar) 40g, Caulis Spatholobi 40g, Rhizoma Dioscoreae 20g, Herba Artemisiae Annuae 35g, Radix Gentianae Macrophyllae 16g, Radix Rehmanniae 20g, Radix Polygalae 20g, Radix Paeoniae Alba 18g, Fructus Chaenomelis 16g, Fructus Lycii 45g, Radix Polygoni Multiflori Preparata 20g, Fructus Mori 18g, Rhizoma Polygonati Odorati 20g, Herba Dendrobii 20g, Rhizoma Cibotii 35g, Rhizoma Picrorhizae 18g and Radix Stellariae 35g; Instructions of taking: 3 times on the one, a 9g, warm water delivery service, 30 days be a course for the treatment of.Take enriching yin and nourishing kidney pill for curing of the present invention and be clearly better after 2 courses for the treatment of, lumbago obviously alleviates, and the tcm symptom sign is obviously improved.Continue to take Zinyin Bushen Pills of the present invention after 2 courses for the treatment of symptom substantially disappear, can wear voluntarily footgear, the do-it-yourself class of bending over, now participated in daily life work.

3, Guo, the man, 23 years old, the Jinshui District people of Zhengzhou City, in February, 2007 is medical, fall ill more than 2 years, lumbago, pain after two hip activities, look into the pelvis ap sheet, the l spine ap & lat sheet shows: the sacroiliac joint gap disappears, the double hip joint narrow gaps, lumbar physiological-curvature disappears, little joint space is fuzzy, is diagnosed as " ankylosing spondylitis ".Take the enriching yin and nourishing kidney pill that the present invention treats ankylosing spondylitis, prescription is Radix Angelicae Sinensis 20g, Radix Rehmanniae Preparata 50g, vinegar Carapax Et Plastrum Testudinis 55g, Fructus Ligustri Lucidi 28g, Herba Taxilli 24g, Rhizoma Atractylodis Macrocephalae (parched) 46g, Colla cornus cervi 28g, Radix Astragali 50g, Cortex Lycii 38g, Rhizoma Anemarrhenae 26g, stir-baked CORTEX PHELLODENDRI with salt solution 18g, Carapax Trionycis (processed with vinegar) 55g, Caulis Spatholobi 48g, Rhizoma Dioscoreae 26g, Herba Artemisiae Annuae 42g, Radix Gentianae Macrophyllae 24g, Radix Rehmanniae 26g, Radix Polygalae 24g, Radix Paeoniae Alba 24g and Fructus Chaenomelis 18g; Instructions of taking: 3 times on the one, a 9g, warm water delivery service, 30 days be a course for the treatment of.Take enriching yin and nourishing kidney pill for curing of the present invention and be clearly better after 2 courses for the treatment of, lumbago obviously alleviates, and the tcm symptom sign is obviously improved.Continue to take Zinyin Bushen Pills of the present invention after 2 courses for the treatment of pain disappear, flexibly movable, now participate in daily life work.

4, Tan, the man, 31 years old, the Jiaozuo City people of Henan Province, in March, 2007 is medical, fall ill 5 years, sacroiliac discontinuity pain, the stiff sense in morning of companion's lower back, look into the pelvis ap sheet, the l spine ap & lat sheet shows: the bilateral sacroiliac joint is fuzzy, the double hip joint gap is narrow, and the small joints in lumbar spine gap owes clear, is diagnosed as " ankylosing spondylitis ".Take the enriching yin and nourishing kidney Chinese patent medicine pill that the present invention treats ankylosing spondylitis, prescription is Radix Angelicae Sinensis 25g, Radix Rehmanniae Preparata 55g, vinegar Carapax Et Plastrum Testudinis 60g, Fructus Ligustri Lucidi 30g, Herba Taxilli 28g, Rhizoma Atractylodis Macrocephalae (parched) 55g, Colla cornus cervi 40g, Radix Astragali 55g, Cortex Lycii 42g, Rhizoma Anemarrhenae 36g, stir-baked CORTEX PHELLODENDRI with salt solution 25g, Carapax Trionycis (processed with vinegar) 60g, Caulis Spatholobi 55g, Rhizoma Dioscoreae 30g, Herba Artemisiae Annuae 50g, Radix Gentianae Macrophyllae 28g, Radix Rehmanniae 28g, Radix Polygalae 26g, Radix Paeoniae Alba 25g, Fructus Chaenomelis 25g, Fructus Lycii 60g, Radix Polygoni Multiflori Preparata 30g, Fructus Mori 26g, Rhizoma Polygonati Odorati 28g, Herba Dendrobii 26g, Rhizoma Cibotii 55g, Rhizoma Picrorhizae 26g and Radix Stellariae 50g.Instructions of taking: 3 times on the one, a 9g, warm water delivery service; It within 30 days, is a course for the treatment of.Take enriching yin and nourishing kidney pill for curing of the present invention and be clearly better after 2 courses for the treatment of, waist and sacrum pain obviously alleviates, and the tcm symptom sign is obviously improved.Continue to take Zinyin Bushen Pills of the present invention after 2 courses for the treatment of symptom substantially disappear, take care of oneself, can participate in daily life work.

5, Wang, the man, 23 years old, Zhengzhou City Henan Province people from economic and technological development zone, in June, 2008 is medical.Fall ill 3 years, stiff sense in lower back morning, the two hip pain of companion, alleviate after activity, looks into the pelvis ap sheet, the l spine ap & lat sheet shows: lumbar vertebra physiology is bent degree and is disappeared, and straightens, and bilateral sacroiliac joint gap is fuzzy, and the small joints in lumbar spine gap owes clear.Be diagnosed as " ankylosing spondylitis ".Take the enriching yin and nourishing kidney pill that the present invention treats ankylosing spondylitis, prescription is Radix Angelicae Sinensis 20g, Radix Rehmanniae Preparata 45g, vinegar Carapax Et Plastrum Testudinis 46g, Fructus Ligustri Lucidi 25g, Herba Taxilli 22g, Rhizoma Atractylodis Macrocephalae (parched) 50g, Colla cornus cervi 35g, Radix Astragali 48g, Cortex Lycii 32g, Rhizoma Anemarrhenae 30g, stir-baked CORTEX PHELLODENDRI with salt solution 22g, Carapax Trionycis (processed with vinegar) 50g, Caulis Spatholobi 45g, Rhizoma Dioscoreae 28g, Herba Artemisiae Annuae 46g, Radix Gentianae Macrophyllae 20g, Radix Rehmanniae 23g, Radix Polygalae 22g, Radix Paeoniae Alba 20g and Fructus Chaenomelis 22g; Instructions of taking: 3 times on the one, a 9g, warm water delivery service; It within 30 days, is a course for the treatment of.Take enriching yin and nourishing kidney pill for curing of the present invention and be clearly better after 2 courses for the treatment of, two hip pain obviously alleviates, and lower back is flexibly movable, and the tcm symptom sign is obviously improved.Continue to take Chinese patent medicine of the present invention after 2 courses for the treatment of symptom substantially disappear, the study of now normally working.

The specific embodiment:

Further set forth the present invention below in conjunction with embodiment, but do not limit content of the present invention.

Embodiment 1:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills is prepared from by Radix Angelicae Sinensis 20g, Radix Rehmanniae Preparata 50g, vinegar Carapax Et Plastrum Testudinis 55g, Fructus Ligustri Lucidi 28g, Herba Taxilli 24g, Rhizoma Atractylodis Macrocephalae (parched) 46g, Colla cornus cervi 28g, Radix Astragali 50g, Cortex Lycii 38g, Rhizoma Anemarrhenae 26g, stir-baked CORTEX PHELLODENDRI with salt solution 18g, Carapax Trionycis (processed with vinegar) 55g, Caulis Spatholobi 48g, Rhizoma Dioscoreae 26g, Herba Artemisiae Annuae 42g, Radix Gentianae Macrophyllae 24g, Radix Rehmanniae 26g, Radix Polygalae 24g, Radix Paeoniae Alba 24g and Fructus Chaenomelis 18g by crude drug.

Embodiment 2:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills is prepared from by Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 40g, vinegar Carapax Et Plastrum Testudinis 40g, Fructus Ligustri Lucidi 20g, Herba Taxilli 18g, Rhizoma Atractylodis Macrocephalae (parched) 40g, Colla cornus cervi 24g, Radix Astragali 45g, Cortex Lycii 26g, Rhizoma Anemarrhenae 24g, stir-baked CORTEX PHELLODENDRI with salt solution 15g, Carapax Trionycis (processed with vinegar) 40g, Caulis Spatholobi 40g, Rhizoma Dioscoreae 20g, Herba Artemisiae Annuae 35g, Radix Gentianae Macrophyllae 16g, Radix Rehmanniae 20g, Radix Polygalae 20g, Radix Paeoniae Alba 18g and Fructus Chaenomelis 16g by crude drug.

Embodiment 3:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills is prepared from by Radix Angelicae Sinensis 25g, Radix Rehmanniae Preparata 55g, vinegar Carapax Et Plastrum Testudinis 60g, Fructus Ligustri Lucidi 30g, Herba Taxilli 28g, Rhizoma Atractylodis Macrocephalae (parched) 55g, Colla cornus cervi 40g, Radix Astragali 55g, Cortex Lycii 42g, Rhizoma Anemarrhenae 36g, stir-baked CORTEX PHELLODENDRI with salt solution 25g, Carapax Trionycis (processed with vinegar) 60g, Caulis Spatholobi 55g, Rhizoma Dioscoreae 30g, Herba Artemisiae Annuae 50g, Radix Gentianae Macrophyllae 28g, Radix Rehmanniae 28g, Radix Polygalae 26g, Radix Paeoniae Alba 25g and Fructus Chaenomelis 25g by crude drug.

Embodiment 4:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills is prepared from by Radix Angelicae Sinensis 22g, Radix Rehmanniae Preparata 45g, vinegar Carapax Et Plastrum Testudinis 46g, Fructus Ligustri Lucidi 25g, Herba Taxilli 22g, Rhizoma Atractylodis Macrocephalae (parched) 50g, Colla cornus cervi 35g, Radix Astragali 48g, Cortex Lycii 32g, Rhizoma Anemarrhenae 30g, stir-baked CORTEX PHELLODENDRI with salt solution 22g, Carapax Trionycis (processed with vinegar) 50g, Caulis Spatholobi 45g, Rhizoma Dioscoreae 28g, Herba Artemisiae Annuae 46g, Radix Gentianae Macrophyllae 20g, Radix Rehmanniae 23g, Radix Polygalae 22g, Radix Paeoniae Alba 20g and Fructus Chaenomelis 22g by crude drug.

Embodiment 5:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills is prepared from by Radix Angelicae Sinensis 18g, Radix Rehmanniae Preparata 48g, vinegar Carapax Et Plastrum Testudinis 50g, Fructus Ligustri Lucidi 23g, Herba Taxilli 26g, Rhizoma Atractylodis Macrocephalae (parched) 48g, Colla cornus cervi 32g, Radix Astragali 52g, Cortex Lycii 35g, Rhizoma Anemarrhenae 32g, stir-baked CORTEX PHELLODENDRI with salt solution 20g, Carapax Trionycis (processed with vinegar) 48g, Caulis Spatholobi 50g, Rhizoma Dioscoreae 24g, Herba Artemisiae Annuae 40g, Radix Gentianae Macrophyllae 22g, Radix Rehmanniae 25g, Radix Polygalae 25g, Radix Paeoniae Alba 22g and Fructus Chaenomelis 20g by crude drug.

Embodiment 6:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills by crude drug by Radix Angelicae Sinensis 20g, Radix Rehmanniae Preparata 50g, vinegar Carapax Et Plastrum Testudinis 55g, Fructus Ligustri Lucidi 28g, Herba Taxilli 24g, Rhizoma Atractylodis Macrocephalae (parched) 46g, Colla cornus cervi 28g, Radix Astragali 50g, Cortex Lycii 38g, Rhizoma Anemarrhenae 26g, stir-baked CORTEX PHELLODENDRI with salt solution 18g, Carapax Trionycis (processed with vinegar) 55g, Caulis Spatholobi 48g, Rhizoma Dioscoreae 26g, Herba Artemisiae Annuae 42g, Radix Gentianae Macrophyllae 24g, Radix Rehmanniae 26g, Radix Polygalae 24g, Radix Paeoniae Alba 24g, Fructus Chaenomelis 18g, Fructus Lycii 48g, Radix Polygoni Multiflori Preparata 24g, Fructus Mori 24g, Rhizoma Polygonati Odorati 26g, Herba Dendrobii 24g, Rhizoma Cibotii 36g, Rhizoma Picrorhizae 20g and Radix Stellariae 42g are prepared from.

Embodiment 7:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills by crude drug by Radix Angelicae Sinensis 15g, Radix Rehmanniae Preparata 40g, vinegar Carapax Et Plastrum Testudinis 40g, Fructus Ligustri Lucidi 20g, Herba Taxilli 18g, Rhizoma Atractylodis Macrocephalae (parched) 40g, Colla cornus cervi 24g, Radix Astragali 45g, Cortex Lycii 26g, Rhizoma Anemarrhenae 24g, stir-baked CORTEX PHELLODENDRI with salt solution 15g, Carapax Trionycis (processed with vinegar) 40g, Caulis Spatholobi 40g, Rhizoma Dioscoreae 20g, Herba Artemisiae Annuae 35g, Radix Gentianae Macrophyllae 16g, Radix Rehmanniae 20g, Radix Polygalae 20g, Radix Paeoniae Alba 18g, Fructus Chaenomelis 16g, Fructus Lycii 45g, Radix Polygoni Multiflori Preparata 20g, Fructus Mori 18g, Rhizoma Polygonati Odorati 20g, Herba Dendrobii 20g, Rhizoma Cibotii 35g, Rhizoma Picrorhizae 18g and Radix Stellariae 35g are prepared from.

Embodiment 8:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills by crude drug by Radix Angelicae Sinensis 25g, Radix Rehmanniae Preparata 55g, vinegar Carapax Et Plastrum Testudinis 60g, Fructus Ligustri Lucidi 30g, Herba Taxilli 28g, Rhizoma Atractylodis Macrocephalae (parched) 55g, Colla cornus cervi 40g, Radix Astragali 55g, Cortex Lycii 42g, Rhizoma Anemarrhenae 36g, stir-baked CORTEX PHELLODENDRI with salt solution 25g, Carapax Trionycis (processed with vinegar) 60g, Caulis Spatholobi 55g, Rhizoma Dioscoreae 30g, Herba Artemisiae Annuae 50g, Radix Gentianae Macrophyllae 28g, Radix Rehmanniae 28g, Radix Polygalae 26g, Radix Paeoniae Alba 25g, Fructus Chaenomelis 25g, Fructus Lycii 60g, Radix Polygoni Multiflori Preparata 30g, Fructus Mori 26g, Rhizoma Polygonati Odorati 28g, Herba Dendrobii 26g, Rhizoma Cibotii 55g, Rhizoma Picrorhizae 26g and Radix Stellariae 50g are prepared from.

Embodiment 9:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills by crude drug by Radix Angelicae Sinensis 22g, Radix Rehmanniae Preparata 45g, vinegar Carapax Et Plastrum Testudinis 46g, Fructus Ligustri Lucidi 25g, Herba Taxilli 22g, Rhizoma Atractylodis Macrocephalae (parched) 50g, Colla cornus cervi 35g, Radix Astragali 48g, Cortex Lycii 32g, Rhizoma Anemarrhenae 30g, stir-baked CORTEX PHELLODENDRI with salt solution 22g, Carapax Trionycis (processed with vinegar) 50g, Caulis Spatholobi 45g, Rhizoma Dioscoreae 28g, Herba Artemisiae Annuae 46g, Radix Gentianae Macrophyllae 20g, Radix Rehmanniae 23g, Radix Polygalae 22g, Radix Paeoniae Alba 20g, Fructus Chaenomelis 22g, Fructus Lycii 52g, Radix Polygoni Multiflori Preparata 28g, Fructus Mori 22g, Rhizoma Polygonati Odorati 22g, Herba Dendrobii 22g, Rhizoma Cibotii 45g, Rhizoma Picrorhizae 24g and Radix Stellariae 46g are prepared from.

Embodiment 10:

The present invention treats the Zinyin Bushen Pills of ankylosing spondylitis, with weight portion, mean, described Zinyin Bushen Pills by crude drug by Radix Angelicae Sinensis 18g, Radix Rehmanniae Preparata 48g, vinegar Carapax Et Plastrum Testudinis 50g, Fructus Ligustri Lucidi 23g, Herba Taxilli 26g, Rhizoma Atractylodis Macrocephalae (parched) 48g, Colla cornus cervi 32g, Radix Astragali 52g, Cortex Lycii 35g, Rhizoma Anemarrhenae 32g, stir-baked CORTEX PHELLODENDRI with salt solution 20g, Carapax Trionycis (processed with vinegar) 48g, Caulis Spatholobi 50g, Rhizoma Dioscoreae 24g, Herba Artemisiae Annuae 40g, Radix Gentianae Macrophyllae 22g, Radix Rehmanniae 25g, Radix Polygalae 25g, Radix Paeoniae Alba 22g, Fructus Chaenomelis 20g, Fructus Lycii 55g, Radix Polygoni Multiflori Preparata 26g, Fructus Mori 20g, Rhizoma Polygonati Odorati 24g, Herba Dendrobii 23g, Rhizoma Cibotii 48g, Rhizoma Picrorhizae 22g and Radix Stellariae 40g are prepared from.

The preparation method of the Zinyin Bushen Pills of the described treatment ankylosing spondylitis of above-described embodiment 1-10:

At first the proportioning ratio according to the enriching yin and nourishing kidney Chinese patent medicine of the described treatment ankylosing spondylitis of above-mentioned arbitrary embodiment takes various crude drug, the various crude drug that take are pulverized respectively, cross 100 mesh sieves, by the various crude drug medicated powder mix homogeneously after pulverizing, obtain mixing fine powders, then according to every 100g mixing fine powders, add the ratio of starch 2g to add the starch mix homogeneously, after mixing, according to every 100g mixing fine powders, add refined honey 10～20g to add refined honey, and add water 40g to add required water according to every 100g mixing fine powders, make pill according to conventional method, finally carry out successively drying, bag charcoal clothing, the Pulvis Talci polishing, obtain the Zinyin Bushen Pills of product treatment ankylosing spondylitis.

Claims (5)

1. a Zinyin Bushen Pills for the treatment of ankylosing spondylitis, it is characterized in that: with weight portion, mean, described Zinyin Bushen Pills is by 15～25 parts of crude drug Radix Angelicae Sinensis, 40～55 parts of Radix Rehmanniae Preparata, 40～60 parts of vinegar Carapax Et Plastrum Testudiniss, 20～30 parts of Fructus Ligustri Lucidi, 18～28 parts of Herba Taxillis, 40～55 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 24～40 parts of Colla cornus cervis, 45～55 parts of the Radixs Astragali, 26～42 parts of Cortex Lycii, 24～36 parts of the Rhizoma Anemarrhenaes, 15～25 parts of stir-baked CORTEX PHELLODENDRI with salt solution, 40～60 parts of Carapax Trionycis (processed with vinegar), 40～55 parts of Caulis Spatholobis, 20～30 parts of Rhizoma Dioscoreaes, 35～50 parts of Herba Artemisiae Annuaes, 16～28 parts of Radix Gentianae Macrophyllae, 20～28 parts of Radix Rehmanniae, 20～26 parts of Radix Polygalaes, 16～25 parts of 18～25 parts of the Radix Paeoniae Albas and Fructus Chaenomeliss are prepared from.

2. the Zinyin Bushen Pills for the treatment of ankylosing spondylitis according to claim 1, it is characterized in that: described Zinyin Bushen Pills is by 18～22 parts of crude drug Radix Angelicae Sinensis, 45～50 parts of Radix Rehmanniae Preparata, 45～55 parts of vinegar Carapax Et Plastrum Testudiniss, 23～28 parts of Fructus Ligustri Lucidi, 22～26 parts of Herba Taxillis, 45～50 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 26～32 parts of Colla cornus cervis, 48～52 parts of the Radixs Astragali, 30～38 parts of Cortex Lycii, 26～32 parts of the Rhizoma Anemarrhenaes, 18～22 parts of stir-baked CORTEX PHELLODENDRI with salt solution, 45～55 parts of Carapax Trionycis (processed with vinegar), 45～50 parts of Caulis Spatholobis, 23～28 parts of Rhizoma Dioscoreaes, 40～45 parts of Herba Artemisiae Annuaes, 20～26 parts of Radix Gentianae Macrophyllae, 24～27 parts of Radix Rehmanniae, 22～25 parts of Radix Polygalaes, 18～22 parts of 20～24 parts of the Radix Paeoniae Albas and Fructus Chaenomeliss are prepared from.

3. a Zinyin Bushen Pills for the treatment of ankylosing spondylitis, it is characterized in that: with weight portion, mean, described Zinyin Bushen Pills is by 15～25 parts of crude drug Radix Angelicae Sinensis, 40～55 parts of Radix Rehmanniae Preparata, 40～60 parts of vinegar Carapax Et Plastrum Testudiniss, 20～30 parts of Fructus Ligustri Lucidi, 18～28 parts of Herba Taxillis, 40～55 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 24～40 parts of Colla cornus cervis, 45～55 parts of the Radixs Astragali, 26～42 parts of Cortex Lycii, 24～36 parts of the Rhizoma Anemarrhenaes, 15～25 parts of stir-baked CORTEX PHELLODENDRI with salt solution, 40～60 parts of Carapax Trionycis (processed with vinegar), 40～55 parts of Caulis Spatholobis, 20～30 parts of Rhizoma Dioscoreaes, 35～50 parts of Herba Artemisiae Annuaes, 16～28 parts of Radix Gentianae Macrophyllae, 20～28 parts of Radix Rehmanniae, 20～26 parts of Radix Polygalaes, 18～25 parts of the Radix Paeoniae Albas, 16～25 parts of Fructus Chaenomeliss, 45～60 parts of Fructus Lycii, 20～30 parts of Radix Polygoni Multiflori Preparatas, 18～26 parts, Fructus Mori, 20～28 parts of Rhizoma Polygonati Odorati, 20～26 parts of Herba Dendrobiis, 35～55 parts of Rhizoma Cibotii, 35～50 parts of 18～26 parts of Rhizoma Picrorhizae and Radix Stellariaes are prepared from.

4. the Zinyin Bushen Pills for the treatment of ankylosing spondylitis according to claim 3, it is characterized in that: described Zinyin Bushen Pills is by 18～22 parts of crude drug Radix Angelicae Sinensis, 45～50 parts of Radix Rehmanniae Preparata, 45～55 parts of vinegar Carapax Et Plastrum Testudiniss, 23～28 parts of Fructus Ligustri Lucidi, 22～26 parts of Herba Taxillis, 45～50 parts of Rhizoma Atractylodis Macrocephalae (parched)s, 26～32 parts of Colla cornus cervis, 48～52 parts of the Radixs Astragali, 30～38 parts of Cortex Lycii, 26～32 parts of the Rhizoma Anemarrhenaes, 18～22 parts of stir-baked CORTEX PHELLODENDRI with salt solution, 45～55 parts of Carapax Trionycis (processed with vinegar), 45～50 parts of Caulis Spatholobis, 23～28 parts of Rhizoma Dioscoreaes, 40～45 parts of Herba Artemisiae Annuaes, 20～26 parts of Radix Gentianae Macrophyllae, 24～27 parts of Radix Rehmanniae, 22～25 parts of Radix Polygalaes, 20～24 parts of the Radix Paeoniae Albas, 18～22 parts of Fructus Chaenomeliss, 48～55 parts of Fructus Lycii, 23～27 parts of Radix Polygoni Multiflori Preparatas, 20～25 parts, Fructus Mori, 23～27 parts of Rhizoma Polygonati Odorati, 22～25 parts of Herba Dendrobiis, 36～45 parts of Rhizoma Cibotii, 40～45 parts of 20～24 parts of Rhizoma Picrorhizae and Radix Stellariaes are prepared from.

5. according to the Zinyin Bushen Pills of the described treatment ankylosing spondylitis of claim 1～4 any one, it is characterized in that, the preparation method of described Zinyin Bushen Pills is:

At first the proportioning ratio according to the Zinyin Bushen Pills of the described treatment ankylosing spondylitis of claim 1～4 any one takes various crude drug, the various crude drug that take are pulverized respectively, cross 100 mesh sieves, by the various crude drug medicated powder mix homogeneously after pulverizing, obtain mixing fine powders, then according to every 100g mixing fine powders, add the ratio of starch 2g to add the starch mix homogeneously, after mixing, according to every 100g mixing fine powders, add the ratio of refined honey 10～20g to add refined honey, and add the ratio of water 40g to add required water according to every 100g mixing fine powders, then make pill according to conventional method, finally carry out successively drying, bag charcoal clothing, the Pulvis Talci polishing, obtain the Zinyin Bushen Pills of product treatment ankylosing spondylitis.