CN1211103C - Oral taken and external use medicine for antirheumatism and stopping numbness pain - Google Patents

Oral taken and external use medicine for antirheumatism and stopping numbness pain Download PDF

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CN1211103C
CN1211103C CNB021019681A CN02101968A CN1211103C CN 1211103 C CN1211103 C CN 1211103C CN B021019681 A CNB021019681 A CN B021019681A CN 02101968 A CN02101968 A CN 02101968A CN 1211103 C CN1211103 C CN 1211103C
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radix
medicine
radix aconiti
rhizoma
external use
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CN1433787A (en
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马献山
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Abstract

The present invention provides a medicine for oral administration and external application for dispelling rheumatism and resisting arthralgia, which is a pure traditional Chinese medicine preparation without toxic or side effects and aims to increase cure rates. The medicine for oral administration is mainly prepared from 47 Chinese herbal medicines of clematis root, honeysuckle stem, radix angelicae tuhuo, etc., and the external application medicine is prepared from 13 Chinese herbal medicines of shortstalk monkshood root, anisodus luridus, etc. The medicine for oral administration is prepared by taking a proportion dosage of pure dry Chinese herbal medicines, grinding the pure dry Chinese herbal medicines into fine powder, disinfecting the fine powder and loading 0.75 gram of the fine powder into a capsule; the external medicine is prepared by pouring pure sesame oil into a pot to be decocted dryly, pouring 9 kinds of thick medicine powder to the pot to be decocted again, filtrating the decoction, adding yellow lead to the filtrate to be decocted, adding the other two medicines to the decoction and uniformly stirring the decoction. The medicine of the present invention has obvious therapeutic effects on the treatment for rheumatoid arthritis, rheumatoild diseases, ankylosing spondylitis, sciatica, rheumatic and cold arthritis, hyperplasy of the cervical vertebrae and lumbar vertebrae, hyperosteogeny of the other positions, periarthritis of the shoulders, numbness of the limbs, traumatic injuries, etc. through the functions of dispelling wind, eliminating dampness, activating blood circulation to dissipate blood stasis, expelling wind, clearing away cold, stopping wind, regulating the balance of yin and yang and enhancing the immune functions of human bodies.

Description

For oral administration, the medicine for external use of a kind of wind-damp dispelling, stopping numbness pain and preparation method
The present invention relates to a kind of can wind-damp dispelling, end the oral medicine (also claiming " stretch muscle and chase after the wind capsule "), medicine for external use (also claim " stretching muscle chases after wind and paste) of numbness disease, composition of more particularly a kind of wind-damp dispelling, stopping numbness pain oral medicine, medicine for external use and its production and application method.
In background technology, the traditional Chinese medical science is to the exploration of rheumatism, arthralgia pain, origin for a long time, ancient Chinese medicine doctor has accumulated rich experience, has summed up the oral medicine or the medicine for external use of many wind-damp dispelling, stopping numbness pain, all be to use separately separately, for oral administration, otherwise external, as: in practice, these medicines respectively have the treatment characteristics, but all do not reach ideal therapeutic effect.
The objective of the invention is to develop for oral administration of a kind of wind-damp dispelling, stopping numbness pain, medicine for external use; The consumption proportion method of oral medicine of research and development wind-damp dispelling, stopping numbness pain (also claiming " stretch muscle and chase after the wind capsule ") and medicine for external use (also claiming " stretch muscle and chase after the wind subsides "); Research wind-damp dispelling, the oral medicine of stopping numbness pain and the preparation method of medicine for external use; The application process of research wind-damp dispelling, stopping numbness pain oral medicine and medicine for external use finally reaches ideal therapeutic effect.
The inventor thinks in secular tcm clinical practice practice: the etiology and pathogenesis of arthralgia pain: its exopathogenic factor is because the place, residence is moist, paddles in spite of the rain weather drastic change, cold and hot reason such as staggered, thus wind-cold damp pathogen attacks human body in an opponent's defence, injects meridians, stay in the joint, make QI and blood numbness resistance and fall ill, endogenous cause of ill is an intrinsic factor body weakness, positive QI-insufficiency, interspaces of skin and muscles being loose, weakened defensive QI, closely related with blood stasis again, arthromyodynia is often lasted longer, repeatedly outbreak, the ankylosis distortion, very then juxtra-articular is the darkness color, sharp ache, unable to flex and stretch the extremities or pain numbness, or the joint is cold and cool, meet the change of gas friendship, cold season, then pain was acute, got Re Zean, all because of arthromyodynia with the passing of time, meridian qi and blood is that exopathogen stop up to stagnate, and moves unfavorable and to lead to blood stasis expectorant turbid, and the stasis of blood chronic knot root that stagnates in the joint is dark, being difficult to beneficial another name for Sichuan Province removes, the expectorant stasis of blood is knot, and the numbness resistance increases the weight of, so sharp ache, QI and blood is current not smooth, so see numbness; The expectorant stasis of blood is kept, so localized pain; The purple dark blackout of juxtra-articular, also levying for stagnation of QI-blood.
Technical solution of the present invention is as follows
For oral administration, the medicine for external use of a kind of wind-damp dispelling, stopping numbness pain, it is characterized in that: the herbal raw material by following portions by weight is made:
Oral medicine:
Radix Clematidis: 5-15 Fen ， Herba Siegesbeckiae: 5-15 part, Caulis Lonicerae: 5-15 part,
Rhizoma Et Radix Notopterygii: 2-12 part, Radix Angelicae Pubescentis: 2-12 part, the Rhizoma Atractylodis Macrocephalae: 2-12 part,
Radix Angelicae Sinensis: 1-10 part, Radix Rehmanniae Preparata: 1-10 part, Radix Ginseng: 1-10 part,
The Radix Astragali: 5-15 part, Rhizoma Gastrodiae: 1-12 part, Herba Taxilli: 2-12 part,
Herba Ephedrae: 1-10 part, Herba Asari: 0.4-4 part, Olibanum: 2-12 part,
Myrrha: 2-12 part, the Cortex Eucommiae: 2-12 part, Rhizoma Drynariae: 0.4-4 part,
Radix Aconiti Preparata: 1-10 part, Radix Aconiti Kusnezoffii Preparata: 1-10 part, Radix Aconiti Lateralis Preparata: 0.4-4 part,
Semen Strychni (processed): 0.4-4 part, Agkistrodon: 2-12 part, Zaocys: 2-12 part,
Pheretima: 2-12 part, Scolopendra: 1-10 part, Scorpio: 1-10 part,
Process Catharsii molossi: 1-10 part, process the worm: 1-10 part, Formica fusca: 5-15 part,
Squama Manis (processed): 0.4-4 part, Bombyx Batryticatus: 1-10 part, Rhizoma Coptidis: 0.6-6 part,
Cortex Phellodendri: 0.6-6 part, Radix Scutellariae: 0.6-6 part, Radix et Rhizoma Rhei (processed with wine): 0.6-6 part,
Rhizoma Anemones Raddeanae: 0.5-5 part, Rhizoma Chuanxiong: 2-12 part, the Radix Aucklandiae: 0.4-4 part,,
Lignum Aquilariae Resinatum: 0.4-4 part, Flos Caryophylli: 0.4-4 part, Rhizoma Cyperi: 0.4-4 part,
Radix Puerariae: 2-12 part, Cornu Bubali: 2-12 part, Cortex Moutan: 1-10 part,
Radix Glycyrrhizae Preparata: 2-12 part, Radix Scrophulariae: 0.4-4 part;
Medicine for external use:
Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani): 5-20 part, Radix Anisodi Acutanguli: 5-15 part; Semen Strychni: 3-12 part,
White imperial rattan: 3-12 part, Radix aconiti hemsleyani: 5-15 part, Radix aconiti szechenyiani: 3-12 part,
Semen Sinapis Albae: 10-30 part, Mylabris: 0.1-0.4 part, Squama Manis: 3-12 part,
Radix Clematidis: 10-20 part, Semen Impatientis: 10-20 part, Plumbum preparatium: 1000-1250 part,
Sesame oil: 2000-3000 part.
Make the manufacturing technique method of for oral administration, the medicine for external use of described a kind of wind-damp dispelling, stopping numbness pain, it is characterized in that:
The manufacture method of oral medicine in turn includes the following steps:
Get the Chinese herbal medicine above-mentioned for oral administration of clean dry, be milled to fine powder respectively or after mixing by above-mentioned deal proportioning, can cross 240 mesh sieves, behind the uniform mixing, ultraviolet and/or 〉=sterilize under 100 ℃ of high temperature, per 0.75 gram fine powder Chinese herbal medicine of weighing is loaded on " 0 " number capsule, whenever bottledly goes into 100 capsules and gets final product through checking.
The manufacture method of medicine for external use in turn includes the following steps:
1. get the above-mentioned Chinese herbal medicine for external use of clean dry, respectively or together Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Radix Anisodi Acutanguli, Semen Strychni, Bai Longteng, Radix aconiti hemsleyani, Radix aconiti szechenyiani, Semen Sinapis Albae, Semen Impatientis, nine kinds of Chinese herbal medicine powders of Radix Clematidis are broken into coarse powder by above-mentioned deal proportioning, Mylabris, Squama Manis are milled to fine powder, can cross 240 mesh sieves;
2. sesame oil is poured in the pot, endured out, nine kinds of coarse powder Chinese herbal medicine mix homogeneously in above-mentioned the 1st step with low baking temperature, pour in the pot, enduring black is degree, filters clean medicinal residues with cotton yarn, reenters clean pot, low baking temperature is endured to dripping and is not loose, the Plumbum preparatium that adds above-mentioned deal is endured to dripping into pearl from fire with slow fire, waits the medicine temperature drop to 90-100 ℃, above-mentioned deal is milled to Mylabris, the Squama Manis mixing of fine powder, pours in the pot and stir evenly;
3. be spread out on the cloth, outside reuse paper bag installs, and with the plastic pocket sealing, preserves stand-by;
4. get the external-applied ointment that is spread out in the pocket on the cloth and be placed on circular patch or the paster, 20 grams are put in every subsides, spread out thick 0.2-0.4 centimetre, and diameter 8-10 centimetre, be folded into semicircle the subsides, packing inspection gets final product.
For oral administration, the medicine for external use of described wind-damp dispelling, stopping numbness pain, it is characterized in that: the parts by weight of raw material following Chinese medicinal herb raw wherein also can be made up of following proportioning:
Oral medicine:
Herba Asari: 0.4-2 part, Radix Aconiti Preparata: 1-8 part, Radix Aconiti Kusnezoffii Preparata: 1-8 part,
Semen Strychni (processed): 1-6 part, Agkistrodon: 2-8 part, Zaocys: 2-8 part,
Pheretima: 2-8 part, Scolopendra: 1-8 part, Scorpio: 1-8 part,
Process Catharsii molossi: 1-8 part, process the worm: 1-8 part, Bombyx Batryticatus: 1-4 part,
Rhizoma Anemones Raddeanae: 0.5-6 part;
Medicine for external use:
Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani): 5-10 part, Radix Anisodi Acutanguli: 5-10 part, Bai Longteng: 3-6 part,
Radix aconiti hemsleyani: 5-10 part, Squama Manis: 3-6 part, Radix Clematidis: 5-10 part,
Semen Impatientis: 5-10 part, Mylabris: 0.1-0.2 part.
Advantage of the present invention and effect are as follows:
1, owing to adopts 47 kinds of Chinese herbal medicine of oral medicine, 12 kinds of Chinese herbal medicine of medicine for external use (also have effective proportioning of sesame oil and use in addition, so using that the patient is for oral administration can blood circulation promoting and blood stasis dispelling, balance regulating YIN and YANG QI and blood, expelling wind and removing dampness, external can blood circulation promoting and blood stasis dispelling, ease pain, search the wind damp eliminating, reducing swelling and alleviating pain, the dissipating blood stasis of drawing out pus by applying a plaster to the affected part hemostasis.
2, owing to adopt the method for treatment by oral administration of medicines and the dialectical combination of external treatment, so make the patient in the short period of time, through several course of therapy, can access effective healing, has expelling wind and dampness, blood circulation promoting and blood stasis dispelling, the effect of stopping numbness pain, to rheumatic arthritis, rheumatoid arthritis, ankylosing spondylitis, cervical vertebra pain, hyperosteogeny, scapulohumeral periarthritis, osteoarthritis, sciatica, rheumatic fever etc. have the obvious treatment effect and have produced the unexpected curative effect of not putting down in writing for prior art, through clinical nearly thousand example checkings, the rheumatism arthritis total effective rate is reached 99%, cure rate 87.6%.
3, adopt clinical treatment rheumatoid arthritis 105 examples of the present invention; Wherein male 20 examples, 85 example age 24-65 years of woman, 44.1 years old mean age; Fell ill 6.5 months time to 30.5;
Diagnostic criteria: carry out according to the rheumatoid disease diagnostic criteria that 1987 (health ministry) revised.The laboratory: patient's rheumatoid factor is all positive, and titre is greater than more than 1: 32, and erythrocyte sedimentation rate all speeds; X-ray film: the patient has more increasing property osteoporosis in various degree, degeneration, and subluxation, the little and bone erosion in joint space, articular cartilage disappears.
Therapeutic Method: each 8 of oral medicine, quite crude drug 6 restrains 3 times on the one; Medicine for external use pastes 10 at every turn and pastes, and has both gone up wrist, elbow, shoulder, lower limb knee joint, ankle joint, whenever puts up 10 days, and 10 days is a course of treatment.
The result observes: cure 92 examples, reach 87.6%: clinical symptom disappearance, and the limbs profile is normal, and function is good, recovers work, the chemical examination rheumatoid factor negative.
12 examples that take a turn for the better reach 11.4%: transference cure, can participate in slight work, the chemical examination rheumatoid factor negative.
Invalid 1 example accounts for 0.9%: before and after the treatment, and symptom and sign and rheumatoid factor no change.
In conjunction with above-mentioned three grades of efficacy determinations, total effective rate reaches 99%.
4, adopt the present invention to treat cervical spondylosis patient 405 examples, wherein male: 210 examples, women: 195 examples, age 30-65 year, the course of disease 50 days to 12 years;
Diagnostic criteria: X line, CT, MIR check and clinical manifestation, restriction of neck motion, and upper limb numbness supraspinatus, triangular muscle pain, headache, dizziness, the Huffman positive have zonesthesia etc.
Therapeutic Method: oral medicine is obeyed 8 at every turn, treats statistics after 60 days every day 3 times, and pasted 10 days at every turn at external plaster hypertrophy position, and 10 days is a course of treatment.
Treatment efficacy determination result:
395 examples of fully recovering, account for 94.8%: the cervical region movable function is normal, and pain disappears, and upper limb numbness and sign disappear, headache, the dizzy disappearance.
Produce effects 5 examples: account for 1.2%: movable function is near normal, and dizzy, headache disappears, cervical pain, and upper limb numbness disappears substantially.
3 examples that take a turn for the better, account for 0.47%: cervical pain alleviates, and sign and upper limb numbness exist, and cervical region is movable autonomous.
Invalid 7 examples account for 3.26%: no change before and after the treatment
In conjunction with above-mentioned level Four efficacy determination, total effective rate reaches 96.44%.
5, adopt the present invention to treat scapulohumeral periarthritis patient 105 examples, wherein male: 40 examples, women: 65 examples, age 35-65 year, 50 years old mean age, 1 year 6 months time of falling ill;
Therapeutic Method: without oral medicine, adopt medicine for external use of the present invention, pasted once in 10 days, 10 days is a course of treatment, and the sealing of Daphne giraldii Nitsche injection liquid Tiaokou cave adds functional exercise, treats three courses of treatment and adds up.
The treatment curative effect determinate standard:
Cure 105 examples: the shoulder joint movable function is normal:
Effective 0 example: the shoulder joint activity makes moderate progress;
Invalid 0 example: no change before and after the treatment.
Above-mentioned total effective rate reaches 100%.
Embodiments of the invention are described as follows: it is as follows to get the herbal raw material proportioning:
Oral medicine
Chinese herbal medicine 1 group 2 groups 3 groups 4 groups 5 groups 6 groups 7 groups 8 groups 9 groups 10 groups
Radix Clematidis 5 6 7 9 10 11 12 13 14 15
Herba Siegesbeckiae 5 7 8 9 10 11 12 3 14 15
Caulis Lonicerae 15 14 13 12 10 9 8 7 6 5
Rhizoma Et Radix Notopterygii 12 10 8 6 5 7 6 5 3 2
Radix Angelicae Pubescentis 2 4 5 6 7 8 9 10 11 12
The Rhizoma Atractylodis Macrocephalae 12 11 9 8 7 6 5 4 3 2
Radix Angelicae Sinensis 1 2 3 4 5 6 7 8 9 10
Radix Rehmanniae Preparata 10 9 8 7 6 5 4 3 2 1
Radix Ginseng 1 2 3 4 5 6 7 8 9 10
The Radix Astragali 15 14 13 12 11 10 9 8 7 5
Rhizoma Gastrodiae 2 3 5 6 7 8 9 10 11 12
Herba Taxilli 12 11 10 9 8 7 6 5 3 2
Herba Ephedrae 1 2 3 4 5 6 7 8 9 10
Herba Asari 0.4 0.8 1.0 1.8 2 2.5 3 3.2 3.6 4
Olibanum 12 10 9 8 7 6 5 4 3 2
Myrrha 2 4 3 6 7 8 9 10 11 12
The Cortex Eucommiae 12 10 9 8 7 6 5 4 3 2
Rhizoma Drynariae 4 3.5 3 2.5 2 2.8 2.0 1.5 1 0.4
Radix Aconiti Preparata 1 2 3 4 5 6 7 8 9 10
Radix Aconiti Kusnezoffii Preparata 10 9 8 7 6 5 4 3 2 1
Radix Aconiti Lateralis Preparata 4 3.5 3 2.5 2 1.5 1.2 1.0 0.8 0.4
Semen Strychni (processed) 0.4 0.1 1.4 2 2.4 2.8 3 3.2 3.5 4
Agkistrodon 12 11 10 9 8 7 6 5 4 2
Zaocys 2 3 5 6 7 8 9 6 11 12.3
Pheretima 12 11 10 9 8 7 6 5 4 2
Scolopendra 1 2 3 4 5 6 7 8 9 10.3
Scorpio 10 9 8 7 6.5 5 4 3 2 1
Process the Qiang dung beetle 1 2.5 3 4 5.5 6 7 8 9 10
Process the worm 10 9 8 7 6.5 5 4 3 2 1.2
Formica fusca 5 7 8 9 10 11 12 11 14 15
Squama Manis (processed) 0.4 1 1.2 1.8 2 2.5 2.8 3 3.5 4
Bombyx Batryticatus 1 2 3 4 5.4 6 7 7.8 9 10
Rhizoma Coptidis 6.2 5.3 5 4.5 4 3.5 3 2.5 1 0.6
Cortex Phellodendri 0.6 1 1.2 2 2.5 3 3.5 4 4.5 6
Radix Scutellariae 6.2 5.5 4 3.5 3 2.5 2 1.5 1 0.6
Radix et Rhizoma Rhei (processed with wine) 6 1 1.5 2 2.5 3 3.5 4 4.5 6
Rhizoma Anemones Raddeanae 1 6 6 7 5.5 6 2 3 4.2 10
Rhizoma Chuanxiong 12 10 9 8 7.5 6 5 4 3 2
The Radix Aucklandiae 0.4 0.8 1.0 1.5 2.0 2.5 3.0 3.2 3.8 4
Lignum Aquilariae Resinatum 4 3.5 3 2.5 2.2 2 1.8 1.2 1 0.4
Flos Caryophylli 0.4 1 1.2 1.8 2 2.5 3 3.5 3.8 4
Rhizoma Cyperi 4 3.5 3 3.6 3 2.5 2.0 1.5 1 0.4
Radix Puerariae 2 8 7 6 7 4.4 9 5.4 11 12
Cornu Bubali 12 11 10 9 8 7 6 5 4 2
Cortex Moutan 1 2 6 4 5 6 7 8 9 10
Radix Glycyrrhizae Preparata 12 11 10 9 8 7 6 5 4 2
Radix Scrophulariae 4 1 1.5 2 2.5 3 3.2 3.5 3.8 0.4
Amount to 265 265 265 265 265 265 265 265 265 265
Medicine for external use
Chinese herbal medicine 1 group 2 groups 3 groups 4 groups 5 groups 6 groups 7 groups 8 groups 9 groups 10 groups
Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani) 5 7 9 11 12 13 15 16 18 20
Radix Anisodi Acutanguli 15 13 12 11 10 9 8 7 6 5
Semen Strychni 3 4 5 6 7 8 9 10 11 12
White imperial rattan 12 11 10 9 8 7 6 5 4 3
Radix aconiti hemsleyani 5 6 7 8 9 10 11 12 13 15
Radix aconiti szechenyiani 12 11 10 9 8 7 6 5 4 3
Semen Sinapis Albae 10 12 15 18 20 22 24 26 28 30
Mylabris 0.1 0.2 0.3 0.4 0.4 0.3 0.2 0.1 0.2 0.1
Squama Manis 12 11 10 9 8 7 6 5 4 3
Radix Clematidis 20 18 17 16 15 14 13 12 11 10
Semen Impatientis 10 11 12 13 14 15 16 17 18 20
Plumbum preparatium 1000 1050 1100 1150 1200 1050 1100 1150 1200 1250
Sesame oil 2495.9 2445.8 2392.7 2339.6 2288.6 2437.7 2385.8 2334.9 2282.8 2228.9
Amount to 3600 3600 3600 3600 3600 3600 3600 3600 3600 3600
The method for making of oral medicine is as follows:
The pure medical material of getting above-mentioned ten groups of consumptions is at 30-70 ℃ or dry under 40-50 ℃ of environment, perhaps ten groups of said ratio consumptions will be got behind the above-mentioned pure medicinal material drying, with the gram is unit, is milled to fine powder then, crosses 240 mesh sieves, under ℃ condition of high temperature 〉=100, sterilize, or under ultraviolet, sterilize, mix homogeneously, ten groups are respectively total 265 grams, per 0.75 gram fine powder Chinese herbal medicine of weighing respectively is loaded on " 0 " number capsule, whenever bottledly goes into 100 capsules promptly through checking.
The manufacture method of medicine for external use in turn includes the following steps:
1, getting above-mentioned ten groups of clean dry is the Chinese herbal medicine for external use of unit with the gram, drying means is the same, every group of deal proportioning by medicine for external use is broken into coarse powder with Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Radix Anisodi Acutanguli, Semen Strychni, Bai Longteng, Radix aconiti hemsleyani, Radix aconiti szechenyiani, Semen Sinapis Albae, Semen Impatientis, nine kinds of Chinese herbal medicine powders of Radix Clematidis respectively or together, ten groups of Mylabris, Squama Maniss are milled to fine powder, can cross 24 mesh sieves;
2, above-mentioned ten groups of sesame oils (its gram number can be chosen between 2000-3000) are poured into respectively in the pot, endure out with low baking temperature, with nine kinds of coarse powder Chinese herbal medicine mix homogeneously in above-mentioned the 1st step, pour in the pot respectively, endure the black degree that is, filter clean medicinal residues with cotton yarn, reenter clean pot, low baking temperature is endured to dripping and is not loose, the Plumbum preparatium that adds above-mentioned deal is on the same group endured to dripping into pearl from fire with slow fire, waits the medicine temperature drop to 90-100 ℃, above-mentioned ten component amounts are milled to Mylabris, the Squama Manis mixing of fine powder, pour in the pot respectively and stir evenly;
3, ten groups of difference theoretical values amount to 3600 grams, are spread out in respectively on the cloth, and outside reuse paper bag installs, and with the plastic pocket sealing, preserve stand-by;
4, get the external-applied ointment that is spread out in the pocket on the cloth and be placed on circular patch or the paster, every subsides are put 20 grams and are spread out thick 0.2-0.4 centimetre, and diameter 8-10 centimetre, be folded into semicircle the subsides, packing inspection gets final product.
The drug effect principle that product of the present invention { is stretched muscle and chased after the wind capsule } is:
Radix Clematidis: wind-damp dispelling, stopping numbness pain, current twelve channels and collaterals; Herba Siegesbeckiae: wind-damp dispelling, dredge the meridian passage heat-clearing and toxic substances removing, kind rheumatism of dispelling between bone; Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis: the wind-damp dispelling stopping numbness pain, arrogate to oneself only upper body arthralgia pain and Rhizoma Et Radix Notopterygii is warm in nature on specially, the Radix Angelicae Pubescentis warm-dryness syndrome is longer than the rheumatism numbness pain of the lower part of the body specially down, and two medicines have share synergism, Caulis Lonicerae: the meridian dredging, wind-damp dispelling, stopping numbness pain, heat-clearing and toxic substances removing.The Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Radix Ginseng: benefiting qi and nourishing blood, invigorate blood circulation YIN nourishing; The Radix Astragali: invigorating the spleen and replenishing QI, benefit is defended consolidating superficial resistance, inducing diuresis to remove edema, the function in eliminating the toxic material out by tonification; Rhizoma Gastrodiae: dispelling wind and removing obstruction in the collateral, joint joint stuffiness, numb limbs and tense tendons; Herba Taxilli: expelling wind and removing dampness, liver and kidney tonifying, bone and muscle strengthening; Herba Ephedrae: relieving the exterior syndrome by diaphoresis, diuretic disappears the second month in a season; Herba Asari: dispersing wind-cold, collateral dredging all can in wind and cold is gone into to the marrow; Olibanum, Myrrha: promoting blood circulation and stopping pain, and muscle is stretched in the relatively circulation of qi promoting of the arduous temperature of Olibanum; Myrrha: toil, the flat blood blood stasis dispelling of relatively loosing; Sanguis Draxonis: blood circulation promoting and blood stasis dispelling, hemostasis life; The Radix Polygoni Multiflori: enrich and benefit essence and blood, bone and muscle strengthening, the Yiyang of enriching blood, astringent or styptic treatment for spontaneous sweating vital essence; The Cortex Eucommiae: Rhizoma Drynariae, invigorating the liver and kidney, bone and muscle strengthening, warming and recuperating the kidney-YANG; Radix Aconiti Preparata, Radix Aconiti Kusnezoffii: expelling wind and removing dampness, dispersing cold for relieving pain; Radix Aconiti Lateralis Preparata: supporing yang firing, dispersing cold for relieving pain has stronger dispersing cold for relieving pain effect; Semen Strychni (processed): removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating is the dispelling the wind and dampness pathogens insensitive impediment, the medicine of paralysis and numbness; Agkistrodon, Zaocys, Scorpio, Scolopendra, Bombyx Batryticatus, process Catharsii molossi: its property is apt to away kind scurrying, resolving the hard mass, and removing obstruction in the collateral to relieve pain, thus all qi depressions to blood stasis, the wind card of the cold meridians of resistance, blood stasis syndrome, disease has special effect bitterly, for controlling the key medicine of insensitive impediment; Process the worm: removing blood stasis, merit are arrogated to oneself to search and are picked, and can go deep into the tunnel crack, make blood not have person with fixed attention, and gas can be declared logical, all QI and blood cohesions all open it, the property of neutralization again, removing blood stasis is not high go with, be removing blood stasis, reunion of fractured tendons and bones, the good medicine of the Jian Po wei that disappears; Formica fusca: wind-damp dispelling, physical strength profiting protects the liver, and improves body rabbit epidemic disease function; Squama Manis (processed): gas raw meat and scurrying, it is very careful that it reaches the property of scurrying, and implements meridians, reaches the pass key thoroughly, and blood circulation promoting and blood stasis dispelling is arranged, the merit of collateral dredging; Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, removing heat from blood, difference, Rhizoma Coptidis is kind to clear away heart-fire through excess-fire, kind lung heat clearing fire of Radix Scutellariae and part of the body cavity above the diaphragm housing the heart and lungs excess-fire, the kind damp-heat in lower-JIAO that rushes down clearly of Cortex Phellodendri; Radix et Rhizoma Rhei (processed with wine): blood circulation promoting and blood stasis dispelling, heat-clearing and toxic substances removing is borrowed the relieving constipation by purgation effect, wind-expelling pain-stopping; The Radix Aucklandiae, Lignum Aquilariae Resinatum: promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting are the key medicine of circulation of qi promoting; Flos Caryophylli: warming middle-JIAO to send down the adverse QI, dispersing cold for relieving pain, warming the kidney to activate YANG; Rhizoma Cyperi: dispersing the stagnated live-QI to relieve the stagnation of QI promoting the circulation of QI to relieve pain; Radix Paeoniae Rubra, Cortex Moutan: clearing away heat and cooling blood, promoting blood circulation to remove blood stasis pain relieving; Cornu Bubali: clearing away heat,cooling blood and removing toxin, Radix Saposhnikoviae is delivered diffusing wind, removing dampness to relieve pain; Radix Puerariae: expelling pathogenic factors from muscles for reducing heat, promoting the production of body fluid to quench thirst yang invigorating; Radix Scrophulariae: heat-clearing and toxic substances removing, removing heat from blood, eliminating stagnation; Radix Glycyrrhizae Preparata: invigorating the spleen and replenishing QI, drive vital organs of the human body cold and heat pathogen, be in harmonious proportion hundred medicines.
Product of the present invention (stretch muscle and chase after the wind subsides) drug effect principle is:
Semen Impatientis, Radix Clematidis: Xin Wen, slightly poisonous, its hot institute temperature is logical, and property is kind suddenly, wind-damp dispelling, the collateral dredging stopping numbness pain, the sending down the abnormal ascending QI clots absorbing, removing blood stasis, removing food stagnancy, softening hypertrophy sclerotin, " controlling " " obstructed " with " leading to " is the treatment superclass; Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Radix Anisodi Acutanguli, Semen Strychni, Radix aconiti szechenyiani, the toil temperature is very toxic, and merit is anaesthetized in careful pain, expelling wind and removing dampness, the hot temperature of loosing is logical, the function of the gas on the current whole body; Radix aconiti hemsleyani: Xin Dare, very toxic, the function invigorating blood circulation analgesia is searched the merit of wind damp eliminating; White imperial rattan: toil heat, very toxic, function is sent out liver and is induced sweat, expelling wind and removing dampness, blood circulation promoting and blood stasis dispelling, the expansion local vascular helps drug osmotic; The hot temperature of Caulis et Folium Sinapis albee powder, merit are again the energy dispersing swelling and dissipating binds at the expectorant of the meridians of dispelling, removing obstruction in the collateral to relieve pain; Mylabris, Xin Wen, very toxic, removing blood stasis counteracting toxic substances, cold effect of processing; Squama Manis: salty, be slightly cold, this product is done good works away and is worn, the energy activating blood circulation to dissipate blood stasis, the wei that disappears is long-pending, the feeling pulse function of stimulating the menstrual flow.Plumbum preparatium, suffering is slightly cold, and is poisonous, draw out pus by applying a plaster to the affected part, granulation promoting, antipruritic function is for controlling the key medicine of cream.Products characteristics of the present invention is an amount of proportioning ladies and gentlemen's poison of ingenious use, treats disease because of poison is how kind, can rise to control severe and lingering illness and more issue disease, make this ten simply medicament produce synergistic function.

Claims (3)

  1. For oral administration, the medicine for external use of 1 one kinds of wind-damp dispelling, arthralgia pain, it is characterized in that: the herbal raw material by following portions by weight is made:
    Oral medicine:
    Radix Clematidis: 5-15 Fen ， Herba Siegesbeckiae: 5-15 part, Caulis Lonicerae: 5-15 part,
    Rhizoma Et Radix Notopterygii: 2-12 part, Radix Angelicae Pubescentis: 2-12 part, the Rhizoma Atractylodis Macrocephalae: 2-12 part,
    Radix Angelicae Sinensis: 1-10 part, Radix Rehmanniae Preparata: 1-10 part, Radix Ginseng: 1-10 part,
    The Radix Astragali: 5-15 part, Rhizoma Gastrodiae: 1-12 part, Herba Taxilli: 2-12 part,
    Herba Ephedrae: 1-10 part, Herba Asari: 0.4-4 part, Olibanum: 2-12 part,
    Myrrha: 2-12 part, the Cortex Eucommiae: 2-12 part, Rhizoma Drynariae: 0.4-4 part,
    Radix Aconiti Preparata: 1-10 part, Radix Aconiti Kusnezoffii Preparata: 1-10 part, Radix Aconiti Lateralis Preparata: 0.4-4 part,
    Semen Strychni (processed): 0.4-4 part, Agkistrodon: 2-12 part, Zaocys: 2-12 part,
    Pheretima: 2-12 part, Scolopendra: 1-10 part, Scorpio: 1-10 part,
    Process Catharsii molossi: 1-10 part, process the worm: 1-10 part, Formica fusca: 5-15 part,
    Squama Manis (processed): 0.4-4 part, Bombyx Batryticatus: 1-10 part, Rhizoma Coptidis: 0.6-6 part,
    Cortex Phellodendri: 0.6-6 part, Radix Scutellariae: 0.6-6 part, Radix et Rhizoma Rhei (processed with wine): 0.6-6 part,
    Rhizoma Anemones Raddeanae: 0.5-5 part, Rhizoma Chuanxiong: 2-12 part, the Radix Aucklandiae: 0.4-4 part,,
    Lignum Aquilariae Resinatum: 0.4-4 part, Flos Caryophylli: 0.4-4 part, Rhizoma Cyperi: 0.4-4 part,
    Radix Puerariae: 2-12 part, Cornu Bubali: 2-12 part, Cortex Moutan: 1-10 part,
    Radix Glycyrrhizae Preparata: 2-12 part, Radix Scrophulariae: 0.4-4 part;
    Medicine for external use:
    Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani): 5-20 part, Radix Anisodi Acutanguli: 5-15 part; Semen Strychni: 3-12 part,
    White imperial rattan: 3-12 part, Radix aconiti hemsleyani: 5-15 part, Radix aconiti szechenyiani: 3-12 part,
    Semen Sinapis Albae: 10-30 part, Mylabris: 0.1-0.4 part, Squama Manis: 3-12 part,
    Radix Clematidis: 10-20 part, Semen Impatientis: 10-20 part, Plumbum preparatium: 1000-1250 part,
    Sesame oil: 2000-3000 part.
  2. 2, make the manufacturing technique method of for oral administration, the medicine for external use of the described a kind of wind-damp dispelling of claim 1, stopping numbness pain, it is characterized in that:
    The manufacture method of oral medicine in turn includes the following steps:
    Get the Chinese herbal medicine above-mentioned for oral administration of clean dry, be milled to fine powder respectively or after mixing by above-mentioned deal proportioning, can cross 240 mesh sieves, behind the uniform mixing, ultraviolet and/or 〉=sterilize under 100 ℃ of high temperature, per 0.75 gram fine powder Chinese herbal medicine of weighing is loaded on " 0 " number capsule, whenever bottledly goes into 100 capsules and gets final product through checking;
    The manufacture method of medicine for external use in turn includes the following steps:
    1. get the above-mentioned Chinese herbal medicine for external use of clean dry, respectively or together Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani), Radix Anisodi Acutanguli, Semen Strychni, Bai Longteng, Radix aconiti hemsleyani, Radix aconiti szechenyiani, Semen Sinapis Albae, Semen Impatientis, nine kinds of Chinese herbal medicine powders of Radix Clematidis are broken into coarse powder by above-mentioned deal proportioning, Mylabris, Squama Manis are milled to fine powder, can cross 240 mesh sieves;
    2. sesame oil is poured in the pot, endured out, nine kinds of coarse powder Chinese herbal medicine mix homogeneously in above-mentioned the 1st step with low baking temperature, pour in the pot, enduring black is degree, filters clean medicinal residues with cotton yarn, reenters clean pot, low baking temperature is endured to dripping and is not loose, the Plumbum preparatium that adds above-mentioned deal is endured to dripping into pearl from fire with slow fire, waits the medicine temperature drop to 90-100 ℃, above-mentioned deal is milled to Mylabris, the Squama Manis mixing of fine powder, pours in the pot and stir evenly;
    3. be spread out on the cloth, outside reuse paper bag installs, and with the plastic pocket sealing, preserves stand-by;
    4. get the external-applied ointment that is spread out in the pocket on the cloth and be placed on circular patch or the paster, 20 grams are put in every subsides, spread out thick 0.2-0.4 centimetre, and diameter 8-10 centimetre, be folded into semicircle the subsides, packing inspection gets final product.
  3. 3, for oral administration, the medicine for external use of wind-damp dispelling according to claim 1, stopping numbness pain, it is characterized in that: the parts by weight of raw material following Chinese medicinal herb raw wherein also can be made up of following proportioning:
    Oral medicine:
    Herba Asari: 0.4-2 part, Radix Aconiti Preparata: 1-8 part, Radix Aconiti Kusnezoffii Preparata: 1-8 part,
    Semen Strychni (processed): 1-6 part, Agkistrodon: 2-8 part, Zaocys: 2-8 part,
    Pheretima: 2-8 part, Scolopendra: 1-8 part, Scorpio: 1-8 part,
    Process Catharsii molossi: 1-8 part, process the worm: 1-8 part, Bombyx Batryticatus: 1-4 part,
    Rhizoma Anemones Raddeanae: 0.5-6 part;
    Medicine for external use:
    Radix Aconiti Brachypodi (Radix Aconiti Szechenyiani): 5-10 part, Radix Anisodi Acutanguli: 5-10 part, Bai Longteng: 3-6 part,
    Radix aconiti hemsleyani: 5-10 part, Squama Manis: 3-6 part, Radix Clematidis: 5-10 part,
    Semen Impatientis: 5-10 part, Mylabris: 0.1-0.2 part.
CNB021019681A 2002-01-19 2002-01-19 Oral taken and external use medicine for antirheumatism and stopping numbness pain Expired - Fee Related CN1211103C (en)

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