CN105547922A - Microviscosimeter based on micro/nano channel - Google Patents
Microviscosimeter based on micro/nano channel Download PDFInfo
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- CN105547922A CN105547922A CN201510921213.2A CN201510921213A CN105547922A CN 105547922 A CN105547922 A CN 105547922A CN 201510921213 A CN201510921213 A CN 201510921213A CN 105547922 A CN105547922 A CN 105547922A
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
- G01N11/02—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material
- G01N11/04—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture
- G01N11/06—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by timing the outflow of a known quantity
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Abstract
A microviscosimeter based on a micro/nano channel includes a power supply; the power supply is connected with a temperature control system and a sample introduction system, the sample introduction system is located inside the temperature control system, and the temperature control system controls the temperature of the sample introduction system and the temperature of a liquid in the sample introduction system; the sample introduction system is connected with an inlet of a channel with the depth of micro/nano scale, and an outlet of the micro/nano-scale channel directly communicates with the atmosphere; the micro/nano-scale channel is located inside a data measuring and processing module, the output of the data measuring and processing module is connected with the input of a display module, the data measuring and processing module is used for data measurement and calculation of liquid viscosity, and a viscosity calculation result is displayed by the data display module; control ends of the temperature control system, the sample introduction system and the data measuring and processing module are connected with a control module. The microviscosimeter has the advantages of precious little required liquid amount, simple device, simple operation, convenience for carrying, and rapid measurement.
Description
Technical field
The present invention relates to a kind of microviscosimeter, be specifically related to a kind of microviscosimeter based on micrometer/nanometer passage.
Background technology
Viscosity is one of important physical characteristics of fluid, and existing Viscosity Measurement Methods mainly contains capillary tube technique, Constructional Elements Using Falling Methods, rotary process, vibratory drilling method, flat band method etc.Because capillary tube technique is simple and practical, therefore the range of application of the current measurement mechanism based on capillary tube technique design is wider.Kapillary ratio juris is Ha Gen-Poiseuille's formula, flows through kapillary by external pressure drive fluid, measures the pressure reduction at kapillary two ends and the flow of fluid, and is revised, just can calculate the viscosity of fluid.The subject matter that the device measuring viscosity based on capillary tube technique at present exists has: the accurate measurement of pressure reduction, flow is comparatively difficult, measuring required experimental liquid in addition, more (in measurement mechanism, capillary inner diameter is generally mm magnitude, required experimental liquid is at tens milliliters), but the experimental liquid that sometimes can provide very limited (blood or some physiological fluid sample are generally tens microlitres).These bring challenge all to the development of capillary tube technique measuring technique, therefore, solve in the urgent need to development new technology, new approaches the difficult problem run in capillary tube technique measuring process.
Summary of the invention
In order to overcome the shortcoming of above-mentioned prior art, the object of the present invention is to provide a kind of microviscosimeter based on micrometer/nanometer passage, having required amount of liquid few, device is simple, simple to operate, be easy to carry, and measures feature rapidly.
For achieving the above object, the technical scheme that the present invention takes is:
Based on a microviscosimeter for micrometer/nanometer passage, comprise power supply 1, power supply 1 is connected with temperature control system 2 and sampling system 3 respectively, and it is inner that sampling system 3 is in temperature control system 2, is controlled the temperature of sampling system 3 and wherein liquid by temperature control system 2; Sampling system 3 and the degree of depth are that the entrance of micrometer/nanometer magnitude passage 4 is connected, and air is led directly in the outlet of micrometer/nanometer magnitude passage 4; Micrometer/nanometer magnitude passage 4 is positioned at DATA REASONING and processing module 5 is inner, the output of DATA REASONING and processing module 5 is connected with the input of display module 6, DATA REASONING and processing module 5 are for DATA REASONING and calculate liquid viscosity, show viscosity calculations result by data disaply moudle 6; Temperature control system 2, sampling system 3 are connected with control module 7 with the control end of DATA REASONING and processing module 5.
The data processing module 16 that described DATA REASONING and processing module 5 comprise data measurement module 8 and be attached thereto, data measurement module 8 includes photoelectric subassembly more than two arranged side by side successively, two adjacent groups photoelectric subassembly is at a distance of 1 μm-100 μm, often organize photoelectric subassembly and comprise an optical transmitting set and a light absorber, optical transmitting set and light absorber are placed on micrometer/nanometer passage 4 both sides respectively, the output of optical transmitting set, light absorber is connected with the input of timing circuit 9, and the output of timing circuit 9 is connected with the input of data processing module 16.
Described micrometer/nanometer magnitude passage 4 is single use.
Described DATA REASONING and processing module 5 can complete in 10 seconds to be measured and process, without the need to applying pressure differential, according to LW model, according to flow distance and the relation of time, calculates the viscosity of liquid.
Beneficial effect of the present invention is: be that the passage of micrometer/nanometer magnitude is as kapillary to reduce the use of experimental liquid using the degree of depth, flowed by capillary pressure drive fluid, save differential pressure measurement system, the LW model met when flowing in kapillary based on liquid, by being placed in the other timing circuit system of capillary pipeline, measure liquid not flow distance in the same time in kapillary, calculate the viscosity number of liquid in conjunction with LW model, have the following advantages;
Degree of depth amount of liquid needed for micrometer/nanometer magnitude passage 4 is few, can be less than 1 μ l; Micrometer/nanometer magnitude passage 4 is single use, avoids infection, does not need cleaning device, and passageway machining technology maturation; Device is simple, fluid capillary pressure drive dirty enter micron/nanometer scale passage 4, do not need external pressurized device, do not need pressure measurement unit; Simple to operate, be easy to carry.Measure rapidly, measurement and data processing can complete in 10 seconds, and the biological samples such as blood need not add anti-freezing reagent.
Accompanying drawing explanation
Fig. 1 is the structural representation of the embodiment of the present invention.
Fig. 2 is the structural representation of DATA REASONING and processing module 5 in Fig. 1.
Embodiment
Below in conjunction with drawings and Examples, the present invention is described in detail.
With reference to Fig. 1, a kind of microviscosimeter based on micrometer/nanometer passage, comprises power supply 1, and power supply 1 is connected with temperature control system 2 and sampling system 3 respectively, and it is inner that sampling system 3 is in temperature control system 2, is controlled the temperature of sampling system 3 and wherein liquid by temperature control system 2; Sampling system 3 and the degree of depth are that the entrance of micrometer/nanometer magnitude passage 4 is connected, and air is led directly in the outlet of micrometer/nanometer magnitude passage 4; Micrometer/nanometer magnitude passage 4 is positioned at DATA REASONING and processing module 5 is inner, the output of DATA REASONING and processing module 5 is connected with the input of display module 6, DATA REASONING and processing module 5 are for DATA REASONING and calculate liquid viscosity, show viscosity calculations result by data disaply moudle 6; Temperature control system 2, sampling system 3 are connected with control module 7 with the control end of DATA REASONING and processing module 5.
With reference to Fig. 2, the data processing module 16 that described DATA REASONING and processing module 5 comprise data measurement module 8 and be attached thereto, data measurement module 8 comprises the first photoelectric subassembly 10 arranged side by side successively, second photoelectric subassembly 11, 3rd photoelectric subassembly 12, 4th photoelectric subassembly 13, 5th photoelectric subassembly 14, 6th photoelectric subassembly 15, two adjacent groups photoelectric subassembly is at a distance of 1 μm-100 μm, often organize photoelectric subassembly and comprise an optical transmitting set and a light absorber, optical transmitting set and light absorber are placed on micrometer/nanometer magnitude passage 4 both sides respectively, be used for measuring not liquid flow distance in the same time, optical transmitting set, the output of light absorber is connected with the input of timing circuit 9, the output of timing circuit 9 is connected with the input of data processing module 16.In measuring process, liquid crosses micrometer/nanometer magnitude passage 4 at capillary force flows by action, when first group of photoelectric subassembly 10 detects that liquid end face in micrometer/nanometer magnitude passage 4 is through out-of-date, the time recorded by timing circuit 9, in like manner, second photoelectric subassembly 11, the 3rd photoelectric subassembly 12, the 4th photoelectric subassembly 13, the 5th photoelectric subassembly 14, the 6th photoelectric subassembly 15 record the time at liquid end face through out-of-date respectively, data are finally transferred in data processing module 16, and data processing module 16 calculates the viscosity of liquid.
Described micrometer/nanometer magnitude passage 4 is single use.
Described DATA REASONING and processing module 5 can complete in 10 seconds to be measured and process, without the need to applying pressure differential, according to LW model, according to flow distance and the relation of time, calculates the viscosity of liquid.
Principle of work of the present invention is:
Micro-injection pump in sampling system 3 is taken off, draws testing liquid sample, afterwards micro-injection pump is put into sampling system 3; Opening power 1 and control module 7, opening temp. control module 2, treat its steady operation, testing liquid is delivered to micrometer/nanometer magnitude passage 4 porch by sampling system 3, liquid enters micron/nanometer scale passage 4 at capillary force flows by action, DATA REASONING and processing module 5 to not in the same time the distance of liquid measure, process is as follows: liquid end face is when photoelectric subassembly 10, and this moment t recorded by timing circuit 9
1, in like manner, the moment t of photoelectric subassembly 11,12,13,14,15 when recording liquid end face flows through respectively
2, t
3, t
4, t
5, t
6, obtain the data of 6 groups of flow distance l and time t, all data are all transferred in data processing module 16, according to LW model (when the height of passage is much smaller than width, i.e. h<<w)
In formula, l (t) is the flow distance of t liquid, and h is channel depth, and θ is the contact angle between liquid and channel wall, σ
lVwith surface tension and kinetic viscosity that η is liquid respectively.Suppose the viscosities il of liquid in above formula, contact angle θ
econstant in flow process, so length of flow l (t) and t
1/2be directly proportional, channel depth h, surface tension coefficient σ
lVand contact angle θ
eeasily measure and obtain, as long as therefore measure one group of l ~ t just can go out the viscosities il of liquid by inverse,
This value is transferred to data disaply moudle 6 and shows, and flow process continues 1-2s, and therefore this measurement and processing procedure can complete in 10s.For non-Newtonian fluid, this method can according to the relation revising LW model or CFD calculating acquisition fluid viscosity and shearing rate.
Claims (4)
1. the microviscosimeter based on micrometer/nanometer passage, comprise power supply (1), power supply (1) is connected with temperature control system (2) and sampling system (3) respectively, it is characterized in that: it is inner that sampling system (3) is in temperature control system (2), controlled the temperature of sampling system (3) and wherein liquid by temperature control system (2); Sampling system (3) and the degree of depth are that the entrance of micrometer/nanometer magnitude passage (4) is connected, and air is led directly in the outlet of micrometer/nanometer magnitude passage (4); Micrometer/nanometer magnitude passage (4) is positioned at DATA REASONING and processing module (5) is inner, the output of DATA REASONING and processing module (5) is connected with the input of display module (6), DATA REASONING and processing module (5) are for DATA REASONING and calculate liquid viscosity, show viscosity calculations result by data disaply moudle (6); Temperature control system (2), sampling system (3) are connected with control module (7) with the control end of DATA REASONING and processing module (5).
2. a kind of microviscosimeter based on micrometer/nanometer passage according to claim 1, it is characterized in that: the data processing module (16) that described DATA REASONING and processing module (5) comprise data measurement module (8) and be attached thereto, data measurement module (8) includes photoelectric subassembly more than two arranged side by side successively, two adjacent groups photoelectric subassembly is at a distance of 1 μm-100 μm, often organize photoelectric subassembly and comprise an optical transmitting set and a light absorber, optical transmitting set and light absorber are placed on micrometer/nanometer passage (4) both sides respectively, optical transmitting set, the output of light absorber is connected with the input of timing circuit (9), the output of timing circuit (9) is connected with the input of data processing module (16).
3. a kind of microviscosimeter based on micrometer/nanometer passage according to claim 1, is characterized in that: described micrometer/nanometer magnitude passage (4) is single use.
4. a kind of microviscosimeter based on micrometer/nanometer passage according to claim 1, it is characterized in that: described DATA REASONING and processing module (5) can complete in 10 seconds to be measured and process, without the need to applying pressure differential, according to LW model, according to flow distance and the relation of time, calculate the viscosity of liquid.
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| CN201510921213.2A CN105547922A (en) | 2015-12-11 | 2015-12-11 | Microviscosimeter based on micro/nano channel |
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| CN201510921213.2A CN105547922A (en) | 2015-12-11 | 2015-12-11 | Microviscosimeter based on micro/nano channel |
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| CN201510921213.2A Pending CN105547922A (en) | 2015-12-11 | 2015-12-11 | Microviscosimeter based on micro/nano channel |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107314952A (en) * | 2017-07-12 | 2017-11-03 | 清华大学 | A kind of method and system for measuring dynamic contact angle under extremely low capillary number |
| CN107346360A (en) * | 2017-07-12 | 2017-11-14 | 清华大学 | A kind of determination method and system for receiving fluid parameter in flow control system |
| CN107389502A (en) * | 2017-07-12 | 2017-11-24 | 清华大学 | A kind of method and system for measuring liquid viscosity |
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| US20060179923A1 (en) * | 2004-09-24 | 2006-08-17 | Burns Mark A | Nanoliter viscometer for analyzing blood plasma and other liquid samples |
| CN102768169A (en) * | 2011-05-05 | 2012-11-07 | 中国科学院大连化学物理研究所 | Method for measuring viscosity of Newtonian fluid by utilization of pressure drop of micro-channel |
| CN102944500A (en) * | 2012-11-07 | 2013-02-27 | 重庆大学 | Passageway device and system for detecting viscosity of liquid as well as application thereof |
| WO2014128478A2 (en) * | 2013-02-21 | 2014-08-28 | Malvern Instruments Limited | Imaging microviscometer |
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2015
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Patent Citations (4)
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| US20060179923A1 (en) * | 2004-09-24 | 2006-08-17 | Burns Mark A | Nanoliter viscometer for analyzing blood plasma and other liquid samples |
| CN102768169A (en) * | 2011-05-05 | 2012-11-07 | 中国科学院大连化学物理研究所 | Method for measuring viscosity of Newtonian fluid by utilization of pressure drop of micro-channel |
| CN102944500A (en) * | 2012-11-07 | 2013-02-27 | 重庆大学 | Passageway device and system for detecting viscosity of liquid as well as application thereof |
| WO2014128478A2 (en) * | 2013-02-21 | 2014-08-28 | Malvern Instruments Limited | Imaging microviscometer |
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Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107314952A (en) * | 2017-07-12 | 2017-11-03 | 清华大学 | A kind of method and system for measuring dynamic contact angle under extremely low capillary number |
| CN107346360A (en) * | 2017-07-12 | 2017-11-14 | 清华大学 | A kind of determination method and system for receiving fluid parameter in flow control system |
| CN107389502A (en) * | 2017-07-12 | 2017-11-24 | 清华大学 | A kind of method and system for measuring liquid viscosity |
| CN107314952B (en) * | 2017-07-12 | 2019-06-18 | 清华大学 | A kind of method and system measuring dynamic contact angle under extremely low capillary number |
| CN107389502B (en) * | 2017-07-12 | 2019-07-26 | 清华大学 | A kind of method and system measuring liquid viscosity |
| CN107346360B (en) * | 2017-07-12 | 2020-04-28 | 清华大学 | Method and system for determining fluid parameters in nanofluidic system |
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