CN105535702A - Traditional Chinese medicine composition for preventing and treating newcastle disease and preparation method thereof - Google Patents

Traditional Chinese medicine composition for preventing and treating newcastle disease and preparation method thereof Download PDF

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CN105535702A
CN105535702A CN201610034115.1A CN201610034115A CN105535702A CN 105535702 A CN105535702 A CN 105535702A CN 201610034115 A CN201610034115 A CN 201610034115A CN 105535702 A CN105535702 A CN 105535702A
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chinese medicine
medicine composition
newcastle disease
rhizoma
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肖华
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
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    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
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Abstract

The invention relates to a traditional Chinese medicine composition for preventing and treating a newcastle disease. The traditional Chinese medicine composition for preventing and treating the newcastle disease is prepared from the following raw materials in parts by weight: 250-300 parts of astragalus, 100-150 parts of coptidis rhizome, 50-80 parts of atractylodes macrocephala koidz, 50-60 parts of peony tree bark, 150-200 parts of heartleaf houttuynia herb, 40-50 parts of common bletilla pseudobulb, 40-50 parts of sanguisorba officinalis, 70-100 parts of chrysanthemum, 150-200 parts of malt, 10-20 parts of croton, 20-30 parts of indigo naturalis, 10-20 parts of centipeda minima, 50-70 parts of radix bupleuri, 50-70 parts of cuttlebone, 20-30 parts of poria cocos, 30-50 parts of purple perilla, 150-170 parts of bee pollen and 1000-1500 parts of rice bran powder. The traditional Chinese medicine composition for preventing and treating the newcastle disease selects multiple natural Chinese herbal medicines as raw material, which meets requirements of the modern cultivation industry on green and natural cultivation; the traditional Chinese medicine composition can replace the traditional western medicine so as to prevent antibiotics or hormone type medicines and chemical synthesis type medicines from remaining in animal bodies, which is more beneficial to the health of medicine eaters.

Description

A kind of Chinese medicine composition preventing and treating newcastle disease and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicine composition preventing and treating newcastle disease, it can use as a part for feedstuff, also can be used as the treatment of newcastle disease disease as medicine.
Background technology
Newcastle (newcastledisease, ND) be cause that the one of fowl is acute, hot by paramyxovirus-Avian pneumo-encephalitis virus, septic and high degree in contact sexually transmitted disease.Hemorrhage for feature with high heat, dyspnea, dysentery, neurological disorders, mucosa and serous coat.Have very high sickness rate and case fatality rate, be a kind of Infectious Diseases of harm aviculture, OIE is classified as category-A epidemic disease, also known as philippine fowl disease or pseudo-fowl plague.This disease often in acute sepsis shape, principal character be dyspnea, just rare, neurological disorders, mucosa and serous coat are hemorrhage, mortality rate is high, serious to poultry husbandry harm.First nineteen twenty-six is found in Indonesia, and find at Britain's new city again soon, all there is popular record countries in the world, have virulent strain and low virulent strain two class.Chicken section animal all can suffer from suffers from primary disease, and the most susceptible of family chicken, chickling is higher than Adult Chicken susceptibility.Ill chicken body temperature can reach 44 DEG C, down in spirits, feather pine disorderly, in lethargy shape, hat and wattle kermesinus or black purple, crop is spoken in a low voice and is interiorly often full of liquid and gas, dyspnea, and throat sends cackle; Feces is thin, stench, and general 2 ~ 5 days dead; Subacute or chronic type symptom is similar to acute, only the state of an illness is comparatively light, occurs nervous symptoms, and lower limb, wing are benumbed, movement disorder, and head is to layback or to bending etc., the course of disease can reach 1 ~ 2 month, most final death.
Still lack effective medicine for newcastle at present to prevent and treat, the diffusion for epidemic situation also lacks effective control device.Existing treatment means mainly contains, and " golden GANKANG is safe "+" compound Radix Astragali polysaccharide granule " drink water 3-5 days, and then " potent amoxicillin " spice 3-5 days, prevents secondary infection; Or clear pestilence gram poison or golden GANKANG Thailand drinking-water are used in conjunction 3-5 days, ice toad falls apart or antipyretic and antitoxic powder spice is used in conjunction 3-5 days, the vertical strong or Enterobacter cloaca good fortune drinking-water of intestinal is used in conjunction 3-5 days and controls secondary infection, when respiratory tract is serious, coordinate " exhaling GANKANG " or " exhaling Thailand " drinking-water to be used in conjunction 3-5 days, coordinate " nutrition cable release " to alleviate stress simultaneously.But above treatment means is not good especially for the therapeutic effect of this disease, after general newcastle outburst, the survival rate after chickling treatment is 60-70%, and the survival rate of chick is 75-85%, and this is also great economic loss for culturist.Except above treatment means, prophylactic immunization and strict disinfection and isolation, cut off route of transmission, big-and-middle-sized chicken house should perform " all-in and all-out " system, not open to visitors, strengthen quarantine, prevent animal from entering susceptible chicken group, staff, vehicles while passing also must be control the popular Main Means of this disease at present through strict sterilization process.But above control device can not be cured newcastle completely or be avoided the diffusion of disease.
Summary of the invention
For the medicine of effectively not treating newcastle in prior art, also the means effectively controlling newcastle diffusion are lacked, the present invention aims to provide a kind of Chinese medicine composition preventing and treating newcastle disease, it both can as feed additive, long-term feeding to chicken reaches prophylactic effect, also as medicine, the diffusion of newcastle disease and this sick epidemic situation of control can be used for the treatment of.
For solving above technical problem, the present invention adopts following technological means:
A kind of Chinese medicine composition preventing and treating newcastle disease, it is characterized in that, be made up of the raw material of following weight portion: Radix Astragali 250-300 part, Rhizoma Coptidis 100-150 part, Rhizoma Atractylodis Macrocephalae 50-80 part, Cortex Moutan 50-60 part, Herba Houttuyniae 150-200 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-50 part, Radix Sanguisorbae 40-50 part, Flos Chrysanthemi 70-100 part, Fructus Hordei Germinatus 150-200 part, Fructus Crotonis 10-20 part, Indigo Naturalis 20-30 part, Herba Centipedae 10-20 part, Radix Bupleuri 50-70 part, extra large Piao sheath 50-70 part, Poria 20-30 part, Folium Perillae 30-50 part, bee pollen 150-170 part, bran powder 1000-1500 part.
Preferably, be made up of the raw material of following weight portion: the Radix Astragali 250 parts, Rhizoma Coptidis 100 parts, the Rhizoma Atractylodis Macrocephalae 50 parts, Cortex Moutan 50 parts, Herba Houttuyniae 150 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 40 parts, Radix Sanguisorbae 40 parts, Flos Chrysanthemi 70 parts, 150 parts, Fructus Hordei Germinatus, Fructus Crotonis 10 parts, Indigo Naturalis 20 parts, Herba Centipedae 10 parts, Radix Bupleuri 50 parts, 50 parts, extra large Piao sheath, 20 parts, Poria, Folium Perillae 30 parts, bee pollen 150 parts, bran powder 1000 parts.
Preferably, be made up of the raw material of following weight portion: the Radix Astragali 300 parts, Rhizoma Coptidis 150 parts, the Rhizoma Atractylodis Macrocephalae 80 parts, Cortex Moutan 60 parts, Herba Houttuyniae 200 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 50 parts, Radix Sanguisorbae 50 parts, Flos Chrysanthemi 100 parts, 200 parts, Fructus Hordei Germinatus, Fructus Crotonis 20 parts, Indigo Naturalis 30 parts, Herba Centipedae 20 parts, Radix Bupleuri 70 parts, 70 parts, extra large Piao sheath, 30 parts, Poria, Folium Perillae 50 parts, bee pollen 170 parts, bran powder 1500 parts.
Preferably, be made up of the raw material of following weight portion: the Radix Astragali 280 parts, Rhizoma Coptidis 120 parts, the Rhizoma Atractylodis Macrocephalae 60 parts, Cortex Moutan 55 parts, Herba Houttuyniae 180 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 45 parts, Radix Sanguisorbae 45 parts, Flos Chrysanthemi 80 parts, 180 parts, Fructus Hordei Germinatus, Fructus Crotonis 15 parts, Indigo Naturalis 25 parts, Herba Centipedae 15 parts, Radix Bupleuri 60 parts, 60 parts, extra large Piao sheath, 25 parts, Poria, Folium Perillae 40 parts, bee pollen 160 parts, bran powder 1300 parts.
The Chinese medicine composition preventing and treating newcastle disease of the present invention is prepared from by following methods:
Step one, takes each raw material by weight;
Step 2, after the Radix Astragali taken, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Chrysanthemi, Fructus Crotonis, Indigo Naturalis, Herba Centipedae, Radix Bupleuri, Poria and Folium Perillae are mixed, add the water of this mixture quality 3 times, extract 12-18 hour at the temperature of about 80-90 DEG C after, filter and obtain water extraction filtrate;
Step 3, after the Cortex Moutan taken, Herba Houttuyniae, Radix Sanguisorbae being mixed, the volumetric concentration adding this mixture quality 1 times is the ethanol water of 50%, be placed in hermetic container, extract 18-24 hour under the condition of about 50-60 DEG C after, pulverized and made serosity, be alcohol extraction serosity;
Step 4, pulverizes rear mistake 60 mesh sieve respectively by the Fructus Hordei Germinatus taken, extra large Piao sheath and bee pollen, then mixes with bran powder, then mix with the water extraction filtrate of step 2, the alcohol extraction serosity of step 3, carry out cold drying after stirring, and obtains dry compound;
Step 5, pulverizes the mixed material of drying, is ground into 50-60 object powder, namely obtains the Chinese medicine composition preventing and treating newcastle disease of the present invention.
Using method of preventing and treating the Chinese medicine composition of newcastle disease of the present invention is: it can add use according to the mass percentage of 0.5-0.8% in chicken feedstuff, plays the effect of prevention newcastle disease; Also can add according to the mass percentage of 2-5% in chicken feedstuff and use, play the effect for the treatment of newcastle disease, also can feed separately the Chinese medicine composition preventing and treating newcastle disease of the present invention to play therapeutical effect, the consumption of feeding of recommendation is 2-4g Chinese medicine composition/kg body weight/day.
Based on above technical scheme, tool of the present invention has the following advantages and beneficial effect:
First, the pathogeny and the disease that the present invention is based on newcastle characterize, according to the therapy theory of Chinese medicine, multiple natural drug has been selected to combine, wherein selected efficacy of drugs is as follows: Radix Astragali invigorating QI to consolidate the body surface resistance, Rhizoma Coptidis heat clearing and damp drying, Rhizoma Atractylodis Macrocephalae the spleen strengthening and damp drying, Cortex Moutan yin nourishing removing heat from blood, Herba Houttuyniae heat-clearing and toxic substances removing, inducing diuresis to remove edema, Pseudobulbus Bletillae (Rhizoma Bletillae), Radix Sanguisorbae hemostasis antidiarrheal, Fructus Hordei Germinatus, Flos Chrysanthemi liver heat removing spleen invigorating, Fructus Crotonis rushes down long-pending sensible, by expectorant parasite killing, Indigo Naturalis heat-clearing and toxic substances removing, removing heat from blood, Herba Centipedae (eritrichium pedumculare) expelling wind and cold, Radix Bupleuri reconciling superficies and interior, soothing the liver yang invigorating, sea Piao sheath astringing to arrest bleeding, relieving gastric hyperacidity to alleviate stomachache, Poria mind tranquilizing and the heart calming, strengthening the spleen stomach function regulating, eliminating dampness and diuresis, Folium Perillae dispersing wind-cold, circulation of qi promoting is amusing.Based on the combination of above medicine, the wherein Radix Astragali, Rhizoma Coptidis, Herba Houttuyniae, bee pollen and Fructus Hordei Germinatus are monarch drug, chief complaint for newcastle characterizes, the Rhizoma Atractylodis Macrocephalae, Cortex Moutan, Flos Chrysanthemi, Radix Sanguisorbae, Pseudobulbus Bletillae (Rhizoma Bletillae) is ministerial drug, Radix Bupleuri, sea Piao sheath, Poria and Folium Perillae are auxiliary, Fructus Crotonis, Indigo Naturalis is as guiding drug, mutually working in coordination with between above medicine, accurate cooperation, achieve the technique effect of 1+1>2, to newcastle, there is effective epidemic prevention and therapeutical effect, through realizing showing, Chinese medicine composition of the present invention can reduce the mortality rate in newcastle outburst, overall raising fanning economics more than 10%.
Secondly, the present invention selects multiple natural Chinese medicinal herb to be raw material, it meets modern farming for green, natural pursuit, and it can substitute traditional western medicine therapy, avoid antibiotic or hormone medicine, chemosynthesis class medicine in animal body residual, be more of value to the health of user.
detailed description of the invention:
embodiment 1: a kind of Chinese medicine composition preventing and treating newcastle disease, be made up of the raw material of following weight portion: the Radix Astragali 250 parts, Rhizoma Coptidis 100 parts, the Rhizoma Atractylodis Macrocephalae 50 parts, Cortex Moutan 50 parts, Herba Houttuyniae 150 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 40 parts, Radix Sanguisorbae 40 parts, Flos Chrysanthemi 70 parts, 150 parts, Fructus Hordei Germinatus, Fructus Crotonis 10 parts, Indigo Naturalis 20 parts, Herba Centipedae 10 parts, Radix Bupleuri 50 parts, 50 parts, extra large Piao sheath, 20 parts, Poria, Folium Perillae 30 parts, bee pollen 150 parts, bran powder 1000 parts.
The described Chinese medicine composition preventing and treating newcastle disease is prepared from by following methods:
Step one, takes each raw material by weight;
Step 2, after the Radix Astragali taken, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Chrysanthemi, Fructus Crotonis, Indigo Naturalis, Herba Centipedae, Radix Bupleuri, Poria and Folium Perillae are mixed, add the water of this mixture quality 3 times, extract 12-18 hour at the temperature of about 80-90 DEG C after, filter and obtain water extraction filtrate;
Step 3, after the Cortex Moutan taken, Herba Houttuyniae, Radix Sanguisorbae being mixed, the volumetric concentration adding this mixture quality 1 times is the ethanol water of 50%, be placed in hermetic container, extract 18-24 hour under the condition of about 50-60 DEG C after, pulverized and made serosity, be alcohol extraction serosity;
Step 4, pulverizes rear mistake 60 mesh sieve respectively by the Fructus Hordei Germinatus taken, extra large Piao sheath and bee pollen, then mixes with bran powder, then mix with the water extraction filtrate of step 2, the alcohol extraction serosity of step 3, carry out cold drying after stirring, and obtains dry compound;
Step 5, pulverizes the mixed material of drying, is ground into 50-60 object powder, namely obtains the Chinese medicine composition preventing and treating newcastle disease of the present invention.
embodiment 2: a kind of Chinese medicine composition preventing and treating newcastle disease, be made up of the raw material of following weight portion: the Radix Astragali 300 parts, Rhizoma Coptidis 150 parts, the Rhizoma Atractylodis Macrocephalae 80 parts, Cortex Moutan 60 parts, Herba Houttuyniae 200 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 50 parts, Radix Sanguisorbae 50 parts, Flos Chrysanthemi 100 parts, 200 parts, Fructus Hordei Germinatus, Fructus Crotonis 20 parts, Indigo Naturalis 30 parts, Herba Centipedae 20 parts, Radix Bupleuri 70 parts, 70 parts, extra large Piao sheath, 30 parts, Poria, Folium Perillae 50 parts, bee pollen 170 parts, bran powder 1500 parts.
The described Chinese medicine composition preventing and treating newcastle disease is prepared from by following methods:
Step one, takes each raw material by weight;
Step 2, after the Radix Astragali taken, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Chrysanthemi, Fructus Crotonis, Indigo Naturalis, Herba Centipedae, Radix Bupleuri, Poria and Folium Perillae are mixed, add the water of this mixture quality 3 times, extract 12-18 hour at the temperature of about 80-90 DEG C after, filter and obtain water extraction filtrate;
Step 3, after the Cortex Moutan taken, Herba Houttuyniae, Radix Sanguisorbae being mixed, the volumetric concentration adding this mixture quality 1 times is the ethanol water of 50%, be placed in hermetic container, extract 18-24 hour under the condition of about 50-60 DEG C after, pulverized and made serosity, be alcohol extraction serosity;
Step 4, pulverizes rear mistake 60 mesh sieve respectively by the Fructus Hordei Germinatus taken, extra large Piao sheath and bee pollen, then mixes with bran powder, then mix with the water extraction filtrate of step 2, the alcohol extraction serosity of step 3, carry out cold drying after stirring, and obtains dry compound;
Step 5, pulverizes the mixed material of drying, is ground into 50-60 object powder, namely obtains the Chinese medicine composition preventing and treating newcastle disease of the present invention.
embodiment 3: a kind of Chinese medicine composition preventing and treating newcastle disease, be made up of the raw material of following weight portion: the Radix Astragali 280 parts, Rhizoma Coptidis 120 parts, the Rhizoma Atractylodis Macrocephalae 60 parts, Cortex Moutan 55 parts, Herba Houttuyniae 180 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 45 parts, Radix Sanguisorbae 45 parts, Flos Chrysanthemi 80 parts, 180 parts, Fructus Hordei Germinatus, Fructus Crotonis 15 parts, Indigo Naturalis 25 parts, Herba Centipedae 15 parts, Radix Bupleuri 60 parts, 60 parts, extra large Piao sheath, 25 parts, Poria, Folium Perillae 40 parts, bee pollen 160 parts, bran powder 1300 parts.
The described Chinese medicine composition preventing and treating newcastle disease is prepared from by following methods:
Step one, takes each raw material by weight;
Step 2, after the Radix Astragali taken, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Chrysanthemi, Fructus Crotonis, Indigo Naturalis, Herba Centipedae, Radix Bupleuri, Poria and Folium Perillae are mixed, add the water of this mixture quality 3 times, extract 12-18 hour at the temperature of about 80-90 DEG C after, filter and obtain water extraction filtrate;
Step 3, after the Cortex Moutan taken, Herba Houttuyniae, Radix Sanguisorbae being mixed, the volumetric concentration adding this mixture quality 1 times is the ethanol water of 50%, be placed in hermetic container, extract 18-24 hour under the condition of about 50-60 DEG C after, pulverized and made serosity, be alcohol extraction serosity;
Step 4, pulverizes rear mistake 60 mesh sieve respectively by the Fructus Hordei Germinatus taken, extra large Piao sheath and bee pollen, then mixes with bran powder, then mix with the water extraction filtrate of step 2, the alcohol extraction serosity of step 3, carry out cold drying after stirring, and obtains dry compound;
Step 5, pulverizes the mixed material of drying, is ground into 50-60 object powder, namely obtains the Chinese medicine composition preventing and treating newcastle disease of the present invention.
embodiment 4: safety testing
Acute toxicity test in mice: adopt the product of embodiment of the present invention 1-3 in 8% the ratio feedstuff that substitutes mice feed, Continuous Observation 14 days, duration of test has no dead and undue toxicity's reaction, off-test, Dissection test mice, observe liver,kidney,spleen, stomach, the heart, lung and intestinal, be showed no abnormal change.By standard of acute toxicity, this sample belongs to nontoxic level.
Murine chronic toxicity test: adopt the product of embodiment of the present invention 1-3 in 2% the ratio feedstuff that substitutes mice feed, feed continuously 90 days, result shows: the mice behavioral activity of the product of the embodiment of the present invention 1-3 that feeds is normal, fur is smooth, and Normal-weight increases, and drinking-water of ingesting is normal, hematology and blood parameters all fluctuate within normal range, bone marrow and routine urinalysis index all fluctuate within normal range, organize internal organs no abnormality seen, generally speaking have no toxicity reaction.
Chick feeding experiment: the feedstuff adopting the Chinese medicine composition of embodiment of the present invention 1-3 to replace 5% is fed, and feeds 50 days, chicken does not occur in this process and to be poisoned to death symptom, and the growth of chicken is more healthy, slaughters rear dissection and has no poisoning symptom.
From testing above, product of the present invention is safe, nontoxic.
embodiment 5: animal experiment
Choosing body weight is 0.6-0.75 kilogram, healthy broiler chicken 100 plumage, be divided into 5 groups, often organize 20 plumages, wherein organizing 1 adopts common broiler chicken feedstuff to feed, the feedstuff that group 2-4 adopts the Chinese medicine composition of embodiment of the present invention 1-3 to replace 0.2% carries out feeding the normal diet+0.8% of 99.2% (Chinese medicine composition), group 5 is contrast test group, the Chinese medicine composition of following comparative experimental example is adopted to replace feed additive normal diet+0.8% comparative experimental example of 99.2% (Chinese medicine composition) of 0.8%, after continuing to feed 2 months, to die of illness the lung homogenate liquid of chicken to chick injection newcastle, infect to simulate newcastle, continuous observation one month, the survival condition of record chick and growing state, concrete outcome is as follows:
Group 1(normal diet): survival rate is 30%, develops into newcastle very soon after inoculation, large quantities of chicken death, and the chick poor growth of survival, body weight is compared partially light;
Group 2(embodiment 1): survival rate is 90%, and the chicken of about 20% shows newcastle symptom after inoculation, rear section recovery from illness in 4-5 days, Mortality, and survival chick body weight is heavier;
Group 3(embodiment 2): survival rate is 85%, and the chicken of about 30% shows newcastle symptom after inoculation, rear section recovery from illness in 5-8 days, Mortality, and survival chick body weight is heavier;
Group 4(embodiment 3): survival rate is 95%, and the chicken of about 25% shows newcastle symptom after inoculation, rear section recovery from illness in 3-4 days, Mortality, and survival chick body weight is heavier;
Group 5(comparative example): survival rate is 55%, and the chicken of about 65% shows newcastle symptom after inoculation, rear section recovery from illness in 3-8 days, and Mortality, survival chick body weight is lighter.
Wherein the prescription of comparative example is: the Radix Astragali 250 parts, Rhizoma Coptidis 100 parts, the Rhizoma Atractylodis Macrocephalae 50 parts, Herba Houttuyniae 150 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 40 parts, Radix Sanguisorbae 40 parts, Flos Chrysanthemi 70 parts, 150 parts, Fructus Hordei Germinatus, Radix Bupleuri 50 parts, 50 parts, extra large Piao sheath, 20 parts, Poria, Folium Perillae 30 parts, bee pollen 150 parts, bran powder 1000 parts.Preparation method is with embodiment 1.
From above result of the test, product of the present invention has effective preventive effect for newcastle, the chicken of Long-term Feeding product of the present invention has good preventive effect for the Avian pneumo-encephalitis virus inoculated, and it can significantly improve the survival rate of chick, suppresses the expansion of epidemic situation.Further, compare the prescription of comparative example, the uniqueness that product of the present invention forms due to it, its successful is better than forming close product, achieves unforeseeable technique effect.
embodiment 6:
In chicken farm, Zhejiang, on the occasion of newcastle disease Onset, choose the chicken farm having newcastle to break out, this chicken farm take body weight as the broiler chicken of 0.75kg is master, and this chicken house has the chicken of 15% because infect newcastle death after diagnosing, the chicken of about 25% shows infection symptoms, the epidemic prevention of newcastle and treat extremely urgent, add the product of the embodiment of the present invention 1 according to the mass percentage of 2-5% in chicken feedstuff, after feeding 5 days, corresponding newcastle disease states is eased, substantially newcastle disease states is not had after feeding 10 days, after feeding 15 days, the epidemic disease symptom of chicken house all disappears, through statistics, after adopting product of the present invention to feed, the mortality rate of chicken house is only 5%, well below the mortality rate closing on chicken house.
Raw material of the present invention all can be commercially.Be only specific embodiments of the invention above, but the present invention is not limited thereto, the changes that any person skilled in the art can think of, all should drops within protection scope of the present invention.

Claims (5)

1. prevent and treat the Chinese medicine composition of newcastle disease for one kind, it is characterized in that, be made up of the raw material of following weight portion: Radix Astragali 250-300 part, Rhizoma Coptidis 100-150 part, Rhizoma Atractylodis Macrocephalae 50-80 part, Cortex Moutan 50-60 part, Herba Houttuyniae 150-200 part, Pseudobulbus Bletillae (Rhizoma Bletillae) 40-50 part, Radix Sanguisorbae 40-50 part, Flos Chrysanthemi 70-100 part, Fructus Hordei Germinatus 150-200 part, Fructus Crotonis 10-20 part, Indigo Naturalis 20-30 part, Herba Centipedae 10-20 part, Radix Bupleuri 50-70 part, extra large Piao sheath 50-70 part, Poria 20-30 part, Folium Perillae 30-50 part, bee pollen 150-170 part, bran powder 1000-1500 part.
2. the Chinese medicine composition preventing and treating newcastle disease according to claim 1, is characterized in that, preferably, is made up of the raw material of following weight portion: the Radix Astragali 250 parts, Rhizoma Coptidis 100 parts, the Rhizoma Atractylodis Macrocephalae 50 parts, Cortex Moutan 50 parts, Herba Houttuyniae 150 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 40 parts, Radix Sanguisorbae 40 parts, Flos Chrysanthemi 70 parts, 150 parts, Fructus Hordei Germinatus, Fructus Crotonis 10 parts, Indigo Naturalis 20 parts, Herba Centipedae 10 parts, Radix Bupleuri 50 parts, 50 parts, extra large Piao sheath, 20 parts, Poria, Folium Perillae 30 parts, bee pollen 150 parts, bran powder 1000 parts.
3. the Chinese medicine composition preventing and treating newcastle disease according to claim 1, is characterized in that, preferably, is made up of the raw material of following weight portion: the Radix Astragali 300 parts, Rhizoma Coptidis 150 parts, the Rhizoma Atractylodis Macrocephalae 80 parts, Cortex Moutan 60 parts, Herba Houttuyniae 200 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 50 parts, Radix Sanguisorbae 50 parts, Flos Chrysanthemi 100 parts, 200 parts, Fructus Hordei Germinatus, Fructus Crotonis 20 parts, Indigo Naturalis 30 parts, Herba Centipedae 20 parts, Radix Bupleuri 70 parts, 70 parts, extra large Piao sheath, 30 parts, Poria, Folium Perillae 50 parts, bee pollen 170 parts, bran powder 1500 parts.
4. the Chinese medicine composition preventing and treating newcastle disease according to claim 1, is characterized in that, preferably, is made up of the raw material of following weight portion: the Radix Astragali 280 parts, Rhizoma Coptidis 120 parts, the Rhizoma Atractylodis Macrocephalae 60 parts, Cortex Moutan 55 parts, Herba Houttuyniae 180 parts, Pseudobulbus Bletillae (Rhizoma Bletillae) 45 parts, Radix Sanguisorbae 45 parts, Flos Chrysanthemi 80 parts, 180 parts, Fructus Hordei Germinatus, Fructus Crotonis 15 parts, Indigo Naturalis 25 parts, Herba Centipedae 15 parts, Radix Bupleuri 60 parts, 60 parts, extra large Piao sheath, 25 parts, Poria, Folium Perillae 40 parts, bee pollen 160 parts, bran powder 1300 parts.
5. prepare a method of preventing and treating the Chinese medicine composition of newcastle disease according to claim 1, it is characterized in that, comprise the steps:
Step one, takes each raw material by weight;
Step 2, after the Radix Astragali taken, Rhizoma Coptidis, the Rhizoma Atractylodis Macrocephalae, Pseudobulbus Bletillae (Rhizoma Bletillae), Flos Chrysanthemi, Fructus Crotonis, Indigo Naturalis, Herba Centipedae, Radix Bupleuri, Poria and Folium Perillae are mixed, add the water of this mixture quality 3 times, extract 12-18 hour at the temperature of about 80-90 DEG C after, filter and obtain water extraction filtrate;
Step 3, after the Cortex Moutan taken, Herba Houttuyniae, Radix Sanguisorbae being mixed, the volumetric concentration adding this mixture quality 1 times is the ethanol water of 50%, be placed in hermetic container, extract 18-24 hour under the condition of about 50-60 DEG C after, pulverized and made serosity, be alcohol extraction serosity;
Step 4, pulverizes rear mistake 60 mesh sieve respectively by the Fructus Hordei Germinatus taken, extra large Piao sheath and bee pollen, then mixes with bran powder, then mix with the water extraction filtrate of step 2, the alcohol extraction serosity of step 3, carry out cold drying after stirring, and obtains dry compound;
Step 5, pulverizes the mixed material of drying, is ground into 50-60 object powder, namely obtains the Chinese medicine composition preventing and treating newcastle disease of the present invention.
CN201610034115.1A 2016-01-19 2016-01-19 Traditional Chinese medicine composition for preventing and treating newcastle disease and preparation method thereof Pending CN105535702A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103191240A (en) * 2013-04-17 2013-07-10 山东省农业科学院家禽研究所 Traditional Chinese veterinary medicine oral solution for preventing and treating viral diseases of poultry
CN104161877A (en) * 2013-08-30 2014-11-26 郑州后羿制药有限公司 Compound traditional Chinese medicine composition for preventing and treating newcastle disease and its preparation method and use

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103191240A (en) * 2013-04-17 2013-07-10 山东省农业科学院家禽研究所 Traditional Chinese veterinary medicine oral solution for preventing and treating viral diseases of poultry
CN104161877A (en) * 2013-08-30 2014-11-26 郑州后羿制药有限公司 Compound traditional Chinese medicine composition for preventing and treating newcastle disease and its preparation method and use

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