CN115154561B - Traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before parturition and having no peak in egg production and preparation method thereof - Google Patents

Traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before parturition and having no peak in egg production and preparation method thereof Download PDF

Info

Publication number
CN115154561B
CN115154561B CN202210895057.7A CN202210895057A CN115154561B CN 115154561 B CN115154561 B CN 115154561B CN 202210895057 A CN202210895057 A CN 202210895057A CN 115154561 B CN115154561 B CN 115154561B
Authority
CN
China
Prior art keywords
parts
chinese medicine
traditional chinese
medicine composition
infectious bronchitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN202210895057.7A
Other languages
Chinese (zh)
Other versions
CN115154561A (en
Inventor
郑佰有
李守林
夏乐文
曹博
王好
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Xia Lewen
Zheng Baiyou
Jilin Agricultural University
Original Assignee
Jilin Agricultural University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jilin Agricultural University filed Critical Jilin Agricultural University
Priority to CN202210895057.7A priority Critical patent/CN115154561B/en
Publication of CN115154561A publication Critical patent/CN115154561A/en
Application granted granted Critical
Publication of CN115154561B publication Critical patent/CN115154561B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/29Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296Epimedium
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/39Convolvulaceae (Morning-glory family), e.g. bindweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/43Cuscutaceae (Dodder family), e.g. Cuscuta epithymum or greater dodder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/54Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8998Hordeum (barley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Reproductive Health (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention relates to a traditional Chinese medicine composition for preventing chicken from producing kidney-type infectious bronchitis before parturition and producing eggs without peaks and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine compositions. Solves the technical problem that the phenomenon that the hen has kidney-shaped infectious bronchitis before starting, even if the disease is recovered, the hen always has no egg laying peak after starting, which causes great economic loss in the prior art. The traditional Chinese medicine composition provided by the invention comprises the following components in parts by weight: 150 parts of astragalus membranaceus, 80 parts of motherwort herb, 80 parts of angelica sinensis, 30 parts of ligusticum wallichii, 50 parts of epimedium herb, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of cortex phellodendri and 30 parts of radix scutellariae. The traditional Chinese medicine composition has low cost, easy preparation, no toxic or side effect and obvious curative effect, and clinical practice proves that the effective rate is 100 percent, and other alternatives such as the kallikrein, the antibiotics and the like are not ideal as compared with the effect of the invention.

Description

Traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before parturition and having no peak in egg production and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicine compositions, and in particular relates to a traditional Chinese medicine composition for preventing chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before parturition and a preparation method thereof.
Background
The laying hen has an egg laying peak period after starting for a period of time, and the egg laying peak period is a key period for the profit of the laying hen cultivation. If the laying peak is not reached for a long time after the laying hen is started, even the laying peak period is not reached, the benefit of laying hen cultivation is greatly affected.
Reasons for the fact that laying hens cannot reach an egg laying peak for a long time after opening the egg laying period even do not reach the egg laying peak period include feed reasons, environmental factors, medication problems, disease factors and the like, wherein the disease factors are the most common, and infectious bronchitis of chickens is a frequently occurring disease.
If the laying hen suffers from infectious bronchitis before starting, even if the disease is recovered, the phenomenon of no egg laying peak period often occurs after starting, which causes great economic loss. The infectious bronchitis is clinically manifested by various types, such as respiratory infectious bronchitis, kidney-type infectious bronchitis, adenogastric infectious bronchitis, reproductive infectious bronchitis and the like. Among the many types of nephropathogenic avian infectious bronchitis is one of the most common and primitive types.
In the case of clinically treating kidney-type infectious bronchitis, antibiotics are used for treatment, and traditional Chinese medicine formulas are also used for treatment, but the traditional Chinese medicine formulas are not based on body conditioning, and if the physiological state of the body is not adjusted in advance in the later stage of the disease, the later-stage laying rate is difficult to rise to the peak.
The method for the farms to cope with the peak without egg laying or delay the peak with egg laying adopts the powder with the formula as follows: giant knotweed rhizome, red sage root, dodder seed, chinese angelica, szechuan lovage rhizome, oyster, garden burnet root and desertliving cistanche. The kaleidoscope has a certain effect for treating low laying rate, but is not specially aimed at clinical cases of no egg laying peak caused by kidney-type infectious bronchitis of chickens, and has poor effect.
Disclosure of Invention
The invention aims to solve the technical problem that the prior art has kidney-shaped infectious bronchitis before starting, even if the disease is recovered, the phenomenon of no egg laying peak occurs after starting, and serious economic loss is caused, and provides a traditional Chinese medicine composition for preventing the chicken from producing eggs without peak after the kidney-shaped infectious bronchitis before starting and a preparation method thereof.
In order to achieve the above purpose, the following technical scheme is adopted:
the invention provides a traditional Chinese medicine composition for preventing chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before parturition, which comprises the following components in parts by weight:
150 parts of astragalus membranaceus, 80 parts of motherwort herb, 80 parts of angelica sinensis, 30 parts of ligusticum wallichii, 50 parts of epimedium herb, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of cortex phellodendri and 30 parts of radix scutellariae.
The invention also provides a preparation method of the traditional Chinese medicine composition for preventing the chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before beginning production, which comprises the following steps: weighing the components according to the proportion, crushing, soaking in water, decocting and extracting for a plurality of times, combining the extracting solutions, and concentrating to obtain the traditional Chinese medicine composition for preventing the chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before beginning to produce.
Preferably, the time of soaking in water is 30min.
Preferably, the water addition amount is 3-5 times of the total mass of each component.
Preferably, the process of decocting and extracting for a plurality of times is as follows: decocting with water for 30min, filtering to obtain first extractive solution and residue, adding water into residue, decocting with water for 30min to obtain second extractive solution, filtering, removing residue, and mixing the first and second extractive solutions.
More preferably, the amount of the re-added water is 3 to 5 times the total mass of each component.
Preferably, the crude drug is concentrated to 1.5g/ml.
The principle of the invention is as follows: the middle veterinarian considers that the kidney is the congenital origin, and the kidney not only has the effect of main water metabolism, but also can main bones and marrow, and has close relation with the growth and development of animals and reproduction. The kidney function of the kidney-shaped infectious bronchitis is damaged and the reproductive system is destroyed, so that the traditional Chinese medicine is added in time for conditioning in the recovery period of the occurrence of the kidney-shaped infectious bronchitis, the influence of the kidney-shaped infectious bronchitis on the reproductive system can be reduced, and the aim of preventing the egg laying without peak after the kidney-shaped infectious bronchitis is achieved. The traditional Chinese medicine composition has good curative effect in the recovery adjustment period after the diseases of the chicken suffering from the kidney-type infectious bronchitis.
Compared with the prior art, the invention has the beneficial effects that:
the traditional Chinese medicine composition for preventing chicken from producing eggs without peak after onset of kidney-type infectious bronchitis has the advantages of low cost, easy preparation, no toxic or side effect, obvious curative effect, 100% of effective rate, less ideal effect than other alternatives such as kaleidosis, antibiotics and the like.
Detailed Description
For a further understanding of the present invention, preferred embodiments of the invention are described below, but it is to be understood that these descriptions are merely intended to illustrate further features and advantages of the invention, and are not limiting of the claims of the invention.
The invention relates to a traditional Chinese medicine composition for preventing chicken from producing kidney-type infectious bronchitis before parturition and producing eggs without peaks, which comprises the following components in parts by weight: 150 parts of astragalus membranaceus, 80 parts of motherwort herb, 80 parts of angelica sinensis, 30 parts of ligusticum wallichii, 50 parts of epimedium herb, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of cortex phellodendri and 30 parts of radix scutellariae. Or may consist of only the above components.
The preparation method of the traditional Chinese medicine composition for preventing the chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before parturition comprises the following steps: weighing the components according to the proportion, crushing, soaking in water, decocting and extracting for a plurality of times, combining the extracting solutions, and concentrating to obtain the traditional Chinese medicine composition for preventing the chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before beginning to produce.
In the technical scheme, the soaking time of the water is 30min.
In the technical scheme, the water adding amount is 3-5 times of the total mass of each component.
In the technical scheme, the process of decocting and extracting for a plurality of times is as follows: decocting with water for 30min, filtering to obtain first extractive solution and residue, adding water, decocting with water for 30min to obtain second extractive solution, filtering, removing residue, and mixing the first and second extractive solutions.
In the technical scheme, the water is added in an amount which is 3-5 times of the total mass of each component.
In the above technical scheme, the crude drug is concentrated to 1.5g/ml.
The traditional Chinese medicine composition for preventing chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before parturition has the drinking amount of 1ml per day in clinical application, and 5 days is a treatment course after one-time drinking.
The traditional Chinese medicine composition for preventing chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before beginning to produce comprises the following components: the composition uses astragalus root to tonify middle-jiao and qi, tonify qi and promote blood generation. Astragalus mongholicus is also a common medicament for improving disease resistance in veterinary clinic. Herba Leonuri is specialized in blood system, and has the main actions of promoting blood circulation, promoting diuresis, tonifying without stagnation, and promoting blood circulation without severity. Chinese angelica regulates qi and blood, and makes qi and blood enter each other. Ligusticum wallichii has no place to activate blood. Epimedium can tonify kidney yang and dehumidify. Semen Cuscutae is used for nourishing liver and kidney and replenishing essence and blood. Ramulus Cinnamomi is used for warming kidney yang and dispersing blood vessel. Fructus crataegi, massa Medicata Fermentata, and fructus Hordei Germinatus are used for coordinating intestines and stomach, promoting digestion, and promoting recovery of digestive function. Blackberry lily, platycodon root and radix isatidis are used for conditioning respiratory symptoms caused by infectious bronchitis, and can eliminate phlegm, relieve cough and asthma, and clear away heat and toxic materials. Cortex Phellodendri and Scutellariae radix are used for removing residual hot gas and moisture from the lower coke. The formula regulates the functions of damaged kidneys and reproductive organs mainly by regulating qi and blood and tonifying liver and kidney. And then further eliminating respiratory symptoms (blackberry lily, platycodon root and radix isatidis) accompanied with later stage of diseases, digestive tract symptoms (phellodendron bark and baical skullcap root), and also solving the problems of inappetence and dyspepsia caused by diseases (hawthorn, medicated leaven and malt). The composition has low cost, easy preparation, no toxic or side effect and obvious curative effect, and the clinical practice proves that the effective rate is 100%.
The terms used in the present invention generally have meanings commonly understood by those of ordinary skill in the art unless otherwise indicated. In order to enable those skilled in the art to better understand the technical solutions of the present invention, the present invention will be described in further detail with reference to examples.
In the following examples, various processes and methods, which are not described in detail, are conventional methods well known in the art. Materials, reagents, devices, instruments, equipment and the like used in the examples described below are commercially available unless otherwise specified.
The invention is further illustrated below with reference to examples.
Example 1
The traditional Chinese medicine composition for preventing chicken from suffering kidney-type infectious bronchitis before parturition and having no peak in egg production comprises, by weight, 150 parts of astragalus membranaceus, 80 parts of motherwort herb, 80 parts of Chinese angelica, 30 parts of ligusticum wallichii, 50 parts of epimedium herb, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of cortex phellodendri and 30 parts of radix scutellariae.
The preparation method of the traditional Chinese medicine composition for preventing the chicken from producing kidney-type infectious bronchitis and producing eggs without peaks comprises the following steps: weighing the components according to the proportion, crushing, adding 3 times of water, soaking for 30min, putting into a traditional Chinese medicine decoction pot, boiling with water for 30min with low fire, filtering, removing residues, adding 3 times of water into the residues, boiling with low fire for 30min after boiling with water, filtering, removing residues, mixing the two decoction liquids, and concentrating to obtain the traditional Chinese medicine composition containing 1.5g/ml of crude drugs, wherein the traditional Chinese medicine composition is used for preventing the occurrence of kidney-type infectious bronchitis in chickens before the chickens develop and has no peak in egg laying.
Experiments were carried out on the effect of the traditional Chinese medicine composition prepared in example 1 on preventing the occurrence of peak in eggs after the onset of kidney-type infectious bronchitis in chickens.
1.1 Experimental methods
The method is characterized in that 6000 large sea-sky-brown groups with the age of 85 days are taken, chickens only have the phenomena of cough, listlessness, remarkably reduced feed intake, messy feathers, improved water intake, remarkably reduced production performance, diarrhea and the like, infectious bronchitis viruses which are typical kidney-type infectious bronchitis diseases are diagnosed by a sectioning and PCR method, the sick chicken groups are randomly divided into three groups (2000 groups) which are respectively an experimental group, an egg-stimulating powder group and a control group, and specific grouping conditions and main quality methods are shown in table 1.
TABLE 1 grouping conditions and primary treatment methods
Wherein, the Chinese medicine powder of the kaleidoscope is prepared by the following method: is prepared from rhizoma Polygoni Cuspidati 100g, saviae Miltiorrhizae radix 80g, semen Cuscutae 60g, radix Angelicae sinensis 60g, rhizoma Ligustici Chuanxiong 60g, concha Ostreae 60g, radix Sangusorbae 50g, cistanchis herba 60g, flos Caryophylli 20g and radix Paeoniae alba 50g (formula is from Chinese veterinary drug dictionary 2015 edition), by pulverizing, sieving, and mixing.
1.2 determination of efficacy
Standard of efficacy: the standard of curative effect is mainly based on whether the main clinic of the chicken disappears, and the curative effect, the arrival time of the egg laying peak period and the egg laying rate of the peak period are observed after one treatment course, and the specific curative effect is divided into three stages.
And (3) curing: all symptoms of kidney-type infectious bronchitis disappear
Improvement: partial disappearance of symptoms of kidney-type infectious bronchitis
Invalidation: no obvious change
In addition to the above criteria, the therapeutic effect was evaluated from the age of the day of the later peak egg laying period and the highest egg laying rate. The sea orchid brown eggs are generally seen at 130-140 days old, the laying rate at 210 days old reaches more than 80%, and the laying peak at 250 days old, namely the laying rate is more than 90%.
1.3 experimental results
6000 chickens were treated by dividing into three groups and using different schemes, and the treatment effect of each group after one treatment course is shown in table 2.
Table 2 therapeutic effects of various treatment regimens
As can be seen from table 2, the experimental group and the kallikrein group have different therapeutic effects on nephropathogenic infectious bronchitis, wherein the experimental group has better therapeutic effects than the kallikrein group (P < 0.01). The invention has the advantages of not only embodying the cure rate, but also being capable of preventing the serious clinical phenomenon that the egg laid after the nephroinfectious bronchitis has no peak. The presence or absence of the peak laying rate and the delay greatly affect the economic benefit.
Practice proves that the traditional Chinese medicine composition provided by the invention is accurate and reasonable in compatibility. The traditional Chinese medicine composition can not only relieve the clinical symptoms of the kidney-type infectious bronchitis, but also give consideration to the invisible loss of no egg laying peak caused by the disease in the later period.
It is apparent that the above embodiments are merely examples for clarity of illustration and are not limiting examples. Other variations or modifications of the above teachings will be apparent to those of ordinary skill in the art. It is not necessary here nor is it exhaustive of all embodiments. And obvious variations or modifications thereof are contemplated as falling within the scope of the present invention.

Claims (7)

1. The traditional Chinese medicine composition for preventing chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before beginning production is characterized by being prepared from the following raw materials in parts by weight:
150 parts of astragalus membranaceus, 80 parts of motherwort herb, 80 parts of angelica sinensis, 30 parts of ligusticum wallichii, 50 parts of epimedium herb, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of cortex phellodendri and 30 parts of radix scutellariae.
2. The method for preparing the traditional Chinese medicine composition for preventing the peak-free egg production after the pre-partum kidney-type infectious bronchitis of chickens, which is disclosed in claim 1, is characterized by comprising the following steps:
weighing the components according to the proportion, crushing, soaking in water, decocting and extracting for a plurality of times, combining the extracting solutions, and concentrating to obtain the traditional Chinese medicine composition for preventing the chicken from producing eggs without peaks after suffering from kidney-type infectious bronchitis before beginning to produce.
3. The method for preparing the traditional Chinese medicine composition for preventing the occurrence of peak in egg production after the onset of nephropathogenic infectious bronchitis in chickens according to claim 2, wherein the time for soaking in water is 30min.
4. The method for preparing a traditional Chinese medicine composition for preventing the occurrence of peak egg production after the onset of nephropathogenic infectious bronchitis in chickens according to claim 2, wherein the water addition amount is 3-5 times of the total mass of each component.
5. The method for preparing the traditional Chinese medicine composition for preventing the occurrence of peak in eggs laid after the onset of nephropathogenic infectious bronchitis in chickens according to claim 2, wherein the steps of decocting and extracting for a plurality of times and combining the extracting solutions are as follows: decocting with water for 30min, filtering to obtain first extractive solution and residue, adding water into residue, decocting with water for 30min to obtain second extractive solution, filtering, removing residue, and mixing the first and second extractive solutions.
6. The method for preparing a traditional Chinese medicine composition for preventing the occurrence of peak in egg production after the onset of nephropathogenic infectious bronchitis in chickens according to claim 5, wherein the amount of the added water is 3-5 times of the total mass of each component.
7. The method for preparing a traditional Chinese medicine composition for preventing the occurrence of peak in egg production after the onset of nephropathogenic infectious bronchitis in chickens according to claim 2, wherein the composition is concentrated to 1.5g/ml of crude drug.
CN202210895057.7A 2022-07-28 2022-07-28 Traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before parturition and having no peak in egg production and preparation method thereof Active CN115154561B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210895057.7A CN115154561B (en) 2022-07-28 2022-07-28 Traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before parturition and having no peak in egg production and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210895057.7A CN115154561B (en) 2022-07-28 2022-07-28 Traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before parturition and having no peak in egg production and preparation method thereof

Publications (2)

Publication Number Publication Date
CN115154561A CN115154561A (en) 2022-10-11
CN115154561B true CN115154561B (en) 2023-10-20

Family

ID=83496823

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210895057.7A Active CN115154561B (en) 2022-07-28 2022-07-28 Traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before parturition and having no peak in egg production and preparation method thereof

Country Status (1)

Country Link
CN (1) CN115154561B (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101670021A (en) * 2009-09-17 2010-03-17 天津生机集团股份有限公司 Traditional Chinese medicine composite for treating egg laying performance reduction of layer and preparation method thereof
CN103191263A (en) * 2013-04-02 2013-07-10 河北农业大学 Traditional Chinese medicine preparation for preventing and treating kidney-type infectious bronchitis of broiler chicken and preparation method thereof
CN104689160A (en) * 2013-12-04 2015-06-10 天津嘉瑞生物科技有限公司 Traditional Chinese medicine composition for improving egg laying rate of poultry and preparation method thereof
KR20160108046A (en) * 2015-03-06 2016-09-19 건국대학교 산학협력단 An Attenuated Infectious bronchitis virus and An Infectious bronchitis vaccine using the same
CN106924693A (en) * 2017-02-23 2017-07-07 张宪利 It is a kind of to treat pharmaceutical composition of avian nephropathogenic infectious bronchitis and preparation method thereof
CN110393753A (en) * 2019-08-28 2019-11-01 安徽农业大学 A kind of Chinese medicine composition and preparation method for preventing and treating Egg Production of Laying Hens syndrome

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101670021A (en) * 2009-09-17 2010-03-17 天津生机集团股份有限公司 Traditional Chinese medicine composite for treating egg laying performance reduction of layer and preparation method thereof
CN103191263A (en) * 2013-04-02 2013-07-10 河北农业大学 Traditional Chinese medicine preparation for preventing and treating kidney-type infectious bronchitis of broiler chicken and preparation method thereof
CN104689160A (en) * 2013-12-04 2015-06-10 天津嘉瑞生物科技有限公司 Traditional Chinese medicine composition for improving egg laying rate of poultry and preparation method thereof
KR20160108046A (en) * 2015-03-06 2016-09-19 건국대학교 산학협력단 An Attenuated Infectious bronchitis virus and An Infectious bronchitis vaccine using the same
CN106924693A (en) * 2017-02-23 2017-07-07 张宪利 It is a kind of to treat pharmaceutical composition of avian nephropathogenic infectious bronchitis and preparation method thereof
CN110393753A (en) * 2019-08-28 2019-11-01 安徽农业大学 A kind of Chinese medicine composition and preparation method for preventing and treating Egg Production of Laying Hens syndrome

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李景峰等.《蛋鸡常见病毒病及诊断规范》.2018,第98页第1段. *

Also Published As

Publication number Publication date
CN115154561A (en) 2022-10-11

Similar Documents

Publication Publication Date Title
CN102846866B (en) Chinese medicine composition for prevention and control of porcine circovirus disease and preparation method thereof
CN101507762B (en) Veterinary medicine for treating colibacillosis and white dysentery
CN110624094A (en) Traditional Chinese medicine composition for treating and preventing African swine fever
CN105641149A (en) Toxin-removing oral liquid containing fineleaf schizonepeta herbs and divaricate saposhnikovia roots and preparation method of oral liquid
CN102397372A (en) Medicinal composition and pharmaceutical preparation and application thereof to treating irritable bowel syndrome
CN102641366A (en) Traditional Chinese medicine composition for preventing and treating proventriculitis and gizzard erosion of poultry
CN115154561B (en) Traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before parturition and having no peak in egg production and preparation method thereof
CN106036083A (en) Immunity-improving piglet feed additive
CN102370852A (en) Chinese herbal medicine for treating chronic colitis
CN114886961A (en) Traditional Chinese medicine composition for treating/preventing avian gout and preparation method and application thereof
CN104435626A (en) Traditional Chinese medicine oral liquid for treating viral diseases of livestock and poultry and preparation method of traditional Chinese medicine oral liquid
CN113559230A (en) Traditional Chinese medicine composition for preventing and treating broiler ascites syndrome
CN111789932A (en) Compound traditional Chinese medicine preparation for treating swine pneumonia syndrome and preparation method thereof
CN104001113A (en) Oncologic nursing traditional Chinese medicine composition and preparation method thereof
CN110215485A (en) Chinese medicine composition and preparation method thereof for treating diabetes skin ulcer
CN115068546B (en) Traditional Chinese veterinary medicine oral liquid for preventing and treating poultry liver diseases and application thereof
CN104096073A (en) Traditional Chinese medicine composition for treating male infertility and preparation method for same
CN111920898B (en) Antiviral prescription and preparation method thereof
CN103784736A (en) Medicine composition for treating pregnancy toxaemia of equus animals
CN108042691A (en) A kind of Chinese medicine additive for preventing snakehead Ascites Disease
CN101954033B (en) Chinese traditional medicine composition for treating diseases of digestive tracts and respiratory tracts of chickens and preparation method thereof
CN107929593B (en) Medicament for treating children cough
CN105125800A (en) Traditional Chinese medicine oral liquid for treating proventriculitis and muscular stomach inflammation of chickens
CN105194579A (en) Medicament for preventing and treating lamb dysentery
CN110448616A (en) A kind of production method of traditional Chinese medicine formula that treating five black infectious laryngotracheitis of chickens

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20221115

Address after: 134600 group 42, Sixth Committee, Sengong street, Linjiang City, Baishan City, Jilin Province

Applicant after: Zheng Baiyou

Applicant after: Xia Lewen

Applicant after: JILIN AGRICULTURAL University

Address before: 134600 group 42, Sixth Committee, Sengong street, Linjiang City, Baishan City, Jilin Province

Applicant before: Zheng Baiyou

GR01 Patent grant
GR01 Patent grant