CN115154561A - Traditional Chinese medicine composition for preventing chicken from having no peak egg laying after suffering from nephropathogenic infectious bronchitis before onset of parturition and preparation method thereof - Google Patents

Traditional Chinese medicine composition for preventing chicken from having no peak egg laying after suffering from nephropathogenic infectious bronchitis before onset of parturition and preparation method thereof Download PDF

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CN115154561A
CN115154561A CN202210895057.7A CN202210895057A CN115154561A CN 115154561 A CN115154561 A CN 115154561A CN 202210895057 A CN202210895057 A CN 202210895057A CN 115154561 A CN115154561 A CN 115154561A
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chinese medicine
traditional chinese
infectious bronchitis
medicine composition
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CN115154561B (en
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郑佰有
李守林
夏乐文
曹博
王好
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Xia Lewen
Zheng Baiyou
Jilin Agricultural University
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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Abstract

The invention relates to a traditional Chinese medicine composition for preventing chicken from suffering kidney-type infectious bronchitis before onset of labor and causing no egg laying peak after the chicken suffers from kidney-type infectious bronchitis and a preparation method thereof, belonging to the technical field of traditional Chinese medicine compositions. Solves the technical problem that the laying hen suffers from kidney type chicken infectious bronchitis before the laying hen is laid, even if the disease is recovered, the phenomenon of egg laying peak period after the laying hen is laid frequently is caused, and the major economic loss is caused. The traditional Chinese medicine composition comprises the following components in parts by weight: 150 parts of astragalus, 80 parts of motherwort, 80 parts of angelica, 30 parts of ligusticum wallichii, 50 parts of epimedium, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of golden cypress and 30 parts of scutellaria baicalensis. The traditional Chinese medicine composition has the advantages of low cost, easy preparation, no toxic or side effect and obvious curative effect, the clinical practice proves that the effective rate is 100%, and the other alternative schemes of egg activating powder, antibiotics and the like are not as good as the effect of the traditional Chinese medicine composition.

Description

Traditional Chinese medicine composition for preventing chicken from suffering kidney-type infectious bronchitis before onset of labor and causing no egg laying peak after chicken suffers from kidney-type infectious bronchitis and preparation method thereof
Technical Field
The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for preventing chicken from having no peak egg laying after suffering from nephropathogenic infectious bronchitis before laying and a preparation method thereof.
Background
The laying hens have an egg laying peak period for a period of time after the laying hens are started, and the egg laying peak period is a key period for profitability of the laying hens. If the laying peak cannot be reached or even not reached after the laying hens are laid, the benefit of laying hen breeding is greatly influenced.
The reasons that the laying hens cannot reach the laying peak for a long time after the laying hens are started and even do not reach the laying peak comprise feed reasons, environmental factors, medication problems, disease factors and the like, wherein the disease factors are the most common, and the infectious bronchitis of the laying hens is a frequently encountered disease.
If the laying hens suffer from infectious bronchitis before the laying period, even if the disease is recovered, the phenomenon of egg-laying free peak time often occurs after the laying period, and great economic loss is caused. The avian infectious bronchitis is clinically manifested by various types, such as respiratory infectious bronchitis, renal infectious bronchitis, glandular stomach infectious bronchitis, reproductive infectious bronchitis, and the like. Nephrotic avian infectious bronchitis is the more common and most primitive of the many types.
In the case of clinically treating the nephropathogenic avian infectious bronchitis, antibiotics and traditional Chinese medicine formulas are used for treating the nephropathogenic avian infectious bronchitis, but the antibiotics and the traditional Chinese medicine formulas are not based on conditioning the organism, and the laying rate hardly rises to a peak in the later period if the physiological state of the organism is not adjusted in advance in the later period of the disease.
The method for the farm to deal with the peak of no egg laying or delay the peak of egg laying adopts the egg activating powder, and the formula of the egg activating powder is as follows: giant knotweed rhizome, red sage root, dodder seed, angelica, szechuan lovage rhizome, oyster shell, garden burnet root and desertliving cistanche. The egg activating powder has a certain effect on treating low laying rate, but is not specially used for the clinical case of the peak of no laying eggs caused by the nephropathogenic avian infectious bronchitis, and has poor effect.
Disclosure of Invention
The invention aims to solve the technical problem that in the prior art, when the chicken suffer from the kidney-type infectious bronchitis before the onset of labor, even if the disease recovers, the phenomenon of no egg-laying peak often occurs after the onset of labor, so that the great economic loss is caused, and provides a traditional Chinese medicine composition for preventing the chicken from suffering from the kidney-type infectious bronchitis before the onset of labor and having no egg-laying peak after the chicken suffer from the kidney-type infectious bronchitis before the onset of labor and a preparation method thereof.
In order to realize the purpose, the following technical scheme is adopted:
the invention provides a traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before onset of parturition and causing no peak egg laying, which comprises the following components in parts by weight:
150 parts of astragalus, 80 parts of motherwort, 80 parts of angelica, 30 parts of ligusticum wallichii, 50 parts of epimedium, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of golden cypress and 30 parts of scutellaria baicalensis.
The invention also provides a preparation method of the traditional Chinese medicine composition for preventing chicken from having kidney-type infectious bronchitis before onset of labor and having no peak egg laying, which comprises the following steps: weighing the components according to the proportion, crushing, soaking in water, decocting and extracting for multiple times, combining the extracting solutions, and concentrating to obtain the traditional Chinese medicine composition for preventing chicken from having kidney-type infectious bronchitis before laying and having no peak egg laying.
Preferably, the soaking time in water is 30min.
Preferably, the water addition amount is 3-5 times of the total mass of each component.
Preferably, the process of decocting and extracting for multiple times is as follows: decocting in water for 30min, filtering to obtain first extractive solution and residue, adding water to the residue, decocting in water for 30min to obtain second extractive solution, filtering, removing residue, and mixing the first and second extractive solutions.
More preferably, the amount of the further water is 3 to 5 times of the total mass of the components.
Preferably, the concentration is made to 1.5g/ml of crude drug.
The principle of the invention is as follows: the kidney is the congenital foundation, and has the functions of governing water metabolism, bone and marrow generation, and has close relation with the growth, development and reproduction of animals. The nephropathogenic infectious bronchitis causes damage to kidney function and damages reproductive system, so that the influence of the nephropathogenic infectious bronchitis on the reproductive system can be reduced by adding traditional Chinese medicine for conditioning in time in the recovery period of the nephropathogenic infectious bronchitis, and the aim of preventing the nephropathogenic infectious bronchitis from laying no peak is fulfilled. The traditional Chinese medicine composition has good conditioning effect in the recovery and regulation period after the chicken suffers from the disease of the nephropathogenic infectious bronchitis.
Compared with the prior art, the invention has the following beneficial effects:
the traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before onset of labor, which is disclosed by the invention, has the advantages of low cost, easiness in preparation, no toxic or side effect and remarkable curative effect, clinical practice proves that the effective rate is 100%, and other alternative schemes such as egg activating powder and antibiotics are not as ideal as the effect of the traditional Chinese medicine composition.
Detailed Description
For a further understanding of the invention, reference will now be made to the preferred embodiments of the invention, but it is to be understood that the description is intended to illustrate further features and advantages of the invention, and not to limit the scope of the claims.
The invention relates to a traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before onset of labor and producing no peak egg, which comprises the following components in parts by weight: 150 parts of astragalus, 80 parts of motherwort, 80 parts of angelica, 30 parts of ligusticum wallichii, 50 parts of epimedium, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of golden cypress and 30 parts of scutellaria baicalensis. It may consist of only the above-mentioned components.
The preparation method of the traditional Chinese medicine composition for preventing chicken from suffering kidney-type infectious bronchitis before onset of labor and causing no peak egg laying comprises the following steps: weighing the components according to the proportion, crushing, soaking in water, decocting and extracting for multiple times, combining the extracting solutions, and concentrating to obtain the traditional Chinese medicine composition for preventing chicken from having kidney-type infectious bronchitis before laying and having no peak egg laying.
In the technical scheme, the soaking time in water is 30min.
In the technical scheme, the water adding amount is 3-5 times of the total mass of the components.
In the technical scheme, the process of decocting and extracting for multiple times is as follows: decocting in water for 30min, filtering to obtain first extractive solution and residue, adding water, decocting in water for 30min to obtain second extractive solution, filtering, removing residue, and mixing the first and second extractive solutions.
In the technical scheme, the amount of the added water is 3-5 times of the total mass of the components.
In the above technical scheme, the crude drug is concentrated to 1.5g/ml.
The traditional Chinese medicine composition for preventing chicken from having kidney-type infectious bronchitis before onset of labor and then having no peak egg laying is clinically applied, the drinking amount of each chicken is 1ml per day, one time of drinking is finished, and 5 days are a treatment course.
The traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before onset of labor and producing no peak egg is prepared from the following components in parts by weight: the formula mainly uses the astragalus root for tonifying middle-jiao and Qi, and tonifying Qi and generating blood. The astragalus is also a common medicament for improving the disease resistance clinically for animals. Motherwort herb is specialized in blood system and mainly has the main functions of promoting blood circulation, inducing diuresis, tonifying without stagnation and promoting blood circulation without drastic action. Dang Gui regulates qi and blood, so that qi and blood can enter all kinds of qi and blood. Chuan Xiong can not promote blood circulation. Epimedium herb can tonify kidney yang and remove dampness. Semen Cuscutae can tonify liver and kidney, and nourish essence and blood. Gui Zhi is used to warm kidney yang and conduct blood vessels. The hawthorn, the medicated leaven and the malt are used for coordinating intestines and stomach, promoting digestion and promoting the recovery of digestive function. Belamcanda chinensis, platycodon grandiflorum and isatis root are used for conditioning respiratory symptoms caused by infectious bronchitis, and can eliminate phlegm, relieve cough and asthma and clear away heat and toxic materials. Phellodendron bark and scutellaria root are used to remove residual heat and moisture from lower energizer. The formula regulates the functions of the damaged kidney and reproductive organs mainly by regulating qi and blood and tonifying liver and kidney. And can further eliminate respiratory symptoms (rhizoma Belamcandae, radix Platycodi, and radix Isatidis) and digestive tract symptoms (cortex Phellodendri and Scutellariae radix) accompanied by late stage diseases, and also solve the problems of anorexia and dyspepsia (fructus crataegi, massa Medicata Fermentata, and fructus Hordei Germinatus) caused by diseases. The formula has the advantages of low cost, easy preparation, no toxic or side effect and obvious curative effect, and clinical practice proves that the effective rate is 100%.
The terms used in the present invention generally have meanings commonly understood by those of ordinary skill in the art, unless otherwise specified. In order to make those skilled in the art better understand the technical solution of the present invention, the present invention will be further described in detail with reference to the following embodiments.
In the following examples, various procedures and methods not described in detail are conventional methods well known in the art. Materials, reagents, devices, instruments, apparatuses and the like used in the following examples are commercially available unless otherwise specified.
The present invention is further illustrated by the following examples.
Example 1
The traditional Chinese medicine composition for preventing chicken from laying no peak after suffering from kidney type infectious bronchitis before childbirth comprises, by weight, 150 parts of astragalus membranaceus, 80 parts of motherwort, 80 parts of angelica sinensis, 30 parts of ligusticum wallichii, 50 parts of herba epimedii, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of golden cypress and 30 parts of scutellaria baicalensis.
The preparation method of the traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before onset of labor and having no egg laying peak comprises the following steps: weighing the components according to the proportion, crushing, adding 3 times of water for soaking for 30min, putting into a traditional Chinese medicine decocting pot, boiling with water, decocting with slow fire for 30min, filtering, removing medicine residues, adding 3 times of water into medicine residues, boiling with slow fire for 30min, filtering, removing medicine residues, mixing the two decocted medicine liquids, and concentrating to 1.5g/ml of crude medicine to obtain the traditional Chinese medicine composition for preventing chicken from suffering from kidney type infectious bronchitis before laying eggs and having no peak after laying eggs.
An experiment was performed on the effect of the Chinese medicinal composition for preventing chicken from having a peak egg production after suffering from nephropathogenic infectious bronchitis before onset of labor, prepared in example 1.
1.1 Experimental methods
6000-day-old large herd of cymbidium bicolor is taken, and the phenomenon that the chickens have cough, listlessness, remarkably reduced feed intake, disordered feathers, improved water intake, remarkably reduced production performance, diarrhea and the like is caused, infectious bronchitis viruses are diagnosed by a caesarean section and a PCR method, the infected chicken herd is a typical nephrotic infectious bronchitis, the infected chicken herd is randomly divided into three groups (2000 per group), namely an experimental group, an egg-stimulating group and a control group, and the specific grouping condition and the main quality method are shown in Table 1.
TABLE 1 grouping of conditions and main treatment methods
Figure BDA0003769033650000051
The egg activating powder traditional Chinese medicine powder is prepared by the following method: pulverizing rhizoma Polygoni Cuspidati 100g, saviae Miltiorrhizae radix 80g, semen Cuscutae 60g, radix Angelicae sinensis 60g, rhizoma Ligustici Chuanxiong 60g, concha Ostreae 60g, radix Sangusorbae 50g, cistanchis herba 60g, flos Caryophylli 20g and radix Paeoniae alba 50g (prescription from Chinese animal pharmacopoeia 2015 edition), sieving, and mixing.
1.2 therapeutic efficacy determination
The curative effect standard is as follows: the curative effect standard is mainly based on whether the main clinic of the chicken disappears, the curative effect, the arrival time of the egg laying peak period and the egg laying rate of the peak period are observed after the medicine is taken for one treatment period, and the specific curative effect is divided into three levels.
And (3) curing: the symptoms of nephropathogenic infectious bronchitis disappear completely
Improvement: partial disappearance of symptoms of nephropathogenic infectious bronchitis
And (4) invalidation: without obvious change
In addition to the above criteria, the treatment effect is evaluated from the day age of the later egg laying peak period and the maximum egg laying rate. The Hailanhua generally appears eggs at the age of 130-140 days, the laying rate reaches more than 80% at the age of 210 days, the laying peak reaches at the age of 250 days, namely the laying rate is more than 90%.
1.3 results of the experiment
6000 chickens were treated by three groups using different regimens, and the treatment effect of each group after one treatment course is shown in table 2.
TABLE 2 therapeutic Effect of the various treatment regimens
Figure BDA0003769033650000061
As can be seen from Table 2, the experimental group and the Jieyansan group have different treatment effects on the kidney-type infectious bronchitis, wherein the treatment effect of the experimental group is better and is obviously higher than that of the Jieyansan group (P < 0.01). The invention has the advantages of not only being reflected in the cure rate, but also being capable of preventing the serious clinical phenomenon of egg-laying peak after the nephropathogenic infectious bronchitis. The existence and delay of the peak of laying rate greatly affects the economic benefit.
Practice proves that the traditional Chinese medicine composition is accurate and reasonable in compatibility. The traditional Chinese medicine composition can relieve the clinical symptoms of treating the nephropathogenic infectious bronchitis and also can give consideration to the invisible loss of the peak of no egg laying caused by the disease in the later period.
It should be understood that the above-described embodiments are merely examples for clarity of description and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither necessary nor exhaustive of all embodiments. And obvious variations or modifications of the invention may be made without departing from the scope of the invention.

Claims (7)

1. The traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before onset of labor and causing no egg laying peak is characterized by comprising the following components in parts by weight:
150 parts of astragalus, 80 parts of motherwort, 80 parts of angelica, 30 parts of ligusticum wallichii, 50 parts of epimedium, 40 parts of semen cuscutae, 40 parts of cassia twig, 40 parts of hawthorn, 30 parts of medicated leaven, 30 parts of malt, 30 parts of blackberry lily, 40 parts of platycodon grandiflorum, 40 parts of radix isatidis, 40 parts of golden cypress and 30 parts of scutellaria baicalensis.
2. The preparation method of the traditional Chinese medicine composition for preventing chicken from having kidney-type infectious bronchitis before onset of labor and causing no egg laying peak, disclosed by claim 1, is characterized by comprising the following steps of:
weighing the components according to the proportion, crushing, soaking in water, decocting and extracting for multiple times, combining the extracting solutions, and concentrating to obtain the traditional Chinese medicine composition for preventing chicken from having kidney-type infectious bronchitis before laying and having no peak egg laying.
3. The preparation method of the traditional Chinese medicine composition for preventing chicken from laying no peak after suffering from nephropathogenic infectious bronchitis before childbirth according to claim 2, wherein the soaking time in water is 30min.
4. The preparation method of the traditional Chinese medicine composition for preventing chicken from laying no peak after suffering from nephropathogenic infectious bronchitis before childbirth according to claim 2, wherein the water addition amount is 3-5 times of the total mass of each component.
5. The preparation method of the traditional Chinese medicine composition for preventing chicken from suffering from kidney-type infectious bronchitis before onset of labor and having no egg laying peak after the chicken suffers from the kidney-type infectious bronchitis according to claim 2, wherein the decoction is performed for multiple times, and the process of combining the extracting solutions comprises the following steps: decocting in water for 30min, filtering to obtain first extractive solution and residue, adding water to the residue, decocting in water for 30min to obtain second extractive solution, filtering, removing residue, and mixing the first and second extractive solutions.
6. The method for preparing the traditional Chinese medicine composition for preventing chicken from laying peak after suffering from the nephropathogenic infectious bronchitis before childbirth according to claim 5, wherein the amount of the added water is 3-5 times of the total mass of the components.
7. The method of claim 2, wherein the composition is concentrated to 1.5g/ml crude drug.
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