CN105535425B - A kind of Chinese medicine composition with strengthen immunity effect and preparation method thereof and purposes - Google Patents
A kind of Chinese medicine composition with strengthen immunity effect and preparation method thereof and purposes Download PDFInfo
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Abstract
The invention belongs to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition with strengthen immunity effect and preparation method thereof and purposes.The present invention has the Chinese medicine composition of strengthen immunity effect, fully consider the channel tropism and nature and flavor of ginseng, Schisandra chinensis, Radix Ophiopogonis, fructus lycii and each Chinese medicine of Radix Salviae Miltiorrhizae, and the proportion for selecting each Chinese medicine mutual, each Chinese medicine is set to cooperate according to the compatibility relationship of " monarch, minister, help, make ", collective effect, to act on lesion, and then play the curative effect of strengthen immunity effect.Experiment shows that the Chinese medicine composition has raising effect to the serum lysozyme level of mouse, and mouse is made to have certain humidification to the external phagocytic function of macrophage, can be used as the drug of potential strengthen immunity effect.
Description
Technical field
The invention belongs to the field of Chinese medicines, and in particular to a kind of Chinese medicine composition and its preparation with strengthen immunity effect
Method and purposes.
Background technique
Modern society, many pathogenetic underlying causes of disease are that hypoimmunity or immunity are unsound.Human immunity system
It unites perfect, then body is harmonious, healthy；Otherwise body is impaired, easy infection or easily sick state are shown as.
A kind of immune specific physiological reaction for referring to body contact " antigenic foreign matter " or " dissident's ingredient ".Immune system
It is of great significance to maintenance body normal physiological function.When people's Nutrition intake insufficient (protein, vitamin, micro member
Element etc. lack) when will cause Abwehrkraft des Koepers decline, cause immunocompetence to reduce, to immunologic mechanism generate adverse effect.It is immune
System is made of immune organ, immunocyte and immune molecule.Immune organ can be divided into central immune device according to their effect
Official and peripheral immune organ；Immunocyte refers to all participation immune responses or cell related with immune response and its predecessor,
Including hematopoietic cell, lymphocyte etc..The cell for executing inherent immunity function has phagocyte, NK cell (natural killer cells)
Deng executing adaptive immunity function has T lymphocyte and bone-marrow-derived lymphocyte, and various immunocytes both originate from candidate stem cell.
The immune function of human body includes the innate immunity (nospecific immunity) and acquired immunity (specific immunity) two
Point.Specific immunity and nospecific immunity have close relationship.The former is built upon on the basis of the latter, and increases greatly
Strong the latter significantly improves body defenses function to the removing function of specific pathogen or antigenicity substance.Immune function is machine
Body gradual perfection is with evolving as a result, wherein nospecific immunity is the basis that biology is depended on for existence.
Chinese patent literature CN101612327A discloses a kind of health liquor, is made in liquor by several herbal medicine immersions
Standby to obtain, the liquor is prepared by following weight parts raw material: 48-55 parts of corn, 8-12 parts of glutinous rice, and 7-10 parts of purple rice, grain
7-10 parts, 7-10 parts of glutinous millet, 2-5 parts of barley, 2-4 parts of wheat, 0.5-2 parts of polished rice, 0.5-2 parts of sorghum, 0.5-2 parts of pea of rice；
Several Chinese medicines are made up of by weight: 4-7 parts of ginseng, 20-30 parts of gekko, and 4-7 parts of tortoise plastron, 18-22 parts of Poria cocos,
18-22 parts of RADIX POLYGONI MULTIFLORI PREPARATA, 48-52 parts of fructus lycii, 48-52 parts of RHIZOMA POLYGONATI PREPARATA, 48-52 parts of Rhizoma Gastrodiae, 7-12 parts of fructus schisandrae, raspberry
46-53 parts, 46-53 parts of Radix Salviae Miltiorrhizae, 7-12 parts of Semen Cuscutae, 47-52 parts of semen plantaginis, 47-52 parts of Chinese yam, 8-12 parts of Radix Glycyrrhizae, southern jujube 8-
12 parts, 48-53 parts of raw bark of eucommia, 18-22 parts of arillus longan, 7-12 parts of Radix Notoginseng, 7-12 parts of rhizoma atractylodis macrocephalae, Radix Ophiopogonis 18-22 part, seed of Oriental arborvitae 4-
7 parts, Semen Lablab Album 48-52 parts is fried, 27-32 parts of Fructus Crataegi, 8-12 parts of fingered citron, mulberries are 28-32 parts sub-, and 7-12 parts of Flos Chrysanthemi, sesame
7-12 parts, 48-53 parts of raisins, 48-53 parts of honey, 17-22 parts of wilsonii, 28-32 parts of sweet osmanthus；Above-mentioned several Chinese medicines when immersion
Dosage be liquor weight 15-20%.However, above-mentioned Chinese medicine composition the disadvantages of there are complicated composition, higher cost, thus
It limits its application.
Therefore, study that novel therapeutic effect is good, toxic side effect is small, composition is simple, lower-cost has enhancing immune
The drug of power effect is of great significance.
Summary of the invention
Therefore, the present invention provides the Chinese medicine group with strengthen immunity effect that a kind of therapeutic effect is good, toxic side effect is small
Object is closed, and then preparation method and purposes are provided.
In order to solve the above technical problems, the present invention is achieved through the following technical solutions:
The present invention provides a kind of Chinese medicine composition with strengthen immunity effect, the bulk pharmaceutical chemicals group of the Chinese medicine composition
Become:
Ginseng 3-9 parts by weight, Schisandra chinensis 3-9 parts by weight, Radix Ophiopogonis 6-10 parts by weight, fructus lycii 6-10 parts by weight, Radix Salviae Miltiorrhizae 6-
12 parts by weight.
Preferably, the above-mentioned Chinese medicine composition with strengthen immunity effect of the present invention, the raw material of the Chinese medicine composition
Medicine composition are as follows:
3 parts by weight of ginseng, Schisandra chinensis 6-8 parts by weight, Radix Ophiopogonis 6-7 parts by weight, fructus lycii 6-7 parts by weight, Radix Salviae Miltiorrhizae 6-7 weight
Part.
It is further preferred that the above-mentioned Chinese medicine composition with strengthen immunity effect of the present invention, the Chinese medicine composition
Bulk pharmaceutical chemicals composition are as follows:
3 parts by weight of ginseng, 6.7 parts by weight of Schisandra chinensis, 6.6 parts by weight of Radix Ophiopogonis, 6.6 parts by weight of fructus lycii, 6 weight of Radix Salviae Miltiorrhizae
Part；Or
3 parts by weight of ginseng, 8 parts by weight of Schisandra chinensis, 7 parts by weight of Radix Ophiopogonis, 7 parts by weight of fructus lycii, 7 parts by weight of Radix Salviae Miltiorrhizae；Or
3 parts by weight of ginseng, 6 parts by weight of Schisandra chinensis, 6 parts by weight of Radix Ophiopogonis, 6 parts by weight of fructus lycii, 6 parts by weight of Radix Salviae Miltiorrhizae.
The present invention also provides the preparation methods of the above-mentioned Chinese medicine composition with strengthen immunity effect, including following step
It is rapid:
(1) ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected parts by weight respectively, then add water to cook 1-3 times, every time
1-3 hours, the 8-12 times of water measured of above-mentioned raw materials medicine total weight is added every time, obtains decoction liquor A；
(2) it the Radix Ophiopogonis for taking selected parts by weight, then adds water to cook 1-3 times, it is 0.5-2 hours each, 8-12 weight is added every time
The water of amount times amount, obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give phase at 50 DEG C
The clear cream for being 1.00-1.30 to density.
Preferably, the preparation method of the above-mentioned Chinese medicine composition with strengthen immunity effect of the present invention, including following step
It is rapid:
(1) then ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected parts by weight respectively add water to cook 2 times, for the first time
The 9-11 times of water measured of above-mentioned raw materials medicine total weight is added, decocts 1.5-2.5 hours, second of addition above-mentioned raw materials medicine total weight
The 9-11 times of water measured, decoct 1-2 hours, obtain decoction liquor A；
(2) Radix Ophiopogonis of selected parts by weight is taken, is then added water to cook 2 times, it is 0.5-1.5 hours each, 9-11 is added for the first time
The water of times of weight amount, the water of second of addition 7-9 times of weight amount, obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give phase at 50 DEG C
The clear cream for being 1.05-1.20 to density.
It is further preferred that the preparation method of the above-mentioned Chinese medicine composition with strengthen immunity effect of the present invention, including
Following steps:
(1) then ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected parts by weight respectively add water to cook 2 times, for the first time
The water of 10 times of amounts of above-mentioned raw materials medicine total weight is added, decocts 2 hours, 8 times of amounts of second of addition above-mentioned raw materials medicine total weight
Water, decoct 1.5 hours, obtain decoction liquor A；
(2) Radix Ophiopogonis of selected parts by weight is taken, then adds water to cook 2 times, 1 hour every time, 10 times of weight amounts is added for the first time
Water, second is added the water of 8 times of weight amounts, obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give phase at 50 DEG C
The clear cream for being 1.10-1.15 to density.
The present invention also provides the preparation for including the above-mentioned Chinese medicine composition with strengthen immunity effect or including above-mentioned
The preparation for the Chinese medicine composition that preparation method is prepared,
The Chinese medicine composition is added customary adjuvant and clinically acceptable oral solution, particle is made according to common process
Agent, tablet, capsule, powder, pill, syrup or paste.
The customary adjuvant are as follows: filler, disintegrating agent, lubricant, suspending agent, adhesive, sweetener, corrigent, anti-corrosion
Agent, matrix etc..Filler includes: starch, pregelatinized starch, lactose, mannitol, chitin, microcrystalline cellulose, sucrose etc.；It collapses
Solving agent includes: starch, pregelatinized starch, microcrystalline cellulose, sodium carboxymethyl starch, crosslinked polyvinylpyrrolidone, low substitution hydroxyl
Third cellulose, cross-linked carboxymethyl cellulose are received；Lubricant includes: magnesium stearate, lauryl sodium sulfate, talcum powder, dioxy
SiClx etc.；Suspending agent includes: polyvinylpyrrolidone, microcrystalline cellulose, sucrose, agar, hydroxypropyl methyl cellulose etc.；Bonding
Agent includes starch slurry, polyvinylpyrrolidone, hydroxypropyl methyl cellulose etc.；Sweetener includes: saccharin sodium, aspartame, sugarcane
Sugar, honey element, enoxolone etc.；Corrigent includes: sweetener and various essence；Preservative include: parabens, benzoic acid,
Sodium benzoate, sorbic acid and its esters, benzalkonium bromide, the fixed, eucalyptus oil of acetic acid chloroethene etc.；Matrix include: PEG6000,
PEG4000, insect wax etc..
The Chinese medicine composition that is prepared the present invention also provides above-mentioned Chinese medicine composition, above-mentioned preparation method or among the above
Application of the preparation of drug composition in the drug that preparation has strengthen immunity effect.
Technical solution of the present invention has the advantages that
[ginseng] is warm-natured, flat, sweet in flavor, slight bitter；Returns spleen, lung channel, the heart channel of Hang-Shaoyin；Effect: replenish vital energy, restore pulse, and strengthen and remove vital energy, tonifying spleen benefit
Lung promotes the production of body fluid, and calms the nerves.
[Schisandra chinensis] is warm-natured, sweet in flavor, sour；Distributed in lung channel, kidney channel, the heart channel of Hang-Shaoyin；Effect: nourishing generate fluid, kidney tonifying nourishing heart, convergence are solid
It is puckery.
[Radix Ophiopogonis] cold nature is sweet in flavor, bitter；Distributed in lung channel, the heart channel of Hang-Shaoyin, stomach meridian；Effect: Yin nourishing and lung moistening, reinforcing stomach reg fluid clear away heart-fire and remove
It is tired.
[fructus lycii] property is sweet, and taste is flat；Return liver warp, kidney channel, lung channel；Effect: nourishing liver and kidney, improving eyesight, moistening lung.
[Radix Salviae Miltiorrhizae] cold nature, bitter；Thoughts of returning home warp, Liver Channel；Effect: stasis-dispelling and pain-killing, blood circulation, relieving restlessness and restlessness.
The present invention has the Chinese medicine composition of strengthen immunity effect, fully considers ginseng, Schisandra chinensis, Radix Ophiopogonis, fructus lycii
With the channel tropism and nature and flavor of each Chinese medicine of Radix Salviae Miltiorrhizae, and the proportion for selecting each Chinese medicine mutual makes each Chinese medicine according to " monarch, minister, help, make "
Compatibility relationship cooperate, collective effect, to act on lesion, and then play the curative effect of strengthen immunity effect.In addition,
It only includes five kinds of Chinese medicines that the present invention, which has the Chinese medicine composition of strengthen immunity effect, and composition is simple, cost is relatively low.
Specific embodiment
Technical solution of the present invention will be clearly and completely described below, it is clear that described embodiment is this hair
Bright a part of the embodiment, instead of all the embodiments.Based on the embodiments of the present invention, those of ordinary skill in the art are not having
Every other embodiment obtained under the premise of creative work is made, shall fall within the protection scope of the present invention.
Embodiment 1
The present embodiment has the bulk pharmaceutical chemicals composition of the Chinese medicine composition of strengthen immunity effect are as follows:
Ginseng 3g, Schisandra chinensis 6.7g, Radix Ophiopogonis 6.6g, fructus lycii 6.6g, Radix Salviae Miltiorrhizae 6g；
The preparation method of the Chinese medicine composition, comprising the following steps:
(1) then ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected weight respectively add water to cook 2 times, add for the first time
The water for entering 10 times of amounts of above-mentioned raw materials medicine total weight, decocts 2 hours, what second of 8 times that above-mentioned raw materials medicine total weight is added was measured
Water decocts 1.5 hours, obtains decoction liquor A；
(2) Radix Ophiopogonis of selected parts by weight is taken, then adds water to cook 2 times, 1 hour every time, 10 times of weight amounts is added for the first time
Water, second is added the water of 8 times of weight amounts, obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give phase at 50 DEG C
The clear cream for being 1.10-1.15 to density.
There is the present embodiment the Chinese medicine composition addition customary adjuvant of strengthen immunity effect to be made according to common process
Oral solution.
Embodiment 2
The present embodiment has the bulk pharmaceutical chemicals composition of the Chinese medicine composition of strengthen immunity effect are as follows:
Ginseng 3g, Schisandra chinensis 8g, Radix Ophiopogonis 7g, fructus lycii 7g, Radix Salviae Miltiorrhizae 7g；
The preparation method of the Chinese medicine composition, comprising the following steps:
(1) then ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected parts by weight respectively add water to cook 2 times, for the first time
The water of 9 times of amounts of above-mentioned raw materials medicine total weight is added, decocts 2.5 hours, 9 times of amounts of second of addition above-mentioned raw materials medicine total weight
Water, decoct 2 hours, obtain decoction liquor A；
(2) Radix Ophiopogonis of selected parts by weight is taken, then adds water to cook 2 times, 0.5 hour every time, 9 times of weight amounts is added for the first time
Water, second is added the water of 7 times of weight amounts, obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give phase at 50 DEG C
The clear cream for being 1.05-1.10 to density.
There is the present embodiment the Chinese medicine composition addition customary adjuvant of strengthen immunity effect to be made according to common process
Tablet.
Embodiment 3
The present embodiment has the bulk pharmaceutical chemicals composition of the Chinese medicine composition of strengthen immunity effect are as follows:
Ginseng 3g, Schisandra chinensis 6g, Radix Ophiopogonis 6g, fructus lycii 6g, Radix Salviae Miltiorrhizae 6g；
The preparation method of the Chinese medicine composition, comprising the following steps:
(1) then ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected parts by weight respectively add water to cook 2 times, for the first time
The water of 11 times of amounts of above-mentioned raw materials medicine total weight is added, decocts 1.5 hours, 11 times of second of addition above-mentioned raw materials medicine total weight
The water of amount decocts 1 hour, obtains decoction liquor A；
(2) Radix Ophiopogonis of selected parts by weight is taken, then adds water to cook 2 times, 1.5 hours every time, 11 times of weight is added for the first time
The water of amount, the water of second of 9 times of weight amount of addition, obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give phase at 50 DEG C
The clear cream for being 1.10-1.20 to density.
There is the present embodiment the Chinese medicine composition addition customary adjuvant of strengthen immunity effect to be made according to common process
Capsule.
Experimental exampleThe research of the traditional chinese medicine composition of the invention strengthen immunity effect
1, experimental material and method
(1) animal: the miscellaneous system mouse of the Rui Shi of Military Medical Science Institute's supply, half male and half female, weight 18-20g.
(2) drug: oral solution prepared by embodiment 1 is diluted with preceding with 10 times of distilled water.
(3) administration route and method: via stomach-filling, each 0.5mL, the next day it is primary, 3 times a week, administration 2-3 weeks after carry out
Detection.
2, experimental program
(1) mice serum Lysozyme Levels measurement experiment
Serum is added in micrococcus luteus bacterium solution, lysozyme dissolution of bacteria in serum causes the variation of bacterium solution light transmittance, simultaneously
Standard curve is prepared, lysozyme concentration in serum is found.After administration 2-3 weeks, mice serum is taken, its serum lysozyme is detected
Activity, observation medication influence it.Specific experiment the results are shown in Table 1.
(2) macrophages in vitro phagocytosis experiment
Turnover of Mouse Peritoneal Macrophages is taken, macrophage monolayer is made through adherency.Then it is added with the ratio of 1:100 golden yellow
Staphylococcus and3H- thymidine (3H-TDR), 37 DEG C of cultures, DNA of bacteria anabolism, incorporation3H-TDR becomes isotope mark
Remember bacterium, while bacterium is swallowed to intracellular, after 30 minutes, by a series of processing, measures intracellular isotope umber of pulse per minute
(cpm), cpm is higher, indicates that cytophagy is stronger.After administration 2-3 weeks, Turnover of Mouse Peritoneal Macrophages is obtained, with3H-
TdR incorporation methods observe the phagocytic function to staphylococcus aureus.Specific experiment the results are shown in Table 2.
3, experimental result
Influence (μ g/mL) of the table 1 to mice serum bacterium enzyme level
As shown in Table 1, the serum lysozyme level for the Oral Liquid On Mice that prepared by embodiment 1 has raising effect.
Influence of the table 2 to macrophages in vitro phagocytic function
As shown in Table 2, the oral solution that prepared by embodiment 1 makes mouse have certain increasing to the external phagocytic function of macrophage
Pretend use.
In conclusion there is the present invention Chinese medicine composition of strengthen immunity effect to have to the serum lysozyme level of mouse
Raising effect, makes mouse have certain humidification to the external phagocytic function of macrophage, can be used as potential enhancing and exempts from
The drug of epidemic disease power effect.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right
For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or
It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or
It changes still within the protection scope of the invention.
Claims (7)
1. a kind of application of Chinese medicine composition in the drug that preparation has strengthen immunity effect, which is characterized in that in described
The bulk pharmaceutical chemicals of drug composition form are as follows:
Ginseng 3-9 parts by weight, Schisandra chinensis 3-9 parts by weight, Radix Ophiopogonis 6-10 parts by weight, fructus lycii 6-10 parts by weight, Radix Salviae Miltiorrhizae 6-12 weight
Measure part.
2. application according to claim 1, which is characterized in that the bulk pharmaceutical chemicals of the Chinese medicine composition form are as follows:
3 parts by weight of ginseng, Schisandra chinensis 6-8 parts by weight, Radix Ophiopogonis 6-7 parts by weight, fructus lycii 6-7 parts by weight, Radix Salviae Miltiorrhizae 6-7 parts by weight.
3. application according to claim 2, which is characterized in that the bulk pharmaceutical chemicals of the Chinese medicine composition form are as follows:
3 parts by weight of ginseng, 6.7 parts by weight of Schisandra chinensis, 6.6 parts by weight of Radix Ophiopogonis, 6.6 parts by weight of fructus lycii, 6 parts by weight of Radix Salviae Miltiorrhizae；Or
Person
3 parts by weight of ginseng, 8 parts by weight of Schisandra chinensis, 7 parts by weight of Radix Ophiopogonis, 7 parts by weight of fructus lycii, 7 parts by weight of Radix Salviae Miltiorrhizae；Or
3 parts by weight of ginseng, 6 parts by weight of Schisandra chinensis, 6 parts by weight of Radix Ophiopogonis, 6 parts by weight of fructus lycii, 6 parts by weight of Radix Salviae Miltiorrhizae.
4. application according to claim 1, which is characterized in that the preparation method of the Chinese medicine composition includes following step
It is rapid:
(1) ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected parts by weight respectively, then add water to cook 1-3 times, and each 1-3 is small
When, the 8-12 times of water measured of above-mentioned raw materials medicine total weight is added every time, obtains decoction liquor A；
(2) it the Radix Ophiopogonis for taking selected parts by weight, then adds water to cook 1-3 times, it is 0.5-2 hours each, 8-12 times of weight is added every time
The water of amount obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give relatively close at 50 DEG C
Degree is the clear cream of 1.00-1.30.
5. application according to claim 4, which is characterized in that the preparation method of the Chinese medicine composition includes following step
It is rapid:
(1) then ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected parts by weight respectively add water to cook 2 times, be added for the first time
The 9-11 times of water measured of above-mentioned raw materials medicine total weight decocts 1.5-2.5 hours, the 9- of second of addition above-mentioned raw materials medicine total weight
The water of 11 times of amounts decocts 1-2 hours, obtains decoction liquor A；
(2) Radix Ophiopogonis of selected parts by weight is taken, is then added water to cook 2 times, it is 0.5-1.5 hours each, 9-11 weight is added for the first time
The water of amount again, the water of second of addition 8-9 times of weight amount, obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give relatively close at 50 DEG C
Degree is the clear cream of 1.05-1.20.
6. application according to claim 5, which is characterized in that the preparation method of the Chinese medicine composition includes following step
It is rapid:
(1) then ginseng, Schisandra chinensis, Radix Salviae Miltiorrhizae and the fructus lycii for taking selected parts by weight respectively add water to cook 2 times, be added for the first time
The water of 10 times of amounts of above-mentioned raw materials medicine total weight, decocts 2 hours, the water of 8 times of amounts of second of addition above-mentioned raw materials medicine total weight,
It decocts 1.5 hours, obtains decoction liquor A；
(2) Radix Ophiopogonis of selected parts by weight is taken, then adds water to cook 2 times, 1 hour every time, the water of 10 times of weight amounts is added for the first time,
The water of second of 8 times of weight amount of addition, obtains decoction liquor B；
(3) the decoction liquor A and decoction liquor B is merged, concentration staticly settles, supernatant is concentrated to give relatively close at 50 DEG C
Degree is the clear cream of 1.10-1.15.
7. application according to claim 1-6, which is characterized in that customary adjuvant is added in the Chinese medicine composition,
According to common process, clinically acceptable oral solution, granule, tablet, capsule, powder, pill, syrup or cream is made
Agent.
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| CN105497496B (en) * | 2015-12-21 | 2019-01-15 | 北京同仁堂科技发展股份有限公司 | It is a kind of with Chinese medicine composition and preparation method thereof and purposes for improving male's sexual effect |
| CN106236932A (en) * | 2016-09-28 | 2016-12-21 | 张家港威胜生物医药有限公司 | Pharmaceutical composition of a kind of enhancing immunity and preparation method thereof and purposes |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1349803A (en) * | 2000-10-20 | 2002-05-22 | 孙喆 | Medicine for treating diabetes and coronary heart disease |
| CN1872277A (en) * | 2005-06-03 | 2006-12-06 | 天津天士力制药股份有限公司 | Application of medication composition of containing magnolia vine fruit in preparing medicine for treating insufficiency of blood supply for brain |
| CN105497495A (en) * | 2015-12-21 | 2016-04-20 | 北京同仁堂科技发展股份有限公司 | Traditional Chinese medicine composition with anti-fatigue effect and preparation method and application thereof |
| CN105497496A (en) * | 2015-12-21 | 2016-04-20 | 北京同仁堂科技发展股份有限公司 | Traditional Chinese medicine composition with effect of improving male sexual functions and preparation method and application thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1349803A (en) * | 2000-10-20 | 2002-05-22 | 孙喆 | Medicine for treating diabetes and coronary heart disease |
| CN1872277A (en) * | 2005-06-03 | 2006-12-06 | 天津天士力制药股份有限公司 | Application of medication composition of containing magnolia vine fruit in preparing medicine for treating insufficiency of blood supply for brain |
| CN105497495A (en) * | 2015-12-21 | 2016-04-20 | 北京同仁堂科技发展股份有限公司 | Traditional Chinese medicine composition with anti-fatigue effect and preparation method and application thereof |
| CN105497496A (en) * | 2015-12-21 | 2016-04-20 | 北京同仁堂科技发展股份有限公司 | Traditional Chinese medicine composition with effect of improving male sexual functions and preparation method and application thereof |
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| 安神健脑液质量标准研究;古海锋等;《中国中医药信息杂志》;20100228;第17卷(第02期);50-52 |
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