CN105477148A - External-washing Zhuang medicine composition for treating infantile eczema - Google Patents
External-washing Zhuang medicine composition for treating infantile eczema Download PDFInfo
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- CN105477148A CN105477148A CN201511027019.6A CN201511027019A CN105477148A CN 105477148 A CN105477148 A CN 105477148A CN 201511027019 A CN201511027019 A CN 201511027019A CN 105477148 A CN105477148 A CN 105477148A
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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Abstract
The invention discloses an external-washing Zhuang medicine composition for treating infantile eczema. The external-washing Zhuang medicine composition is prepared from, by weight, 10-40 parts of oroxylum indicum, 10-30 parts of cardiospermum halicacabum L., 10-40 parts of radix sophorae flavescentis, 20-40 parts of oxalis comiculata, 10-30 parts of radix puerariae, 10-35 parts of purslane, 20-30 parts of golden cypress and 10-40 parts of commonwedgelet fern leaves. A preparation method of the composition includes the steps that, by weight, all types of raw material decoction piece medicine are screened and soaked with 5000 ml of cool water for one hour, 3000 ml of liquid medicine is decocted, compound slag is decocted through the same method, and decoction liquid generated through two times of decoction is combined; the dosage form is lotion. The Zhuang medicine composition has the effects of dredging main and collateral channels, clearing away damp toxin and fire toxin, clearing away heat and eliminating humidity, can obviously improve clinical symptoms of skin erythema, papule and exudation and is good medicine for treating infantile eczema.
Description
Technical field
The invention belongs to national medicine and strengthen medicine field, be specifically related to a kind of washout for the treatment of infantile eczema and strengthen drug composition.
Background technology
Eczema is infant commonly encountered diseases, is a kind of scytitis reaction caused by many factors, has and obviously ooze out tendency and the feature of pleomorphism skin lesion, clinical manifestation based on skin erythema, pimple, erosion, ooze out, to form a scab and with violent scratchiness.Skin lesion is distributed in Head And Face more, notably prolongs and trunk and extremity, often symmetrical.This cause of disease is complicated, can the acute attack because of the stimulation of various factors, and comparatively adult suffer from eczema, more easily repeatedly, protracted course of disease, if treat not in time for infantile eczema, be easy to cause secondary infection, bring unhealthy emotion to infant and the head of a family, even affect the normal development of infant.
This disease of western medical treatment is mainly symptomatic treatment or topical therapeutic, and as application antihistamine formulations, corticosteroid hormone etc., although curative effect is better, easy recurrent exerbation after drug withdrawal, be difficult to radical cure, and life-time service exists certain untoward reaction.This disease is referred to as " infantile eczema " " infantile eczma " by motherland's medical science, think its many because losing hot evil legacy in tire, drinking and eating irregularly causes dysfunction of the spleen in transportation, in accumulate damp and hot, outer evil and send out by rheumatic fever; Or wet accumulateing with the passing of time, consumption impairment of body fluid blood, raw air slaking are dry, failure of skin and muscle to be nourished and giving birth to.Strong medicine application water flowing road, damp eliminating poison, fire-toxin, expelling wind and cold, removing damp-heat, dispelling toxins and dredging collaterals.Clinical practice strengthens medicine treatment infantile eczema curative effect rapidly, and can reduce relapse rate, and side effect is little, has comparatively significant curative effect.Therefore, the object of the present invention is to provide a kind of washout for the treatment of infantile eczema to strengthen drug composition, have good clinical efficacy to infantile eczema.
Summary of the invention
The washout that the technical problem to be solved in the present invention there is provided a kind of infantile eczema strengthens drug composition.This strong drug composition has fire-through path, and damp eliminating poison, fire-toxin, dispel the wind, effect of removing damp-heat, and obviously can improve skin erythema, pimple, the clinical symptoms of oozing out, be a kind of good medicine for the treatment of infantile eczema.
The present invention solves the problems of the technologies described above by the following technical programs:
A kind of washout for the treatment of infantile eczema strengthens drug composition, its raw material, with parts by weight, comprises Semen Oroxyli 10 ~ 40 parts, triangle bubble 10 ~ 30 parts, Radix Sophorae Flavescentis 10 ~ 40 parts, Herba Oxalidis Corniculatae 20 ~ 40 parts, Radix Puerariae 10 ~ 30 parts, Herba Portulacae 10 ~ 35 parts, Cortex Phellodendri 20 ~ 30 parts, large Herba Stenolomatis Chusani 10 ~ 40 parts.
Dosage form is outer lotion.
The present invention strengthens the characteristic of each raw material included by drug composition:
Semen Oroxyli: strong by name: Cocienciengcij.Medicinal: this product is the dry mature seed of Bignoniaceae plant oroxylum indicum Oroxylumindicum (L.) Vent..Nature and flavor: bitter, sweet, cool.Effect: separate acute diseases such as cholera and sunstroke poison, heat clearing away poison, airway, anus, pain relieving.Cure mainly: exanthema subitum, pharyngalgia, cough, stomachache, carbuncle skin ulcer.
Triangle steeps: strong by name: Rumsamgakbauq.Medicinal: to be herb or the fruit of sapindaceous plant Cardiospermum halicacabum CardiospermumhalicacabumL..Nature and flavor: bitter; Pungent; Cold.Effect: clearing away heat-damp and promoting diuresis; Removing pathogenic heat from blood and toxic substance from the body.Cure mainly: jaundice; Stranguria; Eczema; Furuncle swelling toxin; Venom; Traumatic injury.
Radix Sophorae Flavescentis: strong by name: Caemhgumh.Medicinal: this product is the dry root of leguminous plant Radix Sophorae Flavescentis SophoraflavescensAit..Nature and flavor: bitter, cold.Effect: except noxious dampness, heat clearing away poison, parasite killing.Cure mainly: hematodiarrhoea, have blood in stool, jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy; External treatment trichomonal vaginitis.
Herba Oxalidis Corniculatae: strong by name: Rumsanhyezsonh, medicinal: the herb of Oxalidaceae plant Herba Oxalidis Corniculatae OxaliscorniculataL..Nature and flavor: acid, cold.Effect: heat clearing away poison, except noxious dampness, Tong Longlu, dissipating blood stasis for subsidence of swelling.Cure mainly: have loose bowels, dysentery, jaundice, gonorrhea, leucorrhea with red and white discharge, measles, spit blood, epistaxis, laryngopharynx swelling and pain, furuncle, carbuncle, scabies, haemorrhoids, proctoptosis, traumatic injury, burn.
Radix Puerariae: strong by name: Gaeugat.Medicinal: this product is the tuber of legume pueraria lobata Puerarialobata (Willd.) Ohwi..Nature and flavor: sweet, pungent, cool.Effect: dispel the wind poison, heat clearing away poison, adjusts anus, rash.Cure mainly: fever caused by exogenous pathogens headache, stiff nape and back, thirsty, quench one's thirst, measles without adequate eruption, hematodiarrhoea, has loose bowels; Hypertension neck pain.
Herba Portulacae: strong by name: Rumheu.jmax.Medicinal: to be the herb of portulacaceous plant Herba Portulacae PortulacaoleraceaL..Nature and flavor: acid, cold.Effect: clearing away heat-damp and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Cure mainly: bacillary dysentery, acute gastroenteritis, acute appendicitis, mastitis, bleeding hemorrhoids, leucorrhea; Furuncle swelling toxin is controlled in external, eczema, herpes zoster.
Cortex Phellodendri: medicinal: be the dry bark of rutaceae wampee PhellodendronchinenseSchneid. or Cortex Phellodendri PhellodendronamurenseRupr..Nature and flavor: bitter, cold.Effect: heat clearing and damp drying, pathogenic fire purging removes steams, detoxification sore treatment.Cure mainly: damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.
Large Herba Stenolomatis Chusani: strong by name: Gutnit.Medicinal: to be herb or the rhizome of Lindsaeaceae plant Folium Stenolomatis Sphenomerischinensis (L.) Ching.Nature and flavor: micro-hardship, cold, nontoxic.Effect: heat clearing away, removing toxic substances, dampness removing, hemostasis.Cure mainly: cold, fever, cough, laryngopharynx swelling and pain, enteritis, dysentery, hepatitis, damp-heat vaginal discharge, carbuncle pyogenic infections from tumour or sore, mumps, aphtha, burn and scald, poisonous snake, lyssodexis, skin eczema, haematemesis, hematuria, have blood in stool, traumatic hemorrhage.
Beneficial effect of the present invention:
Reuse Semen Oroxyli, triangle bubble, Radix Sophorae Flavescentis heat clearing away poison in side, damp eliminating poison is monarch drug altogether; Radix Puerariae, Herba Oxalidis Corniculatae, Herba Portulacae clearing away heat-damp and promoting diuresis, rash of dispeling the wind is ministerial drug altogether; Cortex Phellodendri, large Herba Stenolomatis Chusani heat-clearing and toxic substances removing, Tong Tiaolong road, fiery road are adjuvant drug.This strong drug composition has fire-through path, and damp eliminating poison, fire-toxin, dispel the wind, effect of removing damp-heat, the clinical symptoms such as obviously can improve skin erythema, pimple, ooze out, and is a kind of good medicine for the treatment of infantile eczema.
Detailed description of the invention
Below by embodiment, the invention will be further described, but not as any restriction to scope.
Embodiment 1:
The washout for the treatment of infantile eczema strengthens a drug composition, and raw material components is: Semen Oroxyli 10g, triangle bubble 10g, Radix Sophorae Flavescentis 10g, Herba Oxalidis Corniculatae 20g, Radix Puerariae 10g, Herba Portulacae 10g, Cortex Phellodendri 20g, large Herba Stenolomatis Chusani 10g.Cleaned by each raw material decoction pieces medical material respectively by weight, soak 1 hour, take medicinal liquid 3000ml with cold water 5000ml, multiple slag is decocted with method again, merges twice fried liquid.Washout, every day 1 dose, by twice fried liquid mixing, point morning and evening 2 times, each 3000ml gauze soak affected part 5 days is 1 course for the treatment of.
Clinical case:
Cui so-and-so, man, 1 years old 3 months, people from Rong County, infantile eczema 1 day, continuous external application affected part after 3 days Erythema picture recovery from illness.
Grandson so-and-so, female, 3 years old 7 months, people from Rongan County, infantile eczema 2 days, continuous external application affected part after 4 days Erythema picture recovery from illness.
Embodiment 2:
The washout for the treatment of infantile eczema strengthens a drug composition, and raw material components is: Semen Oroxyli 40g, triangle bubble 30g, Radix Sophorae Flavescentis 35g, Herba Oxalidis Corniculatae 35g, Radix Puerariae 30g, Herba Portulacae 35g, Cortex Phellodendri 30g, large Herba Stenolomatis Chusani 40g.Cleaned by each raw material decoction pieces medical material respectively by weight, soak 1 hour, take medicinal liquid 3000ml with cold water 5000ml, multiple slag is decocted with method again, merges twice fried liquid.Washout, every day 1 dose, by twice fried liquid mixing, point morning and evening 2 times, each 3000ml gauze soak affected part, 5 days 1 courses for the treatment of.
Clinical case:
Multitude so-and-so, man, 1 years old 3 months, people from Pingnan County, infantile eczema 2 days, the recovery from illness of continuous external application erythema after 3 days, pimple disease picture.
Deep so-and-so, female, 3 years old 7 months, people from Rongan County, infantile eczema 2 days, continuous external application is erythema, the recovery from illness of pimple disease picture after 4 days.
Embodiment 3:
The washout for the treatment of infantile eczema strengthens a drug composition, and raw material components is: wooden Semen Oroxyli 25g, triangle bubble 20g, Radix Sophorae Flavescentis 20g, Herba Oxalidis Corniculatae 20g, Radix Puerariae 15g, Herba Portulacae 15g, Cortex Phellodendri 20g, large Herba Stenolomatis Chusani 10g.Cleaned by each raw material decoction pieces medical material respectively by weight, soak 1 hour, take medicinal liquid 3000ml with cold water 5000ml, multiple slag is decocted with method again, merges twice fried liquid.Washout, every day 1 dose, by twice fried liquid mixing, point morning and evening 2 times, each 3000ml gauze soak affected part, 5 days 1 courses for the treatment of.
Clinical case:
Bright so-and-so, man, 2 years old 5 months, people from Shangsi County, infantile eczema 1 day, continuous external application after 4 days erythema, pimple disease picture substantially disappear.
Health so-and-so, man, 2.9 years old, people from Fusui County, infantile eczema 1 day, continuous external application after 4 days erythema, pimple disease picture substantially disappear.
Below the non-clinical statistical data that patient uses medicine of the present invention:
1 basic document
Gather hospital admission patient, draft with reference to " Chinese medical disease Standardization of diagnosis and curative effect ".Show as with bed: be 1. apt to occur in face, the fossa cubitalis, axillary fossa, extremity bend the place such as side and trunk.2. skin lesion be multiformity erythema, pimple, vesicle (not forming bulla), erosion, ooze out, incrustation etc.Lesion mild redness, obscure boundary, often symmetrical.3. the play person of itching enters group, totally 270 examples, wherein man 127 example, female 143 example, 9 ~ 96 months ages, the state of an illness 12 ~ 72 hours.
2 experiment groupings
Patient is divided into 3 groups at random, comprises treatment group 1, treatment group 2, matched group, often organize 90 examples.
3 therapeutic schemes
Treatment group 1 adopts medicine and the Therapeutic Method of embodiment 1, every day 1 dose, by twice fried liquid mixing, and point morning and evening 2 times, each 3000ml gauze soak affected part, 5 days 1 courses for the treatment of; Matched group: external Calamine Lotion, each 1 time sooner or later, each 3000ml gauze soak affected part, 5 days 1 courses for the treatment of.Treatment group and matched group are all observed 1 course for the treatment of (after recovery from illness stopping using less than 1 course for the treatment of).
4 efficacy determinations
Criterion of therapeutical effect: recovery from illness: skin and symptom disappear completely; Effective: skin turgor, sepage, flushing and pruritus obviously alleviate before all comparatively treating; Invalid: skin lesion and symptom are all without improvement.
5 statistical procedures
Adopt SPSS20.0 statistical software to analyze, enumeration data adopts X 2 test, and measurement data adopts t inspection.Be that difference has statistical significance with P<0.05.
6 experimental results
Treatment group 1 cures 70 examples, effective 14 examples, invalid 6 examples, total effective rate 93.33%; Treatment group 2 cures 67 examples, effective 15 examples, invalid 8 examples, total effective rate 91.11%; Matched group cures 60 examples, effective 14 examples, invalid 16 examples, total effective rate 82.22%.Treatment group compares with matched group, and difference has statistical significance.Treatment group clinical efficacy is better than matched group (table 1).
Table 1 matched group and treatment group Clinical efficacy comparison
Note: compare with matched group, P<0.05.
Claims (2)
1. a washout for the treatment of infantile eczema strengthens drug composition, it is characterized in that: its raw material with parts by weight, Semen Oroxyli 10 ~ 40 parts, triangle bubble 10 ~ 30 parts, Radix Sophorae Flavescentis 10 ~ 40 parts, Herba Oxalidis Corniculatae 20 ~ 40 parts, Radix Puerariae 10 ~ 30 parts, Herba Portulacae 10 ~ 35 parts, Cortex Phellodendri 20 ~ 30 parts, large Herba Stenolomatis Chusani 10 ~ 40 parts.
2. a kind of washout for the treatment of infantile eczema strengthens drug composition as claimed in claim 1, it is characterized in that: dosage form is outer lotion.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902926A (en) * | 2016-05-07 | 2016-08-31 | 庄海涛 | Traditional Chinese medicine external lotion for treating infantile eczema |
| CN109846777A (en) * | 2019-02-01 | 2019-06-07 | 上海珈凯生物科技有限公司 | It is a kind of to have effects that alleviate composition of plant extracts of baby child's eczema and preparation method thereof, application |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101780173A (en) * | 2010-03-02 | 2010-07-21 | 刘瑞兰 | Detoxifying and dampness-eliminating soup for treating infantile eczema and preparation method thereof |
| CN102973707A (en) * | 2012-11-23 | 2013-03-20 | 王恩瀚 | Drug composite for treating infantile eczema and preparation method thereof |
-
2015
- 2015-12-31 CN CN201511027019.6A patent/CN105477148A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101780173A (en) * | 2010-03-02 | 2010-07-21 | 刘瑞兰 | Detoxifying and dampness-eliminating soup for treating infantile eczema and preparation method thereof |
| CN102973707A (en) * | 2012-11-23 | 2013-03-20 | 王恩瀚 | Drug composite for treating infantile eczema and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105902926A (en) * | 2016-05-07 | 2016-08-31 | 庄海涛 | Traditional Chinese medicine external lotion for treating infantile eczema |
| CN109846777A (en) * | 2019-02-01 | 2019-06-07 | 上海珈凯生物科技有限公司 | It is a kind of to have effects that alleviate composition of plant extracts of baby child's eczema and preparation method thereof, application |
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