CN101780173A

CN101780173A - Detoxifying and dampness-eliminating soup for treating infantile eczema and preparation method thereof

Info

Publication number: CN101780173A
Application number: CN 201010143434
Authority: CN
Inventors: 刘瑞兰
Original assignee: Individual
Current assignee: Individual
Priority date: 2010-03-02
Filing date: 2010-03-02
Publication date: 2010-07-21
Anticipated expiration: 2030-03-02
Also published as: CN101780173B

Abstract

The invention discloses a detoxifying and dampness-eliminating soup for treating infantile eczema and preparation method thereof. The soup selects the following Chinese herbal medicines capable of clearing away heat and detoxifying, removing dampness and relieving itching: siberian cocklebur fruit, common cnidium fruit, densefruit pittany root-bark, lightyellow sophora root, atractylodes rhizome, amur cork-tree, belvedere fruit, purslane herb, Chinese arborvitae twig and lea and wild chrysanthemum flower. The Chinese herbal medicines are scientifically prepared by decoction. Through clinical trials, the effective rate of the curative effect reaches 99.2% for the infantile eczema caused by various factors, and the soup has no recurrence, non-toxic side effects and low treatment cost.

Description

A kind of detoxifying, removing dampness soup and preparation method for the treatment of infantile eczema

Technical field

The present invention relates to a kind of Chinese medicine composition, especially relate to a kind of Chinese medicine detoxifying, removing dampness soup for the treatment of infantile eczema.

Background technology

Infantile eczema is the common anaphylaxis dermatosis of a kind of children's, is Clinical symptoms with scalp, facial multirow skin lesion, violent pruritus, symmetrical distribution.Can betide children's's any age in period, more so with cradle.This disease has the sickness rate height, and treatment time is long, characteristics such as recurrence very easily after the treatment.The infantile eczema clinical manifestation is various, and erythra can occur in buccal, forehead, glabella and head, when serious also there is the trunk extremity.Initial stage is an erythema, is later on point shape pimple, herpes, itch very much, and the herpes breakage, transudate flows out, and does the back and forms crust.Skin lesion usually symmetry distributes.Eczema is drying type sometimes, and a small amount of canescence bran belt desquamation is promptly arranged on little pimple.Also can be the seborrhea type, ooze out faint yellow fat liquid on little maculopapule, form crust later on, with by the crown and eyebrow border, the nose, see behind the ear, but gargalesthesia is not too obvious more.The main external Western medicine of Drug therapy of present infantile eczema, general outer be coated with antiallergic and itching relieving glucocorticoids and antihistaminic such as hydrocortisone butyrate, ketotifen etc.Treatment infantile eczema Chinese medicine is fewer, and therapeutic effect is unsatisfactory.

Summary of the invention

Purpose of the present invention is exactly a problem undesirable at the therapeutic effect that exists in the infantile eczema treatment at present, that be easy to recur, and the Chinese herbal medicine science of selecting to have removing damp-heat is formulated, and therapeutic effect is good, has no side effect.

The objective of the invention is to be achieved through the following technical solutions, the detoxifying, removing dampness soup of this treatment infantile eczema is made up of the Chinese herbal medicine of following weight portion: Fructus Xanthii 10-20 part, Fructus Cnidii 15-25 part, Cortex Dictamni 15-20 part, Radix Sophorae Flavescentis 15-20 part, Rhizoma Atractylodis 7-15 part, Cortex Phellodendri 15-20 part, Fructus Kochiae 15-25 part, Herba Portulacae 10-20 part, Cacumen Platycladi 15-20 part, Flos Chrysanthemi Indici 15-25 part.

The detoxifying, removing dampness soup of this treatment infantile eczema is made up of the Chinese herbal medicine of following optimum weight part: 15 parts of Fructus Xanthii, 20 parts of Fructus Cnidiis, 17 parts of Cortex Dictamni, 17 parts of Radix Sophorae Flavescentiss, 11 parts of Rhizoma Atractylodis, 18 parts of Cortex Phellodendris, 20 parts of the Fructus Kochiae, 15 parts of Herba Portulacaes, 17 parts of Cacumen Platycladis, 20 parts of Flos Chrysanthemi Indicis.

Above crude drug is concocted separately, cleaned, dry in the air slightly to inside and outside appropriateness when suitable, section is dried, and every day, 1 dose of decocting was washed the affected part, early, middle and late respectively washing 1 time.

In technical solution of the present invention, Fructus Cnidii, Herba Portulacae, the dehumidifying of Cortex Phellodendri heat-clearing and toxic substances removing; Fructus Xanthii, Fructus Kochiae dispelling wind for relieving itching; Rhizoma Atractylodis are drying damp and strengthening spleen, expelling wind and cold; Radix Sophorae Flavescentis, Cortex Dictamni heat clearing and damp drying; Cacumen Platycladi cooling blood for hemostasis, the diffusing toxic swelling of wind-damp dispelling; The Flos Chrysanthemi Indici heat-clearing and toxic substances removing, the dispelling wind suppressing the hyperactive liver cures mainly eczematous dermatitis.

Clinical data

1, physical data

The court accepts infantile eczema 632 examples altogether for medical treatment, is divided into treatment group and matched group at random.The treatment group: in 342 examples, male 198 examples, women 144 examples.1 month-3 years old age, 4.5 months mean aves, the course of disease 1 month-8 months.110 examples that the heritability allergic constitution is arranged are to 72 examples hypersensitive of some factor in the environment, 81 examples of food anaphylaxis, agnogenic 79 examples.Matched group: matched group 290 examples, male 180 examples, women 110 examples, 1 month-3 years old age, 5.3 months mean aves, the course of disease 26 days-8 months.95 examples that the heritability allergic constitution is arranged are to 64 examples hypersensitive of some factor in the environment, 71 examples of food anaphylaxis, agnogenic 60 examples.

Two groups of patient ages, sex, state of an illness each side comparing differences do not have significance meaning (p＜0.05).

2, diagnostic criteria:

According to " disease of tcm diagnosis criterion of therapeutical effect " regulation, clinical manifestation and the lab testing person of being consistent can make a definite diagnosis.

3, efficacy assessment standard

According to " disease of tcm diagnosis criterion of therapeutical effect " regulation, clinical cure: symptom and sign complete obiteration; Take a turn for the better: cardinal symptom and sign disappear mostly, and the state of an illness is clearly better; Invalid: no change before and after symptom and the sign.

4, Therapeutic Method

In Primary Care, the treatment group: every day, 1 dose of decocting was washed the affected part, and early, middle and late each 1 time, 15 days is a course of treatment.Matched group: take ketotifen, the external hydrocortisone butyrate, 15 days is a course of treatment.Add up curative effect after two courses of treatment.

5, therapeutic effect

The treatment group: this medication therapy groups 342 examples, cure 251 examples, 88 examples that take a turn for the better, invalid 3 examples, total effective rate 99.2%.Matched group: 290 examples, cure 142 examples, take a turn for the better: 91 examples are invalid: 57 examples, total effective rate 80.3%, and relapse rate height.Treatment group curative effect obviously is better than matched group (p＜0.05).

Show the observation of curative effect of two groups of contrasts of eczema since childhood table

Two groups of statistical procedures checks as a result of infantile eczema p＜0.05, significant difference.

6, toxicity

In clinical observation 392 examples, randomly draw 261 examples and carry out liver function, kidney merit, blood routine examination, all no abnormal variation illustrates that using this medicine does not have systemic adverse reactions.

Model case:

Li Jiayi, the woman, 4 months, first visit: on October 8th, 2008 went to a doctor.Its female generation tells: it is surplus that infant women's head-ornaments etc. are located pruritus, flowing water 3 months.After the infant birth 1 month, scalp, face promptly play erythema, pimple, often scratch, rub, and scratch the sticking water knot of back stream yellow crusts, the time heavy when light, Drug therapys such as hydrocortisone butyrate, Le-Fu-Ye bacteriostatic were once used in outbreak repeatedly, curative effect does not show.Recently the skin lesion scope increases, the uneasiness of often crying and screaming, and in time, generate heat, big dry stool, red urine.Department of dermatologry is checked: the papulovesicle of the visible erythema in flakes of scalp, face, neck both sides and shirtfront skin, pimple and collection bunch, the rotten to the corn and yellow thick crust of flowing water, indefinite border.Abdomen, back, the visible pink patch of extremity skin are with a spot of pimple, phlycten and desquamation.Neck both sides and the enlargement of axillary lymph knot, 37.6 ℃ of body temperature.Be diagnosed as infantile eczema (exudative).With this detoxifying, removing dampness soup treatment 1 week back further consultation, erythra disappears substantially, adheres to two courses of treatment of medication, recovery from illness, recurrence then.

Wang Hao, the man, 8 months, anaphylaxis takes place after poliomyelitis vaccine is inoculated February in birth back, the whole body spreads all over the red rash of the millet appearance size of comparatively dense, and companion's pruritus does not just have and oozes out.The outer court is diagnosed as " acute eczema ", gives treatment such as chloromycetin, excellent Zhuo Er and Calamina weak curative effect, often recurrence. and with detoxifying, removing dampness soup treatment further consultation after 15 days, erythra disappears substantially, adheres to two courses of treatment of medication, recovery from illness, recurrence then.

The specific embodiment

Embodiment one: get Fructus Xanthii 15g, Fructus Cnidii 20g, Cortex Dictamni 17g, Radix Sophorae Flavescentis 17g, Rhizoma Atractylodis 11g, Cortex Phellodendri 18g, Fructus Kochiae 20g part, Herba Portulacae 15g, Cacumen Platycladi 17g, Flos Chrysanthemi Indici 20g concocts separately, decontamination, clean, when outer humidity was suitable within drying in the air slightly, section was dried.Add cold water 1000ml, moderate heat is boiled, changes slow fire 10 minutes, filter and remove residue, washout and soak when treating that temperature is suitable, each 20 minutes, early, middle and late each once, 15 days is a course of treatment, two courses of treatment of logotype.

Embodiment two: get Fructus Xanthii 10g, Fructus Cnidii 25g, Cortex Dictamni 15g, Radix Sophorae Flavescentis 20g, Rhizoma Atractylodis 7g, Cortex Phellodendri 20g, Fructus Kochiae 25g, Herba Portulacae 10g, Cacumen Platycladi 20g, Flos Chrysanthemi Indici 15g concoct separately, decontamination, clean, when outer humidity was suitable within drying in the air slightly, section was dried.Add cold water 950ml, moderate heat is boiled, changes slow fire 10 minutes, filter and remove residue, washout and soak when treating that temperature is suitable, each 20 minutes, early, middle and late each once, 15 days is a course of treatment, two courses of treatment of logotype.

Embodiment three: Fructus Xanthii 20g, Fructus Cnidii 15g, Cortex Dictamni 20g, Radix Sophorae Flavescentis 15g, Rhizoma Atractylodis 15g, Cortex Phellodendri part g, Fructus Kochiae 15g, Herba Portulacae 20g, Cacumen Platycladi 15g, Flos Chrysanthemi Indici 25g concoct separately, decontamination, clean, when outer humidity was suitable within drying in the air slightly, section was dried.Add cold water 1100ml, moderate heat is boiled, changes slow fire 10 minutes, filter and remove residue, washout and soak when treating that temperature is suitable, each 20 minutes, early, middle and late each once, 15 days is a course of treatment, two courses of treatment of logotype.

Claims

1. the detoxifying, removing dampness soup of treatment infantile eczema is characterized in that the detoxifying, removing dampness soup of this treatment infantile eczema is made up of the Chinese herbal medicine of following weight portion: Fructus Xanthii 10-20 part, Fructus Cnidii 15-25 part, Cortex Dictamni 15-20 part, Radix Sophorae Flavescentis 15-20 part, Rhizoma Atractylodis 7-15 part, Cortex Phellodendri 15-20 part, Fructus Kochiae 15-25 part, Herba Portulacae 10-20 part, Cacumen Platycladi 15-20 part, Flos Chrysanthemi Indici 15-25 part.

2. a kind of detoxifying, removing dampness soup for the treatment of infantile eczema according to claim 1 is characterized in that the detoxifying, removing dampness soup of this treatment infantile eczema is made up of the Chinese herbal medicine of following optimum weight part: 15 parts of Fructus Xanthii, 20 parts of Fructus Cnidiis, 17 parts of Cortex Dictamni, 17 parts of Radix Sophorae Flavescentiss, 11 parts of Rhizoma Atractylodis, 18 parts of Cortex Phellodendris, 20 parts of the Fructus Kochiae, 15 parts of Herba Portulacaes, 17 parts of Cacumen Platycladis, 20 parts of Flos Chrysanthemi Indicis.