CN105561211B - A kind of external application medical ointment for treating mammitis - Google Patents

A kind of external application medical ointment for treating mammitis Download PDF

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Publication number
CN105561211B
CN105561211B CN201610100523.2A CN201610100523A CN105561211B CN 105561211 B CN105561211 B CN 105561211B CN 201610100523 A CN201610100523 A CN 201610100523A CN 105561211 B CN105561211 B CN 105561211B
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borneol
radix
thick paste
added
medicinal powder
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CN105561211A (en
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王培智
李焱
孙宁
张俊霞
刘湘花
徐向宇
晁利芹
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Shanghai Songhao Biotechnology Co ltd
Sichuan Qianyiding Technology Co ltd
Henan University of Traditional Chinese Medicine HUTCM
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Henan University of Traditional Chinese Medicine HUTCM
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233—Bupleurum
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288—Taraxacum (dandelion)
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481—Astragalus (milkvetch)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536—Prunella or Brunella (selfheal)
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537—Salvia (sage)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A61K36/748—Oldenlandia or Hedyotis
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/89—Cyperaceae (Sedge family)
    • A61K36/8905—Cyperus (flatsedge)
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/902—Sparganiaceae (Bur-reed family)
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/15—Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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    • A61K2236/30—Extraction of the material
    • A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The present invention relates to the external application medical ointments for the treatment of mammitis, it can effectively solve conveniently, the medication problem of quick treatment mammitis, method is, by curcuma zedoary 25-35g, trigone 23-30g, olibanum 18-25g, Radix Salviae Miltiorrhizae 23-30g, dandelion 18-25g, Radix Notoginseng 18-25g, Radix Astragali 18-25g, rhizoma cyperi 28-35g, calamine 18-25g, gypsum 18-25g, radix bupleuri 13-20g, Prunella vulgaris 28-35g, oldenlandia diffusa 13-20g and borneol 8-12g are made, wherein, the above drug in addition to borneol, it is ground into medicinal powder, it mixes, the water of 6-8 times of weight of medicinal powder is added every time, it decocts 2 times, it decocts 1-1.5 hours every time, merge 2 decocting liquids, it is condensed into 50 DEG C of relative density 1.3-1.4's Then thick paste crushes borneol, be added in thick paste and mix, it is the innovation on a kind of Chinese medicine lotion for external use for treating mammitis that abundant raw material of the present invention, easily prepared production, therapeutic effect is good, quick, non-relapse after healing, and economic and social benefit is huge.

Description

A kind of external application medical ointment for treating mammitis
Technical field
The present invention relates to medicine, especially a kind of external application medical ointment for treating mammitis.
Background technique
Mammitis is the most common disease of women, refers to the pyogenic infection of mammary gland, can be divided into lactation mastitis and non- Lactation mastitis, lactation mastitis account for larger proportion, mostly acute inflammation in the morbidity of mazoitis.Non-lactation period mammary gland Inflammation, mostly chronic inflammation.Its disease incidence accounts for the first place of mammary gland disease.It includes: unmarried that clinical observation, which has morbidity in all ages and classes, Women, married unfertilized, not yet lactation and lactation women.Age also increasingly becomes younger, and is more common in 15~50 years old women.Closely The disease disease incidence shows an increasing trend year by year over a little years, and the most common suppurative mastitis often betides nursing period, especially just In 1~2 month puerpera's postpartum, therefore it is called acute nursing period or puerperium suppurative mastitis, Chinese medicine is known as " acute mastitis ".Primipara The disease incidence of acute mastitis is up to 2%~4%, 1 times more than multipara mazoitis.There are about 70%~80% women to have according to investigations Different degrees of mammitis, mammitis can cause greatly to perplex to the daily life of female friend, and serious patient is usually It is agonizing, endure torment to the fullest extent, seriously threaten the physical and mental health of women.Therefore, active treatment mammitis is necessary. There are many pharmacopoeia class for having treatment mammitis, and common treatment medication is mostly: Western medicine steroids, antibiotics, Chinese herbal medicine are oral Liquid etc., but its treatment cycle of said medicine is too long, side effect is big, cannot facilitate the defects of voluntarily using, so develop conveniently Simple and direct, Small side effects allow patient that the treatment to mammitis voluntarily may be implemented, and also can reach the therapeutic effect for the treatment of both manifestation and root cause of disease, And pharmacological property is mild, nonirritant, no dependence, without any side effects, the novel drugs for being easier to be accepted are imperative.
Summary of the invention
For above situation, for the defect for overcoming the prior art, the purpose of the present invention, which is just to provide, a kind of treats mazoitis The external application medical ointment of disease can effectively solve the problems, such as the medication of convenient, fast treatment mammitis.
The technical solution that the present invention solves is made of the material medicine of following poidometer: curcuma zedoary 25-35g, trigone 23- 30g, olibanum 18-25g, Radix Salviae Miltiorrhizae 23-30g, dandelion 18-25g, Radix Notoginseng 18-25g, Radix Astragali 18-25g, rhizoma cyperi 28-35g, furnace are sweet Stone 18-25g, gypsum 18-25g, radix bupleuri 13-20g, Prunella vulgaris 28-35g, oldenlandia diffusa 13-20g and borneol 8-12g, wherein The above drug in addition to borneol, it is ground into medicinal powder, is mixed, the water of 6-8 times of weight of medicinal powder is added every time, is decocted 2 times, is decocted every time 1-1.5 hours, merge 2 decocting liquids, be condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then crush borneol, thick paste is added Middle mixing, treatment mammitis external application medical ointment.
Abundant raw material of the present invention, easily prepared production, therapeutic effect is good, quick, non-relapse after healing, is a kind for the treatment of Innovation on the Chinese medicine lotion for external use of mammitis, economic and social benefit are huge.
Specific embodiment
It elaborates with reference to embodiments to a specific embodiment of the invention.
The present invention in specific implementation, can be provided by following embodiment.
Embodiment 1
The present invention in specific implementation, is made of the material medicine of following poidometer: curcuma zedoary 28-33g, trigone 26- 28g, olibanum 21-23g, Radix Salviae Miltiorrhizae 26-27g, dandelion 21-23g, Radix Notoginseng 21-23g, Radix Astragali 21-23g, rhizoma cyperi 31-33g, furnace are sweet Stone 21-23g, gypsum 21-23g, radix bupleuri 16-18g, Prunella vulgaris 28-33g, oldenlandia diffusa 16-18g and borneol 9-11g, wherein The above drug in addition to borneol, it is ground into medicinal powder, is mixed, the water of 6-8 times of weight of medicinal powder is added every time, is decocted 2 times, is decocted every time 1-1.5 hours, merge 2 decocting liquids, be condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then crush borneol, thick paste is added Middle mixing, treatment mammitis external application medical ointment.
Embodiment 2
The present invention in specific implementation, can also be made of the material medicine of following poidometer: curcuma zedoary 26-29g, trigone 24- 25g, olibanum 19-20g, Radix Salviae Miltiorrhizae 24-25g, dandelion 19-20g, Radix Notoginseng 19-20g, Radix Astragali 19-20g, rhizoma cyperi 29-30g, furnace are sweet Stone 19-20g, gypsum 19-20g, radix bupleuri 14-15g, Prunella vulgaris 29-30g, oldenlandia diffusa 14-15g and borneol 8.5-9.5g, In, the above drug in addition to borneol, it is ground into medicinal powder, is mixed, every time the water of addition 6-8 times of weight of medicinal powder, decoction 2 times, every time It decocts 1-1.5 hours, merges 2 decocting liquids, be condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then crush borneol, be added Mixed in thick paste, treatment mammitis external application medical ointment.
Embodiment 3
The present invention in specific implementation, can also be made of the material medicine of following poidometer: curcuma zedoary 31-34g, trigone 27- 29g, olibanum 22-24g, Radix Salviae Miltiorrhizae 27-29g, dandelion 22-24g, Radix Notoginseng 22-24g, Radix Astragali 22-24g, rhizoma cyperi 32-34g, furnace are sweet Stone 22-24g, gypsum 22-24g, radix bupleuri 17-19g, Prunella vulgaris 32-34g, oldenlandia diffusa 17-19g and borneol 10.5-11.5g, Wherein, the above drug in addition to borneol, it is ground into medicinal powder, is mixed, every time the water of addition 6-8 times of weight of medicinal powder, decoction 2 times, often Secondary decoction 1-1.5 hours merges 2 decocting liquids, is condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then crushes borneol, add Enter in thick paste and mix, treatment mammitis external application medical ointment.
Embodiment 4
The present invention in specific implementation, can also be made of the material medicine of following poidometer: curcuma zedoary 30g, trigone 26.5g, Olibanum 21.5g, Radix Salviae Miltiorrhizae 26.5g, dandelion 21.5g, Radix Notoginseng 21.5g, Radix Astragali 21.5g, rhizoma cyperi 31.5g, calamine 21.5g, stone Cream 21.5g, radix bupleuri 16.5g, Prunella vulgaris 31.5g, oldenlandia diffusa 16.5g and borneol 9.5g, wherein the above drug is removed borneol Outside, it is ground into medicinal powder, is mixed, the water of 6-8 times of weight of medicinal powder is added every time, is decocted 2 times, is decocted 1-1.5 hours every time, merges 2 Secondary decocting liquid is condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then crushes borneol, be added thick paste in mix, treatment The external application medical ointment of mammitis.
Embodiment 5
The present invention in specific implementation, can also be made of the material medicine of following poidometer: curcuma zedoary 31g, trigone 25g, cream Fragrant 20g, Radix Salviae Miltiorrhizae 25g, dandelion 20g, Radix Notoginseng 20g, Radix Astragali 20g, rhizoma cyperi 30g, calamine 20g, gypsum 20g, radix bupleuri 15g, summer Withered grass 30g, oldenlandia diffusa 15g and borneol 10g, wherein the above drug in addition to borneol, be ground into medicinal powder, mix, add every time Enter the water of 6-8 times of weight of medicinal powder, decoct 2 times, decocts 1-1.5 hours every time, merge 2 decocting liquids, be condensed into 50 DEG C of relative densities The thick paste of 1.3-1.4, then crushes borneol, be added thick paste in mix, treatment mammitis external application medical ointment.
Embodiment 6
The present invention in specific implementation, can also be made of the material medicine of following poidometer: curcuma zedoary 28g, trigone 24g, cream Fragrant 19g, Radix Salviae Miltiorrhizae 25g, dandelion 19g, Radix Notoginseng 20g, Radix Astragali 19g, rhizoma cyperi 29g, calamine 20g, gypsum 19g, radix bupleuri 15g, summer Withered grass 29g, oldenlandia diffusa 15g and borneol 9g, wherein the above drug in addition to borneol, be ground into medicinal powder, mix, add every time Enter the water of 6-8 times of weight of medicinal powder, decoct 2 times, decocts 1-1.5 hours every time, merge 2 decocting liquids, be condensed into 50 DEG C of relative densities The thick paste of 1.3-1.4, then crushes borneol, be added thick paste in mix, treatment mammitis external application medical ointment.
Embodiment 7
The present invention in specific implementation, can also be made of the material medicine of following poidometer: curcuma zedoary 33g, trigone 28g, cream Fragrant 23g, Radix Salviae Miltiorrhizae 28g, dandelion 23g, Radix Notoginseng 23g, Radix Astragali 23g, rhizoma cyperi 33g, calamine 23g, gypsum 23g, radix bupleuri 18g, summer Withered grass 33g, oldenlandia diffusa 18g and borneol 11g, wherein the above drug in addition to borneol, be ground into medicinal powder, mix, add every time Enter the water of 6-8 times of weight of medicinal powder, decoct 2 times, decocts 1-1.5 hours every time, merge 2 decocting liquids, be condensed into 50 DEG C of relative densities The thick paste of 1.3-1.4, then crushes borneol, be added thick paste in mix, treatment mammitis external application medical ointment.
In said medicine, in which:
Curcuma zedoary alias: evil mind ginger, Lan Jiang, green ginger, black ginger, Wu Jiang.Pharmacological property: pungent, bitter, temperature.Return liver, the spleen channel.Effect and work With: breaking blood and promoting the circulation of qi, clearing stagnation and killing pain.Dispelling wind and eliminating dampness, swelling and pain relieving.For rheumatalgia, intermittent headache pain, chest and hypochondrium, diarrhea pain；External application is controlled Traumatic injury, blood stasis and swelling pain.
Trigone is divided to: two class of cyperus iria L. rhizoma scirpi and rhizoma scirpi.Nature and flavor: it is bitter, it puts down.Channel tropism: enter liver, the spleen channel.Effect and effect: blood-breaking is dispelled The stasis of blood, it is approximate with curcuma zedoary, also there is rush absorption.Abdominal mass, carbuncle that chest and abdomen are swollen, amenorrhoea, postpartum stasis abdominal pain.Clinical application and cowherb Both arts are used with contract, can reinforce breaking blood and promoting the circulation of qi effect, control the accumulation of wei lump in the abdomen, irregular menstruation (amenorrhoea, dysmenorrhea) better effect.
Olibanum alias: smoked Lu Xiang, horsetail, nipple are fragrant.It processes: vinegar-fried.Nature and flavor: bitter, pungent, warm.Channel tropism: enter the heart, liver, spleen Through.Effect and effect: regulating qi and activating blood, analgesic therapy chase after poison.Promoting blood circulation and stopping pain relaxing muscles and tendons, detumescence and promoting granulation, effect qi and blood stagnation, trusted subordinate's pain Bitterly, ulcerative carbuncle pyogenic infections, sore fester, traumatic injury, dysmenorrhea, postpartum blood stasis stabbing pain.
Radix Salviae Miltiorrhizae alias: red ginseng, radix salviae miltiorrhizae, red root, root of invigorating blood circulation, red ginseng, blood join root, and flower root, RADIX SALVIAE MILTIORRHIZAE intends Radix Salviae Miltiorrhizae, Galloping horse grass, Qie cicada grass, by horse, liquor pot root, wild perillaseed root, pale reddish brown quasi- Radix Salviae Miltiorrhizae, bee sugar bowl, honey jar head, Kao Shanhong, bright red big gun, Wild ginseng etc..The pharmacological property of Radix Salviae Miltiorrhizae is bitter, slightly cold.Converge to heart and liver channels.Effect and effect: there is promoting blood circulation, nourishing blood and tranquilization, cool blood detumescence The effect of；Hemostasis head, chest, the side of body, abdomen pain are cured mainly, is gathered, irregular menstruation, dysmenorrhea menostasis, postpartum stasis abdominal pain, arthralgia, It beats the stasis of blood swell, warm disease is vexed, palpitation due to deficiency of blood, sore swollen toxin, red rash scabies.Wind-damp dispelling, degrading the channel, diuresis.For rheumatism numbness Bitterly, itch is benumbed in arthroncus.
Dandelion alias: dandelion, Pu Gongcao, sows with a drill straw in a mattress, fall forward public pod, terrible lantern, goat milk milk at Po Poding, Fu Gongying Careless, double English foretell ground, sweet vernal grass, Gu Guding, public affairs of falling forward English, true phlegm grass pharmacological property and tremble with fear, channel tropism stomach meridian, Liver Channel.Effect and effect: clear Thermal detoxification, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia.For furuncle swelling toxin, acute mastitis, scrofula, hot eyes, pharyngalgia, pulmonary abscess, acute appendicitis, jaundice with damp-heat pathogen, Puckery pain of heat gonorrhea.
Radix Notoginseng alias: pseudo-ginseng, Yunnan seven, radix notoginseng, Radix Notoginseng, mountain paint, invaluable, blood ginseng, Typhonium flagelliforme (Lodd.) Blume, field paint, ginseng three Seven；Fingered citron mountain Qi Shan paint；Radix notoginseng.Nature and flavor: warm-natured, sweet in flavor, slight bitter.Effect and effect: dissipating stasis and stanching bleeding, detumescence ding-tong.For Various inside and outside bleedings, chest and abdomen shouting pain, tumbling and swelling.(removing blood stasis and hemostasis promoting blood circulation analgesic therapy).
Radix Astragali alias: cotton stilbene, continuous stilbene, continuous Radix Astragali, cotton Radix Astragali, yellow alpine yarrow, astragalus, arrow stilbene, arrow Radix Astragali.Nature and flavor: sweet, tepor. Channel tropism: return lung, spleen, liver and kidney channel.Effect and effect: Radix Astragali has the function of invigorating qi for consolidating superficies, arrest sweating admittedly take off, torr sore myogenic, inducing diuresis for removing edema Effect.For treating deficiency of vital energy and acking in strength, the sinking of qi of middle-jiao, rush down prolapse of the anus for a long time, uterine bleeding of having blood in stool, exterior deficiency spontaneous perspiration, ulcer is difficult to burst, burst for a long time and does not holds back, blood Empty sallow, Heat Diabetes, chronic nephritis, albuminuria, diabetes etc..Astragalus root invigorating middle warmer and replenishing QI, raw solid table torr sore.
Rhizoma cyperi alias: fragrant head is careless, later green, sparrow head is fragrant, cyperi rhizoma, the rhizome of nutgrass flatsedge, Thunder God head.Nature and flavor: pungent slight bitter sweet and neutral. Nature and flavor: pungent slight bitter sweet and neutral.Effect and effect: regulating the flow of vital energy and dispeling melancholy, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, chest, the side of body, abdominal distention disappear Change bad, irregular menstruation, amenorrhea and algomenorrhea, cold hernia stomachache, swollen breasts.
Calamine alias: Gan Shi, Lu Ganshi, flacourtia rukam stone, sheep liver stone, sweet stone of swimming, furnace eyestone, drystone.Nature and flavor and channel tropism: Sweet and neutral.Return stomach meridian.Effect and effect: removing toxic substances removing nebula, the antipruritic sore of hygroscopic.For red eye, swell pain, blepharitis cililiaris, screen film The triangular mass of mucous membrane growing from the inner corner of the eye, unhealing ulcer, pus is dripping, wet sore, pruitus.
Gypsum alias: big gypsum, Yu great Shi, white tiger, ice stone, thin fibrous gypsum, microlith, soft gypsum, gypsum rubrum.Meridian distribution of property and flavor: Xin Gan trembles with fear.Stomach meridian, lung channel.Effect and effect: expelling pathogenic factors from muscles for clearing heat, relieving restlessness quench the thirst, are clearing heat and detoxicating.It controls pyreticosis high fever not move back, vexed mind Dusk, delirious speech are gone mad, thirsty and dry pharynx, and lung heat asthma is anxious, heatstroke spontaneous perspiration, stomach fire headache, toothache, and heat toxin, which is stopped up, contains, spot dermexanthesis, and dispute is raw Sore.Forge deposited myogenic sore.Ulcer sores are controlled outside, bursts and does not close up, the burning hot wound of soup.
Radix bupleuri alias: ground smokes, Asia puecon Hu, mountain dish, to eat grass, faggot bitter in taste, slightly cold.Channel tropism: liver, gallbladder channel.Effect and work With: and in inducing diaphoresis, soothing the liver, rising Yang.For cold, fever, fevers and chills alternate, distending pain in the chest and hypochondrium, irregular menstruation, uterine prolapse etc..
Prunella vulgaris alias: wooden club grass, Tie Secao, big headdress flower, summer withered head, sunset sentence, Nedong, swallow face, wheat head selfheal, Mai Xia It is withered, the iron wire summer is withered.Nature and flavor: bitter, acrid, cold.Channel tropism: gallbladder channel, Liver Channel.Effect and effect: it clears liver and improve vision；Powder detoxifcation.Argument is also Photophobia；Ophthalmalgia；Headache and dizziness；Tinnitus；Scrofula；Goiter；Acute mastitis；Mumps；Carbuncle and furuncle and pyogenic infections；Acute hepatitis, chronic hepatitis；Hypertension Disease.
Oldenlandia diffusa: alias HERBA HEDYOTIS DIFFUSAE, Herba Turczaninowiae Fastigiatae, Radix Picriae felterrae, it is bitter, light, it is cold in nature, primary efficacy be it is clearing heat and detoxicating, Medicinal powder for relieving pain knot, promoting urination and removing dampness.
Borneol: also known as piece brain, orange slices, L-Borneol, kapur, MEIHUA BINGPIAN, Dipterocarpus pilosus, plum blossom brain, borneol brain, Mei Bing It is acrid flavour, cool Deng, gas faint scent, enter the heart, Liver Channel, there is the effect of inducing resuscitation of having one's ideas straightened out, heat-clearing dissipates poison, removing nebula.
The effect of being treated to the cognition of mammitis and Chinese pharmacology to it according to Chinese medicine and pharmaceutically-active principle, Chinese medicine are recognized For this disease is more common in married woman's nursing period, is especially common with primipara.Pathogenic factor is mostly stagnation of liver qi, accumulation of stomach-heat, or The heat very obstruction of the circulation of vital energy before tire, nausea is vigorous, on rush caused by breast；Or caused by postpartum liver stomach Qi is turbid and milk condensation.It is not pregnant And swelling and pain person occurs for breast, and mostly because liver stomach is damp and hot, stagnation of liver qi, caused by accumulation of stomach-heat, therefore therapy principle are as follows: dispersing stagnated hepatoqi, broken It is raw to dredge newborn network, dispersing swelling and dissipating binds, cool blood detumescence, torr sore for blood gas, clearing stagnation and killing pain, activating microcirculation and removing stasis medicinal, clearing heat and detoxicating, dispelling wind and eliminating dampness Flesh, sore etc..The efficient combination of said medicine supports that mutually interaction reaches better therapeutic effect, has soothing the liver reason Gas, breaking blood and promoting the circulation of qi, clearing stagnation and killing pain, harmonizing the functional activities of vital QI, activating microcirculation and removing stasis medicinal, clearing heat and detoxicating, dispelling wind and eliminating dampness are dredged newborn network, dispersing swelling and dissipating binds, are supported Blood and tranquilizing mind, cool blood detumescence, torr sore myogenic, hygroscopic be antipruritic, sore and other effects, effective for treating mammitis, and through clinical real It tests and achieves satisfied effect, relevant information is as follows:
One, the standard of case is selected
Mammitis clinical manifestation are as follows:
1, breast pain: having a different characteristics in age groups, unmarried female, married unfertilized, not yet lactation women, Cardinal symptom is distending pain of the breast, often can involve bilateral simultaneously for distending pain or shouting pain, but is mostly laid particular stress on side unrelated with the menstrual cycle. Initial stage is mainly the distending pain of breast, and local Pi Wengao, tenderness the scleroma of obscure boundary occur, there is tenderness.Acute festering type cream Adenositis local skin is red, swollen, hot, pain, significantly scleroma occurs, and more, while patient may occur in which shiver with cold, height for tenderness The whole bodies void shapes such as heat, headache, inability, arteries and veins be fast.Oxter may occur in which the lymph node of enlargement at this time, there is tenderness.
2, lump in breast (abscess is formed): local skin is red, swollen, hot, pain, it will be apparent that scleroma, tenderness more, together When patient may occur in which the whole bodies void shapes such as shiver with cold, high fever, headache, inability, arteries and veins be fast.Oxter may occur in which the lymph node of enlargement at this time, There is tenderness.Abscess is formed since remedy measures are not capable or the state of an illness is further aggravated, and local organization necroses, liquefies, The focus of infection to differ in size mutually merges and forms abscess.Abscess can be single room room Xing Huoduo.The abscess of superficial is easily found, And deeper abscess fluctuation is unobvious, is not easy to find.If mazoitis patient's constitutional symptom is obvious, part and systemic drug When therapeutic effect is unobvious, it should be noted that carry out the puncture of painful area, discovery version cell comes bright in fester or smear to be extracted out The diagnosis of true abscess.
3, nipple discharge: local skin is red, swollen, hot, pain, and it is spontaneous discharge that small number of patients, which may occur in which nipple discharge, more For faint yellow, yellow green, brown, colorless slurry sample or light oyster white, also there is few person to be squeezed the visible spilling discharge of nipple.If Occur determining that inflammation uses this medicine again after hemorrhagic or coffee-like discharge needs further to check with caution.
All other diseases of exclusion simultaneously have above-mentioned inflammatory symptom person, the alternatively standard of case, and give the present invention Traditional Chinese medicinal ointment treatment.
Two, diagnostic criteria
It is all to have selection case (symptom for clinically having this sick standard), 1, patient be mostly breast feeding women, especially Be with primipara it is common, it is before unmarried or not lactation patient's frequently-occurring disease to have cracked nipple breakage history more.2, local symptom: breast is red Swollen heat pain is suppurated.Ipsilateral axillary gland can have enlargement.3, it constitutional symptom: shivers, high fever, agitation etc..4, laboratory examination: white thin Born of the same parents, which count, to be increased, and especially neutrophil leucocyte number obviously increases.Local suction can have purulent secretion when suppuration.It is diagnosed as suffering from Mammitis.
Three, therapeutic scheme
By point 6 application of traditional Chinese medicinal ointment made of prescription of the present invention (be equivalent to every time with ointment amount containing crude drug 40-60g), It is applied on double gauze, is affixed at mammary gland, change within every 3 days once, curative effect is counted after 8 times, patient requests wear movement chest during treatment Clothing, it is not possible to the pad of enlarging the bosom dressing strip support and thickening.
Four, efficacy assessment standard
Cure: symptom disappears, and physical recovery is normal, without recurrence in 3 years.
Effective: symptom has improvement or is obviously improved.
Invalid: symptom is without improvement, or even has the trend of exacerbation.
Five, statistical procedures
Clinic is treated through 158 clinical treatment observations by the above-mentioned therapeutic scheme provided, is counted and is treated after medication 8 times Effect, statistical disposition result are as follows:
143 people are cured, account for 90.5%, effective 15 people accounts for 9.5%, invalid 0 people, total effective rate 100%, that is to say, that only 158 patients having achieve different degrees of advantageous effects, and symptom has obtained different degrees of improvement, especially Cure rate is up to 90% or more, and finds no any adverse reaction in treatment, shows drug safety, curative effect is reliable and stable.
Six, typical case
Case 1
Hao, female, 25 years old, 165 centimetres of height, 110 jin of weight.Pregnant 1,1, induced abortion 0 time are produced.Existing postpartum produces nearly 1 Month, after non-lactation, often laid particular stress on side for distending pain within nearly 1 month.Nearly 20 days distending pains are obvious, generate heat with rubefaction, have and diffuse Property tubercle sense, breast throbbing pain, and have tenderness, nearly 5 days with high fever.It is just obvious afterwards with ointment 7 times (21 days) of the present invention Symptom is improved, after 21 days, no malaise symptoms (healing).It is reacted during medication without discomfort.
Case 2
It is odd certain, female, 38 years old, 163 centimetres of height, 145 jin of weight.Pregnant 3,2, induced abortion 1 time are produced.Existing 2 months postpartum, Lactation is often laid particular stress on for distending pain with side for nearly 1 month.Nearly 20 days distending pains are obvious, generate heat with rubefaction, there is diffusivity tubercle Sense, breast throbbing pain, and have tenderness, with high fever, agglomeration in nearly 3 days is gradually big, jumps pain tenderness, and swollen breasts are violent within nearly 5 days. With just significantly improving symptom behind ointment 12 times (42 days) days of the present invention, after 42 days, no malaise symptoms (healing).Nothing during medication Discomfort reaction.
Case 3
Dai, female, 18 years old, 162 centimetres of height, 98 jin of weight.It is unmarried, the asexual history of life.First menses: 5-7/28 days 14 years old, Patient's private prosecution " starts to wear the corselet of thickening for beauty, and has steel support moulding style for 18 years old." nearly 5 months swollen breasts are mostly double Side.Nipple distending pain is obvious, and breast generates heat with rubefaction, and entire breast has multiple lesser tubercles, and with tenderness.With the present invention Symptom is just significantly improved afterwards ointment 8 times (24 days), after 24 days, no malaise symptoms (healing).It is reacted during medication without discomfort.
Case 4
Journey, female, 48 years old, 167 centimetres of height, 156 jin of weight.Pregnant 4,2, induced abortion 2 times are produced.Menopause 2 years, nearly 2 Month, sore nipples are red and swollen around nipple, and it is red and swollen that entire breast is laid particular stress in left side, nipple discharge occur, be spontaneous discharge are on a small quantity light Yellow.Symptom is just significantly improved behind useful ointment of the present invention 7 times (21 days) days, after 21 days, no malaise symptoms (healing).Medication Period reacts without discomfort.
Seven, conclusion
Show that medicament composing prescription of the present invention is scientific and reasonable by above situation, have dispersing stagnated hepatoqi, breaking blood and promoting the circulation of qi, clearing stagnation and killing pain, Newborn network, dispersing swelling and dissipating binds, nourishing blood and tranquilization, cool blood detumescence, torr sore are dredged in harmonizing the functional activities of vital QI, activating microcirculation and removing stasis medicinal, clearing heat and detoxicating, dispelling wind and eliminating dampness Myogenic, hygroscopic be antipruritic, sore and other effects, and effective for treating mammitis, easy to use, cheap, therapeutic effect is good, has Efficiency is very high, and in the test of only case, cure rate is up to 90% or more, and effective percentage is up to 100%, and in the treatment without bad Reaction, shows drug safety, and curative effect is reliable and stable, is the active drug for treating mammitis, there is good clinical practice to answer It is the innovation treated on mammitis drug with value, economic and social benefit is huge.

Claims (8)

1. a kind of external application medical ointment for treating mammitis, which is characterized in that be made of the material medicine of following poidometer: curcuma zedoary 25-35g, trigone 23-30g, olibanum 18-25g, Radix Salviae Miltiorrhizae 23-30g, dandelion 18-25g, Radix Notoginseng 18-25g, Radix Astragali 18-25g, perfume (or spice) Attached 28-35g, calamine 18-25g, gypsum 18-25g, radix bupleuri 13-20g, Prunella vulgaris 28-35g, oldenlandia diffusa 13-20g and ice Piece 8-12g, wherein the above drug in addition to borneol, be ground into medicinal powder, mix, the water of 6-8 times of weight of medicinal powder is added every time, decoct It boils 2 times, decocts 1-1.5 hours every time, merge 2 decocting liquids, be condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then by ice Piece crushes, and is added in thick paste and mixes,.
2. the external application medical ointment for the treatment of mammitis according to claim 1, which is characterized in that by the raw material of following poidometer Drug is made: curcuma zedoary 28-33g, trigone 26-28g, olibanum 21-23g, Radix Salviae Miltiorrhizae 26-27g, dandelion 21-23g, Radix Notoginseng 21-23g, Radix Astragali 21-23g, rhizoma cyperi 31-33g, calamine 21-23g, gypsum 21-23g, radix bupleuri 16-18g, Prunella vulgaris 28-33g, agkistrodon Tongue grass 16-18g and borneol 9-11g, wherein the above drug in addition to borneol, be ground into medicinal powder, mix, medicinal powder 6-8 is added every time The water of times weight decocts 2 times, decocts 1-1.5 hours every time, merges 2 decocting liquids, be condensed into 50 DEG C of relative density 1.3-1.4's Then thick paste crushes borneol, be added in thick paste and mix,.
3. the external application medical ointment for the treatment of mammitis according to claim 1, which is characterized in that by the raw material of following poidometer Drug is made: curcuma zedoary 26-29g, trigone 24-25g, olibanum 19-20g, Radix Salviae Miltiorrhizae 24-25g, dandelion 19-20g, Radix Notoginseng 19-20g, Radix Astragali 19-20g, rhizoma cyperi 29-30g, calamine 19-20g, gypsum 19-20g, radix bupleuri 14-15g, Prunella vulgaris 29-30g, agkistrodon Tongue grass 14-15g and borneol 8.5-9.5g, wherein the above drug in addition to borneol, be ground into medicinal powder, mix, medicinal powder is added every time The water of 6-8 times of weight decocts 2 times, decocts 1-1.5 hours every time, merges 2 decocting liquids, be condensed into 50 DEG C of relative density 1.3-1.4 Thick paste, then borneol is crushed, be added thick paste in mix,.
4. the external application medical ointment for the treatment of mammitis according to claim 1, which is characterized in that by the raw material of following poidometer Drug is made: curcuma zedoary 31-34g, trigone 27-29g, olibanum 22-24g, Radix Salviae Miltiorrhizae 27-29g, dandelion 22-24g, Radix Notoginseng 22-24g, Radix Astragali 22-24g, rhizoma cyperi 32-34g, calamine 22-24g, gypsum 22-24g, radix bupleuri 17-19g, Prunella vulgaris 32-34g, agkistrodon Tongue grass 17-19g and borneol 10.5-11.5g, wherein the above drug in addition to borneol, be ground into medicinal powder, mix, medicine is added every time The water of 6-8 times of weight of powder decocts 2 times, decocts 1-1.5 hours every time, merges 2 decocting liquids, be condensed into 50 DEG C of relative density 1.3- 1.4 thick paste, then crushes borneol, is added in thick paste and mixes,.
5. the external application medical ointment for the treatment of mammitis according to claim 1, which is characterized in that by the raw material of following poidometer Drug is made: curcuma zedoary 30g, trigone 26.5g, olibanum 21.5g, Radix Salviae Miltiorrhizae 26.5g, dandelion 21.5g, Radix Notoginseng 21.5g, Radix Astragali 21.5g, rhizoma cyperi 31.5g, calamine 21.5g, gypsum 21.5g, radix bupleuri 16.5g, Prunella vulgaris 31.5g, oldenlandia diffusa 16.5g and Borneol 9.5g, wherein the above drug in addition to borneol, be ground into medicinal powder, mix, the water of 6-8 times of weight of medicinal powder is added every time, decoct It boils 2 times, decocts 1-1.5 hours every time, merge 2 decocting liquids, be condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then by ice Piece crushes, and is added in thick paste and mixes,.
6. the external application medical ointment for the treatment of mammitis according to claim 1, which is characterized in that by the raw material of following poidometer Drug is made: curcuma zedoary 31g, trigone 25g, olibanum 20g, Radix Salviae Miltiorrhizae 25g, dandelion 20g, Radix Notoginseng 20g, Radix Astragali 20g, rhizoma cyperi 30g, furnace Sweet stone 20g, gypsum 20g, radix bupleuri 15g, Prunella vulgaris 30g, oldenlandia diffusa 15g and borneol 10g, wherein the above drug deicing Outside piece, it is ground into medicinal powder, is mixed, the water of 6-8 times of weight of medicinal powder is added every time, is decocted 2 times, is decocted 1-1.5 hours every time, is merged 2 decocting liquids, are condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then crush borneol, are added in thick paste and mix,.
7. the external application medical ointment for the treatment of mammitis according to claim 1, which is characterized in that by the raw material of following poidometer Drug is made: curcuma zedoary 28g, trigone 24g, olibanum 19g, Radix Salviae Miltiorrhizae 25g, dandelion 19g, Radix Notoginseng 20g, Radix Astragali 19g, rhizoma cyperi 29g, furnace Sweet stone 20g, gypsum 19g, radix bupleuri 15g, Prunella vulgaris 29g, oldenlandia diffusa 15g and borneol 9g, wherein the above drug is removed borneol Outside, it is ground into medicinal powder, is mixed, the water of 6-8 times of weight of medicinal powder is added every time, is decocted 2 times, is decocted 1-1.5 hours every time, merges 2 Secondary decocting liquid is condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then crushes borneol, is added in thick paste and mixes,.
8. the external application medical ointment for the treatment of mammitis according to claim 1, which is characterized in that by the raw material of following poidometer Drug is made: curcuma zedoary 33g, trigone 28g, olibanum 23g, Radix Salviae Miltiorrhizae 28g, dandelion 23g, Radix Notoginseng 23g, Radix Astragali 23g, rhizoma cyperi 33g, furnace Sweet stone 23g, gypsum 23g, radix bupleuri 18g, Prunella vulgaris 33g, oldenlandia diffusa 18g and borneol 11g, wherein the above drug deicing Outside piece, it is ground into medicinal powder, is mixed, the water of 6-8 times of weight of medicinal powder is added every time, is decocted 2 times, is decocted 1-1.5 hours every time, is merged 2 decocting liquids, are condensed into the thick paste of 50 DEG C of relative density 1.3-1.4, then crush borneol, are added in thick paste and mix,.
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