CN110051806A - The Chinese medicinal lotion pharmaceutical formulation for treating infantile eczema - Google Patents

The Chinese medicinal lotion pharmaceutical formulation for treating infantile eczema Download PDF

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CN110051806A
CN110051806A CN201910461104.5A CN201910461104A CN110051806A CN 110051806 A CN110051806 A CN 110051806A CN 201910461104 A CN201910461104 A CN 201910461104A CN 110051806 A CN110051806 A CN 110051806A
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infantile eczema
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stemona
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马爱香
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
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    • A61K36/758Zanthoxylum, e.g. pricklyash
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention discloses a kind of formula of Chinese materia medica preparation for treating infantile eczema, are made of following components and quality proportioning: 10 ~ 15 parts of the tuber of stemona, 15 ~ 20 parts of kuh-seng, 6 ~ 12 parts of frutus cnidii, 6 ~ 15 parts of the fruit of summer cypress, 6 ~ 15 parts of cortex dictamni, 10 ~ 15 parts of Cortex Phellodendri, 6 ~ 10 parts of pericarpium zanthoxyli.Preparation method uses prior art: being impregnated 15 ~ 20 minutes after above-mentioned raw materials medicine is cleaned with cold water, then with being cooked by slow fire 15 ~ 20 minutes.It removes slag and takes juice, to cool to 30 DEG C ~ 35 DEG C or so of medical fluid, soak, washout affected part.The present invention is studied by the clinical practice of applicant's many years, is finally obtained the Chinese materia medica preparation for the treatment of infantile eczema, and the signs symptoms such as pruitus, sepage, incrustation and dry skin caused by treatment infantile eczema are effectively relieved.

Description

The Chinese medicinal lotion pharmaceutical formulation for treating infantile eczema
Technical field
The invention belongs to technical field of Chinese medicine, specially a kind of Chinese medicinal lotion pharmaceutical formulation for treating infantile eczema.
Background technique
Infantile eczema: Chinese medicine claims " infantile eczema " to be a kind of acute or subacute eczema for betiding baby's Head And Face.Less serious case face Cheek, forehead have slight erythema and a small papule, cluster or are dispersed in.Severe one can develop as large stretch of erythema, papule, papulo-vesicle.Have obvious It oozes out, scratch, most small rotten to the corn faces, surface thickness scab, entire face can be invaded and extend to incidence.
Disease incidence rises year by year the disease in recent years, not only brings great pain to patient and family members, and infant it is for oral administration, External application Western medicine compares limitation and side effect is big, and is easy recurrence.And external washout with traditional Chinese herbs had both avoided the side effect of medicine for oral administration, and curative effect Significantly, without any side effects.Therefore, how with Chinese medicine this disease is effectively treated, improves the quality of life of infant, and reduce infant father Female worry has increasingly been paid attention to the approval with society by medical field.
The Chinese medicine pathogenesis of infantile eczema mostly because lost in tire hot evil legacy or feeding desorder, the dysfunction of the spleen in transport, it is interior accumulate it is damp and hot, Exogenous disease rheumatism heat evil and cause.
Summary of the invention
Object of the present invention is to start with from clearing heat and promoting diuresis is antipruritic, with heat-clearing, dampness removing, antipruritic for fundamental law, use in treatment A kind of pure Chinese medicine external preparation of effective Chinese traditional medicine composition development, it is intended to alleviate scytitis caused by infantile eczema and exudation, The sings and symptoms such as itch, obtain good result in the course for the treatment of, cause exudation itch curative effect particularly significant eczema.
The present invention is achieved by the following technical scheme:
A kind of formula of Chinese materia medica preparation for treating infantile eczema, is made of following components and weight proportion: 10 ~ 15 parts of the tuber of stemona, kuh-seng 15 ~ 20 parts, 6 ~ 12 parts of frutus cnidii, 6 ~ 15 parts of the fruit of summer cypress, 6 ~ 15 parts of cortex dictamni, 10 ~ 15 parts of Cortex Phellodendri, 6 ~ 10 parts of pericarpium zanthoxyli.
Preparation method uses prior art: being impregnated 15 ~ 20 minutes after above-mentioned raw materials medicine is cleaned with cold water, then uses mild fire It decocts 15 ~ 20 minutes.It removes slag and takes juice, to cool to 30 DEG C ~ 35 DEG C or so of medical fluid, soak, washout affected part.
The principles of this product bulk pharmaceutical chemicals, pharmacological property and function are as follows:
The tuber of stemona: it is mild-natured, sweet in flavor, bitter, it is distributed in lung channel.Effect: moistening lung to arrest cough, delousing, desinsection.
The major functions: chronic cough, pertussis, pulmonary tuberculosis cough.External application: being made 5% decocting liquid, has strength to kill head louse, crab louse and nit Effect.
Kuh-seng: cold in nature, bitter, return heart, liver stomach, large intestine, bladder meridian.Effect: heat-clearing and damp-drying drug, desinsection be antipruritic and diuresis.It is main Control: pruitus caused by damp and hot, scabies, impetigo, leprosy and damp and hot caused jaundice, dysentery, leukorrhea, retention of damp-heat in the interior, urine are not Many damp and hot caused illnesss such as benefit.
Frutus cnidii: it is warm-natured, bitter, pungent, return kidney channel.Effect: removing dampness and destroying parasites (external application), warming kidney and enhancing yang (for oral administration).The major functions: white Band pruritus vulvae or scrotum is wet itches and sore rash, scabies, pruitus etc..It takes orally for impotence, waist and knee crymodynia, fertility etc..
Cortex dictamni: cold in nature, bitter.Effect: there are heat-clearing and damp-drying drug, removing toxic substances, antipruritic effect.The major functions: for damp and hot bleb, wet Rash, scabies symptoms include concentrated water be more or itching person.
The fruit of summer cypress: cold in nature, bitter returns bladder meridian.Effect: clearing heat and promoting diuresis, dispelling wind and arresting itching.The major functions: small caused by damp-heat in lower-JIAO Just unfavorable, leaching drips puckery pain, skin eczema, whole body itch.
Cortex Phellodendri: cold in nature, bitter returns kidney, bladder, large intestine channel.Effect: heat-clearing and damp-drying drug, purging fire for removing toxin, reducing the asthenic fever.The major functions: 1, For a variety of humidifier fevers, such as diarrhea, dysentery, leukorrhea, flaccid paralysis, jaundice.2, it is used for heat toxin bleb, eczema pruigo, it is oral administration, outer With.3, fever due to yin deficiency, hectic fever due to yin night sweat, emission are used for.
Pericarpium zanthoxyli: property heat, acrid flavour, it is slightly poisonous.Returns spleen, stomach, kidney channel.Effect: middle benefit gas, analgesic, desinsection.The major functions: being used for taste The cold of insufficiency type, coldness and pain in the epigastrium or vomiting, the caused vomiting of roundworm, abdominal pain, furthermore can be used for eczema itch again.
Above-mentioned recipe principle is described below:
The pathogenesis of infantile eczema: Chinese medicine think this disease mostly because lost in tire hot evil legacy or feeding desorder, the dysfunction of the spleen in transport, in accumulate temperature It is heat, evil by rheumatic fever outside and cause.Doctor trained in Western medicine think morbidity with mother eat albumen food, children feed improper, digestive functional disturbance with And it is sensitive etc. related to imbedibility, food-consuming structure.
Infantile eczema is to be apt to occur in a kind of acute or subacute eczema of Head And Face.Less serious case's cheek, forehead have slight erythema And small papule cluster or be dispersed in, severe one can develop as large stretch of erythema, papule, papulo-vesicle, have obviously ooze out, scratch, majority little Mi Rotten face, surface thickness scab can invade entire face and extend to incidence.
Based on clear heat with drugs of sweet flavour and cold nature removing dampness through diuresis and relieving itching, the herbal medicine of bitter cold should not be more for treatment.The party by the tuber of stemona, kuh-seng, frutus cnidii, The fruit of summer cypress, cortex dictamni, Cortex Phellodendri, pericarpium zanthoxyli composition.Tuber of stemona desinsection is antipruritic in side, and kuh-seng heat-clearing and damp-drying drug, desinsection are antipruritic, frutus cnidii eliminating dampness Desinsection is antipruritic, and kochiae fructus clears away heat and promotes diuresis, dispelling wind and arresting itching, cortex dictamni heat-clearing and damp-drying drug is antipruritic, Cortex Phellodendri heat-clearing and damp-drying drug, and pericarpium zanthoxyli desinsection is antipruritic Analgesic.The antipruritic therapeutic purposes of clearing heat and promoting diuresis are played in all medicine matchings, reach simultaneous treatment of principal and subordinate symptoms, sick self-healing.
Illustrate the reasonability and validity of prescription of the present invention below by way of clinical efficacy.
General information: treating 80 infantile eczema patients, and 80 patients come from special chinic hospital.Infant Age minimum several days 4 years old maximum, average age 2 years old, is diagnosed as this disease through outpatient service.
Treatment method: prepared by the selection tuber of stemona, kuh-seng, frutus cnidii, the fruit of summer cypress, cortex dictamni, Cortex Phellodendri, pericarpium zanthoxyli extract washes Agent, daily 1 ~ 2 soak or washout, 7 ~ 10 days as one therapeutic course count curative effect after one course for the treatment of.
Criterion of therapeutical effect:
Recovery from illness: clinical symptoms disappear, deflorescence.
Effective: clinical symptoms improve, and fash largely subsides.
Invalid: for clinical symptoms without change, deflorescence is unobvious.
Treatment results: fully recovering 60 in 80 patients, and effective 17, invalid 3, total effective rate 96%.
Typical case is as follows:
Case one: infant female, two months, Shanxi Province Xinzhou City people from Kelan County.After infant is born more than 10 days, face, neck occur red Color papule, papulo-vesicle, erythema, when symptom, go to a doctor again when light, the last week or so exacerbation of symptoms of going to a doctor, and have that fash is rubescent, has sepage, There is yellow scab, furfur in part fash.It is disappeared with sepage after our soak three days, skin lesion erythema mitigates, and continues with our soak four Fash all disappears after it.
Case two: female, 10 days one month, Shanxi Province Xinzhou City people from Kelan County.Three days or so after infant birth, face occurs Red papules, fash is dispersed in not move back always.Medical cause vaccinates the exacerbation of rear fash and erythema occurs, part fash have sepage, Crust.It is clearly better two days later with our soak, continues Schultz-Charlton after using our soak five days.
Case three: female, 15 days two months, Shanxi Province Xinzhou City people from Kelan County.Infant be born the latter moon face occur it is red Spot, papulo-vesicle, fash gradually aggravate, face red spot, yellow scab when going to a doctor, flush at neck, abdomen bone ditch.With our soak affected part five days Symptom is substantially reduced, and skin lesion flush subsides.Continue to be disappeared with three days fash symptoms.
The present invention has rational design, studies by applicant's many years clinical practice, is finally obtained in treatment infantile eczema The signs symptoms such as pruitus, sepage, incrustation and dry skin caused by treatment infantile eczema are effectively relieved in medicine preparation.
Specific embodiment
Specific implementation of the invention is described in detail below.
Embodiment 1
A kind of traditional Chinese medicine lotion formula for treating infantile eczema is made of following component and mass number proportion: 10 grams of the tuber of stemona, kuh-seng 20 Gram, 12 grams of frutus cnidii, 15 grams of the fruit of summer cypress, 10 grams of cortex dictamni, 10 grams of Cortex Phellodendri, 10 grams of pericarpium zanthoxyli.
Preparation method: it is impregnated 15 ~ 20 minutes after above-mentioned raw materials medicine is cleaned with 500 milliliters or so cold water, then uses mild fire It decocts by 20 minutes, removes slag and take 300 milliliters of juice or so.By cool to 30 degrees Celsius of medical fluid to 35 degrees centigrades, soak, washout are suffered from Place.
Treatment results: fully recovering 11 in 15 patients, and effective 4, invalid 0, total effective rate 100%.
Embodiment 2
A kind of traditional Chinese medicine lotion formula for treating infantile eczema is made of following component and mass number proportion: 12 grams of the tuber of stemona, kuh-seng 15 Gram, 10 grams of frutus cnidii, 13 grams of the fruit of summer cypress, 10 grams of cortex dictamni, 13 grams of Cortex Phellodendri, 10 grams of pericarpium zanthoxyli.
Preparation method: the preparation method is the same as that of Example 1 for above-mentioned lotion.
Treatment results: fully recovering 11 in 13 patients, and effective 2, invalid 0, total effective rate 100%.
Embodiment 3
A kind of traditional Chinese medicine lotion formula for treating infantile eczema, is made of following component and quality proportioning: 15 grams of the tuber of stemona, kuh-seng 20 Gram, 10 grams of frutus cnidii, 15 grams of the fruit of summer cypress, 10 grams of cortex dictamni, 15 grams of Cortex Phellodendri, 10 grams of pericarpium zanthoxyli.
Preparation method: the preparation method is the same as that of Example 1 for above-mentioned lotion.
Treatment results: fully recovering 10 in 13 patients, and effective 3, invalid 0, total effective rate 100%.
Embodiment 4
A kind of traditional Chinese medicine lotion formula for treating infantile eczema, is made of following component and quality proportioning: 10 grams of the tuber of stemona, kuh-seng 15 Gram, 10 grams of frutus cnidii, 10 grams of the fruit of summer cypress, 10 grams of cortex dictamni, 15 grams of Cortex Phellodendri, 10 grams of pericarpium zanthoxyli.
Preparation method: the preparation method is the same as that of Example 1 for above-mentioned lotion.
Treatment results: fully recovering 9 in 12 patients, and effective 3, invalid 0, total effective rate 100%.
Embodiment 5
A kind of traditional Chinese medicine lotion formula for treating infantile eczema, is made of following component and quality proportioning: 10 grams of the tuber of stemona, kuh-seng 20 Gram, 10 grams of frutus cnidii, 15 grams of the fruit of summer cypress, 10 grams of cortex dictamni, 15 grams of Cortex Phellodendri, 10 grams of pericarpium zanthoxyli.
Preparation method: the preparation method is the same as that of Example 1 for above-mentioned lotion.
Treatment results: fully recovering 8 in 10 patients, and effective 2, invalid 0, total effective rate 100%.
Embodiment 6
A kind of traditional Chinese medicine lotion formula for treating infantile eczema, is made of following component and quality proportioning: 10 grams of the tuber of stemona, kuh-seng 15 Gram, 6 grams of frutus cnidii, 10 grams of the fruit of summer cypress, 15 grams of cortex dictamni, 15 grams of Cortex Phellodendri, 10 grams of pericarpium zanthoxyli.
Preparation method: the preparation method is the same as that of Example 1 for above-mentioned lotion.
Treatment results: fully recovering 6 in 9 patients, and effective 2, invalid 1, total effective rate 89%.
Embodiment 7
A kind of traditional Chinese medicine lotion formula for treating infantile eczema, is made of following component and quality proportioning: 15 grams of the tuber of stemona, kuh-seng 15 Gram, 10 grams of frutus cnidii, 6 grams of the fruit of summer cypress, 6 grams of cortex dictamni, 10 grams of Cortex Phellodendri, 6 grams of pericarpium zanthoxyli.
Preparation method: the preparation method is the same as that of Example 1 for above-mentioned lotion.
Treatment results: fully recovering 5 in 8 patients, and effective 1, invalid 2, total effective rate 75%.
It should be noted last that implement case history above, only to illustrate technical solution of the present invention rather than limit.Although ginseng Example is applied according to present invention side to be described in detail, those skilled in the art should understand that.To technical solution of the present invention It modifies or equivalent replacement is without departure from the scope of technical solution of the present invention, claim of the invention should all be covered In protection scope.

Claims (2)

1. a kind of formula of Chinese materia medica preparation for treating infantile eczema, it is characterised in that: be made of following components and quality proportioning: the tuber of stemona 10 ~ 15 parts, 15 ~ 20 parts of kuh-seng, 6 ~ 12 parts of frutus cnidii, 6 ~ 15 parts of the fruit of summer cypress, 6 ~ 15 parts of cortex dictamni, 10 ~ 15 parts of Cortex Phellodendri, pericarpium zanthoxyli 6 ~ 10 parts.
2. the traditional Chinese medicine lotion formula for the treatment of infantile eczema according to claim 1, it is characterised in that: by following component and matter Number proportion is measured to form: 10 parts of the tuber of stemona, 20 parts of kuh-seng, 12 parts of frutus cnidii, 15 parts of the fruit of summer cypress, 10 parts of cortex dictamni, 10 parts of Cortex Phellodendri, pericarpium zanthoxyli 10 parts.
CN201910461104.5A 2019-05-30 2019-05-30 The Chinese medicinal lotion pharmaceutical formulation for treating infantile eczema Pending CN110051806A (en)

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CN111617204A (en) * 2020-06-23 2020-09-04 褚凡志 Itching-relieving lotion traditional Chinese medicine composition and preparation method thereof
CN112755143A (en) * 2021-03-01 2021-05-07 复旦大学附属金山医院(上海市金山区核化伤害应急救治中心、上海市金山区眼病防治所) Traditional Chinese medicine composition for treating eczema and application thereof
CN113425669A (en) * 2021-08-19 2021-09-24 陈芳英 Chinese herbal medicine bag for conditioning infantile eczema

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Publication number Priority date Publication date Assignee Title
CN111617204A (en) * 2020-06-23 2020-09-04 褚凡志 Itching-relieving lotion traditional Chinese medicine composition and preparation method thereof
CN112755143A (en) * 2021-03-01 2021-05-07 复旦大学附属金山医院(上海市金山区核化伤害应急救治中心、上海市金山区眼病防治所) Traditional Chinese medicine composition for treating eczema and application thereof
CN112755143B (en) * 2021-03-01 2022-06-24 复旦大学附属金山医院(上海市金山区核化伤害应急救治中心、上海市金山区眼病防治所) Traditional Chinese medicine composition for treating eczema and application thereof
CN113425669A (en) * 2021-08-19 2021-09-24 陈芳英 Chinese herbal medicine bag for conditioning infantile eczema

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