CN111617204A - Itching-relieving lotion traditional Chinese medicine composition and preparation method thereof - Google Patents

Itching-relieving lotion traditional Chinese medicine composition and preparation method thereof Download PDF

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CN111617204A
CN111617204A CN202010584823.9A CN202010584823A CN111617204A CN 111617204 A CN111617204 A CN 111617204A CN 202010584823 A CN202010584823 A CN 202010584823A CN 111617204 A CN111617204 A CN 111617204A
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chinese medicine
traditional chinese
medicine composition
antipruritic
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褚凡志
褚浩杰
褚浩宇
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/758Zanthoxylum, e.g. pricklyash
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/26Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268Asarum (wild ginger)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/04Antipruritics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention relates to a traditional Chinese medicine composition and a preparation technology thereof, which are used for treating allergic dermatitis, acute eczema, papular urticaria and other inflammations, in particular to an antipruritic lotion traditional Chinese medicine composition and a preparation method thereof, wherein the antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 1-3 parts of pericarpium zanthoxyli, 1-3 parts of asarum, 2-5 parts of radix sophorae flavescentis, 1-3 parts of cortex phellodendri, 1-3 parts of fructus forsythiae, 2-5 parts of radix stemonae, 2-5 parts of fructus cnidii, 2-5 parts of fructus kochiae and 1-3 parts of radix angelicae; the preparation method comprises pulverizing the Chinese medicinal materials, mixing, extracting, and refining to obtain the Chinese medicinal composition; after the antipruritic agent is used for cleaning, the antipruritic agent not only can play a role in quickly relieving itching, but also can relieve itching at the affected part and basically eliminate erythema after being used for a short time, and the antipruritic agent does not have the condition of relapse after being cured and has good curing effect.

Description

Itching-relieving lotion traditional Chinese medicine composition and preparation method thereof
Technical Field
The invention relates to a traditional Chinese medicine composition and a preparation technology thereof, which are used for treating allergic dermatitis, acute eczema, papular urticaria and other inflammations, in particular to an antipruritic lotion traditional Chinese medicine composition and a preparation method thereof.
Background
In seasons with high temperature, the probability of itching skin diseases of human bodies, such as allergic dermatitis, acute eczema, papular urticaria and other inflammations, is high, people suffering from the diseases can feel extremely uncomfortable, and the condition of splenic qi irritability can also occur, so that the emotion of the patient can be greatly influenced.
At present, after a plurality of patients suffer from the diseases, some antipruritic medicines are usually purchased for smearing, but the existing antipruritic medicines usually take temporary solution and permanent solution, some antipruritic medicines only have the effect of relieving itching, the symptoms of the patients cannot be cured, the patients need to use the medicines for a long time, and the quality of life of the patients is also affected.
Disclosure of Invention
In view of the above, the application provides an antipruritic lotion traditional Chinese medicine composition and a preparation method thereof, the antipruritic lotion traditional Chinese medicine composition is decocted by pure water to obtain a water aqua, the water aqua is used for cleaning the position with diseases, after the medicine is used for cleaning, the effect of quickly relieving itching can be achieved, the itching at the affected part can be relieved and the erythema basically subsided after the medicine is used for a short time, the relapse situation can not occur after the disease is cured, the cure effect is excellent, and the antipruritic lotion is a natural traditional Chinese medicine composition, so that the good cure effect is ensured and no side effect is caused.
The technical scheme provided by the invention is that the antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 1-3 parts of pericarpium zanthoxyli, 1-3 parts of asarum, 2-5 parts of radix sophorae flavescentis, 1-3 parts of cortex phellodendri, 1-3 parts of fructus forsythiae, 2-5 parts of radix stemonae, 2-5 parts of fructus cnidii, 2-5 parts of fructus kochiae and 1-3 parts of radix angelicae.
The antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 1.5-2.5 parts of pericarpium zanthoxyli, 1.5-2.5 parts of asarum, 3-4 parts of radix sophorae flavescentis, 1.5-2.5 parts of cortex phellodendri, 1.5-2.5 parts of fructus forsythiae, 3-4 parts of radix stemonae, 3-4 parts of fructus cnidii, 3-4 parts of fructus kochiae and 1.5-2.5 parts of radix angelicae.
The antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 2 parts of pericarpium zanthoxyli, 2 parts of asarum, 3.5 parts of radix sophorae flavescentis, 2 parts of cortex phellodendri, 2 parts of fructus forsythiae, 3.5 parts of radix stemonae, 3.5 parts of fructus cnidii, 3.5 parts of fructus kochiae and 2 parts of radix angelicae.
According to the technical scheme, the effects of drying dampness and dispelling wind, clearing heat and removing toxicity, and relieving exterior syndrome by cooling are achieved through the pharmacological action among the traditional Chinese medicine components, the dosage ratio among the components is controlled, the synergistic effect among the traditional Chinese medicine components is better, the efficacy of the prepared itching relieving lotion traditional Chinese medicine composition is better, and the itching relieving lotion traditional Chinese medicine composition has the curative effect on pruritic skin, such as pruritus, eczema, dermatitis and the like.
When the itching relieving lotion traditional Chinese medicine composition is used, a proper amount of purified water is taken to soak the medicine bag, and the medicine bag is decocted and then externally washed.
The medicinal value of each component in the application is introduced as follows:
pericarpium zanthoxyli: has effects of warming spleen and stomach, dispelling cold, eliminating dampness, relieving pain, killing parasite, removing toxic substance, relieving itching, and removing fishy smell.
Asarum: has effects in relieving exterior syndrome, dispelling cold, expelling pathogenic wind, relieving pain, inducing resuscitation, warming lung, promoting fluid retention, resisting inflammation, improving immunity, locally anesthetizing, promoting metabolism, and resisting bacteria.
Flavescent sophora root: has the effects of clearing heat and promoting diuresis, resisting bacteria and diminishing inflammation, invigorating stomach and expelling parasites, and is commonly used for treating skin itch.
Phellodendron bark: damp-heat dysentery, diarrhea, jaundice; nocturnal emission, stranguria with turbid urine, leukorrhagia; conjunctival congestion with swelling and pain; carbuncle, deep-rooted carbuncle and sore; eczema of the skin; has antibacterial and antifungal effects.
Fructus forsythiae: has in vitro antibacterial effect, and can inhibit typhoid bacillus, paratyphoid bacillus, Escherichia coli, dysentery bacillus, diphtheria bacillus, Vibrio cholerae, staphylococci, and streptococcus.
Stemona root: has effects in moistening lung qi, dispelling heat, relieving exterior syndrome, killing parasite, and killing louse.
Fructus cnidii: has the effects of clearing heat, eliminating dampness, dispelling pathogenic wind, relieving itching, removing toxic substance, relieving pain, preventing corrosion and relieving swelling.
The preparation method comprises the following steps of (1) preparing broom cypress fruit: has the effects of clearing heat, promoting diuresis, dispelling pathogenic wind and relieving itching.
Radix angelicae: has effects in relieving exterior syndrome, dispelling cold, dispelling pathogenic wind, relieving pain, dredging nasal orifice, eliminating dampness, stopping leukorrhagia, and relieving swelling and pus discharge.
The application also provides a preparation method of the itching-relieving lotion traditional Chinese medicine composition, which specifically comprises the following steps:
(1) weighing the traditional Chinese medicine components according to the proportion, selecting and removing impurities, cleaning and drying in the sun;
(2) mixing the dried traditional Chinese medicine components uniformly, and then putting the mixture into a superfine pulverizer for pulverization treatment to obtain traditional Chinese medicine powder;
(3) the Chinese medicinal composition can be obtained by extracting and refining the Chinese medicinal powder.
Further, the extraction and purification treatment method in the step (3) comprises the following steps: putting the traditional Chinese medicine powder into a container, adding an acid water solution for soaking, then fully stirring the mixture, pouring the mixture into the container capable of pressurizing and heating, adding purified water, sealing the container, increasing the pressure by compressed air, simultaneously heating, carrying out high-temperature and high-pressure extraction, cooling and releasing the pressure after extraction, then filtering out medicine residues by using a filter screen, pouring the extract into an evaporation dish for concentration, drying after concentrating to be viscous, and grinding the product into powder to obtain the traditional Chinese medicine composition for the anti-itching lotion.
Further, the pressure at the time of the high-temperature high-pressure extraction was increased to 105Kpa, and the temperature was increased to 110 ℃.
Further, the concentration temperature was 60 ℃.
Based on the explanation, compared with the prior art, the technical scheme of the application has the advantages that: (1) the antipruritic traditional Chinese medicine composition is decocted by pure water to obtain a water aqua, the water aqua is used for cleaning the position with diseases, after the medicine is used for cleaning, the effect of quickly relieving itching can be achieved, pruritus at the position with diseases can be relieved and erythema basically subsided after the medicine is used for a short time, the relapse situation can not occur after the disease is cured, the cure effect is excellent, and the antipruritic is a natural traditional Chinese medicine composition, so that the good cure effect is ensured and no side effect is caused; (2) the antipruritic traditional Chinese medicine composition has the effects of drying dampness and dispelling wind, clearing heat and removing toxicity, and relieving exterior syndrome by warming and cooling through the pharmacological action among the traditional Chinese medicine components, and simultaneously the dosage ratio among the components is controlled, so that the synergistic effect among the traditional Chinese medicine components is better, the efficacy of the prepared antipruritic lotion traditional Chinese medicine composition is better, and the antipruritic lotion traditional Chinese medicine composition has the curative effect on pruritic skin, such as pruritus, eczema, dermatitis and the like.
Detailed Description
Example 1
The antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 1 part of pericarpium zanthoxyli, 1 part of asarum, 2 parts of radix sophorae flavescentis, 1 part of cortex phellodendri, 1 part of fructus forsythiae, 2 parts of radix stemonae, 2 parts of fructus cnidii, 2 parts of fructus kochiae and 1 part of radix angelicae.
The preparation method specifically comprises the following steps:
(1) weighing the traditional Chinese medicine components according to the proportion, selecting and removing impurities, cleaning and drying in the sun;
(2) mixing the dried traditional Chinese medicine components uniformly, and then putting the mixture into a superfine pulverizer for pulverization treatment to obtain traditional Chinese medicine powder;
(3) extracting and refining the extraction mixture to obtain the antipruritic Chinese medicinal composition; the extraction and refining treatment method comprises the following steps: putting traditional Chinese medicine powder into a container, adding an acid water solution for soaking, then fully stirring the mixture, pouring the mixture into the container capable of pressurizing and heating, adding purified water, sealing the container, increasing the pressure to 105Kpa by compressed air, simultaneously heating to 110 ℃, carrying out high-temperature high-pressure extraction, cooling and releasing pressure after extraction, then filtering out medicine residues by using a filter screen, pouring the extract into an evaporation dish for concentration, wherein the concentration temperature is 60 ℃, drying after concentration to be viscous, and grinding the product into powder to obtain the antipruritic traditional Chinese medicine composition.
Example 2
The antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 3 parts of pericarpium zanthoxyli, 3 parts of asarum, 5 parts of radix sophorae flavescentis, 3 parts of cortex phellodendri, 3 parts of fructus forsythiae, 5 parts of radix stemonae, 5 parts of fructus cnidii, 5 parts of fructus kochiae and 3 parts of radix angelicae.
The preparation method specifically comprises the following steps:
(1) weighing the traditional Chinese medicine components according to the proportion, selecting and removing impurities, cleaning and drying in the sun;
(2) mixing the dried traditional Chinese medicine components uniformly, and then putting the mixture into a superfine pulverizer for pulverization treatment to obtain traditional Chinese medicine powder;
(3) extracting and refining the extraction mixture to obtain the antipruritic Chinese medicinal composition; the extraction and refining treatment method comprises the following steps: putting traditional Chinese medicine powder into a container, adding an acid water solution for soaking, then fully stirring the mixture, pouring the mixture into the container capable of pressurizing and heating, adding purified water, sealing the container, increasing the pressure to 105Kpa by compressed air, simultaneously heating to 110 ℃, carrying out high-temperature high-pressure extraction, cooling and releasing pressure after extraction, then filtering out medicine residues by using a filter screen, pouring the extract into an evaporation dish for concentration, wherein the concentration temperature is 60 ℃, drying after concentration to be viscous, and grinding the product into powder to obtain the antipruritic traditional Chinese medicine composition.
Example 3
The antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 1.5 parts of pericarpium zanthoxyli, 1.5 parts of asarum, 3 parts of radix sophorae flavescentis, 1.5 parts of cortex phellodendri, 1.5 parts of fructus forsythiae, 3 parts of radix stemonae, 3 parts of fructus cnidii, 3 parts of fructus kochiae and 1.5 parts of radix angelicae.
The preparation method specifically comprises the following steps:
(1) weighing the traditional Chinese medicine components according to the proportion, selecting and removing impurities, cleaning and drying in the sun;
(2) mixing the dried traditional Chinese medicine components uniformly, and then putting the mixture into a superfine pulverizer for pulverization treatment to obtain traditional Chinese medicine powder;
(3) extracting and refining the extraction mixture to obtain the antipruritic Chinese medicinal composition; the extraction and refining treatment method comprises the following steps: putting traditional Chinese medicine powder into a container, adding an acid water solution for soaking, then fully stirring the mixture, pouring the mixture into the container capable of pressurizing and heating, adding purified water, sealing the container, increasing the pressure to 105Kpa by compressed air, simultaneously heating to 110 ℃, carrying out high-temperature high-pressure extraction, cooling and releasing pressure after extraction, then filtering out medicine residues by using a filter screen, pouring the extract into an evaporation dish for concentration, wherein the concentration temperature is 60 ℃, drying after concentration to be viscous, and grinding the product into powder to obtain the antipruritic traditional Chinese medicine composition.
Example 4
The antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 2.5 parts of pericarpium zanthoxyli, 2.5 parts of asarum, 4 parts of radix sophorae flavescentis, 2.5 parts of cortex phellodendri, 2.5 parts of fructus forsythiae, 4 parts of radix stemonae, 4 parts of fructus cnidii, 4 parts of fructus kochiae and 2.5 parts of radix angelicae.
The preparation method specifically comprises the following steps:
(1) weighing the traditional Chinese medicine components according to the proportion, selecting and removing impurities, cleaning and drying in the sun;
(2) mixing the dried traditional Chinese medicine components uniformly, and then putting the mixture into a superfine pulverizer for pulverization treatment to obtain traditional Chinese medicine powder;
(3) extracting and refining the extraction mixture to obtain the antipruritic Chinese medicinal composition; the extraction and refining treatment method comprises the following steps: putting traditional Chinese medicine powder into a container, adding an acid water solution for soaking, then fully stirring the mixture, pouring the mixture into the container capable of pressurizing and heating, adding purified water, sealing the container, increasing the pressure to 105Kpa by compressed air, simultaneously heating to 110 ℃, carrying out high-temperature high-pressure extraction, cooling and releasing pressure after extraction, then filtering out medicine residues by using a filter screen, pouring the extract into an evaporation dish for concentration, wherein the concentration temperature is 60 ℃, drying after concentration to be viscous, and grinding the product into powder to obtain the antipruritic traditional Chinese medicine composition.
Example 5
The antipruritic lotion traditional Chinese medicine composition comprises the following components in parts by weight: 2 parts of pericarpium zanthoxyli, 2 parts of asarum, 3.5 parts of radix sophorae flavescentis, 2 parts of cortex phellodendri, 2 parts of fructus forsythiae, 3.5 parts of radix stemonae, 3.5 parts of fructus cnidii, 3.5 parts of fructus kochiae and 2 parts of radix angelicae.
The preparation method specifically comprises the following steps:
(1) weighing the traditional Chinese medicine components according to the proportion, selecting and removing impurities, cleaning and drying in the sun;
(2) mixing the dried traditional Chinese medicine components uniformly, and then putting the mixture into a superfine pulverizer for pulverization treatment to obtain traditional Chinese medicine powder;
(3) extracting and refining the extraction mixture to obtain the antipruritic Chinese medicinal composition; the extraction and refining treatment method comprises the following steps: putting traditional Chinese medicine powder into a container, adding an acid water solution for soaking, then fully stirring the mixture, pouring the mixture into the container capable of pressurizing and heating, adding purified water, sealing the container, increasing the pressure to 105Kpa by compressed air, simultaneously heating to 110 ℃, carrying out high-temperature high-pressure extraction, cooling and releasing pressure after extraction, then filtering out medicine residues by using a filter screen, pouring the extract into an evaporation dish for concentration, wherein the concentration temperature is 60 ℃, drying after concentration to be viscous, and grinding the product into powder to obtain the antipruritic traditional Chinese medicine composition.
The actual usage effect is recorded as follows:
a medical record I: the patient is Mongolian, male, 21 years old, not married, and after contacting with flowers and plants, the whole body is scattered in red plaques, slightly higher than the skin and pruritus for 2 days to come to the home for treatment;
and (3) diagnosis: allergic dermatitis;
administration of the treatment: the itching relieving lotion traditional Chinese medicine composition is used together with antihistamine medicines, and is used by insisting external washing, so that the pruritus is relieved after 2 days of use, the erythema is basically eliminated, and the pruritus and the erythema are completely eliminated and cured after five days.
Case two: the patients are born in the week, male, and 42 years old, married, self-describing painters, pruritus and desquamation of hands, erosion and exudation, and pruritus, which are not cured for more than 1 year.
And (3) diagnosis: acute eczema;
administration of the treatment: the itching relieving lotion is applied by combining the traditional Chinese medicine composition with the antihistamine medicine after the itching relieving lotion stops contacting the paint, the external application is insisted, the scabbing and itching of the erosion exudation surface are relieved after the external application is carried out for one week, the normal non-itching feeling is basically recovered after the external application is insisted for 1 month, and the feedback is consolidated and the recovery is realized after half a month of treatment.
Case three: patients who were female and female in age 11 come to the hospital for treatment after returning to the old with erythema, pimple, occasional blister and severe pruritus for 3 days;
and (3) diagnosis: papular urticaria;
administration of the treatment: the itching relieving lotion traditional Chinese medicine composition is used by continuous external washing, scabbing appears on a water bubble part after 2 days of use, the scabbing and falling off, erythema and pimple basically disappear, pruritus feel disappears after 7 days of use, and the itching relieving lotion traditional Chinese medicine composition can be cured after 10 days of use for a double-diagnosis.
The above is only a preferred embodiment of the present invention, and it should be noted that the above preferred embodiment should not be considered as limiting the present invention, and the protection scope of the present invention should be subject to the scope defined by the claims. It will be apparent to those skilled in the art that various modifications and adaptations can be made without departing from the spirit and scope of the invention, and these modifications and adaptations should be considered within the scope of the invention.

Claims (7)

1. The traditional Chinese medicine composition of the itching relieving lotion is characterized by comprising the following components in parts by weight: 1-3 parts of pericarpium zanthoxyli, 1-3 parts of asarum, 2-5 parts of radix sophorae flavescentis, 1-3 parts of cortex phellodendri, 1-3 parts of fructus forsythiae, 2-5 parts of radix stemonae, 2-5 parts of fructus cnidii, 2-5 parts of fructus kochiae and 1-3 parts of radix angelicae.
2. The antipruritic lotion traditional Chinese medicine composition according to claim 1, which comprises the following components in parts by weight: 1.5-2.5 parts of pericarpium zanthoxyli, 1.5-2.5 parts of asarum, 3-4 parts of radix sophorae flavescentis, 1.5-2.5 parts of cortex phellodendri, 1.5-2.5 parts of fructus forsythiae, 3-4 parts of radix stemonae, 3-4 parts of fructus cnidii, 3-4 parts of fructus kochiae and 1.5-2.5 parts of radix angelicae.
3. The antipruritic lotion traditional Chinese medicine composition according to claim 1, which comprises the following components in parts by weight: 2 parts of pericarpium zanthoxyli, 2 parts of asarum, 3.5 parts of radix sophorae flavescentis, 2 parts of cortex phellodendri, 2 parts of fructus forsythiae, 3.5 parts of radix stemonae, 3.5 parts of fructus cnidii, 3.5 parts of fructus kochiae and 2 parts of radix angelicae.
4. The preparation method of the itching-relieving lotion traditional Chinese medicine composition according to any one of claims 1 to 3, which is characterized by comprising the following steps:
(1) weighing the traditional Chinese medicine components according to the proportion, selecting and removing impurities, cleaning and drying in the sun;
(2) mixing the dried traditional Chinese medicine components uniformly, and then putting the mixture into a superfine pulverizer for pulverization treatment to obtain traditional Chinese medicine powder;
(3) the Chinese medicinal composition can be obtained by extracting and refining the Chinese medicinal powder.
5. The method for preparing the antipruritic lotion Chinese medicinal composition according to claim 3, wherein the extraction and refining treatment method in the step (3) comprises the following steps: putting traditional Chinese medicine powder into a container, adding an acid water solution for soaking, then fully stirring the mixture, pouring the mixture into a container capable of pressurizing and heating, adding purified water, sealing the container, increasing the pressure by compressed air, simultaneously heating, carrying out high-temperature and high-pressure extraction, cooling and releasing pressure after extraction, then filtering out dregs by a filter screen, pouring the extract into an evaporation dish for concentration, drying after concentrating to be viscous, and grinding the product into powder to obtain the traditional Chinese medicine composition for the anti-itching lotion.
6. The method for preparing antipruritic lotion according to claim 5, wherein the pressure of the high temperature and high pressure extraction is increased to 105Kpa and the temperature is increased to 110 ℃.
7. The method for preparing the antipruritic lotion Chinese medicinal composition according to claim 5, wherein the concentration temperature is 60 ℃.
CN202010584823.9A 2020-06-23 2020-06-23 Itching-relieving lotion traditional Chinese medicine composition and preparation method thereof Pending CN111617204A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104814936A (en) * 2015-04-16 2015-08-05 吴玉生 Traditional Chinese medicine extraction method
CN110051806A (en) * 2019-05-30 2019-07-26 马爱香 The Chinese medicinal lotion pharmaceutical formulation for treating infantile eczema

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104814936A (en) * 2015-04-16 2015-08-05 吴玉生 Traditional Chinese medicine extraction method
CN110051806A (en) * 2019-05-30 2019-07-26 马爱香 The Chinese medicinal lotion pharmaceutical formulation for treating infantile eczema

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Application publication date: 20200904