CN105466879B - 基于红外线(ir)定量生物分子的装置和方法 - Google Patents

基于红外线(ir)定量生物分子的装置和方法 Download PDF

Info

Publication number
CN105466879B
CN105466879B CN201510811246.1A CN201510811246A CN105466879B CN 105466879 B CN105466879 B CN 105466879B CN 201510811246 A CN201510811246 A CN 201510811246A CN 105466879 B CN105466879 B CN 105466879B
Authority
CN
China
Prior art keywords
sample
specimen holder
film
cassette
perforated membrane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN201510811246.1A
Other languages
English (en)
Chinese (zh)
Other versions
CN105466879A (zh
Inventor
E·切尔诺卡尔斯卡亚
V·乔西
P·克拉克
C·乌特札特
R·阿玛拉
T·S·里德尔
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EMD Millipore Corp
Original Assignee
Millipore Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millipore Corp filed Critical Millipore Corp
Publication of CN105466879A publication Critical patent/CN105466879A/zh
Application granted granted Critical
Publication of CN105466879B publication Critical patent/CN105466879B/zh
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J5/00—Radiation pyrometry, e.g. infrared or optical thermometry
    • G01J5/02—Constructional details
    • G01J5/0255—Sample holders for pyrometry; Cleaning of sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3563—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solids; Preparation of samples therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3577—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/359—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light using near infrared light
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
    • G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
    • G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
    • G01N21/3563—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing solids; Preparation of samples therefor
    • G01N2021/3572—Preparation of samples, e.g. salt matrices

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201510811246.1A 2011-04-14 2012-04-13 基于红外线(ir)定量生物分子的装置和方法 Expired - Fee Related CN105466879B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161475434P 2011-04-14 2011-04-14
US61/475,434 2011-04-14
CN201210110466.8A CN102901712B (zh) 2011-04-14 2012-04-13 基于红外线(ir)定量生物分子的装置和方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201210110466.8A Division CN102901712B (zh) 2011-04-14 2012-04-13 基于红外线(ir)定量生物分子的装置和方法

Publications (2)

Publication Number Publication Date
CN105466879A CN105466879A (zh) 2016-04-06
CN105466879B true CN105466879B (zh) 2019-05-17

Family

ID=45932225

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201510811246.1A Expired - Fee Related CN105466879B (zh) 2011-04-14 2012-04-13 基于红外线(ir)定量生物分子的装置和方法
CN201210110466.8A Expired - Fee Related CN102901712B (zh) 2011-04-14 2012-04-13 基于红外线(ir)定量生物分子的装置和方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201210110466.8A Expired - Fee Related CN102901712B (zh) 2011-04-14 2012-04-13 基于红外线(ir)定量生物分子的装置和方法

Country Status (11)

Country Link
US (1) US9018584B2 (enExample)
EP (1) EP2511692B1 (enExample)
JP (1) JP5723319B2 (enExample)
KR (1) KR101635802B1 (enExample)
CN (2) CN105466879B (enExample)
AU (1) AU2012202079B2 (enExample)
BR (1) BR102012008874B1 (enExample)
ES (1) ES2661322T3 (enExample)
IN (1) IN2012DE01026A (enExample)
SG (1) SG185189A1 (enExample)
WO (1) WO2012141831A1 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2968763B1 (fr) * 2010-12-08 2014-06-06 Topnir Systems Procede et dispositif de caracterisation d'un produit, procede et dispositif de detection de la transition d'un produit, procede et dispositif de determination de la composition d'un produit.
CN103852440A (zh) * 2012-12-05 2014-06-11 中国科学院大连化学物理研究所 一种傅里叶变换红外光谱测定微藻生物质组成的方法
WO2014154331A1 (en) 2013-03-28 2014-10-02 Merck Patent Gmbh Ir analysis of protein aggregates
JP6499430B2 (ja) * 2014-02-28 2019-04-10 パナソニック株式会社 鮮度情報出力方法、鮮度情報出力装置、制御プログラム
WO2016088236A1 (ja) * 2014-12-04 2016-06-09 オリンパス株式会社 液体試料の成分分析方法
CN104819954B (zh) * 2015-04-21 2018-04-17 曾安 免标记物近红外检测样品中生物物质含量的方法
JP6568796B2 (ja) * 2015-05-26 2019-08-28 花王株式会社 角層の保湿状態の評価方法
JP6974810B2 (ja) * 2016-08-25 2021-12-01 株式会社東レリサーチセンター マイクロ分光分析用試料台の作製方法
WO2019070957A1 (en) 2017-10-06 2019-04-11 Bio-Rad Laboratories, Inc. Protein quantitation device
CN113167717B (zh) * 2018-11-26 2024-08-06 国立研究开发法人物质材料研究机构 液体试样分析方法和装置
CN109932354B (zh) * 2019-05-06 2021-10-08 中山大学 一种用于表面增强拉曼光谱痕量分析的原位分离富集装置及应用
CN111471589A (zh) * 2020-04-23 2020-07-31 华中科技大学 一种红外定量pcr核酸检测装置
CN116448709A (zh) * 2023-04-07 2023-07-18 上海佑尼化学有限公司 一种检测清洗剂工作液中非离子乳化剂的方法及其应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605838A (en) * 1993-09-17 1997-02-25 Boehringer Mannheim Gmbh Method for the quantitative analysis of sample liquid
US5764355A (en) * 1996-01-12 1998-06-09 Gagnon; David R. Spectroscopic sample holder
US5958345A (en) * 1997-03-14 1999-09-28 Moxtek, Inc. Thin film sample support
CN101883865A (zh) * 2007-09-18 2010-11-10 普里莫里根生物科技有限责任公司 无框多重微阵列

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6182806A (ja) 1984-09-28 1986-04-26 Sumitomo Electric Ind Ltd 液体膜
JPS61152700A (ja) * 1984-12-26 1986-07-11 Susumu Kogyo Kk タンパク質固定用膜担体およびその製造法
US4618475A (en) 1985-08-30 1986-10-21 Miles Laboratories, Inc. Reagent test device containing hydrophobic barriers
CA1337682C (en) * 1988-04-28 1995-12-05 Roger Phillips Whole blood glucose test strip
US5443727A (en) * 1990-10-30 1995-08-22 Minnesota Mining And Manufacturing Company Articles having a polymeric shell and method for preparing same
US5470757A (en) 1991-06-25 1995-11-28 Minnesota Mining And Manufacturing Company Spectroscopic sample holder and method for using same
EP0591417B1 (en) * 1991-06-25 1998-08-05 Minnesota Mining And Manufacturing Company Spectroscopic sample holder and method for using same
US5458852A (en) * 1992-05-21 1995-10-17 Biosite Diagnostics, Inc. Diagnostic devices for the controlled movement of reagents without membranes
EP0644412A3 (de) * 1993-09-17 1995-08-09 Boehringer Mannheim Gmbh Verfahren zur Analyse klinisch relevanter Flüssigkeiten und Suspensionen.
DE19509094A1 (de) 1995-03-16 1996-09-26 Boehringer Mannheim Gmbh Quantitative Transmissionsspektroskopie unter Verwendung von Probenträgern mit Netzen
DE19754978C2 (de) 1997-12-11 2000-07-13 Bruker Daltonik Gmbh Probenträger für die MALDI-Massenspektrometrie nebst Verfahren zur Herstellung der Platten und zum Aufbringen der Proben
US6893877B2 (en) * 1998-01-12 2005-05-17 Massachusetts Institute Of Technology Methods for screening substances in a microwell array
JP2002267667A (ja) 2001-03-08 2002-09-18 Hitachi Software Eng Co Ltd マイクロアレイ及びマイクロアレイ用基板
JP2002372492A (ja) * 2001-06-14 2002-12-26 Nippon Steel Corp 油中の水分定量方法
JP2004534226A (ja) 2001-06-29 2004-11-11 メソ スケイル テクノロジーズ,エルエルシー 発光試験測定用のアッセイプレート、リーダシステム及び方法
US6983177B2 (en) 2003-01-06 2006-01-03 Optiscan Biomedical Corporation Layered spectroscopic sample element with microporous membrane
JP4719891B2 (ja) 2004-07-30 2011-07-06 国立大学法人 千葉大学 赤外分光法を用いた血液中のグルコース濃度を測定する方法及びそれを用いた装置
CN100565186C (zh) 2006-01-26 2009-12-02 南京师范大学 药物与环糊精的相互作用及其药学性能的拉曼光谱分析方法
US8263360B2 (en) * 2006-01-30 2012-09-11 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Hydrophilic IR transparent membrane, spectroscopic sample holder comprising same and method of using same
WO2009058867A2 (en) 2007-10-29 2009-05-07 Primorigen Biosciences, Llc Affinity measurements using frameless multiplexed microarrays
JP4994318B2 (ja) * 2008-06-26 2012-08-08 株式会社フジクラ 浸水センサ
JP2010008290A (ja) * 2008-06-27 2010-01-14 Tohoku Univ 生体高分子測定用メンブレンの製造方法および生体高分子またはその相互作用の測定方法
US8546752B2 (en) * 2009-12-07 2013-10-01 Advion Inc. Solid-phase extraction (SPE) tips and methods of use
DE102010054581A1 (de) * 2010-12-15 2012-06-21 Bruker Daltonik Gmbh Probenpräparation für die Ionisierung mit matrixunterstützter Laserdesorption

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5605838A (en) * 1993-09-17 1997-02-25 Boehringer Mannheim Gmbh Method for the quantitative analysis of sample liquid
US5764355A (en) * 1996-01-12 1998-06-09 Gagnon; David R. Spectroscopic sample holder
US5958345A (en) * 1997-03-14 1999-09-28 Moxtek, Inc. Thin film sample support
CN101883865A (zh) * 2007-09-18 2010-11-10 普里莫里根生物科技有限责任公司 无框多重微阵列

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Paper Microzone Plates;Emanuel Carrilho等;《Analytical Chemistry》;20091231;全文

Also Published As

Publication number Publication date
BR102012008874A2 (pt) 2014-05-13
JP2012225910A (ja) 2012-11-15
CN102901712A (zh) 2013-01-30
AU2012202079A1 (en) 2012-11-01
EP2511692A2 (en) 2012-10-17
CN102901712B (zh) 2016-10-12
AU2012202079B2 (en) 2013-10-17
IN2012DE01026A (enExample) 2015-07-24
KR20120117642A (ko) 2012-10-24
SG185189A1 (en) 2012-11-29
EP2511692A3 (en) 2013-11-06
EP2511692B1 (en) 2018-02-14
WO2012141831A9 (en) 2013-08-15
KR101635802B1 (ko) 2016-07-04
JP5723319B2 (ja) 2015-05-27
BR102012008874B1 (pt) 2020-01-21
ES2661322T3 (es) 2018-03-28
WO2012141831A1 (en) 2012-10-18
CN105466879A (zh) 2016-04-06
US9018584B2 (en) 2015-04-28
US20130062523A1 (en) 2013-03-14

Similar Documents

Publication Publication Date Title
KR101635802B1 (ko) 생체분자를 적외선(ir)계 정량하기 위한 장치 및 방법
Sabbatini et al. Infrared spectroscopy as a new tool for studying single living cells: is there a niche?
Yaseen et al. Detection of omethoate residues in peach with surface-enhanced Raman spectroscopy
Yang et al. Terahertz spectroscopy for bacterial detection: opportunities and challenges
Herrera-Chacon et al. Bioelectronic tongue using MIP sensors for the resolution of volatile phenolic compounds
Salman et al. FTIR spectroscopic method for detection of cells infected with herpes viruses
Sundaram et al. Detection and differentiation of Salmonella serotypes using surface enhanced Raman scattering (SERS) technique
Nimesh et al. Current status and future perspectives of mass spectrometry imaging
Tian et al. Surface-Enhanced raman analysis of uric acid and hypoxanthine analysis in fractionated bodily fluids
Song et al. In situ hydrogel conditioning of tissue samples to enhance the drug’s sensitivity in ambient mass spectrometry imaging
Portaccio et al. FT-IR microscopy characterization of sol–gel layers prior and after glucose oxidase immobilization for biosensing applications
Musmann et al. Spectroscopic methods and their applicability for high‐throughput characterization of mammalian cell cultures in automated cell culture systems
Serita et al. I-design terahertz microfluidic chip for attomole-level sensing
Zhao et al. Comprehensive SERS–LFIA Platform for Ultrasensitive Detection and Automated Discrimination of Chloramphenicol Residues in Aquatic Products
Tian et al. Strategy to enhance the wettability of bioacive paper-based sensors
Czaja et al. Assessment of unmixing approaches for the quantitation of SERS nanoparticles in highly multiplexed spectral images
KR102738886B1 (ko) 완전 비표지자 바이오 센서 및 그 센서를 사용하는 테라헤르쯔 시간 기반 분광 장치
Bilal et al. Raman spectroscopy based discrimination of NS1 positive and negative dengue virus infected serum
EP2299259A1 (en) Method and Apparatus for In-Vitro-Analysis of Biological Cells and/or Microorganisms
Globus et al. Biological detection with terahertz spectroscopy
Erukhimovitch et al. Identification of contaminated cells with viruses, bacteria, or fungi by Fourier transform infrared microspectroscopy
Ventrella et al. Biomaterials based on photosynthetic membranes as potential sensors for herbicides
US8552383B2 (en) Methods and systems for in-vitro analysis of biological cells and/or microorganisms
Souli et al. Applying broadband dielectric spectroscopy (BDS) for the biophysical characterization of mammalian tissues under a variety of cellular stresses
Vajpayee et al. Food forensics: Fundamentals and technical advancements

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20190517

CF01 Termination of patent right due to non-payment of annual fee