CN105457118B - Apparatus for purifying blood and system - Google Patents
Apparatus for purifying blood and system Download PDFInfo
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- CN105457118B CN105457118B CN201510956641.9A CN201510956641A CN105457118B CN 105457118 B CN105457118 B CN 105457118B CN 201510956641 A CN201510956641 A CN 201510956641A CN 105457118 B CN105457118 B CN 105457118B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
- A61M1/1627—Dialyser of the inside perfusion type, i.e. blood flow inside hollow membrane fibres or tubes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3687—Chemical treatment
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- Heart & Thoracic Surgery (AREA)
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- Animal Behavior & Ethology (AREA)
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- Urology & Nephrology (AREA)
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- Chemical & Material Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
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Abstract
The blood purification system built the invention provides a kind of apparatus for purifying blood and with the apparatus for purifying blood, belongs to medical instruments field.Wherein, apparatus for purifying blood includes perfusion unit, unit with dialysis, connection unit and control unit.Perfusion unit includes perfusion chamber, and the import of perfusion chamber is the artery port of apparatus for purifying blood.Unit with dialysis includes dialysis chamber, and the outlet of dialysis chamber is the vein port of apparatus for purifying blood.Connection unit includes shell and dividing plate, and the chamber that dividing plate surrounds shell is separated into separate first chamber and second chamber, and first chamber is perfusion chamber, and second chamber is dialysis chamber.Shell is provided with dialyzate import in the side-walls of dialysis chamber and dialyzate exports.Control unit includes controlling switch and outer even port, and controlling switch is used to selectively connect the two in the outlet of perfusion chamber, the import of dialysis chamber and outer connectivity port.Improve the security and the convenience of operation of blood purification treatment.
Description
Technical field
The present invention relates to medical instruments field, specifically, is related to a kind of apparatus for purifying blood and is filled with the blood purification
Put the blood purification system of structure.
Background technology
Combined artificial kidney is a kind of haemodialysis（HD）Joint blood perfusion（HP）Apparatus for purifying blood, its fully profit
The advantages of with blood perfusion and haemodialysis, have the advantages that good biocompatibility, adverse reaction are few, the blood purification time is short,
And the metabolite, poisonous substance, virulence factor of ESRD can be removed comprehensively, and blood reclaimed water, electrolyte balance are adjusted, can
Long-term dialysis complication is prevented and treated, patients ' life quality is improved, is the therapeutic scheme being widely popularized in clinic.
The blood purification system of existing combined artificial kidney composition includes extracorporeal circulation pipeline and is connected to extracorporeal circulation set tube
Apparatus for purifying blood in road, extracorporeal circulation pipeline include blood circuit arterial line and blood circuit venous line.Such as Fig. 1 institutes
Show, blood circuit arterial line be sequentially provided with direction of flow of blood by transducer potector connect arterial end 01, pump line 02,
Artery kettle 03 and rear port 06；Pump line 02 is embedded in blood pump, and driving source is provided for the blood flow in pump line 02；Artery kettle 03
Artery kettle side pipe 04 is provided with, artery kettle side pipe 04 is provided with stop valve；Transducer potector between artery kettle 03 and rear port 06
It is provided with stop valve 05.Blood circuit venous line is sequentially provided with the front end connected by transducer potector in direction of flow of blood
Mouth 013, venous chambers 014 and vein end 016, venous chambers 014 are provided with venous chambers side pipe 015, and venous chambers side pipe 015, which is provided with, to be cut
Only valve.Apparatus for purifying blood includes intermediate duct and the perfusion device 07 and dialyzer 012 by intermediate duct connection, and intermediate duct exists
It is sequentially provided with direction of flow of blood and is provided with by the front port 09 that transducer potector 08 connects and rear port 011, transducer potector 08
Stop valve 010, front port 09 are connected with the vein port of perfusion device 07, and the artery port of rear port 011 and dialyzer 012 connects
Connect；The artery port of perfusion device 07 forms the artery port of apparatus for purifying blood, and the vein port composition blood of dialyzer 012 is net
Disguise the vein port put；The inner chamber of perfusion device 07 is perfusion chamber, and perfusion chamber is provided with its both ends for preventing from inhaling
The filter screen of attached dose of outflow perfusion chamber；The inner chamber of dialyzer 012 is dialysis chamber, and dialysis chamber is built-in with dialysis membrane, dialysis membrane
Both ends be respectively provided with adhesive-layer.The rear port 06 of blood circuit arterial line is connected with the artery port of apparatus for purifying blood, blood
The front port 013 of liquid loop venous line is connected with the vein port of apparatus for purifying blood.
The clinical treatment mode of the blood purification system is first haemodialysis（HD）Joint blood perfusion（HP）It is small to treat 2
When, then haemodialysis 2 hours is individually carried out, arterial blood is extracted out by the work of blood pump 02 and passes through perfusion device 07 and dialyzer
011 or only pass through the purification of dialyzer 011 after perfusion device 07 is removed, then by blood circuit venous line, will pass through detoxification,
Remove water, be electrolysed in the defeated the Huis' body of blood purified after mass transter, temporarily play a part of substituting human kidney function.
During whole blood purification treatment, following inconvenience or risk be present：（1）, when misoperation, be connected to
The situation of connection loosely occurs in intermediate duct between dialyzer and perfusion device, occurs coming off and making during therapeutic alliance
Into blood loss, and there is also unhandy problem for intermediate duct connection；（2）, in order to avoid being inhaled during pre- rush in perfusion device
Attached dose of fragment is polluted or destroyed to the dialysis membrane in dialyzer, need to connecting line, perfusion device, dialyzer dismantled,
The operation such as refitting, increases the complex operation degree of medical personnel, while existing causes the intrusion blood such as bacterium in air, virus net
Risk in change system, the safety and efficacy for the treatment of is adversely affected；（3）, after therapeutic alliance is completed, need to first tear open
Except perfusion device, then dialyzer is exhausted and could be used, it is not only cumbersome, and potential safety hazard be present；（4）Extracorporal circulatory system
The external blood chamber vol of pipeline length increase patient, increase patient produce the risk of the complication such as low blood pressure.
The content of the invention
The main object of the present invention is to provide a kind of easy to operate and safe apparatus for purifying blood；
It is a further object of the present invention to provide the blood purification system that more than one state apparatus for purifying blood structure.
In order to realize above-mentioned main purpose, apparatus for purifying blood provided by the invention includes perfusion unit, unit with dialysis, company
Order member and control unit.Perfusion unit includes perfusion chamber, and the import of perfusion chamber is the artery port of apparatus for purifying blood.
Unit with dialysis includes dialysis chamber, and the outlet of dialysis chamber is the vein port of apparatus for purifying blood.Connection unit includes shell
And dividing plate, the chamber that dividing plate surrounds shell are separated into separate first chamber and second chamber, first chamber is perfusion
Chamber, second chamber are dialysis chamber.Shell is provided with dialyzate import in the side-walls of dialysis chamber and dialyzate exports.Control
Unit includes controlling switch and outer even port, and controlling switch is used to selectively connecting the outlet of perfusion chamber, dialysis chamber
Both in import and outer connectivity port.
From above scheme, it is saturating with blood to be provided simultaneously with blood perfusion as an entirety for whole apparatus for purifying blood
Function is analysed, more preferable blood purification treatment can be provided for patient.After the connection with body circulation pipeline, nothing during pre- punching
Pipeline dismounting and refitting need to be carried out, it is possible to realize the independent pre- punching to dialysis chamber and perfusion chamber, simplifying the same of operation
When, improve safety in utilization；And after therapeutic alliance, can be without detaching pipelines under conditions of, switch to individually dialysis control
Treat, improve the security for the treatment of.Switched by adjustment control, by the inner chamber environment of perfusion chamber and the inner chamber environment of dialysis chamber
It is mutually isolated, avoid adsorbent fragment that may be present in perfusion chamber from entering in dialysis chamber, the dialysis function to dialysis membrane
Impact, while can accordingly realize that dry and wet preserves by dialysis membrane and different requirements of the adsorbent to storage environment humidity.
Specific scheme is that shell includes cylinder, the first end cap being fastened on the port of the axial end of cylinder first, and
The second end cap being fastened on the port of its second axial end；Dividing plate is along the axial arranged of cylinder；First end cap is relative with dividing plate
The opening position answered, which is provided with, is used to installing the mounting hole of controlling switch, and the opening position corresponding with mounting hole, which is provided with, on dividing plate is used to pacify
The mounting seat of controlling switch is filled, the outlet of perfusion chamber and the import of dialysis chamber are correspondingly located at by the side of mounting seat；Artery
Port opening position corresponding with perfusion chamber on the end wall of the second end cap, vein port is on the end wall of the second end cap
The opening position corresponding with dialysis chamber；Dialyzate import and dialyzate outlet are in the side wall of cylinder.It is simple in construction, it is easy to
Assembling.
More specifically scheme is that dividing plate includes central dividing plate, first partition and second partition；First end is covered provided with the
First accommodating chamber of the axial open at one end of one end cap, the second end cap are provided with open the of axial Single port in the second end cap
Two accommodating chambers；Central dividing plate is made with cylinder in a manner of integrally formed, and the chamber of cylinder is separated into left chamber and right chamber
Room；First partition is made with the first end cap in a manner of integrally formed, and by the first accommodating chamber be separated into the first left accommodating chamber with
First right accommodating chamber；Second partition is made with the second end cap in a manner of integrally formed, and the second accommodating chamber is separated into second
Left accommodating chamber and the second right accommodating chamber；Left chamber, the first left accommodating chamber and the second left accommodating chamber docking form perfusion chamber, right chamber
Room, the first right accommodating chamber and the second right accommodating chamber docking form dialysis chamber；Mounting seat is in first partition.Be easy to manufacture with
Assembling.
One again specific scheme be left chamber close to the end of the first end cap internal face be provided with first in the shaft shoulder, it is close
The internal face of the end of second end cap is provided with the shaft shoulder in second；Perfusion unit is pressed with the end face of first end cap and first between the shaft shoulder
Port of export filter screen, the entrance point filter screen of perfusion unit is pressed with the end face of the second end cap and second between the shaft shoulder；Also include first
Sealing gasket and the second sealing gasket, the first sealing gasket include connected first annular sealing ring portion and the first strip gasket piece portion；The
Two sealing gaskets include the second connected O-ring seal portion and the second strip diaphragm seal portion；First annular sealing ring portion is pressed on first
Between the end face of end cap and the end face of the first axial end, the first strip gasket piece portion is pressed on end face and the central dividing plate of first partition
End face between；Second O-ring seal portion is pressed between the end face of the second end cap and the end face of the second axial end, the second strip
Diaphragm seal portion is pressed between the end face of second partition and the end face of central dividing plate.
Another specific scheme is that the first end cap end face outer rim has convexed to form more than two first pre-determined bits projections
And the first bulge loop positioned at the raised inner side of first pre-determined bit, it has been recessed on the first axial end end face convex with the first pre-determined bit
Act the first pre-determined bit groove being engaged and the first groove to match with the first bulge loop.Second end cap end face outer rim has convexed to form
More than two second pre-determined bits are raised and the second bulge loop positioned at the raised inner side of second pre-determined bit, on the second axial end end face
It is recessed and the second pre-determined bit projection the second pre-determined bit groove being engaged and the second groove to match with the second bulge loop.The
One pre-determined bit is raised with being that permanent type buckle neck is fixedly connected, being adhesively fixed connects or be welded and fixed between the first pre-determined bit groove
Connection, the second pre-determined bit it is raised be between the second pre-determined bit groove permanent type buckle neck be fixedly connected, be adhesively fixed connection or
It is welded and fixed connection.It is easy to the positioning between end cap and cylinder with being fixedly connected, while improves the identification of anti-opening.
Preferable scheme is that controlling switch is set including inner cylinder, outer cylinder and the pedestal in mounting seat, mounting seat
In on dividing plate.Outer cylinder, which can rotatably be placed on outside inner cylinder around own axes and be sealed with inner cylinder, to be coordinated；Pedestal is provided with installation
Circular hole, inner cylinder blind end are fixedly connected with installing the bottom surface of circular hole, and outer cylinder one end is placed in installation circular hole and opposite base
It can rotate around own axes, coordinate between the outside wall surface of outer cylinder and the internal face for installing circular hole for sealing.Pedestal is provided with and filling
Flow the first through hole of chamber outlet connection and the second through hole with dialysis chamber inlet communication, on inner cylinder barrel with first through hole
Corresponding opening position is provided with third through-hole and the opening position corresponding with the second through hole is provided with fourth hole；The barrel of outer cylinder
It is provided with more than two intercommunicating pores；Outer cylinder rotates around own axes, and intercommunicating pore selectively only connects first through hole and the
Three through holes, or only connect the second through hole and fourth hole, or first through hole and third through-hole and the second through hole and the are connected simultaneously
Four through holes；Port of the inner cylinder away from blind end is outer even port.
One preferred scheme is first through hole, the second through hole, third through-hole and fourth hole coaxial line and the axis
It is mutually orthogonal with the plate face of dividing plate；Intercommunicating pore includes the first intercommunicating pore, the second intercommunicating pore and third connecting hole；First intercommunicating pore and
The two intercommunicating pore coaxial lines and axis and the axis in third connecting hole are mutually orthogonal.
Another preferable scheme is that outer cylinder can move relative to inner cylinder along itself axial reciprocating；The outer tube wall of inner cylinder
The spacing outer shaft shoulder is provided with, the inner tube wall of outer cylinder is provided with the spacing interior shaft shoulder, and the spacing outer shaft shoulder mutually supports with the spacing interior shaft shoulder
By forming outer cylinder away from the spacing of pedestal；Head face hump of the outer cylinder away from outer even port forms locating piece, installs circular hole
Formed with the locating slot to match with locating piece on bottom surface, locating slot includes the first locating slot, the second locating slot and the 3rd positioning
Groove；Outer cylinder is more than the maximum length of locating piece insertion locating slot along itself axially movable distance；Locating piece is located at first
When in locating slot, intercommunicating pore connects first through hole and third through-hole and the second through hole and fourth hole simultaneously；Locating piece is positioned at the
When in two locating slots, intercommunicating pore only connects first through hole and third through-hole；When locating piece is located in the 3rd locating slot, intercommunicating pore is only
Connect the second through hole and fourth hole.
In order to realize above-mentioned another object, blood purification system provided by the invention includes extracorporeal circulation pipeline and is connected to
Apparatus for purifying blood in the extracorporeal circulation pipeline.Wherein, apparatus for purifying blood is the blood described by any of the above-described technical scheme
Liquid purifier.
Specific scheme is that extracorporeal circulation pipeline includes blood circuit arterial line, blood circuit venous line, the one or three
Logical, the first artery branch pipe, the second artery branch pipe, the second threeway, intervalve, the 3rd threeway, the first vein branch pipe and the second vein
Branch pipe.The first interface of first threeway is connected with the rear port of blood circuit arterial line, second interface and the first artery branch pipe
Single port connection, the 3rd interface is connected with the Single port of the second artery branch pipe；The another port of first artery branch pipe and artery
Port connects；The first interface of second threeway connects with the another port of the second artery branch pipe, and the one of second interface and intervalve
Port is connected, and the 3rd interface is connected with the Single port of the second vein branch pipe；The another port of intervalve is connected with outer even port；The
The first interface of three threeways is connected with the another port of the second vein branch pipe；Second interface and the Single port of the first vein branch pipe connect
Connect, the 3rd interface is connected with the front port of blood circuit venous line；The another port of second vein branch pipe connects with vein port
Connect；Stop valve is equipped with first artery branch pipe, the second artery branch pipe, intervalve, the first vein branch pipe and the second vein branch pipe.
Brief description of the drawings
Fig. 1 is the connection diagram of the extracorporeal circulation pipeline and perfusion device and dialyzer of existing blood purification system；
Fig. 2 is the structural representation of apparatus for purifying blood in blood purification system first embodiment of the present invention；
Fig. 3 is A partial enlarged drawings in Fig. 2；
Fig. 4 is B partial enlarged drawings in Fig. 2；
Fig. 5 is C partial enlarged drawings in Fig. 2；
Fig. 6 is D partial enlarged drawings in Fig. 2；
Fig. 7 is the top view of the cylinder of apparatus for purifying blood in blood purification system first embodiment of the present invention；
Fig. 8 is the upward view of the first end cap of apparatus for purifying blood in blood purification system first embodiment of the present invention；
Fig. 9 is the structural representation of the first sealing gasket of apparatus for purifying blood in blood purification system first embodiment of the present invention
Figure；
Figure 10 is the top view of the second end cap of apparatus for purifying blood in blood purification system first embodiment of the present invention；
Figure 11 is that the structure of the second sealing gasket of apparatus for purifying blood in blood purification system first embodiment of the present invention is shown
It is intended to；
Figure 12 is the structural representation of the control unit of apparatus for purifying blood in blood purification system first embodiment of the present invention
Figure；
Figure 13 is the top view of the control unit of apparatus for purifying blood in blood purification system first embodiment of the present invention；
Figure 14 is the working condition of the controlling switch of apparatus for purifying blood in blood purification system first embodiment of the present invention
Schematic diagram；
Figure 15 is the connection diagram of pipeline and apparatus for purifying blood in blood purification system first embodiment of the present invention；
Figure 16 is the structural representation of the controlling switch of apparatus for purifying blood in blood purification system second embodiment of the present invention
Figure；
Figure 17 is the structural representation of apparatus for purifying blood in blood purification system 3rd embodiment of the present invention；
Figure 18 is the top view of the first end cap of apparatus for purifying blood in blood purification system 3rd embodiment of the present invention；
Figure 19 is the structural representation of controlling switch in blood purification system fourth embodiment of the present invention；
Figure 20 is the top view of the cylinder of apparatus for purifying blood in blood purification system sixth embodiment of the present invention；
Figure 21 is the upward view of the first end cap of apparatus for purifying blood in blood purification system sixth embodiment of the present invention.
With reference to embodiments and its accompanying drawing the invention will be further described.
Embodiment
The present invention is mainly improved to the structure of apparatus for purifying blood in blood purification system, be related to absorbing unit with
The structure of connection unit and control unit between filter element, while to improve blood purification treatment security, simplify doctor
The operating process of shield personnel, the other parts structure of blood purification system are designed according to existing product.
Following embodiment is mainly for blood purification system of the invention, because blood purification system of the present invention employs
The apparatus for purifying blood of the present invention, included to apparatus for purifying blood embodiment in the explanation of blood purification system embodiment
Explanation.
Blood purification system first embodiment
Blood purification system is made up of apparatus for purifying blood, extracorporeal circulation pipeline and dialysis liquid pipeline, apparatus for purifying blood
It is made up of perfusion unit, unit with dialysis, connection unit and control unit.Control unit is made up of controlling switch and outer even port.
Connection unit is made up of shell and dividing plate, and the inner chamber that dividing plate surrounds shell is separated into separate first chamber
With second chamber, first chamber is the perfusion chamber of perfusion unit, and second chamber is the dialysis chamber of unit with dialysis.
Referring to Fig. 2, shell is by cylinder 11, the first end cap 12 on the port for the first axial end for being fastened on cylinder 11, and
The second end cap 13 being fastened on the port of the second axial end of cylinder 11 is formed.Dividing plate by central dividing plate 141, first partition and
Second partition 143 is formed.
Referring to Fig. 2 to Fig. 7, cylinder 11 is a circular cylinder body, central dividing plate 141 and the system in a manner of integrally formed of cylinder 11
The chamber of cylinder 11 is separated into left chamber 111 and right chamber room 112 into, central dividing plate 141 along the axial arranged of cylinder 11, with
Make perfusion chamber arrangement parallel with the axial direction of dialysis chamber.The side wall of left chamber 111 is the smooth company being made up of arcwall face
Continuous curved surface, avoids blood perfusion process from forming blood dead angle, to reduce blood coagulation risk.The upper port of left chamber 111 it is interior
Formed with the shaft shoulder 1111 in first on wall, formed with the shaft shoulder 1112 in second on the internal face of lower port, the shaft shoulder 1111 in first
On be equipped with port of export filter screen 151, be equipped with entrance point filter screen 152 on the shaft shoulder 1112 in second, left inside chamber 111 is located at port of export filter screen
Section chambers between 151 and entrance point filter screen 152 form the accommodating chamber for accommodating adsorbent 1110.Adsorbent 1110 can be
One or more of combinations in the blood-purifying adsorbing agents such as resin sorbent, acticarbon, natural macromolecule adsorbent.
Port of export filter screen 151 is by the rack 1511 that is supported in first on the shaft shoulder 1111 and is fixed on the port of rack 1511
Mesh sheet 1512 form, for preventing adsorbent 1110 from being flowed out from the upper port of left chamber 111, entrance point filter screen 152 is by supporting
Formed in the rack 1521 in second on the shaft shoulder 1112 and the mesh sheet 1522 being fixed at the port of rack 1521, for preventing from adsorbing
Agent 1110 is flowed out from the lower port of left chamber 111.
Bonding glue-line 1120 is provided with the upper and lower ends mouth of right chamber room 112, is dialysis membrane between two bonding glue-lines 1120
1121, dialysis membrane 1121 can be the hemodialysis membrane of the materials such as polyether sulfone, polysulfones, polypropylene.
Side-walls of the barrel of cylinder 11 in right chamber room 112 are provided with dialyzate import 104 and dialyzate outlet 103, dialysis
Liquid import 104 is sealed by dialyzate import block 108, and dialyzate outlet 103 is sealed by dialyzate outlet block 107.
Referring to Fig. 2 to Fig. 8, the end face outer rim of the first axial end of cylinder 11 has been recessed two the first pre-determined bit grooves
113, the center line of two the first pre-determined bit grooves 113 is conllinear and is mutually perpendicular to the plate face of central dividing plate 121, the first axial end end face
Radial direction in the middle part of be recessed with the coaxial line of cylinder 11 arrangement the first groove 114.The end face of first end cap 12 and first pre-
The corresponding opening position of locating slot 113 has convexed to form the first pre-determined bit projection 123, the position corresponding with the first groove 114
Place convexes to form the first bulge loop 124 being engaged with the first groove 114.Formed on the madial wall of first pre-determined bit projection 123
There is a buckle, formed with the neck to match with buckle on the bottom surface 1131 of the first pre-determined bit groove 113.When the first end cap 12 is fastened on
When on the first axial end of cylinder 11, cooperation and the first pre-determined bit projection 123 by the first bulge loop 124 and the first groove 114
With the cooperation of the first pre-determined bit groove 113, the first end cap 12 and the pre-determined bit of the axial end of cylinder 11 first diametrically are realized, simultaneously
Realize that mechanical seal therebetween coordinates；By on the buckle in the first pre-determined bit projection 123 and the first pre-determined bit groove 113
Neck forms the connection of permanent type buckle neck, for the first end cap 12 and the axial end of cylinder 11 first cooperation realize it is circumferentially positioned,
Realize being fixedly connected for the two simultaneously.
First end cap 12 is made with first partition 142 in a manner of integrally formed, and the first end cap 12 is provided with axially
First accommodating chamber of open at one end, the first accommodating chamber it is open towards the direction of cylinder 11.First partition 142 is by the first accommodating chamber
The first left 121 and first right accommodating chamber 122 of accommodating chamber is separated into, the first left accommodating chamber 121 is interior with the first right accommodating chamber 122
Wall is smooth continuous curve surface.
The radial direction central position of first end cap 12 formed with the mounting hole 120 for installing controlling switch 17, first every
The opening position corresponding with mounting hole 120 is provided with the mounting seat 1422 for being used for installing controlling switch 17, mounting hole 120 on plate 142
Cross section with mounting seat 1422 is cross-shaped configuration.First partition 142 towards cylinder 11 head face hump formed with two
Positioning convex 1421, it is correspondingly located at the both sides of mounting seat 1422.
Sealed between first axial end of the first end cap 12 and cylinder 11 by the first sealing gasket 161 as shown in Figure 9,
First sealing gasket 161 is made up of the first annular sealing ring portion 1610 being connected with the first strip gasket piece portion 1611, first
Shape diaphragm seal portion 1611 is towards being recessed two positioning being engaged with positioning convex 1421 on the end face direction of cylinder 11
Groove 1612.First annular sealing ring portion 1610 is pressed on the end face of the first end cap 12 and the end face of the first axial end of cylinder 11
Between, the first strip gasket piece portion 1611 is pressed between the end face of first partition 142 and the end face of central dividing plate 141.
By the cooperation of positioning convex 1421 and detent 1612, realize to the fast positioning of the first sealing gasket 161 and
It is quick to be fixedly mounted.
Referring to Fig. 2 to Fig. 6 and Figure 10, the end face outer rim of the second axial end of cylinder 11 has been recessed the second pre-determined bit groove
115, the center line of two pre-determined bit grooves 115 is conllinear and is mutually perpendicular to the plate face of central dividing plate 121, the end face of the second axial end
Radially middle part is recessed the second groove 116 with the coaxial line of cylinder 11 arrangement.The end face of second end cap 13 is predetermined with second
Groove 115 corresponding opening position in position has convexed to form the second pre-determined bit projection 133, the opening position corresponding with the second groove 116
Convex to form the second bulge loop 134 being engaged with the second groove 116.On the madial wall of second pre-determined bit projection 133 formed with
Buckle, formed with the neck to match with buckle on the bottom surface 1151 of the second pre-determined bit groove 115, when the second end cap 13 is fastened on
It is predetermined by the cooperation of the second bulge loop 134 and the second groove 116 and the second pre-determined bit projection 133 and second when on two axial ends
The cooperation of position groove 115, the second end cap 13 and the positioning of the axial end of cylinder 11 second diametrically are realized, while realized therebetween
Mechanical seal coordinate；Formed forever by the neck on the buckle in the second pre-determined bit projection 133 and the second pre-determined bit groove 115
Type buckle neck is connected, and fixation that is circumferentially positioned, while realizing the two is realized in the cooperation for the second end cap 13 and the second axial end
Connection.
Second end cap 13 is made with second partition 143 in a manner of integrally formed, and the second end cap 13 is provided with axially
Second accommodating chamber of open at one end, the second accommodating chamber it is open towards the direction of cylinder 11.Second partition 143 is by the second accommodating chamber
It is separated into the second left 131 and second right accommodating chamber 132 of accommodating chamber, the inwall of the second left 131 and second right accommodating chamber 132 of accommodating chamber
Face is smooth continuous curve surface.
Second end cap 13 opening position corresponding with the second left accommodating chamber 131 is provided with blood mouth as artery port 101, that is, fills
The import of chamber is flowed, artery port 101 is sealed by artery port cap cap 105；Second end cap 13 is relative with the second right accommodating chamber 132
The opening position answered is provided with outlet of the blood mouth as vein port 102, i.e. dialysis chamber, and vein port 102 is by vein port cap cap
106 sealings.Second partition 143 towards cylinder 11 head face hump formed with positioning convex 1431.
Sealed between second axial end of the second end cap 13 and cylinder 11 by the second sealing gasket 162 as shown in figure 11,
Second sealing gasket 162 is made up of the second O-ring seal portion 1620 being connected with the second strip diaphragm seal portion 1621, Article 2
Shape diaphragm seal portion 1621 is towards being recessed the detent that is engaged with positioning convex 1431 on the end face direction of cylinder 11
1622.Second O-ring seal portion 1620 is pressed between the end face of the second end cap 13 and the end face of the second axial end of cylinder 11, the
Two strip gasket piece portions 1621 are pressed between the end face of second partition 143 and the end face of central dividing plate 141.
By the cooperation of positioning convex 1431 and detent 1622, realize to the fast positioning of the second sealing gasket 162 and
It is quick to be fixedly mounted.
When the first end cap 12 is fastened on the port of the first axial end of cylinder 11, and the second end cap 13 is fastened on cylinder 11
The second axial end port on when, the first left accommodating chamber 121, the docking of left chamber 111 and second left accommodating chamber 131 form perfusion
Chamber, and the medial surface of perfusion chamber is a smooth continuous curve surface, reduces the risk for blood coagulation occur.First right accommodating chamber 122,
112 and second right accommodating chamber 132 docking of right chamber room forms dialysis chamber, and the medial surface of dialysis chamber is a smooth continuous song
Face.
Referring to Fig. 2, Figure 12, Figure 13 and Figure 14, controlling switch 17 is made up of pedestal 173, outer cylinder 172 and inner cylinder 171.
The lateral surface of pedestal 173 is the cross-shaped configuration that is engaged with mounting hole 120 and mounting seat 1422, be easy to positioning and
It is circumferentially fixed, and pedestal 173 is made up of elaxtic seal, when pedestal 173 is attached to mounting hole 120 with mounting seat 1422
When, by the mode such as welding or being bonded, pedestal 173 is fixed with the side wall of mounting hole 120 and mounting seat 1422 for sealing
Connection, while pedestal 173 is real by the first strip gasket piece portion 1611 and the end face of central dividing plate 141 towards the end face of cylinder 11
Now sealing coordinates, and so as to effectively keep the separate of perfusion chamber and dialysis chamber, i.e., can only be opened between the two by controlling
Close 17, artery port 101 and vein port 102 is interconnected, when this three closes, perfusion chamber will be kept with dialysis chamber
It is mutually isolated.
The one end of the barrel 1710 of inner cylinder 171 away from pedestal 173 connects end provided with blood mouth as the outer of the present embodiment
Mouth 1711, outer even port 1711 are sealed by outer even port block 109, and the one end of barrel 1710 away from outer even port is to close
Hold, formed with third through-hole 1712 and fourth hole 1713 on the barrel of blind end, the outer tube wall of barrel 1710 is in threeway
Hole 1712 and the top of fourth hole 1713 form limited location outer shaft shoulder 1716, and third through-hole 1712 is coaxial with fourth hole 1713
Line is arranged and the axis normal of the axis and inner cylinder 171.The head face hump of blind end is formed with positioning convex 1714.
One end outer wall of the barrel 1720 of outer cylinder 172 away from pedestal 173 has convexed to form knob 1721, inner side barrel
The opening position corresponding with the spacing outer shaft shoulder 1716 is formed with the spacing interior shaft shoulder 1724 being engaged with the spacing outer shaft shoulder 1716, far
From outer even on the barrel of one end of port 1711 formed with the first intercommunicating pore 1722, the second intercommunicating pore 1723 and third connecting hole
1726, the first intercommunicating pore 1722 and the axis normal of the coaxial line of the second intercommunicating pore 1723 arrangement and the axis and outer cylinder 172.
Head face hump of the barrel 1720 away from port 1711 is formed with two pieces of locating convex blocks 1725.
Pedestal 173 is provided with the installation circular hole 1731 that cooperation is mutually sealed with the outer peripheral face of outer cylinder 172, and pedestal 173 is with filling
Flow formed with the first through hole 1732 for connecting the side with installing circular hole 1731 on the corresponding side of chamber, with dialysis chamber phase
It is logical formed with the second through hole 1733 for connecting the side with installing circular hole 1731, first through hole 1731 and second on corresponding side
The axis normal of the coaxial line arrangement of hole 1733 and the axis and installation circular hole 1731.The bottom surface of installation circular hole 1731 is recessed
There are the three pairs of detents 1734 for being engaged detent 1735 with positioning convex 1714 and matching with locating convex block 1725.
By the cooperation of positioning convex 1714 and detent 1735, the fast positioning of inner cylinder 171 and pedestal 173 is realized
And the bonding connection between the end face and installation circular hole 1731 bottom surface for passing through the blind end of inner cylinder 171, realize inner cylinder 171 and pedestal
173 are fixedly connected.
The opposite base 173 of outer cylinder 172 and inner cylinder 171 can rotate around own axes, while can be along itself axial reciprocating
It is mobile.Outer cylinder 172 can be inserted into detent with respect to 171 axially mobile distance of inner cylinder more than locating convex block 1725
Maximum length in 1734, and in outer cylinder 172 along itself axial direction moving process to close to port 1711, when spacing
When the interior shaft shoulder 1724 is against the spacing outer shaft shoulder 1716, locating convex block 1725 departs from stop of the detent 1734 to it, makes cylindrical
Cylinder 172 can rotate around own axes.
When locating convex block 1725 is in first pair of detent 1734, it is logical that the first intercommunicating pore 1722 is used for connection first
Hole 1732 and third through-hole 1712, the second intercommunicating pore 1723 are used to connect the second through hole 1733 and fourth hole 1713, now, filled
Flow chamber outlet by first through hole 1732, the first intercommunicating pore 1722, third through-hole 1712, inner cylinder 171 inner chamber 1715,
Fourth hole 1713, the second intercommunicating pore 1723 and the second through hole 1733 and the inlet communication of dialysis chamber, and perfusion chamber goes out
The import of mouth and dialysis chamber is connected by chamber 1715 with port 1711.
As shown in figure 14, when outer cylinder 172 is located at second pair with respect to 90 degree of inner cylinder rotate counterclockwise, locating convex block 1725
In detent 1734, third connecting hole 1726 is used to connect first through hole 1732 and third through-hole 1712, now, perfusion chamber
Outlet is connected by first through hole 1732, third connecting hole 1726, third through-hole 1712 and inner chamber 1715 with port 1711, and saturating
The import of analysis chamber is in closed state.
When outer cylinder 172 continues rotate counterclockwise 180 degree with respect to inner cylinder, it is recessed that locating convex block 1725 is located at the 3rd pair of positioning
In groove 1734, third connecting hole 1726 is used to connect the second through hole 1733 and fourth hole 1713, and now, dialysis chamber import is led to
The second through hole 1733, third connecting hole 1726, fourth hole 1713 and inner chamber 1715 is crossed to be connected with port 1711, and perfusion chamber
Outlet be in closed state.
Corresponding position is provided with the distinguishing mark corresponding with above-mentioned three kinds of states on the outer face of the first end cap 12, just
In operation of the operating personnel to controlling switch 17.And after the switching of completion status, along outer cylinder 172 axially by locating convex block
1725 press in corresponding detent 1734, realize the locking of state.When needing to change connection status, need first by outer cylinder
172 lift and switch over state again, effectively prevent unexpected touch and change connection status, to the security of blood purification treatment
Impact.
After the assembling of apparatus for purifying blood 1 is completed, make locating convex block 1725 in second pair of detent 1734, resistance
Disconnected connection between perfusion chamber outlet and dialysis chamber import, the hygrometric state that perfusion chamber interior environment can be achieved preserve, and saturating
The interior environment for analysing chamber preserves for dry state.
Referring to Figure 15, extracorporeal circulation set tube route blood circuit arterial line 2, blood circuit venous line 3, the first threeway
41st, the first artery branch pipe 42, the second artery branch pipe 43, the second threeway 44, intermediate duct 45, the 3rd threeway 46, the first venous branch
Pipe 47, the second vein branch pipe 48 and accordingly located at the first artery branch pipe 42, the second artery branch pipe 43, intermediate duct 45, first
Vein branch pipe 47, the stop valve 421 on the second vein branch pipe 48, stop valve 431, stop valve 451, stop valve 471, stop valve
481 are formed.
The rear port of blood circuit arterial line 2 is connected with the first interface of the first threeway 41, blood circuit venous line 3
Front port be connected with the 3rd interface of the 3rd threeway 46.
The Single port of first artery branch pipe 42 is connected with the second interface of the first threeway 41, and another port fills with blood purification
1 artery port 101 is put to connect.
The Single port of second artery branch pipe 43 is connected with the 3rd interface of the first threeway 41, another port and the second threeway 44
First interface connection.
The Single port of intermediate duct 45 is connected with the second interface of the second threeway 44, another port and in controlling switch 17
Outer even port 1711 connects.
The Single port of first vein branch pipe 47 is connected with the second interface of the 3rd threeway 46, and another port fills with blood purification
1 vein port 102 is put to connect.
The Single port of second vein branch pipe 48 is connected with the 3rd interface of the second threeway 44, another port and the 3rd threeway 46
First interface connection.
After connecting extracorporeal circulation pipeline, outer connecting leg 51 is connected in dialyzate import 104 and in dialyzate outlet 103
The outer connecting leg 52 of connection.
Blood purification system is rushed in advance, it is as follows to break through journey in advance：
（1）Stop valve 421,451,481 is set to be in opening, stop valve 431,471 is closed, locating convex block
1725 in second pair of detent 1734, and pre- fliud flushing enters from blood circuit arterial line 2, passes through the first artery branch pipe
42nd, artery port 101, perfusion chamber, inner chamber 1715, outer even port 1711, intervalve 45, the second vein branch pipe 48 and blood return
Discharged into after road venous line 3 in waste fluid bag, individually pre- punching is carried out to perfusion chamber.
（2）Stop valve 421,481 is closed, and opens stop valve 431,471, it is recessed that locating convex block 1725 is located at the 3rd pair of positioning
In groove 1734, pre- fliud flushing enters from blood circuit arterial line 2, passes through the second artery branch pipe 43, intervalve 45, outer even port
1711st, discharged into after inner chamber 1715, dialysis chamber, the first vein branch pipe 47 and blood circuit venous line 3 in waste fluid bag, to dialysis
Chamber carries out individually pre- punching.
After completing pre- punching, dialyzate import 104 is connected by outer connecting leg 51 with dialyzate source, and dialyzate outlet 103 is logical
Outer connecting leg 52 is crossed to be connected with waste fluid bag.Therapeutic process is as follows：
（1）Therapeutic alliance, it is closed stop valve 431,451,481, stop valve 421,471 is in opening state
State, locating convex block 1725 is in first pair of detent 1734.Blood is through blood circuit arterial line 2, the first artery branch pipe
42nd, artery port 101 enters in perfusion chamber and blood is adsorbed, and the blood after being adsorbed is entered by controlling switch 17
In dialysis chamber, blood is dialysed in dialysis chamber, the blood after being dialyzed is through vein port 102, the first vein
After branch pipe 47 and blood circuit venous line 3 in defeated the Huis' body, therapeutic alliance was completed after 2 hours.
（2）Independent dialysis treatment, it is closed stop valve 421,481, stop valve 431,451,471, which is in, to be opened
State, locating convex block 1725 is in the 3rd pair of detent 1734.Blood is through blood circuit arterial line 2, the second artery branch
Pipe 43, intermediate duct 45, inner chamber 1715 are individually dialysed into dialysis chamber to blood, and the blood after being dialyzed passes through quiet
In arteries and veins port 102, the first vein branch pipe 47 and the defeated the Huis' body of blood circuit venous line 3, individually dialysis was completed after 2 hours and is controlled
Treat.
When perfusion unit or the unit with dialysis part exception of over the course for the treatment of, such as happening suddenly, or need to adjust it immediately
In a certain unit treatment time, or due to when other reasons need to stop the treatment of a certain unit, without shutting down and taking apart purification
Device and pipeline.For example if desired for perfusion treatment is stopped, retaining dialysis treatment, be closed stop valve 421,481, cut
Only valve 431,451,471 is in opening, and locating convex block 1725 is in the 3rd pair of detent 1734.Such as need to stop dialysing
Treatment, retaining perfusion treatment, stop valve 421,451,481 is in opening, stop valve 431,471 is closed,
Locating convex block 1725 is in second pair of detent 1734.
In the present embodiment, the thickness of dividing plate is between 3 millimeters to 10 millimeters, at close first end cap, dividing plate
Thickness gradually increases, and while in order to installation to controlling switch, keeps the smooth continuous of perfusion chamber interior sidewall surface.First
The quantity of the groove 116 of groove 114 and second is more than one, is usually chosen to 2 to 4.In order to realize pre-determined bit groove and pre-determined bit
Raised fast positioning, marks in the end cap position corresponding with cylinder, or the pre-determined bit groove tool on same axial end
There are different shape or size.
Blood purification system second embodiment
It is only pair real with blood purification system first below as the explanation to blood purification system second embodiment of the present invention
The difference for applying example illustrates.
Referring to Figure 16, the end of positioning convex 5714 on the blind end of the inner cylinder 571 of controlling switch 57 expand to be formed it is swollen
Swollen end, detent 5734 on the installation circular hole bottom surface of pedestal 573 formed with the inflation lumen being engaged with expanding end,
Being fixedly connected inner cylinder 571 and pedestal 573 is realized by the cooperation of expanding end and inflation lumen.
Blood purification system 3rd embodiment
As the explanation to blood purification system 3rd embodiment of the present invention, below only pair with above-mentioned blood purification system the
The difference of one embodiment illustrates.
Referring to Figure 17 and Figure 18, knob 6721 and barrel 6720 in the outer cylinder 672 of controlling switch are dismountable
It is fixedly connected, the mounting hole 620 being formed on the first end cap 62 is the circular port to match with the outer peripheral face of outer cylinder 672.
Compression by the first end cap 62 to the pedestal 673 made of elaxtic seal, realizes pedestal 673 and first end
Sealing between lid 62 coordinates and the fixation to controlling switch.
Blood purification system fourth embodiment
It is only pair real with blood purification system first below as the explanation to blood purification system fourth embodiment of the present invention
The difference for applying example illustrates.
Referring to Figure 19, there was only the first intercommunicating pore 7722 and the second intercommunicating pore 7723 in outer cylinder 772, as shown in the figure state,
First intercommunicating pore 7722 connects first through hole 7712 and third through-hole 7732, the second intercommunicating pore 7723 connect the second through hole 7713 and
Fourth hole 7733.
When the rotated counterclockwise by angle of outer cylinder 772 is equal to the center line angle of the first intercommunicating pore 7722 and the second intercommunicating pore 7723
When, the second intercommunicating pore 7723 connection first through hole 7712 and third through-hole 7732, and the second through hole 7713 and fourth hole 7733
Do not connect.
When outer cylinder 772, rotated counterclockwise by angle subtracts the first intercommunicating pore 7722 and the second intercommunicating pore equal to 360 degree again
At twice of 7723 center line angle, the first intercommunicating pore 7722 connects the second through hole 7713 and fourth hole 7733, and first is logical
Hole 7712 does not connect with third through-hole 7732.
The axis of first intercommunicating pore 7722 is not conllinear with the axis of the second intercommunicating pore 7723, and angle is usual between the two axis
Elect 90 degree to 150 degree as.
The embodiment of blood purification system the 5th
It is only pair real with blood purification system first below as the explanation to the embodiment of blood purification system the 5th of the present invention
The difference for applying example illustrates.
Omit the raised buckle and the first pre-determined bit groove and the second pre-determined bit with the second pre-determined bit projection of the first pre-determined bit
Neck on groove.
It is by using bonding agent or ultra-sonic welded that pre-determined bit is raised be bonded with being carried out between pre-determined bit groove or weld and consolidate
Fixed connection.
Blood purification system sixth embodiment
As the explanation to blood purification system sixth embodiment of the present invention, only blood purification system first is implemented below
The difference of example illustrates.
It is raised and located at them to omit the first pre-determined bit groove, the first pre-determined bit projection, the second pre-determined bit groove, the second pre-determined bit
On buckle and neck.
Referring to Figure 20 and Figure 21, the first axial end lateral wall of cylinder 81 is provided with the first outer shaft shoulder 813, the first end cap 82
The upper opening position corresponding with the first outer shaft shoulder 813 is axially extending formed with first annular periphery 823 along cylinder 81.
The lateral wall of first axial end is formed with fin, and the medial surface of first annular periphery with fin formed with being engaged
End cap and the positioning of cylinder in the circumferential are realized in the cooperation of groove, fin and groove, and use bonding agent or ultra-sonic welded by ring
Carry out be bonded between shape periphery and the outer end wall of cylinder or weld and be fixedly connected.
Being fixedly connected between mode and the first end cap 82 and cylinder 81 is fixedly connected between second end cap and cylinder 81
Mode is identical, will not be repeated here.
The central scope of the present invention is by setting attachment structure, controlling switch and outer between perfusion unit and unit with dialysis
Even port, while to improve blood purification treatment security, simplify the operating process of medical personnel.According to this design, control
The structure of switch also has a variety of obvious changes；The structure of shell also has a variety of obvious changes, such as cylinder
Cross section is the shapes such as ellipse or rectangle；Attachment structure between end cap and cylinder also has a variety of obvious changes, than
Such as threaded connection.
Claims (10)
1. apparatus for purifying blood, including perfusion unit, unit with dialysis, connection unit and control unit；
The perfusion unit includes perfusion chamber, and the import of the perfusion chamber is the artery port of the apparatus for purifying blood；
The unit with dialysis includes dialysis chamber, and the outlet of the dialysis chamber is the vein port of the apparatus for purifying blood；
It is characterized in that：
The connection unit includes shell and dividing plate, and the chamber that the shell surrounds is separated into separate by the dividing plate
One chamber and second chamber, the first chamber are the perfusion chamber, and the second chamber is the dialysis chamber；
The shell is provided with dialyzate import in the side-walls of the dialysis chamber and dialyzate exports；
Described control unit includes controlling switch and outer even port, the controlling switch are used to selectively connect the perfusion chamber
The two in the exporting of room, the import of the dialysis chamber and the outer even port；
Can be mutually isolated by the inner chamber of the perfusion chamber and the inner chamber of the dialysis chamber by adjusting the controlling switch.
2. apparatus for purifying blood according to claim 1, it is characterised in that：
The shell includes cylinder, the first end cap being fastened on the port of the axial end of cylinder first, and is fastened on described
The second end cap on the port of second axial end of cylinder；
The dividing plate is axial arranged along the cylinder；
First end cap opening position corresponding with the dividing plate is provided with the mounting hole for being used for installing the controlling switch, described
The opening position corresponding with the mounting hole is provided with the mounting seat for being used for installing the controlling switch, the perfusion chamber on dividing plate
Outlet be correspondingly located at the import of the dialysis chamber by the side of the mounting seat；
Artery port opening position corresponding with the perfusion chamber on the end wall of second end cap, the vein
Port opening position corresponding with the dialysis chamber on the end wall of second end cap；
The dialyzate import and dialyzate outlet are in the side wall of the cylinder.
3. apparatus for purifying blood according to claim 2, it is characterised in that：
The dividing plate includes central dividing plate, first partition and second partition；
The first end covers the first accommodating chamber provided with the axial open at one end in first end cap, on second end cap
Provided with the second accommodating chamber that the axial Single port in second end cap is open；
The central dividing plate is made with the cylinder in a manner of integrally formed, and the chamber of the cylinder is separated into left chamber
With right chamber room；
The first partition is made with first end cap in a manner of integrally formed, and first accommodating chamber is separated into
One left accommodating chamber and the first right accommodating chamber；
The second partition is made with second end cap in a manner of integrally formed, and second accommodating chamber is separated into
Two left accommodating chambers and the second right accommodating chamber；
The left chamber, the first left accommodating chamber and the second left accommodating chamber docking form the perfusion chamber, the right side
Chamber, the first right accommodating chamber and the second right accommodating chamber docking form the dialysis chamber；
The mounting seat is in the first partition.
4. apparatus for purifying blood according to claim 3, it is characterised in that：
Internal face of the left chamber close to the end of first end cap is provided with the shaft shoulder in first, close to second end cap
The internal face of end is provided with the shaft shoulder in second；
It is pressed with the port of export filter screen of the perfusion unit in the end face of first end cap and described first between the shaft shoulder, described second
The entrance point filter screen of the perfusion unit is pressed with the end face of end cap and described second between the shaft shoulder；
Also include the first sealing gasket and the second sealing gasket, first sealing gasket includes connected first annular sealing ring portion and the
One strip gasket piece portion, second sealing gasket include the second connected O-ring seal portion and the second strip diaphragm seal portion；
The first annular sealing ring portion is pressed between the end face of first end cap and the end face of first axial end, described
First strip gasket piece portion is pressed between the end face of the first partition and the end face of the central dividing plate；
The second O-ring seal portion is pressed between the end face of second end cap and the end face of second axial end, described
Second strip diaphragm seal portion is pressed between the end face of the second partition and the end face of the central dividing plate.
5. apparatus for purifying blood according to claim 3, it is characterised in that：
It is raised and pre- positioned at described first that the end face outer rim of first end cap has convexed to form more than two first pre-determined bits
The first bulge loop on the inside of positioning convex；
The first pre-determined bit groove being engaged with the first pre-determined bit projection is recessed on the end face of first axial end
And the first groove to match with first bulge loop；
It is raised and pre- positioned at described second that the end face outer rim of second end cap has convexed to form more than two second pre-determined bits
The second bulge loop on the inside of positioning convex；
The second pre-determined bit groove being engaged with the second pre-determined bit projection is recessed on the end face of second axial end
And the second groove to match with second bulge loop；
First pre-determined bit is raised to be fixedly connected, is adhesively fixed for permanent type buckle neck between the first pre-determined bit groove
Connect or be welded and fixed connection；
Second pre-determined bit is raised to be fixedly connected, is adhesively fixed for permanent type buckle neck between the second pre-determined bit groove
Connect or be welded and fixed connection.
6. according to any one of claim 1 to 5 apparatus for purifying blood, it is characterised in that：
The controlling switch includes inner cylinder, outer cylinder and the pedestal in mounting seat, the mounting seat located at it is described every
On plate；
The outer cylinder, which can rotatably be placed on outside the inner cylinder around own axes and be sealed with the inner cylinder, to be coordinated；
The pedestal is provided with installation circular hole, and the blind end of the inner cylinder is fixedly connected with the bottom surface of the installation circular hole, described
One end of outer cylinder is placed in the installation circular hole and can rotated relative to the pedestal around own axes, the outer wall of the outer cylinder
Coordinate between the internal face of face and the installation circular hole for sealing；
The pedestal is provided with the first through hole of the outlet of the perfusion chamber and connected with the import of the dialysis chamber
The second logical through hole, on the barrel of the inner cylinder opening position corresponding with the first through hole be provided with third through-hole and with institute
State the corresponding opening position of the second through hole and be provided with fourth hole；
The barrel of the outer cylinder is provided with more than two intercommunicating pores；
The outer cylinder rotates around own axes, and the intercommunicating pore selectively only connects the first through hole and the threeway
Hole, or only connect second through hole and the fourth hole, or connect simultaneously the first through hole and the third through-hole and
Second through hole and the fourth hole；
Port of the inner cylinder away from the blind end is the outer even port.
7. apparatus for purifying blood according to claim 6, it is characterised in that：
The first through hole, second through hole, the third through-hole and the fourth hole coaxial line and the axis with it is described
The plate face of dividing plate is mutually orthogonal；
The intercommunicating pore includes the first intercommunicating pore, the second intercommunicating pore and third connecting hole；
First intercommunicating pore is mutual just with the second intercommunicating pore coaxial line and the axis and the axis in the third connecting hole
Hand over.
8. apparatus for purifying blood according to claim 6, it is characterised in that：
The outer cylinder can move relative to the inner cylinder along itself axial reciprocating；
The outer tube wall of the inner cylinder is provided with the spacing outer shaft shoulder, and the inner tube wall of the outer cylinder is provided with the spacing interior shaft shoulder, institute
State the spacing outer shaft shoulder abuts the composition outer cylinder away from the spacing of the pedestal with the spacing interior shaft shoulder；
The outer cylinder away from it is described it is outer even port head face hump formed locating piece, it is described installation circular hole bottom surface on formed with
The locating slot to match with the locating piece, the locating slot include the first locating slot, the second locating slot and the 3rd locating slot；
The outer cylinder is more than the maximum length of the locating piece insertion locating slot along itself axially movable distance；
When the locating piece is located in first locating slot, the intercommunicating pore connects the first through hole and the described 3rd simultaneously
Through hole and second through hole and the fourth hole；
When the locating piece is located in second locating slot, the intercommunicating pore only connects the first through hole and the threeway
Hole；
When the locating piece is located in the 3rd locating slot, the intercommunicating pore only connects second through hole and the four-way
Hole.
9. blood purification system, including extracorporeal circulation pipeline and the apparatus for purifying blood that is connected in the extracorporeal circulation pipeline；
It is characterized in that：
The apparatus for purifying blood is any one of the claim 1 to 8 apparatus for purifying blood.
10. blood purification system according to claim 9, it is characterised in that：
The extracorporeal circulation pipeline includes blood circuit arterial line, blood circuit venous line, the first threeway, the first artery branch
Pipe, the second artery branch pipe, the second threeway, intervalve, the 3rd threeway, the first vein branch pipe and the second vein branch pipe；
The first interface of first threeway is connected with the rear port of the blood circuit arterial line, and the of first threeway
Two interfaces are connected with the Single port of the first artery branch pipe, the 3rd interface and the second artery branch pipe of first threeway
Single port connection；
The another port of the first artery branch pipe is connected with the artery port；
The first interface of second threeway connects with the another port of the second artery branch pipe, and the second of second threeway
Interface is connected with the Single port of the intervalve, the 3rd interface of second threeway and the Single port of the second vein branch pipe
Connection；
The another port of the intervalve is connected with the outer even port；
The first interface of 3rd threeway is connected with the another port of the second vein branch pipe；The second of 3rd threeway
Interface is connected with the Single port of the first vein branch pipe, the 3rd interface and the blood circuit duct of Arantius of the 3rd threeway
The front port connection on road；
The another port of the first vein branch pipe is connected with the vein port；
The first artery branch pipe, the second artery branch pipe, the intervalve, the first vein branch pipe and described second quiet
Stop valve is equipped with pulsation pipe.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510956641.9A CN105457118B (en) | 2015-12-17 | 2015-12-17 | Apparatus for purifying blood and system |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510956641.9A CN105457118B (en) | 2015-12-17 | 2015-12-17 | Apparatus for purifying blood and system |
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| CN105457118B true CN105457118B (en) | 2018-01-02 |
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Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN206630943U (en) * | 2016-10-28 | 2017-11-14 | 珠海健帆生物科技股份有限公司 | Blood purification |
| CN109044825A (en) * | 2018-08-02 | 2018-12-21 | 珠海健帆生物科技股份有限公司 | A kind of soft bag container of haemodialysis concentrate |
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| CN112451772A (en) * | 2020-12-21 | 2021-03-09 | 南通大学附属医院 | But real-time supervision's blood purification device |
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