CN204275132U - A kind of apparatus for purifying blood that synchronously can realize dialysing and perfusion is treated - Google Patents
A kind of apparatus for purifying blood that synchronously can realize dialysing and perfusion is treated Download PDFInfo
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Abstract
本实用新型公开了一种可同步实现透析与灌流治疗的血液净化装置，包括外罐体和分别设于该外罐体两端的血液流入端和血液流出端，外罐体内部设有包含入口端和出口端的灌流单元，入口端与血液流入端相连通，出口端与血液流出端相连通；外罐体还设有与透析液管路连接的透析液进端口和透析液出端口，透析液进端口和透析液出端口与位于外罐体内部的透析液腔相连通；灌流单元包括带孔内罐体、透析膜层和吸附剂，吸附剂填充于带孔内罐体内，透析膜层附着于带孔内罐体上。本实用新型的血液净化装置可以在保持一种治疗模式体外引血量不变的同时达到两种治疗的效果，同时可简化整个治疗体系管路连接等操作的复杂程度。
The utility model discloses a blood purification device capable of synchronously realizing dialysis and perfusion treatment. and the perfusion unit at the outlet end, the inlet end is connected with the blood inflow end, and the outlet end is connected with the blood outflow end; The port and the dialysate outlet port are connected with the dialysate cavity inside the outer tank; the perfusion unit includes an inner tank with holes, a dialysis membrane layer and an adsorbent, the adsorbent is filled in the inner tank with holes, and the dialysis membrane layer is attached to the On the tank body with holes. The blood purification device of the utility model can achieve the effect of two kinds of treatments while keeping the amount of extracorporeal blood drawn in one treatment mode unchanged, and can simplify the complexity of the operation such as pipeline connection of the whole treatment system.
Description
技术领域technical field
本实用新型涉及医疗器械技术领域，具体来说，涉及一种可同步实现透析与灌流治疗的血液净化装置。The utility model relates to the technical field of medical instruments, in particular to a blood purification device which can simultaneously realize dialysis and perfusion treatment.
背景技术Background technique
血液透析(hemodialysis，HD)是急慢性肾功能衰竭患者肾脏替代治疗方式之一。它通过将体内血液引流至体外，经一个由无数根空心纤维组成的透析器中，血液与含机体浓度相似的电解质溶液(透析液)在一根根空心纤维内外，通过弥散/对流进行物质交换，清除体内的代谢废物、维持电解质和酸碱平衡；同时清除体内过多的水分。Hemodialysis (HD) is one of the renal replacement therapies for patients with acute and chronic renal failure. It drains the blood from the body to the outside of the body through a dialyzer composed of countless hollow fibers. The blood and the electrolyte solution (dialysate) with a similar concentration to the body are exchanged through diffusion/convection inside and outside the hollow fibers. , remove metabolic waste in the body, maintain electrolyte and acid-base balance; remove excess water in the body at the same time.
血液灌流(Hemoperfusion，HP)是将患者动脉血引入储有吸附材料的血液灌流装置，通过接触血液使其中的毒物、代谢产物被吸附而净化，然后再回输体内。血液灌流是近几年在临床上迅速崛起的一门新的血液净化技术，治疗范畴已涉及肾脏病、急性中毒、肝病、危重病、皮肤病及免疫性疾病等等。Hemoperfusion (Hemoperfusion, HP) is to introduce the patient's arterial blood into the hemoperfusion device stored with adsorbent materials, and to absorb and purify the poisons and metabolites in the blood through contact with the blood, and then reinfuse it into the body. Hemoperfusion is a new blood purification technology that has emerged rapidly in clinical practice in recent years. Its treatment scope has involved kidney disease, acute poisoning, liver disease, critical illness, skin disease and immune disease, etc.
血液透析(HD)联合血液灌流(HP)的联合治疗模式是目前临床血液净化广为应用的一种治疗模式，在治疗尿毒症及中毒等领域均有广泛的应用，其充分地利用血液灌流器与血液透析器的优点，具有生物相容性好、不良反应少等优点，同时可综合发挥透析与灌流针对不同毒素的清除效果，能够全面清除尿毒症、中毒等病患体内的各种毒素。The combined treatment mode of hemodialysis (HD) combined with hemoperfusion (HP) is a treatment mode widely used in clinical blood purification at present, and it is widely used in the treatment of uremia and poisoning. Compared with hemodialyzer, it has the advantages of good biocompatibility and less adverse reactions. At the same time, it can comprehensively exert the removal effect of dialysis and perfusion for different toxins, and can comprehensively remove various toxins in patients with uremia and poisoning.
目前组合型人工肾等HD+HP治疗模式的实现是通过联合使用独立的透析器和灌流器，在分别对透析器和灌流器进行预冲并采用管路进行连接后进行联合治疗。在治疗过程中通过将患者血液先通过透析器再通过灌流器的方法。此治疗模式的问题在于由于血液是分别独立通过透析器和灌流器，血液流过一种装置时只能进行一种治疗，而为了获得两种治疗效果将两种装置的串联组合则增大了整个治疗装置的血室容积，增大患者引出体外的血液量，增加治疗风险。At present, combined artificial kidney and other HD+HP treatment modes are achieved through the joint use of independent dialyzers and perfusion devices, and combined treatment is performed after the dialyzers and perfusion devices are prefilled and connected with pipelines. During the treatment process, the patient's blood is first passed through the dialyzer and then through the perfusion device. The problem with this treatment mode is that since the blood passes through the dialyzer and the perfusion device independently, only one treatment can be performed when the blood flows through one device, and the serial combination of the two devices in order to obtain two therapeutic effects increases the The volume of the blood chamber of the whole treatment device increases the amount of blood drawn from the patient's body and increases the risk of treatment.
目前已有相关专利提出将透析器与灌流器联接成一个整体的技术，但此类技术均为通过将透析器与灌流器简单的串联或拼接而成，实质上在治疗过程中，透析器与灌流器仍然是各自独立发挥治疗作用，与通过管路连接独立透析器与灌流器后进行组合治疗的模式并未有本质区别，也并未解决同时进行两种治疗模式导致患者体外引血量增加的问题。At present, relevant patents have proposed the technology of connecting the dialyzer and the perfusion device as a whole, but these technologies are all formed by simply connecting the dialyzer and the perfusion device in series or splicing. The perfusion devices still play their therapeutic roles independently, and there is no essential difference from the mode of combined treatment after connecting an independent dialyzer and perfusion device through pipelines, and it does not solve the problem that the two treatment modes at the same time lead to an increase in the amount of blood drawn outside the patient's body The problem.
实用新型内容Utility model content
本实用新型所要解决的技术问题在于针对现有技术的上述缺陷，提供一种可同步实现透析与灌流治疗的血液净化装置。The technical problem to be solved by the utility model is to provide a blood purification device that can simultaneously realize dialysis and perfusion treatment in view of the above-mentioned defects of the prior art.
为解决上述技术问题，本实用新型采用了以下的技术方案：设计一种可同步实现透析与灌流治疗的血液净化装置，包括外罐体和分别设于该外罐体两端的血液流入端和血液流出端，所述外罐体内部设有包含入口端和出口端的灌流单元，所述入口端与所述血液流入端相连通，所述出口端与所述血液流出端相连通；所述外罐体还设有与透析液管路连接的透析液进端口和透析液出端口，所述透析液进端口和透析液出端口与位于所述外罐体内部的透析液腔相连通；所述灌流单元包括带孔内罐体、透析膜层和吸附剂，所述吸附剂填充于所述带孔内罐体内，所述透析膜层附着于所述带孔内罐体上。In order to solve the above technical problems, the utility model adopts the following technical solutions: design a blood purification device that can simultaneously realize dialysis and perfusion treatment, including an outer tank body and blood inflow ports and blood Outflow end, the inside of the outer tank is provided with a perfusion unit including an inlet end and an outlet end, the inlet end communicates with the blood inflow end, and the outlet end communicates with the blood outflow end; the outer tank The body is also provided with a dialysate inlet port and a dialysate outlet port connected with the dialysate pipeline, and the dialysate inlet port and the dialysate outlet port are connected with the dialysate chamber located inside the outer tank body; the perfusion The unit includes an inner tank body with holes, a dialysis membrane layer and an adsorbent, the adsorbent is filled in the inner tank body with holes, and the dialysis membrane layer is attached to the inner tank body with holes.
与现有技术相比，本实用新型的血液净化装置可同步实现透析与灌流治疗，血液在通过该净化装置时能同时进行透析和灌流两种治疗，可以在保持一种治疗模式体外引血量不变的同时达到两种治疗的效果，同时可简化整个治疗体系管路连接等操作的复杂程度。Compared with the prior art, the blood purification device of the present utility model can simultaneously realize dialysis and perfusion treatment. When the blood passes through the purification device, both dialysis and perfusion treatments can be performed at the same time, and the amount of blood drawn outside the body can be kept in one treatment mode. The effect of two kinds of treatment can be achieved at the same time without change, and the complexity of the operation such as pipeline connection of the whole treatment system can be simplified at the same time.
在一种实施方式中，所述透析膜层包覆于所述带孔内罐体的外侧，所述透析液腔位于所述外罐体与所述透析膜层之间。In one embodiment, the dialysis membrane layer is coated on the outside of the inner tank with holes, and the dialysate cavity is located between the outer tank and the dialysis membrane layer.
在另一种实施方式中，所述透析膜层附着于所述带孔内罐体的内侧，所述吸附剂位于所述透析膜层的内侧。In another embodiment, the dialysis membrane layer is attached to the inner side of the perforated inner tank, and the adsorbent is located on the inner side of the dialysis membrane layer.
优选地，所述灌流单元的数量为大于或等于两个。Preferably, the number of the perfusion units is greater than or equal to two.
优选地，所述带孔内罐体的横截面直径为5mm～50mm，纵向长度为150～300mm。Preferably, the cross-sectional diameter of the inner tank body with holes is 5mm-50mm, and the longitudinal length is 150-300mm.
优选地，所述透析膜层为褶皱式膜层或卷曲式膜层。Preferably, the dialysis membrane layer is a pleated membrane layer or a coiled membrane layer.
进一步地，所述入口端与所述血液流入端之间以及所述出口端与所述血液流出端之间分别设有过滤网架。Further, a filter frame is respectively provided between the inlet port and the blood inflow port and between the outlet port and the blood outflow port.
进一步地，所述过滤网架与所述透析液腔之间设有密封胶层。Further, a sealant layer is provided between the filter frame and the dialysate cavity.
优选地，所述吸附剂为吸附树脂或活性炭。Preferably, the adsorbent is an adsorption resin or activated carbon.
优选地，所述透析膜层为聚砜、聚醚砜、聚丙烯或聚乙烯材质。Preferably, the dialysis membrane layer is made of polysulfone, polyethersulfone, polypropylene or polyethylene.
附图说明Description of drawings
图1是本实用新型的一种血液净化装置的纵向剖视图。Fig. 1 is a longitudinal sectional view of a blood purification device of the present invention.
图2是图1所示血液净化装置的A-A剖视图。Fig. 2 is an A-A sectional view of the blood purification device shown in Fig. 1 .
图3是图1所示血液净化装置的临床治疗模式示意图。Fig. 3 is a schematic diagram of the clinical treatment mode of the blood purification device shown in Fig. 1 .
具体实施方式Detailed ways
下面将详细描述本实用新型的各种实施方式，其中的实施例结合附图进行说明并在下文中描述。尽管本实用新型将结合示例性实施方式进行说明，应当理解本实用新型不限于这些示例性实施方式。相反，本实用新型不仅包括这些实施方式，而且还包括各种变形、改进。Various implementations of the present utility model will be described in detail below, and the embodiments thereof are described in conjunction with the accompanying drawings and described below. Although the invention will be described in conjunction with exemplary embodiments, it should be understood that the invention is not limited to these exemplary embodiments. On the contrary, this invention includes not only these embodiment but also various deformation|transformation and improvement.
图1所示为本实用新型的一种可同步实现透析与灌流治疗的血液净化装置18，该血液净化装置18包括外罐体9和分别设于该外罐体9两端的血液流入端10和血液流出端11，其中，血液流入端10、血液流出端11分别与外罐体9的端部形成螺纹连接，在血液流入端10、血液流出端11与外罐体9的连接部位分别设有密封圈5。所述密封圈5使外罐体9分别于血液流入端10和血液流出端11密闭配合，避免泄露而导致医疗风险或事故。同时，外罐体9还设有与图3所示的透析液管路连接的透析液进端口13和透析液出端口12。血液流入端10和血液流出端11分别由血液端口密封盖帽1所密封，透析液进端口13和透析液出端口12分别由透析液端口密封盖帽2所密封。Fig. 1 shows a kind of blood purification device 18 that can realize dialysis and perfusion treatment synchronously of the present utility model, and this blood purification device 18 comprises outer tank body 9 and the blood inflow port 10 that is respectively arranged at the two ends of this outer tank body 9 and Blood outflow end 11, wherein, blood inflow end 10, blood outflow end 11 form screw connection with the end of outer tank body 9 respectively; sealing ring 5. The sealing ring 5 makes the outer tank body 9 fit tightly with the blood inflow end 10 and the blood outflow end 11 respectively, so as to avoid medical risks or accidents caused by leakage. Meanwhile, the outer tank body 9 is also provided with a dialysate inlet port 13 and a dialysate outlet port 12 connected to the dialysate pipeline shown in FIG. 3 . The blood inflow port 10 and the blood outflow port 11 are respectively sealed by the blood port sealing cap 1 , and the dialysate inlet port 13 and the dialysate outlet port 12 are respectively sealed by the dialysate port sealing cap 2 .
所述外罐体9内部设有多个灌流单元20，本实施例中灌流单元20的数量为两个，每个灌流单元20包括了带孔内罐体8和透析膜层6，所述透析膜层6可设置于带孔内罐体8的内侧或外侧。所述灌流单元20还包括吸附剂7。当透析膜层6设置于带孔内罐体8的内侧时，吸附剂7填充于透析膜层6内侧，带孔内罐体8用于支撑透析膜层6，透析膜层6用于将血液和吸附剂7与透析液分离。当透析膜层6设置于带孔内罐体8的外侧时，吸附剂7填充于带孔内罐体8内部，带孔内罐体8支撑透析膜层6的同时使吸附剂7和透析膜层6分开，从而避免吸附剂7对透析膜层6的冲击而导致透析膜层6的破损，提高治疗装置的安全性。本实施例优选带孔内罐体8内部填充吸附剂7，透析膜层6设置于带孔内罐体8外侧的设计方案。所述透析膜层6可选用聚砜、聚醚砜、聚丙烯、聚乙烯等材质。透析液腔14位于外罐体9与透析膜层6之间。为增大外罐体9内部透析膜层的膜面积，可以增加灌流单元的数量，例如为20个甚至更多；同时将透析膜层6设置成褶皱式膜层或卷曲式膜层，从而使透析液与血液之间有足够大的接触面积，确保透析治疗效果。The outer tank body 9 is provided with a plurality of perfusion units 20. In this embodiment, the number of perfusion units 20 is two, and each perfusion unit 20 includes a perforated inner tank body 8 and a dialysis membrane layer 6. The dialysis The film layer 6 can be arranged on the inner side or the outer side of the perforated inner tank body 8 . The perfusion unit 20 also includes an adsorbent 7 . When the dialysis membrane layer 6 is arranged on the inner side of the tank body 8 with holes, the adsorbent 7 is filled in the inside of the dialysis membrane layer 6, and the inner tank body 8 with holes is used to support the dialysis membrane layer 6, and the dialysis membrane layer 6 is used for the blood And the adsorbent 7 is separated from the dialysate. When the dialysis membrane layer 6 is arranged on the outside of the inner tank body 8 with holes, the adsorbent 7 is filled inside the inner tank body 8 with holes, and the inner tank body 8 with holes supports the dialysis membrane layer 6 so that the adsorbent 7 and the dialysis membrane The layers 6 are separated, thereby avoiding the damage of the dialysis membrane layer 6 caused by the impact of the adsorbent 7 on the dialysis membrane layer 6, thereby improving the safety of the treatment device. In this embodiment, the interior of the inner tank body 8 with holes is preferably filled with the adsorbent 7 , and the dialysis membrane layer 6 is arranged outside the inner tank body 8 with holes. The dialysis membrane layer 6 can be made of materials such as polysulfone, polyethersulfone, polypropylene, and polyethylene. The dialysate chamber 14 is located between the outer tank body 9 and the dialysate membrane layer 6 . In order to increase the membrane area of the dialysis membrane layer inside the outer tank body 9, the number of perfusion units can be increased, such as 20 or even more; at the same time, the dialysis membrane layer 6 is set as a folded membrane layer or a curled membrane layer, so that There is a large enough contact area between the dialysate and the blood to ensure the effect of dialysis treatment.
每个灌流单元均包含入口端和出口端，其入口端与血液流入端10相连通，出口端与血液流出端11相连通。灌流单元的入口端与血液流入端10之间以及出口端与血液流出端11之间分别设有过滤网架3，而过滤网架3与透析液腔14之间则设有密封胶层4。所述密封胶层4将外罐体9与灌流单元20之间的空间密封，从而外罐体9与透析膜6之间形成一个透析液存储及流动的透析液腔14，避免血液进入透析液腔而导致医疗风险；透析液进端口13、透析液出端口12与透析液腔14连通。过滤网架3则避免灌流单元20中的吸附剂或者吸附剂掉落颗粒进入人体，从而确保安全。吸附剂7可为吸附树脂、活性炭等常见的吸附剂，优选为吸附树脂，根据所填充的吸附树脂种类的不同，本血液净化装置可实现不同的功能：如填充吸附尿毒症类毒物吸附树脂，则可实现同时对尿毒症患者血液进行透析及灌流治疗；如填充中毒毒物类吸附树脂，则可同时对中毒患者血液进行透析及吸附两种治疗中毒的疗法，更有效及全面的吸附各类不同分子量毒物。Each perfusion unit includes an inlet port and an outlet port, the inlet port communicates with the blood inflow port 10 , and the outlet port communicates with the blood outflow port 11 . Between the inlet port and the blood inflow port 10 and between the outlet port and the blood outflow port 11 of the perfusion unit are respectively provided filter frames 3 , and a sealant layer 4 is provided between the filter frame 3 and the dialysate chamber 14 . The sealant layer 4 seals the space between the outer tank body 9 and the perfusion unit 20, so that a dialysate cavity 14 for storing and flowing the dialysate is formed between the outer tank body 9 and the dialysis membrane 6, preventing blood from entering the dialysate The cavity causes medical risks; the dialysate inlet port 13 and the dialysate outlet port 12 communicate with the dialysate chamber 14 . The filter frame 3 prevents the adsorbent in the perfusion unit 20 or particles falling from the adsorbent from entering the human body, thereby ensuring safety. The adsorbent 7 can be common adsorbents such as adsorbent resin and activated carbon, preferably adsorbent resin. According to the different types of adsorbent resins filled, the blood purification device can realize different functions: such as filling and adsorbing uremic poisons with adsorbent resin, It can realize dialysis and perfusion treatment on the blood of uremia patients at the same time; if it is filled with poisonous adsorption resin, it can simultaneously perform dialysis and adsorption on the blood of poisoning patients to treat poisoning, which is more effective and comprehensive. molecular weight poison.
带孔内罐体8的横截面直径优选为5mm～50mm，例如为20mm；带孔内罐体8的纵向长度优选为150～300mm，例如为200mm。The cross-sectional diameter of the inner tank body 8 with holes is preferably 5 mm to 50 mm, for example 20 mm; the longitudinal length of the inner tank body 8 with holes is preferably 150 mm to 300 mm, for example 200 mm.
在上述血液净化装置18的制造过程中，将透析膜层6包覆在带孔内罐体8外表面后，采用透析器或血浆分离器的封胶工艺，使用医用聚氨酯AB胶等血液净化行业常用胶将包覆有透析膜层6的带孔内罐体8两端与外罐体9两端密封连接在一起，从而在透析膜层6内外侧形成不同的空腔，一个为外罐体9与透析膜层6之间的透析液腔14，一个为透析膜层6卷曲包裹所形成的透析膜层内腔。完成封胶后在外罐体9的一端装上过滤网架3及密封圈5，然后旋紧血液流出端11及其血液端口密封盖帽1，即可往带孔内罐体8内填充吸附树脂。吸附树脂填充完后安装上另一端的过滤网架3及密封圈5，然后旋紧血液流入端10及其血液端口密封盖帽1，即制得上述结构的血液净化装置。In the manufacturing process of the above-mentioned blood purification device 18, after the dialysis membrane layer 6 is coated on the outer surface of the inner tank body 8 with holes, the sealing process of the dialyzer or plasma separator is adopted, and the blood purification industry such as medical polyurethane AB glue is used. The two ends of the perforated inner tank body 8 covered with the dialysis membrane layer 6 are sealed and connected with the two ends of the outer tank body 9 by commonly used glue, so that different cavities are formed on the inside and outside of the dialysis membrane layer 6, and one is the outer tank body. The dialysate chamber 14 between 9 and the dialysate membrane layer 6 is a dialysate membrane layer inner cavity formed by wrapping the dialysate membrane layer 6 by crimping. After the sealing is completed, install the filter frame 3 and the sealing ring 5 on one end of the outer tank body 9, then tighten the blood outflow end 11 and the blood port sealing cap 1, and then the inner tank body 8 with holes can be filled with adsorption resin. After the adsorption resin is filled, install the filter frame 3 and the sealing ring 5 at the other end, and then tighten the blood inflow end 10 and the blood port sealing cap 1, and the blood purification device with the above structure is obtained.
在临床治疗过程中，本血液净化装置18的血液流入端10和血液流出端11分别连接动脉管15和静脉管16，侧面的透析液进端口13和透析液出端口12连接透析液管路。见图3，透析液管路当中设有透析液容器17和透析液泵19，透析液容器17当中的透析液在透析液泵19的驱动下沿管道21流动，当透析液从透析液进端口13进入透析液腔14，同时血液从血液流入端10进入填充有吸附树脂的透析膜层内腔，则此时对于透析膜层6而言，血液从内侧流过，透析液从外侧流过，此时即可对血液同时实现透析及灌流两种治疗。During clinical treatment, the blood inflow port 10 and the blood outflow port 11 of the blood purification device 18 are connected to the arterial tube 15 and the venous tube 16 respectively, and the dialysate inlet port 13 and the dialysate outlet port 12 on the side are connected to the dialysate pipeline. As shown in Fig. 3, a dialysate container 17 and a dialysate pump 19 are arranged in the middle of the dialysate pipeline, and the dialysate in the dialysate container 17 flows along the pipeline 21 under the drive of the dialysate pump 19, when the dialysate enters the port from the dialysate 13 enters the dialysate cavity 14, and at the same time blood enters the inner chamber of the dialysis membrane layer filled with adsorbent resin from the blood inflow end 10, then for the dialysis membrane layer 6 at this time, the blood flows from the inside and the dialysate flows from the outside, At this time, two treatments of dialysis and perfusion can be realized simultaneously for the blood.
由上述实施例可见，本实用新型的血液净化装置可同步实现透析与灌流治疗，血液在通过该净化装置时能同时进行透析和灌流两种治疗，可以在保持一种治疗模式体外引血量不变的同时达到两种治疗的效果，同时可简化整个治疗体系管路连接等操作的复杂程度。It can be seen from the above-mentioned embodiments that the blood purification device of the present invention can simultaneously realize dialysis and perfusion treatment. When blood passes through the purification device, both dialysis and perfusion treatments can be performed at the same time. It can achieve the effect of two kinds of treatment at the same time, and at the same time, it can simplify the complexity of the whole treatment system pipeline connection and other operations.
以上所述的仅是本实用新型的优选实施方式，应当指出，对于本领域的普通技术人员来说，在不脱离本实用新型发明构思的前提下，还可以做出若干变形和改进，这些都属于本实用新型的保护范围。What is described above is only the preferred embodiment of the utility model, it should be pointed out that for those of ordinary skill in the art, without departing from the premise of the utility model inventive concept, some deformations and improvements can also be made, and these are all Belong to the protection scope of the utility model.
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Cited By (11)
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| CN105107044A (en) * | 2015-09-02 | 2015-12-02 | 珠海健帆生物科技股份有限公司 | Blood purifier |
| CN105343954A (en) * | 2015-09-25 | 2016-02-24 | 珠海健帆生物科技股份有限公司 | Composite blood purifying device and manufacturing method thereof |
| CN105457118A (en) * | 2015-12-17 | 2016-04-06 | 珠海健帆生物科技股份有限公司 | Blood purifying apparatus and blood purifying system |
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| CN108245723A (en) * | 2016-12-28 | 2018-07-06 | 于杰 | Integrated blood purification |
| WO2018126333A1 (en) * | 2017-01-03 | 2018-07-12 | 于杰 | Integrated blood purifier |
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| WO2018126333A1 (en) * | 2017-01-03 | 2018-07-12 | 于杰 | Integrated blood purifier |
| CN107050545A (en) * | 2017-01-16 | 2017-08-18 | 东华大学 | The board-like haemodialyser of one kind stacking |
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| CN108744100A (en) * | 2018-06-20 | 2018-11-06 | 无锡市人民医院 | A hemodialysis device with backwashing function and backwashing method thereof |
| CN109758631A (en) * | 2019-01-28 | 2019-05-17 | 江苏关怀医疗科技有限公司 | A kind of absorption type haemodialyser |
| CN111202880A (en) * | 2020-02-03 | 2020-05-29 | 深圳汉诺医疗科技有限公司 | Purifying column, device and method for purifying blood |
| CN111359042A (en) * | 2020-03-18 | 2020-07-03 | 江西洪达医疗器械集团有限公司 | Hollow fiber hemodialyzer |
| CN112451772A (en) * | 2020-12-21 | 2021-03-09 | 南通大学附属医院 | But real-time supervision's blood purification device |
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