CN105457118A - Blood purifying apparatus and blood purifying system - Google Patents
Blood purifying apparatus and blood purifying system Download PDFInfo
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- CN105457118A CN105457118A CN201510956641.9A CN201510956641A CN105457118A CN 105457118 A CN105457118 A CN 105457118A CN 201510956641 A CN201510956641 A CN 201510956641A CN 105457118 A CN105457118 A CN 105457118A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
- A61M1/1623—Disposition or location of membranes relative to fluids
- A61M1/1627—Dialyser of the inside perfusion type, i.e. blood flow inside hollow membrane fibres or tubes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3672—Means preventing coagulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3687—Chemical treatment
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- Heart & Thoracic Surgery (AREA)
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- Urology & Nephrology (AREA)
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Abstract
The invention provides a blood purifying apparatus and a blood purifying system established based on the blood purifying apparatus, and belongs to the field of medical apparatuses. The blood purifying apparatus comprises a perfusion unit, a dialysis unit, a connection unit and a control unit. The perfusion unit comprises a perfusion chamber, and the inlet of the perfusion chamber is the artery port of the blood purifying apparatus. The dialysis unit comprises a dialysis chamber, and the outlet of the dialysis chamber is a vein port of the blood purifying apparatus. The connection unit comprises a housing and a separator plate; the space surrounded by the housing is divided into a first chamber and a second chamber which are mutually independent; the first chamber is the perfusion chamber; and the second chamber is the dialysis chamber. A dialysate inlet and a dialysate outlet are arranged in the side wall of the dialysis chamber in the housing. The control unit comprises a control switch and an external connection port. The control switch is used for selectively connect any two of the outlet of the perfusion chamber, the inlet of the dialysis chamber and the external connection port. According to the invention, the safety and the operation convenience for blood purifying treatment are improved.
Description
Technical field
The present invention relates to medical instruments field, specifically, the blood purification system relating to a kind of apparatus for purifying blood and build with this apparatus for purifying blood.
Background technology
Combined artificial kidney is the apparatus for purifying blood that hemoperfusion (HP) is combined in a kind of hemodialysis (HD), it makes full use of the advantage of hemoperfusion and hemodialysis, there is the advantages such as good biocompatibility, untoward reaction is few, the blood purification time is short, and metabolite, poisonous substance, the virulence factor of end stagerenaldisease can be removed comprehensively, and regulate water in blood, electrolyte balance, can prevention and therapy long-term dialysis complication, improve patients ' life quality, be clinical in the therapeutic scheme extensively promoted.
The blood purification system of existing combined artificial kidney composition comprises extracorporeal circulation pipeline and is connected to the apparatus for purifying blood in extracorporeal circulation pipeline, and extracorporeal circulation pipeline comprises blood circuit arterial line and blood circuit venous line.As shown in Figure 1, blood circuit arterial line is provided with the arterial end 01, pump line 02, tremulous pulse kettle 03 and the rear port 06 that are connected by transducer potector successively in direction of flow of blood; Pump line 02 is embedded in blood pump, is the blood flow providing source power in pump line 02; Tremulous pulse kettle 03 is provided with tremulous pulse kettle side pipe 04, and tremulous pulse kettle side pipe 04 is provided with stop valve; Transducer potector between tremulous pulse kettle 03 and rear port 06 is provided with stop valve 05.Blood circuit venous line is provided with the front port 013, venous chambers 014 and the vein end 016 that are connected by transducer potector successively in direction of flow of blood, and venous chambers 014 is provided with venous chambers side pipe 015, and venous chambers side pipe 015 is provided with stop valve.Apparatus for purifying blood comprises intermediate duct and the perfusion device 07 that connected by intermediate duct and dialyser 012, intermediate duct is provided with the front port 09 and rear port 011 that are connected by transducer potector 08 successively in direction of flow of blood, transducer potector 08 is provided with stop valve 010, front port 09 is connected with the vein port of perfusion device 07, and rear port 011 is connected with the tremulous pulse port of dialyser 012; The tremulous pulse port of perfusion device 07 forms the tremulous pulse port of apparatus for purifying blood, and the vein port of dialyser 012 forms the vein port of apparatus for purifying blood; The inner chamber of perfusion device 07 is perfusion chamber, and perfusion chamber is provided with the filter screen for preventing adsorbent from flowing out perfusion chamber at its two ends place; The inner chamber of dialyser 012 is dialysis chamber, and dialysis chamber is built-in with dialyzer, and the two ends of dialyzer are respectively provided with adhesive-layer.The rear port 06 of blood circuit arterial line is connected with the tremulous pulse port of apparatus for purifying blood, and the front port 013 of blood circuit venous line is connected with the vein port of apparatus for purifying blood.
The clinical treatment mode of this blood purification system is that first hemodialysis (HD) is combined hemoperfusion (HP) and treated 2 hours, carry out separately hemodialysis 2 hours again, by the work of blood pump 02, arterial blood is extracted out through perfusion device 07 and dialyser 011 or the purification only through dialyser 011 after being removed by perfusion device 07, again through blood circuit venous line, by through detoxification, anhydrate, electrolyte exchange after in the defeated the Huis' body of blood that purified, temporarily play the effect of alternative human kidney function.
In the process of whole blood purification treatment, there is following inconvenience or risk: (1), when misoperation, the intermediate duct be connected between dialyser with perfusion device there will be situation about being connected loosely, occur coming off in therapeutic alliance process and cause blood loss, and also there is unhandy problem in intermediate duct connection; (2) time, in order to avoid rushing in advance, in perfusion device, adsorbent fragment pollutes the dialyzer in dialyser or destroys, need dismantle connecting line, perfusion device, dialyser, the operation such as refitting, increase the complicated operation degree of medical personnel, exist simultaneously and cause antibacterial, virus etc. in air to invade the risk in blood purification system, negative effect is caused to the safety and efficacy for the treatment of; (3), after completing therapeutic alliance, first need remove perfusion device, then dialyser is exhausted and could be used, not only complex operation, and there is potential safety hazard; (4) the long blood chamber vol increased outside patient body of extracorporeal circulation pipeline, increases the risk that patient produces the complication such as hypotension.
Summary of the invention
Main purpose of the present invention is to provide a kind of easy to operate and apparatus for purifying blood that safety is high;
Another object of the present invention is to provide the blood purification system that more than one state apparatus for purifying blood structure.
In order to realize above-mentioned main purpose, apparatus for purifying blood provided by the invention comprises perfusion unit, unit with dialysis, linkage unit and control unit.Perfusion unit comprises perfusion chamber, and the import of perfusion chamber is the tremulous pulse port of apparatus for purifying blood.Unit with dialysis comprises dialysis chamber, and the outlet of dialysis chamber is the vein port of apparatus for purifying blood.Linkage unit comprises shell and dividing plate, and the chamber that shell surrounds by dividing plate is separated into the first separate chamber and the second chamber, and the first chamber is perfusion chamber, and the second chamber is dialysis chamber.Shell is provided with dialysis solution import and dialysis solution outlet in the side-walls of dialysis chamber.Control unit comprises gauge tap and outer even port, and gauge tap is used for being communicated with the two in the outlet of perfusion chamber, the import of dialysis chamber and outer connectivity port selectively.
From above scheme, whole apparatus for purifying blood integrally, possesses hemoperfusion and hemodialysis function simultaneously, can provide better blood purification treatment for patient.By with the connection of body circulation line after, breaking through in journey without the need to carrying out pipeline dismounting and refitting in advance, just can realize rushing in advance separately dialysis chamber and perfusion chamber, while simplifying the operation, raising safety in utilization; And after therapeutic alliance, without the need under the condition of detaching pipelines, independent dialysis treatment can be switched to, improve the safety for the treatment of.Pass through regulation control switch, by the inner chamber environment of perfusion chamber and the inner chamber environment of dialysis chamber mutually isolated, the adsorbent fragment that may exist in perfusion chamber is avoided to enter in dialysis chamber, the dialysis function of dialyzer is impacted, by dialyzer and the different requirements of adsorbent to storage environment humidity, dry wet preservation can be realized accordingly simultaneously.
Concrete scheme is that shell comprises cylindrical shell, is fastened on the first end cap on the port of this cylindrical shell first axial end, and is fastened on the second end cap on the port of its second axial end; Axial arranged along cylindrical shell of dividing plate; The first end cap position corresponding with dividing plate is provided with the installing hole for installing gauge tap, position corresponding with installing hole on dividing plate is provided with the mount pad for installing gauge tap, and the outlet of perfusion chamber and the import of dialysis chamber are positioned at by the side of mount pad accordingly; Tremulous pulse port is located at position corresponding with perfusion chamber on the end wall of the second end cap, and vein port is located at position corresponding with dialysis chamber on the end wall of the second end cap; Dialysis solution import and dialysis solution outlet are located on the sidewall of cylindrical shell.Structure is simple, is convenient to assembling.
Scheme is that dividing plate comprises central dividing plate, the first dividing plate and second partition more specifically; First end covers the first container cavity of the axial open at one end be provided with at the first end cap, and the second end cap is provided with at the second uncovered container cavity of the axial Single port of the second end cap; Central dividing plate and cylindrical shell are made in integrated mode, and the chamber of cylindrical shell is separated into left chamber and right chamber; First dividing plate and the first end cap are made in integrated mode, and the first container cavity are separated into the first left container cavity and the first right container cavity; Second partition and the second end cap are made in integrated mode, and the second container cavity are separated into the second left container cavity and the second right container cavity; Left chamber, the first left container cavity and the second left container cavity docking form perfusion chamber, and right chamber, the first right container cavity and the second right container cavity docking form dialysis chamber; Mount pad is located on the first dividing plate.Be convenient to manufacture and assembling.
A concrete again scheme is that the internal face of left chamber near the end of the first end cap is provided with the shaft shoulder in first, and the internal face near the end of the second end cap is provided with the shaft shoulder in second; Be pressed with the port of export filter screen of perfusion unit in the end face of the first end cap and first between the shaft shoulder, in the end face of the second end cap and second, between the shaft shoulder, be pressed with the entrance point filter screen of perfusion unit; Also comprise the first sealing gasket and the second sealing gasket, the first sealing gasket comprises the first connected O-ring seal portion and the first strip diaphragm seal portion; Second sealing gasket comprises the second connected O-ring seal portion and the second strip diaphragm seal portion; First O-ring seal portion is pressed between the end face of the first end cap and the end face of the first axial end, between the end face that the first strip diaphragm seal portion is pressed on the first dividing plate and the end face of central dividing plate; Second O-ring seal portion is pressed between the end face of the second end cap and the end face of the second axial end, and the second strip diaphragm seal portion is pressed between the end face of second partition and the end face of central dividing plate.
Another concrete scheme is the first bulge loop that the first end cap end face outer rim convexes to form that plural first pre-determined bit is protruding and be positioned at inside this first pre-determined bit projection, and on the first axial end end face, indent is formed with the first pre-determined bit groove matched with the first pre-determined bit projection and the first groove matched with the first bulge loop.Second end cap end face outer rim convexes to form the second bulge loop that plural second pre-determined bit is protruding and be positioned at inside this second pre-determined bit projection, and on the second axial end end face, indent is formed with the second pre-determined bit groove matched with the second pre-determined bit projection and the second groove matched with the second bulge loop.First pre-determined bit projection is fixedly connected with for permanent type buckle draw-in groove with between the first pre-determined bit groove, being adhesively fixed is connected or is welded and fixed connection, and the second pre-determined bit projection is fixedly connected with for permanent type buckle draw-in groove with between the second pre-determined bit groove, being adhesively fixed is connected or is welded and fixed connection.Be convenient to location between end cap with cylindrical shell and be fixedly connected with, improve the anti-identification opened simultaneously.
Preferred scheme is the pedestal that gauge tap comprises inner cylinder, outer cylinder and is arranged on mount pad, and mount pad is located on dividing plate.It is outer and be sealed and matched with inner cylinder that outer cylinder can be placed on inner cylinder rotatably around own axes; Pedestal is provided with installation circular hole, and inner cylinder blind end is fixedly connected with the bottom surface of installing circular hole, and outer cylinder one end is placed in the interior also opposite base of installation circular hole and can rotates around own axes, for being sealed and matched between the outside wall surface of outer cylinder and the internal face of installation circular hole.Pedestal is provided with the first through hole of being communicated with perfusion chamber outlet and the second through hole with dialysis chamber inlet communication, and position corresponding with the first through hole on inner cylinder barrel is provided with third through-hole and the position corresponding with the second through hole is provided with fourth hole; The barrel of outer cylinder is provided with plural intercommunicating pore; Outer cylinder rotates around own axes, and intercommunicating pore is only communicated with the first through hole and third through-hole selectively, or is only communicated with the second through hole and fourth hole, or is communicated with the first through hole and third through-hole and the second through hole and fourth hole simultaneously; Inner cylinder is outer even port away from the port of blind end.
Preferred scheme is the first through hole, the second through hole, third through-hole and fourth hole coaxial line and this axis is mutually orthogonal with the plate face of dividing plate; Intercommunicating pore comprises the first intercommunicating pore, the second intercommunicating pore and third connecting hole; First intercommunicating pore and the second intercommunicating pore coaxial line and the axis in this axis and third connecting hole is mutually orthogonal.
Another preferred scheme is that outer cylinder can move along self axial reciprocating relative to inner cylinder; The outer tube wall of inner cylinder is provided with the spacing outer shaft shoulder, and the inner tube wall of outer cylinder is provided with the spacing interior shaft shoulder, and the spacing outer shaft shoulder and the spacing interior shaft shoulder are mutually against forming spacing away from pedestal of outer cylinder; Outer cylinder forms locating piece away from the outer head face hump connecting port, and the bottom surface of installation circular hole is formed with the locating slot matched with locating piece, and locating slot comprises the first locating slot, the second locating slot and the 3rd locating slot; Outer cylinder is greater than along self axially movable distance the greatest length that locating piece inserts locating slot; When locating piece is positioned at the first locating slot, intercommunicating pore is communicated with the first through hole and third through-hole and the second through hole and fourth hole simultaneously; When locating piece is positioned at the second locating slot, intercommunicating pore is only communicated with the first through hole and third through-hole; When locating piece is positioned at the 3rd locating slot, intercommunicating pore is only communicated with the second through hole and fourth hole.
In order to realize another object above-mentioned, blood purification system provided by the invention comprises extracorporeal circulation pipeline and is connected to the apparatus for purifying blood in this extracorporeal circulation pipeline.Wherein, the apparatus for purifying blood of apparatus for purifying blood described by above-mentioned arbitrary technical scheme.
Concrete scheme is that extracorporeal circulation pipeline comprises blood circuit arterial line, blood circuit venous line, the first threeway, the first tremulous pulse arm, the second tremulous pulse arm, the second threeway, intervalve, the 3rd threeway, the first vein arm and the second vein arm.The first interface of the first threeway is connected with the rear port of blood circuit arterial line, and the second interface is connected with the Single port of the first tremulous pulse arm, and the 3rd interface is connected with the Single port of the second tremulous pulse arm; The another port of the first tremulous pulse arm is connected with tremulous pulse port; The first interface of the second threeway is communicated with the another port of the second tremulous pulse arm, and the second interface is connected with the Single port of intervalve, and the 3rd interface is connected with the Single port of the second vein arm; The another port of intervalve is connected with the outer port that connects; The first interface of the 3rd threeway is connected with the another port of the second vein arm; Second interface is connected with the Single port of the first vein arm, and the 3rd interface is connected with the front port of blood circuit venous line; The another port of the second vein arm is connected with vein port; First tremulous pulse arm, the second tremulous pulse arm, intervalve, the first vein arm and the second vein arm are equipped with stop valve.
Accompanying drawing explanation
Fig. 1 is the extracorporeal circulation pipeline of existing blood purification system and the connection diagram of perfusion device and dialyser;
Fig. 2 is the structural representation of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Fig. 3 is A partial enlarged drawing in Fig. 2;
Fig. 4 is B partial enlarged drawing in Fig. 2;
Fig. 5 is C partial enlarged drawing in Fig. 2;
Fig. 6 is D partial enlarged drawing in Fig. 2;
Fig. 7 is the top view of the cylindrical shell of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Fig. 8 is the upward view of the first end cap of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Fig. 9 is the structural representation of the first sealing gasket of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Figure 10 is the top view of the second end cap of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Figure 11 is the structural representation of the second sealing gasket of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Figure 12 is the structural representation of the control unit of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Figure 13 is the top view of the control unit of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Figure 14 is the working state schematic representation of the gauge tap of apparatus for purifying blood in blood purification system first embodiment of the present invention;
Figure 15 is the connection diagram of pipeline and apparatus for purifying blood in blood purification system first embodiment of the present invention;
Figure 16 is the structural representation of the gauge tap of apparatus for purifying blood in blood purification system second embodiment of the present invention;
Figure 17 is the structural representation of apparatus for purifying blood in blood purification system of the present invention 3rd embodiment;
Figure 18 is the top view of the first end cap of apparatus for purifying blood in blood purification system of the present invention 3rd embodiment;
Figure 19 is the structural representation of gauge tap in blood purification system of the present invention 4th embodiment;
Figure 20 is the top view of the cylindrical shell of apparatus for purifying blood in blood purification system of the present invention 6th embodiment;
Figure 21 is the upward view of the first end cap of apparatus for purifying blood in blood purification system of the present invention 6th embodiment.
Below in conjunction with embodiment and accompanying drawing thereof, the invention will be further described.
Detailed description of the invention
The present invention mainly improves the structure of apparatus for purifying blood in blood purification system, relate to the structure of linkage unit between absorbing unit and filter element and control unit, while improving blood purification treatment safety, simplify the operating process of medical personnel, other part-structures of blood purification system design according to existing product.
Following embodiment, mainly for blood purification system of the present invention, because blood purification system of the present invention have employed apparatus for purifying blood of the present invention, has comprised the explanation to apparatus for purifying blood embodiment in the explanation of blood purification system embodiment.
Blood purification system first embodiment
Blood purification system is made up of apparatus for purifying blood, extracorporeal circulation pipeline and dialysis solution pipeline, and apparatus for purifying blood is made up of perfusion unit, unit with dialysis, linkage unit and control unit.Control unit is made up of gauge tap and the outer port that connects.
Linkage unit is made up of shell and dividing plate, and the inner chamber that shell surrounds by dividing plate is separated into the first separate chamber and the second chamber, and the first chamber is the perfusion chamber of perfusion unit, and the second chamber is the dialysis chamber of unit with dialysis.
See Fig. 2, shell, by cylindrical shell 11, is fastened on the first end cap 12 on the port of the first axial end of cylindrical shell 11, and be fastened on cylindrical shell 11 the second axial end port on the second end cap 13 form.Dividing plate is made up of central dividing plate 141, first dividing plate and second partition 143.
See Fig. 2 to Fig. 7, cylindrical shell 11 is a circular cylinder body, central dividing plate 141 and cylindrical shell 11 are made in integrated mode, the chamber of cylindrical shell 11 is separated into left chamber 111 and right chamber 112 along the axial arranged of cylindrical shell 11 by central dividing plate 141, parallels layout to make perfusion chamber with the axis of dialysis chamber.The side wall surface of left chamber 111 is the smooth and continuous curved surface be made up of arcwall face, avoids hemoperfusion process to form blood dead angle, to reduce blood coagulation risk.The inwall of the upper port of left chamber 111 is formed with the shaft shoulder 1111 in first, the internal face of lower port is formed with the shaft shoulder 1112 in second, in first, the shaft shoulder 1111 is equipped with port of export filter screen 151, in second, the shaft shoulder 1112 is equipped with entrance point filter screen 152, the section chambers of left inside chamber 111 between port of export filter screen 151 and entrance point filter screen 152 is configured for the container cavity holding adsorbent 1110.Adsorbent 1110 can be the combination of one or more in the blood-purifying adsorbing agents such as resin sorbent, acticarbon, natural macromolecule adsorbent.
Port of export filter screen 151 is made up of the rack 1511 be supported in first on the shaft shoulder 1111 and the mesh sheet 1512 be fixed on rack 1511 port, flow out from the upper port of left chamber 111 for preventing adsorbent 1110, entrance point filter screen 152 is made up of the rack 1521 be supported in second on the shaft shoulder 1112 and the mesh sheet 1522 that is fixed on rack 1521 port, flows out from the lower port of left chamber 111 for preventing adsorbent 1110.
It is dialyzer 1121 that the place of two-port up and down of right chamber 112 is provided with between the bonding glue-line 1120 of bonding glue-line 1120, two, and dialyzer 1121 can be the hemodialysis membrane of the materials such as polyether sulfone, polysulfones, polypropylene.
The barrel of cylindrical shell 11 is provided with dialysis solution import 104 and dialysis solution outlet 103 in the side-walls of right chamber 112, and dialysis solution import 104 is by dialysis solution import block 108 sealing, and dialysis solution outlet 103 exports block 107 by dialysis solution and seals.
See Fig. 2 to Fig. 8, the end face outer rim indent of the first axial end of cylindrical shell 11 is formed with two the first pre-determined bit grooves 113, the center line conllinear of two the first pre-determined bit grooves 113 and mutually vertical with the plate face of central dividing plate 121, the radial middle part indent of the first axial end end face is formed with the first groove 114 arranged with cylindrical shell 11 coaxial line.The position that the end face of the first end cap 12 is corresponding with the first pre-determined bit groove 113 has convexed to form the first pre-determined bit projection 123, and the position corresponding with the first groove 114 convexes to form the first bulge loop 124 matched with the first groove 114.The medial wall of the first pre-determined bit projection 123 is formed with buckle, the bottom surface 1131 of the first pre-determined bit groove 113 is formed with the draw-in groove matched with buckle.When on the first axial end that the first end cap 12 is fastened on cylindrical shell 11, by coordinating of the first bulge loop 124 and the first groove 114 and coordinating of the first pre-determined bit protruding 123 and the first pre-determined bit groove 113, realize the first end cap 12 and cylindrical shell 11 first axial end pre-determined bit diametrically, the mechanical seal simultaneously realized therebetween coordinates; Forming permanent type buckle draw-in groove by the buckle in the first pre-determined bit projection 123 and the draw-in groove on the first pre-determined bit groove 113 to be connected, is that the first end cap 12 realizes circumferential location with coordinating of cylindrical shell 11 first axial end, being fixedly connected with both simultaneously realizing.
First end cap 12 and the first dividing plate 142 are made in integrated mode, and the first end cap 12 is provided with the first container cavity of axially open at one end, the uncovered direction towards cylindrical shell 11 of the first container cavity.First container cavity is separated into the first left container cavity 121 and the first right container cavity 122 by the first dividing plate 142, the internal face of the first left container cavity 121 and the first right container cavity 122 is smooth continuous curve surface.
The radial central position of the first end cap 12 is formed with the installing hole 120 for installing gauge tap 17, on first dividing plate 142, the position corresponding with installing hole 120 is provided with the mount pad 1422 for installing gauge tap 17, and installing hole 120 is cross-shaped configuration with the cross section of mount pad 1422.First dividing plate 142 is formed with two positioning convex 1421 towards the head face hump of cylindrical shell 11, is positioned at mount pad 1422 both sides accordingly.
Sealed by the first sealing gasket 161 as shown in Figure 9 between the first axial end of the first end cap 12 and cylindrical shell 11, first sealing gasket 161 is made up of the first O-ring seal portion 1610 be connected and the first strip diaphragm seal portion 1611, and the first strip diaphragm seal portion 1611 is formed with two detents 1612 matched with positioning convex 1421 towards indent on the end face direction of cylindrical shell 11.First O-ring seal portion 1610 is pressed between the end face of the end face of the first end cap 12 and the first axial end of cylindrical shell 11, and the first strip diaphragm seal portion 1611 is pressed between the end face of the first dividing plate 142 and the end face of central dividing plate 141.
By coordinating of positioning convex 1421 and detent 1612, realize the quick position of the first sealing gasket 161 and fixedly mount fast.
See Fig. 2 to Fig. 6 and Figure 10, the end face outer rim indent of the second axial end of cylindrical shell 11 is formed with the second pre-determined bit groove 115, the center line conllinear of two pre-determined bit grooves 115 and mutually vertical with the plate face of central dividing plate 121, the radial middle part indent of the end face of the second axial end is formed with the second groove 116 arranged with cylindrical shell 11 coaxial line.The position that the end face of the second end cap 13 is corresponding with the second pre-determined bit groove 115 has convexed to form the second pre-determined bit projection 133, and the position corresponding with the second groove 116 convexes to form the second bulge loop 134 matched with the second groove 116.The medial wall of the second pre-determined bit projection 133 is formed with buckle, the bottom surface 1151 of the second pre-determined bit groove 115 is formed with the draw-in groove matched with buckle, when the second end cap 13 is fastened on the second axial end, by coordinating of the second bulge loop 134 and the second groove 116 and coordinating of the second pre-determined bit protruding 133 and the second pre-determined bit groove 115, realize the second end cap 13 and cylindrical shell 11 second axial end location diametrically, the mechanical seal simultaneously realized therebetween coordinates; Forming permanent type buckle draw-in groove by the buckle in the second pre-determined bit projection 133 and the draw-in groove on the second pre-determined bit groove 115 to be connected, is that the second end cap 13 realizes circumferential location with coordinating of the second axial end, being fixedly connected with both simultaneously realizing.
Second end cap 13 is made in integrated mode with second partition 143, and the second end cap 13 is provided with the second container cavity of axially open at one end, the uncovered direction towards cylindrical shell 11 of the second container cavity.The internal face that second container cavity is separated into the second left container cavity 131 and the left container cavity of the second right container cavity 132, second 131 and the second right container cavity 132 by second partition 143 is smooth continuous curve surface.
Second end cap 13 position corresponding with the second left container cavity 131 is provided with blood mouth as tremulous pulse port 101, i.e. the import of perfusion chamber, and tremulous pulse port 101 is sealed by arterial end lid cap 105; Second end cap 13 position corresponding with the second right container cavity 132 is provided with blood mouth as vein port 102, i.e. the outlet of dialysis chamber, and vein port 102 is sealed by vein end lid cap 106.Second partition 143 is formed with positioning convex 1431 towards the head face hump of cylindrical shell 11.
Pass through the second sealing gasket 162 as shown in figure 11 between the second axial end of the second end cap 13 and cylindrical shell 11 to seal, second sealing gasket 162 is made up of the second O-ring seal portion 1620 be connected and the second strip diaphragm seal portion 1621, and the second strip diaphragm seal portion 1621 is formed with towards indent on the end face direction of cylindrical shell 11 detent 1622 matched with positioning convex 1431.Second O-ring seal portion 1620 is pressed between the end face of the end face of the second end cap 13 and the second axial end of cylindrical shell 11, and the second strip diaphragm seal portion 1621 is pressed between the end face of second partition 143 and the end face of central dividing plate 141.
By coordinating of positioning convex 1431 and detent 1622, realize the quick position of the second sealing gasket 162 and fixedly mount fast.
When the first end cap 12 is fastened on the port of the first axial end of cylindrical shell 11, and the second end cap 13 is when being fastened on the port of the second axial end of cylindrical shell 11, first left container cavity 121, left chamber 111 and the second left container cavity 131 dock and form perfusion chamber, and the medial surface of perfusion chamber is a smooth continuous curve surface, reduce the risk occurring blood coagulation.First right container cavity 122, right chamber 112 and the second right container cavity 132 dock and form dialysis chamber, and the medial surface of dialysis chamber is a smooth continuous curve surface.
See Fig. 2, Figure 12, Figure 13 and Figure 14, gauge tap 17 is made up of pedestal 173, outer cylinder 172 and inner cylinder 171.
The lateral surface of pedestal 173 is the cross-shaped configuration matched with installing hole 120 and mount pad 1422, be convenient to location and circumference is fixing, and pedestal 173 is made up of elaxtic seal, when pedestal 173 being mounted in installing hole 120 and mount pad 1422, by welding or the mode such as bonding, make the side wall surface of pedestal 173 and installing hole 120 and mount pad 1422 for being sealedly and fixedly connected, pedestal 173 realizes being sealed and matched with the end face of central dividing plate 141 towards the end face of cylindrical shell 11 by the first strip diaphragm seal portion 1611 simultaneously, thus effectively keep the separate of perfusion chamber and dialysis chamber, namely gauge tap 17 can only be passed through between the two, tremulous pulse port 101 and vein port 102 are interconnected, when this three closes, perfusion chamber and dialysis chamber will keep mutually isolated.
The barrel 1710 of inner cylinder 171 is provided with blood mouth away from one end of pedestal 173 and connects port one 711 as the outer of the present embodiment, the outer port one 711 that connects connects port block 109 sealing by outer, barrel 1710 is blind end away from outer one end connecting port, the barrel of blind end is formed with third through-hole 1712 and fourth hole 1713, the outer tube wall of barrel 1710 is formed with the spacing outer shaft shoulder 1716 in the top of third through-hole 1712 and fourth hole 1713, and third through-hole 1712 and fourth hole 1713 coaxial line are arranged and the axis normal of this axis and inner cylinder 171.The head face hump of blind end is formed with positioning convex 1714.
The barrel 1720 of outer cylinder 172 has convexed to form knob 1721 away from one end outer wall of pedestal 173, the barrel position corresponding with the spacing outer shaft shoulder 1716, inner side is formed with the spacing interior shaft shoulder 1724 matched with the spacing outer shaft shoulder 1716, arrange and the axis normal of this axis and outer cylinder 172 away from the outer barrel connecting one end of port one 711 is formed with the first intercommunicating pore 1722, second intercommunicating pore 1723 and third connecting hole 1726, first intercommunicating pore 1722 and the second intercommunicating pore 1723 coaxial line.Barrel 1720 is formed with two pieces of locating convex blocks 1725 away from the head face hump of port one 711.
Pedestal 173 is provided with the installation circular hole 1731 be sealed and matched mutually with the outer peripheral face of outer cylinder 172, the side that pedestal 173 is corresponding with perfusion chamber is formed and is communicated with this side and the first through hole 1732 installing circular hole 1731, the side corresponding with dialysis chamber is formed with this side of connection to arrange with the second through hole 1733, first through hole 1731 and the second through hole 1733 coaxial line of installing circular hole 1731 and this axis and the axis normal installing circular hole 1731.The bottom surface indent of circular hole 1731 is installed and is formed with to match with positioning convex 1714 detent 1735 and three pairs of detents 1734 matching with locating convex block 1725.
By coordinating of positioning convex 1714 and detent 1735, realize the quick position of inner cylinder 171 and pedestal 173 and by the end face of inner cylinder 171 blind end and the bonding connection of installing between circular hole 1731 bottom surface, realize being fixedly connected with of inner cylinder 171 and pedestal 173.
Outer cylinder 172 opposite base 173 and inner cylinder 171 can rotate around own axes, can move along self axial reciprocating simultaneously.Outer cylinder 172 relatively inner cylinder 171 vertically moveable distance be greater than locating convex block 1725 and can insert greatest length in detent 1734, and it is axial in the direction moving process near port one 711 along self in outer cylinder 172, when the spacing interior shaft shoulder 1724 is against the spacing outer shaft shoulder 1716, locating convex block 1725 departs from the stop of detent 1734 to it, and outer cylinder 172 can be rotated around own axes.
When locating convex block 1725 is positioned at first pair of detent 1734, first intercommunicating pore 1722 is for being communicated with the first through hole 1732 and third through-hole 1712, second intercommunicating pore 1723 is for connecting the second through hole 1733 and fourth hole 1713, now, the outlet of perfusion chamber is by the first through hole 1732, first intercommunicating pore 1722, third through-hole 1712, the inner chamber 1715 of inner cylinder 171, fourth hole 1713, the inlet communication of the second intercommunicating pore 1723 and the second through hole 1733 and dialysis chamber, and the import of the outlet of perfusion chamber and dialysis chamber is all communicated with port one 711 by chamber 1715.
As shown in figure 14, when the relative inner cylinder of outer cylinder 172 is rotated counterclockwise 90 degree, locating convex block 1725 is positioned at second pair of detent 1734, third connecting hole 1726 is for connecting the first through hole 1732 and third through-hole 1712, now, perfusion chamber outlet is connected with port one 711 by the first through hole 1732, third connecting hole 1726, third through-hole 1712 and inner chamber 1715, and the import of dialysis chamber is in closed state.
When the relative inner cylinder of outer cylinder 172 continues to be rotated counterclockwise 180 degree, locating convex block 1725 is positioned at the 3rd pair of detent 1734, third connecting hole 1726 is for connecting the second through hole 1733 and fourth hole 1713, now, dialysis chamber import is connected with port one 711 by the second through hole 1733, third connecting hole 1726, fourth hole 1713 and inner chamber 1715, and the outlet of perfusion chamber is in closed state.
On the outer face of the first end cap 12, corresponding position is provided with the recognition marks corresponding with above-mentioned three kinds of states, and convenient operation personnel are to the operation of gauge tap 17.And after the switching of completion status, axially locating convex block 1725 is pressed in corresponding detent 1734 along outer cylinder 172, realize the locking of state.When needing to change connection status, need first outer cylinder 172 to be mentioned to carry out switching state again, effectively prevent unexpected touching and change connection status, the safety of blood purification treatment is impacted.
After the assembling completing apparatus for purifying blood 1, locating convex block 1725 is made to be positioned at second pair of detent 1734, block perfusion chamber outlet and being communicated with between dialysis chamber import, the hygrometric state that can realize perfusion chamber interior environment is preserved, and the environment of dialysis chamber is dry state preservation.
See Figure 15, extracorporeal circulation set tube route blood circuit arterial line 2, the threeway 44 of blood circuit venous line 3, first threeway 41, first tremulous pulse arm 42, second tremulous pulse arm 43, second, intermediate duct 45, the 3rd threeway 46, first vein arm 47, second vein arm 48 and be located at stop valve 421 on the first tremulous pulse arm 42, second tremulous pulse arm 43, intermediate duct 45, first vein arm 47, second vein arm 48 accordingly, stop valve 431, stop valve 451, stop valve 471, stop valve 481 form.
The rear port of blood circuit arterial line 2 is connected with the first interface of the first threeway 41, and the front port of blood circuit venous line 3 is connected with the 3rd interface of the 3rd threeway 46.
The Single port of the first tremulous pulse arm 42 is connected with the second interface of the first threeway 41, and another port is connected with the tremulous pulse port 101 of apparatus for purifying blood 1.
The Single port of the second tremulous pulse arm 43 is connected with the 3rd interface of the first threeway 41, and another port is connected with the first interface of the second threeway 44.
The Single port of intermediate duct 45 is connected with the second interface of the second threeway 44, another port with on gauge tap 17 the outer port one 711 that connects be connected.
The Single port of the first vein arm 47 is connected with the second interface of the 3rd threeway 46, and another port is connected with the vein port 102 of apparatus for purifying blood 1.
The Single port of the second vein arm 48 is connected with the 3rd interface of the second threeway 44, and another port is connected with the first interface of the 3rd threeway 46.
After connecting extracorporeal circulation pipeline, dialysis solution import 104 connects outer connecting leg 51 and connect outer connecting leg 52 in dialysis solution outlet 103.
Blood purification system is rushed in advance, breaks through journey in advance as follows:
(1) stop valve 421,451,481 is made to be in opening, stop valve 431,471 is in closed condition, locating convex block 1725 is positioned at second pair of detent 1734, rush liquid in advance to enter from blood circuit arterial line 2, by arranging in waste fluid bag after the first tremulous pulse arm 42, tremulous pulse port 101, perfusion chamber, inner chamber 1715, outer even port one 711, intervalve 45, second vein arm 48 and blood circuit venous line 3, pre-punching is separately carried out to perfusion chamber.
(2) stop valve 421,481 is closed, and open stop valve 431,471, locating convex block 1725 is positioned at the 3rd pair of detent 1734, rush liquid in advance to enter from blood circuit arterial line 2, by arranging in waste fluid bag after the second tremulous pulse arm 43, intervalve 45, outer even port one 711, inner chamber 1715, dialysis chamber, the first vein arm 47 and blood circuit venous line 3, pre-punching is separately carried out to dialysis chamber.
After completing pre-punching, dialysis solution import 104 is connected with dialysis solution source by outer connecting leg 51, and dialysis solution outlet 103 is connected with waste fluid bag by outer connecting leg 52.Therapeutic process is as follows:
(1) therapeutic alliance, make stop valve 431,451,481 be in closed condition, stop valve 421,471 is in opening, and locating convex block 1725 is positioned at first pair of detent 1734.Blood enters in perfusion chamber adsorb blood through blood circuit arterial line 2, first tremulous pulse arm 42, tremulous pulse port 101, entered in dialysis chamber by the blood after absorption by gauge tap 17, in dialysis chamber, blood is dialysed, after vein port 102, first vein arm 47 and blood circuit venous line 3, in defeated the Huis' body, after 2 hours, therapeutic alliance is completed by the blood after dialysis.
(2) independent dialysis treatment, make stop valve 421,481 be in closed condition, stop valve 431,451,471 is in opening, and locating convex block 1725 is positioned at the 3rd pair of detent 1734.Blood enters dialysis chamber dialyse separately to blood through blood circuit arterial line 2, second tremulous pulse arm 43, intermediate duct 45, inner chamber 1715, by the blood after dialysis by vein port 102, first vein arm 47 and the defeated the Huis' body of blood circuit venous line 3, after 2 hours, complete independent dialysis treatment.
When over the course for the treatment of, as burst perfusion unit or a unit with dialysis part abnormal, or need the instant treatment time regulating wherein a certain unit, or due to other reason need stop the treatment of a certain unit time, without the need to shutting down and taking depurator and pipeline apart.Such as, as needs stop perfusion treatment, retain dialysis treatment, make stop valve 421,481 be in closed condition, stop valve 431,451,471 is in opening, and locating convex block 1725 is positioned at the 3rd pair of detent 1734.As stopped dialysis treatment, retain perfusion treatment, make stop valve 421,451,481 be in opening, stop valve 431,471 is in closed condition, and locating convex block 1725 is positioned at second pair of detent 1734.
In the present embodiment, the thickness of dividing plate is between 3 millimeters to 10 millimeters, and near the first end caps, the thickness of dividing plate increases gradually, so that while installation to gauge tap, keep the smooth and continuous of perfusion chamber interior sidewall surface.The quantity of the first groove 114 and the second groove 116 is more than one, usually elects 2 to 4 as.In order to realize the quick position of pre-determined bit groove and pre-determined bit projection, mark in the position corresponding with cylindrical shell at end cap, or the pre-determined bit groove be positioned on same axial end has difformity or size.
Blood purification system second embodiment
As the explanation to blood purification system second embodiment of the present invention, only the difference with blood purification system first embodiment is described below.
See Figure 16, positioning convex 5714 end on the blind end of the inner cylinder 571 of gauge tap 57 expands and forms expanding end, the detent 5734 be located on the installation circular hole bottom surface of pedestal 573 is formed with the inflation lumen matched with expanding end, realizes being fixedly connected with inner cylinder 571 and pedestal 573 by coordinating of expanding end and inflation lumen.
Blood purification system the 3rd embodiment
As the explanation to blood purification system of the present invention 3rd embodiment, only the difference with above-mentioned blood purification system first embodiment is described below.
See Figure 17 and Figure 18, the knob 6721 in the outer cylinder 672 of gauge tap is fixedly connected with for dismountable with barrel 6720, and the installing hole 620 be formed on the first end cap 62 is the circular port matched with the outer peripheral face of outer cylinder 672.
By the compression of the first end cap 62 to the pedestal 673 be made up of elaxtic seal, realize being sealed and matched and fixing gauge tap between pedestal 673 and the first end cap 62.
Blood purification system the 4th embodiment
As the explanation to blood purification system of the present invention 4th embodiment, only the difference with blood purification system first embodiment is described below.
See Figure 19, outer cylinder 772 only has the first intercommunicating pore 7722 and the second intercommunicating pore 7723, as shown in the figure state, the first intercommunicating pore 7722 connects the first through hole 7712 and is communicated with the second through hole 7713 and fourth hole 7733 with third through-hole 7732, second intercommunicating pore 7723.
When outer cylinder 772 rotated counterclockwise by angle equals the center line angle of the first intercommunicating pore 7722 and the second intercommunicating pore 7723, the second intercommunicating pore 7723 is communicated with the first through hole 7712 and third through-hole 7732, and the second through hole 7713 and fourth hole 7733 are not communicated with.
When outer cylinder 772 again rotated counterclockwise by angle equal 360 degree deduct the twice of the center line angle of the first intercommunicating pore 7722 and the second intercommunicating pore 7723 time, first intercommunicating pore 7722 is communicated with the second through hole 7713 and fourth hole 7733, and the first through hole 7712 is not communicated with third through-hole 7732.
The axis of the first intercommunicating pore 7722 and the axis not conllinear of the second intercommunicating pore 7723, between the two axis, angle elects 90 degree to 150 degree usually as.
Blood purification system the 5th embodiment
As the explanation to blood purification system of the present invention 5th embodiment, only the difference with blood purification system first embodiment is described below.
Omit the first pre-determined bit projection and the draw-in groove on the buckle in the second pre-determined bit projection and the first pre-determined bit groove and the second pre-determined bit groove.
By use bonding agent or ultra-sonic welded by protruding for pre-determined bit with carry out bonding between pre-determined bit groove or weld and be fixedly connected with.
Blood purification system the 6th embodiment
As the explanation to blood purification system of the present invention 6th embodiment, only the difference of blood purification system first embodiment is described below.
Omit the first pre-determined bit groove, the first pre-determined bit projection, the second pre-determined bit groove, the second pre-determined bit projection and the buckle be located on them and draw-in groove.
See Figure 20 and Figure 21, the first axial end lateral wall of cylindrical shell 81 is provided with position corresponding with the first outer shaft shoulder 813 on the first outer shaft shoulder 813, first end cap 82 and has axially extended to form the first annular periphery 823 along cylindrical shell 81.
The lateral wall of the first axial end is formed with fin, the medial surface of the first annular periphery is formed with the groove matched with fin, fin realizes end cap and cylindrical shell location in the circumferential with coordinating of groove, and uses bonding agent or ultra-sonic welded to carry out bonding between annular periphery and the outer end wall of cylindrical shell or to weld and be fixedly connected with.
The mode that is fixedly connected with between second end cap with cylindrical shell 81 and the first end cap 82 with between cylindrical shell 81 to be fixedly connected with mode identical, do not repeat them here.
Central scope of the present invention is by arranging syndeton, gauge tap and outer even port between perfusion unit and unit with dialysis, while improving blood purification treatment safety, simplifying the operating process of medical personnel.According to this design, the structure of gauge tap also has multiple apparent change; The structure of shell also has multiple apparent change, and the cross section of such as cylindrical shell is the shape such as ellipse or rectangle; Syndeton between end cap and cylindrical shell also has multiple apparent change, is such as threaded.
Claims (10)
1. apparatus for purifying blood, comprises perfusion unit, unit with dialysis, linkage unit and control unit;
Described perfusion unit comprises perfusion chamber, and the import of described perfusion chamber is the tremulous pulse port of described apparatus for purifying blood;
Described unit with dialysis comprises dialysis chamber, and the outlet of described dialysis chamber is the vein port of described apparatus for purifying blood;
It is characterized in that:
Described linkage unit comprises shell and dividing plate, and the chamber that described shell surrounds is separated into the first separate chamber and the second chamber by described dividing plate, and described first chamber is described perfusion chamber, and described second chamber is described dialysis chamber;
Described shell is provided with dialysis solution import and dialysis solution outlet in the side-walls of described dialysis chamber;
Described control unit comprises gauge tap and outer even port, and described gauge tap is used for being communicated with the two in the outlet of described perfusion chamber, the import of described dialysis chamber and described outer connectivity port selectively.
2. apparatus for purifying blood according to claim 1, is characterized in that:
Described shell comprises cylindrical shell, is fastened on the first end cap on the port of described cylindrical shell first axial end, and be fastened on described cylindrical shell the second axial end port on the second end cap;
Described dividing plate is axial arranged along described cylindrical shell;
The described first end cap position corresponding with described dividing plate is provided with the installing hole for installing described gauge tap, position corresponding with described installing hole on described dividing plate is provided with the mount pad for installing described gauge tap, and the outlet of described perfusion chamber and the import of described dialysis chamber are positioned at by the side of described mount pad accordingly;
Described tremulous pulse port is located at position corresponding with described perfusion chamber on the end wall of described second end cap, and described vein port is located at position corresponding with described dialysis chamber on the end wall of described second end cap;
Described dialysis solution import and the outlet of described dialysis solution are located on the sidewall of described cylindrical shell.
3. apparatus for purifying blood according to claim 2, is characterized in that:
Described dividing plate comprises central dividing plate, the first dividing plate and second partition;
Described first end covers the first container cavity of the axial open at one end be provided with at described first end cap, and described second end cap is provided with at the second uncovered container cavity of the axial Single port of described second end cap;
Described central dividing plate and described cylindrical shell are made in integrated mode, and the chamber of described cylindrical shell is separated into left chamber and right chamber;
Described first dividing plate and described first end cap are made in integrated mode, and described first container cavity is separated into the first left container cavity and the first right container cavity;
Described second partition and described second end cap are made in integrated mode, and described second container cavity is separated into the second left container cavity and the second right container cavity;
Described left chamber, described first left container cavity and described second left container cavity docking form described perfusion chamber, and described right chamber, described first right container cavity and described second right container cavity docking form described dialysis chamber;
Described mount pad is located on described first dividing plate.
4. apparatus for purifying blood according to claim 3, is characterized in that:
The internal face of described left chamber near the end of described first end cap is provided with the shaft shoulder in first, and the internal face near the end of described second end cap is provided with the shaft shoulder in second;
Be pressed with the port of export filter screen of described perfusion unit in the end face of described first end cap and described first between the shaft shoulder, in the end face of described second end cap and described second, between the shaft shoulder, be pressed with the entrance point filter screen of described perfusion unit;
Also comprise the first sealing gasket and the second sealing gasket, described first sealing gasket comprises the first connected O-ring seal portion and the first strip diaphragm seal portion, and described second sealing gasket comprises the second connected O-ring seal portion and the second strip diaphragm seal portion;
Described first O-ring seal portion is pressed between the end face of described first end cap and the end face of described first axial end, between the end face that described first strip diaphragm seal portion is pressed on described first dividing plate and the end face of described central dividing plate;
Described second O-ring seal portion is pressed between the end face of described second end cap and the end face of described second axial end, and described second strip diaphragm seal portion is pressed between the end face of described second partition and the end face of described central dividing plate.
5. apparatus for purifying blood according to claim 3, is characterized in that:
The end face outer rim of described first end cap convexes to form the first bulge loop that plural first pre-determined bit is protruding and be positioned at inside described first pre-determined bit projection;
On the end face of described first axial end, indent is formed with the first pre-determined bit groove matched with described first pre-determined bit projection and the first groove matched with described first bulge loop;
The end face outer rim of described second end cap convexes to form the second bulge loop that plural second pre-determined bit is protruding and be positioned at inside described second pre-determined bit projection;
On the end face of described second axial end, indent is formed with the second pre-determined bit groove matched with described second pre-determined bit projection and the second groove matched with described second bulge loop;
It is described that first pre-determined bit projection is fixedly connected with for permanent type buckle draw-in groove with between described first pre-determined bit groove, being adhesively fixed is connected or is welded and fixed connection;
It is described that second pre-determined bit projection is fixedly connected with for permanent type buckle draw-in groove with between described second pre-determined bit groove, being adhesively fixed is connected or is welded and fixed connection.
6. apparatus for purifying blood according to any one of claim 1 to 5, is characterized in that:
The pedestal that described gauge tap comprises inner cylinder, outer cylinder and is arranged on mount pad, described mount pad is located on described dividing plate;
It is outer and be sealed and matched with described inner cylinder that described outer cylinder can be placed on described inner cylinder rotatably around own axes;
Described pedestal is provided with installation circular hole, the blind end of described inner cylinder is fixedly connected with the bottom surface of described installation circular hole, one end of described outer cylinder is placed in described installation circular hole and also can rotates around own axes relative to described pedestal, for being sealed and matched between the outside wall surface of described outer cylinder and the internal face of described installation circular hole;
Described pedestal is provided with the second through hole with the first through hole of the outlet of described perfusion chamber and the inlet communication with described dialysis chamber, and position corresponding with described first through hole on the barrel of described inner cylinder is provided with third through-hole and the position corresponding with described second through hole is provided with fourth hole;
The barrel of described outer cylinder is provided with plural intercommunicating pore;
Described outer cylinder rotates around own axes, described intercommunicating pore is only communicated with described first through hole and described third through-hole selectively, or be only communicated with described second through hole and described fourth hole, or be communicated with described first through hole and described third through-hole and described second through hole and described fourth hole simultaneously;
Described inner cylinder is described outer even port away from the port of described blind end.
7. apparatus for purifying blood according to claim 6, is characterized in that:
Described first through hole, described second through hole, described third through-hole and described fourth hole coaxial line and this axis is mutually orthogonal with the plate face of described dividing plate;
Described intercommunicating pore comprises the first intercommunicating pore, the second intercommunicating pore and third connecting hole;
Described first intercommunicating pore and described second intercommunicating pore coaxial line and the axis in this axis and described third connecting hole is mutually orthogonal.
8. apparatus for purifying blood according to claim 6, is characterized in that:
Described outer cylinder can move along self axial reciprocating relative to described inner cylinder;
The outer tube wall of described inner cylinder is provided with the spacing outer shaft shoulder, and the inner tube wall of described outer cylinder is provided with the spacing interior shaft shoulder, and the described spacing outer shaft shoulder and the described spacing interior shaft shoulder are mutually against forming spacing away from described pedestal of described outer cylinder;
Described outer cylinder forms locating piece away from the described outer head face hump connecting port, and the bottom surface of described installation circular hole is formed with the locating slot matched with described locating piece, described locating slot comprises the first locating slot, the second locating slot and the 3rd locating slot;
Described outer cylinder is greater than along self axially movable distance the greatest length that described locating piece inserts described locating slot;
When described locating piece is positioned at described first locating slot, described intercommunicating pore is communicated with described first through hole and described third through-hole and described second through hole and described fourth hole simultaneously;
When described locating piece is positioned at described second locating slot, described intercommunicating pore is only communicated with described first through hole and described third through-hole;
When described locating piece is positioned at described 3rd locating slot, described intercommunicating pore is only communicated with described second through hole and described fourth hole.
9. blood purification system, comprises extracorporeal circulation pipeline and is connected to the apparatus for purifying blood in described extracorporeal circulation pipeline;
It is characterized in that:
Described apparatus for purifying blood is apparatus for purifying blood described in described any one of claim 1 to 8.
10. blood purification system according to claim 9, is characterized in that:
Described extracorporeal circulation pipeline comprises blood circuit arterial line, blood circuit venous line, the first threeway, the first tremulous pulse arm, the second tremulous pulse arm, the second threeway, intervalve, the 3rd threeway, the first vein arm and the second vein arm;
The first interface of described first threeway is connected with the rear port of described blood circuit arterial line, and the second interface is connected with the Single port of described first tremulous pulse arm, and the 3rd interface is connected with the Single port of described second tremulous pulse arm;
The another port of described first tremulous pulse arm is connected with described tremulous pulse port;
The first interface of described second threeway is communicated with the another port of described second tremulous pulse arm, and the second interface is connected with the Single port of described intervalve, and the 3rd interface is connected with the Single port of described second vein arm;
The another port of described intervalve is connected with the described outer port that connects;
The first interface of described 3rd threeway is connected with the another port of described second vein arm; Second interface is connected with the Single port of described first vein arm, and the 3rd interface is connected with the front port of described blood circuit venous line;
The another port of described second vein arm is connected with described vein port;
Described first tremulous pulse arm, described second tremulous pulse arm, described intervalve, described first vein arm and described second vein arm are equipped with stop valve.
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Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
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| WO2018077051A1 (en) * | 2016-10-28 | 2018-05-03 | 珠海健帆生物科技股份有限公司 | Blood purifier |
| CN109044825A (en) * | 2018-08-02 | 2018-12-21 | 珠海健帆生物科技股份有限公司 | A kind of soft bag container of haemodialysis concentrate |
| CN109464717A (en) * | 2018-12-24 | 2019-03-15 | 贝恩医疗设备(广州)有限公司 | A kind of dripping chamber for haemodialysis extracorporeal circulation pipeline |
| CN112451772A (en) * | 2020-12-21 | 2021-03-09 | 南通大学附属医院 | But real-time supervision's blood purification device |
| CN115107285A (en) * | 2022-06-16 | 2022-09-27 | 乾德生物医疗技术(重庆)有限公司 | Method for manufacturing blood purification device |
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| WO2018077051A1 (en) * | 2016-10-28 | 2018-05-03 | 珠海健帆生物科技股份有限公司 | Blood purifier |
| CN109044825A (en) * | 2018-08-02 | 2018-12-21 | 珠海健帆生物科技股份有限公司 | A kind of soft bag container of haemodialysis concentrate |
| CN109464717A (en) * | 2018-12-24 | 2019-03-15 | 贝恩医疗设备(广州)有限公司 | A kind of dripping chamber for haemodialysis extracorporeal circulation pipeline |
| CN109464717B (en) * | 2018-12-24 | 2024-05-28 | 贝恩医疗设备(广州)有限公司 | A drip room for hemodialysis extracorporeal circulation pipeline |
| CN112451772A (en) * | 2020-12-21 | 2021-03-09 | 南通大学附属医院 | But real-time supervision's blood purification device |
| CN115107285A (en) * | 2022-06-16 | 2022-09-27 | 乾德生物医疗技术(重庆)有限公司 | Method for manufacturing blood purification device |
| CN115107285B (en) * | 2022-06-16 | 2024-04-02 | 乾德生物医疗技术(重庆)有限公司 | Method for manufacturing blood purification device |
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Address after: 519080 Zhuhai hi tech Zone No. six road, Guangdong Province, 98 Patentee after: Jianfan Biotechnology Group Co., Ltd. Address before: 519080 Zhuhai hi tech Zone No. six road, Guangdong Province, 98 Patentee before: Jafron Biomedical Co., Ltd. |