CN205108526U - Blood purifying device and system - Google Patents

Blood purifying device and system Download PDF

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Publication number
CN205108526U
CN205108526U CN201520872801.7U CN201520872801U CN205108526U CN 205108526 U CN205108526 U CN 205108526U CN 201520872801 U CN201520872801 U CN 201520872801U CN 205108526 U CN205108526 U CN 205108526U
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blood
port
adsorption column
connectivity port
purifying blood
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董凡
陈莲华
杜鸿雁
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Jafron Biomedical Co Ltd
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Jafron Biomedical Co Ltd
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Abstract

The utility model provides a blood purifying device and the blood clean system who founds with this purifier belong to blood purification therapy apparatus field. Wherein, blood purifying device includes perfusion unit, dialysis unit and linkage unit. The perfusion unit includes the adsorption column, and along the axial of adsorption column, the filter chamber of adsorption column is separated into two -layer above filter layer by the baffle, is equipped with a plurality of on the baffle and is used for the intercommunication to be located the intercommunicating pore of this baffle both sides filter layer. The dialysis unit is including the dialysis post. The linkage unit includes a connection port, the 2nd connection port and is used for controlling the switch of opening and close of intercommunication between a connection port and the 2nd connection port, and a connection port is used for being connected with a port fixed seal of adsorption column, and the 2nd connection port is used for being connected with a port fixed seal of dialysis post. This blood purifying device has improved blood purification therapy's speed under the basic prerequisite that improves the blood purification therapy security.

Description

Apparatus for purifying blood and system
Technical field
This utility model relates to medical instruments field, specifically, and the blood purification system relating to a kind of apparatus for purifying blood and build with this apparatus for purifying blood.
Background technology
Combined artificial kidney is the apparatus for purifying blood that hemoperfusion (HP) is combined in a kind of hemodialysis (HD), it utilizes the advantage of hemoperfusion and hemodialysis fully, there is the advantages such as good biocompatibility, untoward reaction is few, the blood purification time is short, and the various toxin in the patient such as uremia can be removed comprehensively.
The blood purification system of existing combined artificial kidney composition is made up of blood circuit venous line four part flowing out the blood circuit arterial line of human body, perfusion device, dialyser and flow into human body.As shown in Figure 1, blood circuit arterial line is provided with the arterial end 01, blood pump 02, tremulous pulse kettle 03 and the tremulous pulse kettle side pipe 04 be located on tremulous pulse kettle 03 that are connected by pipeline successively in direction of flow of blood; Blood circuit venous line is provided with the venous chambers 012 and vein end 014 that are connected by pipeline successively in direction of flow of blood, and is located at the venous chambers side pipe 013 on venous chambers 012; The blood mouth of perfusion device 07 front end is connected with the rear port of blood circuit arterial line by connectivity port 06, and is provided with a safety clamp 05 between the rear port of connectivity port 06 and blood circuit arterial line; The blood mouth of dialyser 011 front end is connected with the blood mouth of perfusion device 07 rear end by connectivity port 08 and connectivity port 010, is provided with a safety clamp 09 between connectivity port 08 and connectivity port 010; The blood mouth of dialyser 011 rear end is connected with the front port of blood circuit venous line.The clinical treatment mode of this blood purification system is that first hemodialysis (HD) is combined hemoperfusion (HP) and treated 2 hours, carry out separately hemodialysis 2 hours again, by the work of blood pump 02, arterial blood is extracted out through perfusion device 07 and dialyser 011 or the purification only through dialyser 011 after being removed by perfusion device 07, again through blood circuit venous line, by through detoxification, anhydrate, electrolyte exchange after in the defeated the Huis' body of blood that purified, temporarily play the effect of alternative human kidney function.
Perfusion device carries out absorption by the adsorbent be filled in its adsorption column filter chamber to blood and reaches purification object, blood perfusion device is quickly move through to shorten the blood purification treatment time in order to enable blood, along with the increase of blood flow in perfusion device, perfusion device internal blood applied pressure is also increased thereupon, be limited to the maximum pressure that perfusion device inside can bear, the maximum blood flow causing existing conventional blood perfusion device to allow is generally 200 ml/min.But, with blood perfusion device with the use of the hemodialyzer maximum blood flow that can allow can reach 300 ml/min to 400 ml/min, in therapeutic alliance process, the blood flow of whole combined artificial kidney is restricted to below 200 ml/min, the time of blood purification treatment is caused to lengthen, be unfavorable for the carrying out of blood purification treatment, and increase blood purification treatment cost.
In addition, owing to needing the water taking off certain volume in dialysis procedure, and be limited to the maximum blood flow that perfusion device allows, after carrying out therapeutic alliance, have to first to pull down the pipeline be connected on perfusion device and be connected to dialyser again, carry out independent dialysis treatment.In this process, operator need to shut down, and pull down perfusion device and associated pipe, carry out blood back operation, in the process of dismounting perfusion device, need to disconnect blood circuit, carry out dismantling, the sequence of operations such as short circuit, and this adds the workload of operator clinically; And if nurse occurs misoperation in clinical manipulation process, blood samples of patients may be caused to lose, increase pathogenic bacteria invades the probability in blood samples of patients, increases patient painful, even can threaten to the life of patient.
Summary of the invention
Main purpose of the present utility model is to provide a kind of apparatus for purifying blood simultaneously possessing hemoperfusion and hemodialysis function, with under the basic prerequisite improving blood purification treatment safety, improves the speed of blood purification treatment;
Another object of the present utility model is to provide the blood purification system that more than one state apparatus for purifying blood structure.
In order to realize above-mentioned main purpose, the apparatus for purifying blood that this utility model provides comprises perfusion unit, unit with dialysis and linkage unit.Perfusion unit comprises adsorption column, and along the axis of adsorption column, the filter chamber of adsorption column is become two-layer above filter course by baffle for separating, and dividing plate is provided with several for being communicated with the intercommunicating pore being positioned at this dividing plate double-side filtering layer.Unit with dialysis comprises dialysis cartridge.Linkage unit comprises the first connectivity port, the second connectivity port and for controlling the open-close on-off be communicated with between the first connectivity port with the second connectivity port, first connectivity port is used for a port fixed seal connection with adsorption column, and the second connectivity port is used for a port fixed seal connection with dialysis cartridge.
From above scheme, integrally, tool possesses hemoperfusion and hemodialysis function to whole apparatus for purifying blood simultaneously, can provide better blood purification treatment for patient.In blood purification process, simple with the connection of transducer potector, while simplifying the operation, improve safety in utilization.By closed open-close on-off, the inner chamber environment of adsorption column and the inner chamber environment of dialysis cartridge are isolated, the adsorbent fragment that may exist in adsorption column is avoided to enter in dialysis cartridge, the dialysis function of dialyzer is impacted, by dialyzer and the different requirements of adsorbent to storage environment humidity, dry wet preservation can be realized accordingly simultaneously.By arranging the dividing plate with intercommunicating pore in adsorption column filter chamber, reduce adsorbent and occur that gathering is united phenomenon, thus the maximum permissible value of blood flow in lifting adsorption column, and then improve the speed of therapeutic alliance, reduce the blood purification treatment time, the pipeline occurred in dialysing separately again without the need to first therapeutic alliance in haemodialysis process is dismantled and is connected, improves the safety of blood purification treatment.
Concrete scheme is every layer of filter course, and to hold the capacity of adsorbent all equal, or every layer of filter course to hold the thickness of adsorbent all equal, or every layer of filter course hold adsorbent capacity be all less than or equal to 20 milliliters.In further raising adsorption column, blood flow
Another concrete scheme is the total capacity of adsorbent in adsorption column is 20 milliliters to 600 milliliters, and in dialysis cartridge, the gross area of dialyzer is 1.2 square metres to 2.0 square metres.
A preferred scheme is that linkage unit comprises sleeve and the interlayer board for this barrel bore being separated into above-mentioned first connectivity port and the second connectivity port, the centre in interlayer board plate face is provided with more than one via for conducting first connectivity port and the second connectivity port, by coordinating, to control being communicated with between the first connectivity port with the second connectivity port of open-close on-off and this via.The structure of linkage unit is simple, reliability is high and be convenient to manufacture assembling.
Preferred scheme is that the hole area summation of via is more than or equal to 10 square millimeters.The impact that effective reduction via produces blood pressure.
Another preferred scheme is the via that the centre of interlayer board is provided with that a diameter is 4 millimeters to 10 millimeters.The impact that effective reduction via produces blood pressure.
Another preferred scheme is that the Single port of adsorption column is closed by closing component, and another port is fixedly connected with sleeve with the threaded engagement of the female thread be located on the first connectivity port medial surface by the external screw thread be located on its lateral surface.The Single port of dialysis cartridge is closed by end cap, and another port is fixedly connected with sleeve with the threaded engagement of the female thread be located on the second connectivity port medial surface by the external screw thread be located on its lateral surface.Structure is simple, spare and accessory parts are few, easy to assembly, effectively lowers product cost.
Further scheme is the filter screen in closing component is columnar filter screen, this columnar filter screen comprises ring-type rack, spherical crown housing, mesh sheet and for spherical crown housing being fixed on the pole on the entrance point of ring-type rack, have gap between the medial surface of spherical crown housing and ring-type rack, mesh sheet periphery is fixedly connected with the medial surface of ring-type rack; The central axis upright of ring-type rack is in the end face of spherical crown shell nozzle end, and the radial center of this end face is positioned on the central axis of ring-type rack; Opening is arranged towards the direction being pointed to its entrance point by the port of export of ring-type rack; Along the axis of ring-type rack, mesh sheet is between spherical crown housing and the port of export.Can effectively reduce axial flow phenomenon, improve the effect of Blood index.
Another preferred scheme is that linkage unit also comprises for entering line-locked locking mechanism to the open/close states of open-close on-off, and the indicating mechanism for indicating the open/close states of open-close on-off.The operation of convenient operation personnel and prevent maloperation, improves the safety of blood purification treatment.
Further scheme is open-close on-off is valve, and this valve comprises flap and valve rod, valve rod for drive flap along valve rod move axially or around the center axis thereof of valve rod; Locking mechanism comprises shadoof, latch, elastic component and locking wheel, and the circumference of locking wheel is provided with the first lock slots and the second lock slots; Lock gear is with valve rod coaxial arrangement and be fixedly connected with, and one end of shadoof is fixedly connected with latch, and latch inserts in the first lock slots or described second lock slots selectively; The elastic restoring force of elastic component stops latch to exit from insert state.The structure of locking mechanism is simple and effective.
The adsorbent that another preferred scheme is held for every layer of filter course in adsorption column filter chamber is same adsorbent.
Another preferred scheme is adsorption column is a circular platform type shell structure, and the smaller diameter end port of this circular platform type shell structure docks with linkage unit first connectivity port.Be convenient to and the docking of unit with dialysis, and be convenient in filter chamber, dividing plate is installed in an assembling process.
In order to realize another object above-mentioned, the blood purification system that this utility model provides comprises blood transducer potector and is connected to the liquid purifier in this transducer potector.Wherein, the apparatus for purifying blood that provides for above-mentioned arbitrary technical scheme of apparatus for purifying blood.
Accompanying drawing explanation
Fig. 1 is the transducer potector connection diagram of existing blood purification system;
Fig. 2 is the transducer potector connection diagram of this utility model blood purification system first embodiment;
Fig. 3 is the structural representation of apparatus for purifying blood in this utility model blood purification system first embodiment;
Fig. 4 is the STRUCTURE DECOMPOSITION schematic diagram of apparatus for purifying blood in this utility model blood purification system first embodiment;
Fig. 5 is the schematic diagram that the stop valve of linkage unit in this utility model blood purification system first embodiment is in closure state;
Fig. 6 is the schematic diagram that the stop valve of linkage unit in this utility model blood purification system first embodiment is in opening;
Fig. 7 is the first viewing angle constructions figure of the filter of perfusion unit in this utility model blood purification system first embodiment;
Fig. 8 is the second viewing angle constructions figure of the filter of perfusion unit in this utility model blood purification system first embodiment;
Fig. 9 is the axial cross-sectional schematic of the columnar filter screen of perfusion unit closing component in this utility model blood purification system first embodiment;
Figure 10 is the columnar filter screen schematic top plan view of perfusion unit closing component in this utility model blood purification system first embodiment;
Figure 11 is the structural representation of locking mechanism in open-close on-off in this utility model blood purification system second embodiment.
Below in conjunction with embodiment and accompanying drawing thereof, the utility model is described in further detail.
Detailed description of the invention
This utility model mainly improves the structure of apparatus for purifying blood in blood purification system, relate generally to the internal structure of adsorption column filter chamber and the syndeton between adsorption column and dialysis cartridge, with under the prerequisite improving blood purification treatment safety, improve the speed of blood purification treatment, other part-structures of blood purification system design according to existing product.
Following embodiment is mainly for blood purification system of the present utility model, because this utility model blood purification system have employed apparatus for purifying blood of the present utility model, to the explanation of apparatus for purifying blood embodiment in the explanation of blood purification system embodiment.
Blood purification system first embodiment
Blood purification system is made up of blood circuit venous line three part flowing out the blood circuit arterial line of human body, apparatus for purifying blood and flow into human body.
See Fig. 2, along on the direct of travel of blood in pipeline, blood circuit arterial line is provided with the arterial end 11, blood pump 12 and the tremulous pulse kettle 13 that are connected by transducer potector successively, and on tremulous pulse kettle 13, be provided with tremulous pulse kettle side pipe 14; Blood circuit venous line is provided with the venous chambers 16 and vein end 18 that are connected by transducer potector successively, and is provided with venous chambers side pipe 17 on venous chambers 16.
Apparatus for purifying blood 2 is made up of with unit with dialysis 23 perfusion unit 21, linkage unit 22.Apparatus for purifying blood 2 front end is connected with the rear port of blood circuit arterial line by the blood mouth on perfusion unit, and is provided with safety clamp 15 on blood circuit arterial line rear end; Apparatus for purifying blood 2 rear end is connected with the front port of blood circuit venous line by the blood mouth on unit with dialysis 23.
See 3 and Fig. 4, perfusion unit 21 is by closing component 211, and adsorption column 212, is located at the filter screen 213 at adsorption column 212 port of export 2123 place, and the adsorbent be placed in adsorption column 212 filter chamber 2120 is formed.Adsorbent can be the combination of one or more in the blood-purifying adsorbing agents such as resin sorbent, acticarbon, natural macromolecule adsorbent.
Because perfusion unit 21 is for realizing the function of blood perfusion device in existing blood purification system, in the present embodiment, closing component 211 adopts the entrance point of the closing component of existing blood perfusion device to adsorption column 212 to close, such as notification number is adopted to be the closing device in the combination type blood perfusion device for artificial kidney disclosed in the patent documentation of CN201211355Y, this closing device is by filter screen, sealing plain cushion, end cap, locking nut and block are formed, the radial centre of end cap lid is provided with blood mouth 2110, blood mouth 2110 is for being connected with the rear port of blood circuit arterial line.
Adsorption column 212 is a circular platform type shell structure, and closing component 211 is for the larger diameter end port of closed circular bench-type shell structure.The filter chamber internal fixtion of adsorption column 212 has a dividing plate, and dividing plate is filter 2121, for the filter chamber 2120 of adsorption column 212 is separated into the roughly equal filter course of upper and lower two volumes, is respectively the first filter course 21201 and the second filter course 21202.The small diameter ports of circular platform type shell structure is the port of export 2123 with the fixed seal connection of linkage unit 22 entrance point.The lateral surface of the port of export 2123 is formed with the external screw thread for being fixedly connected with the entrance point of linkage unit 22.
The axial cross section of linkage unit 22 is an I-shaped structure, it has sleeve 220 and is located at the circular interlayer board 221 in the middle part of sleeve 220 inner chamber, sleeve 220 is separated into upper and lower two ports by circular interlayer board 221, be respectively entrance point 222 and the port of export 223, circular interlayer board 221 is provided with for being communicated with entrance point 222 and the via 224 of the port of export 223, is provided with and opens closed open-close on-off 225 for controlling via 224 in via 224.Entrance point 222 medial surface is formed with the female thread for being fixedly connected with the port of export 2123.The medial surface of the port of export 223 is formed with the external screw thread for being fixedly connected with the entrance point of unit with dialysis 23.
Unit with dialysis 23, for realizing the function of dialyser in existing blood purification system, is made up of dialysis cartridge 231, end cap 232 and block.Entrance point 2310 lateral surface of dialysis cartridge 231 is formed with the external screw thread for being fixedly connected with the port of export 223.Accommodate dialyzer in the container cavity of dialysis cartridge 231, dialyzer can be the hemodialysis membrane of the materials such as polyether sulfone, polysulfones, polypropylene.Be provided with bonding glue-line 2311 at the both ends of dialysis cartridge 231 container cavity, between two bonding glue-lines 2311 and both being positioned at, side place is provided with dialysis solution outlet 2313 and dialysis solution import 2312.The radial centre of the discoideus lid of end cap 232 is provided with blood mouth 2320, and blood mouth 2320 is for being connected with the front port of blood circuit venous line.
Open-close on-off 225 is plug valve or is stop valve as illustrated in figures 5 and 6, stop valve is made up of flap 2251, nut casing 2252, valve rod 2253 and handle 2254, handle 2254 is fixedly connected with one end of valve rod 2253, valve rod 2253 other end end lateral surface is formed with the external screw thread matched with nut casing 2252 female thread, and flap 2251 is fixedly connected with nut casing 2252 one end away from valve rod 2253.
Filter screen 213 and filter 2121 adopt integrated injection molding formula filter screen 3 as shown in Figures 7 and 8, and it is made up of circular rack 31 and the wet end 32 that is positioned at rack 31, rack 31 and wet end 32 integrated injection molding.Integrated injection molding formula filter screen 3 is by polypropylene or Merlon or SBS(styrene butadiene styrene block copolymer (SBS)) material injection forms.Due to rack 31 and wet end 32 integrated injection molding, the problem that the wet end 32 after injection moulding easily comes off from rack 31 can be avoided, simplified processing process and enhancing productivity.Wet end 32 has circular ring frame 321 and the many reinforcements 322 extended along wet end 32 radial direction.Because integrated injection molding formula filter screen 3 has good air permeable effect, apparatus for purifying blood is made to avoid occurring the problem of aerofluxus difficulty when rushing in advance.
Filter screen in the present embodiment in closing component 21 can adopt integrated injection molding formula filter screen 3 as shown in Figures 7 and 8, also the columnar filter screen 4 shown in Fig. 9 and 10 can be adopted, columnar filter screen 4, by ring-type rack 41 and the spherical crown housing 43 that is fixed on by four poles 42 in the first half of annular rack 41 inner chamber, has mesh sheet 44 at the Lower Half internal fixtion of annular rack 41 inner chamber.Blood in adsorption column 212 is entered by intracavity in injection spherical crown housing 43 from blood mouth 2210, surrounding from spherical crown housing 43 is overflowed and is dispersed in mesh sheet 44 by the blood after filling, thus effectively avoid velocity of blood flow too fast and occur axial flow phenomenon, maximally play the adsorption of filter chamber internal adsorption agent.The injection moulding filter screen of the preferred structure as shown in FIG. 9 and 10 of the filter screen in the present embodiment closing component 21.
The assembling process of apparatus for purifying blood 2 is as follows:
(1) close the open-close on-off 225 on linkage unit 22, be positioned on the first side, side, connectivity port 222 at circular bulkheads 221 and place sealing plain cushion.
(2) filter screen 213 to be loaded on perfusion unit 21 adsorption column 212 away from closing component one end, and be fixed, then coordinate with to be located on the port of export 2123 externally threaded by being located at female thread on entrance point 222, be socketed on by entrance point 222 outside the port of export 2123 and be also sealedly and fixedly connected with it, the secure fit of sealing plain cushion to the two being positioned over the first side, connectivity port 222 plays sealing function.
Ground floor adsorbent is filled in (3) second filter courses 21202; Then, be connected with the buckle of the buckle 2122 be located on inside adsorption column 212 by the screens be located on filter 2121, or adopt the mode of welding to be fixed on by filter 2121 on the medial wall of adsorption column 212; Then in the second filter course 21201, second layer adsorbent is filled, the capacity of ground floor adsorbent is slightly smaller than the capacity of second layer adsorbent, make the first adsorption layer and the adsorbent that the second adsorption layer holds substantially equal along adsorption column 212 thickness axially, then closing component 211 is fixedly connected on the entrance point of adsorption column 212.Filter screen in closing component 211 and filter screen 213 are positioned at the two-port place of adsorption column 212, go out to flow out from its two-port for preventing adsorbent.
(4) side, side being positioned at the second connectivity port 223 at circular bulkheads 221 is placed sealing plain cushion, inside is accommodated dialyzer, and dialysis cartridge 231 lower end that is fixed dialyzer by adhesive linkage, two ends and end cap 232 are sealedly and fixedly connected, blood mouth 2320 is connected with block, and dialysis solution outlet 2313 and dialysis solution import 2312 are fixedly connected with cap sealed respectively.By the threaded engagement of the female thread on the external screw thread on entrance point 2310 and the port of export 223, be sealedly and fixedly connected with linkage unit 22 by the adsorption column 231 be pre-installed, the secure fit of sealing plain cushion to the two being positioned over the second side, connectivity port 223 seals.
(5) after the assembling completing apparatus for purifying blood 2, the direction along unit with dialysis 23 to perfusion unit 21 purifies apparatus for purifying blood 2, finally carries out sterilizing and packaging to whole apparatus for purifying blood again.
In storage after completing production and transportation, open-close on-off 225 is in closure state all the time, be on the one hand in case the fragment that may exist due to adsorbent in adsorption column 212 is entered on the dialyzer in dialysis cartridge 231 by filter screen 213, affect the safety and effectiveness of dialyzer.On the other hand, adsorption column 212 may be different from the storage mode of dialysis cartridge 231, and such as dialysis cartridge 231 is inner is dry state preservation, and the inside of adsorption column 212 is hygrometric state preservation, or the two is contrary, thus isolates the two inside, effectively guarantee the effectiveness used.
In use, first apparatus for purifying blood is rushed heparinization in advance, and then carry out blood purification treatment.Wherein, pre-punching can select the one in following two kinds of pre-punching methods to rush in advance:
The first pre-punching method is, along gravity direction, unit with dialysis 23 is positioned at the top of perfusion unit 21, after connecting pipeline, rush liquid in advance and enter dialysis cartridge 231 from blood mouth 2320, open open-close on-off 225, make to rush in advance liquid first to rush dialysis cartridge 231 in advance and then rush in advance through adsorption column 212 pairs of adsorption columns 212, to make in adsorption column the adsorbent fragment in 212 be rushed liquid in advance to go out from blood mouth 2110, until pre-punching to meet treatment require time, apparatus for purifying blood 2 is turned, make the blood mouth 2110 of perfusion unit 21 upward, and then rush in advance, thus contribute to the thorough emptying of bubble of perfusion unit 21 inside, effectively avoid adsorbent fragment to enter in dialysis cartridge 231 simultaneously, affect the dialysis function of dialysis cartridge 231, improve the safety in utilization of apparatus for purifying blood.
The pre-punching method of the second is, along gravity direction, unit with dialysis 23 is positioned at the below of perfusion unit 21, treat to fill in dialysis cartridge 231 rush liquid in advance after open open-close on-off 225, rushing liquid in advance enters dialysis cartridge 231 from blood mouth 2320, then by adsorption column 212, the two is rushed in advance, the liquid that rushes in advance in adsorption column 212 is effectively avoided to reflux in dialysis cartridge 231 under gravity, adsorbent fragment is also brought into the dialysis function affecting dialyzer in dialysis cartridge 231, and this pre-punching method can make the quick emptying of bubble of perfusion unit 21 inside.
In the present embodiment, adsorption column 212, sleeve 220, through hole 224 and dialysis cartridge 231 coaxial arrangement.In order to make the pressure in perfusion unit 21 inside and unit with dialysis 23 inside maintenance safety range, and blood flows through through hole 224 with increasing without pressure, the diameter of through hole is more than 4 millimeters, is preferably 4 millimeters to 10 millimeters, reduces blood in apparatus for purifying blood 2, occurs blood coagulation, haemolysis equivalent risk.
Because blood is to the effect of adsorbent generation viscosity, adsorbent extrudes towards a direction along with blood flow, and under blood viscous effect, occur that gathering is united phenomenon, thus the damping force improved blood flow, the increase of blood flow promotes gathering to unite phenomenon further, the blood flow in adsorption column 212 is caused to be difficult to further raising, and the present embodiment uses filter the filter chamber 2120 of adsorption column 212 to be separated into two along Blood index post 212 filter course that axially adsorbent thickness is substantially equal, occur that gathering is united effect to reduce over the agent of filter chamber internal adsorption, under the basic prerequisite improving safety, improve the maximum permissible value of blood flow in adsorption column 212.The diameter of the mesh of filter 2122 is 200 microns to 600 microns, is preferably 300 microns to 500 microns.Adsorbent can be of the same race or multiple adsorbent composition.
Adsorbent capacity in adsorption column 212 is 20 milliliters to 600 milliliters, and be preferably 20 milliliters to 130 milliliters, in dialysis cartridge 231, the area of dialyzer is 1.2 square metres to 2.0 square metres.
When the capacity of every layer of filter course is less than 20 milliliters, can further improve the blood flow in the unit interval in adsorption column 212.
Blood purification system second embodiment
As the explanation to this utility model blood purification system second embodiment, only the difference with blood purification system first embodiment is described below.
Open-close on-off on linkage unit is made up of stop valve, locking mechanism and indicating mechanism.Stop valve as shown in Figures 5 and 6, is made up of flap 2251, nut casing 2252, valve rod 2253 and handle 2254.
See Figure 11, locking mechanism is by elastic component, latch 53, shadoof 54 and and the locking wheel 51 that be fixedly connected with coaxial with valve rod 2253 are formed, and elastic component is spring 52, the circumference of locking wheel 51 is formed with the first lock slots 511 and the second lock slots 512 radially arranged.Spring 52 one end is connected on latch 53, and the other end is fixedly connected on linkage unit; Shadoof 54 is fixedly connected on latch 53 one end near spring 52.When switching open-close on-off, need first pull shadoof 54, make the first lock slots 511(in locking wheel 51 as closed condition) be separated with latch 53, then rotary handle 2254, after decontroling shadoof 54, under the effect of spring 52 restoring force, latch 53 inserts in the second lock slots 512 of lock gear 51 (as open mode), thus make open-close on-off 225 from the first state as open mode switches to the second state as closed condition, and complete the locking to valve rod 2253 by locking mechanism.When needs switch to the first state from the second state, same first pulls shadoof 54, and then opposite direction rotary handle 2254, then the open/close states realizing open-close on-off switches.Locking mechanism is avoided effectively in transport and storing process under unartificial External Force Acting, and stop valve is opened, or is closed in blood purification process, thus produces unnecessary impact.
Indicating mechanism is by the keying indicating graduation portrayed on sleeve lateral surface and form with the instruction of portraying on handle.
Annular interlayer board is provided with multiple via for conducting first connectivity port and the second port, and via is uniformly distributed around the circumference of sleeve, and the hole area sum of via is greater than 10 square millimeters.The quantity of stop valve and the profile of flap 2251 all match with corresponding via.
Blood purification system the 3rd embodiment
As the explanation to this utility model blood purification system the 3rd embodiment, only the difference with blood purification system first embodiment is described below.
Adsorbent capacity in adsorption column 212 is 20 to 130 milliliters, and filter chamber is divided into four filter courses by three pieces of dividing plates, and the capacity of each filter course is all less than or equal to 20 milliliters, and dividing plate is sieve-plate structure, and sieve aperture forms the intercommunicating pore of connecting partition double-side filtering layer.
Blood purification system the 4th embodiment
As the explanation to this utility model blood purification system the 4th embodiment, only the difference with blood purification system the 3rd embodiment is described below.
The adsorbent filled in each filter course is all identical and capacity is identical.
Blood purification system the 5th embodiment
As the explanation to this utility model blood purification system the 5th embodiment, only the difference with blood purification system first embodiment is described below.
The quantity of adsorption column internal partition is 2 pieces, filter chamber is separated into the filter course that three layers of capacity is equal, the adsorption column two ends of perfusion unit seal by closing component, just be installed on closing component on the port of export and omit block, being installed on the blood mouth that closing component middle-end on the port of export covers is Rule female joint, the entrance point of linkage unit is provided with in Rule male joint and lateral surface that match with blood mouth and is formed with the external screw thread matched with the female thread of locating dowel on end cap, on end cap, fixed leg is notification number is locating dowel 404 disclosed in CN201211355Y, this Rule male joint is communicated with the via be located on circular interlayer board.
In an assembling process, first perfusion unit and unit with dialysis are pre-installed, more respectively by the two and linkage unit fixed seal connection.
Blood purification system the 6th embodiment
As the explanation to this utility model blood purification system the 6th embodiment, only the difference with blood purification system the 5th embodiment is described below.
Adsorption column is cylinder type.
The entrance point of dialysis cartridge is also closed by end cap, blood mouth on end cap is Rule female joint structure, the periphery of blood mouth is provided with locating dowel, and the port of export of linkage unit is provided with Rule male joint matched with this blood mouth and the external screw thread matched with the female thread of locating dowel.
Blood purification system the 7th embodiment
As the explanation to this utility model blood purification system the 7th embodiment, only the difference with blood purification system the 5th embodiment is described below.
The port of export of adsorption column is a unitary body, and the main body by the end cap in closing component and adsorption column is made in integrated mode, and omits the locking nut in closing component.
Blood purification system the 8th embodiment
As the explanation to this utility model blood purification system the 8th embodiment, only the difference with blood purification system first embodiment is described below.
Butterfly valve is adopted to substitute stop valve, butterfly valve has flap and valve rod to form, the profile of flap and the medial surface of via match, and drive flap to rotate around the central axis of valve rod and close or open via being communicated with the first connectivity port and the second connectivity port by valve rod.
In each embodiment above-mentioned, owing to improve the blood flow maximum permissible value of perfusion unit, making to use adsorption column and dialysis cartridge therapeutic alliance in whole blood purification treatment process always, reducing the time consumption because of bringing in detaching pipelines and assembling pipeline process and security risk.
Central scope of the present utility model is by the internal structure to adsorption column filter chamber and the improvement of syndeton between adsorption column and dialysis cartridge, to provide the compound apparatus for purifying blood of a high blood flux, under the basic prerequisite improving blood purification treatment safety, improve the speed of blood purification treatment.According to this design, the structure of dividing plate and quantity, the structure of linkage unit, the shape of closing component and adsorption column in perfusion unit, the structure of perfusion unit also has multiple apparent change.

Claims (13)

1. apparatus for purifying blood, comprises perfusion unit, unit with dialysis and linkage unit;
Described perfusion unit comprises adsorption column;
Described unit with dialysis comprises dialysis cartridge;
It is characterized in that:
Along the axis of described adsorption column, the filter chamber of described adsorption column is become two-layer above filter course by baffle for separating, and described dividing plate is provided with several for being communicated with the intercommunicating pore of the described filter course being positioned at these dividing plate both sides;
Linkage unit, described linkage unit comprises the first connectivity port, the second connectivity port and for controlling the open-close on-off be communicated with between described first connectivity port with described second connectivity port, described first connectivity port is used for a port fixed seal connection with described perfusion unit, and described second connectivity port is used for a port fixed seal connection with described unit with dialysis.
2. apparatus for purifying blood according to claim 1, is characterized in that:
The thickness of the adsorbent that every layer of described filter course holds is all equal or capacity is all equal or capacity is all less than or equal to 20 milliliters.
3. apparatus for purifying blood according to claim 1, is characterized in that:
In described adsorption column, the total capacity of adsorbent is 20 milliliters to 600 milliliters, and in described dialysis cartridge, the gross area of dialyzer is 1.2 square metres to 2.0 square metres.
4. apparatus for purifying blood according to any one of claims 1 to 3, is characterized in that:
Described linkage unit comprises sleeve and the interlayer board for the inner chamber of described sleeve being separated into described first connectivity port and described second connectivity port, and described interlayer board is provided with more than one via for the first connectivity port described in conducting and described second connectivity port;
By coordinating of described open-close on-off and described via, control being communicated with between described first connectivity port with described second connectivity port.
5. apparatus for purifying blood according to claim 4, is characterized in that:
The summation of the hole area of described via is more than or equal to 10 square millimeters.
6. apparatus for purifying blood according to claim 4, is characterized in that:
The centre of described interlayer board is provided with the described via that a diameter is 4 millimeters to 10 millimeters.
7. apparatus for purifying blood according to claim 4, is characterized in that:
The Single port of described adsorption column is closed by closing component, and another port is fixedly connected with described sleeve with the threaded engagement of the female thread on the medial surface being located at described first connectivity port by the external screw thread be located on its lateral surface;
The Single port of described dialysis cartridge is closed by end cap, and another port is fixedly connected with described sleeve with the threaded engagement of the female thread on the medial surface being located at described second connectivity port by the external screw thread be located on its lateral surface.
8. apparatus for purifying blood according to claim 7, is characterized in that:
Filter screen in described closing component is columnar filter screen, described columnar filter screen comprises ring-type rack, spherical crown housing, mesh sheet and for described spherical crown housing being fixed on the pole on the entrance point of described ring-type rack, have gap between the medial surface of described spherical crown housing and described ring-type rack, the periphery of described mesh sheet is fixedly connected with the medial surface of described ring-type rack;
The central axis upright of described ring-type rack is in the end face of the opening of described spherical crown housing, and the radial center of described end face is positioned on described central axis;
Described opening is arranged towards the direction being pointed to described entrance point by the port of export of described ring-type rack;
Along the axis of described ring-type rack, described mesh sheet is between described spherical crown housing and the described port of export.
9. apparatus for purifying blood according to any one of claims 1 to 3, is characterized in that:
Described linkage unit also comprises for entering line-locked locking mechanism to the open/close states of described open-close on-off, and the indicating mechanism for indicating the open/close states of described open-close on-off.
10. apparatus for purifying blood according to claim 9, is characterized in that:
Described open-close on-off is valve, and described valve comprises flap and valve rod, described valve rod for drive described flap along described valve rod move axially or around the center axis thereof of described valve rod;
Described locking mechanism comprises shadoof, latch, elastic component and locking wheel, and the circumference of described locking wheel is provided with the first lock slots and the second lock slots;
Described lock gear is with described valve rod coaxial arrangement and be fixedly connected with, and one end of described shadoof is fixedly connected with described latch, and described latch inserts described first lock slots or the second lock slots selectively;
The elastic restoring force of described elastic component stops described latch to exit from insert state.
11. according to any one of claims 1 to 3 apparatus for purifying blood, it is characterized in that:
Described adsorption column is a circular platform type shell structure, and the port of the smaller diameter end of described circular platform type shell structure docks with described first connectivity port.
12. according to any one of claims 1 to 3 apparatus for purifying blood, it is characterized in that:
Adsorbent in described adsorption column is adsorbent of the same race.
13. blood purification systems, comprise transducer potector and are connected to the apparatus for purifying blood in described transducer potector;
It is characterized in that:
Described apparatus for purifying blood is apparatus for purifying blood described in any one of claim 1 to 12.
CN201520872801.7U 2015-11-02 2015-11-02 Blood purifying device and system Active CN205108526U (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105214156A (en) * 2015-11-02 2016-01-06 珠海健帆生物科技股份有限公司 Apparatus for purifying blood and system
CN109157687A (en) * 2018-10-23 2019-01-08 贝恩医疗设备(广州)有限公司 A kind of dialyzer closing device
CN109758631A (en) * 2019-01-28 2019-05-17 江苏关怀医疗科技有限公司 A kind of absorption type haemodialyser

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105214156A (en) * 2015-11-02 2016-01-06 珠海健帆生物科技股份有限公司 Apparatus for purifying blood and system
CN109157687A (en) * 2018-10-23 2019-01-08 贝恩医疗设备(广州)有限公司 A kind of dialyzer closing device
CN109758631A (en) * 2019-01-28 2019-05-17 江苏关怀医疗科技有限公司 A kind of absorption type haemodialyser

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