CN205073372U - Compound blood purifying device - Google Patents
Compound blood purifying device Download PDFInfo
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- CN205073372U CN205073372U CN201520753317.2U CN201520753317U CN205073372U CN 205073372 U CN205073372 U CN 205073372U CN 201520753317 U CN201520753317 U CN 201520753317U CN 205073372 U CN205073372 U CN 205073372U
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Abstract
The utility model provides a compound blood purifying device, the device include outer cylinder and install at the internal interior cylinder of column jacket, outside in the axial of cylinder, and first end position in the outside of the first end of outer cylinder of interior cylinder, second end position in the inboard of the second end of outer cylinder of interior cylinder, first the serving of interior cylinder is equipped with first blood flow port, and the second of interior cylinder is served and is equipped with the filter screen, and the internal adsorbent that is equipped with of inner prop, be equipped with the dialyser between interior cylinder and the outer cylinder, be equipped with second blood flow port, dislysate entry and dislysate export on the perisporium of outer cylinder, in the axial of outer cylinder, dislysate entry and analyse the both ends that the liquid export lies in outer cylinder respectively, the first end of second blood flow port setting cylinder outside. The utility model provides a compound blood purifying device can reduce the use of pipeline, reduces treatment risk and treatment cost.
Description
Technical field
This utility model relates to medical instruments field, especially relates to a kind of for simultaneously to the compound apparatus for purifying blood of hemoperfusion and dialysis.
Background technology
Hemodialysis is a kind of new blood purification technology, has been widely used in the treatment of the diseases such as nephropathy, hepatopathy, acute poisoning.Hemodialysis is by the blood of patient from navigation inside the body to outside, is filtered, adsorbs, reach the object to blood purification by hemodialyzer to the small molecular toxin in blood.
As shown in Figure 1, existing a kind of hemodialyzer comprises cylinder 10, the two ends of cylinder 10 are respectively equipped with blood and flow into end 11 and blood outflow end 12, blood flows into end 11, blood outflow end 12 is threaded connection with the end of cylinder 10 respectively, and blood flows into end 11 and blood outflow end 12 sealed by blood port sealing cap 13,14 respectively.The perisporium of cylinder 10 is also provided with dialysis solution inlet side mouth 17 and dialysis solution outbound port 15, dialysis solution inlet side mouth 17 and dialysis solution outbound port 15 sealed by dialysis port sealing cap 18,16 respectively.Cylinder 10 inside is provided with dialyzer, utilize the principle of semipermeable membrane, the blood of patient and dialysis solution are introduced hemodialyzer simultaneously, both flow in opposite direction in the both sides of dialyzer, by the solute gradient of film both sides, osmotic gradient and hydraulic pressure gradient, remove to reach the moisture that in toxin and body, retention is too much, simultaneously required in added body material, and maintain the object of electrolyte and acid-base balance.
When treating, because blood has certain flow velocity, the blood of the blood entry port of hemodialyzer evenly cannot enter each root hollow-fibre membrane, cause blood to flow through in a large number being positioned at the dialyzer around blood mouth axial location, and the dialyzer being positioned at dialyser cylinder wall peripheral location because of blood throughput less, utilization rate is on the low side, causes the waste of dialyzer.And, due to the reason of production technology, in dialyser, bunchy tied up by dialyzer, especially space is less to be each other positioned at the dialyzer of dialyzer bundle core, more difficultly between dialysis solution with dialyzer fully to contact, thus cause the elimination efficiency of blood small molecular quantity of material on the low side, affect therapeutic effect.
In addition, carry out the patient Yi Yinfa complication of dialysis treatment for a long time, as symptoms such as hypertension, arthralgia, skin pruritus, so the clinical patient carrying out dialysing for a long time understands treating in conjunction with perfusion of discontinuity, thus get rid of long-term dialysis complication, improve the quality of living.Therefore, medical institutions generally adopt the hemodialyzer mode used of connecting with blood perfusion device to treat, and hemodialyzer is for removing the less material of blood middle-molecular-weihydroxyethyl, and blood perfusion device is for removing the larger material of blood middle-molecular-weihydroxyethyl.
But, hemodialyzer and the blood perfusion device Therapeutic Method used of connecting is used to need dedicated line to be connected hemodialyzer and blood perfusion device, more pipeline connection not only adds extracorporeal blood volume, also add the security risk in therapeutic process, too increase the consumption of the medical treatment consumptive materials such as pipeline simultaneously.
Summary of the invention
Main purpose of the present utility model is to provide a kind ofly can carry out hemodialysis and hemoperfusion, compound apparatus for purifying blood that Operative risk is lower simultaneously.
In order to realize above-mentioned main purpose, the compound apparatus for purifying blood that this utility model provides comprises outer cylindrical body and is arranged on the inner cylinder in outer cylindrical body, in outer cylindrical body axially, the first end of inner cylinder is positioned at the outside of the first end of outer cylindrical body, second end of inner cylinder is positioned at the inner side of the second end of outer cylindrical body, the first end of inner cylinder is provided with the first blood flow port, and the second end of inner cylinder is provided with filter screen, and inner cylinder is built with adsorbent; Between inner cylinder and outer cylindrical body, dialyzer is housed, the perisporium of the end cap of outer cylindrical body first end is provided with the second blood flow port, the end cap of outer cylindrical body second end is sealed end cap, the perisporium of outer cylindrical body is provided with dialysis solution entrance and dialysis solution outlet, in outer cylindrical body axially, dialysis solution entrance and analyse liquid outlet and lay respectively at the two ends of outer cylindrical body.
From such scheme, inner cylinder is built with adsorbent, between outer cylindrical body and inner cylinder, dialyzer is housed, and dialysis solution can flow in outer cylindrical body through dialysis solution entrance, when blood flows through inner cylinder, the larger toxin of the molecular weight in blood adsorb by adsorbent, realize the perfusion of blood, and the toxin of molecular weight is filtered by dialyzer through dialyzer at blood, realize the dialysis of blood.Therefore, compound apparatus for purifying blood can realize the function of hemoperfusion and hemodialysis simultaneously.And, blood flows to outer cylindrical body from inner cylinder or flows to inner cylinder from outer cylindrical body not to be needed through pipeline, but directly circulate from the position of inner cylinder and outer cylindrical body second end, external total blood volume can be greatly reduced like this, the risk for the treatment of reduces greatly, and reduce the use of pipeline consumptive material, reduce medical expense.
A preferred scheme is, the first blood port is blood entry port, and accordingly, the second blood port is blood outlet, or the first blood port is blood outlet, and accordingly, the second blood port is blood entry port.
When the first blood port is blood entry port, when second blood port is blood outlet, compound apparatus for purifying blood is the process of dialysing after first perfusion, when the first blood port is blood outlet, when second blood port is blood entry port, compound apparatus for purifying blood is the process of perfusion after first dialysing, and therefore compound apparatus for purifying blood can meet the needs of different therapeutic schemes, and adaptability is good.
Further scheme is, the two ends of dialyzer are fixed between the outer wall of inner cylinder and the inwall of outer cylindrical body by bonded adhesives, and the end cap of the first end of outer cylindrical body forms the first blood container cavity with the bonded adhesives of close first end and inner cylinder; The end cap of the second end of outer cylindrical body forms the second blood container cavity with near the bonded adhesives of the second end and the filter screen of inner cylinder second end; Dialysis solution container cavity is formed between bonded adhesives at outer cylindrical body two ends, inner cylinder, outer cylindrical body and dialyzer gap.
As can be seen here, bonded adhesives is used to be fixed at the two ends of dialyzer, dialyzer can be avoided to rock between inner cylinder and outer cylindrical body and curling, form ring-type etc., form blood container cavity and the dialysis solution container cavity of isolation simultaneously, blood can not directly be mixed with dialysis solution, can only dialyse through dialyzer, ensure that the safety and effectiveness of compound apparatus for purifying blood.
Further scheme is, the bonded adhesives of the second end near outer cylindrical body is obliquely installed relative to filter screen, and bonded adhesives tilts from the second end of outer cylindrical body to the first end of outer cylindrical body to the inwall of outer cylindrical body from the outer wall of inner cylinder.
Visible, when blood flows out to outer cylindrical body from inner cylinder, blood can rotate along bonded adhesives circumference and distribute ringwise, is conducive to blood and flows into equably in root dialyzer, guarantee that the contact of dialyzer and blood is more even, improve the utilization rate of dialyzer.
Further scheme is, is provided with through hole in the middle part of the end cap of the first end of outer cylindrical body, and the first end of inner cylinder is through through hole, and the inner peripheral of the outer wall of inner cylinder and through hole is tightly connected.
As can be seen here, inner cylinder is through the through hole on end cap, realize coordinating between inner cylinder with outer cylindrical body, and realize the connection between the inner peripheral of through hole and inner cylinder outer wall by sealing ring etc., avoid blood, dialysis solution from the gap leakage between inner cylinder and through hole.
Accompanying drawing explanation
Fig. 1 is the structure chart of existing a kind of hemodialyzer.
Fig. 2 is the structure chart of this utility model compound apparatus for purifying blood first embodiment.
Fig. 3 is the structure chart of this utility model compound apparatus for purifying blood second embodiment.
Below in conjunction with drawings and Examples, the utility model is described in further detail.
Detailed description of the invention
Compound apparatus for purifying blood of the present utility model can carry out perfusion and dialysis operation to blood simultaneously, and the sequencing of the dialysis of blood and perfusion can arrange according to the actual needs, meets the needs of different therapeutic scheme.
First embodiment:
See Fig. 2, the compound apparatus for purifying blood of the present embodiment has inner cylinder 31 and outer cylindrical body 40, and the diameter of inner cylinder 31 is less than the diameter of outer cylindrical body 40, and inner cylinder 31 is arranged in outer cylindrical body 40.Preferably, inner cylinder 31 and outer cylindrical body 40 are coaxially arranged.
In the present embodiment, the first end 32 of inner cylinder 31 is positioned at the lower end of Fig. 2, and first end 32 is provided with end cap 33, and end cap 33 is provided with blood mouth 35, and filter screen 34 is arranged between end cap 33 and inner cylinder 31.In the present embodiment, blood mouth 35 is blood entry port, namely the first blood flow port, and blood flows in compound apparatus for purifying blood from blood mouth 35.
Preferably, end cap 33 and inner cylinder 31 are achieved a fixed connection by screw thread couple, and end cap 34 can be integral type end cap, also can be split type end cap.If end cap 33 is integral type end cap, then the perisporium of end cap 33 is provided with female thread or external screw thread, and the perisporium of inner cylinder 31 is correspondingly provided with external screw thread or female thread, the threaded engagement on the screw thread of end cap 33 and inner cylinder 31 perisporium.If end cap 33 is split type end cap, then end cap 33 comprises a lid and nut, lid is arranged between inner cylinder 31 and nut, and nut is provided with female thread or external screw thread, by nut and being threaded thus realizing the connection between end cap 33 and inner cylinder 31 on inner cylinder 31.
Relative with first end 32 on inner cylinder 31 is the second end 36, the upper end namely in Fig. 2.Second end 36 of inner cylinder 31 is provided with filter screen 37, and filter screen 37 is fixed on the second end 36 of inner cylinder 31 by welding or the mode such as bonding.Between filter screen 34 and filter screen 37, adsorbent is housed, therefore adsorbent containment chamber 38 is formed between the filter screen 34 of inner cylinder 31 and filter screen 37, because filter screen 34 is less with the aperture of filter screen 37, adsorbent cannot through filter screen 34 and filter screen 37, filter screen 34 and filter screen 37 are set respectively at the two ends of inner cylinder 31, adsorbent can be avoided to flow to human body with blood.Absorption property is given full play in order to ensure the adsorbent in inner cylinder 31 in compound apparatus for purifying blood, adsorbent is avoided to unite, improve the mobility of blood in inner cylinder 31, avoid the hidden danger such as blood coagulation, inner cylinder 31 is for holding between the axial length of the container cavity of adsorbent is 1 times to 7 times of container cavity diameter, and namely the draw ratio D1 of inner cylinder 31 is 1<D1<7.
The first end 42 of outer cylindrical body 40 is the lower end shown in Fig. 2, and namely in outer cylindrical body 40 axially, the first end 42 of outer cylindrical body 40 is unidirectional one end with the first end 32 of inner cylinder 31.Further, in outer cylindrical body 40 axially, the first end 32 of inner cylinder 31 is positioned at the outside of outer cylindrical body 40, namely away from the side of the second end 36.Second end 43 of outer cylindrical body 40 and first end 42 being axially oppositely arranged in outer cylindrical body 40, and in outer cylindrical body 40 axially, the second end 36 of inner cylinder 31 is positioned at the inner side of the second end 43 of outer cylindrical body 40, namely near the side of first end 42.
Be provided with end cap 56 at the first end 42 of outer cylindrical body 40, in the axial direction, the middle part of end cap 56 has a through hole, and the first end 32 of inner cylinder 31 is through this through hole.The first end 42 of end cap 56 and outer cylindrical body 40 is connected by screw thread couple, buckle or the mode such as welding and being fixedly connected with.Ooze out in order to avoid blood between the outer wall of inner cylinder 31 and the inner peripheral of end cap 56, need to carry out encapsulation process to the outer wall of inner cylinder 31 and the inner peripheral of end cap 56, such as arrange the sealing ring 57 of annular, sealing ring 57 is arranged between the outer wall of inner cylinder 31 and the inner peripheral of end cap 56.Or, inner cylinder 31 is welded in the inner peripheral of end cap 56, or the perisporium of inner cylinder 31 is bonded in the inner peripheral of end cap 56.End cap 56 perisporium is radially provided with blood outlet 52.
Second end 43 of outer cylindrical body 40 is provided with sealed end cap 48, and the second end 43 of end cap 48 and outer cylindrical body 40 is by screw thread couple or the mode such as to weld and be fixedly connected with.Therefore, the second end 43 of outer cylindrical body 40 is not open design, can guarantee that blood can not flow out from the second end 43 of outer cylindrical body 40 like this.
Between inner cylinder 31 and outer cylindrical body 40, dialyzer is housed, one deck bonded adhesives 46,47 is formed respectively near the two ends place of outer cylindrical body 40, bonded adhesives 46,47 is for the two ends of fixing dialyzer, and in compound apparatus for purifying blood, isolation forms dialysis solution container cavity and blood container cavity simultaneously.Preferably, dialyzer is hollow-fibre membrane, can be made up of materials such as polyether sulfone, polysulfones, polypropylene.Preferably, use polyurethane AB glue as bonded adhesives.Dialyzer gap between the bonded adhesives 46,47 at outer cylindrical body 40 two ends and form dialysis solution container cavity 41 between inner cylinder 31 and outer cylindrical body 40; Blood container cavity is formed respectively between the end cap 56 of outer cylindrical body 40 first end and bonded adhesives 47, between the end cap 48 of outer cylindrical body 40 second end and bonded adhesives 46.The perisporium of outer cylindrical body 40 between bonded adhesives 46 and 47 is provided with dialysis solution entrance 50 and dialysis solution outlet 51, wherein dialysis solution entrance 50 is arranged near bonded adhesives 47 one end, dialysis solution outlet 51 is arranged near bonded adhesives 46 one end, and namely dialysis solution entrance 50 is all communicated with dialysis solution container cavity with dialysis solution outlet 51.
Blood outlet 52 is communicated with the blood container cavity that bonded adhesives 47 is formed with the end cap 56 of outer cylindrical body 40 first end; Inner cylinder 31 is communicated with the blood container cavity that bonded adhesives 46 is formed with the end cap 48 of outer cylindrical body 40 second end; Thus make the blood container cavity from entering the other end after blood mouth enters one end blood container cavity by the blood inner cylinder 31 along dialyzer inside, then discharge compound apparatus for purifying blood from blood outlet 52; And dialysis solution enters dialysis solution container cavity 41 from dialysis solution entrance 50, then export 51 discharges by dialysis solution, guarantee that the dialysis solution in dialysis solution container cavity 41 only circulates and can not enter in blood container cavity in dialysis solution container cavity; And the blood in blood container cavity also can not enter dialysis solution container cavity, ensure the effectiveness of compound apparatus for purifying blood.
Meet dialysis treatment needs in order to ensure the dialyzer in compound apparatus for purifying blood, outer cylindrical body 40 is less than 4 times of outer cylindrical body intracavity diameter for the axial length of the container cavity holding dialysis solution, and namely the draw ratio D2 of outer cylindrical body 40 is D2<4.
Be obliquely installed with filter screen 37 at the bonded adhesives 46 at the second end 43 place near outer cylindrical body 40, from the outer wall of inner cylinder 31 to the direction of the inwall of outer cylindrical body 40, bonded adhesives 36 tilts from the second end 43 of outer cylindrical body 40 to the first end 42 of outer cylindrical body 40, i.e. second end 43 of bonded adhesives 36 near one end of inner cylinder 31 more near outer cylindrical body 40, the first end 42 of bonded adhesives 36 near one end of outer cylindrical body 40 more near outer cylindrical body 40.Preferably, from the outer wall of inner cylinder 31 to the direction of the inwall of outer cylindrical body 40, bonded adhesives 46 is between 1 ° to 3 ° relative to the angle of filter screen 36 place plane.Like this, blood easily along the distribution of the annular radial of bonded adhesives 46, is conducive to blood and flows through each root dialyzer after flowing out from inner cylinder 31, improves the utilization rate of dialyzer.
In order to reach the object removing septicemia element preferably, select the dialyzer area of different size according to the difference of patient's condition, such as, area can be selected to be the dialyzer of the multiple different area specifications such as 1.2 square metres, 1.5 square metres, 1.7 square metres or 2.0 square metres.In addition, in order to meet the needs of blood purification, guaranteeing patient safety simultaneously, making the blood chamber vol in the extracorporeal circulation of patient be safety range, the adsorbent loading amount of inner cylinder 31 is 80 milliliters to 230 milliliters, preferably, selects 130 milliliters.
To load the Microporous resin adsorbent of 130 milliliters, the diameter that can design the adsorbent containment chamber of inner cylinder 31 is 40 millimeters, the wall degree in inner cylinder 31 adsorbent containment chamber is 2.5 millimeters, and the axial length in inner cylinder 31 adsorbent containment chamber should be 160 millimeters.Now, the internal diameter of outer cylindrical body 40 is 100 millimeters, and axial length is 150 millimeters, then dialyzer container cavity has enough spaces can hold 1.2 square metres, 1.5 square metres, 1.7 square metres, 2.0 square metres etc., therefore, the area of dialyzer can be between 1.2 square metres to 2.0 square metres.
Dialyzer can remove blood small molecular quantity of material, as the material that molecular weight is less than 10000, adsorbent resin can remove in macromolecule material, as the material that molecular weight is greater than 10000, both combine and can reach various toxin in full effect removing uremic patient body, remove the complication of carrying out dialysis treatment patient for a long time, improve the quality of life of patient.
Before using compound apparatus for purifying blood, need to rush process in advance, rushing liquid in advance enters compound apparatus for purifying blood from blood outlet flow 52, along gravity direction, first flow through dialyzer from the bottom up, enter adsorbent containment chamber 38 from top to bottom again, last menses mouth 35 flows out, thus while realizing that pre-punching is carried out to dialyzer and adsorbent, the fragment of adsorbent is gone out compound apparatus for purifying blood, avoid the adsorbent fragment in inner cylinder 31 to enter dialyzer, thus pollute dialyzer or affect the effectiveness of dialyzer.
When using the treatment of compound apparatus for purifying blood, blood enters adsorbent containment chamber 38 from blood entry port, and fully contacts with adsorbent, namely first carries out perfusion absorption.Blood after perfusion absorption flows into blood container cavity through filter screen 37, and then enters dialyzer and dialyse, and finally collects and near the blood container cavity of blood exit end, has blood to export and discharge.Because the polyurethane AB glue adhesive linkage as bonded adhesives 46 has certain gradient, so enable the blood of outflow inner cylinder 31 enter uniformly in dialyzer.Dialysis solution is divided into left and right two-way flowing after dialysis solution entrance 50 enters dialysis solution container cavity 45, is that rightabout flows in the vertical direction, namely flows from the bottom up along gravity direction, finally flow out in dialysis solution outlet 51 with blood.In the process, blood and dialysis solution are that rightabout flows and the exchange carrying out the material of small molecular amount, constitute a typical blood dialysis.In therapeutic process, along on gravity direction, blood flows into the top of inner cylinder 31 from the below of inner cylinder 31, and overflows from the top of inner cylinder 31 and enter dialyzer and carry out dialysis treatment.
Visible, compound apparatus for purifying blood can meet the object that patient carries out dialysis treatment and perfusion treatment simultaneously, and without the need to using pipeline to connect hemodialyzer and blood perfusion device, thus reduce the risk hidden danger caused due to increase extracorporeally circulating blood capacity and circulation distance, decrease the waste to medical treatment consumptive materials such as pipelines, energy-conserving and environment-protective.Simultaneously the operating procedure of medical personnel also simplifies, and has saved the labour force of medical personnel, has reduced the requirement to medical personnel, avoids the risk caused due to pipeline wrong etc.
When making compound apparatus for purifying blood, can perform according to following steps:
(1) installation mold: the outer cylindrical body 40 inner cylinder 31 of open at both ends being placed in open at both ends is inner, dialyzer is distributed in uniformly in the dialyzer container cavity 41 between outer cylindrical body 40 and inner cylinder 31, and one end of inner cylinder 31 and outer cylindrical body 40 is fixed on end-sealing die, then the other end of inner cylinder 31 and outer cylindrical body 40 is fixed with second end-sealing die.Wherein, the end that inner cylinder 31 is arranged at the inner one end of outer cylindrical body 40 is provided with sealing plug, avoids polyurethane AB glue in manufacturing process to enter inner cylinder 31 inner.In addition, inner cylinder 31 stretches out the inner one end of outer cylindrical body 40 and is provided with similar sealing plug equally.
(2) centrifugal injecting glue: the outer cylindrical body 40 installing inner cylinder 31 is fixed in centrifuge, injected rubber hose is inserted dialysis solution gateway, start centrifuge, between ectonexine cylinder, inject polyurethane AB glue, when polyurethane AB adhesive curing is to predetermined hardness, remove the end-sealing die at two ends.
(3) glue face is cut: take out sealing plug, the lower end of bale splitter to the polyurethane AB glue after solidification is used to carry out plane rough lumber, until all fibres all unobstructed after, carry out essence and be switched to predetermined gradient, locate stopping cut glue when the distance of polyurethane AB glue and outer cylindrical body 40 is 2 millimeters to 3 millimeters, what complete lower surface cuts glue.
(4) gluing face is cut: use bale splitter to carry out plane rough lumber to this device upper end, locate to stop rough lumber when the distance of polyurethane AB glue and inner cylinder 31 is 2 millimeters to 3 millimeters, start to carry out accurate annular cutting around internal layer cylinder, locate stopping cut glue until the distance of polyurethane AB glue and outer cylindrical body 40 is 2 millimeters to 3 millimeters, what complete upper surface cuts glue.
(5) just assemble: by modes such as welding, the filter screen 37 of the second end 36 being positioned at inner cylinder 31 is loaded inner cylinder 31, the end cap 48 that then installation of outer cylindrical body 40 second end is sealed.
(6) resin subpackage: the adsorbent loading ormal weight in inner cylinder 31, is then positioned at the filter screen 34 of inner cylinder 31 first end 32, is then loaded onto by the end cap 33 of inner cylinder 31 first end 32, and is loaded onto by the end cap 56 of outer cylindrical body 40 first end 42.Now, need to use sealing ring 57 to be sealed by the inner peripheral of the outer wall of inner cylinder 31 and end cap 56.
(7) add water: export 52 from blood and enter water for injection, then enter dialyzer through blood container cavity, then after the blood container cavity converging to the other end, flow in adsorbent containment chamber 38 through filter screen 37, finally flow out from blood mouth 35.Because water for injection enters compound apparatus for purifying blood from blood outlet 52, adsorbent containment chamber 38 is flowed through again through dialyzer, menses mouth 35 flows out again, thus the water for injection ensureing to flow through dialyzer is the clean water for injection not with microgranule, and the adsorbent fragment in adsorbent containment chamber 38 flows out from blood mouth 35 and do not pollute dialyzer, ensure the quality of product.
(8) sterilizing: the compound apparatus for purifying blood adding water qualified is assembled, packed, then carries out sterilization treatment.
Owing to using centrifuge injection polyurethane AB glue to form bonded adhesives 46,47, thus easily dialyzer is fixed between inner cylinder 31 and outer cylindrical body 40, and dialyzer is evenly distributed, and is conducive to the utilization rate improving dialyzer.
Second embodiment:
See Fig. 3, the compound apparatus for purifying blood of the present embodiment has inner cylinder 60 and is positioned at the outer cylindrical body 70 outside inner cylinder 60, and inner cylinder 60 and outer cylindrical body 70 coaxial line are arranged.In outer cylindrical body 70 axially, the first end 61 of inner cylinder 60 is positioned at the outside of outer cylindrical body 70 first end 71, and the second end 62 of inner cylinder 60 is positioned at the inner side of outer cylindrical body 70 second end 72.The first end 61 of inner cylinder 60 is provided with filter screen 64 and end cap 65, and end cap 65 is provided with blood mouth 66, and blood mouth 66 is the blood outlet of the present embodiment, and namely the first blood flow port, blood flows out compound apparatus for purifying blood from blood mouth 66.Second end 62 of inner cylinder 60 is provided with filter screen 67, and in outer cylindrical body 70 axially, filter screen 67 is positioned at the inner side of inner cylinder 60 second end 62, namely filter screen 67 than the end wall of inner cylinder 60 closer to the first end 61 of inner cylinder 60.Between the filter screen 64 at inner cylinder 60 two ends and filter screen 67, adsorbent is housed, therefore forms adsorbent containment chamber 63 in inner cylinder 60.
The first end 71 of outer cylindrical body 70 is provided with end cap 84, the middle part of end cap 84 has a through hole, the first end 61 of inner cylinder 60 is through this through hole, between the outer wall and the inner peripheral of end cap 84 of inner cylinder 60, be provided with sealing ring 85, go out from the gap seepage between the outer wall and the inner peripheral of end cap 84 of inner cylinder 60 to avoid blood.Second end 72 of outer cylindrical body 70 has sealed end cap 76, avoids blood to flow out compound apparatus for purifying blood from the second end 72.
Dialyzer is provided with between inner cylinder 60 and outer cylindrical body 70, one deck bonded adhesives 77,78 is formed respectively at the two ends place near outer cylindrical body 70, bonded adhesives 77,78 is for the two ends of fixing dialyzer, and in compound apparatus for purifying blood, isolation forms dialysis solution container cavity and blood container cavity simultaneously.Further, bonded adhesives 77,78 is formed between the outer wall of inner cylinder 60 and the inwall of outer cylindrical body 70, therefore, forms dialyzer container cavity 73 between the outer wall of inner cylinder 60 and the inwall of outer cylindrical body 70.
Dialyzer gap between the bonded adhesives 77,78 at outer cylindrical body 70 two ends and form dialysis solution container cavity between inner cylinder 60 and outer cylindrical body 70; Form blood container cavity 75 between the end cap 84 of outer cylindrical body 70 first end and bonded adhesives 77, between the end cap 76 of outer cylindrical body 40 second end and bonded adhesives 78, form another blood container cavity.
The perisporium of outer cylindrical body 70 between bonded adhesives 77,78 is provided with dialysis solution entrance 81 and dialysis solution outlet 82, in outer cylindrical body 70 axially, dialysis solution entrance 81 is arranged near bonded adhesives 78 one end, dialysis solution outlet 82 is arranged near bonded adhesives 78 one end, dialysis solution flows into dialysis solution container cavity 73 from dialysis solution entrance 81, and flows out through dialysis solution outlet 82.Outer cylindrical body 70 is also provided with the blood entry port 83 as the second blood flow port on the perisporium of the end cap of first end 71, and blood flows into outer cylindrical body 70 from blood entry port 83.
Visible, compound apparatus for purifying blood in this embodiment is the device of re perfusion of first dialysing, namely during treatment, blood enters blood after blood container cavity 75 from the blood entry port 83 outer cylindrical body 70 and can be distributed to uniformly in dialyzer along annular bonded adhesives 77, enter the blood container cavity of the other end through dialyzer, then by adsorbent, the noxious substance in blood is adsorbed by inner cylinder 60; Dialysis solution then flows into dialyser container cavity from dialysis solution entrance 81, then exports outflow by dialysis solution, and blood and dialysis solution are that rightabout flows and the exchange carrying out the material of small molecular amount, constitute a typical blood dialysis.Carrying out hemoperfusion to enable the blood flowed out in dialyzer flow into preferably in inner cylinder 60, in inner cylinder 60, be designed with horn-like deflector 79 near end cap 76 one end, and filter screen 67 being arranged in deflector 79.Over the course for the treatment of, dialysis solution in dialysis solution container cavity only circulates and can not enter in the blood container cavity at two ends in dialysis solution container cavity, the blood flowing into the blood container cavity of outer cylindrical body 70 lower end also can not flow into dialysis solution container cavity, thus ensure that the safety and effectiveness of this apparatus for purifying blood.
The compound apparatus for purifying blood of the present embodiment carries out pre-process of rushing and is basically the same as those in the first embodiment, and repeats no more.The manufacture method of the compound apparatus for purifying blood of the present embodiment is substantially identical with the manufacture method of the first embodiment, repeats no more.
Apply compound apparatus for purifying blood of the present utility model can carry out perfusion, dialysis simultaneously operation to blood, toxin larger for blood middle-molecular-weihydroxyethyl is carried out adsorbing and filtering the toxin of molecular weight simultaneously, patient body outer tube is avoided to pass by long problem, greatly reduce the risk for the treatment of, also reduce treatment cost.
Finally it is emphasized that this utility model is not limited to above-mentioned embodiment, the change etc. as the change of dialyzer area, inner cylinder and outer cylindrical body draw ratio change also should be included in this utility model claim protection domain in.
Claims (10)
1. compound apparatus for purifying blood, is characterized in that: comprise
Outer cylindrical body and the inner cylinder be arranged in described outer cylindrical body, in described outer cylindrical body axially, the first end of described inner cylinder is positioned at the outside of the first end of described outer cylindrical body, second end of described inner cylinder is positioned at the inner side of the second end of described outer cylindrical body, the first end of described inner cylinder is provided with the first blood flow port, second end of described inner cylinder is provided with filter screen, and described inner cylinder is built with adsorbent;
Between described inner cylinder and described outer cylindrical body, dialyzer is housed, the perisporium of the end cap of described outer cylindrical body first end is provided with the second blood flow port, the end cap of described outer cylindrical body second end is sealed end cap, the perisporium of outer cylindrical body is provided with dialysis solution entrance and dialysis solution outlet, in described outer cylindrical body axially, described dialysis solution entrance and the outlet of described dialysis solution lay respectively at the two ends of described outer cylindrical body.
2. compound apparatus for purifying blood according to claim 1, is characterized in that:
Described first blood port is blood entry port, and described second blood port is blood outlet.
3. compound apparatus for purifying blood according to claim 1, is characterized in that:
Described first blood port is blood outlet, and described second blood port is blood entry port.
4. compound apparatus for purifying blood according to claim 1 and 2, is characterized in that:
The two ends of described dialyzer are fixed between the outer wall of described inner cylinder and the inwall of described outer cylindrical body by bonded adhesives;
The end cap of the first end of described outer cylindrical body forms the first blood container cavity with the bonded adhesives of close first end and inner cylinder; The end cap of the second end of described outer cylindrical body forms the second blood container cavity with near the bonded adhesives of the second end and the filter screen of described inner cylinder second end; Dialysis solution container cavity is formed between bonded adhesives at described outer cylindrical body two ends, described inner cylinder, described outer cylindrical body and described dialyzer gap.
5. compound apparatus for purifying blood according to claim 4, is characterized in that:
The described bonded adhesives of the second end near described outer cylindrical body is obliquely installed relative to described filter screen, and described bonded adhesives tilts from the second end of described outer cylindrical body to the first end of described outer cylindrical body to the inwall of described outer cylindrical body from the outer wall of described inner cylinder.
6. compound apparatus for purifying blood according to claim 3, is characterized in that:
Second end of described inner cylinder is provided with horn-like deflector, and described filter screen is arranged in described deflector, and in described outer cylindrical body axially, described filter screen is positioned at the inner side of the second end of described inner cylinder.
7. the compound apparatus for purifying blood according to any one of claims 1 to 3, is characterized in that:
Be provided with through hole in the middle part of the end cap of the first end of described outer cylindrical body, the first end of described inner cylinder is through described through hole, and the inner peripheral of the outer wall of described inner cylinder and described through hole is tightly connected.
8. the compound apparatus for purifying blood according to any one of claims 1 to 3, is characterized in that:
Described outer cylindrical body length is less than 4 times of the diameter of described outer cylindrical body, between described inner cylinder length is 1 times to 7 times of the diameter of described outer cylindrical body.
9. the compound apparatus for purifying blood according to any one of claims 1 to 3, is characterized in that:
The in-built adsorbent capacity of described inner cylinder is between 80 milliliters to 230 milliliters.
10. the compound apparatus for purifying blood according to any one of claims 1 to 3, is characterized in that:
The dialyzer area filled between described inner cylinder and outer cylindrical body is between 1.2 square metres to 2.0 square metres.
Priority Applications (1)
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105343954A (en) * | 2015-09-25 | 2016-02-24 | 珠海健帆生物科技股份有限公司 | Composite blood purifying device and manufacturing method thereof |
| CN108245723A (en) * | 2016-12-28 | 2018-07-06 | 于杰 | Integrated blood purification |
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2015
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105343954A (en) * | 2015-09-25 | 2016-02-24 | 珠海健帆生物科技股份有限公司 | Composite blood purifying device and manufacturing method thereof |
| CN105343954B (en) * | 2015-09-25 | 2018-03-06 | 珠海健帆生物科技股份有限公司 | Compound apparatus for purifying blood and preparation method thereof |
| CN108245723A (en) * | 2016-12-28 | 2018-07-06 | 于杰 | Integrated blood purification |
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Address after: 519080 Zhuhai hi tech Zone No. six road, Guangdong Province, 98 Patentee after: Jianfan Biotechnology Group Co., Ltd. Address before: 519080 Zhuhai hi tech Zone No. six road, Guangdong Province, 98 Patentee before: Jafron Biomedical Co., Ltd. |
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