CN109568700A - A kind of blood separation dental unit complete machine - Google Patents

A kind of blood separation dental unit complete machine Download PDF

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Publication number
CN109568700A
CN109568700A CN201811489848.XA CN201811489848A CN109568700A CN 109568700 A CN109568700 A CN 109568700A CN 201811489848 A CN201811489848 A CN 201811489848A CN 109568700 A CN109568700 A CN 109568700A
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CN
China
Prior art keywords
blood
pinching
complete machine
pump
detector
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CN201811489848.XA
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Chinese (zh)
Inventor
曾庆松
包奕强
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Chengdu Chuanghefeng Biotechnology Co Ltd
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Chengdu Chuanghefeng Biotechnology Co Ltd
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Priority to CN201811489848.XA priority Critical patent/CN109568700A/en
Publication of CN109568700A publication Critical patent/CN109568700A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3627Degassing devices; Buffer reservoirs; Drip chambers; Blood filters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3639Blood pressure control, pressure transducers specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/369Temperature treatment

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

The present invention relates to medical instruments fields, disclose a kind of blood separation dental unit complete machine, including rack, anticoagulant pump, blood pump, blood plasma pump, anti-coagulants hanger, physiological saline hanger, centrifuge, pipeline detector, therapeutic equipment clip, several pressure detectors, several Ultrasonic Wave Air Detectors and several pinching valves are installed in the rack;The centrifuge is located at frame central position, is provided with the blood pump and pipeline detector by centrifuge;The anti-coagulants hanger and physiological saline hanger are mounted on the two sides of rack.Blood is separated haematoblast and blood plasma using centrifugation technique with the separate cup cooperation in purification system using centrifuge by the present invention, instead of with UF membrane blood, substantially reduces production cost;And the functional components such as heater, cuff connector, electronic scale, heat-sealing device are integrated with, medical worker is facilitated to operate with.

Description

A kind of blood separation dental unit complete machine
Technical field
The present invention relates to medical instruments fields, and in particular to a kind of blood separation dental unit complete machine.
Background technique
Blood purification therapy is the clinic application developed by technologies such as haemodialysis, bloodletting threapies, 20 Th century later has obtained quick development, becomes treatment method indispensable in clinical practice.
The blood purification dress that blood purification system generally includes extracorporeal circulation pipeline and is connected in the extracorporeal circulation pipeline It sets, extracorporeal circulation pipeline includes blood stream outlet pipeline and blood stream return pipe road.During blood purification treatment, pass through blood It flows out pipeline and blood is drawn into human body, after the purification of apparatus for purifying blood, by the defeated the Huis' body in blood stream return pipe road, to reach Remove the substances such as virulence factor in blood.
Core technology in blood purification therapy is the separation of blood constituent, currently, the isolation technics of mainstream has centrifugation point From technology, membrane separation technique and adsorption separation technology.
Wherein membrane separation technique, product is that manufactured filter is filled using the hollow-fibre membrane of certain pore size size, right The substance of different molecular weight is separated, and common filter has haemodialyser, plasma separator and cascadeflow.Film Isolation technics has many advantages, such as that separative efficiency height, electrolyte balance can easily be accommodated.But there are relative specificities for membrane separation technique not Enough, the shortcomings that target substance of different molecular weight size, different hydrophilic properties cannot be taken into account;And to be repeated Treatment, not only increases treatment cost, also drastically reduces the tolerance of patient.
Adsorption separation technology is that adsorbent is filled into absorber, and disposable aseptic medical equipment is made, then Blood is drawn from human body, by adsorption column in a manner of blood perfusion or plasma perfusion, is inhaled to specific or relative specificity A kind of mode of action of attached one of or several morbid substances, once property uses blood perfusion device, one to common absorber Secondary property uses Endotoxin adsorption device, disposable plasma bilirubin absorber, DNA immunization adsorption column, blood lipid adsorption column, white thin Born of the same parents' adsorption column etc..Adsorption separation technology is excellent with the adsorbing separation and removal that can form relative specificity to target substance Point, but there are electrolyte balances to be difficult to the shortcomings that adjusting for adsorbing separation.
For some diseases, morbid substance material composition usually different by several properties is very up to several Hundred kinds, this is to being used alone should bringing the morbid substance that separates in blood constituent and separated plasma for a certain isolation technics Challenge.Therefore, the advantages of centrifuge separation, UF membrane and adsorption separation technology capable of being combined, comprehensively utilizing three, always It is the important research direction of this field.
Now dental unit complete machine is separated without the blood for centrifugal separation technology currently on the market.
Summary of the invention
Dental unit complete machine is separated using blood the purpose of the present invention is to provide a kind of, utilizes centrifugal separation technology point From blood, cooperate blood component separation and multiple adsorption system or the blood component separation of blood plasma molecule and blood plasma molecule multiple net Change system uses, and purifies haemodialysis disease.Centrifugal blood separation, plasma purification aspect especially for artificial liver in treatment Blood separate dental unit complete machine.
To achieve the above object, the invention provides the following technical scheme:
A kind of blood separates dental unit complete machine, including rack, which is characterized in that be equipped in the rack anticoagulant pump, Blood pump, blood plasma pump, anti-coagulants hanger, physiological saline hanger, centrifuge, pipeline detector, therapeutic equipment clip, several pressure are visited Survey device, several Ultrasonic Wave Air Detectors and several pinching valves;The centrifuge is located at frame central position, setting by centrifuge There are the blood pump and pipeline detector;The anti-coagulants hanger and physiological saline hanger are mounted on the two sides of rack.
Further, the pressure detector includes first pressure detector, second pressure detector, the spy of third pressure Survey device.
Further, the Ultrasonic Wave Air Detector includes the first, second to the 5th Ultrasonic Wave Air Detector.
Further, the pinching valve includes the first, second to the 7th pinching valve.
Further, the therapeutic equipment clip includes at least first order therapeutic equipment clip and second level therapeutic equipment clip.
In the present invention, the universal wheel mobile convenient for complete machine is installed below the rack.
In the present invention, the heating for keeping blood plasma return line or blood backflow pipeline constant temperature is installed in the rack Device, the heater are consistent the blood plasma of purification or the temperature of blood with human body temperature, patient are allowed to feel more comfortable.
In the present invention, the cuff connector for cuff is installed in the rack, it can be to cuff by cuff connector Punching deflation is carried out, real time monitoring human blood-pressure is monitored in real time or prompted by device sensor.
In the present invention, the electronic scale for weighing blood plasma is also equipped in the rack, the electronic scale is in sampled plasma When, collected blood plasma weight can be weighed in real time.
Heat-sealing device is installed in heretofore described rack, plasma bags can be sealed immediately after sampled plasma is good, side Just transfer transport.
The operation principle of the present invention is that:
Compared with prior art, the beneficial effects of the present invention are:
Blood is separated haematoblast using centrifugation technique with the separate cup cooperation in purification system using centrifuge by the one, present invention And blood plasma, instead of with UF membrane blood, real blood plasma separating effect is more thorough, and it reduces red blood cell mixed volume and improves therapeutic effect, Production cost is substantially reduced simultaneously;
The two, present invention are cooperated using pump line in anticoagulant pump, blood pump, blood plasma pump and purification system, and pump line is in anticoagulant pump, blood It is that anti-coagulants, physiological saline, blood haemocyte etc. provide power that flowing, which squeezes, on liquid pump, blood plasma pump, helps anti-coagulants, physiology salt Water, blood, blood plasma, haemocyte flow in circulation line in vitro;
Three, present invention design has pressure detector, and the pressure detector connector cooperation in pressure detector and purification system can Pressure value in real-time detection extracorporeal circulation pipeline, judge whether purification system abnormal using pressure value and judge patient itself Whether hyperpiesia or too low situation are occurred;
Four, present invention design has Ultrasonic Wave Air Detector, Ultrasonic Wave Air Detector real-time detection real-time detection extracorporal circulatory system Whether contain air in pipeline, unexpected generation can be effectively prevent.
The five, present invention design having heaters, and heater heats the one section of blood plasma or blood in extracorporeal circulation pipeline close to human body The temperature of liquid return line, the blood plasma or blood that make purification is consistent with human body temperature, and patient is allowed to feel more comfortable.
The six, present invention design have heat-sealing device, sampled plasma it is good after plasma bags can be sealed immediately, facilitate transfer fortune It is defeated.
Detailed description of the invention
Fig. 1 is the structural diagram of the present invention;
Fig. 2 is right view of the invention;
Appended drawing reference: 1 is the first Ultrasonic Wave Air Detector, 2 be the second Ultrasonic Wave Air Detector, 3 is first filter card Hoop, 4 be first pressure detector, 5 be centrifuge, 6 be third Ultrasonic Wave Air Detector, 7 be heater, 8 be cuff connector, 9 it is blood pump, 10 be anti-coagulants hanger fixing piece, 11 be third filter clip, 12 be third pressure detector, 13 is the 4th Ultrasonic Wave Air Detector, 14 be the 5th Ultrasonic Wave Air Detector, 15 be anticoagulant pump, 16 be retaining clip for pipelines, 17 be aobvious Display screen, 18 be blood plasma pump, 19 be the first pinching valve, 20 be the second pinching valve, 21 be third pinching valve, 22 be the 4th pinching valve, 23 be electronic scale, 24 be pipeline detector, 25 be the 5th pinching valve, 26 be the 6th pinching valve, 27 be the 7th pinching valve, 28 be heat Clutch, 29 be plasma bags clothes-hook, 30 be rack, 31 be universal wheel, 32 be waste fluid bag clothes-hook, 33 be first order therapeutic equipment clip, 34 be second level therapeutic equipment clip, 35 be the second filter clip, 36 be second pressure detector, 37 be physiological saline hanger peace Piece installing, 38 are physiological saline hanger.
Fig. 3 is the first mating consumptive material schematic diagram;
Appended drawing reference are as follows: a1 is anti-coagulants pump line, is third air detectors detection position at b1, at c1 is the first air detectors Position is detected for the second air detectors at detection position, d1, e1 is first filter, f1 is first pressure detector connector, g1 Place is at the first pinching, at h1 be at the second pinching, at i1 is that the 4th air detectors detect position, j1 is blood pump line, k1 is Pipeline detector detection position, at l1 to be at third pinching, at m1 be at the 4th pinching, n1 is blood plasma pump line, o1 is the second filtering Device, p1 be second pressure detector connector, at q1 be primary treatment device, r1 is secondary treatment device, at s1 be at the 5th pinching, At t1 at the 6th pinching, u1 be third filter, v1 is third pressure detector connector, at w1 is the 5th air detectors It is that heater heats position, z1 is Centrifuge Cup at detection position, x1.
Fig. 4 is second of mating consumptive material schematic diagram;
Attached drawing 4 marks are as follows: a2 is anti-coagulants pump line, is third air detectors detection position at b2, at c2 is the first air detection Device detection position, the place d2 be the detection of the second air detectors position, e2 be first filter, f2 be first pressure detector connector, At g2 at the first pinching, be at the second pinching, at i2 at h2 be that the 4th air detectors detect position, j2 is blood pump line, k2 Position is detected for pipeline detector, at l2 to be at third pinching, at m2 be at the 4th pinching, n2 is blood plasma pump line, o2 is the second mistake Filter, p2 be second pressure detector connector, at q2 be primary treatment device, r2 is secondary treatment device, at s2 is the 5th pinching Place, the place t2 be at the 6th pinching, at w2 is the 5th air detectors detect position, at x2 be heater heating position, z2 is Centrifuge Cup.
Fig. 5 is the third mating consumptive material schematic diagram;
Attached drawing 5 marks are as follows: a3 is anti-coagulants pump line, is third air detectors detection position at b3, at c3 is the first air detection Device detection position, the place d3 be the detection of the second air detectors position, e3 be first filter, f3 be first pressure detector connector, At g3 at the first pinching, be at the second pinching, at i3 at h3 be that the 4th air detectors detect position, j3 is blood pump line, k3 Position is detected for pipeline detector, at l3 to be at third pinching, at m3 be at the 4th pinching, n3 is blood plasma pump line, o3 is the second mistake Filter, p3 be second pressure detector connector, at q3 be primary treatment device, r3 is secondary treatment device, at s3 is the 5th pinching Place, the place t3 be at the 6th pinching, at w3 is the 5th air detectors detect position, be heater heating position at x3, at y3 be the 7th At pinching, z3 be Centrifuge Cup.
Fig. 6 is the 4th kind of mating consumptive material schematic diagram;
Attached drawing 6 marks are as follows: a4 is anti-coagulants pump line, is third air detectors detection position at b4, at c4 is the first air detection Device detection position, the place d4 be the detection of the second air detectors position, e4 be first filter, f4 be first pressure detector connector, At g4 at the first pinching, be at the second pinching, at i4 at h4 be that the 4th air detectors detect position, j4 is blood pump line, k4 Position is detected for pipeline detector, at l4 to be at third pinching, at m4 be at the 4th pinching, n4 is blood plasma pump line, o4 is the second mistake Filter, p4 be second pressure detector connector, at q4 be primary treatment device, r4 is secondary treatment device, at s4 is the 5th pinching Place, the place t4 are at the 6th pinching, u4 is third filter, v4 is third pressure detector connector, at w4 is the 5th air Detector detection position, the place x4 are that heater heats position, is at the 7th pinching, z4 is Centrifuge Cup at y4.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other Embodiment shall fall within the protection scope of the present invention.
One blood of embodiment separates the combination of dental unit complete machine Fig. 1, Fig. 2 and Fig. 3 respectively with regard to the installation of consumptive material and equipment Operational process be illustrated
The installation of consumptive material:
Setting agent pump pipe a1 is installed in anticoagulant pump 15, and third air detectors detect position b1 by the 5th Ultrasonic Wave Air Detector 14 detections, which check, whether there is air or bubble in anti-coagulants pipeline, the first air detectors detect position c1 by the first ultrasonic wave Air detectors 1, which detect, whether there is air or bubble in pipeline, the second air detectors detect position d1 by the second ultrasonic wave Air detectors 2, which detect, whether there is air or bubble in pipeline, first filter e1 is mounted on first filter clip 3 On, the first pressure detector connector f1 connecting with first filter e1 is mounted on first pressure detector 4, the first pinching Place g1 is clamped by the 7th pinching valve 27, and h1 is clamped by the 6th pinching valve 26 at the second pinching, and the 4th air detectors detect position i1 Being detected by third Ultrasonic Wave Air Detector 6 whether there is air or bubble in pipeline, blood pump line j1 is mounted on blood pump 9 On, separate cup z1 is mounted in centrifuge 5, and pipeline detector detection position k1 is detected by pipeline detector 24, l1 at third pinching Clamped by the 4th pinching valve 22, plasma bags are hung on electronic scale 23, at the 4th pinching m1 clamped by third pinching valve 21, blood plasma pump Pipe n1 is mounted in blood plasma pump 18, and the second filter o1 is mounted on the second filter clip 35, the connection of second pressure detector Head p1 is plugged on second pressure detector 36, and primary treatment device q1 is mounted on first order therapeutic equipment clip 32, secondary treatment Device r1 is mounted on second level therapeutic equipment clip 33, and s1 is clamped by the second pinching valve 20 at the 5th pinching, at the 6th pinching t1 by First pinching valve 19 is clamped, and third pressure detector connector v1 is plugged on third pressure detector 12, third filter u1 It is mounted on third filter clip 11, the 5th air detectors detect position w1 by 13 return pipe of the 4th Ultrasonic Wave Air Detector It whether there is air or bubble in road, the pipeline of heater heating position x1 is put into heater 7, makes the blood plasma or blood of purification Temperature be consistent with human body temperature, allow patient to feel more comfortable.
5th pinching valve 25 is reserved spare, and heat-sealing device 28, plasma bags clothes-hook 29 and 32 integrated installation of waste fluid bag clothes-hook are in machine On frame 30, medical worker is facilitated to operate with.Heat seal is tamping the sebific duct in plasma bags, blood after the heat-sealing device is used for sampled plasma Slurry immediately can seal plasma bags after being collected, and transfer is facilitated to transport.
Equipment running process:
Cooperate attached drawing 1, Fig. 2, Fig. 3 is explained.Mating consumptive material operation machine is first installed, at this time in addition to the second pinching valve 20 is beaten It opens, remaining pinching valve is in closed state, according to prompt, opens the 4th hemostatic clamp, opens the 7th hemostatic clamp, use physiological saline Primary treatment device q1, secondary treatment device r1 are rinsed, or syntagmatic is opened and closed come single by the 5th hemostatic clamp and the 6th hemostatic clamp Primary treatment device and secondary treatment device are solely rinsed, the liquid after flushing enters waste fluid bag, after the completion of flushing, closes the 5th hemostasis Folder closes the 6th hemostatic clamp, closes the 7th hemostatic clamp, the cuff being connected at cuff interface 8 is tied to people according to machine prompts Human blood-pressure monitoring is carried out at body blood collecting arms, at this point, the first pinching valve 19 is closed, the second pinching valve 20 is closed, third pinching Valve 21 is opened, and the 4th pinching valve 22 is closed, and the 5th pinching valve 25 is closed, and the 6th pinching valve 26 is opened, and the 7th pinching valve 27 is opened, Centrifuge 5 starts running.Then human vas puncture is carried out, blood of human body enters machine hemostix, opens the first hemostatic clamp, together When blood pump 9 and anticoagulant pump 15 start according to set proportion clockwise operation, whole blood is in blood pump 9 at Fig. 4 expression Effect is lower to be started to open the second hemostatic clamp to external flowing, and whole blood enters the bag that keeps sample, in case subsequent blood detection is used, has kept sample At the second hemostatic clamp of rear closing, blood is passed sequentially through as the first Ultrasonic Wave Air Detector position c1, the second ultrasonic wave air detection Device position d1, first filter e1, the 7th pinching valve position g1, the 4th air detectors detect position i1, blood pump line j1, Centrifuge Cup Z1, according to iuntercellular difference of specific gravity, centrifugation separates blood plasma and haemocyte, and the blood plasma isolated enters plasma bags, pipeline detector 24, monitor pipeline inner cell composition in real time, the second folder when finding that blood plasma and red blood cell interface reach pipeline 24 position of detector Only valve 20 open, centrifuge 5 is out of service, and blood pump 9 rotates counterclockwise, equipment start feed back Centrifuge Cup z1 in haemocyte to Human body, haemocyte passes sequentially through blood pump line j1 at this time, and the 4th air detectors detect position i1, the 7th pinching valve position g1, and first Filter e1 monitors the blood of the Huis' body in real time since first pressure detector connector f1 is connected on first pressure detector 4 Pressure, haemocyte pass sequentially through the second Ultrasonic Wave Air Detector position d1, the first Ultrasonic Wave Air Detector position c1, machine blood sampling Needle, Hui Renti.It feeds back blood plasma pump 18 simultaneously to start to work, blood plasma flows through the second filter o1, second pressure detector connector P1, since second pressure detector connector p1 is connected in blood plasma pressure monitor shown in Fig. 2 36, so real time monitoring blood Slurry enters the blood plasma pressure value before primary treatment device q1, and blood plasma passes sequentially through primary treatment device q1, secondary treatment device r1, the 6th folder Only locate t1, third filter u1, third pressure detector connector v1 is connected on third pressure detector 12, monitors in real time back The blood plasma pressure value of defeated human body, blood plasma detect position w1 followed by the 5th air detectors, and heater heats position x1, blood transfusion apparatus group Part, last the Huis' body.
Two blood of embodiment separates the combination of dental unit complete machine Fig. 1, Fig. 2 and Fig. 4 respectively with regard to the installation of consumptive material and equipment Operational process be illustrated:
The installation of consumptive material:
Setting agent pump pipe a2 is installed in anticoagulant pump 15, and third air detectors detect position b2 by the 5th Ultrasonic Wave Air Detector 14 detections, which check, whether there is air in anti-coagulants pipeline, the first air detectors detect position c2 by the first ultrasonic wave air detection Device 1, which detects, whether there is air or bubble in pipeline, the second air detectors detect position d2 by the second ultrasonic wave air detection Device 2, which detects, whether there is air or bubble in pipeline, first filter e2 is mounted on first filter clip 3, with first The first pressure detector connector f2 of filter e2 connection is mounted on first pressure detector 4, and g2 is by the first pinching Seven pinching valves 27 are clamped, and h2 is clamped by the 6th pinching valve 26 at the second pinching, and the 4th air detectors detection position i2 is surpassed by third Sound wave air detectors 6, which detect, whether there is air or bubble in pipeline, blood pump line j2 is mounted on blood pump, separate cup Z2 is mounted in centrifuge 5, and pipeline detector detection position k2 is detected by pipeline detector 24, and l2 is by the 4th pinching at third pinching Valve 22 is clamped, and plasma bags are hung on electronic scale 23, and m2 is clamped by third pinching valve 21 at the 4th pinching, blood plasma pump line n2 is mounted on In blood plasma pump 18, the second filter o2 is mounted on the second filter clip 35, and second pressure detector connector p2 is plugged on On second pressure detector 36, primary treatment device q2 is mounted on first order therapeutic equipment clip 32, and secondary treatment device r2 is mounted on On second level therapeutic equipment clip 33, s2 is clamped by the second pinching valve 20 at the 5th pinching, and t2 is by the first pinching valve at the 6th pinching 19 clamp, the 5th air detectors detect position w2 by 13 return line of the 4th Ultrasonic Wave Air Detector whether there is air or The pipeline of person's bubble, heater heating position x2 is put into heater 7, protects the blood plasma of purification or the temperature of blood and human body temperature It holds unanimously, patient is allowed to feel more comfortable.
Equipment running process:
Operational process cooperates attached drawing 1, Fig. 2 and Fig. 4.Mating consumptive material operation machine is first installed, at this time in addition to the second pinching valve 20 is beaten It opens, remaining pinching valve is in closed state, according to prompt, opens the 4th hemostatic clamp, opens the 7th hemostatic clamp, use physiological saline Primary treatment device q2, secondary treatment device r2 are rinsed, or syntagmatic is opened and closed come single by the 5th hemostatic clamp and the 6th hemostatic clamp Primary treatment device and secondary treatment device are solely rinsed, the liquid after flushing enters waste fluid bag, after the completion of flushing, closes the 5th hemostasis Folder closes the 6th hemostatic clamp, closes the 7th hemostatic clamp, opens the 8th hemostatic clamp, will be connected to cuff interface 8 according to machine prompts The cuff at place is tied to progress human blood-pressure monitoring at human blood collection's arm, at this point, the first pinching valve 19 is closed, the second pinching valve 20 It closes, third pinching valve 21 is opened, and the 4th pinching valve 22 is closed, and the 5th pinching valve 25 is closed, and the 6th pinching valve 26 is opened, and the 7th Pinching valve 27 is opened, and centrifuge 5 starts running.Then human vas puncture is carried out, blood of human body enters machine hemostix, opens First hemostatic clamp, while blood pump 9 and anticoagulant pump 15 start according to set proportion operation clockwise, it is complete at Fig. 4 expression Blood starts to open the second hemostatic clamp to external flowing under the action of blood pump 9, and whole blood enters the bag that keeps sample, in case subsequent blood Detection is used, and the second hemostatic clamp is closed after the completion of keeping sample, and blood passes sequentially through as the first Ultrasonic Wave Air Detector position c2, the second surpasses Sound wave air detectors position d2, first filter e2, the 7th pinching valve position g2, the 4th air detectors detection position i2, blood pump Pipe j2, Centrifuge Cup z2, according to iuntercellular difference of specific gravity, centrifugation separates blood plasma and haemocyte, and the blood plasma isolated enters plasma bags, Pipeline detector 24 monitors pipeline inner cell composition in real time, when discovery blood plasma and red blood cell interface reach pipeline detector 24 The second pinching valve 20 is opened when setting, and centrifuge 5 is out of service, and blood pump 9 rotates counterclockwise, and equipment starts to feed back in Centrifuge Cup z2 Haemocyte to human body, haemocyte passes sequentially through blood pump line j2 at this time, and the 4th air detectors detect position i2, the 7th pinching valve Position g2, first filter e2, since first pressure detector connector f2 is connected on first pressure detector 4, real time monitoring The blood pressure of the Huis' body, haemocyte pass sequentially through the second Ultrasonic Wave Air Detector position d2, the first Ultrasonic Wave Air Detector position c2, Machine blood taking needle, Hui Renti.It feeds back blood plasma pump 18 simultaneously to start to work, blood plasma flows through the second filter o2, and second pressure control is surveyed Device connector p2, since second pressure detector connector p2 is connected in blood plasma pressure monitor shown in Fig. 2 36, so real When monitoring blood plasma enter the blood plasma pressure value before primary treatment device q2.Blood plasma passes sequentially through primary treatment device q2, secondary treatment device R2, t2 at the 6th pinching, blood plasma feed back bag, and the 5th air detectors detect position w2, and heater heats position x2, device assembly of transfusing blood, Last the Huis' body.
Three blood of embodiment separates the combination of dental unit complete machine Fig. 1, Fig. 2 and Fig. 5 respectively with regard to the installation of consumptive material and equipment Operational process be illustrated:
The installation of consumptive material:
Setting agent pump pipe a3 is installed in anticoagulant pump 15, and third air detectors detect position b3 by the 5th Ultrasonic Wave Air Detector 14 detections, which check, whether there is air or bubble in anti-coagulants pipeline, the first air detectors detect position c3 by the first ultrasonic wave Air detectors 1, which detect, whether there is air or bubble in pipeline, the second air detectors detect position d3 by the second ultrasonic wave Air detectors 2, which detect, whether there is air or bubble in pipeline, first filter e3 is mounted on first filter clip 3 On, the first pressure detector connector f3 connecting with first filter e3 is mounted on first pressure detector 4, the first pinching Place g3 is clamped by the 7th pinching valve 27, and h3 is clamped by the 6th pinching valve 26 at the second pinching, and the 4th air detectors detect position i3 Being detected by third Ultrasonic Wave Air Detector 6 whether there is air or bubble in pipeline, blood pump line j3 is mounted on blood pump On, separate cup z3 is mounted in centrifuge 5, and pipeline detector detection position k3 is detected by pipeline detector 24, l3 at third pinching Clamped by the 4th pinching valve 22, plasma bags are hung on electronic scale 23, at the 4th pinching m3 clamped by third pinching valve 21, blood plasma pump Pipe n3 is mounted in blood plasma pump 18, and the second filter o3 is mounted on the second filter clip 35, the connection of second pressure detector Head p3 is plugged on second pressure detector 36, and primary treatment device q3 is mounted on first order therapeutic equipment clip 32, secondary treatment Device r3 is mounted on second level therapeutic equipment clip 33, and s3 is clamped by the second pinching valve 20 at the 5th pinching, at the 6th pinching t3 by First pinching valve 19 is clamped, and y3 is clamped by third pinching valve 25 at the 7th pinching,
5th air detectors detect position w3 by 13 return line of the 4th Ultrasonic Wave Air Detector whether there is air or The pipeline of bubble, heater heating position x3 is put into heater 7, keeps the blood plasma of purification or the temperature of blood and human body temperature Unanimously, patient is allowed to feel more comfortable.
Equipment running process:
Operational process cooperates attached drawing 1, Fig. 2 and Fig. 5.Mating consumptive material operation machine is first installed, at this time in addition to the second pinching valve 20 is beaten It opens, remaining pinching valve is in closed state, according to prompt, opens the 4th hemostatic clamp, opens the 7th hemostatic clamp, use physiological saline Primary treatment device q3, secondary treatment device r3 are rinsed, or syntagmatic is opened and closed come single by the 5th hemostatic clamp and the 6th hemostatic clamp Primary treatment device and secondary treatment device are solely rinsed, the liquid after flushing enters waste fluid bag, after the completion of flushing, closes the 5th hemostasis Folder, the 6th hemostatic clamp, the 7th hemostatic clamp open the 8th hemostatic clamp, will be connected to the cuff at cuff interface 8 according to machine prompts It is tied to progress human blood-pressure monitoring at human blood collection's arm, at this point, the first pinching valve 19 is closed, the second pinching valve 20 is closed, the Three pinching valves 21 are opened, and the 4th pinching valve 22 is closed, and the 5th pinching valve 25 is closed, and the 6th pinching valve 26 is opened, the 7th pinching valve 27 open, and centrifuge 5 starts running.Then human vas puncture is carried out, blood of human body enters machine hemostix, opens first and stops Blood folder, while blood pump 9 and anticoagulant pump 15 start according to set proportion operation clockwise, whole blood is in blood at Fig. 4 expression Starting to open the second hemostatic clamp to external flowing under the action of liquid pump 9, whole blood enters the bag that keeps sample, in case subsequent blood detection is used, The second hemostatic clamp is closed after the completion of keeping sample, blood passes sequentially through as the first Ultrasonic Wave Air Detector position c3, the second ultrasonic air Gas detector position d3, first filter e3, the 7th pinching valve position g3, the 4th air detectors detection position i3, blood pump line j3, from Heart cup z3, according to iuntercellular difference of specific gravity, centrifugation separates blood plasma and haemocyte, and the blood plasma isolated enters plasma bags, and pipeline is visited Device 24 is surveyed, monitors pipeline inner cell composition in real time, when finding that blood plasma and red blood cell interface reach pipeline 24 position of detector the Two pinching valves 20 are opened, and centrifuge 5 is out of service, and blood pump 9 rotates counterclockwise, and equipment starts to feed back, at this time the 7th pinching valve 27 close, and the 6th pinching valve 26 is closed, and the second pinching valve 20 is closed, the 2nd the 5th pinching valve 25, and third pinching valve is opened, and 21, First pinching valve 19 is opened, and the haemocyte in Centrifuge Cup z3 enters blood plasma along pipeline and feeds back bag.Blood plasma pump 18 simultaneously is fed back to open Beginning work, blood plasma flow through the second filter o3, and second pressure detector connector p3 is connected to the monitoring of blood plasma pressure shown in Fig. 2 On device 36, real time monitoring blood plasma enters the blood plasma pressure value before primary treatment device q3.Blood plasma passes sequentially through primary treatment device q3, and two Grade therapeutic equipment r3, t3 at the 6th pinching, blood plasma feed back bag, detect position through the 5th air detectors with the mixed blood of haemocyte W3, heater heat position x3, device assembly of transfusing blood, last the Huis' body.
Example IV blood separates the combination of dental unit complete machine Fig. 1, Fig. 2 and Fig. 6 respectively with regard to the installation of consumptive material and equipment Operational process be illustrated:
The installation of consumptive material:
Setting agent pump pipe a4 is installed in anticoagulant pump 15, and third air detectors detect position b4 by the 5th Ultrasonic Wave Air Detector 14 detections, which check, whether there is air or bubble in anti-coagulants pipeline, the first air detectors detect position c4 by the first ultrasonic wave Air detectors 1, which detect, whether there is air or bubble in pipeline, the second air detectors detect position d4 by the second ultrasonic wave Air detectors 2, which detect, whether there is air or bubble in pipeline, first filter e4 is mounted on first filter clip 3 On, the first pressure detector connector f4 connecting with first filter e4 is mounted on first pressure detector 4, the first pinching Place g4 is clamped by the 7th pinching valve 27, and h4 is clamped by the 6th pinching valve 26 at the second pinching, and the 4th air detectors detect position i4 Being detected by third Ultrasonic Wave Air Detector 6 whether there is air or bubble in pipeline, blood pump line j4 is mounted on blood pump On, separate cup z4 is mounted in centrifuge 5, and pipeline detector detection position k4 is detected by pipeline detector 24, l4 at third pinching Clamped by the 4th pinching valve 22, plasma bags are hung on electronic scale 23, at the 4th pinching m4 clamped by third pinching valve 21, blood plasma pump Pipe n4 is mounted in blood plasma pump 18, and the second filter o4 is mounted on the second filter clip 35, the connection of second pressure detector Head p4 is plugged on second pressure detector 36, and primary treatment device q4 is mounted on first order therapeutic equipment clip 32, secondary treatment Device r4 is mounted on second level therapeutic equipment clip 33, and s4 is clamped by the second pinching valve 20 at the 5th pinching, at the 6th pinching t4 by First pinching valve 19 is clamped, and y4 is clamped by third pinching valve 25 at the 7th pinching,
Third pressure detector connector v4 is plugged on third pressure detector 12, and third filter u4 is mounted on third filtering On device clip 11, the 5th air detectors detect position w4 by whether there is sky in 13 return line of the 4th Ultrasonic Wave Air Detector The pipeline of gas or bubble, heater heating position x4 is put into heater 7, makes the blood plasma of purification or the temperature and human temperature of blood Degree is consistent, and patient is allowed to feel more comfortable.
The operational process of equipment:
Equipment running process cooperates attached drawing 1, Fig. 2, Fig. 6.Mating consumptive material operation machine is first installed, at this time in addition to the second pinching valve 20 It opens, remaining pinching valve is in closed state, according to prompt, opens the 4th hemostatic clamp, opens the 7th hemostatic clamp, use physiology salt Water rinses primary treatment device q4, secondary treatment device r4, or the opening and closing syntagmatic by the 5th hemostatic clamp and the 6th hemostatic clamp Primary treatment device and secondary treatment device individually are rinsed, the liquid after flushing enters waste fluid bag, after the completion of flushing, closes the 5th and stops Blood folder, third hemostatic clamp, the 4th hemostatic clamp, the 6th hemostatic clamp, the 7th hemostatic clamp, will be connected to cuff interface according to machine prompts Cuff at 8 is tied to progress human blood-pressure monitoring at human blood collection's arm, at this point, the first pinching valve 19 is closed, the second pinching valve 20 close, and third pinching valve 21 is opened, and the 4th pinching valve 22 is closed, and the 5th pinching valve 25 is closed, and the 6th pinching valve 26 is opened, the Seven pinching valves 27 are opened, and centrifuge 5 starts running.Then human vas puncture is carried out, blood of human body enters machine hemostix, beats The first hemostatic clamp is opened, while blood pump 9 and anticoagulant pump 15 start according to set proportion operation clockwise, at Fig. 4 expression Whole blood starts to open the second hemostatic clamp to external flowing under the action of blood pump 9, and whole blood enters the bag that keeps sample, in case subsequent blood Liquid detection is used, and the second hemostatic clamp is closed after the completion of keeping sample, and blood passes sequentially through as the first Ultrasonic Wave Air Detector position c4, and second Ultrasonic Wave Air Detector position d4, first filter e4, the 7th pinching valve position g4, the 4th air detectors detection position i4, blood Pump line j4, Centrifuge Cup z4, according to iuntercellular difference of specific gravity, centrifugation separates blood plasma and haemocyte, and the blood plasma isolated enters blood plasma Bag, pipeline detector 24 monitor pipeline inner cell composition in real time, when discovery blood plasma and red blood cell interface reach pipeline detector 24 The second pinching valve 20 is opened when position, and centrifuge 5 is out of service, and blood pump 9 rotates counterclockwise, and equipment starts to feed back, and at this time the Seven pinching valves 27 are closed, and the 6th pinching valve 26 is closed, and the second pinching valve 20 is closed, and the 5th pinching valve 25 is opened, third pinching valve 21 open, and the first pinching valve 19 is opened, and the haemocyte in Centrifuge Cup z4 enters the feedback pipe through y4 at the 7th pinching along pipeline Road.It feeds back blood plasma pump 18 simultaneously to start to work clockwise, blood plasma flows through the second filter o4, second pressure detector connector p4 It is connected in blood plasma pressure monitor shown in Fig. 2 36, real time monitoring blood plasma enters the blood plasma pressure value before primary treatment device q4.Blood Slurry passes sequentially through primary treatment device q4, secondary treatment device r4, t4 at the 6th pinching, with the mixed blood of haemocyte through the 5th sky Gas detector detects position w4, and heated device heats position x4, device assembly of transfusing blood, last the Huis' body.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with A variety of variations, modification, replacement can be carried out to these embodiments without departing from the principles and spirit of the present invention by understanding And modification, the scope of the present invention is defined by the appended.

Claims (10)

1. a kind of blood separates dental unit complete machine, including rack, which is characterized in that be equipped with anti-coagulants in the rack If pump, blood pump, blood plasma pump, anti-coagulants hanger, physiological saline hanger, centrifuge, pipeline detector, therapeutic equipment clip, dry-pressing Force detector, several Ultrasonic Wave Air Detectors and several pinching valves;The centrifuge is located at frame central position, by centrifuge It is provided with the blood pump and pipeline detector;The anti-coagulants hanger and physiological saline hanger are mounted on the two sides of rack.
2. blood according to claim 1 separates dental unit complete machine, which is characterized in that the pressure detector includes First pressure detector, second pressure detector, third pressure detector.
3. blood according to claim 1 separates dental unit complete machine, which is characterized in that the ultrasonic wave air detection Device includes the first, second to the 5th Ultrasonic Wave Air Detector.
4. blood according to claim 1 separates dental unit complete machine, which is characterized in that the pinching valve includes the One, the second to the 7th pinching valve.
5. blood according to claim 1 separates dental unit complete machine, it is characterised in that the therapeutic equipment clip is at least Including first order therapeutic equipment clip and second level therapeutic equipment clip.
6. blood according to any one of claims 1 to 5 separates dental unit complete machine, which is characterized in that under the rack Side is equipped with the universal wheel mobile convenient for complete machine.
7. blood according to any one of claims 1 to 5 separates dental unit complete machine, which is characterized in that in the rack The heater for keeping blood plasma return line or blood backflow pipeline constant temperature is installed.
8. blood according to any one of claims 1 to 5 separates dental unit complete machine, which is characterized in that in the rack Sleeve bag connector for bag of tucking inside the sleeve is installed.
9. blood according to any one of claims 1 to 5 separates dental unit complete machine, which is characterized in that in the rack It is also equipped with the electronic scale for weighing blood plasma.
10. blood according to any one of claims 1 to 5 separates dental unit complete machine, which is characterized in that in the rack It is also equipped with heat-sealing device.
CN201811489848.XA 2018-12-06 2018-12-06 A kind of blood separation dental unit complete machine Pending CN109568700A (en)

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CN110680974A (en) * 2019-10-24 2020-01-14 成都市佳颖医用制品有限公司 Monitoring system and monitoring method for blood replacement device
CN110833628A (en) * 2019-11-25 2020-02-25 四川南格尔生物科技有限公司 Online ultraviolet inactivation process
CN110833626A (en) * 2019-11-25 2020-02-25 四川南格尔生物科技有限公司 Ultraviolet inactivation pipeline system
CN113041420A (en) * 2021-04-30 2021-06-29 西安交通大学医学院第一附属医院 Blood component automatic balance separator
WO2023019610A1 (en) * 2021-08-16 2023-02-23 赛若麦得(上海)生物技术有限公司 Low volume plasma exchange device

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CN108310503A (en) * 2018-02-08 2018-07-24 中南大学湘雅二医院 A kind of Almightiness type plasma purification system based on centrifugal separation plasma method
CN209864814U (en) * 2018-12-06 2019-12-31 成都创合丰生物科技有限公司 Blood separation comprehensive treatment machine complete machine

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CN106913918A (en) * 2017-03-29 2017-07-04 艾沃生物科技(苏州)有限公司 A kind of external circulating therapy centrifugal plasma isolation of purified instrument
CN108310503A (en) * 2018-02-08 2018-07-24 中南大学湘雅二医院 A kind of Almightiness type plasma purification system based on centrifugal separation plasma method
CN209864814U (en) * 2018-12-06 2019-12-31 成都创合丰生物科技有限公司 Blood separation comprehensive treatment machine complete machine

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110680974A (en) * 2019-10-24 2020-01-14 成都市佳颖医用制品有限公司 Monitoring system and monitoring method for blood replacement device
CN110833628A (en) * 2019-11-25 2020-02-25 四川南格尔生物科技有限公司 Online ultraviolet inactivation process
CN110833626A (en) * 2019-11-25 2020-02-25 四川南格尔生物科技有限公司 Ultraviolet inactivation pipeline system
CN110833628B (en) * 2019-11-25 2021-09-03 四川南格尔生物科技有限公司 Online ultraviolet inactivation process
CN113041420A (en) * 2021-04-30 2021-06-29 西安交通大学医学院第一附属医院 Blood component automatic balance separator
WO2023019610A1 (en) * 2021-08-16 2023-02-23 赛若麦得(上海)生物技术有限公司 Low volume plasma exchange device

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