CN106913918A - A kind of external circulating therapy centrifugal plasma isolation of purified instrument - Google Patents

A kind of external circulating therapy centrifugal plasma isolation of purified instrument Download PDF

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Publication number
CN106913918A
CN106913918A CN201710196185.1A CN201710196185A CN106913918A CN 106913918 A CN106913918 A CN 106913918A CN 201710196185 A CN201710196185 A CN 201710196185A CN 106913918 A CN106913918 A CN 106913918A
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CN
China
Prior art keywords
magnetic valve
peristaltic pump
external circulating
purified
air detectors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710196185.1A
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Chinese (zh)
Inventor
孟茜
王新国
操玮
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Avoix Biotechnology (suzhou) Co Ltd
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Avoix Biotechnology (suzhou) Co Ltd
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Publication date
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Priority to CN201710196185.1A priority Critical patent/CN106913918A/en
Publication of CN106913918A publication Critical patent/CN106913918A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/38Removing constituents from donor blood and storing or returning remainder to body, e.g. for transfusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3626Gas bubble detectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3693Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits using separation based on different densities of components, e.g. centrifuging

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)

Abstract

Present invention is disclosed a kind of external circulating therapy centrifugal plasma isolation of purified instrument, including body, centrifuge, air warning device, pipeline on-off control device, pressure monitoring device, volume control device and red slurry detector, the body includes the vertical panel on front side of middle part, sloping desk on the horizontal panel vertical with vertical panel and horizontal panel, the air warning device, pipeline on-off control device, pressure monitoring device and volume control device are provided with multiple, the horizontal panel is provided centrally with centrifuge, four volume control devices are provided with the sloping desk, the sloping desk top is provided with display screen.The present invention realizes that the extraction of patient's body blood carries out blood plasma separation, and haemocyte is fed back into patient's body, and then blood plasma is purified, and the blood plasma after purification finally is fed back into patient's body;Equipment may move, and improve instrument service efficiency;Display screen is used so that man-machine interaction is good.

Description

A kind of external circulating therapy centrifugal plasma isolation of purified instrument
Technical field
The present invention relates to medical blood sampling apparatus, more particularly to field of blood purification a kind of external circulating therapy with centrifugal Blood plasma isolation of purified instrument.
Background technology
At present, secondary plasma treatment technology has been obtained extensively understanding the fields such as the treatment of associated morbidity material, Severe acute disease General application.Its general principle is that the blood of patient is rotated into the centrifugal force separate for producing into blood through the high speed of centrifuge in vitro Slurry and blood cell composition(Comprising red blood cell, leucocyte and blood platelet etc.).Then blood cell composition is fed back in patient's body, will The blood plasma of separation is transported to filter and is processed, and the blood plasma after treatment finally is fed back into the internal of patient.
The content of the invention
It is an object of the invention to provide a kind of first that blood plasma separation and plasma purification is integrated, patient's body blood is realized Extraction carries out blood plasma separation, and haemocyte is fed back into patient's body, and then blood plasma is purified, and finally returns the blood plasma after purification It is defeated to patient's body;Equipment may move, and improve instrument service efficiency;Display screen is used so that good external of man-machine interaction follows Ring treatment centrifugal plasma isolation of purified instrument.
The technical scheme is that, a kind of external circulating therapy centrifugal plasma isolation of purified instrument, including body, from Scheming, air warning device, pipeline on-off control device, pressure monitoring device, volume control device and red slurry detector, institute State to be fixedly connected below four angles of organism bottom and be provided with roller, the body is including the vertical panel on front side of middle part and vertically Sloping desk on the vertical horizontal panel of panel and horizontal panel, the air warning device, pipeline on-off control device, Pressure monitoring device and volume control device are provided with multiple and are respectively arranged on body, and the horizontal panel center sets Centrifuge is equipped with, first peristaltic pump, top of four volume control devices including lower left are provided with the sloping desk Second peristaltic pump in left side, the 3rd peristaltic pump of upper right and the 4th peristaltic pump of lower right, the sloping desk top Portion is provided with display screen.
In a preferred embodiment of the present invention, the air warning device includes the first air detectors, the second air Detector, the 3rd air detectors, the 4th air detectors, the 5th air detectors and the 6th air detectors.
In a preferred embodiment of the present invention, the pipeline on-off control device includes the firstth magnetic valve, the second electricity Magnet valve, the 3rd magnetic valve, the magnetic valve of the 4th magnetic valve the 5th and the 6th magnetic valve.
In a preferred embodiment of the present invention, the pressure monitoring device includes a DPM and the 2nd DPM.
In a preferred embodiment of the present invention, the vertical panel side is provided with the first air detection of upper and lower parallel connection Device and the second air detectors.
In a preferred embodiment of the present invention, Centrifuge Cup, centrifuge left side correspondence are provided with the centrifuge The first magnetic valve and the 3rd air detectors are provided with, the centrifuge right side is correspondingly arranged on the 4th air detectors, red slurry Detector, the second magnetic valve and the 3rd magnetic valve.
In a preferred embodiment of the present invention, the first peristaltic pump left side is correspondingly arranged on a DPM, described second Peristaltic pump left side is correspondingly arranged on the 5th air detectors, and the 3rd peristaltic pump right side is correspondingly arranged on the 4th magnetic valve and the Five magnetic valves, the 6th air detectors and the 6th magnetic valve are correspondingly arranged between the 3rd peristaltic pump and the 4th peristaltic pump, The 4th peristaltic pump right side is correspondingly arranged on the 2nd DPM.
In a preferred embodiment of the present invention, the display screen is fixedly installed on sloping desk top by display/panel bracket Portion front side.
In a preferred embodiment of the present invention, the body top has been centrally located saline support.
In a preferred embodiment of the present invention, the angle between the sloping desk and horizontal panel is 75 °.
Of the present invention is a kind of external circulating therapy centrifugal plasma isolation of purified instrument, and the present invention is first by blood plasma point From integrated with plasma purification, realize that the extraction of patient's body blood carries out blood plasma separation, haemocyte is fed back into patient's body, so it is right Blood plasma is purified, and the blood plasma after purification finally is fed back into patient's body;Equipment may move, and improve instrument service efficiency;It is aobvious Display screen is used so that man-machine interaction is good.
Brief description of the drawings
Fig. 1 is the structural representation in external circulating therapy centrifugal plasma isolation of purified instrument one of the present invention preferred embodiment Figure.
Specific embodiment
Presently preferred embodiments of the present invention is described in detail below so that advantages and features of the invention can be easier to by It will be appreciated by those skilled in the art that apparent clearly being defined so as to be made to protection scope of the present invention.
Of the present invention is a kind of external circulating therapy centrifugal plasma isolation of purified instrument, as shown in figure 1, including body 1st, centrifuge 2, air warning device, pipeline on-off control device, pressure monitoring device, volume control device and red slurry detection Device 3,1 bottom of the body, four angles lower section is fixedly connected and is provided with roller 4, and the body 1 includes the vertical plane on front side of middle part Sloping desk 7 on the horizontal panel 6 vertical with vertical panel 5 of plate 5 and horizontal panel 6, the air warning device, pipe Road on-off control device, pressure monitoring device and volume control device are provided with multiple and are respectively arranged on body 1, institute State horizontal panel 6 and be provided centrally with centrifuge 2, four volume control devices are provided with the sloping desk 7 left including lower section 3rd peristaltic pump 10 of the second peristaltic pump 9, upper right of the first peristaltic pump 8, upper left of side and the of lower right Four peristaltic pumps 11, the top of the sloping desk 7 is provided with display screen 12.
The air warning device includes the first air detectors 13, the second air detectors 14, the 3rd air detectors 15th, the 4th air detectors 16, the 5th air detectors 17 and the 6th air detectors 18, wherein the first air detectors 13 Setting is failed to report for anti-with the second air detectors 14, as long as the two one is detected air and so alarmed, into alarm treatment Program.
The pipeline on-off control device includes the first magnetic valve 19, the second magnetic valve 20, the electricity of the 3rd magnetic valve the 21, the 4th Magnet valve 22, the 5th magnetic valve 23 and the 6th magnetic valve 24.
The pressure monitoring device includes a DPM25 and the 2nd DPM26, when DPM25 controls blood sampling and feedback Pipeline pressure, mistake mould during the 2nd DPM26 monitoring filterings.
The side of the vertical panel 5 is provided with first air detectors 13 and the second air detectors 14 of upper and lower parallel connection.
Centrifuge Cup 27 is provided with the centrifuge 2, it is empty that the left side of the centrifuge 2 is correspondingly arranged on the first magnetic valve 19 and the 3rd Gas detector 15, the right side of the centrifuge 2 is correspondingly arranged on the 4th air detectors 16, red slurry detector 3, the second magnetic valve 20 And the 3rd magnetic valve 21.
The left side of first peristaltic pump 8 is correspondingly arranged on a DPM25.
The left side of second peristaltic pump 9 is correspondingly arranged on the 5th air detectors 17.
The right side of 3rd peristaltic pump 10 is correspondingly arranged on the 4th magnetic valve 22 and the 5th magnetic valve 23, and the described 3rd wriggles The 6th air detectors 18 and the 6th magnetic valve 24 are correspondingly arranged between the peristaltic pump 11 of pump 10 and the 4th.
The right side of 4th peristaltic pump 11 is correspondingly arranged on the 2nd DPM26.
The display screen 12 is fixedly installed on the top of sloping desk 7 front side by display/panel bracket 28.
The top of the body 1 has been centrally located saline support 29.
Angle between the sloping desk 7 and horizontal panel 6 is 75 °.
First peristaltic pump 8 is blood pump, can be rotated with forward and reverse, reaches blood sampling and the purpose for feeding back;Described Two peristaltic pumps 9 are anticoagulant pump, according to the ratio of set whole blood and anti-coagulants, voluntarily set rotating speed;Described 3rd wriggles Pump 10 is slurry recirculating pump, and the 4th peristaltic pump 11 is filter pulp pump, the 3rd peristaltic pump 10 and the common promotion blood plasma of the 4th peristaltic pump 11 Plasmapheresis is carried out through filter, and adjusts filter internal pressure.
3rd peristaltic pump 10 and the common regulation filter internal pressure of the 4th peristaltic pump 11, it is also possible to by only setting the Four peristaltic pumps 11, and cancel the 3rd peristaltic pump 10, plasmapheresis is reached by individually the 4th peristaltic pump 11 of control and control is pressed The purpose of power.
The display screen 12 be touch screens, make operating personnel dress rubber gloves under conditions of, can still operate from Core type blood plasma isolation of purified instrument, the setting in centrifugal plasma isolation of purified instrument operating process is grasped by display screen 12 Make, lift man-machine interaction.
The red slurry detector 3 detects red blood cell by the change of voltage, according to PC between Different Individual not Together, the voltage on the basis of initial plasma voltage, with the real-time voltage in reference voltage and monitoring process as parameter, sets alarm limit Value.
The saline support 29 can also hang other storage bags in addition to salt solution is hung.
The roller 4 has locking and loosens two states, and seperator is maintained static during locking, and seperator possesses shifting when loosening Kinetic force.
In addition, A is patient in accompanying drawing, B is anti-coagulants, and C is physiological saline, and D is slurry storing bag, and E is filter, and F is waste fluid bag, G is overfall bag, and H is plasma bags.
Operation principle:
If Fig. 2 is the schematic diagram in centrifugal plasma isolation of purified instrument one of the present invention preferred embodiment, the first peristaltic pump 8 is extracted suffers from Person's A whole bloods, the second peristaltic pump 9 extracts anti-coagulants B, and the 5th air detectors 17 ensures do not exist bubble in the anti-coagulants B for extracting, Whether there is bubble in the whole blood containing anti-coagulants B that first air detectors 13 and the monitoring of the second air detectors 14 are extracted, the One DPM25 monitors pipeline inner pressure, and the whole blood containing anti-coagulants B is by the first magnetic valve 19, the 3rd air detectors 15 and first Peristaltic pump 8 into centrifuge 2 Centrifuge Cup 27 in carry out blood plasma separation, after the completion of separation haemocyte original road feed back to human body, blood Slurry enters slurry storing bag D by 3 and second magnetic valve of red slurry detector 20, and the 4th peristaltic pump 11 extracts the blood plasma in plasma bags H, the Four peristaltic pumps 11 and the common promotion blood plasma of the 3rd peristaltic pump 10 enter overfall bag G through filter E by the 4th magnetic valve 22, And then feed back patient A.
Repeatedly circulation said process is until blood plasma isolation of purified amount demand needed for completing.
Of the present invention is a kind of external circulating therapy centrifugal plasma isolation of purified instrument, and the present invention is first by blood plasma point From integrated with plasma purification, realize that the extraction of patient's body blood carries out blood plasma separation, haemocyte is fed back into patient's body, so it is right Blood plasma is purified, and the blood plasma after purification finally is fed back into patient's body;Equipment may move, and improve instrument service efficiency;It is aobvious Display screen is used so that man-machine interaction is good.
Specific embodiment of the invention is the foregoing is only, but protection scope of the present invention is not limited thereto, it is any Those of ordinary skill in the art disclosed herein technical scope in, the change that can expect without creative work or Replace, should all be included within the scope of the present invention.Therefore, protection scope of the present invention should be limited with claims Fixed protection domain is defined.

Claims (10)

1. a kind of external circulating therapy centrifugal plasma isolation of purified instrument, including body, centrifuge, air warning device, pipe Road on-off control device, pressure monitoring device, volume control device and red slurry detector, it is characterised in that:The body bottom Four angles in portion lower section is fixedly connected and is provided with roller, and the body includes that the vertical panel on front side of middle part is vertical with vertical panel Horizontal panel and horizontal panel on sloping desk, the air warning device, pipeline on-off control device, pressure monitoring Device and volume control device are provided with multiple and are respectively arranged on body, and the horizontal panel is provided centrally with centrifugation Machine, is provided with the first peristaltic pump of four volume control devices including lower left, the of upper left on the sloping desk 3rd peristaltic pump and the 4th peristaltic pump of lower right of two peristaltic pumps, upper right, the sloping desk top are provided with Display screen.
2. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:The sky Gas warning device includes the first air detectors, the second air detectors, the 3rd air detectors, the 4th air detectors, the Five air detectorses and the 6th air detectors.
3. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:The pipe Road on-off control device include the firstth magnetic valve, the second magnetic valve, the 3rd magnetic valve, the magnetic valve of the 4th magnetic valve the 5th and 6th magnetic valve.
4. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:The pressure Power monitoring device includes a DPM and the 2nd DPM.
5. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:It is described perpendicular Face the first air detectors and the second air detectors that plate side is provided with upper and lower parallel connection directly.
6. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:It is described from Be provided with Centrifuge Cup in scheming, the centrifuge left side is correspondingly arranged on the first magnetic valve and the 3rd air detectors, it is described from Scheming right side is correspondingly arranged on the 4th air detectors, red slurry detector, the second magnetic valve and the 3rd magnetic valve.
7. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:Described One peristaltic pump left side is correspondingly arranged on a DPM, and the second peristaltic pump left side is correspondingly arranged on the 5th air detectors, described 3rd peristaltic pump right side is correspondingly arranged on the 4th magnetic valve and the 5th magnetic valve, between the 3rd peristaltic pump and the 4th peristaltic pump The 6th air detectors and the 6th magnetic valve are correspondingly arranged on, the 4th peristaltic pump right side is correspondingly arranged on the 2nd DPM.
8. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:It is described aobvious Display screen is fixedly installed on sloping desk top front side by display/panel bracket.
9. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:The machine Body top has been centrally located saline support.
10. external circulating therapy according to claim 1 centrifugal plasma isolation of purified instrument, it is characterised in that:It is described Angle between sloping desk and horizontal panel is 75 °.
CN201710196185.1A 2017-03-29 2017-03-29 A kind of external circulating therapy centrifugal plasma isolation of purified instrument Pending CN106913918A (en)

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CN201710196185.1A CN106913918A (en) 2017-03-29 2017-03-29 A kind of external circulating therapy centrifugal plasma isolation of purified instrument

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Application Number Priority Date Filing Date Title
CN201710196185.1A CN106913918A (en) 2017-03-29 2017-03-29 A kind of external circulating therapy centrifugal plasma isolation of purified instrument

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109568700A (en) * 2018-12-06 2019-04-05 成都创合丰生物科技有限公司 A kind of blood separation dental unit complete machine
CN113350598A (en) * 2021-04-07 2021-09-07 刘成一 Extracorporeal circulation treatment apparatus
WO2023019610A1 (en) * 2021-08-16 2023-02-23 赛若麦得(上海)生物技术有限公司 Low volume plasma exchange device
WO2023024166A1 (en) * 2021-08-25 2023-03-02 赛若麦得(上海)生物技术有限公司 Plasma collector

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201008668Y (en) * 2006-08-24 2008-01-23 史禾祥 Multifunctional blood purifying therapeutical instrument
CN104491945A (en) * 2014-12-31 2015-04-08 成都市佳颖医用制品有限公司 Blood plasma collecting device
CN204352269U (en) * 2014-12-31 2015-05-27 成都市佳颖医用制品有限公司 A kind of sampled plasma device
CN104667362A (en) * 2015-03-24 2015-06-03 傅敏 Full-automatic whole blood collection separator and matched disposable collecting-separating device
CN204521743U (en) * 2015-04-01 2015-08-05 江西生物制品研究所 A kind of blood component separator
CN207575495U (en) * 2017-03-29 2018-07-06 艾沃生物科技(苏州)有限公司 A kind of external circulating therapy centrifugal plasma isolation of purified instrument

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN201008668Y (en) * 2006-08-24 2008-01-23 史禾祥 Multifunctional blood purifying therapeutical instrument
CN104491945A (en) * 2014-12-31 2015-04-08 成都市佳颖医用制品有限公司 Blood plasma collecting device
CN204352269U (en) * 2014-12-31 2015-05-27 成都市佳颖医用制品有限公司 A kind of sampled plasma device
CN104667362A (en) * 2015-03-24 2015-06-03 傅敏 Full-automatic whole blood collection separator and matched disposable collecting-separating device
CN204521743U (en) * 2015-04-01 2015-08-05 江西生物制品研究所 A kind of blood component separator
CN207575495U (en) * 2017-03-29 2018-07-06 艾沃生物科技(苏州)有限公司 A kind of external circulating therapy centrifugal plasma isolation of purified instrument

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109568700A (en) * 2018-12-06 2019-04-05 成都创合丰生物科技有限公司 A kind of blood separation dental unit complete machine
CN113350598A (en) * 2021-04-07 2021-09-07 刘成一 Extracorporeal circulation treatment apparatus
WO2023019610A1 (en) * 2021-08-16 2023-02-23 赛若麦得(上海)生物技术有限公司 Low volume plasma exchange device
WO2023024166A1 (en) * 2021-08-25 2023-03-02 赛若麦得(上海)生物技术有限公司 Plasma collector

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