CN217796723U

CN217796723U - Disposable blood separation device

Info

Publication number: CN217796723U
Application number: CN202221997079.6U
Authority: CN
Inventors: 王鹏
Original assignee: Sichuan Tianfu Hunter Life Technology Co ltd
Current assignee: Sichuan Tianfu Hunter Life Technology Co ltd
Priority date: 2022-07-28
Filing date: 2022-07-28
Publication date: 2022-11-15
Anticipated expiration: 2032-07-28

Abstract

The utility model discloses a disposable blood separator, including separation bag and rotary drum, form the conical separating tank in the rotary drum, the separation bag is established in the separating tank, is equipped with one-level separation chamber and second grade separation chamber in the separation bag, and the whole blood inlet tube extends the one-level separation intracavity, and the plasma outlet pipe extends the top in one-level separation chamber, and the blood cell outlet pipe extends the bottom in one-level separation chamber, and the PRP outlet pipe extends the bottom in second grade separation chamber, and poor platelet plasma outlet pipe extends the top in second grade separation chamber, and the plasma inlet tube extends the second grade separation intracavity. The utility model has the advantages that: the separation bag is utilized to realize two-stage separation, and the separation bag has the advantage of good separation effect while having high separation efficiency; and (3) monitoring the concentration of the platelets in real time, and adding poor platelet plasma into the platelet-rich plasma to obtain a platelet-rich concentrated solution or a platelet-rich suspension with controllable concentration.

Description

Disposable blood separator

Technical Field

The utility model relates to a blood separation technical field specifically is a disposable blood separator.

Background

In the process of collecting platelets by adopting Amicus equipment and consumables, after blood components are separated, the platelets are retained in a separation cavity due to centrifugal force and form a block shape, part of the platelets are adhered to the separation cavity, and plasma with a proper volume needs to be manually pumped into the separation cavity and manually shaken. When the platelet clumps are mixed, a high concentration platelet plasma is formed, which is then transferred to a platelet collection bag by gravity or squeeze separation.

However, the degree of platelet adhesion is different, and the shaking force and angle of operators with different experiences are different, so that the platelet clumps cannot be mixed uniformly and even cannot be mixed uniformly, and meanwhile, the platelet can not be collected sufficiently by gravity or extrusion transfer, which causes the waste of the platelet. Meanwhile, the manual shaking also occupies the time of operators, and the workload is increased.

SUMMERY OF THE UTILITY MODEL

The utility model aims to provide a: provides a disposable blood separating device, which solves the problem that the platelet-rich concentrated solution with controllable concentration can not be collected on line in the blood separating process.

The purpose of the utility model is realized through the following technical scheme:

a disposable blood separating device comprises a separating bag and a rotary drum, wherein a conical separating groove is formed in the rotary drum, the separating bag is arranged in the separating groove, a primary separating cavity and a secondary separating cavity are arranged in the separating bag, a whole blood inlet pipe extends into the primary separating cavity, a plasma outlet pipe extends to the top of the primary separating cavity, a blood cell outlet pipe extends to the bottom of the primary separating cavity, a PRP outlet pipe extends to the bottom of the secondary separating cavity, a poor platelet plasma outlet pipe extends to the top of the secondary separating cavity, and a plasma inlet pipe extends into the secondary separating cavity.

Furthermore, the separation bag is of a fan-shaped structure.

Furthermore, the primary separation cavity and the secondary separation cavity are respectively positioned at two sides of the separation bag.

Further, the separation grooves are formed in the rotary drum along the circumferential direction and are annular.

Further, the rotary drum include round platform, rotary drum lower round platform, rotary drum inner wall and rotary drum outer wall on the rotary drum, round platform is connected with the upper end of rotary drum inner wall, rotary drum outer wall respectively on the rotary drum, rotary drum inner wall and rotary drum outer wall are round platform form cross-section, round platform is connected with the lower extreme of rotary drum inner wall, rotary drum outer wall respectively under the rotary drum, forms the separating tank before round platform, rotary drum lower round platform, rotary drum inner wall and the rotary drum outer wall on the rotary drum.

Furthermore, the separation bag and the rotary drum are respectively provided with a corresponding fixing hole, and the separation bag is fixed on the rotary drum through a fixing buckle and the fixing hole.

Furthermore, the bottom of the rotary drum is provided with a support opening, and the top of the rotary drum is provided with a support mounting part.

Furthermore, the whole blood inlet pipe extends to the middle part of the primary separation cavity, and the plasma inlet pipe extends to the middle part of the secondary separation cavity.

Further, the PRP outlet tube and the poor platelet plasma inlet tube jointly extend to the bottom port of the secondary separation chamber.

Furthermore, the platelet concentration monitor is arranged opposite to the bottom port, and the platelet concentration monitor is linked with the valve at the outlet end of the poor platelet plasma inlet pipe through a controller.

The utility model has the advantages that: the separation bag is utilized to realize two-stage separation, and the separation bag has the advantage of good separation effect while having high separation efficiency; the concentration of the platelet is monitored in real time, and poor platelet plasma is added into the platelet-rich plasma to obtain a concentration-controllable platelet-rich concentrated solution or a platelet-rich suspension.

The main scheme and the further selection schemes of the utility model can be freely combined to form a plurality of schemes, which are the schemes that can be adopted and claimed by the utility model; in addition, the utility model can be freely combined between the (non-conflict selection) selections and other selections. The skilled person will understand that there are many combinations, which are the technical solutions to be protected by the present invention, and the embodiments are not exhaustive, according to the prior art and the common general knowledge.

Drawings

Fig. 1 is a schematic structural diagram of the present invention.

Fig. 2 is a schematic structural view of the separation bag of the present invention.

Fig. 3 is a schematic structural view of the drum of the present invention.

In the figure: 1-first-stage separation cavity, 2-second-stage separation cavity, 3-upper round table of rotary drum, 4-lower round table of rotary drum, 5-fixing hole, 6-inner wall of rotary drum, 7-outer wall of rotary drum, 8-rotating bracket, 9-platelet-rich plasma and 10-poor platelet plasma; 11-whole blood inlet tube, 12-plasma outlet tube, 13-blood cell outlet tube, 21-PRP outlet tube, 22-poor platelet plasma outlet tube, 23-plasma inlet tube, 24-poor platelet plasma inlet tube, 25-bottom port; 100-separation bag, 200-drum.

Detailed Description

The present invention will be further described with reference to the following specific embodiments and the accompanying drawings.

Referring to fig. 1-3, a disposable blood separation device includes a separation bag 100 and a bowl 200. The separation bag 100 is fixedly installed in the separation groove formed in the rotary drum 200, and then the separation bag 100 is driven by the rotary drum 200 to synchronously rotate so as to separate the blood in the separation bag 100.

The separation bag 100 is in a fan-shaped structure, so that the separation bag 100 is matched with the separation groove on the rotary drum 200 in shape. A primary separation cavity 1 and a secondary separation cavity 2 are arranged in the separation bag 100, and the primary separation cavity 1 and the secondary separation cavity 2 are respectively positioned on two sides of the separation bag 100.

The whole blood inlet tube 11 extends to the middle of the primary separation chamber 1 so as to input whole blood into the primary separation chamber 1. The plasma outlet tube 12 extends to the top of the primary separation chamber 1 to withdraw the separated plasma from the top. The blood cell outlet tube 13 extends to the bottom of the primary separation chamber 1 to draw the separated blood cells from the bottom.

The PRP outlet tube 21 extends to the bottom of the secondary separation chamber 2 to withdraw the separated platelet rich plasma 9 (i.e., PRP). The poor platelet plasma outlet tube 22 extends to the top of the secondary separation chamber 2 to draw out the separated poor platelet plasma. The plasma inlet tube 23 extends to the middle of the secondary separation chamber 2 to supply plasma to the secondary separation chamber.

The PRP outlet tube 21 and the poor platelet plasma inlet tube 24 extend to the bottom port 25 of the secondary separation chamber 2, so that the poor platelet plasma can be injected into the bottom port 25 through the poor platelet plasma inlet tube 24, and the poor platelet plasma and the platelet rich plasma at the bottom port 25 are mixed to obtain the platelet rich concentrated solution or the platelet rich suspension solution with the required concentration.

The platelet concentration monitor is opposite to the bottom port 25, the platelet concentration monitor adopts an optical monitor and an interface imaging detector, the obtained monitoring value corresponds to the platelet concentration through a certain algorithm, and the platelet concentration monitor is linked with a valve at the outlet end of the poor platelet plasma inlet pipe 24 through a controller to realize intelligent linkage.

The drum 200 is formed with separation grooves in a circumferential and annular shape, similar to a circular truncated cone-like structure, for loading the fan-shaped separation bags 100. The separation bag 100 and the rotary drum 200 are provided with corresponding fixing holes 5, and the separation bag 100 is inserted into the fixing holes 5 through fixing buttons to be fixed on the rotary drum 200.

Specifically, the rotary drum 200 comprises a rotary drum upper circular table 3, a rotary drum lower circular table 4, a rotary drum inner wall 6 and a rotary drum outer wall 7, the rotary drum upper circular table 3 is connected with the upper ends of the rotary drum inner wall 6 and the rotary drum outer wall 7 respectively, the rotary drum inner wall 6 and the rotary drum outer wall 7 are circular table-shaped cross sections, the rotary drum lower circular table 4 is connected with the lower ends of the rotary drum inner wall 6 and the rotary drum outer wall 7 respectively, and the rotary drum upper circular table 3, the rotary drum lower circular table 4, the rotary drum inner wall 6 and the rotary drum outer wall 7 form a separation groove in front.

In order to insert the separation bag 100 into the drum 200, the drum outer wall 7 can be designed as a block-like structure and can be detachably mounted on the drum 200. The outer wall 7 of the bowl is removed when the separation bag 100 is loaded or unloaded, and the outer wall 7 of the bowl is fixed when centrifugal separation is performed.

Be equipped with the support opening on the rotary drum lower round platform 4 to on loading the rotary drum from top to bottom and rotating support 8, be equipped with the support mounting portion on the rotary drum round platform 3, realize that rotary drum 200 is fixed with being connected of rotating support 8, when centrifugal separation, utilize rotating support 8 to drive rotary drum 200 and rotate, realize the centrifugation.

The utility model discloses a work flow:

the rotating bracket 8 rotates at high speed to drive the separation bag 100 to rotate, and single-stage or multi-stage treatment can be carried out. The primary separation chamber 1 enters the whole blood through the whole blood inlet tube 11, and the primary separation chamber 1 separates the anticoagulated whole blood into blood cells and plasma, one of which components, depending on the application requirements, may be pumped out and transferred to a transfer bag for further processing.

In a multi-stage process, one of the components of the plasma is transferred to the transfer bag, from which the plasma enters the secondary separation chamber 2 through the plasma inlet line 23. In the process, the fractions in the secondary separation chamber 2 are further separated into sub-fractions, wherein the less dense sub-fractions, such as the poor platelet plasma 10, are pumped via the poor platelet plasma outlet tube 22 to the poor platelet plasma storage container. According to the principle of centrifugation, the denser subcomponents such as platelet rich plasma 9 are arranged laterally side by side along the bottom edge of the first stage separation chamber.

Because the secondary separation chamber 2 is a sloped cavity, the denser sub-components such as platelet rich plasma 9 are collected at the bottom port 25 after separation. The concentration of the platelets is monitored by monitoring the bottom port 25, and then the platelet-rich concentrated solution or the platelet-rich suspension solution with controllable concentration is obtained by linking a valve corresponding to the bottom port 25 of the platelet-poor plasma inlet pipe 24.

The aforesaid the utility model discloses basic embodiment and each further alternative can the independent assortment in order to form a plurality of embodiments, is the utility model discloses can adopt and claim the embodiment of protection. In the scheme of the utility model, each selection example can be combined with any other basic examples and selection examples at will.

The above description is only exemplary of the present invention and should not be taken as limiting the scope of the present invention, as any modifications, equivalents, improvements and the like made within the spirit and principles of the present invention are intended to be included within the scope of the present invention.

Claims

1. A disposable blood separation device comprising a separation bag (100) and a bowl (200), characterized in that: the blood plasma separating device is characterized in that a conical separating groove is formed in the rotary drum (200), the separating bag (100) is arranged in the separating groove, a primary separating cavity (1) and a secondary separating cavity (2) are arranged in the separating bag (100), the whole blood inlet pipe (11) extends into the primary separating cavity (1), the plasma outlet pipe (12) extends to the top of the primary separating cavity (1), the blood cell outlet pipe (13) extends to the bottom of the primary separating cavity (1), the PRP outlet pipe (21) extends to the bottom of the secondary separating cavity (2), the poor platelet plasma outlet pipe (22) extends to the top of the secondary separating cavity (2), and the plasma inlet pipe (23) extends into the secondary separating cavity (2).

2. The disposable blood separation set of claim 1 wherein: the separation bag (100) is of a fan-shaped structure.

3. The disposable blood separation device of claim 1 or 2, wherein: the primary separation cavity (1) and the secondary separation cavity (2) are respectively positioned at two sides of the separation bag (100).

4. The disposable blood separation set of claim 1 wherein: the drum (200) is internally provided with a separation groove which is annular along the circumferential direction.

5. The disposable blood separation set of claim 1 or 4, wherein: the rotary drum (200) comprises a rotary drum upper round table (3), a rotary drum lower round table (4), a rotary drum inner wall (6) and a rotary drum outer wall (7), wherein the rotary drum upper round table (3) is respectively connected with the upper end of the rotary drum inner wall (6) and the upper end of the rotary drum outer wall (7), the rotary drum inner wall (6) and the rotary drum outer wall (7) are round table-shaped cross sections, the rotary drum lower round table (4) is respectively connected with the lower end of the rotary drum inner wall (6) and the lower end of the rotary drum outer wall (7), and a separating groove is formed in front of the rotary drum upper round table (3), the rotary drum lower round table (4), the rotary drum inner wall (6) and the rotary drum outer wall (7).

6. The disposable blood separation set of claim 1 wherein: the separation bag (100) and the rotary drum (200) are provided with corresponding fixing holes (5), and the separation bag (100) is fixed on the rotary drum (200) through fixing buckles and the fixing holes (5).

7. The disposable blood separation set of claim 1 wherein: the bottom of rotary drum (200) be equipped with the support opening, the top of rotary drum (200) is equipped with the support installation department.

8. The disposable blood separation set of claim 1 wherein: the whole blood inlet pipe (11) extends to the middle part of the primary separation cavity (1), and the plasma inlet pipe (23) extends to the middle part of the secondary separation cavity (2).

9. The disposable blood separation set of claim 1, wherein: the PRP outlet pipe (21) and the poor platelet plasma inlet pipe (24) jointly extend to the bottom port (25) of the secondary separation cavity (2).

10. The disposable blood separation set of claim 9 wherein: the platelet concentration monitor is opposite to the bottom port (25), and the platelet concentration monitor is in linkage with a valve at the outlet end of the poor platelet plasma inlet pipe (24) through a controller.