CN210583236U - Clinical continuous blood component centrifugal separator - Google Patents

Abstract

The utility model relates to the field of medical equipment, and discloses a clinical continuous blood component centrifugal separator, which is provided with a roller below a frame, and the upper surface of the frame is provided with a first blood pump, a second blood pump, an anticoagulant pump, a blood slurry pump, a first centrifugal machine, a second centrifugal machine, a plurality of pressure detectors, a plurality of pipeline detectors, a plurality of air detectors and a plurality of clamping valves; first centrifuge and second centrifuge are located the axis, and first centrifuge and the installation of one side of second centrifuge first blood pump, second blood pump and anticoagulant pump, the opposite side installation of first centrifuge and second centrifuge pipeline detector and plasma pump. The utility model discloses a two sets of centrifuges in with exclusive consumptive material pipeline separate the cup cooperation and adopt centrifugal technology to separate blood into hematopoiesis and plasma in succession, and blood separation can go on in succession, has shortened the time of blood separation treatment greatly. And functional components such as a heater, a cuff joint, an electronic scale, an air detector, a clamping valve, a touch screen and the like are integrated, so that the intelligence and the safety of the equipment are enhanced.

Description

Clinical continuous blood component centrifugal separator

Technical Field

The utility model relates to the field of medical equipment, concretely relates to be used for clinical continuous type blood composition centrifuge.

Background

The blood purification therapy is a clinical treatment technology developed by technologies such as hemodialysis and exsanguination, is rapidly developed in the late twentieth century, and becomes an indispensable treatment method in clinical practice.

A blood purification system generally comprises an extracorporeal circuit, which comprises a blood outflow circuit and a blood return circuit, and a blood purification device connected to the extracorporeal circuit. In the process of blood purification treatment, blood is led out of a human body through the blood outflow pipeline, purified by the blood purification device and then returned to the human body through the blood backflow pipeline, so that substances such as pathogenic factors in the blood are removed.

The core technology in blood purification therapy is the separation of blood components, and currently, the mainstream separation technologies include a centrifugal separation technology, a membrane separation technology, and an adsorption separation technology.

The membrane separation technology is to use a filter made of hollow fiber membranes with certain pore sizes to fill and separate substances with different molecular weights, and the commonly used filters include a hemodialyzer, a plasma separator and a plasma component separator. The membrane separation technology has the advantages of high separation efficiency, easy adjustment of electrolyte balance and the like. However, the membrane separation technology has the disadvantages of relative specificity, and cannot give consideration to target substances with different molecular weights and different hydrophilic and hydrophobic properties, and repeated treatment is required, so that the treatment cost is increased, and the tolerance of patients is also reduced sharply.

The adsorption separation technology is that the adsorbent is filled in an adsorber to make a disposable sterile medical apparatus, then the blood is led out from the human body and passes through an adsorption column in a blood perfusion or plasma perfusion mode to specifically or relatively specifically adsorb one or more pathogenic substances, and the commonly used adsorber comprises a disposable hemoperfusion device, a disposable endotoxin adsorber, a disposable plasma bilirubin adsorber, a DNA immunoadsorption column, a blood fat adsorption column, a leukocyte adsorption column and the like. The adsorption separation technique has an advantage of being able to form relatively specific adsorption separation and removal of a target substance, but the adsorption separation has a disadvantage that the electrolyte balance is difficult to adjust.

For some diseases, the pathogenic substances are usually composed of several substances with different properties, even hundreds of them, which brings the challenge to separate blood components and the pathogenic substances in plasma by using a certain separation technology alone. Therefore, it has been an important research direction in the field to combine the advantages of centrifugal separation, membrane separation and adsorption separation techniques and to comprehensively utilize the advantages of the three.

There is currently no continuous clinical blood component centrifuge available on the market for centrifugal separation technology. Can separate specific components of blood, thus being capable of carrying out advanced blood component treatment technologies such as plasmapheresis, erythrocyte removal, leukopenia, thrombopenia, blood fat removal, artificial liver treatment and the like.

SUMMERY OF THE UTILITY MODEL

An object of the utility model is to provide a continuous type blood composition centrifuge for it is clinical utilizes centrifugal separation technique separation blood, and consumptive materials such as cooperation continuous type blood composition centrifuge and treatment system purify blood treatment disease.

In order to achieve the above object, the utility model provides a following technical scheme:

a continuous blood component centrifugal separator for clinical use comprises a frame and is characterized in that rollers are mounted below the frame, and a first blood pump, a second blood pump, an anticoagulant pump, a blood pump, a first centrifugal machine, a second centrifugal machine, a plurality of pressure detectors, a plurality of pipeline detectors, a plurality of air detectors and a plurality of clamping valves are mounted on the upper surface of the frame; the first centrifuge and the second centrifuge are positioned on an axis, the first blood pump, the second blood pump and the anticoagulant pump are installed on one side of the first centrifuge and the second centrifuge, and the pipeline detector and the plasma pump are installed on the other side of the first centrifuge and the second centrifuge;

in the present invention, the pressure detector includes a first pressure detector 17 and a second pressure detector 32, and the first pressure detector and the second pressure detector are respectively installed on the side of the frame; the pipeline detector comprises a first pipeline detector and a second pipeline detector, the first pipeline detector corresponds to the first centrifugal machine, and the second pipeline detector corresponds to the second centrifugal machine; the air detector comprises a first air detector, a second air detector, a third air detector and a fourth air detector, wherein the air detector is used for detecting whether the pipeline contains air or not.

The utility model also comprises a first hanging rack, a second hanging rack, a first therapeutic device fixing seat and a second therapeutic device fixing seat; the first hanging rack and the second hanging rack are respectively arranged on two sides of the rack; the first therapeutic device fixing seat and the second therapeutic device fixing seat are positioned on the same side of the rack.

The utility model discloses in, install in the frame and keep plasma return line or blood return line homothermal heater, this heater makes the temperature of the plasma or the blood of purification keep unanimous with human body temperature, lets the patient feel more comfortable.

The utility model discloses in, install the sleeve area joint that is used for the sleeve area in the frame, can fill the gassing to sleeve area through sleeve area joint, real time monitoring human blood pressure is by equipment sensor real time monitoring and suggestion.

The utility model discloses in, still install the electronic scale that is used for weighing plasma in the frame, this electronic scale when plasma is gathered, the plasma weight that can real time monitoring has gathered.

Compared with the prior art, the beneficial effects of the utility model are that:

the utility model discloses utilize two sets of separation cup cooperations in two sets of centrifuge and the exclusive consumptive material pipeline to adopt centrifugal technology to separate into hematopoiesis and plasma in succession, blood separation can go on in succession, has shortened the time of blood separation treatment greatly.

The utility model is provided with a pressure detector, the pressure detector is matched with a pressure detector connector in a special consumable pipeline to detect the blood pressure value in the extracorporeal circulation pipeline in real time, and the blood pressure value is used for judging whether the purification system is abnormal or not and judging whether the patient has over-high or over-low blood pressure or not;

the utility model relates to a have ultrasonic air detector, whether ultrasonic air detector contains the air in the external circulation pipeline of real-time detection, can effectively prevent unexpected the emergence.

The utility model is provided with a heater, which heats a section of plasma or blood return pipeline close to the human body in the extracorporeal circulation pipeline, so that the temperature of the purified plasma or blood is consistent with the temperature of the human body, and the patient feels more comfortable.

Drawings

Fig. 1 is a schematic view of a first structure provided by the present invention;

fig. 2 is a second schematic structural diagram provided by the present invention;

reference numerals: 1 is a control screen, 2 is a first clamping stop valve, 3 is a second clamping stop valve, 4 is a first air detector, 5 is a first blood pump, 6 is a third clamping stop valve, 7 is a first centrifuge, 8 is a fourth clamping stop valve, 9 is a second air detector, 10 is a second blood pump, 11 is a third air detector, 12 is a fifth clamping stop valve, 13 is a fourth air detector, 14 is an anticoagulant pump, 15 is a second centrifuge, 16 is an electronic scale, 17 is a first pressure detector, 18 is a first hanging nail, 19 is a second hanging nail, 20 is a first filter fixing support, 21 is a second filter fixing support, 22 is a first therapeutic device fixing seat, 23 is a third hanging nail, 24 is a second therapeutic device fixing seat, 25 is a fourth hanging nail, 26 is a storage box, 27 is a fifth air detector, 28 is a sixth air detector, 29 is a first filter fixing support, 30 is a second filter fixing support, 31 is a cuff connector, 32 is a second pressure detector, 33 is a pipeline heater, 34 is a first third filter fixing support, 35 is a second third filter fixing support, 36 is a sixth clamping stop valve, 37 is a first hanging frame, 38 is a seventh clamping stop valve, 39 is an eighth clamping stop valve, 40 is a second hanging frame, 41 is a ninth clamping stop valve, 42 is a second pipeline detector, 43 is a tenth clamping stop valve, 44 is a blood pump, 45 is a first pipeline detector, 46 is an eleventh clamping stop valve, 47 is a twelfth clamping stop valve, and 48 is a case.

FIG. 3 is a schematic diagram of a dedicated consumable structure;

the reference signs are: 1-1 is a first liquid stopping clip, 1-2 is an anticoagulant pump tube, 1-3 is an anticoagulant puncture outfit component, 1-4 is a first liquid stopping clip, 1-5 is a sample reserving bag, 1-6 is a second filter, 1-7 is a second pressure detector connector, 1-8 is a first blood pump tube, 1-9 is a first centrifugal cup, 1-10 is a second blood pump tube, 1-11 is a second centrifugal cup, 1-12 is a blood plasma bag, 1-13 is a second liquid stopping clip, 1-14 is a physiological saline puncture outfit component, 1-15 is a third liquid stopping clip, 1-16 is a blood plasma pump tube, 1-17 is a first pressure monitor connector, 1-18 is a first filter, 1-19 is a fourth liquid stopping clip, 1-20 is a first-stage treatment device, 1-21 is a fifth liquid stopping clip, 1-4 is a fifth liquid stopping clip, 1-5 is a sample reserving bag, 1-6 is a second filter, 1-7 is a second pressure detector connector, 1-13, 1-22 is a second-stage therapeutic device, 1-23 is a sixth liquid stopping clip, 1-24 is a waste liquid bag, 1-25 is a third filter, 1-26 is a seventh liquid stopping clip, 1-27 is a blood cell reinfusion bag, 1-28 is a blood transfusion device component, and 1-29 is a machine blood collector.

2-27, 2-28, 2-11, 2-46, 2-6, 2-8, 2-9, 2-42, 2-41, 2-38, 2-39, and 2-39 are the third air detector detection bits, the second pinch valve clamp stop bit, the third pinch valve clamp stop bit, 2-8, the fourth pinch valve clamp stop bit, 2-8, 2-9, the second air detector detection bit, 2-42, 2-41, 2-46, 2-43, the tenth pinch valve clamp stop bit, 2-36, the sixth pinch valve clamp stop bit, 2-38, the seventh pinch valve clamp stop bit, and 2-39, the eighth pinch valve clamp stop bit, 2-33 are heating positions of the pipeline heater, 2-13 are detection positions of the fourth air detector, and 2-12 are clamping positions of the fifth clamping stop valve.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

Example the operation of the installation and separation of the dedicated consumables will be described with reference to FIGS. 1, 2 and 3

Installation of consumables:

the anticoagulant pump pipe 1-2 is installed in the anticoagulant pump 14, the first air detector detects the position 2-4, and the first air detector 4 detects whether air or air bubbles exist in the pipeline; the second air detector detects the positions 2-9, and the second air detector 9 detects whether air or air bubbles exist in the pipeline; the third air detector detects the positions 2-11, and the second air detector 11 detects whether air or air bubbles exist in the pipeline; third air detector detection bits 2-13 the third air detector 13 detects whether air or air bubbles are present in the pipeline; the fourth air detector detects the positions 2-13, and the fourth air detector 13 detects whether air or air bubbles exist in the pipeline; fifth air detector detection bits 2-27 the presence of air or air bubbles in the pipeline is detected by the fifth air detector 27; sixth air detector detection bits 2-28 the presence of air or air bubbles in the pipeline is detected by the sixth air detector 28.

The first clamping stop valve position 2-2 performs opening/closing action on the pipeline through the first clamping stop valve 2, and the second clamping stop valve position 2-3 performs opening/closing action on the pipeline through the second clamping stop valve 2; the third clamping stop valve position 2-6 is used for opening/closing the pipeline by the third clamping stop valve 6; the fourth clamping stop valve position 2-8 is used for opening/closing the pipeline by the fourth clamping stop valve 8; the fifth clamping stop valve position 2-12 is used for opening/closing the pipeline by the fifth clamping stop valve 12; the sixth clamping stop valve positions 2-36 are used for opening/closing the pipeline by the sixth clamping stop valve 36; the seventh pinch-off valve position 2-38 is used for opening/closing the pipeline by the seventh pinch-off valve 38; the eighth pinch-stop valve position 2-39 is used for opening/closing the pipeline by the eighth pinch-stop valve 39; the ninth clamping valve position 2-41 is used for opening/closing the pipeline by the ninth clamping valve 41; the tenth pinch-off valve position 2-43 is used for opening/closing the pipeline by the tenth pinch-off valve 43; the eleventh pinch-off valve 49 of the eleventh pinch-off valve position 2-49 opens/closes the pipeline; the twelfth pinch-off valve position 2-46 is configured to open/close the pipe by the twelfth pinch-off valve 46.

The second pipeline detector 2-42 monitors the liquid condition in the pipeline by the second pipeline detector 42; the first pipeline detector 2-45 monitors the liquid condition inside the pipeline by the first pipeline detector 45.

The first filter 1-18 is arranged on the first filter fixing seat support 20 and the second filter fixing seat support 21, and the first pressure monitor connector 1-17 connected with the first filter 1-18 is arranged on the first pressure monitor 17; the second filter 1-6 is arranged on the first filter fixing seat support 29 and the second filter fixing seat support 30, and the second pressure monitor connector 1-6 connected with the second filter 1-6 is arranged on the first pressure monitor 6. The pipelines of the heating positions 2-13 of the heater are placed into the heater 13, so that the temperature of the purified blood plasma or blood is kept consistent with the temperature of a human body, and a patient feels more comfortable. The plasma bags 1-12 are hung on an electronic scale 16. The first-level therapeutic device 1-20 is arranged on the first therapeutic device fixing seat 22, and the second-level therapeutic device 1-22 is arranged on the second therapeutic device fixing seat 24. A first blood pump pipe 1-8 is arranged on a first blood pump 5, a second blood pump pipe 1-10 is arranged in a second blood pump 10, and an anticoagulant pump pipe 1-2 is arranged in an anticoagulant pump 14. The plasma pump tubing 1-16 is mounted within the plasma pump tubing 44.

The explanation is made with reference to FIG. 1, FIG. 2 and FIG. 3

Firstly, a matched consumable operation machine is assembled, at the moment, except for the opening of the second clamping valve 2, the other clamping valves are all in a closed state, according to a prompt, the third liquid stopping clamp 1-15 is opened, the sixth liquid stopping clamp 1-23 is opened, the first-stage therapeutic device 1-20 and the second-stage therapeutic device 1-22 are washed by normal saline, or the first-stage therapeutic device and the second-stage therapeutic device are washed by opening and closing the combination relationship of the fourth hemostatic clamp 1-19 and the fifth liquid stopping clamp 1-21, the washed liquid enters a waste liquid bag, after the washing is finished, the third liquid stopping clamp 1-15 is closed, the sixth liquid stopping clamp 1-23 is closed, the seventh hemostatic clamp 1-26 is opened, a cuff connected to the cuff interface 31 is bound to a blood sampling arm of a human body for monitoring the blood pressure of the human body according to the prompt, at the moment, the second clamping valve 2-3 is opened, the twelfth clamping valve 2-46 is opened, the seventh pinch-off valve 2-38 is open and the remaining pinch-off valves are closed. The first centrifuge 7 starts to operate, then the blood vessel puncture of the human body is carried out, the human blood enters the blood collector for machine, the first hemostatic clamp 1-1 is opened, meanwhile, the first blood pump 5 and the anticoagulant pump 14 start to operate according to the set proportion to provide anticoagulant, the explanation is provided by combining the figure 1 and the figure 3, the whole blood at the position shown in the figure 1 starts to flow to the outside of the body under the action of the first blood pump 5, the second liquid stopping clamp 1-4 is opened to enter a sample reserving bag for subsequent blood detection, the second liquid stopping clamp 1-4 is closed after the sample reserving is finished, the blood mixed by the whole blood and the anticoagulant sequentially passes through the fifth air detector position 2-27, the sixth air detector position 2-28, the second filter 1-6, the second clamping stop valve position 2-3, the first air detector detection position 2-4, the first blood pump pipe 1-8 and the first centrifuge cup 1-9, according to the specific gravity difference between cells, plasma and blood cells are separated by centrifugation, and the separated plasma passes through the first pipeline detector 2-45 and the eleventh pinch valve position 2-46 along the pipeline and enters the plasma bag 1-12. When the plasma and blood cell interface reaches the position of the second pipeline detector 45, the first pipeline detector 45 sends a signal, the eleventh pinch valve 46 is closed, the second pinch valve 2-3 is closed, the first centrifugal machine 7 stops running, the first blood pump 1-8 reversely rotates, the equipment starts to return blood cells in the first centrifugal cup 1-9 to the human body, and at the moment, the blood cells sequentially pass through the first blood pump pipe 1-8, the first air detector detection bit 2-4, the first pinch valve position 2-2, the sixth pinch valve position 2-36, the third filter 1-25, the blood cell return bag 1-27, the pipeline heater position 2-33, the fourth air detector 2-13, the fifth pinch valve 2-12, the blood transfusion assembly 1-28 and finally return to the human body.

The further passage is started immediately after the first centrifuge 7 is stopped, and when the first centrifuge 7 is stopped, the second centrifuge 15 is started simultaneously and the second blood pump 10 is started. At this time, the eleventh pinch-off valve 46 is closed, the second pinch-off valve 2-3 is closed, the fourth pinch-off valve 8 is closed, and the remaining pinch-off valves are in an open state. Whole blood starts to flow to the outside of the body under the action of a second blood pump 10, an anticoagulant pump 14 starts to operate according to a set proportion to provide anticoagulant, the blood mixed with the anticoagulant sequentially passes through a fifth air detector position 2-27, a sixth air detector position 2-28, a second filter 1-6, a third pinch valve position 2-6, a second air detector detection position 2-9, a second blood pump pipe 1-10 and a second centrifugal cup 1-11, plasma and blood cells are centrifugally separated according to specific gravity difference among cells, and the separated plasma passes through a second pipeline detector 2-42 and a ninth pinch valve position 2-41 along a pipeline and enters a plasma bag 1-12. When the plasma and blood cell interface reaches the position of the second pipeline detector 42, the second pipeline detector 42 sends a signal, the ninth pinch valve 41 is closed, the third pinch valve 2-6 is closed, the second centrifuge 15 stops running, the second blood pump 10 rotates reversely, the device starts to feed back the blood cells in the second centrifuge cup 1-11 to the human body, and the blood cells sequentially pass through the second blood pump pipe 1-10, the second air detector detection position 2-9, the first pinch valve position 2-8, the sixth pinch valve position 2-36, the third filter 1-25, the blood cell feedback bag 1-27, the pipeline heater position 2-33, the fourth air detector 2-13, the fifth pinch valve 2-12, the blood transfusion device assembly 1-28 and finally return to the human body. The previous actions are then repeated, thus achieving a continuous acquisition function through the two centrifuges and the open and close logic of the valves.

When the plasma in the plasma bag 1-12 reaches a set value, the tenth pinch valve 43 is started, the plasma pump 44 is started to run, the plasma in the plasma bag is pumped in the direction of the plasma pump, the plasma sequentially flows through the tenth pinch valve position 2-43, the plasma pump pipe 1-16, the first filter 1-18, the first-stage therapeutic device 1-20, the second-stage therapeutic device 1-22, the seventh pinch valve position 2-38, the third filter 1-25, the cell feedback bag 1-27 and the blood cells are mixed and then returned to the human body together, and thus continuous feedback of the continuous equipment is realized.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims (5)

1. A continuous blood component centrifugal separator for clinical use comprises a frame and is characterized in that rollers are mounted below the frame, and a first blood pump, a second blood pump, an anticoagulant pump, a blood pump, a first centrifugal machine, a second centrifugal machine, a plurality of pressure detectors, a plurality of pipeline detectors, a plurality of air detectors and a plurality of clamping valves are mounted on the upper surface of the frame; first centrifuge and second centrifuge are located the axis, and first centrifuge and the installation of one side of second centrifuge first blood pump, second blood pump and anticoagulant pump, the opposite side installation of first centrifuge and second centrifuge pipeline detector and plasma pump.

2. The continuous clinical blood component centrifuge of claim 1, wherein the continuous blood collection and continuous separation are achieved by the logical cooperation of the start and stop of the first and second centrifuges and the opening and closing of the pinch valves.

3. The continuous clinical blood component centrifuge of claim 1, wherein the pressure probe comprises a first pressure probe and a second pressure probe, the first pressure probe and the second pressure probe being mounted to the frame side, respectively; the pipeline detector comprises a first pipeline detector and a second pipeline detector, the first pipeline detector corresponds to the first centrifugal machine, and the second pipeline detector corresponds to the second centrifugal machine; the air detector includes first to fifth air detectors.

4. The continuous clinical blood component centrifuge of claim 1, further comprising a first hanger, a second hanger, a first therapeutic device holder, a second therapeutic device holder; the first hanging rack and the second hanging rack are respectively arranged on two sides of the rack; the first therapeutic device fixing seat and the second therapeutic device fixing seat are positioned on the same side of the rack.

5. The continuous clinical blood component centrifuge as claimed in claim 1, wherein a heater for keeping a plasma return line or a blood return line at a constant temperature, a cuff adapter for a cuff, and an electronic scale for weighing plasma are installed on the housing.

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