CN105451818A - 治疗涉及cxcl12活性的疾病的维生素d受体激动剂 - Google Patents

治疗涉及cxcl12活性的疾病的维生素d受体激动剂 Download PDF

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Publication number
CN105451818A
CN105451818A CN201480043580.0A CN201480043580A CN105451818A CN 105451818 A CN105451818 A CN 105451818A CN 201480043580 A CN201480043580 A CN 201480043580A CN 105451818 A CN105451818 A CN 105451818A
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vdr
agonist
tumor
vitamin
gemcitabine
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M·谢尔曼
M·道恩斯
R·M·埃文斯
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Salk Institute for Biological Studies
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Salk Institute for Biological Studies
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    • A61K31/593—9,10-Secocholestane derivatives, e.g. cholecalciferol, i.e. vitamin D3
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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CN201480043580.0A 2013-06-05 2014-06-05 治疗涉及cxcl12活性的疾病的维生素d受体激动剂 Pending CN105451818A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361831515P 2013-06-05 2013-06-05
US61/831,515 2013-06-05
PCT/US2014/041063 WO2014197680A1 (en) 2013-06-05 2014-06-05 Vitamin d receptor agonists to treat diseases involving cxcl12 activity

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Publication Number Publication Date
CN105451818A true CN105451818A (zh) 2016-03-30

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CN201480043580.0A Pending CN105451818A (zh) 2013-06-05 2014-06-05 治疗涉及cxcl12活性的疾病的维生素d受体激动剂

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US (1) US9895381B2 (enExample)
EP (2) EP3473299A1 (enExample)
JP (1) JP2016530219A (enExample)
CN (1) CN105451818A (enExample)
AU (1) AU2014274864B2 (enExample)
BR (1) BR112015030518A2 (enExample)
CA (1) CA2914487A1 (enExample)
MX (1) MX2015016715A (enExample)
WO (1) WO2014197680A1 (enExample)

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CN113350362A (zh) * 2021-06-11 2021-09-07 扬州大学附属医院 维生素d受体激动剂在制备预防和/或治疗急性胰腺炎的药物中的应用
CN115515589A (zh) * 2020-02-14 2022-12-23 萨克生物研究学院 Ulk1/2抑制剂及其使用方法

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CA3019394A1 (en) * 2016-04-08 2017-10-12 X4 Pharmaceuticals, Inc. Methods for treating cancer
CN109640988A (zh) 2016-06-21 2019-04-16 X4 制药有限公司 Cxcr4抑制剂及其用途
WO2017223243A1 (en) 2016-06-21 2017-12-28 X4 Pharmaceuticals, Inc. Cxcr4 inhibitors and uses thereof
CN109562106B (zh) 2016-06-21 2023-03-21 X4 制药有限公司 Cxcr4抑制剂及其用途
WO2019023149A1 (en) 2017-07-24 2019-01-31 Salk Institute For Biological Studies USE OF BROMODOMAIN-CONTAINING PROTEIN-9 ANTAGONISTS IN ASSOCIATION WITH VITAMIN D RECEPTOR AGONISTS IN THE TREATMENT OF DIABETES
US10548889B1 (en) 2018-08-31 2020-02-04 X4 Pharmaceuticals, Inc. Compositions of CXCR4 inhibitors and methods of preparation and use
EP3851518A4 (en) * 2018-09-10 2022-06-22 Tokyo Institute of Technology PROCESS FOR THE PRODUCTION OF COLON CELLS FROM PLURIPOTENTIC STEM CELLS
JP7377486B2 (ja) * 2018-09-10 2023-11-10 国立大学法人東京工業大学 多能性幹細胞から腸細胞の作製方法
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EP4646211A1 (en) * 2023-01-06 2025-11-12 Adge Pharmaceuticals Inc. Methods for treating metabolic syndrome

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