CN105377879B - 针对衣原体属物种的疫苗 - Google Patents

针对衣原体属物种的疫苗 Download PDF

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Publication number
CN105377879B
CN105377879B CN201480026477.5A CN201480026477A CN105377879B CN 105377879 B CN105377879 B CN 105377879B CN 201480026477 A CN201480026477 A CN 201480026477A CN 105377879 B CN105377879 B CN 105377879B
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amino acid
acid sequence
polypeptide
chlamydia
seq
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CN105377879A (zh
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弗兰克·福尔曼
艾达·罗森克兰达斯
安雅·奥尔森
彼得·拉瓦茨·安德森
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Statens Serum Institut SSI
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Statens Serum Institut SSI
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/118Chlamydiaceae, e.g. Chlamydia trachomatis or Chlamydia psittaci
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/60Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031Proteins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/40Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
CN201480026477.5A 2013-03-18 2014-03-17 针对衣原体属物种的疫苗 Active CN105377879B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110407442.8A CN113185587A (zh) 2013-03-18 2014-03-17 针对衣原体属物种的疫苗

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA201300155 2013-03-18
DKPA201300155 2013-03-18
DKPA201300684 2013-12-11
DKPA201300684 2013-12-11
PCT/DK2014/000015 WO2014146663A1 (en) 2013-03-18 2014-03-17 Vaccines against chlamydia sp.

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CN105377879A CN105377879A (zh) 2016-03-02
CN105377879B true CN105377879B (zh) 2021-05-04

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CN202110407442.8A Pending CN113185587A (zh) 2013-03-18 2014-03-17 针对衣原体属物种的疫苗

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US (4) US20140275478A1 (enExample)
EP (1) EP2976355B1 (enExample)
JP (3) JP2016514713A (enExample)
CN (2) CN105377879B (enExample)
AU (1) AU2014234765B2 (enExample)
BR (1) BR112015023886B1 (enExample)
CA (1) CA2907199C (enExample)
CY (1) CY1122905T1 (enExample)
DK (1) DK2976355T3 (enExample)
ES (1) ES2781579T3 (enExample)
HR (1) HRP20200511T1 (enExample)
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PT (1) PT2976355T (enExample)
RS (1) RS60135B1 (enExample)
RU (1) RU2723046C2 (enExample)
SI (1) SI2976355T1 (enExample)
SM (1) SMT202000160T1 (enExample)
WO (1) WO2014146663A1 (enExample)

Families Citing this family (13)

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Publication number Priority date Publication date Assignee Title
JP6952603B2 (ja) 2015-02-10 2021-10-20 オハイオ・ステイト・イノベーション・ファウンデーション クラミジア活性化b細胞プラットフォーム及びその方法
CN104800841B (zh) * 2015-03-02 2019-04-02 中国农业科学院兰州兽医研究所 牦牛流产衣原体灭活疫苗及其制备方法
CA2980227A1 (en) 2015-03-24 2016-09-29 Universiteit Gent A method for the detection of chlamydia suis
AU2016349937B2 (en) * 2015-11-04 2021-09-30 University Of The Sunshine Coast Chlamydia antigens and uses thereof
WO2017083337A1 (en) 2015-11-10 2017-05-18 Ohio State Innovation Foundation Methods and compositions related to accelerated humoral affinity
NL2019320B1 (en) * 2017-03-02 2018-09-21 Biosparq B V Diagnostic method and system for diagnosis
CN110603053A (zh) * 2017-03-23 2019-12-20 俄亥俄州国家创新基金会 重组衣原体活化的b细胞平台及其使用方法
RU2721123C1 (ru) * 2019-09-26 2020-05-18 федеральное государственное бюджетное учреждение «Национальный исследовательский центр эпидемиологии и микробиологии имени почетного академика Н.Ф. Гамалеи» Министерства здравоохранения Российской Федерации Штамм рекомбинантной псевдоаденовирусной частицы, экспрессирующий химерный ген MBL-CT666 Chlamydia trachomatis, способ его получения, иммуногенная композиция для защиты от урогенитального хламидиоза человека
WO2022136508A1 (en) * 2020-12-23 2022-06-30 INSERM (Institut National de la Santé et de la Recherche Médicale) Chlamydia vaccine based on targeting momp vs4 antigen to antigen presenting cells
CN116854812B (zh) * 2022-03-23 2024-09-24 东莞市朋志生物科技有限公司 抗沙眼衣原体的抗体、检测沙眼衣原体的试剂和试剂盒
CN115975049A (zh) * 2022-11-12 2023-04-18 北京成大天和生物科技有限公司 一种沙眼衣原体重组蛋白及其制备方法和应用
AR132053A1 (es) * 2023-03-02 2025-05-21 Sanofi Pasteur Composiciones para su uso en el tratamiento de clamidia
WO2025104023A1 (en) 2023-11-13 2025-05-22 Ziphius Nv MODIFIED ALPHAVIRAL nsP3

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US5869608A (en) * 1989-03-17 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis
WO2012172042A1 (en) * 2011-06-17 2012-12-20 Universiteit Gent Vaccines for chlamydia

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US5869608A (en) * 1989-03-17 1999-02-09 The United States Of America As Represented By The Department Of Health And Human Services Nucleotide and amino acid sequences of the four variable domains of the major outer membrane proteins of Chlamydia trachomatis
WO2012172042A1 (en) * 2011-06-17 2012-12-20 Universiteit Gent Vaccines for chlamydia

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Detection of Chlamydia trachomatis-specific antibodies in human sera by recombinant major outer-membrane protein polyantigens;Per Mygind等;《Journal of Medical Microbiology》;20000630;第49卷(第5期);摘要,图2(b) *
Protective immunity against Chlamydia trachomatis genital infection induced by a vaccine based on the major outer membrane multi-epitope human papillomavirus major capsid protein L1;Wen Xu等;《Vaccine》;20110212;摘要,材料与方法2.3 HPV6bL1-Ct MOMP多表位质粒的构建 *
Vaccination with the Recombinant Major Outer Membrane Protein Elicits Antibodies to the Constant Domains and Induces Cross-Serovar Protection against Intranasal Challenge with Chlamydia trachomatis;Delia F. Tifrea等;《Infection and immunity》;20130311;第81卷(第5期);摘要 *

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Publication number Publication date
EP2976355A1 (en) 2016-01-27
CN113185587A (zh) 2021-07-30
JP7506930B2 (ja) 2024-06-27
RS60135B1 (sr) 2020-05-29
US20210205433A1 (en) 2021-07-08
AU2014234765A1 (en) 2015-10-08
US10925954B2 (en) 2021-02-23
RU2723046C2 (ru) 2020-06-08
JP7510142B2 (ja) 2024-07-03
HRP20200511T1 (hr) 2020-06-26
SI2976355T1 (sl) 2020-07-31
PT2976355T (pt) 2020-04-02
US20190099478A1 (en) 2019-04-04
SMT202000160T1 (it) 2020-05-08
JP2016514713A (ja) 2016-05-23
ES2781579T3 (es) 2020-09-03
JP2021193123A (ja) 2021-12-23
BR112015023886A2 (pt) 2017-10-24
LT2976355T (lt) 2020-04-10
BR112015023886B1 (pt) 2023-05-16
AU2014234765B2 (en) 2018-01-25
CN105377879A (zh) 2016-03-02
JP2019163253A (ja) 2019-09-26
CA2907199A1 (en) 2014-09-25
RU2015141214A (ru) 2017-04-26
DK2976355T3 (en) 2020-03-30
CY1122905T1 (el) 2021-10-29
US20250255951A1 (en) 2025-08-14
CA2907199C (en) 2023-10-17
US20140275478A1 (en) 2014-09-18
HUE048573T2 (hu) 2020-08-28
WO2014146663A1 (en) 2014-09-25
PL2976355T3 (pl) 2020-07-13
EP2976355B1 (en) 2020-01-01

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