CN105377306B - Glp-1衍生物和其用途 - Google Patents

Glp-1衍生物和其用途 Download PDF

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CN105377306B
CN105377306B CN201480035036.1A CN201480035036A CN105377306B CN 105377306 B CN105377306 B CN 105377306B CN 201480035036 A CN201480035036 A CN 201480035036A CN 105377306 B CN105377306 B CN 105377306B
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derivative
xaa
glp
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chem
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CN105377306A (zh
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S.里德茨-朗格
P.索尔伯格
J．科福伊德
I.佩特斯森
C.W.托诺伊
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Novo Nordisk AS
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CN201480035036.1A 2013-06-20 2014-06-19 Glp-1衍生物和其用途 Active CN105377306B (zh)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP13173068 2013-06-20
EP13173068.1 2013-06-20
US201361841995P 2013-07-02 2013-07-02
US61/841995 2013-07-02
EP13175092 2013-07-04
EP13175092.9 2013-07-04
US201361845647P 2013-07-12 2013-07-12
US61/845647 2013-07-12
PCT/EP2014/062952 WO2014202727A1 (en) 2013-06-20 2014-06-19 Glp-1 derivatives and uses thereof

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CN105377306A CN105377306A (zh) 2016-03-02
CN105377306B true CN105377306B (zh) 2020-03-17

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EP (1) EP3010546B1 (cg-RX-API-DMAC10.html)
JP (1) JP6475233B2 (cg-RX-API-DMAC10.html)
KR (1) KR20160021183A (cg-RX-API-DMAC10.html)
CN (1) CN105377306B (cg-RX-API-DMAC10.html)
AU (1) AU2014283221A1 (cg-RX-API-DMAC10.html)
BR (1) BR112015030948A2 (cg-RX-API-DMAC10.html)
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AU2014283221A1 (en) 2013-06-20 2015-12-03 Novo Nordisk A/S GLP-1 derivatives and uses thereof
JP6730278B2 (ja) * 2014-11-27 2020-07-29 ノヴォ ノルディスク アー／エス Ｇｌｐ−１誘導体及びその使用
EP3233898A1 (en) * 2014-12-17 2017-10-25 Novo Nordisk A/S Glp-1 derivatives and uses thereof
US10118904B2 (en) 2015-06-05 2018-11-06 Vertex Pharmaceuticals Incorporated Triazoles for the treatment of Demyelinating Diseases
AU2016379403B2 (en) 2015-12-23 2020-03-12 The Johns Hopkins University Long-acting GLP-1r agonist as a therapy of neurological and neurodegenerative conditions
CN106928343A (zh) * 2015-12-30 2017-07-07 深圳翰宇药业股份有限公司 索玛鲁肽的制备方法
WO2017149070A1 (en) 2016-03-03 2017-09-08 Novo Nordisk A/S Glp-1 derivatives and uses thereof
WO2018106641A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Pyrazoles for the treatment of demyelinating diseases
WO2018106643A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Heterocyclic azoles for the treatment of demyelinating diseases
WO2018106646A1 (en) 2016-12-06 2018-06-14 Vertex Pharmaceuticals Incorporated Aminotriazoles for the treatment of demyelinating diseases
WO2018113340A1 (zh) * 2016-12-20 2018-06-28 中国药科大学 多肽p11及其用途
SMT202200352T1 (it) 2018-04-05 2022-09-14 Sun Pharmaceutical Ind Ltd Analoghi del glp-1 innovativi
CN112312922B (zh) * 2018-06-21 2025-04-11 诺和诺德股份有限公司 用于治疗肥胖症的新型化合物
MY205905A (en) * 2018-10-22 2024-11-20 Janssen Pharmaceutica Nv Glucagon like peptide 1 (glp1)-growth differentiation factor 15 (gdf15) fusion proteins and uses thereof
MY206306A (en) * 2018-10-26 2024-12-07 Novo Nordisk As Stable semaglutide compositions and uses thereof
WO2020118843A1 (zh) * 2018-12-12 2020-06-18 四川利通科创生物医药科技有限公司 一种glp-1突变体及其制备方法和用途
CN110590934B (zh) * 2019-09-25 2020-12-08 北京乐普医药科技有限公司 一种glp-1化合物
CN111253475B (zh) * 2020-02-18 2021-03-09 江苏诺泰澳赛诺生物制药股份有限公司 Glp-1激动多肽化合物及其盐与合成方法及用途
AR122579A1 (es) * 2020-06-12 2022-09-21 Lilly Co Eli Proceso para preparar un agonista dual glp-1 / glucagón
CA3193453A1 (en) 2020-09-30 2022-04-07 Beijing Ql Biopharmaceutical Co., Ltd. Polypeptide conjugates and methods of uses
TW202620039A (zh) 2020-12-18 2026-05-16 丹麥商諾佛 儂迪克股份有限公司 Ｇｌｐ－１及澱粉素受體之共促效劑之用途
EP4323413A4 (en) 2022-03-30 2025-10-15 Beijing Ql Biopharmaceutical Co Ltd LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF
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