CN105326871A - Ultrafine wall-breaking smashing method for moringa seeds - Google Patents
Ultrafine wall-breaking smashing method for moringa seeds Download PDFInfo
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- CN105326871A CN105326871A CN201510830569.5A CN201510830569A CN105326871A CN 105326871 A CN105326871 A CN 105326871A CN 201510830569 A CN201510830569 A CN 201510830569A CN 105326871 A CN105326871 A CN 105326871A
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Abstract
The invention provides an ultrafine wall-breaking smashing method for moringa seeds, and belongs to the field of traditional Chinese medicine. The ultrafine wall-breaking smashing method for the moringa seeds is characterized by comprising the following steps: (1) smashing the moringa seeds, screening the moringa seeds through a sieve of 60 to 80 meshes, and obtaining moringa seed powder; (2) uniformly mixing sodium carboxymethyl starch and medium-chain triglyceride, wherein the mass ratio of the sodium carboxymethyl starch to the medium-chain triglyceride is preferably 8 to 2, and sodium carboxymethyl starch and medium-chain triglyceride mixed powder is obtained; (3) uniformly mixing the moringa seed powder with the sodium carboxymethyl starch and medium-chain triglyceride mixed powder, wherein the mass ratio of the moringa seed powder to the sodium carboxymethyl starch and medium-chain triglyceride mixed powder is preferably (300-200) : 1. Compared with the conventional ultrafine wall-breaking smashing method, the ultrafine wall-breaking smashing method for the moringa seeds has the advantages of short processing time, high powder preparation rate, high quercetin retention rate, high dissolving rate, small average particle size of powder and the like.
Description
Technical field
The present invention relates to a kind of moringa seeds super-micro wall-broken breaking method, belong to medical art.
Background technology
Moringa seeds is the seed of Moringa tree, has good using value in fields such as medicines and health protections, and it all has significant curative effect in reduction blood fat and blood pressure, weight-reducing, adjustment the intestines and stomach, hepatoprotective alleviating alcohol addiction and enhancing body immunity, and application is normal in powder form.
After moringa seeds micronizing, because the specific surface area of particle diameter increases, the dissolution rate of the effective ingredient such as Quercetin can be increased considerably, thus improve drug effect.Existing moringa seeds super-micro wall-broken breaking method exists that grinding time is long, flour extraction is low and the problem such as Quercetin loss rate is high.
Summary of the invention
The object of this invention is to provide a kind of moringa seeds super-micro wall-broken breaking method, to solve the problems of the technologies described above.
For foregoing invention object, the invention provides following technical scheme:
Moringa seeds super-micro wall-broken breaking method of the present invention, it is characterized in that, concrete steps are as follows:
A: pulverized by moringa seeds, crosses 60 ~ 80 mesh sieves, obtains moringa seeds powder;
B: mixed homogeneously with medium chain triglyceride by carboxymethyl starch sodium, obtains carboxymethyl starch sodium-medium chain triglyceride mixed powder;
C: mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, micronizing is to mean diameter to less than 2 microns.
The mass ratio of carboxymethyl starch sodium and medium chain triglyceride is preferably 8:2.
The mass ratio of moringa seeds powder and carboxymethyl starch sodium-medium chain triglyceride mixed powder is preferably 300 ~ 200:1.
Beneficial effect of the present invention is mainly:
Moringa seeds super-micro wall-broken breaking method of the present invention has that process time is short, flour extraction is high, Quercetin retention rate and the advantage such as dissolution rate is high and powder average particle size is little.Moringa seeds super-micro wall-broken breaking method of the present invention is unique, and be that the accident in great many of experiments finds, order by merging and the ratio of carboxymethyl starch sodium, medium chain triglyceride and moringa seeds fine powder all can not adjust.Therefore the present invention adopt composition, ratio and order of addition, be innovative point of the present invention.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but should note scope of the present invention not by any restriction of these examples.
Embodiment 1
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; By 8g carboxymethyl starch sodium and 2g medium chain triglyceride mix homogeneously, obtain carboxymethyl starch sodium-medium chain triglyceride mixed powder; Mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 1.
The moringa seeds superfine powder related data of table 1 embodiment 1
Embodiment 2
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; By 12g carboxymethyl starch sodium and 3g medium chain triglyceride mix homogeneously, obtain carboxymethyl starch sodium-medium chain triglyceride mixed powder; Mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 2.
The moringa seeds superfine powder related data of table 2 embodiment 2
Embodiment 3
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; By 9.6g carboxymethyl starch sodium and 2.4g medium chain triglyceride mix homogeneously, obtain carboxymethyl starch sodium-medium chain triglyceride mixed powder; Mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 3.
The moringa seeds superfine powder related data of table 3 embodiment 3
Comparative example 1
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; By 7g carboxymethyl starch sodium and 1.75g medium chain triglyceride mix homogeneously, obtain carboxymethyl starch sodium-medium chain triglyceride mixed powder; Mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 4.
The moringa seeds superfine powder related data of table 4 comparative example 1
Comparative example 2
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; By 13.5g carboxymethyl starch sodium and 3.375g medium chain triglyceride mix homogeneously, obtain carboxymethyl starch sodium-medium chain triglyceride mixed powder; Mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 5.
The moringa seeds superfine powder related data of table 5 comparative example 2
| Project | Mean diameter | Flour extraction | Quercetin retention rate | Quercetin dissolution rate |
| (30min) | ||||
| Moringa seeds superfine powder | 2.3 micron | 92％ | 92％ | 91％ |
Comparative example 3
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; Adopted by moringa seeds powder SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 6.
The moringa seeds superfine powder related data of table 6 comparative example 3
Comparative example 4
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; Mixed homogeneously with 10g carboxymethyl starch sodium by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 7.
The moringa seeds superfine powder related data of table 7 comparative example 4
Comparative example 5
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; Mixed homogeneously with 10g medium chain triglyceride by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 8.
The moringa seeds superfine powder related data of table 8 comparative example 5
Comparative example 6
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; Mixed homogeneously with 15g carboxymethyl starch sodium by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 9.
The moringa seeds superfine powder related data of table 9 comparative example 6
Comparative example 7
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; Mixed homogeneously with 15g medium chain triglyceride by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 10.
The moringa seeds superfine powder related data of table 10 comparative example 7
Comparative example 8
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; By 9g carboxymethyl starch sodium and 1g medium chain triglyceride mix homogeneously, obtain carboxymethyl starch sodium-medium chain triglyceride mixed powder; Mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 11.
The moringa seeds superfine powder related data of table 11 comparative example 8
Comparative example 9
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; By 7g carboxymethyl starch sodium and 3g medium chain triglyceride mix homogeneously, obtain carboxymethyl starch sodium-medium chain triglyceride mixed powder; Mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 12.
The moringa seeds superfine powder related data of table 12 comparative example 9
Comparative example 10
3kg moringa seeds is pulverized, crosses 60 ~ 80 mesh sieves, obtain moringa seeds powder; By 5g carboxymethyl starch sodium and 5g medium chain triglyceride mix homogeneously, obtain carboxymethyl starch sodium-medium chain triglyceride mixed powder; Mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, adopt SWFJ micronizing unit to pulverize 1 hour, gained powder measures mean diameter, flour extraction, Quercetin retention rate and dissolution rate, the results are shown in Table 13.
The moringa seeds superfine powder related data of table 13 comparative example 10
The present invention has screened a large amount of prescriptions; find: only in scope; namely the mass ratio of carboxymethyl starch sodium and medium chain triglyceride is preferably 8:2; and the mass ratio of moringa seeds powder and carboxymethyl starch sodium-medium chain triglyceride mixed powder is preferably 300 ~ 200:1; can realize the pulverizing of less than 2 microns, simultaneously flour extraction or Quercetin retention rate or dissolution rate are all higher than 95%.And not according to ratio of the present invention, even if the mass ratio as carboxymethyl starch sodium and medium chain triglyceride is 8:2, but the mass ratio of moringa seeds powder and carboxymethyl starch sodium-medium chain triglyceride mixed powder is not 300 ~ 200:1, as shown in comparative example 1 and 2, its result particle diameter is greater than 2 microns, and simultaneously flour extraction or Quercetin retention rate or dissolution rate are all lower than 95%.And comparative example 3-10, the non-8:2 of mass ratio of carboxymethyl starch sodium and medium chain triglyceride, even do not add carboxymethyl starch sodium and medium chain triglyceride, its result shows, add carboxymethyl starch sodium-medium chain triglyceride mixed powder particle diameter to be diminished, do not add rear particle diameter about more than 5 microns, its indices is not up to standard.
Therefore: as can be seen from the above embodiments, in moringa seeds super-micro wall-broken crushing process, application carboxymethyl starch sodium and medium chain triglyceride are as assisted comminution material, significantly can improve crush efficiency, and have that flour extraction is high, Quercetin retention rate and the advantage such as dissolution rate is high and powder average particle size is little.Wherein when the mass ratio of carboxymethyl starch sodium and medium chain triglyceride is 8:2, when the mass ratio of moringa seeds powder and carboxymethyl starch sodium-medium chain triglyceride mixed powder is 300 ~ 200:1, be key factor, it has best crushing effect, has very large market popularization value.
Claims (3)
1. a moringa seeds super-micro wall-broken breaking method, is characterized in that, concrete steps are as follows:
A: pulverized by moringa seeds, crosses 60 ~ 80 mesh sieves, obtains moringa seeds powder;
B: mixed homogeneously with medium chain triglyceride by carboxymethyl starch sodium, obtains carboxymethyl starch sodium-medium chain triglyceride mixed powder;
C: mixed homogeneously with carboxymethyl starch sodium-medium chain triglyceride mixed powder by moringa seeds powder, micronizing is to mean diameter to less than 2 microns.
2. moringa seeds super-micro wall-broken breaking method according to claim 1, is characterized in that, the mass ratio of carboxymethyl starch sodium and medium chain triglyceride is 8:2.
3. moringa seeds super-micro wall-broken breaking method according to claim 1, is characterized in that, the mass ratio of moringa seeds powder and carboxymethyl starch sodium-medium chain triglyceride mixed powder is preferably 300 ~ 200:1.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105030896A (en) * | 2015-08-18 | 2015-11-11 | 郑红芹 | Ultrafine wall-breaking grinding method for salviae miltiorrhizae |
| CN105055475A (en) * | 2015-08-18 | 2015-11-18 | 郑红芹 | Ultramicro wall-breaking smashing method for panax notoginseng |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105030896A (en) * | 2015-08-18 | 2015-11-11 | 郑红芹 | Ultrafine wall-breaking grinding method for salviae miltiorrhizae |
| CN105055475A (en) * | 2015-08-18 | 2015-11-18 | 郑红芹 | Ultramicro wall-breaking smashing method for panax notoginseng |
Non-Patent Citations (1)
| Title |
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| 巴晓革等: "微粉中药制剂添加助剂的制备工艺研究", 《齐鲁药事》 * |
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Application publication date: 20160217 |