CN105283559A - 短端粒丰度的量度 - Google Patents

短端粒丰度的量度 Download PDF

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Publication number
CN105283559A
CN105283559A CN201480029826.9A CN201480029826A CN105283559A CN 105283559 A CN105283559 A CN 105283559A CN 201480029826 A CN201480029826 A CN 201480029826A CN 105283559 A CN105283559 A CN 105283559A
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sequence
telomere
primer
abundance
extension
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Chinese (zh)
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C·哈利
J·林
Y·胡
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Telomere Diagnostics Inc
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Telomere Diagnostics Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CN201480029826.9A 2013-05-22 2014-05-22 短端粒丰度的量度 Pending CN105283559A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361826484P 2013-05-22 2013-05-22
US61/826,484 2013-05-22
PCT/US2014/039110 WO2014190138A2 (en) 2013-05-22 2014-05-22 Measures of short telomere abundance

Publications (1)

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CN105283559A true CN105283559A (zh) 2016-01-27

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US (2) US10316366B2 (enExample)
EP (1) EP2999800B1 (enExample)
JP (1) JP6546158B2 (enExample)
CN (1) CN105283559A (enExample)
AU (1) AU2014268510A1 (enExample)
CA (1) CA2912216A1 (enExample)
ES (1) ES2762860T3 (enExample)
HK (1) HK1220737A1 (enExample)
MX (1) MX2015015891A (enExample)
WO (1) WO2014190138A2 (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106480218A (zh) * 2016-12-13 2017-03-08 浙江指针基因科技有限公司 一种基于qPCR法检测白细胞端粒长度的方法
CN107164365A (zh) * 2017-06-16 2017-09-15 广州普麦健康咨询有限公司 应用三代测序技术检测染色体端粒dna全长的方法
CN112029841A (zh) * 2019-06-03 2020-12-04 香港中文大学 定量端粒长度和基因组基序的方法
CN113557307A (zh) * 2018-12-26 2021-10-26 生命长度有限公司 端粒相关变量的测定方法及其在端粒相关疾病的诊断和/或预后中的用途
CN113862336A (zh) * 2021-11-03 2021-12-31 天津医科大学 一种基于单基因校正的高通量斑点杂交端粒长度检测方法
CN117230171A (zh) * 2023-11-13 2023-12-15 元码基因科技（北京）股份有限公司 端粒扩增子测序用试剂盒及预文库构建方法
CN117248003A (zh) * 2023-11-13 2023-12-19 元码基因科技（北京）股份有限公司 用于完整端粒扩增子测序的组合物、预文库及其构建方法

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CN107083444B (zh) 2008-12-22 2023-03-14 犹他大学研究基金会 单色多重定量pcr
EP2999800B1 (en) 2013-05-22 2019-09-25 Telomere Diagnostics Inc. Measures of short telomere abundance
AU2015372584A1 (en) * 2014-12-30 2017-06-29 Telomere Diagnostics, Inc. Multiplex quantitative PCR
US10604794B2 (en) 2017-05-10 2020-03-31 The Board Of Regents Of The University Of Texas System Method to measure the shortest telomeres
US11227691B2 (en) 2019-09-03 2022-01-18 Kpn Innovations, Llc Systems and methods for selecting an intervention based on effective age
US11250337B2 (en) 2019-11-04 2022-02-15 Kpn Innovations Llc Systems and methods for classifying media according to user negative propensities
CN117230169B (zh) * 2023-11-13 2024-02-13 元码基因科技（北京）股份有限公司 用于长片段端粒序列测序的接头、预文库及其构建方法

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106480218A (zh) * 2016-12-13 2017-03-08 浙江指针基因科技有限公司 一种基于qPCR法检测白细胞端粒长度的方法
CN107164365A (zh) * 2017-06-16 2017-09-15 广州普麦健康咨询有限公司 应用三代测序技术检测染色体端粒dna全长的方法
CN107164365B (zh) * 2017-06-16 2020-11-27 广州普麦健康咨询有限公司 应用三代测序技术检测染色体端粒dna全长的方法
CN113557307A (zh) * 2018-12-26 2021-10-26 生命长度有限公司 端粒相关变量的测定方法及其在端粒相关疾病的诊断和/或预后中的用途
CN113557307B (zh) * 2018-12-26 2024-05-28 生命长度有限公司 端粒相关变量的测定方法及其在端粒相关疾病的诊断和/或预后中的用途
CN112029841A (zh) * 2019-06-03 2020-12-04 香港中文大学 定量端粒长度和基因组基序的方法
CN112029841B (zh) * 2019-06-03 2024-02-09 香港中文大学 定量端粒长度和基因组基序的方法
CN113862336A (zh) * 2021-11-03 2021-12-31 天津医科大学 一种基于单基因校正的高通量斑点杂交端粒长度检测方法
CN117230171A (zh) * 2023-11-13 2023-12-15 元码基因科技（北京）股份有限公司 端粒扩增子测序用试剂盒及预文库构建方法
CN117248003A (zh) * 2023-11-13 2023-12-19 元码基因科技（北京）股份有限公司 用于完整端粒扩增子测序的组合物、预文库及其构建方法
CN117248003B (zh) * 2023-11-13 2024-04-12 元码基因科技（北京）股份有限公司 用于完整端粒扩增子测序的组合物、预文库及其构建方法
CN117230171B (zh) * 2023-11-13 2024-04-12 元码基因科技（北京）股份有限公司 端粒扩增子测序用试剂盒及预文库构建方法

Also Published As

Publication number Publication date
EP2999800B1 (en) 2019-09-25
JP6546158B2 (ja) 2019-07-17
US10316366B2 (en) 2019-06-11
AU2014268510A1 (en) 2015-11-26
WO2014190138A2 (en) 2014-11-27
US20160090630A1 (en) 2016-03-31
WO2014190138A3 (en) 2015-02-26
EP2999800A4 (en) 2017-01-04
MX2015015891A (es) 2016-06-02
JP2016521548A (ja) 2016-07-25
EP2999800A2 (en) 2016-03-30
ES2762860T3 (es) 2020-05-26
HK1220737A1 (zh) 2017-05-12
US20190382841A1 (en) 2019-12-19
CA2912216A1 (en) 2014-11-27

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