CN105263488A - 含卡巴拉汀的经皮给药系统 - Google Patents

含卡巴拉汀的经皮给药系统 Download PDF

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Publication number
CN105263488A
CN105263488A CN201480016186.8A CN201480016186A CN105263488A CN 105263488 A CN105263488 A CN 105263488A CN 201480016186 A CN201480016186 A CN 201480016186A CN 105263488 A CN105263488 A CN 105263488A
Authority
CN
China
Prior art keywords
transdermal delivery
delivery system
rivastigmine
ester
delivery systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201480016186.8A
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English (en)
Chinese (zh)
Inventor
柳济弼
Y·约瑟夫·莫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Royal Pharmaceutical Group
Original Assignee
Nal Pharmaceuticals Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nal Pharmaceuticals Group Ltd filed Critical Nal Pharmaceuticals Group Ltd
Publication of CN105263488A publication Critical patent/CN105263488A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Inorganic Chemistry (AREA)
CN201480016186.8A 2013-03-15 2014-03-14 含卡巴拉汀的经皮给药系统 Pending CN105263488A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361799015P 2013-03-15 2013-03-15
US61/799,015 2013-03-15
PCT/US2014/027357 WO2014152454A1 (en) 2013-03-15 2014-03-14 Transdermal drug delivery system containing rivastigmine

Publications (1)

Publication Number Publication Date
CN105263488A true CN105263488A (zh) 2016-01-20

Family

ID=51528077

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480016186.8A Pending CN105263488A (zh) 2013-03-15 2014-03-14 含卡巴拉汀的经皮给药系统

Country Status (10)

Country Link
US (1) US20140271866A1 (https=)
EP (1) EP2968248A4 (https=)
JP (1) JP6391664B2 (https=)
KR (1) KR20160005024A (https=)
CN (1) CN105263488A (https=)
AU (1) AU2014239687B2 (https=)
CA (1) CA2906796A1 (https=)
HK (1) HK1220109A1 (https=)
TW (1) TWI635876B (https=)
WO (1) WO2014152454A1 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105693556A (zh) * 2016-03-01 2016-06-22 巴斯特医药科技（常州）有限公司 卡巴拉汀酒石酸盐的转化方法及其产物制成的贴片
CN108926549A (zh) * 2018-09-27 2018-12-04 安徽安科余良卿药业有限公司 卡巴拉汀凝胶贴膏及其制备方法
CN111093639A (zh) * 2017-09-05 2020-05-01 罗曼治疗系统股份公司 用于卡巴拉汀经皮给药的经皮治疗系统

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104523656A (zh) * 2014-11-20 2015-04-22 美吉斯制药（厦门）有限公司 一种卡巴拉汀缓释透皮贴剂及其制备方法
ES2769286T3 (es) 2016-12-20 2020-06-25 Lts Lohmann Therapie Systeme Ag Sistema terapéutico transdérmico que contiene asenapina
WO2018115010A1 (en) 2016-12-20 2018-06-28 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine and polysiloxane or polyisobutylene
ES2881783T3 (es) 2017-06-26 2021-11-30 Lts Lohmann Therapie Systeme Ag Sistema terapéutico transdérmico que contiene asenapina y polímero de acrílico y silicona
CA3101420A1 (en) 2018-06-20 2019-12-26 Lts Lohmann Therapie-Systeme Ag Transdermal therapeutic system containing asenapine
CN112533593A (zh) 2018-06-20 2021-03-19 罗曼治疗系统股份公司 含有阿塞那平的透皮治疗系统
KR102710072B1 (ko) * 2018-08-31 2024-09-24 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
TWI720366B (zh) 2018-11-16 2021-03-01 得生製藥股份有限公司 經皮吸收貼片
CN113616625B (zh) * 2021-08-26 2023-05-30 大连科翔科技开发有限公司 一种卡巴拉汀的长效透皮贴剂

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1354654A (zh) * 1999-04-22 2002-06-19 罗曼治疗系统股份公司 包括经中和的压力敏感性丙烯酸酯粘附剂的穿皮治疗系统
CN1450882A (zh) * 1999-11-04 2003-10-22 美国爱科赛尔制药有限公司 石杉碱经皮给药制剂
CN102159205A (zh) * 2008-06-25 2011-08-17 Fe3医学有限公司 用于经皮递送治疗有效量的铁的贴片和方法
DE102010026903A1 (de) * 2010-07-12 2012-01-12 Amw Gmbh Transdermales therapeutisches System mit Avocadoöl oder Palmöl als Hilfsstoff
CN102630160A (zh) * 2009-09-16 2012-08-08 株式会社三养社 透皮递送系统、其制备方法以及使用所述系统的透皮递送方法

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US5059426A (en) * 1989-03-22 1991-10-22 Cygnus Therapeutic Systems Skin permeation enhancer compositions, and methods and transdermal systems associated therewith
KR960703956A (ko) * 1993-07-08 1996-08-31 로버트 지. 반 슌넨베르그 아크릴릭-포화 고무 하이브리드 감압 접착제
US20020192243A1 (en) * 1999-12-16 2002-12-19 Tsung-Min Hsu Transdermal and topical administration of drugs for the treatment of Alzheimer's disease using basic enhancers
US6455066B1 (en) * 2000-03-10 2002-09-24 Epicept Corporation Intradermal-penetration agents for topical local anesthetic administration
US7638522B2 (en) * 2001-08-13 2009-12-29 Janssen Pharmaceutica N.V. Salt of 4-[[4-[[4-(2-cyanoethenyl)-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino] benzonitrile
KR20050045946A (ko) * 2002-06-25 2005-05-17 애크럭스 디디에스 피티와이 리미티드 비정질 약학적 조성물을 이용한 경피전달속도의 제어
US7516422B2 (en) * 2005-07-21 2009-04-07 International Business Machines Corporation Graphical display of hierarchical hardlinks to files in a file system
TWI389709B (zh) * 2005-12-01 2013-03-21 Novartis Ag 經皮治療系統
DE602006020063D1 (de) * 2005-12-07 2011-03-24 Univ Ramot Wirkstoffabgebende verbundkörper
US8440304B2 (en) * 2008-09-16 2013-05-14 Henkel Corporation Acrylic pressure sensitive adhesive formulation and articles comprising same
JP2012236773A (ja) * 2009-12-16 2012-12-06 Goto Takeshi 抗認知症薬物の経皮吸収製剤
NZ605352A (en) * 2010-06-30 2013-10-25 Nal Pharmaceuticals Ltd Process for producing glycosaminoglycans
KR101853082B1 (ko) * 2011-03-24 2018-04-27 테이코쿠 팔마 유에스에이, 인코포레이티드 활성제층 및 활성제 변환층을 포함하는 경피 조성물

Patent Citations (5)

* Cited by examiner, † Cited by third party
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CN1354654A (zh) * 1999-04-22 2002-06-19 罗曼治疗系统股份公司 包括经中和的压力敏感性丙烯酸酯粘附剂的穿皮治疗系统
CN1450882A (zh) * 1999-11-04 2003-10-22 美国爱科赛尔制药有限公司 石杉碱经皮给药制剂
CN102159205A (zh) * 2008-06-25 2011-08-17 Fe3医学有限公司 用于经皮递送治疗有效量的铁的贴片和方法
CN102630160A (zh) * 2009-09-16 2012-08-08 株式会社三养社 透皮递送系统、其制备方法以及使用所述系统的透皮递送方法
DE102010026903A1 (de) * 2010-07-12 2012-01-12 Amw Gmbh Transdermales therapeutisches System mit Avocadoöl oder Palmöl als Hilfsstoff

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
朱盛山: "《药物新剂型》", 31 August 2003, 化学工业出版社 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105693556A (zh) * 2016-03-01 2016-06-22 巴斯特医药科技（常州）有限公司 卡巴拉汀酒石酸盐的转化方法及其产物制成的贴片
CN111093639A (zh) * 2017-09-05 2020-05-01 罗曼治疗系统股份公司 用于卡巴拉汀经皮给药的经皮治疗系统
CN108926549A (zh) * 2018-09-27 2018-12-04 安徽安科余良卿药业有限公司 卡巴拉汀凝胶贴膏及其制备方法

Also Published As

Publication number Publication date
AU2014239687A1 (en) 2015-10-08
EP2968248A4 (en) 2016-08-31
HK1220109A1 (zh) 2017-04-28
TWI635876B (zh) 2018-09-21
EP2968248A1 (en) 2016-01-20
WO2014152454A1 (en) 2014-09-25
JP6391664B2 (ja) 2018-09-19
TW201505665A (zh) 2015-02-16
KR20160005024A (ko) 2016-01-13
AU2014239687B2 (en) 2018-04-05
US20140271866A1 (en) 2014-09-18
CA2906796A1 (en) 2014-09-25
JP2016522792A (ja) 2016-08-04

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C41 Transfer of patent application or patent right or utility model
TA01 Transfer of patent application right

Effective date of registration: 20160621

Address after: Hongkong Tongluowan China Gloucester Road No. 311 royal building room 2109

Applicant after: Royal Pharmaceutical Group

Address before: Hongkong Tongluowan China Gloucester Road No. 311 royal building room 2109

Applicant before: Nal Pharmaceuticals Ltd.

CB02 Change of applicant information

Address after: Hongkong Tongluowan China Gloucester Road No. 311 royal building room 2109

Applicant after: Aneng Tai Pharmaceutical Co. Ltd.

Address before: Hongkong Tongluowan China Gloucester Road No. 311 royal building room 2109

Applicant before: Royal Pharmaceutical Group

COR Change of bibliographic data
RJ01 Rejection of invention patent application after publication

Application publication date: 20160120

RJ01 Rejection of invention patent application after publication