CN1052510C - 白细胞介素－10的哺乳动物受体 - Google Patents

白细胞介素－10的哺乳动物受体 Download PDF

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Publication number
CN1052510C
CN1052510C CN93121682A CN93121682A CN1052510C CN 1052510 C CN1052510 C CN 1052510C CN 93121682 A CN93121682 A CN 93121682A CN 93121682 A CN93121682 A CN 93121682A CN 1052510 C CN1052510 C CN 1052510C
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CN
China
Prior art keywords
leu
fragment
ser
nucleic acid
protein
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN93121682A
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English (en)
Chinese (zh)
Other versions
CN1090326A (zh
Inventor
K·W·穆尔
刘�英
何淑榆
徐迪惠
J·C·陈
周传初
J·F·巴桑
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Merck Sharp and Dohme Corp
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Schering Corp
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5428—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CN93121682A 1992-12-10 1993-12-10 白细胞介素－10的哺乳动物受体 Expired - Fee Related CN1052510C (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US98979292A 1992-12-10 1992-12-10
US989,792 1992-12-10
US1106693A 1993-01-29 1993-01-29
US011,066 1993-01-29
US110,683 1993-08-23
US08/110,683 US5789192A (en) 1992-12-10 1993-08-23 Mammalian receptors for interleukin-10 (IL-10)

Publications (2)

Publication Number Publication Date
CN1090326A CN1090326A (zh) 1994-08-03
CN1052510C true CN1052510C (zh) 2000-05-17

Family

ID=27359359

Family Applications (1)

Application Number Title Priority Date Filing Date
CN93121682A Expired - Fee Related CN1052510C (zh) 1992-12-10 1993-12-10 白细胞介素－10的哺乳动物受体

Country Status (15)

Country Link
US (4) US5789192A (xx)
EP (1) EP0673420B1 (xx)
JP (1) JP3135576B2 (xx)
CN (1) CN1052510C (xx)
AT (1) ATE177147T1 (xx)
AU (1) AU5734094A (xx)
CA (1) CA2151141C (xx)
DE (1) DE69323765T2 (xx)
DK (1) DK0673420T3 (xx)
ES (1) ES2129622T3 (xx)
GR (1) GR3030038T3 (xx)
HK (1) HK1008830A1 (xx)
IL (1) IL107951A (xx)
MY (1) MY109045A (xx)
WO (1) WO1994013801A1 (xx)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994022914A1 (en) * 1993-04-06 1994-10-13 Fred Hutchinson Cancer Research Center Chimeric cytokine receptors in lymphocytes
US6849461B2 (en) * 1994-06-17 2005-02-01 Evotec Oai Ag Method and device for the selective withdrawal of components from complex mixtures
US5885574A (en) * 1994-07-26 1999-03-23 Amgen Inc. Antibodies which activate an erythropoietin receptor
DE69841514D1 (de) 1997-05-07 2010-04-01 Schering Corp Menschliche Toll-Like-Rezeptorproteine, zugehörige Reagenzien und Verfahren
US5965704A (en) * 1997-08-05 1999-10-12 Zymogenetics, Inc. Class two cytokine receptor-11
WO2000039161A1 (en) * 1998-12-31 2000-07-06 Millennium Pharmaceuticals, Inc. Class ii cytokine receptor-like proteins and nucleic acids encoding them
US6939545B2 (en) * 1999-04-28 2005-09-06 Genetics Institute, Llc Composition and method for treating inflammatory disorders
EP1950299A1 (en) 1999-06-01 2008-07-30 Schering Corporation Mammalian receptor proteins; related reagents and methods
WO2001008717A1 (en) * 1999-08-03 2001-02-08 Smith & Nephew, Inc. Controlled release implantable devices
US7122632B2 (en) * 1999-12-23 2006-10-17 Zymogenetics, Inc. Soluble Interleukin-20 receptor
US6610286B2 (en) 1999-12-23 2003-08-26 Zymogenetics, Inc. Method for treating inflammation using soluble receptors to interleukin-20
WO2001064713A2 (en) * 2000-03-01 2001-09-07 Christoph Gasche Mammalian interleukin-10 (il-10) receptor variants
CN1441677A (zh) * 2000-03-31 2003-09-10 Idec药物公司 抗细胞因子抗体或拮抗剂与抗－cd20在b细胞淋巴瘤治疗中的联合应用
NZ522146A (en) 2000-05-10 2004-10-29 Schering Corp Mammalian receptor-like proteins, designated DNAX cytokine receptor subunits (DCRS), in particular DCRS5
ES2381650T3 (es) * 2000-08-08 2012-05-30 Zymogenetics, Inc. Receptores de citoquinas Zcytor11 solubles
CA2422033A1 (en) * 2000-09-15 2002-03-21 Zymogenetics, Inc. Method for treating inflammation
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
US7638604B2 (en) * 2001-02-23 2009-12-29 Genetics Institute, Llc Monoclonal antibodies against interleukin-22
CA2467723C (en) * 2001-12-17 2011-09-27 Zymogenetics, Inc. Method for treating cervical cancer
US20060063156A1 (en) * 2002-12-06 2006-03-23 Willman Cheryl L Outcome prediction and risk classification in childhood leukemia
MXPA05010134A (es) * 2003-03-24 2005-11-16 Zymogenetics Inc Anticuerpos anti-il-20, metodos y moleculas de enlace que se usan en la inflamacion.
JP4635255B2 (ja) * 2003-09-02 2011-02-23 独立行政法人産業技術総合研究所 抗体医薬
US7393684B2 (en) * 2003-11-21 2008-07-01 Zymogenetics, Inc. Immunoconjugates of anti-IL-20 antibodies and hybridoma cell lines expressing anti-IL-20 antibodies
US20050132599A1 (en) * 2003-12-18 2005-06-23 Lg Electronics Inc. Drying method of washing machine and apparatus thereof
DE602005022475D1 (de) 2004-10-22 2010-09-02 Zymogenetics Inc Anti-il-22ra-antikörper und bindungspartner und verfahren zur anwendung bei entzündungen
US20060177883A1 (en) 2005-02-08 2006-08-10 Saladax Biomedical Inc. 5-Fluoro-uracil immunoassay
EP1712241A1 (en) * 2005-04-15 2006-10-18 Centre National De La Recherche Scientifique (Cnrs) Composition for treating cancer adapted for intra-tumoral administration and uses thereof
TW200744634A (en) * 2006-02-21 2007-12-16 Wyeth Corp Methods of using antibodies against human IL-22
TWI417301B (zh) 2006-02-21 2013-12-01 Wyeth Corp 對抗人類介白素-２２（ｉｌ-２２）之抗體及其用途
RS61082B1 (sr) 2010-02-26 2020-12-31 Novo Nordisk As Stabilno antitelo koje sadrži kompozicije
RU2012153786A (ru) 2010-05-28 2014-07-10 Ново Нордиск А/С Стабильные многодозовые композиции, содержащие антитело и консервант
CA2979973A1 (en) * 2015-04-29 2016-11-03 Mediolanum Farmaceutici S.P.A. A soluble chimeric interleukin-10 receptor and therapeutic use thereof
CN113125730B (zh) * 2019-12-31 2023-07-07 科美博阳诊断技术(上海)有限公司 一种白介素6的均相检测试剂盒及其应用

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIEMCES OF USA WOL.9 1993.1.1 ARECEPTOR FOR INTELEUKIN 10 IS RELATED TO INTERFERON RECEPTORS HO AS;LIU Y;KHAN TA HSU DH BAXAN JE M *

Also Published As

Publication number Publication date
HK1008830A1 (en) 1999-05-21
GR3030038T3 (en) 1999-07-30
AU5734094A (en) 1994-07-04
CA2151141A1 (en) 1994-06-23
US5985828A (en) 1999-11-16
CA2151141C (en) 2001-07-17
US5789192A (en) 1998-08-04
DK0673420T3 (da) 1999-10-04
EP0673420B1 (en) 1999-03-03
IL107951A (en) 2003-12-10
DE69323765T2 (de) 1999-07-22
IL107951A0 (en) 1994-04-12
US5863796A (en) 1999-01-26
DE69323765D1 (de) 1999-04-08
US6423500B1 (en) 2002-07-23
ATE177147T1 (de) 1999-03-15
CN1090326A (zh) 1994-08-03
JP3135576B2 (ja) 2001-02-19
MY109045A (en) 1996-11-30
EP0673420A1 (en) 1995-09-27
JPH07509613A (ja) 1995-10-26
WO1994013801A1 (en) 1994-06-23
ES2129622T3 (es) 1999-06-16

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