CN105232746A - Traditional Chinese medicine composition and traditional Chinese medicine preparation for treating thoracic wall contusion and rib fracture and preparation method of traditional Chinese medicine preparation - Google Patents
Traditional Chinese medicine composition and traditional Chinese medicine preparation for treating thoracic wall contusion and rib fracture and preparation method of traditional Chinese medicine preparation Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition and a traditional Chinese medicine preparation for treating thoracic wall contusion and rib fracture and a preparation method of the traditional Chinese medicine preparation and belongs to the technical field of traditional Chinese medicine compositions. The traditional Chinese medicine composition comprises, by weight, 3-15 parts of Chinese thorowax root, 6-12 parts of semen persicae, 3-9 parts of safflower, 6-15 parts of radix angelicae sinensis, 3-12 parts of Szechuan lovage rhizome, 6-12 parts of red peony root, 6-15 parts of twotooth achyranthes root, 3-15 parts of Danshen root, 6-9 parts of fructus aurantii, 3-10 parts of platycodon root, 6-15 parts of rhizoma corydalis, 2-12 parts of costustoot, 3-6 parts of liquorice and 6-15 parts of dried rehmannia root. The traditional Chinese medicine composition has the advantages that the traditional Chinese medicine composition is capable of promoting blood circulation to remove blood stasis while promoting qi circulation to disperse depressed emotion, eliminating phlegm while nourishing blood to avoid blood consumption during blood circulation promoting and impairment of yin during qi circulation promoting, and elevating yang while rushing down to descend to enable qi and blood to be harmonious; the traditional Chinese medicine composition is quite low in cost and exact in treatment effect when being used for treating thoracic wall contusion and rib fracture gall symptoms.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicine, be specifically related to a kind of Chinese medicine composition, Chinese medicine preparation and preparation method thereof that are used for the treatment of thoracic wall contusion, fracture of rib.
Background technology
Thoracic wall is dampened, fracture of rib belongs to the common emergency case of traditional Chinese medical science Orthopeadic Surgery.Because breast side of body portion suffers violence more than thoracic wall contusion, cause soft tissue injury, QI-blood circulation is smooth, and the stagnation of QI is had a pain.Traditional Chinese medical science medical science thinks that breast is the dividing line of lung, and the arteries and veins of Liver Channel is from bottom to top to coercing rib, and the arteries and veins of gallbladder meridian from top to bottom follows costa sternales, lung governing qi, blood stored in the liver, QI and blood is gone together in the heart, and gas passes through thoracic cavity, qi-movement disturbance, impaired depurative descending of lung QI, the stagnation of QI is lost smooth, and blood stasis seldom follows row, Zhu Yang is bullied in the heart, due to qi depression to blood stasis, the defeated cloth of hypofunction of YANG QI in chest bringing about the spread of body fluid is hindered, and water is wet to stop gathering not change to form expectorant.
Fracture of rib is the most common in thoracic trauma, is more common in the violences such as tumbling down, shock, vehicle accident and directly acts on rib and cause, and especially senile osteoporosis easily occurs, existing malignant metastatic tumor of bone person easily pathologisch Bruch occurs.Chinese medicine thinks that rib is easily damaged, and occurs that thoracic wall swells and ache after wound, is that passages through which vital energy circulates is damaged by the fracture injury of tendon and muscle, outside blood oozing from the body openings or subcuta neous tissue arteries and veins, under the stasis of blood amasss rib, caused by retardance mechanism of qi." impairment of QI is pain then ", " shape wound then swells ".Be lungs in costa sternales, costa sternales is badly wounded, must affect the respiratory function of lungs.These are many because of qi and blood stagnation, make deficient airway, impairment of purifying function of the lung, caused by gas superinverse, gas have some setbacks.If under the long-pending side of body of the stasis of blood, also can cause liver mistake bar and reach, anti-insult lung gold, sends out as breathing with cough.After thoracic injury, long-pending stasis of blood heat-dissipating, damage lung qi after adding wound, wind, expectorant, stasis of blood three stop up stagnant fire-transformation, also can send out as cough and choke is more than.After wound, six climate exopathogens exopathogen is taken advantage of a weak point in opponent's defence and people and cause lungs functional disorder, occurs breathing with cough and dyspnea.
At present, the Therapeutic Principle of thoracic wall contusion, fracture of rib is based on effective control pain, pulmonary physiotherapy and early ambulant.Surgery of Chinese medicine while the reduction of the fracture, the treatment such as fixing, early stage (in injured 10d), injury costa sternales swells and ache, local ecchymosis, tenderness, deeply breathe and cough, sneeze time increase the weight of, severe one dare not be spoken up, dyspnea.Tongue is dim red, or has ecchymosis, white and thin fur, stringy pulse or number.Control suitable blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain.Useful Fuyuan Huoxue Tang plus-minus, makes the stasis of blood go new life, the capable ruton of gas, then hypochondriac pain is from stopping.Mid-term (after injured 10d) place's pain relief, but when deeply breathing and cough still comparatively bitterly, tenderness, tongue is dim red, white and thin fur, stringy pulse.Control suitable blood-activating and qi-promoting, dispersing the depressed liver-QI for alleviating pain.Side's bupleurum powder for relieving liver-qi is added and subtracted.Later stage (wound after 6 ~ 8 weeks), general fracture healed, but can still leave over flank and have a dull ache, and chest tightness is smooth, still has and takes out bitterly, light red tongue, white and thin fur, thready pulse when cough is coughed up phlegm.The liver and the kidney tonifying, invigorating QI and blood, is aided with promoting flow of QI and blood.Blood-activating bone-resetting Tonga subtracts.Mainly with blood circulation promoting and blood stasis dispelling, to be aided with nutrition be main, but therapeutic effect is limited.Chinese medicine is used for the treatment of that thoracic wall is dampened, the formula of fracture of rib is less, Chinese medicine greatly mainly with Radix Paeoniae, Rhizoma Chuanxiong, Flos Chrysanthemi etc. except wind medicine is main formula.
In prior art, CN1623588A " a kind of treat fracture and the Chinese medicine composition of soft tissue injury " discloses the Chinese medicine composition comprising following component: Lignum Sappan 7-30, Flos Carthami 3-12, Semen Persicae 3-12, Radix Angelicae Sinensis 4-18, Rhizoma Chuanxiong 3-12, Radix Paeoniae Rubra 5-20, Radix Rehmanniae 5-20, Olibanum 6-25, Myrrha 6-25, Cortex Eucommiae 6-25, Rhizoma Sparganii 5-20, Rhizoma Curcumae 5-20, Ramulus Cinnamomi 4-18, Radix Achyranthis Bidentatae 4-18, Rhizoma Alismatis 5-20, Cortex Moutan 3-12, and this Chinese medicine composition has relaxing muscles and tendons to promote blood circulation and battalion's dredging collateral, dissipating blood stasis and to dispel effect of pain.But be used for the treatment of thoracic wall contusion, fracture of rib less effective.
Summary of the invention
First object of the present invention is to provide a kind of Chinese medicine composition being used for the treatment of thoracic wall contusion, fracture of rib, this Chinese medicine composition, and cost is lower, and treatment thoracic wall is dampened, fracture of rib swells and ache symptom determined curative effect.
Second object of the present invention is to provide a kind of Chinese medicine preparation being used for the treatment of thoracic wall contusion, fracture of rib.
3rd object of the present invention is to provide a kind of above-mentioned being used for the treatment of, and thoracic wall is dampened, the preparation method of the Chinese medicine preparation of fracture of rib.
For realizing above object, the technical solution used in the present invention is:
Be used for the treatment of a Chinese medicine composition for thoracic wall contusion, fracture of rib, be made up of the component of following parts by weight: Radix Bupleuri 3 ~ 15 parts, 6 ~ 12 parts, Semen Persicae, 3 ~ 9 parts, Flos Carthami, Radix Angelicae Sinensis 6 ~ 15 parts, Rhizoma Chuanxiong 3 ~ 12 parts, Radix Paeoniae Rubra 6 ~ 12 parts, Radix Achyranthis Bidentatae 6 ~ 15 parts, Radix Salviae Miltiorrhizae 3 ~ 15 parts, Fructus Aurantii 6 ~ 9 parts, Radix Platycodonis 3 ~ 10 parts, Rhizoma Corydalis 6 ~ 15 parts, the Radix Aucklandiae 2 ~ 12 parts, 3 ~ 6 parts, Radix Glycyrrhizae, 6 ~ 15 parts, the Radix Rehmanniae.
Preferably, be used for the treatment of a Chinese medicine composition for thoracic wall contusion, fracture of rib, be made up of the component of following parts by weight: Radix Bupleuri 15 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 12 parts, Radix Paeoniae Rubra 12 parts, Radix Achyranthis Bidentatae 12 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Aurantii 9 parts, Radix Platycodonis 10 parts, Rhizoma Corydalis 15 parts, the Radix Aucklandiae 12 parts, 6 parts, Radix Glycyrrhizae, 12 parts, the Radix Rehmanniae.
In Chinese medicine composition of the present invention, the property of medicine drug effect of each tcm components is as follows:
Radix Bupleuri: be the root of Umbelliferae Bupleunim. L Radix Bupleuri or Radix Bupeuri Scorzonerfolii.; Containing volatile oil as o-methoxyphenol, heptalactone, caprylolactone, decalactone, eugenol, undecalactone etc., also contain saponins as saikoside, acetyl saikoside, flavonoid is as the effective ingredient such as rutin, Quercetin.Bitter, pungent, be slightly cold, return liver, gallbladder meridian; Effect is brought down a fever for inducing sweat, dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy; Cure mainly fever caused by exogenous pathogens, alternate attack of chill and fever, malaria, hypochondriac pain due to stagnation of liverQI mammary swelling, headache dizziness, menoxenia, proctoptosis, the uterus of collapse of QI hang, gastroptosis.Modern pharmacology research shows, Radix Bupleuri has antiinflammatory, antipyretic, calm, analgesia, antitussive, protects the liver, protects the effects such as stomach, blood fat reducing, anti-bacteria and anti-virus, antitumor, promotion metabolism.
Semen Persicae: be the seed of Rosaceae peach family plant seed Fructus Persicae or Prunus davidiana; Containing effective ingredient such as amygdaloside, Virginia prune glucoside, sterols, organic acid, protein.Property is bitter, sweet, flat, GUIXIN, liver, large intestine channel.Effect is blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation; Cure mainly dysmenorrhea, amenorrhea due to stagnation of blood, the stasis of blood in puerperal stagnant stomachache ， WEIJIA is lumpd, and traumatic injury, congestion swells and ache, lung abscess, acute appendicitis, dryness of the intestine constipation.Modern pharmacology research shows, Semen Persicae has the effect such as promotion circulatory function, anticoagulation and antithrombotic, antiinflammatory, eliminating phlegm and stopping cough, antitumor.
Flos Carthami: be the flower of Compositae Flos Carthami platymiscium Flos Carthami; Containing flavone compounds such as saffloside, front saffloside, Carthamus yellow, the bright glycosides of Flos Carthami, also containing effective ingredient such as chlorogenic acid, caffeic acid, verbenone and 16 seed amino acids.Property is pungent, warm, GUIXIN, Liver Channel; Effect is promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; Cure mainly blood stasis amenorrhea, dysmenorrhea, postpartum stagnation is suffered from abdominal pain, and obstruction of qi in the chest and cardialgia ， WEIJIA is gathered, traumatic injury, arthralgia, apoplectic hemiplegia, macule.Modern pharmacology research shows, Flos Carthami has the effect strengthening systema cariovasculare functional, anticoagulation, blood fat reducing, enhancing hypoxia endurance, immunocompetence and antiinflammatory.
Radix Angelicae Sinensis: be the afterbody of Chinese medicine angelica; Surface yellowish-brown is to sepia, and tool indulges wrinkle and hole skin of growing crosswise, tool ring grain.Have effect of blood circulation promoting and blood stasis dispelling, the obstructed and congestion for the treatment of amenorrhea stagnates the disease swollen and ache.
Rhizoma Chuanxiong: be the rhizome of Umbelliferae Ligustrum plant Rhizoma Chuanxiong; Containing multiple lactones such as ligustrazine, loline, perlolyrine, ligustilide, Rhizoma Chuanxiong naphthalene furan lactones, also containing the plurality of active ingredients such as phenolic acids, volatile oil.Property is pungent, warm, returns liver, gallbladder, pericardium channel; Effect is blood circulation promoting and blood stasis dispelling, activating QI to alleviate the depression, wind-expelling pain-stopping; Cure mainly menoxenia, amenorrhea dysmenorrhea, the stasis of blood in puerperal stagnant stomachache ， WEIJIA lump, pain in chest and hypochondrium, has a headache dizzy, anemofrigid-damp arthralgia, traumatic injury, ulcer sores.Modern pharmacology research shows, Rhizoma Chuanxiong has enhancing systema cariovasculare functional (as blood vessel dilating, suppress hypertension, to resist myocardial ischemia and Reperfusion injury injures protective effect etc. to cerebral ischemia), strengthens hematological function, strengthens the effect such as urinary system and function of immune system, antitumor, anti-radiation.
Radix Paeoniae Rubra: be the root of Paeoniaceae Paeonia plant peony, CHUANSHAO medicine; Containing monoterpenes as peoniflorin, organic acid as benzoic acid, gallic acid, the effective ingredient such as catechin, sitosterol.Property bitter, be slightly cold; Return liver, spleen channel.Effect is clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling; Cure mainly maculae caused by violent heat pathogen, hematemesis and epistaxis, discharging fresh blood stool, conjunctival congestion and swelling pain, carbuncle skin infection, amenorrhea, dysmenorrhea, metrorrhagia and leukorrhagia stranguria with turbid discharge, the stagnant hypochondriac pain of the stasis of blood, hernia abdominal mass is gathered, injury from falling down.Modern pharmacology research shows, the effects such as Radix Paeoniae Rubra has antithrombus formation and antiplatelet aggregation, arteriosclerosis, promotion systema cariovasculare functional, antitumor, protect the liver.
Radix Achyranthis Bidentatae: be the root of Amaranthaceae Achyranthes plant Radix Achyranthis Bidentatae; Containing triterpene saponin as radix achyranthis bidentatae saponin, ginsenoside, Rhizoma Panacis Japonici saponin etc., also containing plurality of active ingredients such as polysaccharide, ketosteroid, aminoacid, protein.Property bitter, acid, flat, return liver, kidney channel; Effect is invigorating the liver and kidney, bone and muscle strengthening, promoting blood circulation to restore menstrual flow, draws blood (fire) descending, inducing diuresis for treating stranguria syndrome; Cure mainly soreness of waist and knee joint, flaccidity and weakness of the lower limbs, amenorrhea due to stagnation of blood, dysmenorrhea, puerperal abdominal pain due to blood stasis ， WEIJIA, retention of placenta, pyretic stranguria, stranguria with blood, traumatic injury, carbuncle malignant boil, laryngopharynx swelling and pain.Modern pharmacology research shows, Radix Achyranthis Bidentatae has antalgic and inflammation relieving, improves cardiovascular and Respiratory ft tive resistance, antifertility, blood sugar lowering, raising function of immune system, slow down aging, antineoplastic action.In Chinese medicine composition of the present invention, described Radix Achyranthis Bidentatae is Radix Cyathulae.
Radix Salviae Miltiorrhizae: be the root of Lamiaceae Salvia platymiscium Radix Salviae Miltiorrhizae; Containing quinoness such as TANSHINONES, Radix Salviae Miltiorrhizae ketolide, cryptotanshinone, iso tanshinones, also contain water-soluble phenolic compounds as the effective ingredient such as salvianolic acid, protocatechualdehyde.Property bitter, be slightly cold, GUIXIN, Bao Xin, Liver Channel; Effect is blood circulation promoting and blood stasis dispelling, menstruction regulating and pain relieving, and relieving restlessness is calmed the nerves, removing heat from blood eliminating carbuncle; Cure mainly menoxenia, dysmenorrhea, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, trusted subordinate's pain, WEIJIA is gathered, and pyretic arthralgia swells and ache, traumatic injury, and heat enters nutrient blood, dysphoria, vexed insomnia, carbuncle pyogenic infections from tumour or sore.Modern pharmacology research shows, Radix Salviae Miltiorrhizae has enhancing cardio-cerebrovascular function, blood fat reducing and atherosclerosis, anticoagulant and antithrombotic, anoxia enduring, enhancing function of immune system, antiinflammatory and antiallergic, hepatoprotective, anti-gastric-ulcer, improves the effect such as renal function and antioxidation.
Fructus Aurantii: be Rutaceae citrus plant Citrus aurantium Linn. and cultivation product green fruit thereof; Containing flavonoid as effective ingredient such as Hesperidin, alkaloid, limonins; Property bitter, sour, temperature, returns lung, spleen, stomach, large intestine channel.Effect is the chest stuffiness relieving of regulating the flow of vital energy, the stagnant removing food stagnancy of row; Cure mainly the acid of chest and diaphragm band, distending pain over the hypochondrium, accumulation of food in the stomach and intes tine due to indigestion, distension and fullness in the abdomen, heavy after dysentery, uterine prolapse.Modern pharmacology research proves that Fructus Aurantii has and strengthens the effect such as systema cariovasculare functional, promotion gastrointestinal.
Radix Platycodonis: be the root of campanulaceae Platycodon grandiflouorum Platycodon grandiflouorum; Containing effective ingredient such as platycodin, sapogenin, sterols.Bitter in the mouth, property is put down, and returns lung meridian.There is out lung qi dispersing gas, the effect of evacuation of pus of eliminating the phlegm.The diseases such as be used for the treatment of exogenous cough, laryngopharynx swelling and pain, lung abscess is spat, fullness in the chest and hypochondriac pain, dysentery stomachache." pearl sac " is recorded: " passing through with Radix Glycyrrhizae, is drugs of guiding other drugs to act on upper JIAO ".Radix Platycodonis has many-sided pharmacological action, is wherein a most important ring to the regulating and controlling effect of macrophage, is one of the mechanism of action of Radix Platycodonis antiinflammatory, antitumor, resisting pathogenic microbes.
Rhizoma Corydalis: be the tuber of Papaveraceae Genus Corydalis Rhizoma Corydalis; Containing alkaloid as effective ingredient such as corydaline, protopine, Tetrahydrocoptisines.Property acrid, bitter, warm, returns liver, stomach, the heart, lung, spleen channel.Effect is for invigorating blood circulation, and dissipating blood stasis, regulates the flow of vital energy, pain relieving; Cure mainly all pains of trusted subordinate's waist knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury.Modern pharmacology research proves, Rhizoma Corydalis has pain relieving analgesia, hypnosis, calmness, stable, antitumor, facilitating digestion systemic-function, promotes the effects such as systema cariovasculare functional.
The Radix Aucklandiae: different name Radix Aucklandiae (Radix Vladimiriae) is the root of the Compositae Saussurea lappa Clarke platymiscium Radix Aucklandiae; Root oil is containing effective ingredient such as lactone compound, volatile ingredient and several amino acids; Property pungent, bitter, temperature, return spleen, stomach, liver, lung meridian.Effect is promoting the circulation of QI to relieve pain, intestinal stasis relieving in tune; Cure mainly fullness and distention in the chest and hypochondrium, abdominal distention, vomiting is had loose bowels, heavy after dysentery.Modern pharmacology research proves, the Radix Aucklandiae has effects such as promoting gastrointestinal tract, blood pressure lowering, antiinflammatory, analgesia, blood sugar lowering.
Radix Glycyrrhizae: be the root and rhizome of pulse family glycyrrhiza genus Radix Glycyrrhizae, Glycyrrhiza glabra L., Glycyrrhiza inflata Bat.; Containing plurality of active ingredients such as triterpene saponin, flavone compound, coumarin kind compound, alkaloids and polysaccharide; Sweet, flat, return spleen, stomach, the heart, lung meridian.Effect is and middle emergency, lung moistening, removing toxic substances, coordinating the actions of various ingredients in a prescription; Cure mainly weakness of the spleen and stomach, asthenia lack of appetite, stomachache loose stool, the anxious pain of extremity contraction, cardiopalmus, dirty dry, consumptive lung disease is coughed, laryngopharynx swelling and pain, carbuncle pyogenic infections from tumour or sore, infantile carbuncle and medicine, alimentary toxicosis.Modern pharmacology research proves that Radix Glycyrrhizae has antimicrobial, improves systema cariovasculare functional, facilitating digestion, protects the liver, antiinflammatory, ease pain, eliminate the phlegm, improve the effects such as function of immune system, antitumor, mutation, removing toxic substances, antioxidation.
The Radix Rehmanniae: be the tuber of scrophulariaceae rehmannia glutinosa plant; Sweet, cold, GUIXIN, liver, kidney channel.Containing effective ingredient such as sitosterol and mannitol, rehmanin, alkaloid, fatty acid, glucose and vitamin A.There is clearing away heat and cooling blood, effect that tonifying YIN promotes the production of body fluid, to join the army blood for warm febrile disease, high fever coma, xerostomia crimson tongue.
In Chinese medicine composition of the present invention, Semen Persicae, removing blood stasis, moisturizes laxation; Flos Carthami, promoting blood circulation to restore menstrual flow, stasis-dispelling and pain-killing; Radix Angelicae Sinensis, promoting blood circulation and stopping pain, loosening bowel to relieve constipation, tonifying blood and regulating menstruation; Rhizoma Chuanxiong, blood-activating and qi-promoting, wind-expelling pain-stopping; Radix Paeoniae Rubra, promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, liver heat removing and eyesight improving, eliminating carbuncle are loose swollen; Radix Achyranthis Bidentatae, blood circulation promoting and blood stasis dispelling, bone and muscle strengthening, sharp joint, conducting blood to flow downwards, inducing diuresis for treating stranguria syndrome; Radix Salviae Miltiorrhizae, blood circulation promoting and blood stasis dispelling, promoting blood circulation and detumescence, nourishing blood to tranquillize the mind.Radix Platycodonis, lung qi dispersing eliminates the phlegm, relieving sore throat and pain, removing pus and relieving carbuncle; Radix Glycyrrhizae, invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain.Rhizoma Corydalis, blood-activating and qi-promoting pain relieving; Radix Bupleuri, expelling pathogenic factors from the exterior expels the heat-evil, dispersing the stagnated live-QI to relieve the stagnation of QI, ascending up spleen-Qi and Yang, for bringing down a fever; The Radix Aucklandiae, promoting the circulation of QI to relieve pain, invigorating the stomach and promoting digestion.Fructus Aurantii, dispelling the stagnated QI removing food stagnancy, therapeutic method to keep the adverse QI flowing downwards relieving constipation; The Radix Rehmanniae, clearing away heat and cooling blood, cooling blood for hemostasis, YIN nourishing and the production of body fluid promoting.All medicines share, and invigorate blood circulation with circulation of qi promoting phase 5, both the promoting the circulation of blood point stasis of blood was stagnant, separate edema caused by disorder of QI pent-up again; Eliminate the phlegm and nourish blood with executing, then invigorate blood circulation and without the worry of hematozemia, circulation of qi promoting without the fraud of impairment of YIN, lifting takes into account, and can rise to reach sun clearly, help again that to fall diarrhea capable, make QI and blood and tune.
The Chinese medicine composition being used for the treatment of thoracic wall contusion, fracture of rib of the present invention, adopt Radix Bupleuri, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Fructus Aurantii, Radix Platycodonis, Rhizoma Corydalis, the Radix Aucklandiae, Radix Glycyrrhizae, this 14 taste Chinese medicine of the Radix Rehmanniae composite, formula is reasonable, the Semen Persicae used in formula, Flos Carthami are monarch, Radix Paeoniae Rubra, Rhizoma Chuanxiong help monarch, Radix Achyranthis Bidentatae is minister, improve thoracic wall contusion, fracture of rib swells and ache symptom, compatible with Radix Platycodonis, Fructus Aurantii, Radix Bupleuri composition, regulating qi-flowing for activating stagnancy, dispersing the stagnated live-QI to relieve the stagnation of QI, plays the object of comprehensively regulating, treating both the principal and secondary aspects of a disease; The raw material of Chinese medicine wide material sources used in formula, with low cost, be used for the treatment of that thoracic wall is dampened, fracture of rib determined curative effect.
Be used for the treatment of a Chinese medicine preparation for thoracic wall contusion, fracture of rib, the raw material primarily of following parts by weight is made: Radix Bupleuri 3 ~ 15 parts, 6 ~ 12 parts, Semen Persicae, 3 ~ 9 parts, Flos Carthami, Radix Angelicae Sinensis 6 ~ 15 parts, Rhizoma Chuanxiong 3 ~ 12 parts, Radix Paeoniae Rubra 6 ~ 12 parts, Radix Achyranthis Bidentatae 6 ~ 15 parts, Radix Salviae Miltiorrhizae 3 ~ 15 parts, Fructus Aurantii 6 ~ 9 parts, Radix Platycodonis 3 ~ 10 parts, Rhizoma Corydalis 6 ~ 15 parts, the Radix Aucklandiae 2 ~ 12 parts, 3 ~ 6 parts, Radix Glycyrrhizae, 6 ~ 15 parts, the Radix Rehmanniae.
Preferably, be used for the treatment of a Chinese medicine preparation for thoracic wall contusion, fracture of rib, the raw material primarily of following parts by weight is made: Radix Bupleuri 15 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 12 parts, Radix Paeoniae Rubra 12 parts, Radix Achyranthis Bidentatae 12 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Aurantii 9 parts, Radix Platycodonis 10 parts, Rhizoma Corydalis 15 parts, the Radix Aucklandiae 12 parts, 6 parts, Radix Glycyrrhizae, 12 parts, the Radix Rehmanniae.
Described Chinese medicine preparation is powder, capsule, decoction or pill.The dosage form of described Chinese medicine preparation is powder, capsule, decoction or the pill made according to Chinese Pharmacopoeia 2010 editions requirements; Be preferably decoction.
Above-mentioned be used for the treatment of that thoracic wall is dampened, a preparation method for the Chinese medicine preparation of fracture of rib, comprise and measure raw material by formula, decoct with water for twice, collecting decoction, obtain decoction.
In above-mentioned preparation method, crude drug is placed in container, adds water to the water surface and exceed powder 3 ~ 5cm, after first intense fire boils, change slow fire, after boiling 20min, cross leaching decocting liquid; Add water again and carry out second time decoction (concrete operations are the same), merge twice decocting liquid, obtain decoction.
When described decoction is taken every day potion, every agent 450 ~ 550ml, under point 2 ~ 3 taking medicine after meales, 10th ~ 15 is a course for the treatment of.
Above-mentioned be used for the treatment of that thoracic wall is dampened, a preparation method for the Chinese medicine preparation of fracture of rib, comprise and measure raw material by formula, be crushed to 100 ~ 150 order fine powders, obtained powder or encapsulated capsule.
Above-mentioned be used for the treatment of that thoracic wall is dampened, a preparation method for the Chinese medicine preparation of fracture of rib, comprise the following steps:
1) measure raw material by formula, to pulverize and after sieving, sterilizing, obtains powder;
2) be the ratio of 100:30 according to the mass ratio of powder and middle honey, after being mixed with middle honey by powder, be heated to 65 ~ 75 DEG C and mix homogeneously with boiled water, make pellet after concise 3 times, rear drying, obtains honeyed pill.
Step 1) in, described in sieve and referred to 100 ~ 150 mesh sieves.
Step 1) in, described sterilizing is at 100 DEG C of sterilizing 30min.
Step 2) in, the temperature of described drying is 55 ~ 65 DEG C.
Described refine refers to the ball core (molding) first making a part of medicated powder be bonded into 0.5 ~ 1.0mm size for 3 times, again gained ball core is put into medicated powder shake to strengthen and generally make ball (molding), finally middle ball is made finished product size and make the surface compact of pill, bright and clean, color and luster consistent (capping).
The Chinese medicine preparation being used for the treatment of thoracic wall contusion, fracture of rib of the present invention, make primarily of Radix Bupleuri, Semen Persicae, Flos Carthami, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Rubra, Radix Achyranthis Bidentatae, Radix Salviae Miltiorrhizae, Fructus Aurantii, Radix Platycodonis, Rhizoma Corydalis, the Radix Aucklandiae, Radix Glycyrrhizae, this 14 taste Chinese medicine of the Radix Rehmanniae, can be powder, capsule, decoction or pill, be used for the treatment of thoracic wall contusion, fracture of rib is evident in efficacy.Wherein, decoction decocting is taken, easy to operate; Powder and capsule make simple, and cost is low, convenient storage and transport; Pill is honeyed pill, and when patient takes, compliance is better, and technique is simple, and cost is low, is applicable to large-scale industrial production.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further illustrated.
Embodiment 1
The Chinese medicine composition being used for the treatment of thoracic wall contusion, fracture of rib of the present embodiment, is made up of the component of following weight: Radix Bupleuri 15g, Semen Persicae 12g, Flos Carthami 9g, Radix Angelicae Sinensis 9g, Rhizoma Chuanxiong 12g, Radix Paeoniae Rubra 12g, Radix Achyranthis Bidentatae 12g, Radix Salviae Miltiorrhizae 12g, Fructus Aurantii 9g, Radix Platycodonis 10g, Rhizoma Corydalis 15g, Radix Aucklandiae 12g, Radix Glycyrrhizae 6g, Radix Rehmanniae 12g.
The present embodiment be used for the treatment of that thoracic wall is dampened, the Chinese medicine preparation of fracture of rib is decoction, make primarily of above-mentioned Chinese medicine composition.Preparation method comprises and measures Chinese medicine composition by formula and be placed in sand tank, adds water and makes the water surface exceed powder 3cm, use slow fire instead and boil 20min after intense fire boils, filter to obtain decocting liquid; Added water by filtering residue, the water surface exceeds powder 3cm, uses slow fire instead and boil 20min after intense fire boils, and filters secondary decocting liquid, merges twice decocting liquid, obtain decoction.
When described decoction is taken every day potion, every agent 450 ~ 550ml, under point 2 ~ 3 taking medicine after meales, 10th is a course for the treatment of.
Embodiment 2
The Chinese medicine composition being used for the treatment of thoracic wall contusion, fracture of rib of the present embodiment, is made up of the component of following weight: Radix Bupleuri 3g, Semen Persicae 12g, Flos Carthami 9g, Radix Angelicae Sinensis 9g, Rhizoma Chuanxiong 6g, Radix Paeoniae Rubra 6g, Radix Achyranthis Bidentatae 9g, Radix Salviae Miltiorrhizae 12g, Fructus Aurantii 6g, Radix Platycodonis 5g, Rhizoma Corydalis 15g, Radix Aucklandiae 10g, Radix Glycyrrhizae 6g, Radix Rehmanniae 9g.
The present embodiment be used for the treatment of that thoracic wall is dampened, the Chinese medicine preparation of fracture of rib is powder, be made up of above-mentioned Chinese medicine composition.Preparation method is: measure Chinese medicine composition by formula, is crushed to 120 order fine powders, obtained powder.Or obtain capsule by encapsulated for gained fine powder.
The instructions of taking of described capsule is: each 2 ~ 4g, three times on the one.
Embodiment 3
The Chinese medicine composition being used for the treatment of thoracic wall contusion, fracture of rib of the present embodiment, is made up of the component of following weight: Radix Bupleuri 3g, Semen Persicae 12g, Flos Carthami 9g, Radix Angelicae Sinensis 9g, Rhizoma Chuanxiong 9g, Radix Paeoniae Rubra 9g, Radix Achyranthis Bidentatae 12g, Radix Salviae Miltiorrhizae 9g, Fructus Aurantii 6g, Radix Platycodonis 6g, Rhizoma Corydalis 12g, Radix Aucklandiae 12g, Radix Glycyrrhizae 6g, Radix Rehmanniae 6g.
The present embodiment be used for the treatment of that thoracic wall is dampened, the Chinese drug-treated group preparation of fracture of rib is pill, make primarily of above-mentioned Chinese medicine composition.Preparation method comprises the following steps:
1) measure above-mentioned Chinese medicine composition by formula, pulverize and after crossing 120 mesh sieves, in 100 DEG C of sterilizing 30min, obtain powder;
2) be the ratio of 100:30 according to the mass ratio of powder and middle honey, after being mixed with middle honey by powder, mix homogeneously after being heated to 70 DEG C with boiled water, make the pellet that weight is 0.3g after concise 3 times, rear 60 DEG C of dryings, obtain honeyed pill.
The instructions of taking of described honeyed pill is: each 3 ~ 6g, a twice-daily.
Embodiment 4-8 is used for the treatment of that thoracic wall is dampened, the formula of fracture of rib Chinese medicine composition is as shown in table 1.
The formula of the Chinese medicine composition of table 1 embodiment 4-8
Embodiment 4-8 is used for the treatment of that thoracic wall is dampened, the Chinese medicine preparation of fracture of rib can be decoction, powder (or capsule), pill, and the preparation method of each preparation is respectively with embodiment 1, embodiment 2 or embodiment 3.
Clinical test results is as follows:
(1) physical data
All thoracic wall are dampened, fracture of rib MethodsThe cases enrolled is slight, moderate surgical patients, get rid of severe patient, anemia of pregnant woman, have serious gastroduodenal ulcer history patient and have organ disease person, the hyperactivity of fire caused by deficiency of YIN such as serious brain, liver, kidney, upper excess and lower deficiency and the weak people of gas.Selected 61 examples altogether, wherein man 32 example, female 29 example, 40 ~ 75 years old age.In 61 routine MethodsThe cases enrolled, the thoracic wall that wherein caused by violence wound is dampened, fracture of rib is 55 examples, and what external force and senile osteoporosis were that main cause causes is 6 examples.
(2) research method
The selected patient of 61 example is divided into two groups, treatment group 31 example, matched group 30 example.
The decoction that the Chinese medicine composition that treatment group takes the embodiment of the present invention 1 is made, a twice-daily, every day potion, one after each meal.
Matched group gives medicine pain relieving, promotes rehabilitation nutrition medicine: medicine blood circulation promoting and blood stasis dispelling, once-a-day oral traumatology pill for traumatic injuries.
Two groups in treatments period other Medicine diseases can continue as usual treatment.It within 15 days, is 1 course for the treatment of.
(3) curative effect determinate standard
Cure: thoracic wall is dampened, fracture of rib healing; Effective: thoracic wall is dampened, fracture of rib symptom obviously alleviates; Effective: thoracic wall is dampened, fracture of rib symptom is improved; Invalid: thoracic wall contusion, fracture of rib are without improvement.
(4) result of study
Treat after 90 days, two groups of comparitive study results are as shown in table 2.
Table 2 liang group comparitive study result
| Group | Number of cases | Cure | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 31 | 24 | 3 | 2 | 2 | 93.54 |
| Matched group | 30 | 10 | 6 | 4 | 10 | 66.67 |
(5) conclusion
Treat after 30 days, the total effective rate for the treatment of group to thoracic wall contusion, fracture of rib is 93.54%, is significantly higher than 66.67% (P<0.01) of matched group.Experimental result shows, Chinese medicine composition of the present invention is dampened thoracic wall, fracture of rib has significant curative effect.Take Chinese medicine composition of the present invention and do not occur the untoward reaction such as hepatic and renal function injure, show that Chinese medicine composition of the present invention has good safety.
The capsule that the thoracic wall of experimental example 2 ~ 8 is dampened, fracture of rib patient takes embodiment 2 ~ 8 successively respectively, decoction or honeyed pill, specific experiment method is with experimental example 1, and therapeutic effect is in table 2:
The comparative result of table 2 experimental example 2 ~ 8 curative effect
Conclusion: treat after 20 days, treatment group is dampened thoracic wall, the total effective rate of fracture of rib is 78.95 ~ 89.74%, is significantly higher than 60.00 ~ 65.71% (P<0.01) of matched group.Experimental result shows, Chinese medicine composition of the present invention is dampened thoracic wall, fracture of rib has significant curative effect; Take Chinese medicine composition of the present invention and do not occur the untoward reaction such as hepatic and renal function injure, show that Chinese medicine composition of the present invention has good safety.
Model case
Model case 1: Fushan City, Guangdong Province Mr. Zhao, 55 years old, fracture of rib, take the Chinese medicine activating blood and resolving stasis and treatings such as notoginseng preparations invalid, while surgery conventional therapy, the decoction that the Chinese medicine composition taking the employing embodiment of the present invention 4 for 2 times on the one is made is after 30 days, and fracture of rib symptom is improved, and takes posterior rib union of fracture in 90 days.
Model case 2: Yiyang County, Henan Province Mrs Liu, 48 years old, thoracic wall was dampened, and repeatedly through the treatment such as acupuncture-moxibustion, Chinese medicine blood circulation promoting and blood stasis dispelling weak curative effect, took the decoction 20 days posterior chest walls adopting the Chinese medicine composition of the embodiment of the present invention 5 to make for 2 times on the one and dampened symptom improvement.
Model case 3: Guangdong Province Gaoming City Mr. Zhang, 61 years old, fracture of rib, take the Chinese medicine activating blood and resolving stasis and treatings such as notoginseng preparations invalid, while surgery conventional therapy, each 2 ~ 4g, the capsule that the Chinese medicine composition taking the employing embodiment of the present invention 2 for 3 times on the one is made is after 30 days, fracture of rib symptom is improved, and takes posterior rib union of fracture in 90 days.
Model case 4: Luoyang City Mr. Tian, 70 years old, thoracic wall is dampened, through the treatment such as acupuncture-moxibustion, Chinese medicine blood circulation promoting and blood stasis dispelling weak curative effect, while conventional therapy, each 2 ~ 4g, the capsule that the Chinese medicine composition taking the employing embodiment of the present invention 6 for 3 times on the one is made is after 20 days, and thoracic wall is dampened symptom and obviously improved.
Model case 5: Guangxi province Nanning City Mrs Li, 55 years old, fracture of rib, take the Chinese medicine activating blood and resolving stasis and treatings such as notoginseng preparations invalid, while surgery conventional therapy, each 3 ~ 6g, the pill that the Chinese medicine composition taking the employing embodiment of the present invention 3 for 2 times on the one is made is after 30 days, fracture of rib symptom is improved, and takes posterior rib union of fracture in 90 days.
Model case 7: Kaifeng, Henan Province Mrs Wang, 60 years old, thoracic wall was dampened, and takes Chinese medicine activating blood and resolving stasis and treating invalid, each 3 ~ 6g, and the pill that the Chinese medicine composition taking the employing embodiment of the present invention 7 for 2 times on the one is made is after 20 days, and thoracic wall is dampened symptom and improved.
Claims (10)
1. be used for the treatment of a Chinese medicine composition for thoracic wall contusion, fracture of rib, it is characterized in that: be made up of the component of following parts by weight: Radix Bupleuri 3 ~ 15 parts, 6 ~ 12 parts, Semen Persicae, 3 ~ 9 parts, Flos Carthami, Radix Angelicae Sinensis 6 ~ 15 parts, Rhizoma Chuanxiong 3 ~ 12 parts, Radix Paeoniae Rubra 6 ~ 12 parts, Radix Achyranthis Bidentatae 6 ~ 15 parts, Radix Salviae Miltiorrhizae 3 ~ 15 parts, Fructus Aurantii 6 ~ 9 parts, Radix Platycodonis 3 ~ 10 parts, Rhizoma Corydalis 6 ~ 15 parts, the Radix Aucklandiae 2 ~ 12 parts, 3 ~ 6 parts, Radix Glycyrrhizae, 6 ~ 15 parts, the Radix Rehmanniae.
2. the Chinese medicine composition being used for the treatment of thoracic wall contusion, fracture of rib according to claim 1, is characterized in that: be made up of the component of following parts by weight: Radix Bupleuri 15 parts, 12 parts, Semen Persicae, 9 parts, Flos Carthami, Radix Angelicae Sinensis 9 parts, Rhizoma Chuanxiong 12 parts, Radix Paeoniae Rubra 12 parts, Radix Achyranthis Bidentatae 12 parts, Radix Salviae Miltiorrhizae 12 parts, Fructus Aurantii 9 parts, Radix Platycodonis 10 parts, Rhizoma Corydalis 15 parts, the Radix Aucklandiae 12 parts, 6 parts, Radix Glycyrrhizae, 12 parts, the Radix Rehmanniae.
3. be used for the treatment of a Chinese medicine preparation for thoracic wall contusion, fracture of rib, it is characterized in that: the raw material primarily of following parts by weight is made: Radix Bupleuri 3 ~ 15 parts, 6 ~ 12 parts, Semen Persicae, 3 ~ 9 parts, Flos Carthami, Radix Angelicae Sinensis 6 ~ 15 parts, Rhizoma Chuanxiong 3 ~ 12 parts, Radix Paeoniae Rubra 6 ~ 12 parts, Radix Achyranthis Bidentatae 6 ~ 15 parts, Radix Salviae Miltiorrhizae 3 ~ 15 parts, Fructus Aurantii 6 ~ 9 parts, Radix Platycodonis 3 ~ 10 parts, Rhizoma Corydalis 6 ~ 15 parts, the Radix Aucklandiae 2 ~ 12 parts, 3 ~ 6 parts, Radix Glycyrrhizae, 6 ~ 15 parts, the Radix Rehmanniae.
4. the Chinese medicine preparation being used for the treatment of thoracic wall contusion, fracture of rib according to claim 3, is characterized in that: described Chinese medicine preparation is powder, capsule, decoction or pill.
5. be used for the treatment of that thoracic wall is dampened, a preparation method for the Chinese medicine preparation of fracture of rib as claimed in claim 4, it is characterized in that: comprise and measure raw material by formula, decoct with water for twice, collecting decoction, obtain decoction.
6. be used for the treatment of that thoracic wall is dampened, a preparation method for the Chinese medicine preparation of fracture of rib as claimed in claim 4, it is characterized in that, comprise and measure raw material by formula, be crushed to 100 ~ 150 order fine powders, obtained powder or encapsulated capsule.
7. be used for the treatment of that thoracic wall is dampened, a preparation method for the Chinese medicine preparation of fracture of rib as claimed in claim 4, it is characterized in that, comprise the following steps:
1) measure raw material by formula, to pulverize and after sieving, sterilizing, obtains powder;
2) be the ratio of 100:30 according to the mass ratio of powder and middle honey, after being mixed with middle honey by powder, be heated to 65 ~ 75 DEG C and mix homogeneously with boiled water, make pellet after concise 3 times, rear drying, obtains honeyed pill.
8. be according to claim 7ly used for the treatment of that thoracic wall is dampened, the preparation method of the Chinese medicine preparation of fracture of rib, it is characterized in that: step 1) in, described in sieve and referred to 100 ~ 150 mesh sieves.
9. be according to claim 7ly used for the treatment of that thoracic wall is dampened, the preparation method of the Chinese medicine preparation of fracture of rib, it is characterized in that: step 1) in, described sterilizing is at 100 DEG C of sterilizing 30min.
10. be according to claim 7ly used for the treatment of that thoracic wall is dampened, the preparation method of the Chinese medicine preparation of fracture of rib, it is characterized in that: step 2) in, the temperature of described drying is 55 ~ 65 DEG C.
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| CN108785421A (en) * | 2017-05-01 | 2018-11-13 | 王晓霞 | A kind of Chinese medicine preparation and its preparation method for treating fracture |
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| CN105726757A (en) * | 2016-04-29 | 2016-07-06 | 王发堂 | Ginseng stasis-removing blood-promoting traditional Chinese medicine for treating cardio-cerebral stasis |
| CN108785421A (en) * | 2017-05-01 | 2018-11-13 | 王晓霞 | A kind of Chinese medicine preparation and its preparation method for treating fracture |
| CN108785421B (en) * | 2017-05-01 | 2021-07-27 | 王晓霞 | A Chinese medicinal composition for treating fracture and its preparation method |
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