CN105169031A - Medicament for treating heatstroke and preparation method of medicament - Google Patents
Medicament for treating heatstroke and preparation method of medicament Download PDFInfo
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Abstract
The invention discloses a medicament for treating heatstroke. The medicament is mainly prepared from the following active pharmaceutical ingredients in parts by mass: 9 to 16 parts of euonymus laxiflorus, 10 to 15 parts of whole herb of thesium longifolium rurcaz, 8 to 14 parts of heliotropium indicum, 9 to 15 parts of herb of sword brake, 11 to 17 parts of honeysuckle, 8 to 16 parts of salsola collina, 9 to 12 parts of tylophora florlbunda, 7 to 15 parts of omei meadowrue, 9 to 13 parts of mung bean, 6 to 14 parts of carduus crispus, 9 to 17 parts of talinum paniculatum, 10 to 14 parts of solanum photeinocarpum nakamura et odashima, 12 to 18 parts of bamboo leaves and 8 to 13 parts of abelmoschus moschatus. The medicament disclosed by the invention is prepared by clinical practices and summarization for many years, has the efficacies of eliminating summer-heat by cooling, and tonifying qi and moistening lung, and is significant in curative effect.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to medicament for the treatment of heatstroke and preparation method thereof.
Background technology
Heatstroke refers under high temperature and thermal-radiating long duration of action, body thermoregulatory dysfunctions, the general name of the symptom of water and electrolyte metabolism disorder and nervous function infringement.The degree of heatstroke can be divided into three grades: 1. premonitory heatstroke.In hot environment, a large amount of to perspire, thirsty, dizzy, tinnitus, uncomfortable in chest, cardiopalmus, nauseating, myasthenia of limbs, absent minded, body temperature is no more than 37.5 DEG C; 2. mild heat stroke.Have the symptom of premonitory heatstroke, simultaneously body temperature is more than 38.5 DEG C, and with phenomenons such as flushed face, uncomfortable in chest, skin burns; Or skin is clammy, vomiting, blood pressure drops, situation that pulse is thin and fast; 3. severe heat stroke.Except above symptom, occur to faint or spasm; Or do not perspire, body temperature is more than 40 DEG C.
Publication No. CN104083435A(application number 201410270975.6) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of heatstroke, its raw material is; Radix Ginseng 2 parts, Herba Artemisiae Annuae 5 parts, Herba Moslae 8 parts, the Rhizoma Atractylodis Macrocephalae 10 parts.Described ointment preparation method: take raw material Radix Ginseng 2 parts, Herba Artemisiae Annuae 5 parts, Herba Moslae 8 parts, the Rhizoma Atractylodis Macrocephalae 10 parts make decoction pieces respectively, through pressure cooker cooking disinfection 30-60 minute, dry, obtain aseptic raw material; The aseptic raw material obtained makes Chinese medicine preparation.Publication No. CN104173793A(application number 201410352783.X) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of heatstroke, its raw medicinal material respectively: Flos Chrysanthemi Indici 10 parts, Herba Menthae 10 parts, Herba Pogostemonis 15 parts, Semen oryzae sativae 50 parts, 15 parts, Folium Nelumbinis, Flos Lonicerae 50 parts, Fructus Crataegi 20 parts.Publication No. CN104173434A(application number 201310223966.7) Chinese patent literature disclose a kind of Chinese medicine for the treatment of heatstroke, it is characterized in that it is made up of the component of following weight portion: Radix agastaches 13-17 gram, Herba Artemisiae Annuae 13-17 gram.
Although the Chinese medicine being used for the treatment of heatstroke at present has much, curative effect is uneven, and taste is poor, therefore needs to develop a kind of Chinese medicine formula being more applicable to patient and taking.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, the medicament taking the wide treatment heatstroke of safe and applicable and preparation method thereof.
Technical scheme of the present invention is:
The medicament for the treatment of heatstroke, is prepared from primarily of following bulk drugs, is mass parts: mountain Cortex Eucommiae 9-16; Herba Thesii Longifolii 10-15; Herba Heliotroph 8-14; Herba Pteridis Ensiformis 9-15; Flos Lonicerae 11-17; Herba Salsolae Collinae 8-16; Tylophora florlbunda 9-12; Thalictrum omeiense W. T. Wang et S. H. Wang 7-15; Semen phaseoli radiati 9-13; Herba Cardui Crispi 6-14; Radix Talini Paniculati 9-17; Herba solani photeinocarpi 10-14; Folium Bambusae 12-18; Radix seu folium abelmoschi moschati 8-13.
Preferred version is, mountain Cortex Eucommiae 11-14; Herba Thesii Longifolii 12-13; Herba Heliotroph 10-12; Herba Pteridis Ensiformis 11-13; Flos Lonicerae 13-15; Herba Salsolae Collinae 10-14; Tylophora florlbunda 10-11; Thalictrum omeiense W. T. Wang et S. H. Wang 9-13; Semen phaseoli radiati 10-12; Herba Cardui Crispi 8-12; Radix Talini Paniculati 11-15; Herba solani photeinocarpi 11-13; Folium Bambusae 14-16; Radix seu folium abelmoschi moschati 9-12.
More preferably, the mountain Cortex Eucommiae 12.5; Herba Thesii Longifolii 12.5; Herba Heliotroph 11; Herba Pteridis Ensiformis 12; Flos Lonicerae 14; Herba Salsolae Collinae 12; Tylophora florlbunda 10.5; Thalictrum omeiense W. T. Wang et S. H. Wang 11; Semen phaseoli radiati 11; Herba Cardui Crispi 10; Radix Talini Paniculati 13; Herba solani photeinocarpi 12; Folium Bambusae 15; Radix seu folium abelmoschi moschati 10.5.
The medicament of described treatment heatstroke, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean by Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati, mix thoroughly with Sucus Zingberis, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, decoct with water, big fire is boiled to boiling, lasting 10 minutes, changes little fiery continuation decoction 15-25 minute (preferred: continuation decoction 18-22 minute; Be more preferably: continue decoction 20 minutes), close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, constant temperature drying, pulverize together with step (1) (2) made crude drug;
(5) by step (3) (4) gained filtrate and medicated powder mixing, add decocting in water to boiling, after filtration, obtain decoction.
The preparation method of the medicament decoction of described treatment heatstroke, step (3) amount of water is that the 9-12 of Semen phaseoli radiati quality is doubly (preferred: amount of water is 10-11 times of Semen phaseoli radiati quality; Be more preferably: amount of water is 10.5 times of Semen phaseoli radiati quality).
The medicament of described treatment heatstroke, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean by Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati, mix thoroughly with Sucus Zingberis, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, lasting 10 minutes, changes little fiery continuation decoction 15-25 minute (preferred: continuation decoction 18-22 minute; Be more preferably: continue decoction 20 minutes), close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, constant temperature drying, pulverize and sieve together with step (1) (2) made crude drug;
(5) spray drying step (3) gained filtrate, mixes with step (4) gained medicated powder after pulverizing, obtains powder.
The preparation method of the medicament powder of described treatment heatstroke, it is (preferred: to pulverize 180-200 mesh sieve that step (4) pulverized 160-220 mesh sieve; Be more preferably: pulverized 190 mesh sieves).
The medicament of described treatment heatstroke, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean by Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati, mix thoroughly with Sucus Zingberis, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, lasting 10 minutes, changes little fiery continuation decoction 15-25 minute (preferred: continuation decoction 18-22 minute; Be more preferably: continue decoction 20 minutes), close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, constant temperature drying;
(5) concentration step (3) gained filtrate drying, pulverizes and sieves dry thing together with step (1) (2) (4) made crude drug, adds water generally to make ball, obtains pill.
The preparation method of the medicament pill of described treatment heatstroke, it is (preferred: to pulverize 110-130 mesh sieve that step (5) pulverized 90-150 mesh sieve; Be more preferably: pulverized 120 mesh sieves).
The medicament of described treatment heatstroke, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean by Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati, mix thoroughly with Sucus Zingberis, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, lasting 10 minutes, changes little fiery continuation decoction 15-25 minute (preferred: continuation decoction 18-22 minute; Be more preferably: continue decoction 20 minutes), close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, constant temperature drying;
(5) concentration step (3) gained filtrate drying, pulverized 100 mesh sieves by dry thing, and was packed in capsule, obtains capsule together with step (1) (2) (4) made crude drug.
The preparation method of the drug capsule agent of described treatment heatstroke, in the every capsules of step (5), contained medicated powder weight is that 0.3-0.5g(is preferred: in every capsules, contained medicated powder weight is 0.35-0.45g; Be more preferably: in every capsules, contained medicated powder weight is 0.4g).
The reagent combination science for the treatment of heatstroke provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, effectively can prevent recurrence;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of clearing away summer-heat, qi invigorating and lung moistening;
3, Chinese crude drug selected by the present invention, safety has no side effect, and treatment time is short, instant effect.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
embodiment 1the medicament for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: the mountain Cortex Eucommiae 9 parts, Herba Thesii Longifolii 10 parts, Herba Heliotroph 8 parts, Herba Pteridis Ensiformis 9 parts, Flos Lonicerae 11 parts, Herba Salsolae Collinae 8 parts, tylophora florlbunda 9 parts, Thalictrum omeiense W. T. Wang et S. H. Wang 7 parts, 9 parts, Semen phaseoli radiati, Herba Cardui Crispi 6 parts, Radix Talini Paniculati 9 parts, Herba solani photeinocarpi 10 parts, 12 parts, Folium Bambusae, Radix seu folium abelmoschi moschati 8 parts.The preparation method of the medicament decoction of above-mentioned treatment heatstroke is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean, mix thoroughly Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati with Sucus Zingberis, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 10.5 times, big fire is boiled to boiling, continues 10 minutes, changes little fire and continues decoction 20 minutes, close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, constant temperature drying, pulverize together with step (1) (2) made crude drug;
(5) by step (3) (4) gained filtrate and medicated powder mixing, add decocting in water to boiling, after filtration, obtain decoction.
embodiment 2the medicament for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: the mountain Cortex Eucommiae 16 parts, Herba Thesii Longifolii 15 parts, Herba Heliotroph 14 parts, Herba Pteridis Ensiformis 15 parts, Flos Lonicerae 17 parts, Herba Salsolae Collinae 16 parts, tylophora florlbunda 12 parts, Thalictrum omeiense W. T. Wang et S. H. Wang 15 parts, 13 parts, Semen phaseoli radiati, Herba Cardui Crispi 14 parts, Radix Talini Paniculati 17 parts, Herba solani photeinocarpi 14 parts, 18 parts, Folium Bambusae, Radix seu folium abelmoschi moschati 13 parts.The preparation method of the medicament powder of above-mentioned treatment heatstroke is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean, mix thoroughly Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati with Sucus Zingberis, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, continues 10 minutes, changes little fire and continues decoction 20 minutes, close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, constant temperature drying, pulverized 190 mesh sieves together with step (1) (2) made crude drug;
(5) spray drying step (3) gained filtrate, mixes with step (4) gained medicated powder after pulverizing, obtains powder.
Model case: xxx, male, 38 years old.Patient is truck driver, and when noon drives, self-induction is uncomfortable, perspires serious, dizziness and blurred vision, and attention can not be concentrated, and with the symptom such as to feel sick uncomfortable in chest, on inspection, patient temperature 38.6 DEG C, palpitates quickly, and is diagnosed as mild heat stroke.
Taking this example gained powder, each 3-4g, warm boiled water, one day twice, three days is a course for the treatment of, and after patient takes one day, the transference cures such as dizziness and nausea, health recovers gradually, and after adhering to taking a course for the treatment of, uncomfortable disease is all eliminated, and patient fully recovers.
embodiment 3the medicament for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: the mountain Cortex Eucommiae 11 parts, Herba Thesii Longifolii 12 parts, Herba Heliotroph 10 parts, Herba Pteridis Ensiformis 11 parts, Flos Lonicerae 13 parts, Herba Salsolae Collinae 10 parts, tylophora florlbunda 10 parts, Thalictrum omeiense W. T. Wang et S. H. Wang 9 parts, 10 parts, Semen phaseoli radiati, Herba Cardui Crispi 8 parts, Radix Talini Paniculati 11 parts, Herba solani photeinocarpi 11 parts, 14 parts, Folium Bambusae, Radix seu folium abelmoschi moschati 9 parts.The preparation method of the medicament pill of above-mentioned treatment heatstroke is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean, mix thoroughly Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati with Sucus Zingberis, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, continues 10 minutes, changes little fire and continues decoction 20 minutes, close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, constant temperature drying;
(5) concentration step (3) gained filtrate drying, pulverized 120 mesh sieves by dry thing together with step (1) (2) (4) made crude drug, added water generally to make ball, obtained pill.
Model case: xxx, women, 46 years old.Medical history: patient works two days in high temperature environments, beginning body is tired weak, hyperhidrosis, skin burns, in order to not dally over one's work, hold on working, fell in a swoon suddenly on ground before half an hour, confusion, check after being sent to hospital, body temperature is up to 39.8 DEG C, and skin surface is lossless, is diagnosed as severe heatstroke.
Recommend to take this example gained pill, each 3-4 grain, warm boiled water, one day twice through people, within three days, be a course for the treatment of, after patient takes three hours, body temperature starts to decline, and consciousness recovery is regained consciousness, after taking three days, muscle power and spirit obviously recover normal, and without other untoward reaction, patient fully recovers.
embodiment 4the medicament for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: the mountain Cortex Eucommiae 14 parts, Herba Thesii Longifolii 13 parts, Herba Heliotroph 12 parts, Herba Pteridis Ensiformis 13 parts, Flos Lonicerae 15 parts, Herba Salsolae Collinae 14 parts, tylophora florlbunda 11 parts, Thalictrum omeiense W. T. Wang et S. H. Wang 13 parts, 12 parts, Semen phaseoli radiati, Herba Cardui Crispi 12 parts, Radix Talini Paniculati 15 parts, Herba solani photeinocarpi 13 parts, 16 parts, Folium Bambusae, Radix seu folium abelmoschi moschati 12 parts.The preparation method of the drug capsule agent of above-mentioned treatment heatstroke is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean, mix thoroughly Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati with Sucus Zingberis, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, continues 10 minutes, changes little fire and continues decoction 20 minutes, close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, constant temperature drying;
(5) concentration step (3) gained filtrate drying, pulverized 100 mesh sieves by dry thing, was packed in capsule together with step (1) (2) (4) made crude drug, and in every capsules, contained medicated powder weight is 0.4g, obtains capsule.
Model case: xxx, male, 56 years old.Medical history: patient takes advantage of weekend and goes on a tour together with household, because weather is scorching, self-induction body heat hyperhidrosis, breathe effort, have the symptom of chest distress and palpitation symptoms, alleviate to some extent after rest, but still sensation dizziness and nausea, myasthenia of limbs, after go to clinic to check, be diagnosed as heatstroke.
Taking this example gained capsule, each 3-4 grain, warm boiled water, one day twice, three days is a course for the treatment of, and after patient takes one day, the uncomfortable disease such as dizziness and nausea obviously alleviates, and adhere to taking a course for the treatment of, all diseases disappear entirely, and patient fully recovers.
embodiment 5the medicament for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: the mountain Cortex Eucommiae 12.5 parts, Herba Thesii Longifolii 12.5 parts, Herba Heliotroph 11 parts, Herba Pteridis Ensiformis 12 parts, Flos Lonicerae 14 parts, Herba Salsolae Collinae 12 parts, tylophora florlbunda 10.5 parts, Thalictrum omeiense W. T. Wang et S. H. Wang 11 parts, 11 parts, Semen phaseoli radiati, Herba Cardui Crispi 10 parts, Radix Talini Paniculati 13 parts, Herba solani photeinocarpi 12 parts, 15 parts, Folium Bambusae, Radix seu folium abelmoschi moschati 10.5 parts.The preparation method of the medicament decoction of above-mentioned treatment heatstroke is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean, mix thoroughly Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati with Sucus Zingberis, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 10.5 times, big fire is boiled to boiling, continues 10 minutes, changes little fire and continues decoction 20 minutes, close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, constant temperature drying, pulverize together with step (1) (2) made crude drug;
(5) by step (3) (4) gained filtrate and medicated powder mixing, add decocting in water to boiling, after filtration, obtain decoction.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
The mountain Cortex Eucommiae: base is former: be root and the bark of the Celastraceae plant flower thinning Cortex Eucommiae.Nature and flavor: sweet; Pungent; Tepor.Gui Jing: liver; Kidney; Spleen channel.Function cures mainly: wind-damp dispelling; Bone and muscle strengthening; Promoting blood circulation and detoxication; Diuretic.Main air pain of dampness syndrome; Soreness of the waist and knees; Injury and bone fracture; Sore swollen toxin; Chronic hepatitis; Chronic nephritis; Edema.
Herba Thesii Longifolii: base is former: for Santalaceae plant comes into leaves Herba Thesii, dew post Herba Thesii, the herb of Thesium longifolium Hand.-Mazz. or Thesium refractum C. A. Meyer or root.Nature and flavor: pungent; Micro-hardship; Cool in nature.Gui Jing: lung; Liver; Spleen channel.Function cures mainly: heat clearing away of inducing sweat; Expelling wind and relieving convulsion.Main flu; Heatstroke; Infantile pneumonia; Infantile convulsion.
Herba Heliotroph: base is former: be herb or the root of comfrey Herba Heliotroph.Nature and flavor: bitter; Flat.Gui Jing: lung; Urinary bladder channel.Function cures mainly: diuresis; Detumescence; Removing toxic substances.Main pneumonia; Empyema; Pharyngalgia; Oral erosion; Vesical calculus; Carbuncle.
Herba Pteridis Ensiformis: base is former: be rhizome or the herb of Pteridaceae plant Pteris ensiformis.Chemical analysis: herb is containing flavonoid glycoside, phenols, aminoacid, organic acid.Nature and flavor: bitter; Micro-puckery; Be slightly cold; Slightly poisonous.Gui Jing: liver; Large intestine; Urinary bladder channel.Function cures mainly: heat clearing away; Dampness removing; Cooling blood for hemostasis; Removing toxic substances and promoting subsidence of swelling.Main dysentery; Have loose bowels; Malaria; Jaundice; Gonorrhea; Leucorrhea; Laryngopharynx swelling and pain; Mumps; Carbuncle; Scrofula; Metrorrhagia; Bleeding hemorrhoids; Traumatic hemorrhage; Treating swelling and pain by traumatic injury; Scabies; Eczema.
Flos Lonicerae: sweet in the mouth, micro-hardship, cold nature.Have heat-clearing and toxic substances removing, expelling pathogenic factors from the exterior is gone out, effect of stomach function regulating preventing or arresting vomiting, stops up resistance, disorder of stomach-QI, fever and irritability for pathogenic heat.
Herba Salsolae Collinae: base is former: be the herb of chenopod Herba Salsolae Collinae.Nature and flavor: light; Cool in nature.Gui Jing: Liver Channel.Function cures mainly: suppressing the hyperactive liver and subsiding YANG; Loosening bowel to relieve constipation.Main hypertension; How sick; Dizzy; Insomnia; Dryness of the intestine constipation.
Tylophora florlbunda: base is former: be the root of Luo Ru section Tylophora plant tylophora florlbunda, perennial winding liana, has milk; Root hair shape, faint yellow; Be used as medicine with root.Composition: containing tylophorine, 2,3,5,6-tetramethoxyphenanthro[9,10:6',7', tylophorinine alkali.The property of medicine: pungent, temperature, slightly poisonous.Function cures mainly: dispelling pathogenic wind and eliminating phlegm, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling.Cure mainly cough with asthma abundant expectoration, diphtheria, infantile convulsion, rheumatic arthralgia, traumatic injury, fracture, venom, carbuncle furuncle, acute conjunctivitis, stomatitis, edema, hepatosplenomegaly.
Thalictrum omeiense W. T. Wang et S. H. Wang: base is former: be the herb of the high eyebrow Thalictrum aquilegifolium L. var. sibiricum Regel of ranunculaceae plant.Nature and flavor: bitter in the mouth; Cold in nature.Gui Jing: return liver; Large intestine channel.Function cures mainly: heat clearing and damp drying; Liver heat removing and eyesight improving; Preventing the attack (or recurrence) of malaria.Cure mainly jaundice due to damp-heat, stomachache dysentery; Conjunctival congestion and swelling pain; Malaria cold and heat.
Semen phaseoli radiati: base is former: be the seed of leguminous plant Semen phaseoli radiati.Nature and flavor: sweet in the mouth; Cold in nature.Gui Jing: the heart; Stomach warp.Function cures mainly: heat clearing away; Relieve summer heat; Diuretic; Removing toxic substances.Main summer-heat excessive thirst; Cold, fever; Cholera is vomited and diarrhoea; Expectorant asthma of heat type is breathed heavily; Headache conjunctival congestion; Aphtha of the mouth and tongue; Edema oliguria; Skin infection carbuncle; Rubella erysipelas; Medicine and alimentary toxicosis.
Herba Cardui Crispi: base is former: be feverfew silk hair Herba Cardui Crispi and the herb or the root that save hair Herba Cardui Crispi.Nature and flavor: mildly bitter flavor; Cool in nature.Function cures mainly: dispel the wind; Heat clearing away; Dampness removing; Cooling blood for hemostasis; Promoting blood circulation and detumescence.Main cold cough; Have a headache dizzy; Urinary system infection; Chyluria; Leucorrhea; Jaundice; Rheumatic arthralgia; Spit blood; Epistaxis; Hematuria; Menorrhagia; Dysfunctional uterine hemorrhage; Traumatic injury; Furuncle furuncle and phyma; Swelling and pain of hemorrhoid; Burn.
Radix Talini Paniculati: base is former: be the root of portulacaceous plant smoke tree orchid.Nature and flavor: sweet; Light; Property is put down.Gui Jing: spleen; Lung; Kidney channel.Function cures mainly: qi invigorating and lung moistening; Cough-relieving; Regulating menstruation.Main deficiency of vital energy sesame is tired; Lack of appetite; Have loose bowels; Pulmonary tuberculosis hemoptysis; Dizzy; Hectic fever; Night sweat; Spontaneous perspiration; Menoxenia; Leukorrhagia, paturient's hypogalactia.
Herba solani photeinocarpi: base is former: be the herb of plant of Solanaceae S. photeinocarpum.Nature and flavor: mildly bitter flavor; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Inducing diuresis and reducing edema.Main hypertension; Dysentery; Pyretic stranguria; Conjunctival congestion; Laryngopharynx swelling and pain; Furuncle furuncle and phyma.
Folium Bambusae: base is former: be the leaf of grass phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle etc.Nature and flavor: sweet; Light; Cold.Gui Jing: the heart; Lung; Stomach warp.Function cures mainly: clearing heat and relieving fidgetness; To promote the production of body fluid diuresis.Main calentura excessive thirst; little Jing Epilepsy; Cough with dyspnea tells nosebleed; Oliguria with reddish urine; Erosion of the oral mucosa tongue boil.
Radix seu folium abelmoschi moschati: base is former: be the Herb of Malvaceae plant Radix seu folium abelmoschi moschati.Nature and flavor: micro-sweet; Cold in nature.Gui Jing: the heart; Lung meridian.Function cures mainly: heat-clearing and toxic substances removing; Stimulating milk secretion relieving constipation.Main hyperpyrexia; Cough due to lung-heat; Dysentery; Constipation; Puerperal galactostasis; Fracture; Carbuncle skin ulcer pus swells; Innominate toxic swelling and water inflammation are scalded.
test example 1the clinical practice of the medicament (embodiment 5) of gained treatment heatstroke of the present invention:
Choose crowd: in April, 2014 in December ,-2014, three hospital screening heatstroke patient 253 examples, age 15-65 year, 32.8 ± 2.4 years old mean age, course of disease 0.5-21 hour, male patient 129 example, female patient 124 example, wherein premonitory heatstroke patient 96 example, mild heat stroke patient 119 example, severe heat stroke patient 38 example.Inclusion criteria: all morbidity just all have headache in various degree, giddy, thirsty, hyperhidrosis, the performance such as weak, absent minded, and the symptom such as respiratory frequency and alteration in heart rate, appears in minimizing of then perspiring.
Before test, patient is divided into two groups at random, experimental group 150 example and matched group 103 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 100-200ml, one day twice, warmly takes, and within three days, is a course for the treatment of; Matched group takes other conventional medicines (HUOXIANG ZHENGQI SHUI, rheocamphoradin, LIUYI SAN etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptoms and sign all disappear, and blood pressure, pulse, breathing, body temperature all recover normal, and every test rating is all normal; (2) effective: clinical symptoms and sign alleviate, normally, every laboratory indexes is tending towards normal for blood pressure, pulse, breathing, temperature recovery; (3) invalid: clinical symptoms and sign are without improvement or increase the weight of.
Clinical effectiveness: after the taking medicine an of course for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the healing patient of experimental group is 112 examples, and cure rate is 74.7%, and effective patient is 38 examples, total effective rate is 100%, and the patient that matched group is cured is 62 examples, cure rate is 60.2%, and effective patient is 31 examples, total effective rate 90.3%, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
The Chinese medicine used in the present invention, the mountain Cortex Eucommiae can promoting blood circulation and detoxication, and Herba Thesii Longifolii can induce sweat heat clearing away, Herba Heliotroph can diuresis removing toxic substances, and Herba Pteridis Ensiformis can clearing away heat-damp and promoting diuresis, and Flos Lonicerae can heat-clearing and toxic substances removing, Herba Salsolae Collinae can suppressing the hyperactive liver and subsiding YANG, and tylophora florlbunda can dispelling pathogenic wind and eliminating phlegm, and Thalictrum omeiense W. T. Wang et S. H. Wang can heat clearing and damp drying, Semen phaseoli radiati can clearing away heat and removing summer, and Herba Cardui Crispi can cooling blood for hemostasis, and Radix Talini Paniculati can qi invigorating and lung moistening, Herba solani photeinocarpi can be inducing diuresis and reducing edema, and Folium Bambusae can clearing heat and relieving fidgetness, and Radix seu folium abelmoschi moschati can heat-clearing and toxic substances removing, multiple medical material synergism, plays effect of clearing away summer-heat, qi invigorating and lung moistening altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the medicament of heatstroke, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: mountain Cortex Eucommiae 9-16; Herba Thesii Longifolii 10-15; Herba Heliotroph 8-14; Herba Pteridis Ensiformis 9-15; Flos Lonicerae 11-17; Herba Salsolae Collinae 8-16; Tylophora florlbunda 9-12; Thalictrum omeiense W. T. Wang et S. H. Wang 7-15; Semen phaseoli radiati 9-13; Herba Cardui Crispi 6-14; Radix Talini Paniculati 9-17; Herba solani photeinocarpi 10-14; Folium Bambusae 12-18; Radix seu folium abelmoschi moschati 8-13.
2. the medicament for the treatment of heatstroke as claimed in claim 1, is characterized in that, mountain Cortex Eucommiae 11-14; Herba Thesii Longifolii 12-13; Herba Heliotroph 10-12; Herba Pteridis Ensiformis 11-13; Flos Lonicerae 13-15; Herba Salsolae Collinae 10-14; Tylophora florlbunda 10-11; Thalictrum omeiense W. T. Wang et S. H. Wang 9-13; Semen phaseoli radiati 10-12; Herba Cardui Crispi 8-12; Radix Talini Paniculati 11-15; Herba solani photeinocarpi 11-13; Folium Bambusae 14-16; Radix seu folium abelmoschi moschati 9-12(is preferably: the mountain Cortex Eucommiae 12.5; Herba Thesii Longifolii 12.5; Herba Heliotroph 11; Herba Pteridis Ensiformis 12; Flos Lonicerae 14; Herba Salsolae Collinae 12; Tylophora florlbunda 10.5; Thalictrum omeiense W. T. Wang et S. H. Wang 11; Semen phaseoli radiati 11; Herba Cardui Crispi 10; Radix Talini Paniculati 13; Herba solani photeinocarpi 12; Folium Bambusae 15; Radix seu folium abelmoschi moschati 10.5).
3. the medicament of the treatment heatstroke as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean by Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati, mix thoroughly with Sucus Zingberis, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, decoct with water, big fire is boiled to boiling, lasting 10 minutes, changes little fiery continuation decoction 15-25 minute (preferred: continuation decoction 18-22 minute; Be more preferably: continue decoction 20 minutes), close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, constant temperature drying, pulverize together with step (1) (2) made crude drug;
(5) by step (3) (4) gained filtrate and medicated powder mixing, add decocting in water to boiling, after filtration, obtain decoction.
4. the preparation method of the medicament decoction for the treatment of heatstroke as claimed in claim 3, is characterized in that, step (3) amount of water is that the 9-12 of Semen phaseoli radiati quality is doubly (preferred: amount of water is 10-11 times of Semen phaseoli radiati quality; Be more preferably: amount of water is 10.5 times of Semen phaseoli radiati quality).
5. the medicament of the treatment heatstroke as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean by Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati, mix thoroughly with Sucus Zingberis, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, lasting 10 minutes, changes little fiery continuation decoction 15-25 minute (preferred: continuation decoction 18-22 minute; Be more preferably: continue decoction 20 minutes), close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, constant temperature drying, pulverize and sieve together with step (1) (2) made crude drug;
(5) spray drying step (3) gained filtrate, mixes with step (4) gained medicated powder after pulverizing, obtains powder.
6. the preparation method of the medicament powder for the treatment of heatstroke as claimed in claim 5, it is characterized in that, it is (preferred: to pulverize 180-200 mesh sieve that step (4) pulverized 160-220 mesh sieve; Be more preferably: pulverized 190 mesh sieves).
7. the medicament of the treatment heatstroke as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable pill, its preparation method is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean by Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati, mix thoroughly with Sucus Zingberis, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, lasting 10 minutes, changes little fiery continuation decoction 15-25 minute (preferred: continuation decoction 18-22 minute; Be more preferably: continue decoction 20 minutes), close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, constant temperature drying;
(5) concentration step (3) gained filtrate drying, pulverizes and sieves dry thing together with step (1) (2) (4) made crude drug, adds water generally to make ball, obtains pill.
8. the preparation method of the medicament pill for the treatment of heatstroke as claimed in claim 7, it is characterized in that, it is (preferred: to pulverize 110-130 mesh sieve that step (5) pulverized 90-150 mesh sieve; Be more preferably: pulverized 120 mesh sieves).
9. the medicament of the treatment heatstroke as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable capsule, its preparation method is:
(1) get Rhizoma Zingiberis Recens to mash, thin up becomes pasty state, adds water clean by Flos Lonicerae, Herba Salsolae Collinae, Thalictrum omeiense W. T. Wang et S. H. Wang, Herba solani photeinocarpi, Folium Bambusae and Radix seu folium abelmoschi moschati, mix thoroughly with Sucus Zingberis, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get the mountain Cortex Eucommiae, Herba Thesii Longifolii, Herba Heliotroph and Herba Pteridis Ensiformis and clean remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(3) get Semen phaseoli radiati removing impurity, be placed in marmite, add the soak by water of boiled crude drug quality 9 times, big fire is boiled to boiling, lasting 10 minutes, changes little fiery continuation decoction 15-25 minute (preferred: continuation decoction 18-22 minute; Be more preferably: continue decoction 20 minutes), close fire and filter, collect filtrate;
(4) tylophora florlbunda, Herba Cardui Crispi and Radix Talini Paniculati's roguing are cleaned, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, constant temperature drying;
(5) concentration step (3) gained filtrate drying, pulverized 100 mesh sieves by dry thing, and was packed in capsule, obtains capsule together with step (1) (2) (4) made crude drug.
10. the preparation method of the drug capsule agent for the treatment of heatstroke as claimed in claim 9, is characterized in that, in the every capsules of step (5), contained medicated powder weight is that 0.3-0.5g(is preferred: in every capsules, contained medicated powder weight is 0.35-0.45g; Be more preferably: in every capsules, contained medicated powder weight is 0.4g).
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|---|---|---|---|---|
| CN1861151A (en) * | 2005-05-10 | 2006-11-15 | 路开发 | Oral liquor for heatstroke-prevention |
| CN102283298A (en) * | 2011-09-15 | 2011-12-21 | 李雄骥 | Pathogenic fire clearing summer-heat relieving tea |
| CN104173793A (en) * | 2014-07-16 | 2014-12-03 | 周剑峰 | Traditional Chinese medicinal preparation for treating sunstroke |
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2015
- 2015-09-09 CN CN201510568707.7A patent/CN105169031A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1861151A (en) * | 2005-05-10 | 2006-11-15 | 路开发 | Oral liquor for heatstroke-prevention |
| CN102283298A (en) * | 2011-09-15 | 2011-12-21 | 李雄骥 | Pathogenic fire clearing summer-heat relieving tea |
| CN104173793A (en) * | 2014-07-16 | 2014-12-03 | 周剑峰 | Traditional Chinese medicinal preparation for treating sunstroke |
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| Title |
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| 钟敏: "家庭防暑小验方", 《陕西中医学院学报》 * |
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Address after: 725000 healthy city in Shaanxi province Hanbin District Peixin Street No. 64 Jinhua District No. 4 Building 2 unit 201 Applicant after: Zhang Shihai Address before: 250014 Shandong Province, Lixia District, Ji'nan Road, No. 26 liberation Applicant before: Zhang Shihai |
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