CN105106700A - Composition for treating heat stroke and preparation method of composition - Google Patents
Composition for treating heat stroke and preparation method of composition Download PDFInfo
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- CN105106700A CN105106700A CN201510568643.0A CN201510568643A CN105106700A CN 105106700 A CN105106700 A CN 105106700A CN 201510568643 A CN201510568643 A CN 201510568643A CN 105106700 A CN105106700 A CN 105106700A
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Abstract
The invention discloses a composition for treating heat stroke. The composition is mainly prepared from the following raw materials in parts by weight: 11-17 parts of bamboo leaves, 9-15 parts of rabdosia rubescens, 7-13 parts of welted thistle, 8-14 parts of false loosestrife, 7-16 parts of Ixeris chinensis, 9-14 parts of suchow mosla herb, 6-15 parts of melothria heterophylla, 10-16 parts of talinum crassifolium, 8-15 parts of uncaria, 11-16 parts of rattlesnake plantain, 8-13 parts of tylophora florlbunda, 10-14 parts of flos lablab and 9-12 parts of all-grass of shiningfruit night-shade. The composition is summarized by clinical practices for a plurality of years, has the effects of clearing heat, removing exterior syndromes, relieving summer-heat and resolving dampness, and is significant in curative effect.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the composition and method of making the same for the treatment of heatstroke.
Background technology
Heatstroke refers under high temperature and thermal-radiating long duration of action, body thermoregulatory dysfunctions, the general name of the symptom of water and electrolyte metabolism disorder and nervous function infringement.The degree of heatstroke can be divided into three grades: 1. premonitory heatstroke.In hot environment, a large amount of to perspire, thirsty, dizzy, tinnitus, uncomfortable in chest, cardiopalmus, nauseating, myasthenia of limbs, absent minded, body temperature is no more than 37.5 DEG C; 2. mild heat stroke.Have the symptom of premonitory heatstroke, simultaneously body temperature is more than 38.5 DEG C, and with phenomenons such as flushed face, uncomfortable in chest, skin burns; Or skin is clammy, vomiting, blood pressure drops, situation that pulse is thin and fast; 3. severe heat stroke.Except above symptom, occur to faint or spasm; Or do not perspire, body temperature is more than 40 DEG C.
Publication No. CN103768299A(application number 201410077196.4) Chinese patent literature disclose a kind of first aid medicine preparation method for the treatment of heatstroke, to solve the treatment problem of heatstroke.Processed by plurality of Chinese, its composition of raw materials and weight proportion are: Herba Moslae Chinensis 6 ~ 10 parts, Rhizoma Cimicifugae 8 ~ 15 parts, Radix Artemisia ordosicae 8 ~ 15 parts, Rhizoma Acori Calami 6 ~ 10 parts, Pericarpium Citri Reticulatae 6 ~ 10 parts, Rhizoma Alismatis 8 ~ 15 parts, Cortex Phellodendri 6 ~ 10 parts, 8 ~ 15 parts, Pericarpium Citri Reticulatae Viride, Rhizoma Anemones Altaicae 3 ~ 6 parts.Publication No. CN104606648A(application number 201510099544.2) Chinese patent literature disclose a kind of Chinese medicine being used for the treatment of heatstroke, it is prepared from by the raw medicinal material of following weight proportion: Herba Pogostemonis 9 parts, Radix Curcumae 9 parts, Fructus Gardeniae 8 parts, Radix Ophiopogonis 6 parts.Publication No. CN104173793A(application number 201410352783.X) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of heatstroke, its raw medicinal material respectively: Flos Chrysanthemi Indici 10 parts, Herba Menthae 10 parts, Herba Pogostemonis 15 parts, Semen oryzae sativae 50 parts, 15 parts, Folium Nelumbinis, Flos Lonicerae 50 parts, Fructus Crataegi 20 parts.
Although the Chinese medicine being used for the treatment of heatstroke at present has much, curative effect is uneven, and taste is poor, therefore needs to develop a kind of Chinese medicine formula being more applicable to patient and taking.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the composition and method of making the same of the wide treatment heatstroke of safe and applicable.
Technical scheme of the present invention is:
The compositions for the treatment of heatstroke, is prepared from primarily of following bulk drugs, is mass parts: Folium Bambusae 11-17; Rabdosia rubescens 9-15; Herba Cardui Crispi 7-13; Herba Ludwigiae Prostratae 8-14; Herba Ixeritis chinensis 7-16; Herba Moslae Soochowensis 9-14; Thatch melon 6-15; Radix Talini Paniculati 10-16; Ramulus Uncariae Cum Uncis 8-15; Herba goodyearae repentis 11-16; Tylophora florlbunda 8-13; Flos dolichoris 10-14; Herba solani photeinocarpi 9-12.
Preferred version is, Folium Bambusae 12-16; Rabdosia rubescens 11-13; Herba Cardui Crispi 9-11; Herba Ludwigiae Prostratae 10-12; Herba Ixeritis chinensis 9-14; Herba Moslae Soochowensis 11-12; Thatch melon 8-13; Radix Talini Paniculati 12-14; Ramulus Uncariae Cum Uncis 10-13; Herba goodyearae repentis 12-15; Tylophora florlbunda 9-12; Flos dolichoris 11-13; Herba solani photeinocarpi 10-11.
More preferably, Folium Bambusae 14; Rabdosia rubescens 12; Herba Cardui Crispi 10; Herba Ludwigiae Prostratae 11; Herba Ixeritis chinensis 11.5; Herba Moslae Soochowensis 11.5; Thatch melon 10.5; Radix Talini Paniculati 13; Ramulus Uncariae Cum Uncis 11.5; Herba goodyearae repentis 13.5; Tylophora florlbunda 10.5; Flos dolichoris 12; Herba solani photeinocarpi 10.5.
The compositions of described treatment heatstroke, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mix with crude drug, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned, dry and pulverize, decoct with water twice with step (1) (2) (3) made crude drug, it is (preferred: each decocting time is 24-32 minute that each decocting time is 20-36 minute; Be more preferably: each decocting time is 28 minutes), after filtration, merge twice gained filtrate;
(5) heat concentration step (4) gained filtrate and, to the half of original volume, obtain decoction.
The preparation method of the compositions decoction of described treatment heatstroke, the 6-8 that step (4) amount of water is boiled crude drug quality is (preferred: amount of water is 7 times of boiled crude drug quality) doubly.
The compositions of described treatment heatstroke, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mix with crude drug, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) get Folium Bambusae and Flos dolichoris to clean, pulverizes and sieves together with step (1) made crude drug after drying;
(5) step (2) (3) made crude drug is placed in marmite, add the water of boiled crude drug quality 6 times, big fire is boiled to boiling, turn little fire to decoct 24-36 minute (preferred: little fire decocts 30 minutes), after filtration, collect filtrate, step (4) made medicated powder is added in filtrate, heating is concentrated into clear paste, obtains unguentum.
The preparation method of the compositions unguentum of described treatment heatstroke, it is (preferred: to pulverize 120-160 mesh sieve that step (4) pulverized 100-180 mesh sieve; Be more preferably: pulverized 140 mesh sieves).
The compositions of described treatment heatstroke, be made into pharmaceutically acceptable electuary, its preparation method is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mix with crude drug, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned, dry and pulverize, decoct with water twice with step (1) (2) (3) made crude drug, amount of water is 6 times of boiled crude drug quality, and each decocting time is 20-30 minute, after filtration, merges twice gained filtrate;
(5) spray drying step (4) gained filtrate, after pulverizing, makes graininess, obtains electuary.
The preparation method of the compositions electuary of described treatment heatstroke, each decocting time of step (4) is 22-28 minute (preferred: each decocting time is 25 minutes).
The compositions of described treatment heatstroke, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mix with crude drug, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned oven dry, pulverize and sieve together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, be crushed to oval tablet dosage form, obtain tablet.
The preparation method of the composition tablet of described treatment heatstroke, it is (preferred: to pulverize 100-120 mesh sieve that step (4) pulverized 80-140 mesh sieve; Be more preferably: pulverized 110 mesh sieves).
The composite formula science for the treatment of heatstroke provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and cure rate is high, short treating period, instant effect;
2, this formula is summed up through clinical practice for many years and is formed, and has effect of clearing away heat and expelling pathogen in the exterior, expelling summer-heat and damp;
3, Chinese crude drug selected by the present invention, safety has no side effect, applied widely.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Folium Bambusae: base is former: be the leaf of grass phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle etc.Nature and flavor: sweet; Light; Cold.Gui Jing: the heart; Lung; Stomach warp.Function cures mainly: clearing heat and relieving fidgetness; To promote the production of body fluid diuresis.Main calentura excessive thirst; little Jing Epilepsy; Cough with dyspnea tells nosebleed; Oliguria with reddish urine; Erosion of the oral mucosa tongue boil.
Rabdosia rubescens: base is former: for labiate is cracked rice the herb of fork.Nature and flavor: bitter in the mouth; Sweet; Cold nature.Function cures mainly: heat-clearing and toxic substances removing; Promoting blood circulation and stopping pain.Main laryngopharynx swelling and pain; Headache due to common cold; Tracheitis; Chronic hepatitis; Rheumatic arthritis; Snake bite and insect sting.
Herba Cardui Crispi: base is former: be feverfew silk hair Herba Cardui Crispi and the herb or the root that save hair Herba Cardui Crispi.Nature and flavor: mildly bitter flavor; Cool in nature.Function cures mainly: dispel the wind; Heat clearing away; Dampness removing; Cooling blood for hemostasis; Promoting blood circulation and detumescence.Main cold cough; Have a headache dizzy; Urinary system infection; Chyluria; Leucorrhea; Jaundice; Rheumatic arthralgia; Spit blood; Epistaxis; Hematuria; Menorrhagia; Dysfunctional uterine hemorrhage; Traumatic injury; Furuncle furuncle and phyma; Swelling and pain of hemorrhoid; Burn.
Herba Ludwigiae Prostratae: base is former: be the herb of onagraceae plant Herba Ludwigiae Prostratae.Nature and flavor: bitter in the mouth; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Inducing diuresis for treating stranguria syndrome; Removing stasis to stop bleeding.Main cough due to lung-heat; Laryngopharynx swelling and pain; Conjunctival congestion and swelling pain; Damp-heat dysentery; Jaundice; Drench pain; Edema; Leukorrhagia; Spit blood; Hematuria; Discharging fresh blood stool; Furuncle swells; Scabies; Traumatic injury wound is swollen; Traumatic hemorrhage; Snakeworm, lyssodexis.
Herba Ixeritis chinensis: base is former: be herb or the root of feverfew Herba Ixeritis chinensis.Nature and flavor: bitter in the mouth; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Detumescence and apocenosis; Cooling blood for hemostasis.Main intestinal carbuncle; Lung abscess; Cough due to lung-heat; Intestinal is scorching; Dysentery disease; Cholecystitis; Pelvic inflammatory disease; Furuncle toxic swelling; Eczema scrotum; Spit blood; Epistaxis; Metrorrhagia; Traumatic injury.
Herba Moslae Soochowensis: base is former: be the herb of labiate Suzhou shepherd's purse ramie.Nature and flavor: acrid in the mouth; Warm in nature.Gui Jing: return lung; Stomach warp.Function cures mainly: induce sweat; Drive away summer heat; Regulating QI to relieve pain.Main flu; Heatstroke; Eruptive disease; Peratodynia; Laryngopharynx swelling and pain; Furuncle; Centipete bite.
Thatch melon: base is former: be the tuber of cucurbitaceous plant thatch melon.Nature and flavor: sweet in the mouth; Bitter; Micro-puckery; Cold in nature poisonous.Gui Jing: return lung; Liver; Spleen channel.Function cures mainly: heat-clearing and toxic substances removing; Blood stasis-eliminating and stagnation-dissipating; Reduce phlegm dampness removing.Main sore and toxic; Boiling hot fire is puted in order; Lung abscess is coughed; Laryngopharynx swelling and pain; Edema abdominal distention; Diarrhoea; Dysentery; Alcoholic jaundice; Eczema; Rheumatic arthralgia.
Radix Talini Paniculati: base is former: be the root of portulacaceous plant smoke tree orchid.Nature and flavor: sweet; Light; Property is put down.Gui Jing: spleen; Lung; Kidney channel.Function cures mainly: qi invigorating and lung moistening; Cough-relieving; Regulating menstruation.Main deficiency of vital energy sesame is tired; Lack of appetite; Have loose bowels; Pulmonary tuberculosis hemoptysis; Dizzy; Hectic fever; Night sweat; Spontaneous perspiration; Menoxenia; Leukorrhagia, paturient's hypogalactia.
Ramulus Uncariae Cum Uncis: nature and flavor with return through: sweet, cool.Return liver, pericardium channel.There is dispelling wind and relieving convulsion, effect of heat clearing away suppressing the hyperactive liver.For liver-wind stirring up internally, infantile convulsion is twitched, and hyperpyrexia convulsion, dysphoric cold, children's's night crying due to fright in infant, pre-eclampsia, has a headache dizzy.
Herba goodyearae repentis: base is former: be the herb of the large Herba goodyearae repentis of orchid, little Herba goodyearae repentis, greatly piebaldism orchid or floss tikka aspidistra.Nature and flavor: sweet; Pungent; Flat.Function cures mainly: nourishing the lung to arrest cough; Tonify Qi of the kidney; Promoting flow of QI and blood; Subduing swelling and detoxicating.Main pulmonary tuberculosis cough; Tracheitis; Dizzy weak; Neurasthenia; Sexual impotence; Traumatic injury; Arthralgia; Laryngopharynx swelling and pain; Acute mastitis; Furuncle; Scrofula; Venom.
Tylophora florlbunda: base is former: be the root of Luo Ru section Tylophora plant tylophora florlbunda, perennial winding liana, has milk; Root hair shape, faint yellow; Be used as medicine with root.Composition: containing tylophorine, 2,3,5,6-tetramethoxyphenanthro[9,10:6',7', tylophorinine alkali.The property of medicine: pungent, temperature, slightly poisonous.Function cures mainly: dispelling pathogenic wind and eliminating phlegm, promoting blood circulation and stopping pain, removing toxic substances and promoting subsidence of swelling.Cure mainly cough with asthma abundant expectoration, diphtheria, infantile convulsion, rheumatic arthralgia, traumatic injury, fracture, venom, carbuncle furuncle, acute conjunctivitis, stomatitis, edema, hepatosplenomegaly.
Flos dolichoris: base is former: be the flower of leguminous plant Seem Lablab Album.Nature and flavor: flat; Sweet light; Nontoxic.Gui Jing: spleen; Stomach; Large intestine channel.Function cures mainly: expelling summer-heat and damp, and middle spleen invigorating.Main summer Sunstroke wets, and heating, has loose bowels, dysentery, leucorrhea with red and white discharge, and traumatic injury wound is swollen.
Herba solani photeinocarpi: base is former: be the herb of plant of Solanaceae S. photeinocarpum.Nature and flavor: mildly bitter flavor; Cold in nature.Function cures mainly: heat-clearing and toxic substances removing; Inducing diuresis and reducing edema.Main hypertension; Dysentery; Pyretic stranguria; Conjunctival congestion; Laryngopharynx swelling and pain; Furuncle furuncle and phyma.
embodiment 1the compositions for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: 11 parts, Folium Bambusae, Rabdosia rubescens 9 parts, Herba Cardui Crispi 7 parts, Herba Ludwigiae Prostratae 8 parts, Herba Ixeritis chinensis 7 parts, Herba Moslae Soochowensis 9 parts, 6 parts, thatch melon, Radix Talini Paniculati 10 parts, Ramulus Uncariae Cum Uncis 8 parts, Herba goodyearae repentis 11 parts, tylophora florlbunda 8 parts, Flos dolichoris 10 parts, Herba solani photeinocarpi 9 parts.The preparation method of the compositions decoction of above-mentioned treatment heatstroke is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mixes with crude drug, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned, dry and pulverize, decoct with water twice with step (1) (2) (3) made crude drug, amount of water is 7 times of boiled crude drug quality, and each decocting time is 28 minutes, after filtration, merges twice gained filtrate;
(5) heat concentration step (4) gained filtrate and, to the half of original volume, obtain decoction.
embodiment 2the compositions for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: 17 parts, Folium Bambusae, Rabdosia rubescens 15 parts, Herba Cardui Crispi 13 parts, Herba Ludwigiae Prostratae 14 parts, Herba Ixeritis chinensis 16 parts, Herba Moslae Soochowensis 14 parts, 15 parts, thatch melon, Radix Talini Paniculati 16 parts, Ramulus Uncariae Cum Uncis 15 parts, Herba goodyearae repentis 16 parts, tylophora florlbunda 13 parts, Flos dolichoris 14 parts, Herba solani photeinocarpi 12 parts.The preparation method of the compositions unguentum of above-mentioned treatment heatstroke is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mixes with crude drug, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) get Folium Bambusae and Flos dolichoris to clean, after drying, pulverizes 140 mesh sieves together with step (1) made crude drug;
(5) be placed in marmite by step (2) (3) made crude drug, add the water of boiled crude drug quality 6 times, big fire is boiled to boiling, turn little fire to decoct 30 minutes, after filtration, collect filtrate, be added in filtrate by step (4) made medicated powder, heating is concentrated into clear paste, obtains unguentum.
Model case: xxx, women, 25 years old.Main suit: pale, perspiration uncomfortable in chest, absent minded; Medical history: patient goes out work, prominent sense is thirsty, dizzy, myasthenia of limbs, and perspire serious, body temperature of testing oneself reaches 38.1 DEG C, through diagnosis, is diagnosed as heatstroke.
Taking this example gained unguentum, each 6-10g, warm boiled water, one day twice, two days is a course for the treatment of, and after patient takes two hours, sensation body temperature declines to some extent, and uncomfortable disease alleviates, and take two days later, uncomfortable disease is all eliminated, and physical recovery is normal.
embodiment 3the compositions for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: 12 parts, Folium Bambusae, Rabdosia rubescens 11 parts, Herba Cardui Crispi 9 parts, Herba Ludwigiae Prostratae 10 parts, Herba Ixeritis chinensis 9 parts, Herba Moslae Soochowensis 11 parts, 8 parts, thatch melon, Radix Talini Paniculati 12 parts, Ramulus Uncariae Cum Uncis 10 parts, Herba goodyearae repentis 12 parts, tylophora florlbunda 9 parts, Flos dolichoris 11 parts, Herba solani photeinocarpi 10 parts.The preparation method of the compositions electuary of above-mentioned treatment heatstroke is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mixes with crude drug, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned, dry and pulverize, decoct with water twice with step (1) (2) (3) made crude drug, amount of water is 6 times of boiled crude drug quality, and each decocting time is 25 minutes, after filtration, merges twice gained filtrate;
(5) spray drying step (4) gained filtrate, after pulverizing, makes graininess, obtains electuary.
Model case: xxx, male, 48 years old.Medical history: when patient goes to work in the fields, prominent sense is dizzy serious, cannot normal stand, weakly feels sick, palpitating speed, and with slight symptoms of emesis, reaches 38.7 DEG C, flushed face, skin burns through take temperature, and after infusing to clinic, the state of an illness is slightly alleviated.
Recommend to take this example gained electuary, each 3-4g, warm boiled water, one day twice through people, within two days, be a course for the treatment of, after patient takes one day, the symptoms such as dizziness is weak are obviously alleviated, and continue to take a course for the treatment of, patient temperature is normal, and the mental status takes a turn for the better, and self-induction is fully recovered.
embodiment 4the compositions for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: 16 parts, Folium Bambusae, Rabdosia rubescens 13 parts, Herba Cardui Crispi 11 parts, Herba Ludwigiae Prostratae 12 parts, Herba Ixeritis chinensis 14 parts, Herba Moslae Soochowensis 12 parts, 13 parts, thatch melon, Radix Talini Paniculati 14 parts, Ramulus Uncariae Cum Uncis 13 parts, Herba goodyearae repentis 15 parts, tylophora florlbunda 12 parts, Flos dolichoris 13 parts, Herba solani photeinocarpi 11 parts.The preparation method of the composition tablet of above-mentioned treatment heatstroke is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mixes with crude drug, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned oven dry, pulverized 110 mesh sieves together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, be crushed to oval tablet dosage form, obtain tablet.
Model case: xxx, women, 56 years old.Medical history: in the recent period weather is scorching, and patient's self-induction is uncomfortable, perspires more, have the significantly uncomfortable disease such as thirsty, dizziness and tinnitus, slightly movable, sensation myasthenia of limbs, chest distress and palpitation symptoms, originally thinks it is hypertension symptom recurrence, and after taking depressor, symptom is not alleviated.
This example gained tablet is taken, each 3-4 sheet, warm boiled water, one day twice through doctor advised, within two days, be a course for the treatment of, after patient takes a course for the treatment of, uncomfortable disease obviously alleviates, and spirit and muscle power increase to some extent, after adhering to taking five days, all diseases disappear entirely, and patient fully recovers.
embodiment 5the compositions for the treatment of heatstroke, is prepared from (every part of 10g) primarily of following bulk drugs: 14 parts, Folium Bambusae, Rabdosia rubescens 12 parts, Herba Cardui Crispi 10 parts, Herba Ludwigiae Prostratae 11 parts, Herba Ixeritis chinensis 11.5 parts, Herba Moslae Soochowensis 11.5 parts, 10.5 parts, thatch melon, Radix Talini Paniculati 13 parts, Ramulus Uncariae Cum Uncis 11.5 parts, Herba goodyearae repentis 13.5 parts, tylophora florlbunda 10.5 parts, Flos dolichoris 12 parts, Herba solani photeinocarpi 10.5 parts.The preparation method of the compositions decoction of above-mentioned treatment heatstroke is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mixes with crude drug, and moistening 10 minutes, is placed in frying pan, and big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 25 minutes, take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned, dry and pulverize, decoct with water twice with step (1) (2) (3) made crude drug, amount of water is 7 times of boiled crude drug quality, and each decocting time is 28 minutes, after filtration, merges twice gained filtrate;
(5) heat concentration step (4) gained filtrate and, to the half of original volume, obtain decoction.
test example 1the clinical practice of the compositions (embodiment 5) of gained treatment heatstroke of the present invention:
Choose crowd: in January ,-2015 in February, 2014, in patient 295 example of four hospitals screening heatstrokes, age 15-65 year, 34.6 ± 1.8 years old mean age, course of disease 0.5-20 hour, wherein male patient 156 example, female patient 139 example.Inclusion criteria: all morbidity just all have headache in various degree, giddy, thirsty, hyperhidrosis, the performance such as weak, absent minded, and the symptom such as respiratory frequency and alteration in heart rate, appears in minimizing of then perspiring.
Before test, patient is divided into two groups at random, experimental group 180 example and matched group 115 routine, two groups in sex, sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 100-200ml, one day twice, warmly takes, and within two days, is a course for the treatment of; Matched group take other conventional medicines (HUOXIANGZHENGQI KOUFUYE, six and fixed in ball, the Liquor Flos Lonicerae Distillata etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptoms and sign all disappear, and blood pressure, pulse, breathing, body temperature all recover normal, and every test rating is all normal; (2) effective: clinical symptoms and sign alleviate, normally, every laboratory indexes is tending towards normal for blood pressure, pulse, breathing, temperature recovery; (3) invalid: clinical symptoms and sign are without improvement or increase the weight of.Total effective rate=(cure+effectively)/total number of cases * 100%.
Clinical effectiveness: after three days take medicine, the therapeutic outcome of two groups is as shown in table 1:
As shown in Table 1, the healing patient of experimental group is 142 examples, and cure rate is 78.9%, effective patient is 37 examples, and effective percentage is 20.6%, and total effective rate is 99.5%, and the patient that matched group is cured is 72 examples, cure rate is 62.6%, and effective patient is 31 examples, and effective percentage is 27.0%, total effective rate 89.6%, be starkly lower than the therapeutic effect of experimental group, illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.By the contrast therapy time, known products obtained therefrom instant effect of the present invention, healing time is short.
The Chinese medicine used in the present invention, the Folium Bambusae of clearing heat and relieving fidgetness, the Rabdosia rubescens of heat-clearing and toxic substances removing, the Herba Cardui Crispi of cooling blood for hemostasis, Herba Ixeritis chinensis, the Herba Ludwigiae Prostratae of inducing diuresis for treating stranguria syndrome, the Herba Moslae Soochowensis of expelling superficial pathogens and clearing away summer-heat, reduce phlegm the thatch melon of dampness removing, the Radix Talini Paniculati of qi invigorating and lung moistening, the Ramulus Uncariae Cum Uncis of dispelling wind and relieving convulsion, the Herba goodyearae repentis of tonifying Qi of the kidney, the tylophora florlbunda of dispelling pathogenic wind and eliminating phlegm, the Flos dolichoris of expelling summer-heat and damp, inducing diuresis and reducing edema Herba solani photeinocarpi, multiple medical material synergism, plays effect of clearing away heat and expelling pathogen in the exterior, expelling summer-heat and damp altogether.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. treat the compositions of heatstroke, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Folium Bambusae 11-17; Rabdosia rubescens 9-15; Herba Cardui Crispi 7-13; Herba Ludwigiae Prostratae 8-14; Herba Ixeritis chinensis 7-16; Herba Moslae Soochowensis 9-14; Thatch melon 6-15; Radix Talini Paniculati 10-16; Ramulus Uncariae Cum Uncis 8-15; Herba goodyearae repentis 11-16; Tylophora florlbunda 8-13; Flos dolichoris 10-14; Herba solani photeinocarpi 9-12.
2. the compositions for the treatment of heatstroke as claimed in claim 1, is characterized in that, Folium Bambusae 12-16; Rabdosia rubescens 11-13; Herba Cardui Crispi 9-11; Herba Ludwigiae Prostratae 10-12; Herba Ixeritis chinensis 9-14; Herba Moslae Soochowensis 11-12; Thatch melon 8-13; Radix Talini Paniculati 12-14; Ramulus Uncariae Cum Uncis 10-13; Herba goodyearae repentis 12-15; Tylophora florlbunda 9-12; Flos dolichoris 11-13; Herba solani photeinocarpi 10-11(is preferably: Folium Bambusae 14; Rabdosia rubescens 12; Herba Cardui Crispi 10; Herba Ludwigiae Prostratae 11; Herba Ixeritis chinensis 11.5; Herba Moslae Soochowensis 11.5; Thatch melon 10.5; Radix Talini Paniculati 13; Ramulus Uncariae Cum Uncis 11.5; Herba goodyearae repentis 13.5; Tylophora florlbunda 10.5; Flos dolichoris 12; Herba solani photeinocarpi 10.5).
3. the compositions of the treatment heatstroke as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mix with crude drug, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned, dry and pulverize, decoct with water twice with step (1) (2) (3) made crude drug, it is (preferred: each decocting time is 24-32 minute that each decocting time is 20-36 minute; Be more preferably: each decocting time is 28 minutes), after filtration, merge twice gained filtrate;
(5) heat concentration step (4) gained filtrate and, to the half of original volume, obtain decoction.
4. the preparation method of the compositions decoction for the treatment of heatstroke as claimed in claim 3, is characterized in that, the 6-8 that step (4) amount of water is boiled crude drug quality is (preferred: amount of water is 7 times of boiled crude drug quality) doubly.
5. the compositions of the treatment heatstroke as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mix with crude drug, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) get Folium Bambusae and Flos dolichoris to clean, pulverizes and sieves together with step (1) made crude drug after drying;
(5) step (2) (3) made crude drug is placed in marmite, add the water of boiled crude drug quality 6 times, big fire is boiled to boiling, turn little fire to decoct 24-36 minute (preferred: little fire decocts 30 minutes), after filtration, collect filtrate, step (4) made medicated powder is added in filtrate, heating is concentrated into clear paste, obtains unguentum.
6. the preparation method of the compositions unguentum for the treatment of heatstroke as claimed in claim 5, it is characterized in that, it is (preferred: to pulverize 120-160 mesh sieve that step (4) pulverized 100-180 mesh sieve; Be more preferably: pulverized 140 mesh sieves).
7. the compositions of the treatment heatstroke as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable electuary, its preparation method is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mix with crude drug, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned, dry and pulverize, decoct with water twice with step (1) (2) (3) made crude drug, amount of water is 6 times of boiled crude drug quality, and each decocting time is 20-30 minute, after filtration, merges twice gained filtrate;
(5) spray drying step (4) gained filtrate, after pulverizing, makes graininess, obtains electuary.
8. the preparation method of the compositions electuary for the treatment of heatstroke as claimed in claim 7, is characterized in that, each decocting time of step (4) is 22-28 minute (preferred: each decocting time is 25 minutes).
9. the compositions of the treatment heatstroke as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable tablet, its preparation method is:
(1) get Rabdosia rubescens, Herba Ludwigiae Prostratae, Herba Moslae Soochowensis, Herba goodyearae repentis and Herba solani photeinocarpi and clean remove impurity, mashed by Rhizoma Zingiberis Recens, thin up becomes pasty state, mix with crude drug, moistening 6-14 minute (preferred: moistening 10 minutes), is placed in frying pan, big fire stir-fries to drying, takes out, cools;
(2) get Herba Cardui Crispi, Herba Ixeritis chinensis, Ramulus Uncariae Cum Uncis and tylophora florlbunda roguing to clean, cut into chunks, be placed in steamer, Steam by water bath 20-30 minute (preferred: Steam by water bath 22-28 minute; Be more preferably: Steam by water bath 25 minutes), take out, add rice wine and mix thoroughly, slow fire is fried to dry, and taking-up cools;
(3) get thatch melon and Radix Talini Paniculati cleans remove impurity, be cut into sheet, add refined honey water and mix thoroughly, then mix with Testa Tritici, be placed in frying pan, slow fire is fried and is turned yellow to crude drug surface, and take out, sieve removes Testa Tritici;
(4) Folium Bambusae and Flos dolichoris are cleaned oven dry, pulverize and sieve together with step (1) (2) (3) made crude drug, according to the preparation method of tablet, be crushed to oval tablet dosage form, obtain tablet.
10. the preparation method of the composition tablet for the treatment of heatstroke as claimed in claim 9, it is characterized in that, it is (preferred: to pulverize 100-120 mesh sieve that step (4) pulverized 80-140 mesh sieve; Be more preferably: pulverized 110 mesh sieves).
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| CN104173793A (en) * | 2014-07-16 | 2014-12-03 | 周剑峰 | Traditional Chinese medicinal preparation for treating sunstroke |
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| Title |
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| 张艳: "重度中暑患者32例急救与护理", 《中国煤炭工业医学杂志》 * |
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