CN105288184A - Traditional Chinese medicine composition for treating depression and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating depression and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating depression. The traditional Chinese medicine composition is mainly prepared from the following raw medicinal materials in parts by mass: 6-10 parts of radix bupleuri, 9-14 parts of all grass of Gentiana apiata, 5-12 parts of dogwood, 8-13 parts of variegate ladyslipper herb, 7-12 parts of ramie flower, 9-13 parts of beechey fig leaf, 6-14 parts of Fructus Nandinae, 8-14 parts of day lily, 4-9 parts of Lotus Stamen, 6-11 parts of ortex lycii radicis, 7-13 parts of celastrus orbiculatus, 6-13 parts of chrysanthemum, 8-12 parts of folium cycas and 3-6 parts of exocarpium. The traditional Chinese medicine composition disclosed by the invention is prepared by clinical practice summarization in many years, has the effects of soothing liver-qi stagnation and clearing away the heart-fire and relieving restlessness and is obvious in curative effect.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to the Chinese medicine composition and method for making that cure mainly depression.
Background technology
Depression is a kind of mode of onset of manic depressive illness.Reduce with hypothymergasia, retardation of thinking and speech action, slow in classical symptom.Depression is a kind of common mental sickness, and main manifestations is depressed, and interest lowers, pessimistic, retardation of thinking, lack initiative, self-accusation from crime, diet, sleep poor, worry oneself to suffer from various disease, feeling that whole body many places are uncomfortable, can there is suicidal thought and behavior in severe patient.Depression is except there will be emotional symptoms, also there will be some somatizations, comprising sleep disordered (difficulty falling asleep, sleep shallow, early awakening, a kind of situation is in addition, it is fine that others thinks that he sleeps, but think that oneself is a bit not sleeping in person), weak or energy goes down, appetite declines, and (all can there is this situation in the patients with depression of 70%, light showing as there is not appetite, serious symptom shows as loses appetite), sexual hypofunction (women can occur amenorrhea during depression), weight loss, constipation, the non-specific somatizations such as overall pain is uncomfortable.
Publication No. CN104435463A(application number 201410388370.7) Chinese patent literature disclose and a kind of Chinese medicine of Cure of depression, composed of the following components: Rhizoma Acori Graminei 12-16g, Semen Platycladi 18-25g, Semen Ziziphi Spinosae 15-22g, Dens Draconis 10-15g, Radix Polygalae 18-25g, Cortex Albiziae 12-16g, refreshing side 18-22g.Publication No. CN103169889A(application number 201310128522.5) Chinese patent literature disclose a kind of Chinese medicine of Cure of depression, it is prepared from by the raw medicinal material of following weight portion: Fructus Gardeniae 8 parts, Flos Rosae Rugosae 6 parts, Xylocopa dissimilis (Lep.) 3 parts, Rhizoma phyllostachydis nigrae 6 parts, Bulbus Allii Macrostemonis 6 parts, Semen Bromi japonici 30 parts, Strobilus Abietis Fargesii 8 parts, the Radix Paeoniae Alba 10 parts, Flos lupuli (Flos Humuli Lupuli) 8 parts.Publication No. CN104983985A(application number CN104983985A) Chinese patent literature disclose a kind of Chinese medicine preparation of Cure of depression, this Chinese medicine preparation comprises 23 tastes such as Folium Perillae, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis, Plumula Nelumbinis, the Radix Astragali, Radix Polygalae, Fructus Corni, Cortex Moutan, Radix Codonopsis and the Radix Aucklandiae.
The medicine being used for the treatment of depressed person at present has a lot, and some drugs can only alleviate disease, and side effect is comparatively large, and dependency is strong, is the Chinese medicine formula providing a kind of curative effect reliable, safe and non-stimulating, need strengthens research in this respect.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the wide Chinese medicine composition curing mainly depression of safe and applicable and method for making.
Technical scheme of the present invention is:
Cure mainly the Chinese medicine composition of depression, be prepared from primarily of following bulk drugs, be mass parts: Radix Bupleuri 6-10; Herba Gentianae tsinglingensis 9-14; Fructus Corni 5-12; Herba Cyperipedii Margaritacei 8-13; Ramie flower 7-12; Caulis et Folium Fici beecheyanae 9-13; Fructus Nandinae Domesticae 6-14; Radix hemerocalis plicatae 8-14; Stamen Nelumbinis 4-9; Cortex Lycii 6-11; Celastrus orbiculatus Thunb. 7-13; Flos Chrysanthemi 6-13; Folium Cycadis siamensis 8-12; Exocarpium Citri Grandis 3-6.
Preferred version is, Radix Bupleuri 7-9; Herba Gentianae tsinglingensis 10-13; Fructus Corni 7-10; Herba Cyperipedii Margaritacei 9-12; Ramie flower 8-11; Caulis et Folium Fici beecheyanae 10-12; Fructus Nandinae Domesticae 8-12; Radix hemerocalis plicatae 10-12; Stamen Nelumbinis 5-8; Cortex Lycii 7-10; Celastrus orbiculatus Thunb. 9-11; Flos Chrysanthemi 8-11; Folium Cycadis siamensis 9-11; Exocarpium Citri Grandis 4-5.
More preferably, Radix Bupleuri 8; The Herba Gentianae tsinglingensis 11.5; Fructus Corni 8.5; Herba Cyperipedii Margaritacei 10.5; Ramie spends 9.5; Caulis et Folium Fici beecheyanae 11; Fructus Nandinae Domesticae 10; Radix hemerocalis plicatae 11; Stamen Nelumbinis 6.5; Cortex Lycii 8.5; Celastrus orbiculatus Thunb. 10; Flos Chrysanthemi 9.5; Folium Cycadis siamensis 10; Exocarpium Citri Grandis 4.5.
The preparation method of the decoction of described Chinese medicine composition, step is as follows:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 4-8 minute (preferred: moistening 6 minutes), be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening 10-20 minute thoroughly (preferably: mix moistening 12-18 minute thoroughly; Be more preferably: mix moistening thoroughly 15 minutes), take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 8-18 minute (preferably: moderate heat steams 10-16 minute; Be more preferably: moderate heat steams 13 minutes), taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, the moderate heat that adds water decocts twice, and it is (preferred: decocting time is 26-30 minute that each decocting time is 22-34 minute; Be more preferably: decocting time is 28 minutes), after filtration, merge twice gained filtrate, obtain decoction.
The preparation method of described Chinese medicine composition decoction, the 4-7 that step (5) amount of water is boiled crude drug quality is doubly (preferred: the 5-6 that amount of water is boiled crude drug quality is doubly; Be more preferably: amount of water is 5.5 times of boiled crude drug quality).
The preparation method of the unguentum of described Chinese medicine composition, step is as follows:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 4-8 minute (preferred: moistening 6 minutes), be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening 10-20 minute thoroughly (preferably: mix moistening 12-18 minute thoroughly; Be more preferably: mix moistening thoroughly 15 minutes), take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 8-18 minute (preferably: moderate heat steams 10-16 minute; Be more preferably: moderate heat steams 13 minutes), taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, add the soak by water of boiled crude drug quality 5 times, big fire is heated to boiling, and it is (preferred: continuation decocts 20-24 minute that a turn little fire continues decoction 18-26 minute; Be more preferably: continue decoction 22 minutes), collecting by filtration filtrate, heating is concentrated into thick paste, obtains unguentum.
The preparation method of described Traditional Chinese medicine composition paste, it is (preferred: heating is concentrated into the thick paste that relative density is 1.14-1.22 that step (5) heating is concentrated into the thick paste (65 DEG C) that relative density is 1.10-1.26; Be more preferably: heating is concentrated into the thick paste that relative density is 1.18).
The preparation method of the powder of described Chinese medicine composition, step is as follows:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 4-8 minute (preferred: moistening 6 minutes), be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening 10-20 minute thoroughly (preferably: mix moistening 12-18 minute thoroughly; Be more preferably: mix moistening thoroughly 15 minutes), take out, little fire dries, and chopping, pulverizes, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 8-18 minute (preferably: moderate heat steams 10-16 minute; Be more preferably: moderate heat steams 13 minutes), taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, add the soak by water of boiled crude drug quality 5 times, big fire is heated to boiling, and it is (preferred: continuation decocts 20-24 minute that a turn little fire continues decoction 18-26 minute; Be more preferably: continue decoction 22 minutes), collecting by filtration filtrate, this filtrate of spraying dry, pulverizes and sieves dry thing, obtains powder.
The preparation method of described Chinese medicine powder, it is (preferred: to pulverize 140-200 mesh sieve that step (5) pulverized 100-240 mesh sieve; Be more preferably: pulverized 170 mesh sieves).
The preparation method of the pill of described Chinese medicine composition, step is as follows:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 4-8 minute (preferred: moistening 6 minutes), be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening 10-20 minute thoroughly (preferably: mix moistening 12-18 minute thoroughly; Be more preferably: mix moistening thoroughly 15 minutes), take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 8-18 minute (preferably: moderate heat steams 10-16 minute; Be more preferably: moderate heat steams 13 minutes), taking-up is smashed to pieces, adds the soak by water twice of boiled crude drug quality 5 times, and each decocting time is 15-25 minute (preferred: each decocting time is 20 minutes), and collecting by filtration also merges twice gained filtrate;
(5) heat concentration step (4) gained filtrate to clear paste, add step (3) gained medicated powder, mixed accessories is mixed thoroughly, generally makes ball, obtains pill.
The preparation method of described Chinese medicine composition pill, it is (preferred: to pulverize 90-130 mesh sieve that step (3) pulverized 70-150 mesh sieve; Be more preferably: pulverized 110 mesh sieves).
The Traditional Chinese medicine composition formula science curing mainly depression provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, products obtained therefrom of the present invention, therapeutic effect is good, and total effective rate can up to 99.4%;
2, this formula is summed up through clinical practice for many years and is formed, and has dispersing the stagnated live-QI to relieve the stagnation of QI, the effect of the relieving restlessness that clears away heart-fire;
3, the present invention product curative effect reliable, take safety, applied widely, be worthy to be popularized.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Radix Bupleuri: nature and flavor with return through, pungent, bitter, be slightly cold.Return liver, gallbladder, lung meridian.Evacuation is had to bring down a fever, dispersing the stagnated live-QI to relieve the stagnation of QI, effect of elevate a turnable ladder yang-energy.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, uterine prolapse, proctoptosis.
The Herba Gentianae tsinglingensis: base is former: be the herb of the too white Radix Gentianae of gentianaceae plant.Nature and flavor: bitter; Property is put down.Gui Jing: liver; Large intestine; Urinary bladder channel.Function cures mainly: regulating menstruation and activating blood; Clearing away heat and promoting diuresis.Main menoxenia; Dysmenorrhea; Metrorrhagia; Leucorrhea; Dysentery is suffered from abdominal pain; Dysuria.
Fructus Corni: base is former: be the sarcocarp of Cornaceae plant Fructus Corni.Nature and flavor with return through: sour, puckery, tepor.Return liver, kidney channel.Have liver and kidney tonifying, effect of arresting collape syndrome by astringents, for dizzy ear toot, soreness of waist and knee joint, impotence and seminal emission, enuresis frequent micturition, bleeding not during menses, profuse sweating collapse, interior-heat is quenched one's thirst.
Herba Cyperipedii Margaritacei: base is former: be the herb of orchid variegated leaf lady's slipper.Nature and flavor: sweet; Tepor; Slightly poisonous.Gui Jing: lung; Kidney; Urinary bladder channel.Function cures mainly: tonifying liver improving eyesight; Promoting blood flow to regulate menstruation.Main nebula hides eyeball; Blurred vision; Nyctalopia; Rheumatic numbness; Menoxenia.
Ramie flower: base is former: be the flower of Urticaceae Section of Genus Boehmeria plant Boehmeria.The property of medicine: sweet, cold.Function cures mainly: clear away heart-fire relieving restlessness, removing heat from blood rash.Cure mainly vexed insomnia, aphtha of the mouth and tongue, measles is sent out not smooth thoroughly, rubella pruritus.
Caulis et Folium Fici beecheyanae: base is former: be stem, the leaf of moraceae plants Fructus Fici Beecheyanae.Nature and flavor: sweet; Light; Warm in nature.Gui Jing: lung; Spleen; Kidney channel.Function cures mainly: invigorating middle warmer spleen invigorating; Wind-damp dispelling; Promoting blood circulation to remove obstruction in the collateral.The main deficiency of vital energy is weak; Extremity are aching and limp; Rheumatic arthralgia; Stiffness of the muscle and joint; Traumatic injury; Amenorrhea; Galactostasis.
Fructus Nandinae Domesticae: base is former: be the fruit of Berberidaceae plant Fructus Nandinae Domesticae.Nature and flavor: sour in the mouth; Sweet; Property is put down; Poisonous.Gui Jing: lung; Liver Channel.Function cures mainly: astringing lung-QI and relieving cough; Relieving asthma.Main chronic cough; Pant; Pertussis.
Radix hemerocalis plicatae: base is former: be the herb of Capparidaceae plant Radix hemerocalis plicatae.Nature and flavor: sweet; Pungent; Temperature; Poisonous.Gui Jing: liver; Urinary bladder channel.Function cures mainly: dissipating blood stasis for subsidence of swelling, wind-expelling pain-stopping, and granulation promoting treats skin ulcer.Main treating swelling and pain by traumatic injury, impairment caused by overstrain lumbago, pathogenic QI in the body pain, headache, dysentery, and skin ulcer is swung and is festered, have sharp ears is suppurated, furious pain of itching, leucorrhea stranguria with turbid discharge.
Stamen Nelumbinis: base is former: be the stamen of nymphaeaceae plant lotus.Nature and flavor: sweet; Puckery; Flat.Gui Jing: the heart; Kidney channel.Function cures mainly: clear away heart-fire kidney tonifying; Unsmoothing the sperm and stopping bleeding.Main seminal emission; Frequent micturition; The enuresis; Leukorrhagia; Spit blood; Metrorrhagia.
Cortex Lycii: base is former: be the dry root bark of matrimony vine of solanaceae plant or lycium barbarum.Nature and flavor with return through: sweet, cold.Return lung, liver, kidney channel.Function with cure mainly: removing heat from blood except steaming, lung heat clearing pathogenic fire reducing.For deficiency of YIN hectic fever, hectic fever due to YIN-deficiency night sweat, cough due to lung-heat, spitting of blood, epistaxis, interior-heat is quenched one's thirst.
Celastrus orbiculatus Thunb.: base is former: be the rattan of Celastraceae plant Celastrus orbiculatus Thunb..Nature and flavor: bitter; Pungent; Tepor.Gui Jing: liver; Urinary bladder channel.Function cures mainly: expelling wind and removing dampness; Inducing menstruation to relieve menalgia; Promoting blood circulation and detoxication.Main rheumatic arthritis; Numb limbs and tense tendons, paralysis; Headache; Toothache; Hernia; Dysmenorrhea; Amenorrhea; Infantile convulsion; Osteopatia sprain; Dysentery; Acute filthy disease; Herpes zoster.
Flos Chrysanthemi: chemical analysis: flower and stem containing volatile oil, and have adenine, choline, stachydrine etc.Flower is again containing chrysanthemum glycoside, aminoacid, flavonoid and mcg vitamin B1.Volatile oil is mainly containing Borneolum Syntheticum, Camphora, chrysanthenone etc.Flavonoid has luteolin-7-glycoside, cosmosiin, acaciin.Still containing aminozide.Nature and flavor: sweetness and bitterness are cool.Gui Jing: enter lung, Liver Channel.Function cures mainly: dispelling wind, heat clearing away, improving eyesight, removing toxic substances.Control headache, dizzy, conjunctival congestion, irritable feverish sensation of chest and heart, furuncle, toxic swelling.
Folium Cycadis siamensis: base is former: be the leaf of Cycadaceae cycas sago cycas.The property of medicine: sweet, light, flat, mild toxicity.Enter liver stomach warp.Function cures mainly: regulating QI to relieve pain, and dissipating blood stasis stops blooding, subduing swelling and detoxicating.Cure mainly stagnation of liver-QI and stomach-QI pain, amenorrhea, spit blood, have blood in stool, dysentery, toxic swelling, traumatic hemorrhage, traumatic injury.
Exocarpium Citri Grandis: base is former: be the outside rind of the immature fruit of Rutaceae plant Citrus grandis or Fructus Citri grandis.Chemical analysis: fruit is containing naringin, naringin unit; Peel is containing citral, geraniol, linalool, phosphorus Methyl anthranilate etc.Nature and flavor: bitter; Pungent; Temperature.Gui Jing: spleen; Lung meridian.Drying dampness to eliminate phlegm; Regulate the flow of vital energy; Help digestion.Main air is trembled with fear cough with asthma abundant expectoration; Vomiting singultus; Accumulation of food in the stomach and intes tine due to indigestion; Abdominal distention.
embodiment 1cure mainly the Chinese medicine composition of depression, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Bupleuri 6 parts, the Herba Gentianae tsinglingensis 9 parts, Fructus Corni 5 parts, Herba Cyperipedii Margaritacei 8 parts, ramie spends 7 parts, Caulis et Folium Fici beecheyanae 9 parts, Fructus Nandinae Domesticae 6 parts, Radix hemerocalis plicatae 8 parts, Stamen Nelumbinis 4 parts, Cortex Lycii 6 parts, Celastrus orbiculatus Thunb. 7 parts, Flos Chrysanthemi 6 parts, Folium Cycadis siamensis 8 parts, Exocarpium Citri Grandis 3 parts.The above-mentioned preparation method curing mainly the Chinese medicine composition decoction of depression is:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 6 minutes, be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening thoroughly 15 minutes, take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 13 minutes, taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, the water moderate heat adding boiled crude drug quality 5.5 times decocts twice, and each decocting time is 28 minutes, after filtration, merges twice gained filtrate, obtains decoction.
embodiment 2cure mainly the Chinese medicine composition of depression, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Bupleuri 10 parts, the Herba Gentianae tsinglingensis 14 parts, Fructus Corni 12 parts, Herba Cyperipedii Margaritacei 13 parts, ramie spends 12 parts, Caulis et Folium Fici beecheyanae 13 parts, Fructus Nandinae Domesticae 14 parts, Radix hemerocalis plicatae 14 parts, Stamen Nelumbinis 9 parts, Cortex Lycii 11 parts, Celastrus orbiculatus Thunb. 13 parts, Flos Chrysanthemi 13 parts, Folium Cycadis siamensis 12 parts, Exocarpium Citri Grandis 6 parts.The above-mentioned preparation method curing mainly the Traditional Chinese medicine composition paste of depression is:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 6 minutes, be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening thoroughly 15 minutes, take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 13 minutes, taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, add the soak by water of boiled crude drug quality 5 times, big fire is heated to boiling, turn little fire and continue decoction 22 minutes, collecting by filtration filtrate, heating is concentrated into the thick paste (65 DEG C) that relative density is 1.18, obtains unguentum.
Model case: xxx, women, 29 years old.Medical history: patient's married life is unhappy, frequent and husband quarrels, and emotion is irritated, easily enrages, add that work is unsatisfactory recently, lassitude, can't have dinner, dizzy drowsiness, pale complexion, is in a sorrowful mood and painful once in a while, then arrives examination in hospital, is diagnosed as depression.
Taking this example gained unguentum, each 6-10g, warm boiled water, one day twice, 20 days is a course for the treatment of, after patient takes a course for the treatment of, uncomfortable disease obviously alleviates, and appetite strengthens, and adheres to taking two courses for the treatment of, and patient fully recovers, spirit takes a turn for the better, and is emotionally stable, follows up a case by regular visits in half a year, without recurrence.
embodiment 3cure mainly the Chinese medicine composition of depression, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Bupleuri 7 parts, the Herba Gentianae tsinglingensis 10 parts, Fructus Corni 7 parts, Herba Cyperipedii Margaritacei 9 parts, ramie spends 8 parts, Caulis et Folium Fici beecheyanae 10 parts, Fructus Nandinae Domesticae 8 parts, Radix hemerocalis plicatae 10 parts, Stamen Nelumbinis 5 parts, Cortex Lycii 7 parts, Celastrus orbiculatus Thunb. 9 parts, Flos Chrysanthemi 8 parts, Folium Cycadis siamensis 9 parts, Exocarpium Citri Grandis 4 parts.The above-mentioned preparation method curing mainly the Chinese medicine powder of depression is:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 6 minutes, be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening thoroughly 15 minutes, take out, little fire dries, and chopping, pulverizes, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 13 minutes, taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, add the soak by water of boiled crude drug quality 5 times, big fire is heated to boiling, turn little fire and continue decoction 22 minutes, collecting by filtration filtrate, this filtrate of spraying dry, dry thing is pulverized 170 mesh sieves, obtains powder.
Model case: xxx, male, 46 years old.Medical history: patient causes the mental status not good because divorcing, and often staying up late drinks cries bitterly, and lacks interest to life, and mood is irritated, sigh in despair, spiritlessness and weakness, slowness of thinking, cannot complete normal work or exchange with people, under the advice of friend, go to hospital admission, be diagnosed as depression.
Recommend to take this example gained powder, each 2-3g, warm boiled water through people, one day twice 20 days is a course for the treatment of, after patient takes a course for the treatment of, symptom alleviates, and after taking two courses for the treatment of, uncomfortable disease obviously alleviates, can exchange with people, adhere to taking three courses for the treatment of, patient mental recovers normal, is engaged in normal work, follow up a case by regular visits to 1 year, the state of an illness does not recur.
embodiment 4cure mainly the Chinese medicine composition of depression, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Bupleuri 9 parts, the Herba Gentianae tsinglingensis 13 parts, Fructus Corni 10 parts, Herba Cyperipedii Margaritacei 12 parts, ramie spends 11 parts, Caulis et Folium Fici beecheyanae 12 parts, Fructus Nandinae Domesticae 12 parts, Radix hemerocalis plicatae 12 parts, Stamen Nelumbinis 8 parts, Cortex Lycii 10 parts, Celastrus orbiculatus Thunb. 11 parts, Flos Chrysanthemi 11 parts, Folium Cycadis siamensis 11 parts, Exocarpium Citri Grandis 5 parts.The above-mentioned preparation method curing mainly the Chinese medicine composition pill of depression is:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 6 minutes, be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening thoroughly 15 minutes, take out, little fire dries, and chopping, pulverized 110 mesh sieves, and made medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse clean, put into steamer moderate heat and steam 13 minutes, taking-up is smashed to pieces, add the soak by water twice of boiled crude drug quality 5 times, each decocting time is 20 minutes, and collecting by filtration also merges twice gained filtrate;
(5) heat concentration step (4) gained filtrate to clear paste, add step (3) gained medicated powder, mixed accessories is mixed thoroughly, generally makes ball, obtains pill.
Model case: xxx, women, 61 years old.Medical history: patient loses satellite-pair the year before, mood is low, often dejected, heart is sad and dreary, lacks the interest exchanged with stranger, and when staying alone, often a people crys, mental derangement, appetite declines, and is slow in action, fatigue and weak, then hospital admission, be diagnosed as depression, once took downern, effect is not remarkable.
Take this example gained pill, each 2-3 ball, warm boiled water, one day twice 20 days is a course for the treatment of, after patient takes a course for the treatment of, uncomfortable disease makes moderate progress, emotion improves, and adheres to taking three courses for the treatment of, and patient's muscle power strengthens, gradually with people's normal communication, after consolidating a course for the treatment of, all diseases of patient disappear entirely, recovery from illness.
embodiment 5cure mainly the Chinese medicine composition of depression, be prepared from (every part of 10g) primarily of following bulk drugs: Radix Bupleuri 8 parts, the Herba Gentianae tsinglingensis 11.5 parts, Fructus Corni 8.5 parts, Herba Cyperipedii Margaritacei 10.5 parts, ramie spends 9.5 parts, Caulis et Folium Fici beecheyanae 11 parts, Fructus Nandinae Domesticae 10 parts, Radix hemerocalis plicatae 11 parts, Stamen Nelumbinis 6.5 parts, Cortex Lycii 8.5 parts, Celastrus orbiculatus Thunb. 10 parts, Flos Chrysanthemi 9.5 parts, Folium Cycadis siamensis 10 parts, Exocarpium Citri Grandis 4.5 parts.The above-mentioned preparation method curing mainly the Chinese medicine composition decoction of depression is:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 6 minutes, be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening thoroughly 15 minutes, take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 13 minutes, taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, the water moderate heat adding boiled crude drug quality 5.5 times decocts twice, and each decocting time is 28 minutes, after filtration, merges twice gained filtrate, obtains decoction.
test example 1gained of the present invention cures mainly the clinical practice of the Chinese medicine composition (embodiment 5) of depression:
Choosing crowd: in June ,-2015 in August, 2014, according to medical case history, is patient 268 example of depression at four hospital's Screening Diagnosis, age 18-72 year, 41.6 ± 2.0 years old mean age, the course of disease 3 months-7 years, wherein male patient 125 example, female patient 143 example.All patients are all depressed through self rating depressive scale (SDS) alleged occurrence, Hamilton (HAMD) scoring of patient all >=18 points, and TCM syndrome diagnostic criteria is with reference to " new Chinese medicine guideline of clinical investigations ", primary symptom show as interest dull, worried sentimental, spiritlessness and weakness, appetite decline, time heave a deep sigh, distending pain and abdominal distention etc.; Secondary disease main manifestations is stomachache, uncomfortable in chest, diarrhoea and loose stool etc.; Tongue arteries and veins shows as that tongue fur is white, light red tongne, stringy and thready pulse or string are slow.
Before test, patient is divided into two groups at random, experimental group 160 example and matched group 108 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes products obtained therefrom of the present invention, each 250-300ml, one day twice, warmly takes, and within 20 days, is a course for the treatment of; Matched group takes other conventional medicines (Jieyu Anshen Capsules, ANSHEN BUXIN WAN, anshen yinao wan etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) cures: clinical symptoms and uncomfortable disease are all eliminated, and have good social adaptation, can carry out daily interchange, study and work etc. normally; (2) effective: clinical symptoms and uncomfortable disease are obviously improved, and social adaptation is improved significantly, and patient can carry out daily interchange, study and work etc. substantially normally; (3) invalid: clinical symptoms and uncomfortable disease are not improved.Total effective rate=cure rate+effective percentage.
Clinical effectiveness: after the taking medicine of three courses for the treatment of, the therapeutic outcome of two groups is as shown in table 1:
The healing patient of experimental group is 92 examples, and cure rate is 57.5%, and effective patient is 67 examples, and total effective rate is 99.4%; The patient that matched group is cured is 48 examples, and cure rate is 44.4%, and effective patient is 43 examples, and total effective rate 84.2%, is starkly lower than the therapeutic effect of experimental group, and illustrate that products obtained therefrom of the present invention is evident in efficacy, cure rate is high.
The Chinese medicine used in the present invention, the Radix Bupleuri of dispersing the stagnated live-QI to relieve the stagnation of QI, the Herba Gentianae tsinglingensis of regulating menstruation and activating blood, the Fructus Corni of liver and kidney tonifying, the Herba Cyperipedii Margaritacei of tonifying liver improving eyesight, the ramie flower of the relieving restlessness that clears away heart-fire, the Caulis et Folium Fici beecheyanae of invigorating middle warmer spleen invigorating, the Fructus Nandinae Domesticae of astringing lung-QI and relieving cough, the Radix hemerocalis plicatae of wind-expelling pain-stopping, the Stamen Nelumbinis of the kidney tonifying that clears away heart-fire, the Cortex Lycii of lung heat clearing pathogenic fire reducing, the Celastrus orbiculatus Thunb. of inducing menstruation to relieve menalgia, the Flos Chrysanthemi of wind and heat dispersing, the Folium Cycadis siamensis of regulating QI to relieve pain, the Exocarpium Citri Grandis of drying dampness to eliminate phlegm, all medicines share, and have effectively given play to dispersing the stagnated live-QI to relieve the stagnation of QI, the effect of the relieving restlessness that clears away heart-fire.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. cure mainly the Chinese medicine composition of depression, it is characterized in that, be prepared from primarily of following bulk drugs, be mass parts: Radix Bupleuri 6-10; Herba Gentianae tsinglingensis 9-14; Fructus Corni 5-12; Herba Cyperipedii Margaritacei 8-13; Ramie flower 7-12; Caulis et Folium Fici beecheyanae 9-13; Fructus Nandinae Domesticae 6-14; Radix hemerocalis plicatae 8-14; Stamen Nelumbinis 4-9; Cortex Lycii 6-11; Celastrus orbiculatus Thunb. 7-13; Flos Chrysanthemi 6-13; Folium Cycadis siamensis 8-12; Exocarpium Citri Grandis 3-6.
2. cure mainly the Chinese medicine composition of depression as claimed in claim 1, it is characterized in that, Radix Bupleuri 7-9; Herba Gentianae tsinglingensis 10-13; Fructus Corni 7-10; Herba Cyperipedii Margaritacei 9-12; Ramie flower 8-11; Caulis et Folium Fici beecheyanae 10-12; Fructus Nandinae Domesticae 8-12; Radix hemerocalis plicatae 10-12; Stamen Nelumbinis 5-8; Cortex Lycii 7-10; Celastrus orbiculatus Thunb. 9-11; Flos Chrysanthemi 8-11; Folium Cycadis siamensis 9-11; Exocarpium Citri Grandis 4-5(is preferably: Radix Bupleuri 8; The Herba Gentianae tsinglingensis 11.5; Fructus Corni 8.5; Herba Cyperipedii Margaritacei 10.5; Ramie spends 9.5; Caulis et Folium Fici beecheyanae 11; Fructus Nandinae Domesticae 10; Radix hemerocalis plicatae 11; Stamen Nelumbinis 6.5; Cortex Lycii 8.5; Celastrus orbiculatus Thunb. 10; Flos Chrysanthemi 9.5; Folium Cycadis siamensis 10; Exocarpium Citri Grandis 4.5).
3. the preparation method of the decoction of the Chinese medicine composition as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 4-8 minute (preferred: moistening 6 minutes), be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening 10-20 minute thoroughly (preferably: mix moistening 12-18 minute thoroughly; Be more preferably: mix moistening thoroughly 15 minutes), take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 8-18 minute (preferably: moderate heat steams 10-16 minute; Be more preferably: moderate heat steams 13 minutes), taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, the moderate heat that adds water decocts twice, and it is (preferred: decocting time is 26-30 minute that each decocting time is 22-34 minute; Be more preferably: decocting time is 28 minutes), after filtration, merge twice gained filtrate, obtain decoction.
4. the preparation method of Chinese medicine composition decoction as claimed in claim 3, is characterized in that, the 4-7 that step (5) amount of water is boiled crude drug quality is doubly (preferred: the 5-6 that amount of water is boiled crude drug quality doubly; Be more preferably: amount of water is 5.5 times of boiled crude drug quality).
5. the preparation method of the unguentum of the Chinese medicine composition as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 4-8 minute (preferred: moistening 6 minutes), be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening 10-20 minute thoroughly (preferably: mix moistening 12-18 minute thoroughly; Be more preferably: mix moistening thoroughly 15 minutes), take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 8-18 minute (preferably: moderate heat steams 10-16 minute; Be more preferably: moderate heat steams 13 minutes), taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, add the soak by water of boiled crude drug quality 5 times, big fire is heated to boiling, and it is (preferred: continuation decocts 20-24 minute that a turn little fire continues decoction 18-26 minute; Be more preferably: continue decoction 22 minutes), collecting by filtration filtrate, heating is concentrated into thick paste, obtains unguentum.
6. the preparation method of Traditional Chinese medicine composition paste as claimed in claim 5, is characterized in that, it is (preferred: heating is concentrated into the thick paste that relative density is 1.14-1.22 that step (5) heating is concentrated into the thick paste that relative density is 1.10-1.26; Be more preferably: heating is concentrated into the thick paste that relative density is 1.18).
7. the preparation method of the powder of the Chinese medicine composition as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 4-8 minute (preferred: moistening 6 minutes), be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening 10-20 minute thoroughly (preferably: mix moistening 12-18 minute thoroughly; Be more preferably: mix moistening thoroughly 15 minutes), take out, little fire dries, and chopping, pulverizes, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 8-18 minute (preferably: moderate heat steams 10-16 minute; Be more preferably: moderate heat steams 13 minutes), taking-up is smashed to pieces, loads in bag filter together with step (3) made medicated powder;
(5) step (4) gained bag filter is put into marmite, add the soak by water of boiled crude drug quality 5 times, big fire is heated to boiling, and it is (preferred: continuation decocts 20-24 minute that a turn little fire continues decoction 18-26 minute; Be more preferably: continue decoction 22 minutes), collecting by filtration filtrate, this filtrate of spraying dry, pulverizes and sieves dry thing, obtains powder.
8. the preparation method of Chinese medicine powder as claimed in claim 7, is characterized in that, it is (preferred: to pulverize 140-200 mesh sieve that step (5) pulverized 100-240 mesh sieve; Be more preferably: pulverized 170 mesh sieves).
9. the preparation method of the pill of the Chinese medicine composition as described in as arbitrary in claim 1-2, it is characterized in that, step is as follows:
(1) get Fructus Corni and Exocarpium Citri Grandis cleans remove impurity, be cut into small pieces, add refined honey and mix thoroughly, moistening 4-8 minute (preferred: moistening 6 minutes), be placed in slow fire in pot and fry to surperficial micro-Huang, after taking-up, add liquorice beverage and soak 5 minutes, pull out and dry;
(2) ramie flower, Stamen Nelumbinis, Flos Chrysanthemi and Folium Cycadis siamensis are cleaned remove impurity, get Rhizoma Zingiberis Recens block and add yellow wine squeezing extracting juice (mass ratio of Rhizoma Zingiberis Recens block and yellow wine is 1:3), mix with crude drug, be placed in parch container, moderate heat is heated to juice and is sucked, and change little fire and stir-fry to buff, taking-up cools;
(3) get the Herba Gentianae tsinglingensis, Herba Cyperipedii Margaritacei and Radix hemerocalis plicatae removing impurity, add saline and mix moistening 10-20 minute thoroughly (preferably: mix moistening 12-18 minute thoroughly; Be more preferably: mix moistening thoroughly 15 minutes), take out, little fire dries, and chopping, pulverizes and sieves, make medicated powder together with step (1) (2) made crude drug;
(4) Radix Bupleuri, Caulis et Folium Fici beecheyanae, Fructus Nandinae Domesticae, Cortex Lycii and Celastrus orbiculatus Thunb. are picked up clean impurity, add washing water of rice rinse totally, put into steamer moderate heat and steam 8-18 minute (preferably: moderate heat steams 10-16 minute; Be more preferably: moderate heat steams 13 minutes), taking-up is smashed to pieces, adds the soak by water twice of boiled crude drug quality 5 times, and each decocting time is 15-25 minute (preferred: each decocting time is 20 minutes), and collecting by filtration also merges twice gained filtrate;
(5) heat concentration step (4) gained filtrate to clear paste, add step (3) gained medicated powder, mixed accessories is mixed thoroughly, generally makes ball, obtains pill.
10. the preparation method of Chinese medicine composition pill as claimed in claim 9, is characterized in that, it is (preferred: to pulverize 90-130 mesh sieve that step (3) pulverized 70-150 mesh sieve; Be more preferably: pulverized 110 mesh sieves).
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| CN107595601A (en) * | 2017-09-30 | 2018-01-19 | 张衡 | A kind of vola meridian point massage device for treating depression |
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| CN101194982A (en) * | 2006-12-07 | 2008-06-11 | 首都医科大学宣武医院 | Antidepressive Chinese medicine composition and method of preparing the same |
| JP2008184448A (en) * | 2007-01-31 | 2008-08-14 | Iskra Ind Co Ltd | Psychotropic agent |
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| CN107595601A (en) * | 2017-09-30 | 2018-01-19 | 张衡 | A kind of vola meridian point massage device for treating depression |
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