CN105125675A - Application of medicine for treating Meniere's vertiginous syndrome - Google Patents
Application of medicine for treating Meniere's vertiginous syndrome Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating Meniere's vertiginous syndrome. The traditional Chinese medicine preparation is prepared from the following main ingredients in parts by weight: 18 to 28 parts of gypsum, 3 to 9 parts of mica, 8 to 12 parts of ledebouriella seseloides, 3 to 6 parts of scorpion, 4 to 6 parts of chilopod, 20 to 40 parts of salvia miltiorrhiza, 12 to 22 parts of red paeonia, 6 to 9 parts of earthworm, 5 to 12 parts of selfheal, 5 to 15 parts of refined peach kernel, 6 to 12 parts of notopterygium roots, 6 to 12 parts of chrysanthemum indicum, 6 to 16 parts of angelica dahurica, 5 to 15 parts of uncaria, 6 to 15 parts of securinega suffruticosa, 12 to 22 parts of stir-baked semen ziziphi spinosae, 6 to 9 parts of dogbane, 8 to 16 parts of tuckahoe, 25 to 35 parts of motherwort, 10 to 20 parts of trumpetweed, 12 to 28 parts of indigo, 6 to 10 parts of amber and 6 to 10 parts of cornu saigae. The traditional Chinese medicine composition provided by the invention has the advantages that a recipe is scientific; the preparation method of each preparation is simple; the taking of an obtained product is convenient.
Description
divisional application, original applying number 2014104441268, applying date 2014.09.03, the dizzy syndrome medicament of title Meniere's and method for making.
Technical field
The invention discloses a kind of Chinese medicine preparation, especially treat Chinese medicine preparation of the dizzy syndrome of Meniere's and preparation method thereof.Belong to traditional Chinese medicine field.
Background technology
Menieres disease, also known as hydrolabyrinth, is the membranous labyrinth generation hydrops due to internal ear, so that occurs the disease of distending pain symptom in episodic vertigo, tinnitus, deafness, head.Menieres disease is common in middle age, and the initial stage mostly is one-sided, and along with the development of the state of an illness, the patient of 9-14% can develop into bilateral.Main manifestations is distending pain in dizzy, tinnitus, deafness, head clinically, and occurs the vegetative nerve symptom such as nystagmus, dysequilibrium, Nausea and vomiting, the rhythm of the heart are slack-off, blood pressure drops, pale complexion.Its dizzy in sudden rotations time, feel self or the rotation of object around, but sanity.Recovery gradually after outbreak a few hours or a couple of days, several weeks or several years outbreak are once.Tinnitus mostly is bass, just can occur, increase the weight of during onset of vertigo before dizzy.Deafness is seldom felt in early days, just feels deaf after outbreak for several times.The factors such as the generation of Menieres disease and allergy, endocrine regulation, viral infection, anxious state of mind are relevant, wherein first-elected emotional factor.Its symptom often makes patient's emotion more unstable, therefore easily forms vicious cycle.
Menieres disease can be divided into eight types, and typing has great importance to Diagnosis and Treat.1, plain edition, the symptom such as dizzy, tinnitus, Nausea and vomiting, perspiration occurs, also known as common type simultaneously.2, starting tinnitus type, before tinnitus occurs in other symptom, several months, several years several weeks.3, tinnitus type is weighed: tinnitus performance is heavy.Tinnitus there occurs, dizzy easy outbreak, and dizzy performance weight, tinnitus also weighs.Dizzy treatment has been got well, and tinnitus is not good, dizzyly must recur.4, without tinnitus type, onset of vertigo more than 5 times, without tinnitus, claims without tinnitus type.5, sudden deafness type, in onset of vertigo process, because pressure is especially big, Mo Shu breaks on road, occurs deaf suddenly.Deaf many-side, also have bilateral alternately generation.Deaf early treatment is satisfactory for result.6, delay vertiginous type, undulatory property, nerve, Progressive symmetric erythrokeratodermia tinnitus, auditory dysesthesia, (short time does not occur dizzy) plural number even just occurs dizzy in 20 years at year.7, hide tinnitus type, patient's appearance does not have tinnitus, but in ear has the sensation of blocking, vexed swollen, sultry, pruritus, hypodynia, and this is a kind of hiding without tinnitus type Menieres disease.8, dizzy state type, show effect more than three times in one month, patient is in dizzy state, claims dizzy state type, also known as heavy type.Owing to differing to its cause of disease argument, so Therapeutic Method is also many clinically.Menieres disease available drugs or operative treatment, this disease is not treated and can be disappeared yet sometimes, but may badly influence the life of patient so that have to operate to destroy internal ear structures yet.
Publication number CN102225160A(application number 201110160255.0) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of Menieres disease, described Chinese medicine preparation is formed by the Chinese drug preparation of following weight: Herba Agrimoniae 1-10 part, Semen Cassiae 1-5 part, Radix Salviae Miltiorrhizae 0-8 part, Poria 0-6 part, Rhizoma Gastrodiae 0-4 part and Rhizoma Atractylodis Macrocephalae 0-3 part.Publication number CN102671052A(application number 201210163736.1) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of Menieres disease,, formulated by capital Rhizoma Pinelliae 6-12 weight portion, Cortex Magnoliae Officinalis 3-10 weight portion, Pericarpium Citri Reticulatae 3-15 weight portion, Poria 10-25 weight portion, Semen Coicis 10-25 weight portion, Herba Pogostemonis 10-15 weight portion, Herba Eupatorii 10-20 weight portion, Rhizoma Alismatis 10-16 weight portion, Rhizoma Gastrodiae 10-20 weight portion.Publication number CN1634516A(application number 200410097187.8) Chinese patent literature disclose a kind of pharmaceutical composition for the treatment of Menieres disease and preparation method thereof, said composition is by Radix Angelicae Pubescentis, egg, vitamin B
6, the Radix Angelicae Dahuricae, Rhizoma Chuanxiong and Rhizoma Gastrodiae powder composition.
In a word, Chinese medicine achieves certain effect in treatment primary disease, but also there are some problems, and Menieres disease controls pathogenic factor not clearly now, Therapeutic Method disunity, and treatment by Chinese herbs is main mainly with alleviation, so traditional Chinese medical science effect need to strengthen.
Summary of the invention
Not enough for prior art, the object of this invention is to provide a kind of Chinese medicine preparation for the treatment of the dizzy syndrome of Meniere's, there is feature simple to operate, evident in efficacy, and it adopts comparatively common Chinese crude drug with low cost, without financial burden.
Technical scheme of the present invention is:
The dizzy syndrome medicament of Meniere's, the main raw material(s) taking off row weight proportion is prepared from: Gypsum Fibrosum 18-28; Muscovitum 3-9; Radix Saposhnikoviae 8-12; Scorpio 3-6; Scolopendra 4-6; Radix Salviae Miltiorrhizae 20-40; Radix Paeoniae Rubra 12-22; Pheretima 6-9; Spica Prunellae 5-12; Semen Persicae 5-15 processed; Rhizoma Et Radix Notopterygii 6-12; Herba Dendranthematis indici 6-12; Radix Angelicae Dahuricae 6-16; Ramulus Uncariae Cum Uncis 5-15; Cacumen Securinegae Suffruticosae 6-15; Semen Ziziphi Spinosae (parched) 12-22; Herba Apocyni veneti 6-9; Poria 8-16; Herba Leonuri 25-35; Herba Lycopi 10-20; Indigo Naturalis 12-28; Succinum 6-10; Cornu Saigae Tataricae 6-10.
Preferred version is: Gypsum Fibrosum 22-24; Muscovitum 5-7; Radix Saposhnikoviae 10-12; Scorpio 4-6; Scolopendra 5-6; Radix Salviae Miltiorrhizae 25-35; Radix Paeoniae Rubra 15-19; Pheretima 7-8; Spica Prunellae 7-9; Semen Persicae 8-12 processed; Rhizoma Et Radix Notopterygii 8-10; Herba Dendranthematis indici 8-10; Radix Angelicae Dahuricae 10-13; Ramulus Uncariae Cum Uncis 8-12; Cacumen Securinegae Suffruticosae 9-11; Semen Ziziphi Spinosae (parched) 15-19; Herba Apocyni veneti 7-8; Poria 11-13; Herba Leonuri 28-32; Herba Lycopi 14-16; Indigo Naturalis 18-22; Succinum 7-9; Cornu Saigae Tataricae 7-9.
Be more preferably: Gypsum Fibrosum 23, Muscovitum 6, Radix Saposhnikoviae 10, Scorpio 4.5, Scolopendra 5, Radix Salviae Miltiorrhizae 30, Radix Paeoniae Rubra 17, Pheretima 7.5, Spica Prunellae 8.5, Semen Persicae 10 processed, Rhizoma Et Radix Notopterygii 9, Herba Dendranthematis indici 18, the Radix Angelicae Dahuricae 11, Ramulus Uncariae Cum Uncis 10, Cacumen Securinegae Suffruticosae 10.5, Semen Ziziphi Spinosae (parched) 17, Herba Apocyni veneti 7.5, Poria 12, Herba Leonuri 15, Herba Lycopi 15, Indigo Naturalis 20, succinum 8, Cornu Saigae Tataricae 8.
Present invention also offers and this Chinese medicine preparation is made pharmaceutically acceptable decoction, powder and pill.
The preparation method of described decoction is as follows:
1. by Scorpio, Scolopendra, Indigo Naturalis and succinum grind into powder, for subsequent use after crossing 70-100 mesh sieve (preferably 85 orders) roguing;
2. Gypsum Fibrosum, Muscovitum and Cornu Saigae Tataricae are put into marmite, intense fire forging, to being popular in, then dropping in vinegar liquid and soaks 3-5 minute (preferably 4 minutes);
3. continue to add water toward marmite in, big fire decocts to boiling, and then little fire slowly decocts 50-90(preferably 70) minute, after filtration medicinal liquid, medicinal residues add water and repeat to decoct, and the rear slow fire of boiling boils 30-50(preferably 40) minute, mix twice gained medicinal liquid;
4. by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Pheretima, Spica Prunellae, Semen Persicae processed, Rhizoma Et Radix Notopterygii, Herba Dendranthematis indici, the Radix Angelicae Dahuricae, Ramulus Uncariae Cum Uncis, Cacumen Securinegae Suffruticosae, Semen Ziziphi Spinosae (parched), Herba Apocyni veneti, Poria, Herba Leonuri, Herba Lycopi, be cut into strip, be placed in marmite to add water and do not have medical material 3 centimetres immersion, time is 40-60 minute (preferably 50), and then intense fire is fried open, and turns slow fire boiling 20-30 minute (being preferably 25), leach medicinal liquid, medicinal residues add water and continue to decoct, and after boiling, slow fire boils 15-20 minute (being preferably 18), mixes twice medicinal liquid;
5. by above-mentioned gained liquid medicine mixing, and with step 1. medicated powder mix, sterile packaged obtains the decoction of Chinese medicine composition.
The preparation method of described decoction, step 2. in the amount of vinegar liquid be as the criterion not have medical material.
The preparation method of described powder is:
1. Scorpio, Scolopendra, Cacumen Securinegae Suffruticosae are put into marmite, slow fire fries ten minutes, and taking-up is smashed to pieces;
2. will remain the drip washing of medical material clear water, crushed after being dried becomes powder;
3. gained medicated powder is crossed 80-100 order (preferably 90 orders) sieve, mix homogeneously, and sterilizing subpackage obtains powder.
The preparation method of described pill is:
1. Scorpio, Scolopendra, Cacumen Securinegae Suffruticosae are put into marmite, slow fire fries ten minutes, and taking-up is smashed to pieces;
2. will remain the drip washing of medical material clear water, crushed after being dried becomes powder;
3. gained medicated powder is crossed 80-100 order (preferably 90 orders) sieve, mix homogeneously, add water and generally make ball;
4. medicine sieve crossed by the pill made, and selects the pill of size uniformity, encapsulates after dry sterilization.
The preparation method of described pill, the step diameter that 4. Chinese medicine sieves is that 5-10mm(is preferably 8mm)
Present invention also offers the application of described Chinese medicine preparation when preparing the medicine of the dizzy syndrome for the treatment of Meniere's.
The pharmacological effect of each crude drug is respectively:
Gypsum Fibrosum: Gypsum Fibrosum is monoclinic system mineral, main chemical compositions is calcium sulfate (CaSO
4) hydrate.Gypsum Fibrosum is natural dihydrate gypsum (CaSO both
42H
2o).Nature and flavor: pungent, sweet, are slightly cold.Attach to the lung and stomach meridians.Have clearing away heat-fire, relieving restlessness is quenched the thirst, effect of convergence granulation promoting.Cure mainly: apoplexy cold and heat, heart subinverse gas is frightened to be breathed heavily, and xerostomia scorching tongue, can not cease, hardness and fullness in the abdomen pain, evil removing ghost, puerperium incised wound.Except seasonal epidemic pathogens headache fever of the body, three burnt large heat, skin heat, stagnation of QI in the intestines and stomach, expelling pathogenic factors from muscles by diaphoresis, restlessness accompanied by ascending of QI of only quenching one's thirst, the sudden and violent gas of abdominal distention, pharynx heat of panting, also can do bath soup.Cure the wound cold headache as split.Simmer tea with Herba Alii fistulosi, pain of decaptitating.Control sky capable fanatic, wind syndrome of head revolves, stimulating milk secretion, wipes tooth benefit tooth.Except gastric heat lung-heat, loose YIN pathogen, slow spleen QI invigorating.Only Yangming Channel headache, fever with chills, day feeds hectic fever, and drinking a large amount of water due to extreme thirst, heatstroke hectic fever, has a toothache.
Muscovitum: base is former: be silicates Mica Group Minerals white mica.Composition: the main silicate containing aluminum potassium, wherein aluminium sesquioxide 38.5%, silicon dioxide 45.2%, potassium oxide 11.8%, water 4.5%.The property of medicine: sweet, temperature.GUIXIN, liver, lung meridian.Function cures mainly: calm the nerves relieving convulsion, and sore is stopped blooding, and cures mainly palpitation and insomnia, dizzy, epilepsy, chronic diarrhea, leukorrhagia, traumatic hemorrhage, eczema.
Radix Saposhnikoviae: nature and flavor: pungent, sweet, tepor.Gui Jing: return bladder, lung, spleen, Liver Channel.Effect: expelling pathogenic wind from the body surface, removing dampness to relieve pain.Cure mainly: for affection of exogenous wind-cold, headache general pain, rheumatic arthralgia.
Scorpio: nature and flavor with return through: pungent, flat; Poisonous.Return Liver Channel.There is endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, effect of dispersing pathogen accumulation.For liver-wind stirring up internally, spasm twitch, infantile convulsion, middle air port fish sticking its mouth out of the water, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Scolopendra: nature and flavor with return through: pungent, temperature; Poisonous.Return Liver Channel.There is endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, effect of dispersing pathogen accumulation.For liver-wind stirring up internally, spasm twitch, infantile convulsion, middle air port fish sticking its mouth out of the water, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula, snake bite and insect sting.
Radix Salviae Miltiorrhizae: nature and flavor are bitter, cold nature.Energy blood circulation promoting and blood stasis dispelling, removing heat from blood, calms the nerves.Enter the heart, spleen two warp.According to " book on Chinese herbal medicine is looked for the truth ": Radix Salviae Miltiorrhizae has the effect into percardium removing blood stasis with potent drugs.Modern medicine study confirms, its energy coronary artery dilator, increases coronary flow, improve myocardial ischemia, infraction and cardiac function, regulate the rhythm of the heart, and can expand peripheral blood vessel, improve microcirculation; Body's hypoxia tolerance can be improved; There is anticoagulation, promote fibrinolytic, suppress platelet aggregation, the effect of inhibition thrombosis; Can blood fat be reduced, suppress coronary atherosclerosis to be formed; The convalescent period of erythrocyte and hematochrome can be shortened, Reticulocyte is increased, the reparation organized can be promoted, accelerate the healing of fracture; Nervus centralis is had to have inhibitory action; There is antitumor action; Energy enhancing human body immunity function; Blood glucose can be reduced; Inhibitory action is had to various bacteria such as tubercule bacillus.
Radix Paeoniae Rubra: sour in the mouth, hardship, cool in nature.There is eliminating stasis to stop pain, effect of removing heat from blood detumescence, for stomachache, hypochondriac pain, discharging fresh blood stool, conjunctival congestion, carbuncle
Pheretima: nature and flavor with return through: salty, cold.Return liver, spleen, urinary bladder channel.There is heat clearing away to calm the frightened, dredging collateral, relieving asthma, effect of diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, edema oliguria.
Spica Prunellae: nature and flavor with return through: pungent, bitter, cold.Return liver, gallbladder meridian.There is purging liver-fire, improving eyesight, effect of mass dissipating and swelling eliminating.For conjunctival congestion and swelling pain, order pearl nyctalgia, has a headache dizzy, scrofula, goiter, acute mastitis, nodules of the breast, distending pain of the breast.
Semen Persicae: bitter in the mouth, sweet, property is put down, GUIXIN, liver, large intestine channel.There is effect of blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, for amenorrhea. dysmenorrhea. mass in the abdomen mass in the abdomen, injury from falling down, dryness of the intestine constipation.Concocting method is Dan Semen Persicae, gets clean Semen Persicae, and according to the peeling of Dan method, the used time smashs to pieces.
Rhizoma Et Radix Notopterygii: warm in nature, acrid in the mouth, hardship.Have that cold expelling dispels the wind, the function of removing damp and stopping pain.For anemofrigid cold, headache body pain.The pungent temperature of this product, gas is male and fall apart, delivers power strong, the heresy of main fall apart Taiyang channel ailment said due to cold or exposure and cold-damp, has cold expelling to dispel the wind, the merit of removing dampness to relieve pain.
Herba Dendranthematis indici: base is former: be root or the herb of Compositae Dendranthema Herba Dendranthematis indici or lavandulaleaf dendranthema herb.The property of medicine: bitter, acrid, cold.Return liver, heart channel.Function cures mainly: heat-clearing and toxic substances removing, improving eyesight.Cure mainly flu, dysentery, carbuncle, furuncle, conjunctival congestion and swelling pain, dizzy, scrofula, eczema.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.For inducing sweat, dispel-wind drug.There is expelling wind and removing dampness, understand things pain-stopping, effect of detumescence and apocenosis, for headache of catching a cold, nasal obstruction, nasal sinusitis.
Ramulus Uncariae Cum Uncis: nature and flavor with return through: sweet, cool.Return liver, pericardium channel.There is dispelling wind and relieving convulsion, effect of heat clearing away suppressing the hyperactive liver.For liver-wind stirring up internally, infantile convulsion is twitched, and hyperpyrexia convulsion, dysphoric cold, children's's night crying due to fright in infant, pre-eclampsia, has a headache dizzy.
Cacumen Securinegae Suffruticosae: base is former: be browse or the root of Euphorbiaceae Suffrutescent Securinega Twig platymiscium Suffrutescent Securinega Twig.Composition: Herb contains alkaloid: Securinine, Suffrutescent Securinega Twig alkali.Containing dihydrosecurinine in leaf, securinol A, B, securinol C picrate, Bie Securinine, Securinine; Also containing phenolic constituent: Herba Euphorbiae Helioscopiae tannin B and the nor-Bergeninum of 11-O-galloyl.Containing gallic acid etc. in stem.The property of medicine: pungent, bitter, tepor, slightly poisonous.Function cures mainly: expelling wind and activating blood circulation, the strong muscle of kidney tonifying.Cure mainly lumbago due to pathogenic wind-dampness, sexual impotence, dizzy, tinnitus, deaf, facial paralysis, poliomyelitis sequela.
Semen Ziziphi Spinosae: nature and flavor with return through: sweet, sour, flat.Return liver, gallbladder, heart channel.Nourish heart tonifying liver, mind tranquilizing and the heart calming, arresting sweating, the effect of promoting the production of body fluid.For restlessness of asrhenia type and insomnia, palpitation with fear dreaminess, the empty hyperhidrosis of body, Tianjin wound is thirsty.Semen Ziziphi Spinosae (parched): get clean Semen Ziziphi Spinosae, fry to heaving according to frying method, color is micro-to be deepened.Used time smashs to pieces.
Herba Apocyni veneti: base is former: be the leaf of Apocynaceae Apocynum plant Herba Apocyni veneti.Composition: leaf contains Quercetin, isoquercitrin, hyperin, Trifolin, cloud English glycosides, rutin, cianidanol, anthraquinone, and the several amino acids such as glutamic acid, alanine.The property of medicine: sweet, micro-hardship, cool.Function cures mainly: heat clearing away, and suppressing the hyperactive liver is calmed the nerves, diuretic.Cure mainly hypertension, dizzy, headache, cardiopalmus, insomnia, edema oliguria.
Poria: nature and flavor with return through: sweet, light, flat.GUIXIN, lung, spleen, kidney channel.There is promoting diuresis to eliminate damp pathogen, spleen invigorating, effect of mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Herba Leonuri (Herba Leonuri): nature and flavor with return through: bitter, pungent, be slightly cold.Return liver, pericardium, urinary bladder channel.There is promoting blood flow to regulate menstruation, inducing diuresis to remove edema, effect of heat-clearing and toxic substances removing.For menoxenia, dysmenorrhea amenorrhea, lochiorrhea, edema oliguria, sore swollen toxin.
Herba Lycopi: nature and flavor with return through: bitter, pungent, tepor.Return liver, spleen channel.There is promoting blood flow to regulate menstruation, blood stasis dispelling eliminating carbuncle, effect of inducing diuresis to remove edema.For menoxenia, amenorrhea, dysmenorrhea, postnatal blood stasis is suffered from abdominal pain, sore and toxic, edema ascites.
Indigo Naturalis: nature and flavor with return through: salty, cold.Return Liver Channel.There is heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, effect of pathogenic fire purging arresting convulsion.For maculae caused by violent heat pathogen, heat in blood tells nosebleed, chest pain hemoptysis, aphtha. mumps, sore throat, pediatric epilepsy scared.
Succinum: base is former: the resin of pinaceae plant buries in underground for ancient times, condense fossil sample material year in year out for a long time that be transformed.Composition: mainly resinous, volatile oil.Still containing succooxyabietic acid, succinoabietinolic acid, succinosilvic acid, succinoresinol, succinoabietol and succinic acid etc.Nature and flavor with return through: flat; Sweet; GUIXIN, liver, urinary bladder channel.There is tranquillizing the mind by relieving convulsion, promoting blood circulation to remove blood stasis, effect of inducing diuresis for treating stranguria syndrome.For malaise, palpitation and insomnia, infantile convulsion epilepsy, blood-stasis syndrome, stranguria, the difficulty in urination.
Cornu Saigae Tataricae: base is former: for Bovidae Saigae Tataricae belongs to the angle of animal sahilite.Composition: sahilite angle contains keratin, calcium phosphate, insoluble inorganic salt, lysine, serine, glutamic acid, phenylalanine, leucine, aspartic acid etc.The property of medicine: salty, cold.Return liver, heart channel.Function cures mainly: suppressing the hyperactive liver to relieve the wind syndrome, liver heat removing and eyesight improving, blood-cleaning detoxifying.Cure mainly liver-wind stirring up internally, infantile convulsion is twitched, the contracture of muscle arteries and veins; Headache due to hyperactivity of liver-YANG is dizzy, liver-fire conjunctival congestion and swelling pain and heat in blood hemorrhage, epidemic febrile disease sends out speckle, carbuncle sore tumefacting virus.
Chinese medicine composition scientific formula provided by the invention, the preparation method of various dosage form is simple, products obtained therefrom taking convenience, and in addition, excellent results of the present invention also shows:
1
,preparation in this prescription can keep the comprehensive therapeutic effect of each composition of crude drug, meets Chinese medical theory;
2
,this prescription mainly for meniere vertigo, Be very effective, healing time is short;
3
,this prescription preparation method is simple, easy to carry, is convenient to taking of sufferer.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
embodiment 1
The Chinese medicine preparation of the dizzy syndrome for the treatment of Meniere's, is prepared from by following bulk drugs: Gypsum Fibrosum 18g, Muscovitum 3g, Radix Saposhnikoviae 8g, Scorpio 3g, Scolopendra 4g, Radix Salviae Miltiorrhizae 20g, Radix Paeoniae Rubra 12g, Pheretima 6g, Spica Prunellae 5g, Semen Persicae 5g processed, Rhizoma Et Radix Notopterygii 6g, Herba Dendranthematis indici 6g, Radix Angelicae Dahuricae 6g, Ramulus Uncariae Cum Uncis 5g, Cacumen Securinegae Suffruticosae 6g, Semen Ziziphi Spinosae (parched) 12g, Herba Apocyni veneti 6g, Poria 8g, Herba Leonuri 25g, Herba Lycopi 10g, Indigo Naturalis 12g, succinum 6g, Cornu Saigae Tataricae 6g.The preparation method of the Chinese medicine preparation decoction of the dizzy syndrome of above-mentioned treatment Meniere's:
1. by Scorpio, Scolopendra, Indigo Naturalis and succinum grind into powder, for subsequent use after crossing 70 mesh sieve roguings;
2. Gypsum Fibrosum, Muscovitum and Cornu Saigae Tataricae are put into marmite, intense fire forging, to being popular in, then being crossed medical material and is soaked 3 minutes in input vinegar liquid;
3. continue to add water in marmite, big fire decocts to boiling, and then little fire slowly decocts 50 minutes, obtains medicinal liquid after filtration, and medicinal residues add water and repeat to decoct, and after boiling, slow fire boils 30 minutes, mixes twice gained medicinal liquid;
4. by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Pheretima, Spica Prunellae, Semen Persicae processed, Rhizoma Et Radix Notopterygii, Herba Dendranthematis indici, the Radix Angelicae Dahuricae, Ramulus Uncariae Cum Uncis, Cacumen Securinegae Suffruticosae, Semen Ziziphi Spinosae (parched), Herba Apocyni veneti, Poria, Herba Leonuri, Herba Lycopi, be cut into strip, be placed in marmite to add water and do not have medical material 3 centimetres immersion, time is 40 minutes, and then intense fire is fried open, and turns slow fire boiling 20 minutes, leach medicinal liquid, medicinal residues add water and continue to decoct, and after boiling, slow fire boils 15 minutes, mixes twice medicinal liquid;
5. by above-mentioned gained liquid medicine mixing, and with step 1. medicated powder mix, sterile packaged obtains the decoction of Chinese medicine composition.
The instructions of taking of decoction of the present invention: take every day twice (warm), each 350m1,7 days courses for the treatment of.
Model case: xxx, age: 32 years old, sex: man, before 2 years, prominent sense is acutely dizzy at home, with Nausea and vomiting, ear hummed, moves dizzy more serious a little, the treatment of doctor trained in Western medicine palliative is carried out after removing hospital diagnosis, subsequently more than a year in, vertigo symptoms repeatedly occurs, with more uncomfortable disease.Menieres disease is derived as through various diagnosis.
Taking the Chinese medicine decoction of the dizzy syndrome for the treatment of Meniere's of this example gained, each 350ml, twice daily, seven days is a course for the treatment of.After taking 7 days, the dizzy situation of patient alleviates greatly, and the mental status increases, and continues to take two courses for the treatment of, and dizziness and tinnitus phenomenon does not occur again, and other uncomfortable diseases also disappear, and follow up a case by regular visits in two months, also without recurrence.
embodiment 2
The Chinese medicine preparation of the dizzy syndrome for the treatment of Meniere's, is prepared from by following bulk drugs: Gypsum Fibrosum 28g, Muscovitum 9g, Radix Saposhnikoviae 12g, Scorpio 6g, Scolopendra 6g, Radix Salviae Miltiorrhizae 40g, Radix Paeoniae Rubra 22g, Pheretima 9g, Spica Prunellae 12g, Semen Persicae 15g processed, Rhizoma Et Radix Notopterygii 12g, Herba Dendranthematis indici 12g, Radix Angelicae Dahuricae 16g, Ramulus Uncariae Cum Uncis 15g, Cacumen Securinegae Suffruticosae 15g, Semen Ziziphi Spinosae (parched) 22g, Herba Apocyni veneti 9g, Poria 16g, Herba Leonuri 35g, Herba Lycopi 20g, Indigo Naturalis 28g, succinum 10g, Cornu Saigae Tataricae 10g.
The preparation method of the Chinese medicine preparation powder of the dizzy syndrome of above-mentioned treatment Meniere's:
1. Scorpio, Scolopendra, Cacumen Securinegae Suffruticosae are put into marmite, slow fire fries ten minutes, and taking-up is smashed to pieces;
2. will remain the drip washing of medical material clear water, crushed after being dried becomes powder;
3. above-mentioned gained medicated powder is crossed 80 mesh sieves, mix homogeneously, and sterilizing subpackage obtains powder.
Powder is made 4g/ bag.Instructions of taking: every day 2-3 time, each one bag, with warm boiled water, 7 days courses for the treatment of.
embodiment 3
The Chinese medicine preparation of the dizzy syndrome for the treatment of Meniere's, is prepared from by following bulk drugs: Gypsum Fibrosum 22g, Muscovitum 5g, Radix Saposhnikoviae 10g, Scorpio 4g, Scolopendra 5g, Radix Salviae Miltiorrhizae 25g, Radix Paeoniae Rubra 15g, Pheretima 7g, Spica Prunellae 7g, Semen Persicae 8g processed, Rhizoma Et Radix Notopterygii 8g, Herba Dendranthematis indici 8g, Radix Angelicae Dahuricae 10g, Ramulus Uncariae Cum Uncis 8g, Cacumen Securinegae Suffruticosae 9g, Semen Ziziphi Spinosae (parched) 15g, Herba Apocyni veneti 7g, Poria 11g, Herba Leonuri 28g, Herba Lycopi 14g, Indigo Naturalis 18g, succinum 7g, Cornu Saigae Tataricae 7g.
The medicine pill preparation method of the dizzy syndrome for the treatment of Meniere's is:
1. Scorpio, Scolopendra, Cacumen Securinegae Suffruticosae are put into marmite, slow fire fries ten minutes, and taking-up is smashed to pieces;
2. will remain the drip washing of medical material clear water, crushed after being dried becomes powder;
3. gained medicated powder is crossed 80 mesh sieves, mix homogeneously, add water and generally make ball;
4. diameter 5mm medicine sieve crossed by the pill made, and selects the pill of size uniformity, encapsulates after dry sterilization.
Instructions of taking: every day 2-3 time, each two balls, with warm boiled water, seven days courses for the treatment of.
Model case: xxx, the age: 40 years old, sex: female, main suit: dizzy, look thing and rotate with Nausea and vomiting one day, history of present illness: readme starts a little dizzy, symptom is comparatively light, does not pay attention to.Rear riding vehicle one hour exacerbation of symptoms, obviously look thing rotate, eye opens difficulty, nausea and vomiting repeatedly, walking can not, head swing time above-mentioned symptom more serious.Have a medical check-up: vital sign is steady, and the light tenderness of neck 5,6, the heart, lung, abdomen are showed no exception.Nervous system no abnormality seen.Suddenly look into head CT no abnormality seen.K is on the low side, AD: the dizzy syndrome of Meniere's.
Taking this example gained medicine pill, each two balls, every day three times, with warm boiled water, seven days is a course for the treatment of.After taking 14 days, dizzy phenomenon reduces, normal depending on thing, continues to take two courses for the treatment of, and without unfavorable symptoms such as nausea and vomiting, head oscillation is without other untoward reaction, and patient's self-induction is fully recovered.
embodiment 4
The Chinese medicine preparation of the dizzy syndrome for the treatment of Meniere's, is prepared from by following bulk drugs: Gypsum Fibrosum 24g, Muscovitum 7g, Radix Saposhnikoviae 12g, Scorpio 6g, Scolopendra 6g, Radix Salviae Miltiorrhizae 35g, Radix Paeoniae Rubra 19g, Pheretima 8g, Spica Prunellae 9g, Semen Persicae 12g processed, Rhizoma Et Radix Notopterygii 10g, Herba Dendranthematis indici 10g, Radix Angelicae Dahuricae 13g, Ramulus Uncariae Cum Uncis 12g, Cacumen Securinegae Suffruticosae 11g, Semen Ziziphi Spinosae (parched) 19g, Herba Apocyni veneti 8g, Poria 13g, Herba Leonuri 32g, Herba Lycopi 16g, Indigo Naturalis 22g, succinum 9g, Cornu Saigae Tataricae 9g.The preparation method of the Chinese medicine preparation decoction of the dizzy syndrome for the treatment of Meniere's:
1. by Scorpio, Scolopendra, Indigo Naturalis and succinum grind into powder, for subsequent use after crossing 100 mesh sieve roguings;
2. Gypsum Fibrosum, Muscovitum and Cornu Saigae Tataricae are put into marmite, intense fire forging, to being popular in, then being crossed medical material and is soaked 5 minutes in input vinegar liquid;
3. continue to add water in marmite, big fire decocts to boiling, and then little fire slowly decocts 90 minutes, obtains medicinal liquid after filtration, and medicinal residues add water and repeat to decoct, and after boiling, slow fire boils 50 minutes, mixes twice gained medicinal liquid;
4. by Radix Saposhnikoviae, Radix Salviae Miltiorrhizae, Radix Paeoniae Rubra, Pheretima, Spica Prunellae, Semen Persicae processed, Rhizoma Et Radix Notopterygii, Herba Dendranthematis indici, the Radix Angelicae Dahuricae, Ramulus Uncariae Cum Uncis, Cacumen Securinegae Suffruticosae, Semen Ziziphi Spinosae (parched), Herba Apocyni veneti, Poria, Herba Leonuri, Herba Lycopi, be cut into strip, be placed in marmite to add water and do not have medical material 3 centimetres immersion, time is 60 minutes, and then intense fire is fried open, and turns slow fire boiling 30 minutes, leach medicinal liquid, medicinal residues add water and continue to decoct, and after boiling, slow fire boils 20 minutes, mixes twice medicinal liquid;
5. by above-mentioned gained liquid medicine mixing, and with step 1. medicated powder mix, sterile packaged obtains the decoction of Chinese medicine composition.
The instructions of taking of decoction of the present invention: take every day twice (warm), each 350m1,7 days courses for the treatment of.
embodiment 5
The Chinese medicine preparation of the dizzy syndrome for the treatment of Meniere's, is prepared from by following bulk drugs: Gypsum Fibrosum 23g, Muscovitum 6g, Radix Saposhnikoviae 10g, Scorpio 4.5g, Scolopendra 5g, Radix Salviae Miltiorrhizae 30g, Radix Paeoniae Rubra 17g, Pheretima 7.5g, Spica Prunellae 8.5g, Semen Persicae 10g processed, Rhizoma Et Radix Notopterygii 9g, Herba Dendranthematis indici 18g, Radix Angelicae Dahuricae 11g, Ramulus Uncariae Cum Uncis 10g, Cacumen Securinegae Suffruticosae 10.5g, Semen Ziziphi Spinosae (parched) 17g, Herba Apocyni veneti 7.5g, Poria 12g, Herba Leonuri 15g, Herba Lycopi 15g, Indigo Naturalis 20g, succinum 8g, Cornu Saigae Tataricae 8g.
The preparation method of the Chinese medicine preparation powder of the dizzy syndrome for the treatment of Meniere's:
1. Scorpio, Scolopendra, Cacumen Securinegae Suffruticosae are put into marmite, slow fire fries ten minutes, and taking-up is smashed to pieces;
2. will remain the drip washing of medical material clear water, crushed after being dried becomes powder;
3. above-mentioned gained medicated powder is crossed 80 mesh sieves, mix homogeneously, and sterilizing subpackage obtains powder.
Instructions of taking: powder is made 4g/ bag.Instructions of taking: every day 2-3 time, each one bag, with warm boiled water, 7 days courses for the treatment of.
test example 1the clinical practice of the Chinese medicine preparation powder of embodiment 5 gained treatment Meniere's dizzy syndrome: in March, 2012 in JIUYUE ,-2013, choose the dizzy syndrome patients of 420 Meniere's, the range of age 30-60 year, 40.8 years old mean age, wherein women is 280 people, and male is 140 people.Be divided into two groups at random, experimental group and matched group, experimental group takes embodiment 5 products obtained therefrom, and matched group adopts other treatment method (Chinese medicine acupuncture, transfusion, sedative etc.).Using method is: take every day twice (warm), each one bag, warm boiled water, 7 days courses for the treatment of.
Curative effect situation criterion: effective: vertigo symptoms disappears, audition and vestibular function examination normally, are followed up a case by regular visits to and are not recurred for 2 years; Effective: vertigo symptoms disappears, and audition and vestibular function examination recover normal substantially, though the number of times that shows effect in 2 years reduces, symptom is slight; Invalid: vertigo symptoms slightly improves, still recurrent exerbation in 2 years, audition and vestibular function are without improvement.Result is as shown in table 1.
Table 1: take embodiment 5 product 1-65 year septicemia patients with terminal therapeutic outcome
Therapeutic effect: cure 225 examples (86.5%), effective 20 examples (7.7%), invalid 15 examples (5.8%), total effective rate 94.2%.Successful is better than matched group.
Take front and back symptom and health change as shown in table 2
Table 2:
Treat the Chinese medicine preparation of the dizzy syndrome of Meniere's in the present invention, price of medicinal material is cheap, collocation is reasonable, meets Chinese medical theory.Get Gypsum Fibrosum in side, Radix Salviae Miltiorrhizae is monarch drug, two medicines cooperatively interact, blood circulation promoting and blood stasis dispelling, slow spleen QI invigorating, improve blood microcirculation, separately have Radix Paeoniae Rubra, Herba Dendranthematis indici, Semen Ziziphi Spinosae (parched) to be minister, Radix Paeoniae Rubra removing heat from blood is subsided a swelling, Herba Dendranthematis indici heat-clearing and toxic substances removing, Semen Ziziphi Spinosae (parched) mind tranquilizing and the heart calming, add Herba Leonuri, Herba Lycopi, the assisting a ruler in governing a country of Cornu Saigae Tataricae, for the dizzy syndrome of Meniere's, there is good curative effect.Through clinical experiment, experimental group is before and after taking medicine, and unfavorable symptom is significantly improved, and total effective rate can reach 94.2%.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, within the spirit and principles in the present invention all, any amendment, replacement, improvement etc. done, all should be included within protection scope of the present invention.
Claims (5)
1. the application of the dizzy syndrome medicament of Meniere's in the dizzy syndrome for the treatment of Meniere's.
2. application according to claim 1, is characterized in that, by the medicine of dizzy for Meniere's syndrome medicament for the preparation of the dizzy syndrome for the treatment of Meniere's.
3. the application of the dizzy syndrome medicament of Meniere's when preparing the medicine of the dizzy syndrome for the treatment of Meniere's.
4. the dizzy syndrome medicament of Meniere's as described in as arbitrary in claim 1-3, it is characterized in that, the main raw material(s) taking off row weight proportion is prepared from: Gypsum Fibrosum 23, Muscovitum 6, Radix Saposhnikoviae 10, Scorpio 4.5, Scolopendra 5, Radix Salviae Miltiorrhizae 30, Radix Paeoniae Rubra 17, Pheretima 7.5, Spica Prunellae 8.5, Semen Persicae 10 processed, Rhizoma Et Radix Notopterygii 9, Herba Dendranthematis indici 18, the Radix Angelicae Dahuricae 11, Ramulus Uncariae Cum Uncis 10, Cacumen Securinegae Suffruticosae 10.5, Semen Ziziphi Spinosae (parched) 17, Herba Apocyni veneti 7.5, Poria 12, Herba Leonuri 15, Herba Lycopi 15, Indigo Naturalis 20, succinum 8, Cornu Saigae Tataricae 8.
5. the preparation method of the dizzy syndrome medicament powder of Meniere's as claimed in claim 4, it is characterized in that, step is:
1. Scorpio, Scolopendra, Cacumen Securinegae Suffruticosae are put into marmite, slow fire fries ten minutes, and taking-up is smashed to pieces;
2. will remain the drip washing of medical material clear water, crushed after being dried becomes powder;
3. above-mentioned gained medicated powder is crossed 80-100 order (preferably 90 orders) sieve, mix homogeneously, and sterilizing subpackage obtains powder.
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| CN201510612038.9A Pending CN105168458A (en) | 2014-09-03 | 2014-09-03 | Medicine composition for treating Labyrinthine vertigo syndrome |
| CN201510611613.3A Pending CN105125675A (en) | 2014-09-03 | 2014-09-03 | Application of medicine for treating Meniere's vertiginous syndrome |
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| WO2013022243A2 (en) * | 2011-08-05 | 2013-02-14 | 동국대학교 산학협력단 | Novel biphenyl derivative or a pharmaceutically acceptable salt thereof, and pharmaceutical composition for preventing or treating inflammatory diseases or autoimmune diseases comprising same as an active ingredient |
| CN103784851A (en) * | 2014-02-16 | 2014-05-14 | 董娟 | Traditional Chinese medicinal preparation for treating Meniere's disease and preparation method thereof |
| CN103830552A (en) * | 2014-02-24 | 2014-06-04 | 王学峰 | Traditional Chinese medicine composition for treating Meniere's disease |
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| CN102225160B (en) * | 2011-06-15 | 2015-01-21 | 张明兰 | Traditional Chinese preparation for treating Menieres disease |
| CN102671052B (en) * | 2012-05-24 | 2013-07-24 | 张黎明 | Chinese medicinal composition for treating Meniere's syndrome |
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| WO2013022243A2 (en) * | 2011-08-05 | 2013-02-14 | 동국대학교 산학협력단 | Novel biphenyl derivative or a pharmaceutically acceptable salt thereof, and pharmaceutical composition for preventing or treating inflammatory diseases or autoimmune diseases comprising same as an active ingredient |
| CN103784851A (en) * | 2014-02-16 | 2014-05-14 | 董娟 | Traditional Chinese medicinal preparation for treating Meniere's disease and preparation method thereof |
| CN103830552A (en) * | 2014-02-24 | 2014-06-04 | 王学峰 | Traditional Chinese medicine composition for treating Meniere's disease |
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| 张桂英等: "清肝镇眩汤治疗梅尼埃病96例", 《河北中医》 * |
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