CN102671052B - Chinese medicinal composition for treating Meniere's syndrome - Google Patents
Chinese medicinal composition for treating Meniere's syndrome Download PDFInfo
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Abstract
The invention discloses a Chinese medicinal composition for treating Meniere's syndrome. The Chinese medicinal composition comprises (by weight parts) Rhizoma Pinelliae 6-12, Cortex Magnolia Officinalis 3-10, Pericarpium Citri Tangerinae 3-15, Poria 10-25, Semen Coicis 10-25, Herba Agastaches 10-15, Herba Eupatorii 10-20, Alismatis Rhizoma 10-16, and Rhizoma Gastrodiae 10-20. The composition can eliminate clinical symptoms of dizziness, nausea, vomit, and the like in short time, and has no recurrence.
Description
Technical field
The application relates to a kind of pharmaceutical composition for the treatment of Menieres disease, relates in particular to a kind of Chinese medicine composition for the treatment of Menieres disease.
Background technology
Menieres disease: Menieres disease claims hydrolabyrinth again, and the traditional Chinese medical science is called dizziness.Be membranous labyrinth generation hydrops, so that the disease of distending pain symptom in episodic vertigo, tinnitus, deafness, the head occurs owing to internal ear.Menieres disease is common in middle age, and the initial stage mostly is one-sided, and along with the development of the state of an illness, the patient of 9-14% can develop into bilateral.
People's ear has two kinds of functions, and the one, accept extraneous various acoustic informations; The 2nd, can play making human body keep equilibrated effect.In ear vestibule and semicircular duct are to regulate the equilibrated organ of human body, if generation edema, the people understands disequilibrium, feel on every side scenery rotate, astasia, occur that extremity are ice-cold, cold perspiration, feel bad at heart, blood pressure is low, can not feed, symptoms such as nausea and vomiting, tinnitus, auditory dysesthesia, nystagmus.Carsick, seasick, airsick, in fact all be the symptom performance of Menieres disease.Before carsick, seasick, airsick, patient's in ear vestibule has just had slight edema phenomenon, in case under the influence of the environment in the external world, this cause of disease of hiding is just brought out, make this organ of equilibration dereliction of duty to have lost the function that keeps total balance of the body, symptom just shows immediately, as dizzy uncomfortable, vomiting or the like.
Menieres disease is commonly encountered diseases and frequently-occurring disease now clinically, and ascendant trend is arranged.People's living standard now improves, and overeat cold, oily diet have been hindered taste.Taste are hindered the responsibility that its transporting and transforming nutrients from foodstuff just can not normally be taken charge of in the back.The make a living source of expectorant of taste, after phlegm-damp was many, the phlegm-damp diseases caused by retention of fluid will overflow everywhere, where spreads unchecked, and where will fall ill.Menieres disease is a kind of a kind of disease of often showing effect repeatedly, and doctor trained in Western medicine can not thoroughly be treated this disease.Traditional doctor trained in Western medicine is used tranquilizer (stable, phenobarbital, promethazine, dimenhydrinate etc.), vasodilation (nicotinic acid, 654-2 hydrobromide injection, histamine phosphate, bendazol etc.), dehydrant (acetazolamide, hydrochlorothiazide etc.) and vitamins (B family, VC) treatment the earliest, and human 50% glucose Caledonia caine, vitamin B6 intravenous injection are then arranged.Because there is not etiotropic treatment, thus behind the western medical treatment, can only the respite symptom, easily recurrence has a strong impact on patient's normal work, study, life.
Summary of the invention
Treatment mechanism:
The traditional Chinese medical science thinks that the cause of disease of Menieres disease is at taste, and theory of Chinese medical science is told us, and this disease is by burnt in the phlegm-damp diseases caused by retention of fluid retardance, and water is wet to spread unchecked, on disturb sun clearly, mist ear key makes dizzy, the vomiting of people." the spleen being adverse to dampness " " the spleen being the source of producing phlegm ".So the traditional Chinese medical science will be from appetite promoting and the spleen strengthening, eliminating phlegm and removing dampness, diuresis, dispel the wind, preventing or arresting vomiting, calmness is main, the traditional Chinese medical science has the theory of " dizziness must be caused by phlegm is dizzy, calm do not do dizzy ".The edema of in ear (phlegm-damp) has been eliminated; Wind is exactly flu, and flu has been eliminated dizzy will the recovery from illness.If do not set about treatment from taste, singly be diuresis, can only effectively must recur from now at that time.The traditional Chinese medical science " is tried to stop water from boiling by skimming it off and pouring it back, not as removing burning wood away under the boiler " thus, is exactly this reason.Modern medicine proves, cerebrovascular sclerosis disease belongs to the phlegm syndrome category of motherland's medical science, some is diagnosed as the patient of cerebrovascular sclerosis, also can treat recovery from illness with Chinese medicine composition of the present invention, does not just make clinography, statistical number of person.
Menieres disease mainly is that the in ear organ of equilibration has produced edema, how just can be caused by slight flu, and all scenery were all uneven around the patient felt, all rocking or rotating.As long as the water conservancy in the ear is come out, the wet and flu in the taste to be removed, patient's spleen and stomach function just can be normal, and the source of falling ill has been cured, and could guarantee can not recur from now on, the treatment mechanism of Here it is Chinese medicine composition of the present invention.Basic side's medicine that the present invention treats Menieres disease is: the capital Rhizoma Pinelliae, Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae, Poria, Semen Coicis, Herba Pogostemonis, Herba Eupatorii, Rhizoma Alismatis, Rhizoma Gastrodiae.
Release the side: the capital Rhizoma Pinelliae: nature and flavor suffering, temperature.Go into lung, spleen, stomach three warps.Cure mainly: drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Control the damp-phlegm cold drink, vomiting, regurgitation, cough with asthma abundant expectoration, chest and diaphragm distension, syncope due to accumulation of phlegm headache, dizzy sleeplessness.Phlegm retention vertigo and palpitation, accumulation of phlegm are dizzy, vomiting regurgitation, breast gastral cavity painful abdominal mass are vexed.Dampness, reduce phlegm, preventing or arresting vomiting, a good appetite suddenly appearing in a serious disease Jiao's phlegm-damp, diseases caused by retention of fluid, the phlegm-damp fluid-retention overflowing also can be eradicated to other organ.
Cortex Magnoliae Officinalis: nature and flavor suffering, hardship, temperature, go into spleen channel.Cure mainly: have circulation of qi promoting spleen invigorating, stopping nausea and vomiting by lowering the adverse flow of QI, alleviating distention in middle-JIAO to regulate the flow of vital energy, have the reinforcement the intestines and stomach to wriggle
Moving merit has only the function of taste has been strengthened, and taste are just understood operate as normal, wets and just can not continue to spread.Be applicable to spleen
So Cortex Magnoliae Officinalis was applicable to distension and fullness in the abdomen due to gastric qi was stagnant, the loose stool approaches and reaches expectorant, the stagnant diseases such as cough with copious phlegm of wet heap soil or fertilizer over and around the roots greatly, and is better than the Rhizoma Atractylodis Macrocephalae,
Can discharge wet better faster.
Pericarpium Citri Reticulatae: the reason spleen is good for the stomach, and the dry spleen of dispelling is wet, double reduce phlegm wet, end cold coughing.
Poria: sweet, light, flat.GUIXIN, spleen, kidney channel.Cure mainly: promoting diuresis to eliminate damp pathogen, spleen invigorating is calmed the nerves.Cure mainly edema, dysuria,
Weakness of the spleen and stomach, lack of appetite is indigestion and loss of appetite, fatigue and weakness, insufficiency of the spleen dairrhea caused by pathogenic damp, cardiopalmus, insomnia is controlled in calmness.
Semen Coicis: nature and flavor, sweet light, cold.Go into spleen, lung meridian, kidney channel.Cure mainly: spleen invigorating, tonifying the lung, dampness removing.Control have loose bowels, arthralgia chiefly caused by damp pathogen,
The contracture of muscle arteries and veins, edema, beriberi, acute appendicitis, leucorrhea.Sharp the intestines and stomach, consumer edema makes us and can eat.
Herba Pogostemonis: nature and flavor and Gui Jingxin, tepor.Return spleen, stomach, lung meridian.Cure mainly: eliminating turbid pathogen with aromatics, the appetizing preventing or arresting vomiting, delivering dispels the wind separates
Summer-heat (deliver and be exactly: diaphoresis, open sweat gland, open the epidermis pore).Be used for turbid damp obstructing in middle-JIAO, the vomiting of gastral cavity painful abdominal mass, heat-damp in summer asthenia, breast
Vexedly do not relax, cold-damp is closed summer-heat, stomachache is vomited and diarrhoea, nasosinusitis headache.
Herba Eupatorii: meridian distribution of property and flavor: suffering, flat.Return spleen, stomach, lung meridian.Cure mainly: removing dampness, expelling summer-heat, the gastral cavity vomiting and nausea that expands, sweet greasy, outer in mouthful
Affection by summer-heat is wet, hygropyrexia from the beginning of, fragrance is amusing, anorexia is not hungry, the feeling of fullness vomiting, spleen channel is damp and hot, the foul criminal of going up, merit and Herba Pogostemonis are mutually
Seemingly.
Rhizoma Alismatis: nature and flavor are sweet, and are cold.Go into bladder, kidney, spleen, three warmers, small intestinal four warps.Cure mainly: it is dizzy that phlegm retention causes, diuretic oozes
Wet, expel the heat-evil.Control dysuria, edema distension, vomiting, dysentery, phlegm retention, beriberi, gonorrhea, hematuria.Promoting diuresis to eliminate damp pathogen: use
In the oliguria of retention of water-damp in the body, can remove cards such as in ear edema, dysentery and damp and hot stranguria with turbid discharge.Control gastric and cut off the water, control Urethra astringent pain.
Rhizoma Gastrodiae: its property suffering, temperature, nontoxic.Cure mainly: epilepsy is arranged, rheumatism; Calmness, spasmolytic, analgesia, tonify deficiency, suppressing the hyperactive liver to relieve the wind syndrome
Effect.Function cures mainly the suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.It is dizzy to be used to have a headache, numb limbs and tense tendons, epilepsy clonus, tetanus.Feel dizzy,
The neurasthenia, anemofrigid-damp arthralgia, diseases such as infantile convulsion.
Above-mentioned basic Chinese medicine has eliminating turbid pathogen with aromatics, promoting diuresis to eliminate damp pathogen, and spleen invigorating is reduced phlegm, and preventing or arresting vomiting is told, the diuresis in ear edema that disappears, " delivering " dispels the wind (flu), and slight cold causes this disease easily, so will use Herba Pogostemonis, dispels the wind, is amusing, a thing dual-purpose.In addition, above-mentioned basic Chinese medicine also has calm, spasmolytic, suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion, the dizzy effect that waits of having a headache.The not useless simply medicine of this side's medicine all is the most basic medicine around the treatment Menieres disease.The side's medicine and the cause of disease are coincide, and staple together, so rouse as if small wooden raft with onset clinically.Can fundamentally eliminate phlegm-damp and in ear edema, diuresis, calmness from the source of disease.The traditional Chinese medical science dehumidifies more reliably lastingly and thoroughly than western medical treatment more comprehensively.More scientific and reasonable.
Taboo when taking medicine: raw and cold food, animal oil is eaten the food of the livings phlegm-damp that contains innage as far as possible less, has hot person to avoid dry peppery thing, the cold of prevention do.Successively decrease if any the thin weak person's dose of body, have the chronic disease patient to follow the doctor's advice, as long as taboo has not been got well and can have been recurred.If utmost point individual patient has inflammation, add antibiotic or antibiotics, the time clothes stagger.Main Therapeutic Principle is that reinforcement taste wriggling function is the taste health, wet from now on not regenerated basic assurance.This disease can not be used tonic, as the Radix Paeoniae Alba, Radix Codonopsis, and Radix Ginseng or the like, this disease is the case of a physically strong patient running a high fever, is not deficient syndrome.Can not use the Caulis Bambusae In Taenia emesis, because this moment, there was cold-damp on the Weishang more.
The invention provides a kind of Chinese medicine composition for the treatment of Menieres disease, it is characterized in that, described Chinese medicine composition is formulated by the Chinese medicine of following weight proportion:
Capital Rhizoma Pinelliae 6-12 weight portion, Cortex Magnoliae Officinalis 3-10 weight portion, Pericarpium Citri Reticulatae 3-15 weight portion, Poria 10-25 weight portion, Semen Coicis 10-25 weight portion, Herba Pogostemonis 10-15 weight portion, Herba Eupatorii 10-20 weight portion, Rhizoma Alismatis 10-16 weight portion, Rhizoma Gastrodiae 10-20 weight portion.
The preferred embodiment of the invention can be as follows:
The capital Rhizoma Pinelliae 6 grams, Cortex Magnoliae Officinalis 3 grams, Pericarpium Citri Reticulatae 3 grams, Poria 10 grams, Semen Coicis 12 grams, Herba Pogostemonis 12 grams, Herba Eupatorii 15 grams, Rhizoma Alismatis 13 grams, Rhizoma Gastrodiae 12 grams.
Or the capital Rhizoma Pinelliae 8 restrains, Cortex Magnoliae Officinalis 5 restrains, Pericarpium Citri Reticulatae 5 restrains, Poria 16 restrains, Semen Coicis 15 restrains, Herba Pogostemonis 10 restrains, Herba Eupatorii 12 restrains, Rhizoma Alismatis 15 restrains, Rhizoma Gastrodiae 12 restrains.
Or the capital Rhizoma Pinelliae 10 restrains, Cortex Magnoliae Officinalis 8 restrains, Pericarpium Citri Reticulatae 10 restrains, Poria 20 restrains, Semen Coicis 20 restrains, Herba Pogostemonis 15 restrains, Herba Eupatorii 16 restrains, Rhizoma Alismatis 12 restrains, Rhizoma Gastrodiae 18 restrains.
Chinese medicine composition of the present invention can be made any pharmacy acceptable forms by the conventional formulation method.As decoction, pill, powder, capsule, sustained-release preparation etc.
Monarch ordering: the 1. capital Rhizoma Pinelliae, Poria, Semen Coicis: be in order to remove this sick root (cause of disease), to remove the phlegm-damp in the taste, being monarch drug; 2. Cortex Magnoliae Officinalis, Pericarpium Citri Reticulatae: be the wriggling of strengthening the intestines and stomach, recover the normal function that the intestines and stomach is got rid of phlegm-damp, make taste healthy more, can thoroughly treat this disease like this, guarantee the key that do not recur to be ministerial drug.3. Rhizoma Gastrodiae, Rhizoma Alismatis: Rhizoma Alismatis can the sharp rapidly edema of removing in ear; Rhizoma Gastrodiae is calm, the indispensable medicine of the treatment vertigo.Western medical treatment should disease, and the firstth, calm, next is only diuresis, but can not thoroughly treat this disease, so this two flavors medicine is an adjuvant drug.4. Herba Pogostemonis, Herba Eupatorii: be that fragrance is amusing, wake lazy taste exactly up, allow taste work normally.The emesis that eliminates indigestion and phlegm, this patient is many with the vomiting phenomenon.The efficacy effect that medicine spleen invigorating dehumidifying above strengthening is arranged.In addition, Herba Pogostemonis has the effect except that wind (flu) concurrently, and the traditional Chinese medical science has the theory of " calm do not do dizzy ", facts have proved, Meniere disease is caused by flu often.This two flavors medicine is healthy more by spleen and stomach function, guarantees that disease does not recur, and is messenger drug.
The specific embodiment
Embodiment 1
The capital Rhizoma Pinelliae 6 grams, Cortex Magnoliae Officinalis 3 grams, Pericarpium Citri Reticulatae 3 grams, Poria 10 grams, Semen Coicis 12 grams, Herba Pogostemonis 12 grams, Herba Eupatorii 15 grams, Rhizoma Alismatis 13 grams, Rhizoma Gastrodiae 12 grams.Decoct with water, clothes were three times on 1st.
Embodiment 2
The capital Rhizoma Pinelliae 8 grams, Cortex Magnoliae Officinalis 5 grams, Pericarpium Citri Reticulatae 5 grams, Poria 16 grams, Semen Coicis 15 grams, Herba Pogostemonis 10 grams, Herba Eupatorii 12 grams, Rhizoma Alismatis 15 grams, Rhizoma Gastrodiae 12 grams.Make pill with conventional method, each clothes 3 grams of patient that body constitution is more weak, warm water delivery service, three times on the one.
Embodiment 3
The capital Rhizoma Pinelliae 10 grams, Cortex Magnoliae Officinalis 8 grams, Pericarpium Citri Reticulatae 10 grams, Poria 20 grams, Semen Coicis 20 grams, Herba Pogostemonis 15 grams, Herba Eupatorii 16 grams, Rhizoma Alismatis 12 grams, Rhizoma Gastrodiae 18 grams.Make pill with conventional method, body constitution is good, each clothes 6 grams of the patient that phlegm-damp is heavy, warm water delivery service, three times on the one.
The effect experiment
For verifying the clinical effectiveness of Chinese medicine composition of the present invention, 200 patients' treatment situation has been carried out therapeutic effect assessment and statistics, and carried out at a specified future date following up a case by regular visits to, the statistics relapse rate.Male patient 92 people in patient's sample, women patient 108 people, age 19-68 year.
The diagnostic criteria of Menieres disease: inspection visible horizon nystagmus or rotatory spontaneous eye are quivered.Tuning fork shows perceptive deafness.Get rid of the symptomatic dizzy outbreak due to the diseases such as brain organic pathological changes or arrhythmia early stage.
Curative effect judging standard: primary disease is based on dizzy, usually with retching or eat promptly and tell, and tinnitus, auditory dysesthesia, extremely severe patient just has deafly, and the aurally handicapped is rare.
Recovery from illness: dizzy, vomiting or retch, tinnitus, auditory dysesthesia four classical symptom complete obiterations;
Produce effects: dizzy, vomiting or retch, tinnitus three classical symptom complete obiterations, auditory dysesthesia is alleviated;
Take a turn for the better: dizzy, vomiting or retch, tinnitus, auditory dysesthesia four classical symptoms are all alleviated;
Invalid: dizzy, vomiting or retch, tinnitus, auditory dysesthesia four classical symptoms all do not have and change or increase the weight of.
When using traditional Chinese medicine composition for treating Menieres disease of the present invention, there is not special provision course of treatment, for most of patient, symptom just can be fully recovered in lighter general 2-3 days, just can fully recover in heavy general 15 days, therefore carried out the therapeutic effect statistics after the patient took medicine 15 days.
Therapeutic effect sees the following form:
| Type of effect | Recovery from illness | Produce effects | Take a turn for the better | Invalid |
| Number | 181 | 9 | 10 | 0 |
Take medicine the patient and to follow up a case by regular visits in 6 months and 12 months, all do not have patient's recurrence.
Concrete case: the curative effect of 3 the concrete case explanation the application Chinese medicine compositions of now giving an example: example 1: the field, the man, 45 years old, the cook, healthy, there is not chronic medical history.Suddenly do not get up one morning, feel very dizzy, where do not know oneself to be in, companion's vomiting dare not be opened eyes, and the symptom of opening eyes is just more severe, and tinnitus is not generated heat.In addition there is not other any symptom.After earlier having played the antiemetic medicine administered by injection to him, just with this side to his clothes, later symptom just progressively alleviates, and has eaten three doses, symptom with regard to elimination, has continued to take the medicine of a period of time substantially, more than 20 year so far do not recur.Example 2: Lee, the man, the street director, healthy, often dizziness is dizzy, but not serious, can have time outbreak quite serious by motorcycle, and astasia has only recumbency.Go Dazhou City central hospital treatment, made electroencephalogram, be diagnosed as the cerebrovascular sclerosis Meniere disease of holding concurrently.Lived the hospital of a period of time, used more than 7000 yuan of money, after going home, remained unchanged, sat shakiness, the whole people that is seated feels rocking, also dare not be by motorcycle.He feels that the people is thinner after having obeyed 3 doses, but sx many, just adhere to taking to him with this side, very fast symptom has just been eliminated, and does not recur once in 5 years.Example 3: Liu xx, the man, 60 years old, once be the contractor, fat, suffer from dizziness for many years, often western medical treatment is used in outbreak, though effectively, outbreak again soon.Have time outbreak severe especially, the hospital that arrives has gone to the institute of a period of time, has spent more than 5000 yuan of money, and the back of returning does not take a turn for the better.And the sitting shakiness, the retch shape is arranged, holding up the here treatment by his son, he does not have other chronic diseases, and I just treat to him with the method.Take medicine second day, symptom just had and alleviates, and adheres to later on taking this medicine, soon just thoroughly recovery from illness.So far remained dormant for many years.
Should be noted that the foregoing description only is for example of the present invention clearly is described, and be not limitation of the invention.For those of ordinary skill in the field, can also make other multi-form variation or changes on the basis of the above description.And conspicuous variation of being amplified out thus or change still are among protection scope of the present invention.
Claims (2)
1. a Chinese medicine composition for the treatment of Menieres disease is characterized in that, described Chinese medicine composition is formulated by the Chinese medicine of following weight proportion:
Capital Rhizoma Pinelliae 6-12 weight portion, Cortex Magnoliae Officinalis 3-10 weight portion, Pericarpium Citri Reticulatae 3-15 weight portion, Poria 10-25 weight portion, Semen Coicis 10-25 weight portion, Herba Pogostemonis 10-15 weight portion, Herba Eupatorii 10-20 weight portion, Rhizoma Alismatis 10-16 weight portion, Rhizoma Gastrodiae 10-20 weight portion.
2. treat the Chinese medicine composition of Menieres disease according to claim 1, described Chinese medicine composition can be made into pharmaceutically acceptable dosage form.
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Citations (2)
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| CN101732673A (en) * | 2008-11-26 | 2010-06-16 | 董玺 | Orally taken Chinese medicament for treating Meniere's disease |
| CN102363038A (en) * | 2011-11-07 | 2012-02-29 | 成都绿迪科技有限公司 | Chinese medicinal preparation for treating dizziness |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101732673A (en) * | 2008-11-26 | 2010-06-16 | 董玺 | Orally taken Chinese medicament for treating Meniere's disease |
| CN102363038A (en) * | 2011-11-07 | 2012-02-29 | 成都绿迪科技有限公司 | Chinese medicinal preparation for treating dizziness |
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| Title |
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| 《半夏白术天麻汤化裁治疗梅尼埃病100例》;郭彦军;《山西中医》;20110930;第27卷(第9期);15-16 * |
| 《梅尼矣氏病的辨证论治》;周德龙;《四川中医》;20111031;第29卷(第10期);29-30 * |
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| 郭彦军.《半夏白术天麻汤化裁治疗梅尼埃病100例》.《山西中医》.2011,第27卷(第9期),15-16. |
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