CN102225160B - Traditional Chinese preparation for treating Menieres disease - Google Patents
Traditional Chinese preparation for treating Menieres disease Download PDFInfo
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- CN102225160B CN102225160B CN201110160255.0A CN201110160255A CN102225160B CN 102225160 B CN102225160 B CN 102225160B CN 201110160255 A CN201110160255 A CN 201110160255A CN 102225160 B CN102225160 B CN 102225160B
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Abstract
The invention discloses a traditional Chinese preparation for treating Menieres disease, and the traditional Chinese preparation comprises the following components in parts by weight: 1-10 parts of hairyvein agrimony, 1-5 parts of cassia seed, 0-8 parts of the root of red-rooted salvia, 0-6 parts of Tuckahoe, 0-4 parts of rhizoma gastrodiae and 0-3 parts of bighead atractylodes rhizome. In the traditional Chinese preparation provided by the invention, the traditional Chinese medicines such as the hairyvein agrimony, the cassia seed and the other traditional Chinese medicines are compatible and are decocted into a decoction for oral administration. Thus, all the clinical symptoms such as dizziness, nausea, vomit, nystagmus and the like of patients disappear, and no patient recurs through a follow-up visit for three years. The traditional Chinese preparation for treating the Menieres disease disclosed by the invention has the advantages of simple preparation method, low expense, good treatment effects, no toxic or side effect, no recurrence and no rebound.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation for the treatment of Menieres disease
Background technology
Menieres disease is that a non-inflammatory broken out is got lost pathological changes, has dizzy, deaf, tinnitus and sometimes has the disease of the symptoms such as the vexed swollen sense of Ipsilateral in ear.Mostly be monaural morbidity, its pathogenic factor is failed to understand, men and women's sickness rate no significant difference, and patient mostly is between twenty and fifty, and within more than 60 years old, old man's sickness rate is low, in recent years also has child's case report, and the course of disease mostly is a couple of days or Zhou Yu.A lot of about the cause of disease, theory, there is no final conclusion, as allergy, dyshormonia, vitamin deficiency and Neuropsychical facto etc. cause autonomic nervous dysfunction, therefore nervus vasculairs functional disorder is made, capillary permeability increases, and cause hydrolabyrinth, membranous cochlea and sacculus expand, when stimulating cochlea and vestibular receptor, cause tinnitus, deafness, a series of clinical symptoms such as dizzy.
Menieres disease is very common in clinical, and patient is also more painful, if treatment is thorough, and somebody can leave over tinnitus, dysaudia, dizzy grade for malaise symptoms.
Generally can use tranquilizer in treatment, as stable, oryzanol, takes the circumstances into consideration to select vasodilator flunarizine, and anisodamine hydrobromide (654-2), can also apply diuretic hydrochlorothiazide, and ammonia is originally stamped one's foot fixed.If the symptom left over is tinnitus, can puerarin injection 400 milligrams be used, day a dead point, be used in conjunction 10-15 days, effect is general.
But, also do not have now a kind of effective Chinese medicine preparation to be used for the treatment of Menieres disease.
Summary of the invention
The technical issues that need to address of the present invention are just to provide a kind of Chinese medicine preparation for the treatment of Menieres disease, and it decocts into decoction by Chinese herbal medicine, convenient oral, easily absorbs, and clinical effectiveness is good, instant effect, without any side effects, strong adaptability.
For solving the problem, the present invention adopts following technical scheme:
The invention provides a kind of Chinese medicine preparation for the treatment of Menieres disease, described Chinese medicine preparation is formed by the Chinese drug preparation of following weight:
Herba Agrimoniae 1-10 part, Semen Cassiae 1-5 part, Radix Salviae Miltiorrhizae 0-8 part, Poria 0-6 part, Rhizoma Gastrodiae 0-4 part and Rhizoma Atractylodis Macrocephalae 0-3 part.
Preferably, described Chinese medicine preparation is formed by the Chinese drug preparation of following weight:
Herba Agrimoniae 1-5 part, Semen Cassiae 2-5 part, Radix Salviae Miltiorrhizae 1-4 part, Poria 3-6 part, Rhizoma Gastrodiae 0-2 part and Rhizoma Atractylodis Macrocephalae 1-3 part.
Or described Chinese medicine preparation is formed by the Chinese drug preparation of following weight:
Herba Agrimoniae 5-10 part, Semen Cassiae 1-3 part, Radix Salviae Miltiorrhizae 3-8 part, Poria 0-3 part, Rhizoma Gastrodiae 2-4 part and Rhizoma Atractylodis Macrocephalae 0-2 part.
Preferred further, described Chinese medicine preparation is formed by the Chinese drug preparation of following weight:
Herba Agrimoniae 6 parts, Semen Cassiae 3 parts, Radix Salviae Miltiorrhizae 5 parts, 4 parts, Poria, 3 parts, Rhizoma Gastrodiae and the Rhizoma Atractylodis Macrocephalae 2 parts.
Menieres disease is ear, nose, pharynx, larynx section commonly encountered diseases, and the cause of disease is unclear, existing unsatisfactory curative effect, and patient Chang Yinian recurs 3-5 time.Rely on medical history and clinical sign Accurate Diagnosis, most important to patient selection clinical treatment.
Herba Agrimoniae, Semen Cassiae are to Meniere patient clinical good effect, instant effect, without any side effects.Its meaning is that Herba Agrimoniae includes agrimonine (Agimoninc), agrimonolide (Agyunubukudc) tannin, (for Jiao's property catechol tannin do not have forefinger tan son etc.) sterol, Determination of Organic Acids 16.4%, stem, leaf is also containing sweet-scented osmanthus element-7-B-glycoside [Luteolim-7-B-Giucoside], apigenin-7-B-aqaq20yvkjs aafd (Apigenln-7-B-Glacogide) is to cardiovascular and smooth muscle shrinks function, absorptive amplitude and the tension force of gastrointestinal can be reduced, and make gastrointestinal motility stop at relaxed state, and reach extraordinary antiemetic effect.
Semen Cassiae is the dry mature seed of pulse family annual herb plant Semen Cassiae or little Semen Cassiae.Semen Cassiae, containing chrysophanol (Chiysopahol), emodin (Emodin), the large oxalic acid of aloe-emodin (Rhein), also has emodin monoglucoside, emodin anthrone, physcione (Phg-Sscioh), obtusin (Dltugin.I.e. 1.6.7 mono-or three. methoxyl group-2.8 one dicarboxyl-3-, methyl anthracene), aurantio-obtusin, Semen Cassiae pine, obtusin lactone is still containing vitamin A.Semen Cassiae bitter in the mouth, sweet and cool in nature, there is the functions such as clearing away liver-fire, wind-damp dispelling, tonifying kidney and improving eyesight.
Red sage root contains luxuriant and rich with fragrance Quinone Pigments tanshinone Ⅰ (Tanshinone I) of furo, Tanshinone II
a(Tanshinone II
a), Tanshinone II
b(Tanshinone II
b), cryptotanshinone (Cryptotonshinone), Isotanshinone I. (Isotanshinone I), Isotanshinone II (Isotanshinone II), different cryptotanshinone (Isoeryptotanshinone), miltirone (Miltirone), separately isolate tanshinol Ⅰ (Tanshinol I, C
19h
24o
3, fusing point 129 DEG C) and tanshinol II (Tanshinoi II), secondary outer still containing vitamin E, effectiveness is suitable with Fructus Hordei Germinatus.Have blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, main trusted subordinate's pathogen, borborygmus are faint as leaked water, and cold and heat gather; Only stuffy sensation with restlessness, QI invigorating.With town substitute the moon for benefit, is the routine treatment of sustaining losses in business, non-as Wen Xin, loose wind, cold and cool heat justice of falling is only mark, thus reaches the object for the treatment of both the principal and secondary aspects of a disease.
The present invention's Herba Agrimoniae, Semen Cassiae and other drug matching, decoct into decoction, oral.Every day twice, sooner or later respectively once.Make patient at short notice, dizzy, the clinical symptoms such as Nausea and vomiting and nystagmus all disappears.The clinical symptom disappearance of 95% patient after 3 days, state of an illness recovery from illness in 5-7 days.Wherein there are transference cure, the recoveries from illness such as 5% heavier patient is dizzy after 7 days, Nausea and vomiting, follow up a case by regular visits to 3 years without recurrence.
With Chinese medicine preparation of the present invention treatment Menieres disease, method is simple, and expense is low, good effect, have no side effect, without recurrence, without bounce-back.
Detailed description of the invention
Embodiment 1
Treat a Chinese medicine preparation for Menieres disease, described Chinese medicine preparation is formed by the Chinese drug preparation of following weight:
Herba Agrimoniae 30 grams, Semen Cassiae 15 grams, Radix Salviae Miltiorrhizae 25 grams, 20 grams, Poria, 15 grams, Rhizoma Gastrodiae and the Rhizoma Atractylodis Macrocephalae 10 grams.
Decoction oral is decocted in above-mentioned drug matching, every day 2 times, each 1 time sooner or later.
Embodiment 2-9 unit: gram
Herba Agrimoniae | Semen Cassiae | Radix Salviae Miltiorrhizae | Poria | Rhizoma Gastrodiae | The Rhizoma Atractylodis Macrocephalae |
Embodiment 2 | 30 | 15 | 0 | 0 | 0 | 0 |
Embodiment 3 | 30 | 15 | 25 | 0 | 0 | 0 |
Embodiment 4 | 5 | 25 | 0 | 30 | 0 | 15 |
Embodiment 5 | 50 | 5 | 40 | 0 | 20 | 0 |
Embodiment 6 | 10 | 25 | 5 | 30 | 0 | 15 |
Embodiment 7 | 25 | 10 | 20 | 15 | 10 | 5 |
Embodiment 8 | 25 | 15 | 15 | 15 | 10 | 10 |
Embodiment 9 | 50 | 5 | 40 | 0 | 20 | 0 |
Treatment example
Menieres disease patient 35 example, man 10 example, female 25 example; Age 19-70 year, middle annual morbidity is high.All patients collect medical history data all in detail, and row ear, nose, pharynx, larynx section check, some patients looks into head CT and MRI, discharge intracranial space-occupying lesion, and 35 examples all discharge in stage of attack the vertigo that other diseases causes.
Symptom:
1, the dizzy violent rotatory vertigo often broken out without any tendency, wake up with a start during Chang Congmeng sleeps or in morning time outbreak.Patient's private prosecution surrounding objects rotates around self, closes order chronognosis certainly in Space Rotating.Patient, often in compulsive position, dare not move by the tip, dynamic then vertigo symptoms can be made to increase the weight of.Sanity between period of disease.Have Nausea and vomiting during outbreak, be in a cold sweat, the symptom such as the pale and blood pressure drops of face.After a few hours or a couple of days, vertigo symptoms fades away.
2, dysaudia is listened and is stood as undulatory property sensorineural deafness, and after vertigo symptoms is alleviated in early days, audition can portion or recover completely greatly, can cause complete deafness because of repeatedly recurrent exerbation.Some patients still has high pitch hyperacusis phenomenon.
3, tinnitus is the possibility tendency before paresthesia epilepsy, and tinnitus is high-pitched tone, and possible weight differs, and before outbreak, patient may tinnitus increase the weight of, and outbreak stops, and tinnitus can be faded away.
4, homonymy head and the vexed swollen sense of in ear, most patient has this symptom, or feels top-heavy.
Therapeutic Method:
In the process of the course of disease, adopt the formula of the embodiment of the present invention 1, decoct into decoction oral, every day 2 times, each 1 time sooner or later.Within every 7 days, be a course for the treatment of, most patient 1-2 the course for the treatment of cures, and refractory patient 2-4 the course for the treatment of of falling ill of a specified duration cures.
Therapeutic outcome:
The clinical symptom disappearance of 95% patient after 3 days, state of an illness recovery from illness in 5-7 days.Wherein there are the transference cure recoveries from illness such as 5% heavier patient is dizzy after 7 days, Nausea and vomiting, follow up a case by regular visits to 3 years without recurrence.
Model case 1, Xu xx: female, 41 years old, people from Chengdu, Sichuan Province.Patient is in First episode on August 5th, 2000.Patient felt suddenly head in a flash at that time, weak all over, was at once recumbent on a sofa.Patient feels that object is in rotation, nose heave, can not stand up, dare not stand up; Be not steady on one's legs, head toward planting on the ground, holds up thing just can walk; Nausea and vomiting, keep one's eyes open the severity of telling, and intermittently tells, and tells once every a few minutes; Close one's eyes and also swoon, lie on a bed and also feel to turn, can only lie low, can not lie on one's side; Poor, dreaminess, the complexion of sleeping at ordinary times is poor; Be afraid of to listen noise, listened uncomfortable in chest after noise, feel bad; Head can not to the left and right, front and back rock, dizzy more severe during rolling; Special love is starved, and within one day, eats 5-7 and pauses (amount of often pausing does not reduce); Total urination time is many, and (urine volume does not reduce.I does not have diabetes); Have a bad temper, often fly into a rage; Sensation is often in a cold sweat or febrile perspiration, touches and touch less than antiperspirant with hands; The hypofunction of left ear audition.
Patient, to examination in hospital, is diagnosed as Menieres disease U.S..Patient is many hospital for treatment in locality, but the state of an illness can not get effective control all the time.So patient just starts her road of seeking medical advice.Patient goes around national various big hospital, integrative therapy, and curative effect is not good enough, and Relapse rate shows effect.
Patient is because the hydrolabyrinth of internal ear, causes lost pressure to increase, pressuring nerve and hair cell and occur dizzy.Give Chinese medicine preparation treatment prepared by patient's embodiment of the present invention 1.After patient takes a course for the treatment of, torment her persistent ailment for many years and finally fully recovered.
After three courses for the treatment of of patient's after treatment, drug withdrawal.Effect of follow-up visit by telephone, had no recurrence over 3 years.
Model case 2, what xx: man, 42 years old, Shanghai people.Existing more than 7 years of patient's paroxysmal vertigo, aggravation in recent years, attack times once increases to one month twice or thrice by half a year, before patient's onset of vertigo, first feels there is blast of hot air, by few abdomen upper punch to head; Feel surrounding scenes shake immediately, dark and dim eyesight.In locality, many large hospitals accept treatment to patient, and the state of an illness is not controlled.
Patient takes Chinese medicine preparation after 2 days prepared by the embodiment of the present invention 1, and symptom obviously alleviates, the transference cure of Nausea and vomiting.After patient takes a course for the treatment of, the transference cure of dizzy, dizzy, tinnitus.After two courses for the treatment of of patient medication, recovery from illness, drug withdrawal.Effect of follow-up visit by telephone, has no recurrence.
Model case 3, Deng xx: female, 45 years old, people from Lanzhou City, Gansu Province.Patient suffers from Menieres disease existing more than 5 years.Patient is dizzy owing to occurring after fatigue, is rotatory, and companion is tinnitus to a high-profile, auditory dysesthesia, and have nauseating, and vomiting, goes to a doctor in local hospital, be diagnosed as: Menieres disease.Patient accepts treatment at local hospital, and symptom is alleviated a little.But drug withdrawal, the state of an illness is recurrence just.In recent years, after patient per's outbreak, auditory dysesthesia all increases the weight of.Patient without otitis media and hypertension, the medical histories such as diabetes.
Patient is onset of vertigo at that time, and companion's tinnitus, conscious audition is very poor.Patient took the Chinese medicine preparation of the embodiment of the present invention 1 preparation after 2 days, and symptom obviously alleviates, and tinnitus disappears; After taking a course for the treatment of, symptom disappears completely.After three courses for the treatment of of patient's after treatment, recovery from illness.Effect of follow-up visit by telephone, has no recurrence.
Model case 4, thank to xx: man, 45 years old, Zhengzhou, Henan Province people.Patient is before 8 years, and prominent sense is dizzy, headache, tinnitus, auditory dysesthesia, nausea and vomiting, pale complexion, nervously to perspire, close order and lie in bed, and dare not stand up, through local hospital inspection, be diagnosed as Menieres disease U.S. (auditory vertigo disease).After patient takes oryzanol and downern, symptom slightly alleviates, but again and again shows effect over 8 years, and every 1-2 day shows effect once, and work, life are all affected.Patient is due to fatigue, and the state of an illness is shown effect again, and feelings will is not relaxed, and occurs the symptoms such as dizzy, tinnitus, Nausea and vomiting, pale complexion.The friend that patient's warp suffers from same disease with him introduces, and comes to go to a doctor.Patient sees that it is light without matter, and white and thin fur, examines its deep-rolling pulse.Be diagnosed as Menieres disease U.S. (Aural verigo).Give Chinese medicine preparation treatment prepared by patient's embodiment of the present invention 1.After patient takes 3 days, tinnitus, the symptom such as dizzy obviously alleviate, no longer nausea and vomiting.After patient takes a course for the treatment of, dizzyly not reaccess, tinnitus disappears, and auditory rehabilitation is normal.Further consultation, sees tongue normal, and arteries and veins bundle relaxes.After after treatment two courses for the treatment of, Effect of follow-up visit by telephone, has no recurrence over one year.
Model case 5, Lee xx: man, 39 years old, people from Shijiazhuang City, Hebei Province.Patient suffers from Menieres disease existing more than 5 years.Just start, patient does not take notice of very much, eats of medicine during morbidity, after disease is good, with regard to drug withdrawal.Do not take a routine treatment.In recent years, aggravation, the number of times of morbidity also increased than in the past.During morbidity, feel very dizzy, with one's eyes tight shut, dare not move, tinnitus, ear suffocation, also keep vomiting, and time serious, gall bladder juice all spues, and feels that the state of an illness is heavier during flu.
Patient took the Chinese medicine preparation of the embodiment of the present invention 1 preparation after 5 days, and symptom obviously alleviates; After taking a course for the treatment of, symptom disappears completely, and spirit is also vigorous.After patient continues to take three courses for the treatment of, recovery from illness.Effect of follow-up visit by telephone, has no recurrence.
Model case 6, high XX, female, 45 years old, people from Tianjin.Patient is dizzy, tinnitus, feels dizzy, and dare not stand.Patient has done the coherence check such as CT, magnetic resonance at local hospital, and check result is all normal.Patient, when morbidity, feels that health has kind of a sensation for past rear-inclined, and temple pain.Patient has seen a lot of hospital, has eaten a lot of medicine, has not all had effect.
Give Chinese medicine preparation treatment prepared by patient's embodiment 1.After patient takes second day, feel dizzy, the symptom of tinnitus obviously alleviates.After patient takes a course for the treatment of, symptom disappears substantially.Patient's after treatment course for the treatment of, thoroughly fully recover.
Model case 7, what XX: female, 37 years old, Jilin Province Ji'an City people.Patient the most over the past two years, always dizziness, headache, neck-shoulder pain, nausea and vomiting, in local hospital inspection, diagnostic result cervical vertigo.Western medical treatment, DeGrain, plan Chinese traditional treatment.Patient's readme: mainly headache, dizziness, time dizzy, feel dizzy, dare not stand, can only recumbency.When morbidity, neck and shoulder part also aches, sometimes nausea and vomiting.Give Chinese medicine preparation treatment prepared by patient's embodiment of the present invention 1.Patient eats up Third Mate's medicine, calls, and headache, dizzy symptom obviously alleviate.Patient adheres to taking medicine, and eat up a course for the treatment of, call, she there is no by sensory symptoms, even neck and shoulder part has not also ached.Treatment is full of confidence.Patient adheres to treatment.Patient takes the medicine of two courses for the treatment of, recovery from illness, drug withdrawal.Spent six months, she calls, and her drug withdrawal was never recurred till now.
Last it is noted that obviously, above-described embodiment is only for example of the present invention is clearly described, and the restriction not to embodiment.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here exhaustive without the need to also giving all embodiments.And thus the apparent change of amplifying out or variation be still among protection scope of the present invention.
Claims (1)
1. treat a Chinese medicine preparation for Menieres disease, it is characterized in that: described Chinese medicine preparation is formed by the Chinese drug preparation of following weight: Herba Agrimoniae 6 parts, Semen Cassiae 3 parts, Radix Salviae Miltiorrhizae 5 parts, 4 parts, Poria, 3 parts, Rhizoma Gastrodiae and the Rhizoma Atractylodis Macrocephalae 2 parts.
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CN105125676A (en) * | 2014-09-03 | 2015-12-09 | 张士远 | Medicine for treating Meniere's vertigo syndrome |
CN105287972A (en) * | 2015-11-30 | 2016-02-03 | 覃腾英 | Traditional Chinese medicine composition for curing Meniere's syndrome |
CN105963450A (en) * | 2016-07-08 | 2016-09-28 | 孟广千 | Traditional Chinese medicine composition for treating dizziness and faintness |
Citations (2)
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CN101134077A (en) * | 2007-09-14 | 2008-03-05 | 尹克华 | Traditional Chinese medicine for treating aural vertigo |
CN101564503A (en) * | 2009-04-22 | 2009-10-28 | 北京方策方程医药科技有限公司 | Dizzy reducing and paralysis curing pill and preparation thereof |
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CN101134077A (en) * | 2007-09-14 | 2008-03-05 | 尹克华 | Traditional Chinese medicine for treating aural vertigo |
CN101564503A (en) * | 2009-04-22 | 2009-10-28 | 北京方策方程医药科技有限公司 | Dizzy reducing and paralysis curing pill and preparation thereof |
Non-Patent Citations (1)
Title |
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仙鹤草_决明子治疗美尼尔氏病临床疗效研究;张明兰;《中医药信息》;20110110;第18卷(第1期);第29页 * |
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