CN102688362B - Medicine composition for treating epilepsy by combined treatment of traditional Chinese medicine and western medicine - Google Patents
Medicine composition for treating epilepsy by combined treatment of traditional Chinese medicine and western medicine Download PDFInfo
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Abstract
The invention discloses a medicine composition for treating epilepsy by combined treatment of traditional Chinese medicine and western medicine, comprising active ingredients and pharmaceutic adjuvant. The active ingredients comprise traditional Chinese medicines and western medicines. The traditional Chinese medicines comprise rhizoma cyperi, gambir plant, white silkworm, radix gentiana, radix scutellariae, blackend swallowwort root, radish seed, rhizoma arisaematis, root of pilose asiabell, bighead atractylodes rhizome, fructus aurantii, haematitum, amber and rhizoma acori graminei. The western medicines are diazepam, carbamazepine and phenytoin. The medicine composition disclosed by the invention is convenient for taking and has outstanding curative effects, does not relapse after recovery and has cure rate of more than 98%.
Description
art
The invention belongs to medical technical field, relate to a kind of pharmaceutical formulation, particularly a kind of pharmaceutical composition of therapy of combining Chinese and Western medicine epileptics.
Background technology
Epilepsy (epilepsy) is commonly called as " insane crazy, the epilepsy of sheep, epilepsy or epilepsy ", in < < Huang di's Canon of Medicine > > before in two thousand 2 hundred, just record to some extent, be the electric discharge of cerebral neuron paroxysmal abnormality, cause a kind of chronic disease of of short duration cerebral disorder.
Doctor trained in Western medicine is divided into idiopathy and the large class of Secondary cases (symptomatic) epilepsy two according to epileptics because of difference.The former refers to that this class patient's encephalopathy there is no structural change or the Developmental and Metabolic Disorder that can explain symptom, and has compared with close relationship with inherited genetic factors.Symptomatic epilepsy is because of in multiple brain disease damage and dysbolismus, as congenital diseases, antenatal period and perinatal disease (maternal infuries be infancy stage epilepsy commonly encountered diseases because of), something lost after hyperpyrexia convulsion, difficult labour, wound, infection, poisoning, intracranial tumor, cerebrovascular disease, Nutrition and Metabolism disease etc.The generation of epilepsy is relevant to neuron paradoxical discharge.During human body rest, the discharge frequency of a cerebral cortex pyramidal cell generally remains between 1～10 time/second, and in epileptic focus, one group of neuronic discharge frequency of morbid state can be up to hundreds of times per second.The reignition of epilepsy kitchen range cell mass high frequency, make the neuron that its aixs cylinder is contacted directly produce larger postsynaptic potential, thereby produce continuously, propagate, until inhibitory action (comprises the epilepsy activity of inhibitory nerve cell around, the recovery of glial cell to excitatory substance, and focus suppresses the participation of mechanism outward) outbreak is stopped.
Because route of transmission and scope are different, cause various forms outbreak.Epilepsy sexual activity may only involve the cerebral cortex in a region and no longer spread, and causes simple partial seizure; Excited in front central authorities, return or postcentral gyrus is transmitted to contiguous neuron by increasing of extracellular potassium ion after discharging, cause Jackson (Jackson) epilepsy; Epilepsy sexual activity often propagates into thalamus and formatio reticularis mesencephali by cerebral cortex by Descending Projections fiber, causes loss of consciousness, then spreads whole cerebral cortex by dispersivity thalamus projection system, produces a comprehensive tetanic grand mal of secondary.In addition, epilepsy complication comprises: the traumatic idiopathic epilepsy in (1) late period, often with the trend increasing the weight of, can be shown effect and be developed into generalized seizures by locality, seriously has hypomnesis, the performances such as personality disorder mental retardation.(2) cognitive disorders: the resolving ability to things is poor, comprise oneiroid state, the distortion of Time Perception, feeling of unreality, released state.(3) affective disorder: show as offending state, with inferiority complex or with depression.(4) aphasis: can generating portion aphasia or cataphasia many.(5) dysmnesia: to being familiar with things, produce the sensation of not experiencing, or can not recall fast the things living through in the past.(6) illusion: show with actual size, distance, the external form of object and produce difference.(7) can concurrent penetrance craniocerebral injury subdural hematoma and the disease such as intracerebral hematoma brain contusion fracture of skull.(8) hallucination: in the situation that changing without any the external world, can produce depending on, listen, variation and the illusion of the aspect such as taste, spatial impression and object imaging.
As a kind of obstinate disease, the traditional approach of current domestic epilepsy medical science and International Medical treatment epilepsy is mainly medicine and opens cranium hands excision, though these two kinds of Therapeutic Method have certain control action to the state of an illness, is difficult to thoroughly eradicate focus.
Summary of the invention
The deficiencies in the prior art, the object of the present invention is to provide a kind of pharmaceutical composition of therapy of combining Chinese and Western medicine epileptics.This pharmaceutical composition is as secret prescription handed down in the family from generation to generation, has advantages for the treatment of both the principal and secondary aspects of a disease, good effect, do not recur after more, determines that it is a kind of specific medicament for the treatment of epileptics after many decades clinical practice.
In view of in order to realize object of the present invention, inventor studies by lot of experiments, has finally obtained following three kinds of technical schemes:
The first: a kind of pharmaceutical composition of therapy of combining Chinese and Western medicine epileptics, by active component and pharmaceutic adjuvant, be prepared from, by weight, described active component is prepared from by the Chinese crude drug that contains Rhizoma Cyperi 55-95 part, hook fourth 75-175 part, Bombyx Batryticatus 105-195 part, Radix Gentianae 95-155 part, Radix Scutellariae 85-165 part, Radix Cynanchi Atrati 105-145 part, BUZI 105-195 part, Arisaema Cum Bile 105-195 part, Radix Codonopsis 135-165 part, Rhizoma Atractylodis Macrocephalae 85-165 part, Fructus Aurantii 55-145 part, Haematitum 80-170 part, succinum 55-145 part and Rhizoma Acori Graminei 55-145 part.
Further preferably, the pharmaceutical composition of described therapy of combining Chinese and Western medicine epileptics, described active component by 75 parts of Rhizoma Cyperis, hook 100 parts of 125 parts of fourths, 150 parts of Bombyx Batryticatus, 125 parts of Radix Gentianaes, 125 parts of Radix Scutellariaes, 125 parts of Radix Cynanchi Atratis, 150 parts of BUZI, 150 parts of Arisaema Cum Bile, 150 parts of Radix Codonopsis, 125 parts of the Rhizoma Atractylodis Macrocephalaes, 100 parts of Fructus Aurantiis, 125 parts of Haematitums, 100 parts of succinums and Rhizoma Acori Graminei and be prepared from.
The second: a kind of pharmaceutical composition of therapy of combining Chinese and Western medicine epileptics, by active component and pharmaceutic adjuvant, be prepared from, diazepam, carbamazepine and phenytoin Sodium that described active component is 1:15-25:5-15 by weight ratio form.
Preferably, the pharmaceutical composition of described therapy of combining Chinese and Western medicine epileptics, diazepam, carbamazepine and phenytoin Sodium that described active component is 1:20:10 by weight ratio form.
The third: a kind of pharmaceutical composition of therapy of combining Chinese and Western medicine epileptics, by active component and pharmaceutic adjuvant, be prepared from, described active component comprises following two parts:
(1) active ingredient of Chinese herbs: by weight, be prepared from by the Chinese crude drug that contains Rhizoma Cyperi 55-95 part, hook fourth 75-175 part, Bombyx Batryticatus 105-195 part, Radix Gentianae 95-155 part, Radix Scutellariae 85-165 part, Radix Cynanchi Atrati 105-145 part, BUZI 105-195 part, Arisaema Cum Bile 105-195 part, Radix Codonopsis 135-165 part, Rhizoma Atractylodis Macrocephalae 85-165 part, Fructus Aurantii 55-145 part, Haematitum 80-170 part, succinum 55-145 part and Rhizoma Acori Graminei 55-145 part;
(2) Western medicine active component: the diazepam, carbamazepine and the phenytoin Sodium that are 1:15-25:5-15 by weight ratio form.
Further preferably, the pharmaceutical composition of described therapy of combining Chinese and Western medicine epileptics, active ingredient of Chinese herbs wherein by weight, by 75 parts of Rhizoma Cyperis, hook 100 parts of 125 parts of fourths, 150 parts of Bombyx Batryticatus, 125 parts of Radix Gentianaes, 125 parts of Radix Scutellariaes, 125 parts of Radix Cynanchi Atratis, 150 parts of BUZI, 150 parts of Arisaema Cum Bile, 150 parts of Radix Codonopsis, 125 parts of the Rhizoma Atractylodis Macrocephalaes, 100 parts of Fructus Aurantiis, 125 parts of Haematitums, 100 parts of succinums and Rhizoma Acori Graminei and be prepared from; Diazepam, carbamazepine and phenytoin Sodium that Western medicine active component is wherein 1:20:10 by weight ratio form.
In most preferred embodiment of the present invention, the pharmaceutical composition of above-mentioned any therapy of combining Chinese and Western medicine epileptics, it is made into pill.
It should be noted that, the selected Chinese crude drug of the present invention has following pharmacologically active and function cures mainly:
Rhizoma Cyperi: the resolving depression of regulating the flow of vital energy, menstruction regulating and pain relieving.For stagnation of QI due to depression of the liver, breast, the side of body, abdominal distention, dyspepsia, menoxenia, amenorrhea dysmenorrhea, colic of cold type stomachache, distending pain of the breast.Derive from the dry rhizome of sedge dried tuber Cyperus rotundus L..
Hook fourth: have another name called Ramulus Uncariae Cum Uncis, heat clearing away suppressing the hyperactive liver, arresting convulsion relieves dizziness, high fever, infantile convulsions, epilepsy, etc.Control pediatric epilepsy scared Chi Zong, adult's blood pressure is higher, dizzy, dizzy, married woman's eclamposia.Derive from as Maguireothamnus speciosus Ramulus Uncariae Cum Uncis or Uncaria sinensis (Oliv.) Havil. and belong to the buckle branch of various plants together.
Bombyx Batryticatus: expelling wind for relieving convulsion, dissipating phlegm and resolving masses.For convulsion with spasms, laryngopharynx swelling and pain, submandibular lymph nodes inflammation, facial paralysis, skin pruritus.The larva that derives from 4～5 ages of Bombycidae insecticide silkworm Bombyx mori L. infects (or artificial vaccination) muscardine Beauveria bassiana (Bals.) Vuill. and lethal dry body.
Radix Gentianae: heat clearing and damp drying; Eliminating pathogen in the liver arresting convulsion.Jaundice due to damp-heat; Urine leaching pain; Swelling of the vulva pudendal pruritus; Damp-heat vaginal discharge; The feeling of fullness in the head headache of liver and gall excess-fire; Conjunctival congestion and swelling pain; Deaf ear is swollen; Hypochondriac pain bitter taste; Calentura convulsion with spasms.Derive from root and the rhizome of gentianaceae plant Radix Gentianae (Gentiana scabra Bge.), bar leaf Radix Gentianae (Gentiana manshurica Kitag.), three flower Radix Gentianae (Gentiana triflora Pall.) and Yunnan Radix Gentianae (Gentiana rigescens Franch.).
Radix Scutellariae: heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive, blood pressure lowering.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood is told nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.Derive from the dry root of labiate Radix Scutellariae Scutellaria baicalensis Georgi.
Radix Cynanchi Atrati: clearing away heat and cooling blood, inducing diuresis for treating stranguria syndrome, detoxification sore treatment.Enter nutrient blood for calentura pathogenic factor, fever of the body does not move back, yin asthenia generating intrinsic heat, puerperal deficiency-heat; Pyretic stranguria, stranguria with blood, sore and toxic. the diseases such as laryngopharynx swelling and pain, venom.Derive from asclepiadaceae plant Radix Cynanchi Atrati Cynanchum atratum Bge; Or the dry root and rhizome of Cynanchum versicolor Bunge Cynanchum versicolor Bge.
BUZI: have another name called Semen Raphani, cure mainly the de-swelling that helps digestion, lowering the adverse-rising QI to resolve phlegm.For stagnation of QI due to dyspepsia card, cough with asthma abundant expectoration, lack of appetite uncomfortable in chest.Derive from the mature seed for crucifer Radix Raphani Raphanus sativus L..
Arisaema Cum Bile: removing heat-phlegm, dispelling wind and relieving convulsion.For phlegm-heat cough, cough up phlegm yellow thick, middle wind-phlegm fan, demented infantile convulsion.The fine powder and cattle, sheep or the Fel Sus domestica that derive from Rhizoma Arisaematis (processed) process from strand, or are that Arisaema Cum Bile fine powder and cattle, sheep or Fel Sus domestica process through fermentation.
Radix Codonopsis: invigorating the spleen and replenishing QI, the effect of spleen invigorating lung benefiting.For deficiency of the spleen and lung, the cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency cough, interior-heat is quenched one's thirst etc.Derive from the dry root of Campanulaceae Radix Codonopsis Codonopsis pilosula (Franch.) Nannf..
The Rhizoma Atractylodis Macrocephalae: invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive.For insufficiency of the spleen lack of appetite, abdominal distention is had loose bowels, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.Derive from the dry rhizome of feverfew Rhizoma Atractylodis Macrocephalae Atractylodes macrocephala Koidz..
Fructus Aurantii: regulating the flow of QI to ease the stomach, the stagnant relieving distension of row.For the breast side of body stagnation of QI, distension pain, accumulation of food in the stomach and intes tine due to indigestion, stops in phlegm retention; Gastroptosis, proctoptosis, sub-official's prolapsus.Derive from the dry immature fruit of rutaceae Citrus aurantium Linn. Citrus aurantium L. and variety thereof.
Haematitum: suppressing the hyperactive liver town is contrary, cooling blood for hemostasis.Control eructation vomiting, dysphagia and regurgitation, asthma, infantile convulsion, spits blood, epistaxis, hemorrhoidal hamorrhage, hemorrhoid complicated by anal fistula, bleeding not during menses.Derive from the Ore of oxide-based mineral bloodstone, main containing iron sesquioxide (Fe
2o
3).
Succinum: calmness, diuresis, invigorates blood circulation.For infantile convulsion, epilepsy, cardiopalmus, insomnia, dysuria, dysurea, hematuria, amenorrhea.Derive from coniferale in ancient times, fabaceous resin, be embedded in the fossil sample material forming for a long time in stratum year.
Rhizoma Acori Graminei: removing dampness appetizing, the eliminating phlegm of having one's ideas straightened out, refreshment Fructus Alpiniae Oxyphyllae.Not hungry for gastral cavity painful abdominal mass, mouthful dysentery of keeping silent, coma epilepsy, forgetful deafness.Regulate the flow of vital energy, invigorate blood circulation, loose wind, dries.Control epilepsy, syncope due to accumulation of phlegm, calentura coma, forgetful, deafness with qi stagnation, ambition unhappiness, stomachache, stomachache, anemofrigid-damp arthralgia, swollen ulcer drug, traumatic injury.Derive from the rhizome of acorus gramineus araceae plant.
Inventor is clinically through studying for many years, treat and observing, obtained pharmaceutical composition of the present invention, this medicine has tranquillizing the mind by relieving convulsion, the spasmolytic of eliminating the phlegm, dispersing swelling and dissipating binds, regulate the flow of vital energy, heat clearing and damp drying, eliminating fire and detoxication, have one's ideas straightened out refresh oneself, calm, analgesic effect, for the treatment of epileptics, there is the advantage that treating both the principal and secondary aspects of a disease, curative effect spy are good, do not recur after more, and taking convenience, do not recur after more, cure rate reaches 98%, through clinical observation, take medicine a few days ago, extremely indivedual heads have any to have dizzy spells, and do not need drug withdrawal after symptom, can die away after several days.These conclusions are to come in practice, and pass through again practical proof, and determined curative effect, for numerous epileptics' healing has brought Gospel.
The specific embodiment
Form is described in further detail foregoing of the present invention again by the following examples, but this should be interpreted as to the scope of the above-mentioned theme of the present invention only limits to following embodiment, all technology realizing based on foregoing of the present invention all belong to scope of the present invention.
Embodiment 1: the preparation of pill
(1) preparation of red ball
Formula: Rhizoma Cyperi 75g, hook fourth 125g, Bombyx Batryticatus 150g, Radix Gentianae 125g, Radix Scutellariae 125g, Radix Cynanchi Atrati 125g, BUZI 150g, Arisaema Cum Bile 150g, Radix Codonopsis 150g, Rhizoma Atractylodis Macrocephalae 125g, Fructus Aurantii 100g, Haematitum 125g, succinum 100g and Rhizoma Acori Graminei 100g.
The preparation process of Chinese medicine: take Chinese crude drug by above-mentioned formula, except Haematitum, get respectively and claim various Chinese crude drugs to clean, dry, pulverize, by Rhizoma Cyperi 75g, hook fourth 125g, Bombyx Batryticatus 150g, Radix Gentianae 125g, Radix Scutellariae 125g, Radix Cynanchi Atrati 125g, BUZI 150g, Arisaema Cum Bile 150g, Radix Codonopsis 150g, Rhizoma Atractylodis Macrocephalae 125g, Fructus Aurantii 100g, Haematitum 125g, succinum 100g and Rhizoma Acori Graminei 100g take, mix, then soak 4 hours, decoct 10-20min with pot, after filtering, separate medicinal liquid, filtering residue is soaked 4 hours again, decoct 10-20min with pot, filter, merge medicinal liquid, again medicinal liquid is boiled into ointment.Then Haematitum is ground into medicated powder, gets 125g Haematitum medicated powder and add ointment to stir, add starch to make pill (red ball), totally 6840 balls.
(2) preparation of white ball
Formula: diazepam 2g carbamazepine 40g, phenytoin Sodium 20g.
Western medicine preparation process: take diazepam 2g, carbamazepine 40g, phenytoin Sodium 20g, make pill (white ball) after mixing with 75g starch, totally 360 balls.
The usage and dosage of said medicine is: red ball is each serving 38 balls, twice of every day; White ball is each serving 2 balls, twice of every day.Be a course for the treatment of half a year.
Clinical case
Example 1, Yan so-and-so, female, 47 years old, Bozhou City Qiaocheng District, Anhui Province north pass Yan Zhuan.Suffer from epileptics 20 years, each outbreak starts to be difficult to be subject to for feeling at heart, eye blackout, and the syncope of falling suddenly, whole body is twitched, on eye, turn over, spit out white foams, neck is turned round to a side, monthly shows effect 3-5 time, persistent period is can come for 8-10 minute, in a daze after waking up, headache, bradykinesia.Once continual treatment, took multiple Western medicine and just maintained symptom, and drug withdrawal is outbreak at once, because taking for a long time Western medicine, causes mind to slow up, and expression in the eyes is stupefied, was unwilling and others' talk, to others' enquirement reaction extreme difference, and can not manage household affairs.From 2005, take pill prepared by the embodiment of the present invention 1, be divided into white ball and red ball, taking dose ratio is: red ball is each serving 38 balls, twice of every day; White ball is each serving 2 balls, twice of every day.Having taken altogether trimestral medicine has fully recovered (half course for the treatment of).A normal people now completely.
Example 2, king so-and-so, female, 56 years old, Anhui Province's Bozhou City, the chief of taxation office.She narrates 6 years old epileptics obtaining, morbidity start the syncope of falling in a swoon for dizziness, dim eyesight, suddenly, whole body tic, spits out white foams, on eye, turn over, within about 10 minutes, can wake up and come, monthly show effect 8-10 time, never be interrupted treatment, once arrived Fuyang catgut embedding for treatment mistake, also to various big hospitals such as Shenzhen, treated, and eaten multiple Western medicine and all do not obtained desirable effect, the Western medicine of taking with the passing of time month after month just maintains symptom.From August nineteen ninety-five, take treatment epileptics pill medicine prepared by the embodiment of the present invention 1; Take symptom after three months and be clearly better, sleep is good, in high spirits, memory, taken continuously (2 courses for the treatment of) recovery from illness 1 year.A normal person now completely.
Example 3, Jiang, female, 44 years old, the doctor of Bozhou City the People's Hospital, Anhui Province.She narrates 11 years old epileptics, start outbreak at the moment once the black syncope of falling, whole body tic, spit out white foams, on two, turn over, neck is turned round to a side, continues can come for about 6 minutes, after waking up, eye is sent out straight, bradykinesia, headache, feels run-down, never be interrupted treatment, took various western medicine results undesirable.The pill of preparing by the embodiment of the present invention 1 from June, 2005, symptom takes a turn for the better after two months, has taken continuously recovery from illness three courses for the treatment of (a year and a half).
Example 4, Yang, female, 22 years old, Anhui Province's Bozhou City, its mother narrates 10 years old epileptics obtaining, dizzy before each outbreak, fall down, drop tears, spit out white foams suddenly, keep growling in the mouth, urinary incontinence, more than the 10 minute persistent period of outbreak can be waken up and be come, wake up and come to have a headache afterwards, dizziness, hypomnesis, never be interrupted treatment, taken many Chinese medicine and western medicine effect undesirable.From in JIUYUE, 2010, taken pill prepared by the embodiment of the present invention 1, just started to be not suitable with, take rear epigastric discomfort, vomiting, not drug withdrawal after one month symptom start to take a turn for the better, just take a course for the treatment of (half a year) has fully recovered.
Example 5, marquis so-and-so, man, 24 years old, Huatuo town, Bozhou City Qiaocheng District, Anhui Province.Its father's narration, the epileptics obtaining for 4 years old, each outbreak is fallen in a swoon suddenly at ground syncope, whole body is twitched, spit out white foams, on eye, turn over, neck is turned round to a side, within 8 minutes, can wake up and come, monthly attack times is more frequent, never be interrupted treatment, once in Bozhou City Qiaocheng District, Anhui Province tee pipe town hospital, done the hands art of sunkening cord several times, to no effect, in Cao County, Shandong, from back, did one time hands art, there is no effect, in Yucheng County, Henan Province, perform an operation in conjunction with infusion treatment, effect is also undesirable, afterwards again to Beijing Aviation hospital research Affiliated Hospital from the beginning the portion of taking done a major operation, 80,000 yuan of Operation Fees, symptom is without improvement, treatment epileptics Western medicine all take all over, because permanent Western medicine causes mind to slow up, expression in the eyes is stupefied, to others' enquirement reaction extreme difference, can not go out alone action, and disablement, from on March 8th, 2012, take pill prepared by the embodiment of the present invention 1, show effect 4-5 first 10 day every day, after having taken continuously one month, symptom takes a turn for the better, twice of the outbreak in a day having, the outbreak in one day having once, about 1 minute persistent period, just wake up and come, outbreak in several days once after two months, even 10 days, outbreak in 8 days once.
Example 6, Zhu, man, 21 years old, Bozhou City Qiaocheng District, Anhui Province Lee's bar.Its mother's narration, the epileptics of suffering from for 8 years old, there is not sensation before outbreak, suddenly the syncope of falling, twitches, and on eye, turns over, spit out white foams, abundant expectoration, neck is turned round to a side, about 5 minutes persistent period, can wake up and come, monthly once, regular, once with regard to one day, outbreak in one day is more than 7-9 times, because long-term taking Western medicine causes dementia, to others' enquirement reaction extreme difference.From in May, 2011, take pill prepared by the embodiment of the present invention 1, take complete once no outbreak course for the treatment of (half a year), taken continuously 4 recoveries from illness course for the treatment of, now in high spirits, also become vivaciously, be a normal person completely.
Example 7, Lee so-and-so, female, 28 years old, tee pipe town, Bozhou City Qiaocheng District, Anhui Province, narrate the epileptics of suffering from for 11 years old, before outbreak quietly chirp, dizzy, fall in a swoon suddenly, syncope, whole body is twitched, on eye, turn over, spit out white foams, neck is turned round to a side, continue to wake up for 5-6 minute and come, headache after waking up, once went to Xiamen, Beijing, Deng hospital, treated, took several Western medicine, curative effect is undesirable, from in January, 2011, take pill prepared by the embodiment of the present invention 1, take previous month effect undesirable, continue to take after three months and be clearly better, take three recoveries from illness course for the treatment of.
Example 8, Zhang, man 26 years old, side, elegance and talent middle school, the Bozhou City north pass, Anhui Province.Its mother's narration, the epileptics of suffering from for 25 years old, outbreak for the first time starts expression in the eyes to be sent out directly, and looping on the ground turns, continue just to regain consciousness for about three minutes, once hyperpyrexia 39 was spent grand mal once afterwards, and suddenly syncope turns on two, whole body is twitched, spit out white foams, continue to wake up for 4 minutes and come, severe headache after waking up, hypomnesis, malaise, monthly shows effect more than 3 times, and Zeng Quguo Bengbu Medical College fails to respond to any medical treatment, Qu Liao Beijing Tiantan Hospital neurosurgery again, done a lot of coherence checks, taken several Western medicine, effect is undesirable.From in February, 2012, take pill prepared by the embodiment of the present invention 1, take three moonsets and showed effect, now in high spirits, memory, happy, also can as normal person, work.
Example 9, Piao so-and-so, female, 44 years old, Room 401,62#4 unit in the Dagang District Fu Hua of Tianjin, chief of office.Within 13 years old, suffer from epileptics, before each outbreak, quietly chirp, keep growling in the mouth, fall down suddenly, drop tears, urinary incontinence, was never interrupted treatment, took many Chinese medicine and western medicine invalid.From in December, 1996, take pill prepared by the embodiment of the present invention 1, take a turn for the better (half a year) course for the treatment of, 4 recoveries from illness course for the treatment of.
Example 10, Yang, female, 28 years old, Anhui Province's Bozhou City.Mother narrates 6 years old and suffers from epileptics, before each outbreak, a slice is unintelligible at the moment, fall down suddenly, drop tears, in the mouth chirp cluck,coo, urinary incontinence, tic of the limbs, on eye, turn over, 4 minutes persistent period can wake up, never be interrupted treatment, rub Shanghai large hospital, Beijing Tiantan Hospital, the hospitals such as Beijing 301 Hospital all go to treat, also all are normal to have done a series of coherence check, she requires Beijing 301 Hospital to perform an operation to her, hospital dare not do to her, so for many years Western medicine all take all over effect undesirable, taken in January, 2010 after pill prepared by the embodiment of the present invention 1, taken a moonset outbreak, she had stopped medicine afterwards, within 2 years, all do not have outbreak once, 2 years to show effect later six months twice, now continue again to take the pill medicine for the treatment of epileptics of the present invention.
By above clinical case, can find, medicine of the present invention has for the treatment of epileptics the advantage that treating both the principal and secondary aspects of a disease, curative effect spy are good, do not recur after more, and taking convenience, do not recur after more, cure rate reaches 98%, through clinical observation, take medicine a few days ago, extremely indivedual heads have any to have dizzy spells, and do not need drug withdrawal after symptom, can die away after several days.These conclusions are to come in practice, and pass through again practical proof, and determined curative effect, for numerous epileptics' healing has brought Gospel.
Claims (2)
1. a pharmaceutical composition for therapy of combining Chinese and Western medicine epileptics, is characterized in that: by active component and pharmaceutic adjuvant, be prepared from, described active component is comprised of following two parts:
(1) active ingredient of Chinese herbs: by weight, be prepared from by the Chinese crude drug that contains Rhizoma Cyperi 55-95 part, hook fourth 75-175 part, Bombyx Batryticatus 105-195 part, Radix Gentianae 95-155 part, Radix Scutellariae 85-165 part, Radix Cynanchi Atrati 105-145 part, BUZI 105-195 part, Arisaema Cum Bile 105-195 part, Radix Codonopsis 135-165 part, Rhizoma Atractylodis Macrocephalae 85-165 part, Fructus Aurantii 55-145 part, Haematitum 80-170 part, succinum 55-145 part and Rhizoma Acori Graminei 55-145 part;
(2) Western medicine active component: the diazepam, carbamazepine and the phenytoin Sodium that are 1:15-25:5-15 by weight ratio form.
2. the pharmaceutical composition of therapy of combining Chinese and Western medicine epileptics according to claim 1, it is characterized in that: described active ingredient of Chinese herbs by weight, by 75 parts of Rhizoma Cyperis, hook 100 parts of 125 parts of fourths, 150 parts of Bombyx Batryticatus, 125 parts of Radix Gentianaes, 125 parts of Radix Scutellariaes, 125 parts of Radix Cynanchi Atratis, 150 parts of BUZI, 150 parts of Arisaema Cum Bile, 150 parts of Radix Codonopsis, 125 parts of the Rhizoma Atractylodis Macrocephalaes, 100 parts of Fructus Aurantiis, 125 parts of Haematitums, 100 parts of succinums and Rhizoma Acori Graminei and be prepared from; Diazepam, carbamazepine and phenytoin Sodium that described Western medicine active component is 1:20:10 by weight ratio form.
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| CN201210204892.8A Expired - Fee Related CN102688362B (en) | 2012-06-20 | 2012-06-20 | Medicine composition for treating epilepsy by combined treatment of traditional Chinese medicine and western medicine |
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